GenProp0845 |
protein sorting system, KxYKxGKxW class~Analogous to YSIRK, this property describes a subclass of N-terminal signal sequence in Firmicutes (low-GC Gram-positive bacteria). As with YSIRK, many proteins with this N-terminal domain have an LPXTG C-terminal anchor. However, most of these proteins have extended regions of low-complexity sequence, usually serine-rich. We propose that this signal domain is recognized by cellular machinery that delays protein translocation until glycosylation or other post-translational modifications are complete. |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
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