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Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
Evidence_27902 TIGR01804 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Component_15577 glycine betaine dehydrogenase None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_27901 TIGR01810 HMM None - {{∅}} False - {{f}} Unconfirmed absence
Evidence_75295 TIGR03384 HMM None - {{∅}} False - {{f}} Unconfirmed absence
GenProp0147 glycine betaine biosynthesis from choline~As a coping mechanism against osmotic stress, prokaryotic organisms accumulate osmolytes or osmoprotectants from exogenous sources, to counterbalance elevated osmolarities in the environment without affecting overall cell metabolism and structural integrity [1]. One of the most efficient osmoprotectants found in the environment is the compound glycine betaine [1]. Both gram positive and gram negative bacteria mediate osmotolerance either by direct uptake of glycine betaine from the environment, or by synthesis from exogenously supplied choline [2,3]. This property reflects the biosynthesis of the osmoprotectant glycine betaine from choline [4,5]. Biosynthesis of glycine betaine occurs via a two-step oxidative reaction requiring a terminal electron acceptor [2,3]. Choline dehydrogenase first catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, with subsequent oxidization by betaine aldehyde dehydrogenase into the osmoprotectant glycine betaine [2,3]. Both choline dehydrogenase and betaine aldehyde dehydrogenase are required for conversion of choline into glycine betaine [2,3]. None - {{∅}} Both - {{t},{f}} Unconfirmed contradictory
Component_54323 choline-responsive transcriptional repressor BetI None - {{∅}} False - {{f}} Unconfirmed absence
Component_15576 choline dehydrogenase None - {{∅}} False - {{f}} Unconfirmed absence