GenProp0280 |
cobalt import system (CbtAB - proposed)~The pair of genes making up this property have been proposed to comprise a cobalt ion imorter for the biosynthesis of vitamin B12 (cobalamin). Evidence for this assignment includes 1) prediction of five trans-membrane segments in CbtA and a single additional trans-membrane segment and a C-terminal histidine-rich motif likely to be a metal-binding site in CbtB, 2) positional gene linkage with known B12 biosynthesis genes, 3) upstream proximity of B12 transcriptional regulatory sites, 4) the absence of other known cobalt import systems and 5) the obligate co-localization of CbtA and CbtB. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|