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Home page > Home > General informations > For teachers and students > Sequencing Strategies > Sequencing strategies

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Sequencing strategies





Introduction
Whole genome shotgun sequencing
Clone-by-clone sequencing

Introduction

The sequencing of large genomes remains an arduous enterprise, for which several strategies exist. All these strategies encounter the same problem: since sequencing machines can only deliver 1000 nucleotides per read at best, how can the ensemble of the genome sequence, which is thousands (bacteria) to millions (mammals) of times longer, be reconstituted?

Last update on 22 January 2008

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