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Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
VariantPath-2-UPA00617 False - {{f}} True - {{t}} Unexpected presence
UER00669 glycerone phosphate from glycerol (oxidative route): step 2/2~1 ATP + 1 glycerone => 1 ADP + 1 glycerone phosphate. False - {{f}} True - {{t}} Unexpected presence
ULS00327 glycerone phosphate from glycerol (oxidative route) False - {{f}} True - {{t}} Unexpected presence
VariantPath-2-UPA00618 False - {{f}} None - {{∅},{t}} Absent
VariantPath-1-UPA00618 False - {{f}} None - {{∅},{t}} Absent
UCR00847 ATP + glycerol = ADP + sn-glycerol 3-phosphate False - {{f}} True - {{t}} Unexpected presence
UPA00618 glycerol degradation via glycerol kinase pathway~In bacteria, glycerol uptake is mediated by the glycerol diffusion facilitator, an integral membrane protein catalyzing the rapid equilibration of concentration gradients of glycerol across the cytoplasmic membrane. Intracellular glycerol is converted to glycerol-3-phosphate that is further metabolized to dihydroxyacetone phosphate (DHAP) by either of two membrane-bound enzymes, depending on the growth conditions. False - {{f}} None - {{∅},{t}} Absent
MUER9 Meta-UER 9~1 Quinone + 1 sn-glycerol 3-phosphate => 1 Hydroquinone + 1 glycerone phosphate. False - {{f}} None - {{∅}} Absent
UER00671 propane-1,3-diol from glycerol (reductive route): step 2/2~1 3-hydroxypropanal + 1 H(+) + 1 NADH => 1 NAD(+) + 1 propane-1,3-diol. False - {{f}} None - {{∅}} Absent
ULS00331 glycerone phosphate from sn-glycerol 3-phosphate (aerobic route) False - {{f}} None - {{∅}} Absent
VariantPath-1-UPA00617 False - {{f}} None - {{∅}} Absent
UCR01047 glycerol = 3-hydroxypropanal + H(2)O False - {{f}} None - {{∅}} Absent
UCR03119 NAD(+) + propane-1,3-diol = 3-hydroxypropanal + H(+) + NADH False - {{f}} None - {{∅}} Absent
UCR01034 NAD(+) + glycerol = H(+) + NADH + glycerone False - {{f}} None - {{∅}} Absent
UCR00849 Quinone + sn-glycerol 3-phosphate = Hydroquinone + glycerone phosphate False - {{f}} None - {{∅}} Absent
ULS00329 sn-glycerol 3-phosphate from glycerol False - {{f}} True - {{t}} Unexpected presence
UPA00617 glycerol fermentation~In the absence of an external oxidant, glycerol is consumed by a dismutation process involving two sub-pathways. Through one sub-pathway (oxidative route), glycerol is dehydrogenated by an NAD+-linked glycerol dehydrogenase (DhaD) to dihydroxyacetone. This product is then phosphorylated by dihydroxyacetone kinase (DhaK) and funnelled to the central metabolism. Through the other sub-pathway (reductive route), glycerol is dehydrated by coenzyme B12-dependent glycerol dehydratase (DhaB, DhaC, DhaE) to form 3-hydroxypropionaldehyde, which is reduced to the major fermentation product 1,3-propanediol by the NADH-linked 1,3-propanediol dehydrogenase (DhaT), thereby regenerating NAD+ [PMID: 9311132]. . False - {{f}} True - {{t}} Unexpected presence
UER00670 propane-1,3-diol from glycerol (reductive route): step 1/2~1 glycerol => 1 3-hydroxypropanal + 1 H(2)O. False - {{f}} None - {{∅}} Absent
ULS00328 propane-1,3-diol from glycerol (reductive route) False - {{f}} None - {{∅}} Absent
UPA00616 glycerol degradation~Degradation of glycerol, a trihydric alcohol. Two possible routes of glycerol catabolism have been proposed. In the first pathway, glycerol is phosphorylated to glycerol-3-phosphate by glycerol kinase, and then converted to dihydroxyacetone phosphate by glycerol-3-phosphate dehydrogenase. In the second pathway, glycerol is converted to dihydroxyacetone by NAD-dependent glycerol dehydrogenase, and then phosphorylated to dihydroxyacetone phosphate by dihydroxyacetone kinase. . False - {{f}} True - {{t}} Unexpected presence
ULS00330 glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route) False - {{f}} None - {{∅}} Absent
UCR01011 ATP + glycerone = ADP + glycerone phosphate False - {{f}} True - {{t}} Unexpected presence
UER00668 glycerone phosphate from glycerol (oxidative route): step 1/2~1 NAD(+) + 1 glycerol => 1 H(+) + 1 NADH + 1 glycerone. False - {{f}} None - {{∅}} Absent
UER00672 sn-glycerol 3-phosphate from glycerol: step 1/1~1 ATP + 1 glycerol => 1 ADP + 1 sn-glycerol 3-phosphate. False - {{f}} True - {{t}} Unexpected presence