GenProp1074 |
type V secretion~Type V secretion systems (T5SS) are most commonly the classical monomeric autotransporters (type Va), in which a C-terminal outer membrane (OM) beta barrel domain functions as a translocator through the OM for an N-terminal passenger domain of the same polypeptide chain. Many type Va autotransporters cleave autocatalytically to release the passenger domain. In type Vb systems, called two-partner secretion systems, the passenger and translocator domains are in separate polypeptides. Additional variant forms Vc, Vd, and Ve have also been described. A special type of signal peptide (PF13018) tethers the nascent polypeptide chain to the Sec apparatus in some autotransporters to allow proper completion of C-terminal domain folding in the OM. |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
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