Evidence_63391 |
TIGR02297 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_50880 |
5-carboxymethyl-2-hydroxymuconate delta-isomerase (5.3.3.10) |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Evidence_63401 |
TIGR02309 HMM |
False - {{f}} |
True - {{t}} |
Unexpected presence |
|
Evidence_63390 |
TIGR02296 HMM |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Component_50879 |
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase (1.2.1.60) |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Evidence_63414 |
TIGR02311 HMM |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Evidence_63415 |
TIGR02312 HMM |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Component_50886 |
bifunctional decarboxylase/isomerase, C-terminal |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Evidence_63397 |
PF02962 HMM |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Evidence_63440 |
TIGR02332 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Evidence_63393 |
TIGR02299 HMM |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Component_50881 |
bifunctional decarboxylase/isomerase, N-terminal |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
GenProp0231 |
4-hydroxyphenylacetate degradation~4-hydroxyphenylacetic acid, a degradation product of tyrosine via one of several routes, of phenylalanine via phenylacetate, and of environmental DDT is metabolized in this pathway to the common metabolites succinate and pyruvate via homoprotocatechuate. 4-hydroxyphenylacetic acid may also be found in the environment and transported into the cell. The genes encoding the components of this pathway are often organized into apparent operons which include regulatory elements as well as a variety of transport systems. A number of genomes show partial evidence of the pathway based on homologs of the well-characterized enzymes from other species. Often, promising candidates for the missing steps are found in the vicinity. These are suggestive of enzymes which have been adapted from ancestral sequences having a different function. Of course, the possibility exists that it is the entire pathway that has been modified in these species and it is other structurally related compounds that are being metabolized instead of 4-hydroxyphenylacetic acid. |
False - {{f}} |
Both - {{t},{f}} |
Contradictory presence |
|
Evidence_63392 |
TIGR02298 HMM |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Evidence_63400 |
TIGR02305 HMM |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Evidence_63386 |
TIGR02295 HMM |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Evidence_63402 |
TIGR02310 HMM |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Evidence_63398 |
TIGR02303 HMM |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Component_50887 |
succinate-semialdehyde dehydrogenase |
False - {{f}} |
True - {{t}} |
Unexpected presence |
|
Component_50922 |
regulatory protein, HpaR |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_50883 |
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Evidence_63405 |
TIGR01780 HMM |
False - {{f}} |
True - {{t}} |
Unexpected presence |
|
Component_50919 |
probable 4-hydroxyphenylacetate transporters |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_50877 |
4-hydroxyphenylacetate 3-monooxygenase, small subunit |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Evidence_63420 |
TIGR02313 HMM |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Component_50882 |
2-oxo-hepta-3-ene-1,7-dioate hydratase |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|
Component_50885 |
4-hydroxyphenylacetate 3-monooxygenase, large subunit |
False - {{f}} |
True - {{t}} |
Unexpected presence |
|
Evidence_63446 |
TIGR02337 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_50884 |
regulatory protein, HpaA |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_50878 |
3,4-dihydroxyphenylacetate 2,3-dioxygenase (1.13.11.15) |
False - {{f}} |
False - {{f}} |
Confirmed absence |
|