CDSs classified by EGGNOG in COG category M
Acinetobacter baylyi ADP1 - chromosome ACIAD.1
M: CELLULAR PROCESSES AND SIGNALING -> Cell wall/membrane/envelope biogenesis
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OG ID | OG function | Label | Gene | Product | COG | PFAM short name | KO |
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3NJUG | This protein specifically catalyzes the removal of signal peptides from prolipoproteins | ACIAD0021 | lspA | prolipoprotein signal peptidase (Signal peptidase II.) | COG0597 | Peptidase_A8 | K03101 |
3NJ27 | peptidyl-prolyl cis-trans isomerase | ACIAD0065 | fklB | FKBP-type 22KD peptidyl-prolyl cis-trans isomerase (rotamase) | COG0545 | FKBP_C, FKBP_N | K03773 |
3NJF4 | Polysaccharide biosynthesis/export protein | ACIAD0070 | wza | polysaccharide export protein | COG1596 | Poly_export, SLBB | K01991 |
3NJSX | Belongs to the UDP-glucose GDP-mannose dehydrogenase family | ACIAD0072 | ugd | UDP-glucose 6-dehydrogenase | COG1004 | UDPG_MGDP_dh, UDPG_MGDP_dh_C, UDPG_MGDP_dh_N | K00012 |
1SA3F | glycosyl transferase family 2 | ACIAD0074 | putative glycosyl transferase family 2 | Glycos_transf_2 | |||
3NIR1 | RmlD substrate binding domain | ACIAD0076 | rmlB | dTDP-D-glucose-4,6-dehydratase | COG1088 | GDP_Man_Dehyd | K01710 |
3NM08 | Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose | ACIAD0078 | rmlD | dTDP-4-dehydrorhamnose reductase (dTDP-4-keto-L- rhamnose reductase) (dTDP-6-deoxy-L-mannose dehydrogenase) (dTDP-L- rhamnose synthetase) | COG1091 | RmlD_sub_bind | K00067 |
3NJY8 | Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis | ACIAD0079 | rmlA | dTDP-glucose pyrophosphorylase (glucose-1-phosphate thymidylyltransferase) | COG1209 | NTP_transferase | K00973 |
3NJVJ | Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose | ACIAD0080 | rmlC | dTDP-4-keto-6-deoxy-D-glucose-3,5-epimerase | COG1898 | dTDP_sugar_isom | K01790 |
1STQD | Glycosyl transferases group 1 | ACIAD0081 | putative glycosyl transferase family 1 | Glycos_transf_1 | |||
3NQM1 | Glycosyltransferase like family 2 | ACIAD0082 | putative glycosyl transferase family 2 (rhamnosyl transferase) | COG1216 | Glycos_transf_2 | K07011 | |
3NPSW | Glycosyl transferases group 1 | ACIAD0084 | putative glycosyl transferase family 1 (mannosyl transferase) | Glyco_transf_4, Glycos_transf_1 | |||
3NMRW | Belongs to the mannose-6-phosphate isomerase type 2 family | ACIAD0086 | epsM | bifunctional protein [Includes: Mannose-6-phosphate isomerase (Phosphomannose isomerase) (Pmi) (Phosphohexomutase); Mannose-1-phosphate guanylyl transferase (Gdp) (GDP-mannose pyrophosphorylase) (Gmp)] | COG0662, COG0836 | MannoseP_isomer, NTP_transferase | K16011 |
3NIGZ | Belongs to the UDP-glucose GDP-mannose dehydrogenase family | ACIAD0087 | putative UDP-glucose/GDP-mannose dehydrogenase | COG0677 | UDPG_MGDP_dh, UDPG_MGDP_dh_C, UDPG_MGDP_dh_N | K02474 | |
3NK1T | 3-beta hydroxysteroid dehydrogenase/isomerase family | ACIAD0088 | putative NAD-dependent epimerase/dehydratase (WbpP) | Epimerase | K02473 | ||
3NMJE | Glycosyltransferase Family 4 | ACIAD0090 | putative glycosyl transferase family 1 | Glyco_transf_4, Glycos_transf_1 | |||
3NKJC | Glycosyltransferase Family 4 | ACIAD0091 | putative glycosyl transferase family 1 | Glyco_trans_1_4, Glyco_transf_4 | |||
