Lien pour acceder au site du CEA
Site Genoscope en langue française Genoscope site in english El sitio Genoscope en español
Home page > Sequencing > Projects > Animals > Homo sapiens > Sequencing of a region near 16q12.1

All the versions of this article:

Homo sapiens

Sequencing of a region near 16q12.1

Project: Collaborative
State of the project: In progress



Townes-Brocks syndrome is a combination of malformations of the anus, the external ear, the thumbs and the kidney associated with deafness.

Transmission is autosomal dominant, expression is variable and penetrance is complete. The localization of the gene is 16q12.1, as determined from a reciprocal translocation. YAC clones, and P1 and PACs which overlap the chromosomal breakage point have been isolated. The project aims to sequence 3 clones (P1 and PAC) localized around the translocation breakpoint.

Last update on 11 January 2008

© Genoscope - Centre National de Séquençage
2 rue Gaston Crémieux CP5706 91057 Evry cedex
Tél:  (+33) 0 1 60 87 25 00
Fax: (+33) 0 1 60 87 25 14

Home | Overview | Projects | News | Press Panorama | Resources | Contact
Follow-up of the site's activity RSS 2.0 | Site Map | Credits | Copyright