GenProp0114 |
nucleotide excision repair~One mechanism of DNA repair is nucleotide excision repair. Single-stranded cuts are made on both sides of a DNA lesion and the oligomer between the cuts is removed. Very few species lack this mechanism, although the insect endosymbiont Buchnera aphidicola is an example. In bacteria, the excinuclease UvrABC performs only this function, so the presence of any one of the three subunits suggests the mechanism is (or was) present. Also required is UvrD or a related helicase with similar effect, but this helicase acts in other processes as well. A large number of genes are active in eukaryotes. The characteristic size of the oligomer removed is also different in eukaryotes. The status of nucleotide excision repair in the archaea is not fully defined. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
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