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Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
Evidence_219 TIGR00838 HMM True - {{t}} True - {{t}} Confirmed presence
Component_249 argininosuccinate lyase True - {{t}} True - {{t}} Confirmed presence
Component_247 ornithine carbamoyltransferase True - {{t}} True - {{t}} Confirmed presence
Component_248 argininosuccinate synthase True - {{t}} True - {{t}} Confirmed presence
GenProp0117 arginine biosynthesis from ornithine, carbamoyl-p and aspartate~The arginine biosynthesis pathway is a three step process and a part of the urea cycle.[2] The first enzyme, ornithine carbamoyltransferases (OTCase) carries out the reaction anabolically in arginine biosynthesis, but in some cases, it carries out catabolic reactions. Most OTCases are homotrimers, but the homotrimers are organized into dodecamers built from four trimers in at least two species; the catabolic OTCase of Pseudomonas aeruginosa is allosterically regulated, while OTCase of the extreme thermophile Pyrococcus furiosus shows both allostery and thermophily.[1] The third step of the pathway yields L-arginine by argininosuccinate lyase, and the amino acid can be cleaved by arginase, yielding urea and reconstituting ornithine. L-arginine also can be utilized in the creatine biosynthesis. True - {{t}} True - {{t}} Confirmed presence
Evidence_218 TIGR00032 HMM True - {{t}} True - {{t}} Confirmed presence
Evidence_217 TIGR00658 HMM True - {{t}} True - {{t}} Confirmed presence