GenProp0778 |
protein sorting system, GlyGly-CTERM/rhombosortase~The GlyGly-CTERM domain, previously called the gammaproteobacterial enzyme C-terminal transmembrane domain or rhombotail, appears to be a protein sorting signal analogous to LPXTG and PEP-CTERM. Every genome that encodes a set of GlyGly-CTERM proteins also encodes a rhomboid family enzyme, designated rhombosortase, in a many-to-one relationship. Rhomboid proteases are serine proteases with the active site Ser within the membrane, and they are capable of cleaving hydrophobic transmembrane segments. In general, genomes that encode GlyGly-CTERM proteins and rhombosortase also encode a type 2 secretion system (T2SS). Several GlyGly-CTERM proteins have been shown to undergo T2SS-mediated secretion. |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|