3NMAJ | Glycosyl transferases group 1 | ACIAD0092 | putative glycosyl transferase family 1 | Glyco_trans_1_4, Glyco_trans_4_2 | |||
3NKCB | Bacterial sugar transferase | ACIAD0093 | putative UDP-galactose phosphate transferase (WeeH) | Bac_transf | |||
3NIY7 | RmlD substrate binding domain | ACIAD0096 | putative dTDP-glucose-4,6-dehydratase/UDP-glucose 4-epimerase (WeeK) (WbpM) | CoA_binding_3, Polysacc_synt_2 | |||
3NKCB | Bacterial sugar transferase | ACIAD0098 | putative UDP-glucose lipid carrier transferase/glucose-1-phosphate transferase in colanic acid gene cluster (WcaJ) | COG2148 | Bac_transf, CoA_binding_3 | K03606 | |
3NKR1 | UTP-glucose-1-phosphate uridylyltransferase | ACIAD0099 | galU | UTP-glucose-1-phosphate uridylyltransferase | COG1210 | NTP_transferase | K00963 |
3NJGE | Belongs to the UDP-glucose GDP-mannose dehydrogenase family | ACIAD0100 | putative UDP-glucose 6-dehydrogenase (Ugd) (Udg) | COG1004 | UDPG_MGDP_dh, UDPG_MGDP_dh_C | K00012 | |
3NII4 | UDP-glucose 4-epimerase | ACIAD0102 | galE | UDP-glucose 4-epimerase (Galactowaldenase) (UDP-galactose 4-epimerase) | COG1087 | Epimerase | K01784 |
3NIXG | macromolecule glycosylation | ACIAD0103 | pglL | O-oligosaccharyltransferase | PglL_A, Wzy_C, Wzy_C_2 | ||
3NNNM | Pili assembly chaperone PapD, C-terminal domain | ACIAD0123 | putative pili assembly chaperone | PapD_C, PapD_N | |||
3NIFI | Belongs to the DapA family | ACIAD0130 | kdgD | 5-dehydro-4-deoxyglucarate dehydratase (5-keto-4-deoxy- glucarate dehydratase) | COG0329 | DHDPS | K01707 |
1T2BF | Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane | ACIAD0139 | putative outer membrane protein | ||||
3NMQ7 | Lysin motif | ACIAD0168 | LysM domain-containing protein | Hydrolase_2, LysM | |||
3NIWK | TonB dependent receptor | ACIAD0214 | putative outer membrane copper receptor (OprC) | COG1629 | Plug, TonB_dep_Rec | K02014 | |
3NIEB | Glycosyl hydrolases family 25 | ACIAD0226 | putative lysozyme | COG3757 | Glyco_hydro_25 | K07273 | |
3NJR0 | tail specific protease | ACIAD0257 | putative periplasmic carboxyl-terminal protease | COG0793 | Peptidase_S41 | K03797 | |
3NK5B | Belongs to the peptidase S11 family | ACIAD0262 | pbpG | D-alanyl-D-alanine endopeptidase, penicillin-binding protein 7 and penicillin-binding protein 8 | COG1686 | Peptidase_S11 | K07262 |
3NKJJ | Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) | ACIAD0270 | murD | UDP-N-acetylmuramoylalanine-D-glutamate ligase | COG0771 | Mur_ligase_C, Mur_ligase_M | K01925 |
3NJQ1 | Outer membrane efflux protein | ACIAD0278 | tolC | channel-tunnel spanning the outer membrane and periplasm segregation of daughter chromosomes | COG1538 | OEP | K12340 |
3NJEZ | OmpW family | ACIAD0314 | putative outer membrane protein W | COG3047 | OmpW | K07275 | |
3NMUN | Asp/Glu/Hydantoin racemase | ACIAD0318 | racD | D-aspartate racemase | COG1794 | Asp_Glu_race | K01779 |
3NNFJ | COG3209 Rhs family protein | ACIAD0339 | conserved hypothetical protein | ||||
3NJE9 | Pili assembly chaperone PapD, C-terminal domain | ACIAD0388 | acuD | fimbrial chaperone AcuD | COG3121 | PapD_C, PapD_N | K07346 |
