Get results CSV file
Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
Component_48853 DNA mismatch repair protein MutS (mutS1) None - {{∅}} True - {{t}} Unconfirmed presence
Component_48854 DNA mismatch repair protein MutL None - {{∅}} True - {{t}} Unconfirmed presence
Component_48855 MutH (or other) mismatch endonuclease None - {{∅}} None - {{∅}} Unexplained
GenProp0225 mismatch repair~The combination of MutS (the MutS1 branch but not the MutS2 branch of the MutS family) and MutL leads to a general mechanism for mismatch exision and repair (MMR). Other proteins, recruited by MutS1 and MutL, act to clip (MutH or other endonuclease), remove (UvrD), and resynthesize one strand in the region containing the mismatch. MMR constrasts in its generality with the targeting of specific mismatches by various base excision repair (BER) glycosylases and with variants of MMR that act on specific mismatches. In Escherichia coli and related species that contain the endonuclease MutH and the DNA adenine methylation protein Dam, lack of methylation marks the newly synthesized strand; the mismatch is resolved by excision, removal, and resynthesis of a piece of that strand. MMR is referred to as methyl-directed mismatch repair in this subset of species with MMR. None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_61357 TIGR01070 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_61356 TIGR00585 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_61359 TIGR02248 HMM None - {{∅}} None - {{∅}} Unexplained