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Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
GenProp0305 cysteine biosynthesis~The biosynthesis of the amino acid cysteine may be achieved via several routes. Most commonly serine is the starting point (GenProp0218), while in the archaea a mis-charged cys-tRNA bearing O-phosphoserine is modified (GenProp0304). True - {{t}} True - {{t}} Confirmed presence
Evidence_85853 GenProp0304 GENPROP None - {{∅}} False - {{f}} Unconfirmed absence
Component_48840 serine O-acetyltransferase True - {{t}} True - {{t}} Confirmed presence
Component_64077 cysteine biosynthesis True - {{t}} True - {{t}} Confirmed presence
Evidence_61338 TIGR01138 HMM None - {{∅}} False - {{f}} Unconfirmed absence
Component_51214 O-phosphoseryl-tRNA synthetase None - {{∅}} False - {{f}} Unconfirmed absence
Evidence_85852 GenProp0218 GENPROP True - {{t}} True - {{t}} Confirmed presence
Component_48841 cysteine synthase True - {{t}} True - {{t}} Confirmed presence
GenProp0218 cysteine biosynthesis from serine~The conversion of L-serine to L-cysteine takes two enzymatic steps, described here. The first step involves Serine acetyl-transferase, and the second step involves acetylserine lyase which forms L-cysteine. True - {{t}} True - {{t}} Confirmed presence
Evidence_65816 TIGR02539 HMM None - {{∅}} False - {{f}} Unconfirmed absence
Component_51215 Sep-tRNA:Cys-tRNA synthase None - {{∅}} False - {{f}} Unconfirmed absence
Evidence_61340 TIGR01172 HMM True - {{t}} True - {{t}} Confirmed presence
GenProp0304 cysteine biosynthesis, tRNA-dependent~Methanocaldococcus jannaschii is a model archaeal species that lacks a direct cys--tRNA ligase. In a system analogous to pyrrolysine and (in many species) asparagine tRNA aminoacylation, the tRNA is misacylated and then the attached amino acid is modified. This two-step pathway is conducted by proteins in the families of MJ1660 (sepS) and MJ1678 (pscS). This pathway assumes 0-phosphoserine, whose biosynthesis is proposed to require D-3-phosphoglycerate dehydrogenase (TIGR01327) and an unidentified aminotransferase. None - {{∅}} False - {{f}} Unconfirmed absence
Evidence_61339 TIGR01139 HMM True - {{t}} True - {{t}} Confirmed presence
Evidence_65815 TIGR00470 HMM None - {{∅}} False - {{f}} Unconfirmed absence