| Component_51511 |
phosphate acetyltransferase |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| Evidence_68287 |
TIGR02188 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
| Component_51513 |
acetate--CoA ligase |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
| Component_51512 |
via acetyl phosphate: GenProp0478 |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| Component_51514 |
direct with ATP/AMP: GenProp0480 |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
| Evidence_68281 |
TIGR00016 HMM |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| Component_51510 |
acetyl kinase |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| GenProp0478 |
acetyl-CoA -- acetate interconversion via acetyl phosphate~Acetate and acetyl-CoA can be interconverted by any of several routes. This pathway utilizes acetyl phosphate as an intermediate. This system is used in E. coli and other bacteria for the utilization of acetate as a carbon source [1]. Alternatively, the reactions may be run in the catabolic direction in fermentations in order to produce ATP and excrete acetate. Detection of the phosphate acetyltransferase is via a TIGRFAMs equivalog in some cases, while in others the discrimination between substrate specificities for acetate and butyrate (PF01515) is unclear. In the absence of an equivalog hit, when a gene adjacent to the kinase and in an apparent operon and hits the PFAM subfamily and the genomic context does not otherwise indicate the handling of butyrate, the gene will be manually included. A member of PF01515 which is distal from the acetate kinase in Thermotoga has been experimentally characterized [3] and has also been manually included. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| GenProp0479 |
acetate -- acetyl-CoA interconversions~acetate and acetyl-CoA can be interconverted for a number of purposes including utilization of acetate as in acetate fermentation, excretion of acetate in the fermentation of other compounds and the biosynthesis of acetyl-CoA for other purposes. Several different single-step and multi-step pathways are summarized in this property. The state of this property will be YES if any of the component pathways are found and the value field will hold the number of pathways found. |
None - {{∅}} |
Both - {{t},{f}} |
Unconfirmed contradictory |
|
| Evidence_68282 |
TIGR00651 HMM |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| Evidence_68286 |
GenProp0480 GENPROP |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
| GenProp0480 |
acetyl-CoA biosynthesis from acetate, direct~This property's sole component is the enzyme acetyl-CoA ligase which hydrolyses ATP to AMP in the process of ligating acetate to coenzyme A. This enzyme acts essentially irreversibly in the direction of AcCoA biosynthesis and utilizes an enzyme-bound acyl-adeylate (AMP-Ac) intermediate [1]. The purpose of this property is for comparison with the various other ways of interconverting acetate and acetyl-CoA. |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
| Evidence_68285 |
GenProp0478 GENPROP |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|