3NIIR | Transfers the fatty acyl group on membrane lipoproteins | ACIAD0415 | lnt | apolipoprotein N-acyltransferase, copper homeostasis protein | COG0815 | CN_hydrolase | K03820 |
3NJCZ | Glycosyl transferase 4-like domain | ACIAD0482 | putative glycosyltransferase | Glyco_transf_4, Glycos_transf_1 | |||
3NJM6 | Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) | ACIAD0484 | lpxP | Lipid A biosynthesis (KDO) 2-(lauroyl)-lipid IVA acyltransferase (Heat shock protein B) | COG1560 | Lip_A_acyltrans | K02517 |
3NIUX | Gamma-glutamyltranspeptidase | ACIAD0485 | putative gamma-glutamyltranspeptidase | COG0405 | G_glu_transpept | K00681 | |
3NM4S | Gram-negative bacterial TonB protein C-terminal | ACIAD0507 | putative TonB | COG0810 | TonB_C | K03832 | |
3NJV6 | Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins | ACIAD0518 | lgt | prolipoprotein diacylglyceryl transferase | COG0682 | LGT | K13292 |
3NK7I | Belongs to the peptidase S41A family | ACIAD0552 | prc | carboxy-terminal protease for penicillin-binding protein | COG0793 | DUF3340, PDZ, Peptidase_S41 | K03797 |
3NJVX | Glycosyltransferase Family 4 | ACIAD0553 | putative glycosyl transferase | Glyco_transf_4, Glycos_transf_1 | |||
3NIR2 | Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane | ACIAD0564 | conserved hypothetical protein; putative PQQ enzyme repeat domain protein | COG1520 | PQQ_2, PQQ_3 | K17713 | |
3NM7H | Glycosyl transferase family 2 | ACIAD0572 | putative glycosyl transferase (GT2 family) | Glycos_transf_2 | |||
3NIJE | Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) | ACIAD0576 | conserved hypothetical protein | LolA | |||
3NM2D | Mitochondrial fission ELM1 | ACIAD0598 | conserved hypothetical protein | COG3660 | Mito_fiss_Elm1 | K07276 | |
3NK6S | COG0463 Glycosyltransferases involved in cell wall biogenesis | ACIAD0601 | putative lipopolysaccharide core biosynthesis glycosyl transferase LpsC | Glycos_transf_2 | |||
3NKPC | Glycosyl transferases group 1 | ACIAD0602 | putative glycosyltransferase | Glyco_transf_4, Glycos_transf_1 | |||
3NTK6 | Glycosyltransferase family 25 (LPS biosynthesis protein) | ACIAD0604 | putative glycosyltransferase involved in LPS biosynthesis | Glyco_transf_25 | |||
3NIQJ | Sporulation related domain | ACIAD0645 | conserved hypothetical protein | SPOR | |||
3NJ7Z | Belongs to the ompA family | ACIAD0653 | putative lipoprotein precursor | OmpA | |||
3NIUB | Belongs to the EPSP synthase family. MurA subfamily | ACIAD0660 | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase (Enoylpyruvate transferase) (UDP-N-acetylglucosamine enolpyruvyl transferase) (EPT) | COG0766 | EPSP_synthase | K00790 |
3NJM8 | Belongs to the ompA family | ACIAD0697 | putative Outer membrane protein precursor (OmpA-like) | COG2885 | OMP_b-brl, OmpA | K03286 | |
3NN59 | Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell | ACIAD0704 | mscL | mechanosensitive channel | COG1970 | MscL | K03282 |
3NIMC | Conserved TM helix | ACIAD0750 | conserved hypothetical protein; putative membrane protein | TM_helix | |||
3NIVF | Nucleoside-specific channel-forming protein, Tsx | ACIAD0769 | tsx | nucleoside-specific channel-forming protein | COG3248 | Channel_Tsx | K05517 |
3NN73 | Membrane | ACIAD0770 | conserved hypothetical protein | ||||
