GenProp0744 |
glyoxalase pathway, glutathione dependent~Glyoxalase I and glyoxalase II are the enzymes lactoylglutathione lyase (EC 4.4.1.5) and hydroxyacylglutathione hydrolase (EC 3.1.2.6), respectively. This system detoxifies methylglyoxal and other highly reactive aldehydes. Glutathione serves a cofactor; variants of this pathway may occur where glutathione is replaced by another cofactor such as trypanothione in Trypanosoma cruzi (see PMID:16958620). |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
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