Evidence_82159 |
TIGR01819 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Evidence_82164 |
TIGR01916 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_60609 |
LPPG:Fo 2-phospho-L-lactate transferase |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Evidence_82160 |
TIGR03552 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
GenProp0792 |
7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) biosynthesis~7,8-didemethyl-8-hydroxy-5-deazariboflavin, or FO, is the chromophore of coenzyme F420. Several enzymatic steps convert FO to F420 (see GenProp0791). FO is also the chromophore of a cyanobacterial DNA photoreactivating enzyme. The two key enzymes of this pathway, encoded by CofG and CofH in Methanocaldococcus jannaschii, are encoded by fusion proteins in certain lineages. The fusion protein in Mycobacterium smegmatis is designated FbiC (F420 BIosynthesis C). The precursors are a pyrimidine intermediate from riboflavin biosynthesis and the 4-hydroxyphenylpyruvate precursor of tyrosine, so expressing FbiC in Escherichia coli is sufficient for FO biosynthesis. |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Evidence_82162 |
TIGR03550 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Evidence_82163 |
GenProp0792 GENPROP |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_60614 |
F420-O:gamma-glutamyl ligase |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Evidence_85833 |
TIGR04443 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Evidence_82161 |
TIGR03551 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_60621 |
NADPH-dependent F420 reductase |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_64057 |
coenzyme gamma-F420-2:alpha-L-glutamate ligase |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Evidence_82165 |
TIGR03553 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_60610 |
lactoylphosphate guanylyltransferase |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_60613 |
FO biosynthesis |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_60612 |
FO synthase, CofG subunit |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
GenProp0791 |
coenzyme F420 biosynthesis~The chromophore of coenzyme F420 is 7,8-didemethyl-8-hydroxy-5-deazaflavin, or FO, which is also used in a cyanobacterial DNA photoreactivating enzyme. Modification of FO to create coenzyme F420 includes the GTP-dependent addition of two glutamate residues in Methanococcus jannaschii and five or six in Mycobacterium bovis. CofF, which caps the gamma-glutamyl tail after two glutamates, occurs only the archaea. |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_60611 |
FO synthase, CofH subunit |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Evidence_82171 |
TIGR01915 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_60615 |
F420 biosynthesis protein FbiB, C-terminal domain |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|