| UCR00084 | 
                    H(2)O + 4 porphobilinogen = 4 NH(3) + hydroxymethylbilane | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | VariantPath-4-UPA00251 | 
                     | 
                    None - {{∅}} | 
                    None - {{∅},{t}} | 
                    Unexplained | 
                     | 
                
                
                    | UCR00036 | 
                    2 5-aminolevulinate = 2 H(2)O + porphobilinogen | 
                    True - {{t}} | 
                    True - {{t}} | 
                    Confirmed presence | 
                     | 
                
                
                    | VariantPath-3-UPA00251 | 
                     | 
                    None - {{∅}} | 
                    None - {{∅},{t}} | 
                    Unexplained | 
                     | 
                
                
                    | ULS00141 | 
                    protoporphyrin-IX from protoporphyrinogen-IX | 
                    None - {{∅}} | 
                    None - {{∅}} | 
                    Unexplained | 
                     | 
                
                
                    | UCR03197 | 
                    uroporphyrinogen III = 4 CO(2) + coproporphyrinogen-III | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UER00316 | 
                    5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2~1 H(+) + 1 L-glutamyl-tRNA(Glu) + 1 NADPH => 1 (S)-4-amino-5-oxopentanoic acid + 1 NADP(+) + 1 tRNA(Glu). | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | VariantPath-1-UPA00251 | 
                     | 
                    None - {{∅}} | 
                    None - {{∅},{t}} | 
                    Unexplained | 
                     | 
                
                
                    | VariantPath-2-UPA00251 | 
                     | 
                    None - {{∅}} | 
                    None - {{∅},{t}} | 
                    Unexplained | 
                     | 
                
                
                    | UER00321 | 
                    coproporphyrinogen-III from 5-aminolevulinate: step 4/4~1 uroporphyrinogen III => 4 CO(2) + 1 coproporphyrinogen-III. | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | ULS00138 | 
                    5-aminolevulinate from L-glutamyl-tRNA(Glu) | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UCR06895 | 
                    2 S-adenosyl-L-methionine + coproporphyrinogen-III = 2 5'-deoxyadenosine + 2 CO(2) + 2 L-methionine + protoporphyrinogen-IX | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UER00324 | 
                    protoporphyrin-IX from protoporphyrinogen-IX: step 1/1~3 O(2) + 1 protoporphyrinogen-IX => 3 H(2)O(2) + 1 protoporphyrin-IX. | 
                    None - {{∅}} | 
                    None - {{∅}} | 
                    Unexplained | 
                     | 
                
                
                    | UER00322 | 
                    protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1~1 O(2) + 1 coproporphyrinogen-III => 2 CO(2) + 2 H(2)O + 1 protoporphyrinogen-IX. | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UER00375 | 
                    5-aminolevulinate from glycine: step 1/1~1 glycine + 1 succinyl-CoA => 1 5-aminolevulinate + 1 CO(2) + 1 CoA. | 
                    None - {{∅}} | 
                    None - {{∅}} | 
                    Unexplained | 
                     | 
                
                
                    | UER00317 | 
                    5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2~1 (S)-4-amino-5-oxopentanoic acid => 1 5-aminolevulinate. | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UCR04109 | 
                    H(+) + L-glutamyl-tRNA(Glu) + NADPH = (S)-4-amino-5-oxopentanoic acid + NADP(+) + tRNA(Glu) | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UER00319 | 
                    coproporphyrinogen-III from 5-aminolevulinate: step 2/4~1 H(2)O + 4 porphobilinogen => 4 NH(3) + 1 hydroxymethylbilane. | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UPA00251 | 
                    protoporphyrin-IX biosynthesis~Biosynthesis of protoporphyrin-IX, a porphyrin derivative precursor of heme and chlorphyll compounds. | 
                    None - {{∅}} | 
                    None - {{∅},{t}} | 
                    Unexplained | 
                     | 
                
                
                    | UCR03222 | 
                    3 O(2) + protoporphyrinogen-IX = 3 H(2)O(2) + protoporphyrin-IX | 
                    None - {{∅}} | 
                    None - {{∅}} | 
                    Unexplained | 
                     | 
                
                
                    | UER00318 | 
                    coproporphyrinogen-III from 5-aminolevulinate: step 1/4~2 5-aminolevulinate => 2 H(2)O + 1 porphobilinogen. | 
                    True - {{t}} | 
                    True - {{t}} | 
                    Confirmed presence | 
                     | 
                
                
                    | UER00320 | 
                    coproporphyrinogen-III from 5-aminolevulinate: step 3/4~1 hydroxymethylbilane => 1 H(2)O + 1 uroporphyrinogen III. | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UCR03165 | 
                    hydroxymethylbilane = H(2)O + uroporphyrinogen III | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UCR00830 | 
                    glycine + succinyl-CoA = 5-aminolevulinate + CO(2) + CoA | 
                    None - {{∅}} | 
                    None - {{∅}} | 
                    Unexplained | 
                     | 
                
                
                    | UCR02272 | 
                    5-aminolevulinate = (S)-4-amino-5-oxopentanoic acid | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | ULS00139 | 
                    protoporphyrinogen-IX from coproporphyrinogen-III (O2 route) | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | ULS00171 | 
                    5-aminolevulinate from glycine | 
                    None - {{∅}} | 
                    None - {{∅}} | 
                    Unexplained | 
                     | 
                
                
                    | UCR03220 | 
                    O(2) + coproporphyrinogen-III = 2 CO(2) + 2 H(2)O + protoporphyrinogen-IX | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | ULS00140 | 
                    protoporphyrinogen-IX from coproporphyrinogen-III (AdoMet route) | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | UER00323 | 
                    protoporphyrinogen-IX from coproporphyrinogen-III (AdoMet route): step 1/1~2 S-adenosyl-L-methionine + 1 coproporphyrinogen-III => 2 5'-deoxyadenosine + 2 CO(2) + 2 L-methionine + 1 protoporphyrinogen-IX. | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     | 
                
                
                    | ULS00172 | 
                    coproporphyrinogen-III from 5-aminolevulinate | 
                    None - {{∅}} | 
                    True - {{t}} | 
                    Unconfirmed presence | 
                     |