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Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
Evidence_75242 PF03079 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_75245 TIGR01694 HMM None - {{∅}} False - {{f}} Unconfirmed absence
Evidence_75252 GenProp0732 GENPROP None - {{∅}} True - {{t}} Unconfirmed presence
GenProp0729 methionine salvage from methylthioadenosine~Methylthioadenosine (MTA) is a sulfur-containing by-product from the use of S-adenosylmethionine in spermidine or polyamine biosynthesis and certain other pathways. A series of reactions, with considerable species-specific variation, recycles MTA to methionine in a wide range of organisms. In a new nomenclature, these genes are now designated mtn (MethylThioNucleoside). An interesting enzyme in this system is MtnD, the aci-reductone dioxygenase. This enzyme has two different enzymatic activities, depending on whether Ni2+ or Fe2+ is bound. The action of the single enzyme MtnP is replaced by two enzymes, MtnN and MtnK in some species. Likewise, the enolase-phosphatase MtnC is replaced by MtnW and MtnX in the Bacillus lineage. The final step in the pathway, a transamination that generates methionine from 2-keto-4-methylthiobutyrate, apparantly can be catalyzed by a large number of functional analogs using different amino donors, and so is not included explicitly in the reconstruction. None - {{∅}} True - {{t}} Unconfirmed presence
Component_54281 methylthioribose-1-phosphate isomerase None - {{∅}} True - {{t}} Unconfirmed presence
Component_54283 aci-reductone dioxygenase None - {{∅}} True - {{t}} Unconfirmed presence
Component_54289 2,3-diketo-5-methylthiopentyl-1-phosphate enolase None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_75250 TIGR03332 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Component_54285 5-methylthioribose kinase None - {{∅}} True - {{t}} Unconfirmed presence
GenProp0730 methylthioadenosine to methylthioribose-1-phosphate via MTR~This property exists to describe a branch in the methionine salvage pathway in which MtnN followed by mtnK replaces the single step of MtnP. None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_75241 TIGR03328 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Component_54287 2,3-diketo-5-methylthiopentyl-1-P to aci-reductone None - {{∅}} True - {{t}} Unconfirmed presence
Component_54286 MTA to MTR-1-P None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_75247 TIGR01691 HMM None - {{∅}} False - {{f}} Unconfirmed absence
Evidence_75243 TIGR01704 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Component_54282 methylthioribulose-1-phosphate dehydratase None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_75246 GenProp0730 GENPROP None - {{∅}} True - {{t}} Unconfirmed presence
Component_54290 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_75251 TIGR03333 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_75248 TIGR00512 HMM None - {{∅}} True - {{t}} Unconfirmed presence
GenProp0732 methionine salvage enolase-phosphate pair MtnW/MtnX~In many species with methionine salvage from methylthioadenosine, a single protein (MtnC) acts as an enolase-phosphatase. However, in Bacillus subtilis and related species, the enolase and phosphate are separate proteins designated MtnW and MtnX. The former resembles RuBisCO and the latter belongs to the HAD superfamily hydrolases. None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_75244 TIGR01767 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Component_54284 methylthioadenosine nucleosidase None - {{∅}} True - {{t}} Unconfirmed presence