Evidence_27907 |
TIGR01227 HMM |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
GenProp0145 |
histidine degradation to glutamate~This pathway is involved in histidine utilization system (hut). HutP is the first gene in the hut operon encoding the hutHUIG operator and a positive regulator of the operon, activated allostatically in the presence of L-histidine. HutC represses the histidine utilization by binding the regulatory sites for the hutHUIG and hutF the divergent.In some species, histidine is converted to via urocanate and then formimino-L-glutamate to glutamate in four steps, where the fourth step is conversion of N-formimino-L-glutamate to L-glutamate and formamide. In others, that pathway from formimino-L-glutamate have two other possible alternatives. One is involved with the tetrahydrofolate (THF) dependent glutamate formiminotransferase interconverting L-glutamate and N-formimino-L-glutamate. The enzyme is bifunctional as it also catalyzes the cyclodeaminase reaction on N-formimino-THF, converting it to 5,10-methenyl-THF and releasing ammonia - part of the process of regenerating THF. The other alternative is involved with hutF (formiminoglutamate hydrolase). |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
Evidence_27890 |
TIGR01224 HMM |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
Evidence_27889 |
TIGR01228 HMM |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
Component_15560 |
imidazolonepropionase (hutI) |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
Evidence_27912 |
TIGR02024 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_15561 |
formimidoylglutamate deiminase/formiminoglutamase/glu-formyltransferase |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
Component_15578 |
formylglutamate deformylase/formiminoglutamase/glu-formyltransferase |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
Component_15559 |
urocanate hydratase (hutU) |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
Evidence_27913 |
TIGR02024 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Evidence_27908 |
TIGR02017 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Evidence_27888 |
TIGR01225 HMM |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
Evidence_27906 |
TIGR02022 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_15579 |
histidine utilization repressor (hutC) |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Evidence_27891 |
TIGR01227 HMM |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
Component_15558 |
histidine ammonia-lyase (hutH) |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
Evidence_27909 |
TIGR02018 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|