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Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
UCR01184 O(2) + myo-inositol = D-glucuronate + H(2)O None - {{∅}} None - {{∅}} Unexplained
VariantPath-2-UER00148 Both - {{∅},{t,f}} True - {{t}} Ambiguous presence
UCR05661 2-deoxy-5-keto-D-gluconic acid + ATP = 6-phospho-5-dehydro-2-deoxy-D-gluconic acid + ADP Both - {{∅},{t,f}} None - {{∅}} Ambiguous
UER00146 acetyl-CoA from myo-inositol: step 5/7~1 2-deoxy-5-keto-D-gluconic acid + 1 ATP => 1 6-phospho-5-dehydro-2-deoxy-D-gluconic acid + 1 ADP. Both - {{∅},{t,f}} None - {{∅}} Ambiguous
UPA00111 myo-inositol degradation into D-glucuronate~Irreversible degradation of myo-inositol into D-glucuronic acid. None - {{∅}} None - {{∅}} Unexplained
UPA00076 myo-inositol degradation into acetyl-CoA~Degradation of myo-inositol, an abundant compound in soil. Myo-Inositol is also common and essential in plants. Several micro-organisms, including model organism Bacillus subtilis (PMID:9226270), can grow on inositol as the carbon source. It was thought that bacterial inositol catabolism is only required for efficient utilization of this compound. However, the inositol dehydrogenase of Sinorhizobium fredii not only catalyses the initial reaction step of inositol catabolism but also is involved in nitrogen fixation and competitiveness to nodulate soybeans (PMID:11274120). Furthermore, MocA and MocC of Sinorhizobium meliloti which participate in degradation of rhizopine (L-3-O-methyl-scyllo-inosamine), a symbiosis- specific compound found in alfalfa nodules, exhibited significant similarities to IolG and IolE involved in inositol catabolism of B. subtilis, respectively (PMID:9226270), and the inositol catabolism pathway was tightly linked with rhizopine utilization in S. meliloti (PMID:9802033). These facts implied an interesting relationship between bacterial inositol catabolism and plant/bacteria symbiosis for nitrogen fixation. Both - {{∅},{t,f}} True - {{t}} Ambiguous presence
UCR01183 NAD(+) + myo-inositol = H(+) + NADH + scyllo-inosose Both - {{∅},{t,f}} True - {{t}} Ambiguous presence
UCR08503 5-deoxy-D-glucuronic acid = 2-deoxy-5-keto-D-gluconic acid Both - {{∅},{t,f}} None - {{∅}} Ambiguous
UCR00706 3-oxopropanoate + CoA + NADP(+) = CO(2) + H(+) + NADPH + acetyl-CoA Both - {{∅},{t,f}} True - {{t}} Ambiguous presence
UCR05378 6-phospho-5-dehydro-2-deoxy-D-gluconic acid = 3-oxopropanoate + glycerone phosphate Both - {{∅},{t,f}} None - {{∅}} Ambiguous
VariantPath-1-UER00148 Both - {{∅},{t,f}} True - {{t}} Ambiguous presence
UPA00405 myo-inositol degradation~degradation of myo-inositol, one of nine distinct isomers of inositol. . Both - {{t,f}} True - {{t}} Ambiguous presence
UCR00705 3-oxopropanoate + CoA + NAD(+) = CO(2) + H(+) + NADH + acetyl-CoA Both - {{∅},{t,f}} True - {{t}} Ambiguous presence
UER00144 acetyl-CoA from myo-inositol: step 2/7~1 scyllo-inosose => 1 3D-3,5/4-trihydroxycyclohexane-1,2-dione + 1 H(2)O. Both - {{∅},{t,f}} None - {{∅}} Ambiguous
UCR08603 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H(2)O = 5-deoxy-D-glucuronic acid Both - {{∅},{t,f}} None - {{∅}} Ambiguous
UCR02782 scyllo-inosose = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H(2)O Both - {{∅},{t,f}} None - {{∅}} Ambiguous
ULS00069 D-glucuronate from myo-inositol None - {{∅}} None - {{∅}} Unexplained
UER00951 None~1 3-oxopropanoate + 1 CoA + 1 NAD(+) => 1 CO(2) + 1 H(+) + 1 NADH + 1 acetyl-CoA. Both - {{∅},{t,f}} True - {{t}} Ambiguous presence
UER00952 None~1 3-oxopropanoate + 1 CoA + 1 NADP(+) => 1 CO(2) + 1 H(+) + 1 NADPH + 1 acetyl-CoA. Both - {{∅},{t,f}} True - {{t}} Ambiguous presence
ULS00061 acetyl-CoA from myo-inositol Both - {{∅},{t,f}} True - {{t}} Ambiguous presence
UER00527 D-glucuronate from myo-inositol: step 1/1~1 O(2) + 1 myo-inositol => 1 D-glucuronate + 1 H(2)O. None - {{∅}} None - {{∅}} Unexplained
UER00920 acetyl-CoA from myo-inositol: step 4/7~1 5-deoxy-D-glucuronic acid => 1 2-deoxy-5-keto-D-gluconic acid. Both - {{∅},{t,f}} None - {{∅}} Ambiguous
UER00147 acetyl-CoA from myo-inositol: step 6/7~1 6-phospho-5-dehydro-2-deoxy-D-gluconic acid => 1 3-oxopropanoate + 1 glycerone phosphate. Both - {{∅},{t,f}} None - {{∅}} Ambiguous
UER00148 acetyl-CoA from myo-inositol: step 7/7~3-oxopropanoate + CoA + [NAD(+) or NADP(+)] => CO(2) + H(+) + acetyl-CoA + [NADH or NADPH]. Both - {{∅},{t,f}} True - {{t}} Ambiguous presence
UER00143 acetyl-CoA from myo-inositol: step 1/7~1 NAD(+) + 1 myo-inositol => 1 H(+) + 1 NADH + 1 scyllo-inosose. Both - {{∅},{t,f}} True - {{t}} Ambiguous presence
UER00145 acetyl-CoA from myo-inositol: step 3/7~1 3D-3,5/4-trihydroxycyclohexane-1,2-dione + 1 H(2)O => 1 5-deoxy-D-glucuronic acid. Both - {{∅},{t,f}} None - {{∅}} Ambiguous