GenProp0023 |
glyoxylate shunt~The glyxoylate shunt consists of two enzymes, isocitrate lyase and malate synthase. Its function is generally anaplerotic, meaning that it replenishes TCA cycle intermediates. Isocitrate (one intermediate) becomes succinate (one intermediate) plus glyoxylate. Glyoxylate plus an acetyl group from acetyl-CoA becomes malate, a second intermediate, for a gain of one. Acetyl groups, such as from fatty acid metabolism, by means of this pathway, can provide TCA cycle intermediates for use in amino acid biosynthesis and other biosynthetic pathways. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
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