GenProp0739 |
iron-sulfur cluster assembly CsdA-CsdE system~The heteromeric complex of CsdA and CsdE plays a role in iron-sulfur (Fe-S) cluster biosynthesis, as do the better-known systems ISC, SUF, and NIF. CdsA, a homolog of SufS, IscS, and NifS, is a cysteine desulfurase catalytic subunit. CdsE, a SufE homolog, physically interacts and accepts a sulfur at Cys-61 (numbered as in Escherichia coli). In contrast to sulfur-accepting components such as NifU and IscU, CsdE does not bind iron and is not viewed as a scaffold on which Fe-S cluster biosynthesis can be completed prior to transfer to other proteins. Rather, this simplicity of this system may reflect a limited role for the maturation of specific Fe-S cluster-containing proteins. |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
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