| Prior-Knowledge | Description | Expectation | Prediction | Conclusion | Leaf Statistics |
|---|---|---|---|---|---|
| Component_94 | dihydrofolate reductase | None - {{∅}} | True - {{t}} | Unconfirmed presence | |
| Component_95 | dihydropteroate synthase | None - {{∅}} | True - {{t}} | Unconfirmed presence | |
| Component_97 | dihydrofolate synthase | None - {{∅}} | True - {{t}} | Unconfirmed presence | |
| Evidence_24 | TIGR01496 HMM | None - {{∅}} | True - {{t}} | Unconfirmed presence | |
| Evidence_27 | TIGR01498 HMM | None - {{∅}} | True - {{t}} | Unconfirmed presence | |
| Component_93 | GTP cyclohydrolase I | None - {{∅}} | False - {{f}} | Unconfirmed absence | |
| Evidence_22 | TIGR00063 HMM | None - {{∅}} | False - {{f}} | Unconfirmed absence | |
| GenProp0038 | tetrahydrofolate biosynthesis from GTP and PABA~Polyglutamylated tetrahydrofolate is the central cofactor of one-carbon metabolism and is biosynthesized from GTP, para-aminobenzoate (from chorismate), and glutamate in a six step reaction.[1] The first enzyme, GTP cyclohydrolase I, in the biosynthesis of tetrahydrofolate in prokaryotes, of tetrahydrobiopterin in vertebrates, and of pteridine-containing pigments in insects catalizes dihydroneopterin triphosphate from GTP. This pathway is carried out by 6 enzymes, and the complete pathway is absent in animals. | None - {{∅}} | Both - {{t},{f}} | Unconfirmed contradictory | |
| Component_98 | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | None - {{∅}} | True - {{t}} | Unconfirmed presence | |
| Evidence_23 | PF00186 HMM | None - {{∅}} | True - {{t}} | Unconfirmed presence | |
| Evidence_25 | TIGR00525 HMM | None - {{∅}} | False - {{f}} | Unconfirmed absence | |
| Evidence_26 | TIGR01499 HMM | None - {{∅}} | True - {{t}} | Unconfirmed presence | |
| Component_96 | dihydroneopterin aldolase | None - {{∅}} | False - {{f}} | Unconfirmed absence |