GenProp0166 |
mreBCD system~The bacterial MreBCD proteins are involved in rod shape determination and have a postulated role in the regulation of septum-specific peptidoglycan synthesis [1]. Members of the actin-like MreB family of proteins localize as a helical filament in bacteria and are important for determining cylindrical cell shape. Recent results show that new cell wall biosynthesis occurs along a helical track dependent on one of these actin homologs, providing new insights into bacterial cell growth, division and shape [2]. MreC and MreD are membrane-associated proteins. MreC is an essential gene in B. subtilis; cells lacking sufficient quantities of MreC undergo morphological changes, namely, swelling and twisting of the cells, which is followed by cell lysis [3]. MreC and MreD may be involved in the regulation of cell-shape-related protease expression [5]. There is evidence of the existence of a separate rod-shape determining system in rod-shaped bacteria lacking the MreBCD system [4]. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
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