| ULS00173 | 
                    sirohydrochlorin from precorrin-2 | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UER00376 | 
                    siroheme from sirohydrochlorin: step 1/1~1 Fe2+ + 1 sirohydrochlorin => 2 H(+) + 1 siroheme. | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UPA00262 | 
                    siroheme biosynthesis~Biosynthesis of siroheme, the cofactor for sulfite and nitrite reductases. Siroheme is formed by methylation, oxidation, and iron insertion into the tetrapyrrole uroporphyrinogen III (Uro-III). | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | ULS00174 | 
                    siroheme from sirohydrochlorin | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | ULS00090 | 
                    precorrin-2 from uroporphyrinogen III | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UER00211 | 
                    precorrin-2 from uroporphyrinogen III: step 1/1~2 S-adenosyl-L-methionine + 1 uroporphyrinogen III => 2 S-adenosyl-L-homocysteine + 1 precorrin-2. | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UER00222 | 
                    sirohydrochlorin from precorrin-2: step 1/1~1 NAD(+) + 1 precorrin-2 => 1 H(+) + 1 NADH + 1 sirohydrochlorin. | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     |