| UER00130 |
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1~1 5-amino-1-(5-phospho-D-ribosyl)imidazole + 1 CO(2) => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
| UCR06974 |
ATP + N(1)-(5-phospho-D-ribosyl)glycinamide + formate = ADP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + phosphate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UCR04463 |
ATP + H(2)O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine + ADP + L-glutamate + phosphate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00125 |
N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2~1 5-phospho-beta-D-ribosylamine + 1 ATP + 1 glycine => 1 ADP + 1 N(1)-(5-phospho-D-ribosyl)glycinamide + 1 phosphate. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UCR07404 |
5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + phosphate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UCR04325 |
10-formyl-5,6,7,8-tetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = 5,6,7,8-tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UCR04208 |
2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + phosphate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00124 |
N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2~1 5-phospho-alpha-D-ribose 1-diphosphate + 1 H(2)O + 1 L-glutamine => 1 5-phospho-beta-D-ribosylamine + 1 L-glutamate + 1 diphosphate. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| VariantPath-4-UPA00074 |
|
None - {{∅}} |
None - {{∅},{t}} |
Unexplained |
|
| VariantPath-3-UPA00074 |
|
None - {{∅}} |
None - {{∅},{t}} |
Unexplained |
|
| VariantPath-2-UPA00074 |
|
None - {{∅}} |
None - {{∅},{t}} |
Unexplained |
|
| VariantPath-1-UPA00074 |
|
None - {{∅}} |
None - {{∅},{t}} |
Unexplained |
|
| UER00131 |
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2~1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 1 ATP + 1 L-aspartate => 1 (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid + 1 ADP + 1 phosphate. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00127 |
N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (formate route): step 1/1~1 ATP + 1 N(1)-(5-phospho-D-ribosyl)glycinamide + 1 formate => 1 ADP + 1 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + 1 phosphate. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| ULS00052 |
N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (formate route) |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| ULS00470 |
5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00135 |
IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1~1 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide => 1 H(2)O + 1 IMP. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UCR04559 |
(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + fumarate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00942 |
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2~1 5-amino-1-(5-phospho-D-ribosyl)imidazole + 1 ATP + 1 bicarbonate => 1 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + 1 ADP + 1 phosphate. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| ULS00054 |
5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route) |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| ULS00051 |
N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route) |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| ULS00067 |
formate from 10-formyl-5,6,7,8-tetrahydrofolate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| ULS00471 |
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route) |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
| ULS00050 |
N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UCR01072 |
5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + H(2)O + L-glutamine |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| VariantPath-5-UPA00074 |
|
None - {{∅}} |
None - {{∅},{t}} |
Unexplained |
|
| VariantPath-6-UPA00074 |
|
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| VariantPath-7-UPA00074 |
|
None - {{∅}} |
None - {{∅},{t}} |
Unexplained |
|
| VariantPath-9-UPA00074 |
|
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| VariantPath-8-UPA00074 |
|
None - {{∅}} |
None - {{∅},{t}} |
Unexplained |
|
| ULS00473 |
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| ULS00448 |
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00132 |
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2~1 (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 fumarate. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| MUER19 |
Meta-UER 19~1 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide + 1 L-glutamine => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 1 L-glutamate. |
True - {{∅},{t}} |
True - {{t}} |
Confirmed presence |
|
| VariantPath-10-UPA00074 |
|
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00134 |
5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (formate route): step 1/1~1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 ATP + 1 formate => 1 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 ADP + 1 phosphate. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
| VariantPath-11-UPA00074 |
|
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00943 |
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2~1 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UCR04560 |
10-formyl-5,6,7,8-tetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = 5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| ULS00472 |
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route) |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00170 |
formate from 10-formyl-5,6,7,8-tetrahydrofolate: step 1/1~1 10-formyl-5,6,7,8-tetrahydrofolate + 1 H(2)O => 1 5,6,7,8-tetrahydrofolate + 1 formate. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR04558 |
5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + L-glutamate |
True - {{∅},{t}} |
True - {{t}} |
Confirmed presence |
|
| UPA00074 |
IMP biosynthesis via de novo pathway~The formation from simpler components of purine nucleotide IMP (inosine 5'phosphate). |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00129 |
5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2~1 2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine + 1 ATP => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole + 1 ADP + 1 phosphate. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UCR04144 |
5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + N(1)-(5-phospho-D-ribosyl)glycinamide + phosphate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UCR00944 |
10-formyl-5,6,7,8-tetrahydrofolate + H(2)O = 5,6,7,8-tetrahydrofolate + formate |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR07405 |
5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00128 |
5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2~1 ATP + 1 H(2)O + 1 L-glutamine + 1 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide => 1 2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine + 1 ADP + 1 L-glutamate + 1 phosphate. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UCR01127 |
H(2)O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR04591 |
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid + ADP + phosphate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UCR04209 |
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2) |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
| UER00126 |
N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1~1 10-formyl-5,6,7,8-tetrahydrofolate + 1 N(1)-(5-phospho-D-ribosyl)glycinamide => 1 5,6,7,8-tetrahydrofolate + 1 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00133 |
5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1~1 10-formyl-5,6,7,8-tetrahydrofolate + 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide => 1 5,6,7,8-tetrahydrofolate + 1 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| ULS00055 |
5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (formate route) |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
| ULS00056 |
IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UCR06975 |
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + ATP + formate = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + ADP + phosphate |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|