3NM18 | Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | ACIAD0784 | nolF | nodulation protein | HlyD_3 | ||
3NJPV | Involved in formation and maintenance of cell shape | ACIAD0826 | mreC | rod shape-determining protein | COG1792 | MreC | K03570 |
3NN3U | rod shape-determining protein MreD | ACIAD0828 | mreD | rod shape-determining protein | COG2891 | MreD | K03571 |
3NIVW | NmrA-like family | ACIAD0849 | putative dehydrogenase | Epimerase | |||
3NIW7 | Belongs to the ompA family | ACIAD0898 | putative outer membrane protein | OmpA | |||
3NT6T | Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane | ACIAD0909 | smpA | outer membrane lipoprotein | COG2913 | SmpA_OmlA | K06186 |
3NIUX | Gamma-glutamyltranspeptidase | ACIAD0929 | ggt | gamma-glutamyltranspeptidase precursor | COG0405 | G_glu_transpept | K00681 |
1SI2C | COG3209 Rhs family protein | ACIAD0943 | conserved hypothetical protein | ||||
3NIKZ | Belongs to the BCCT transporter (TC 2.A.15) family | ACIAD1012 | betT2 | high-affinity choline transporter (BCCT family) | COG1292 | BCCT | K02168 |
3NJ8M | Glycosyl transferase family 21 | ACIAD1030 | putative transport protein (VGP family) (Haemin storage system) (HmsR) | COG1215 | Glyco_tranf_2_3 | K11936 | |
3NIFT | Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors | ACIAD1061 | mtgA | monofunctional biosynthetic peptidoglycan transglycosylase | COG0744 | Transgly | K03814 |
3NT02 | RHS Repeat | ACIAD1078 | putative RHS-related protein | RHS_repeat | |||
3NNDC | NlpE N-terminal domain | ACIAD1085 | putative lipoprotein | NlpE | |||
3NJ50 | Belongs to the transpeptidase family. MrdA subfamily | ACIAD1101 | pbpA | penicillin-binding protein 2 | COG0768 | PBP_dimer, Transpeptidase | K05515 |
3NJBH | Dolichyl-phosphate-mannose-protein mannosyltransferase | ACIAD1117 | putative membrane glycosyltransferase (GT83 family) | PMT_2 | |||
3NJ1D | Glycosyltransferase like family 2 | ACIAD1119 | putative bactoprenol glycosyl transferase, phage origin | COG0463 | Glycos_transf_2 | K20534 | |
3NKSP | LppC putative lipoprotein | ACIAD1131 | conserved hypothetical protein; putative signal peptide | COG3107 | LppC | K07121 | |
3NJAK | COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) | ACIAD1138 | bifunctional protein [Includes: lytic murein transglycosylase C, membrane-bound (MtlD); putative cell wall hydrolase] | LysM, SLT | |||
3NJIY | Barrel-sandwich domain of CusB or HlyD membrane-fusion | ACIAD1157 | putative RND transporter, membrane fusion protein | COG0845 | HlyD_D23 | K07799 | |
3NJKG | Outer membrane efflux protein | ACIAD1160 | putative membrane channel protein | OEP | |||
3NJE2 | Belongs to the UDP-N-acetylglucosamine 2-epimerase family | ACIAD1175 | wecB | UDP-N-acetyl glucosamine-2-epimerase | COG0381 | Epimerase_2 | K01791 |
3NT04 | Glycosyl transferase family 21 | ACIAD1178 | putative glycosyltransferase | Glyco_tranf_2_3 | |||
3NIWC | Belongs to the peptidase S11 family | ACIAD1184 | putative D-ala-D-ala-carboxypeptidase, penicillin-binding protein | COG1686 | Peptidase_S11 | K07258 | |
3NIQN | OmpW family | ACIAD1199 | putative outer membrane W signal peptide protein | COG3047 | OmpW | K07275 | |
3NK5A | Belongs to the peptidase S11 family | ACIAD1225 | dacC | D-ala-D-ala-carboxypeptidase; penicillin-binding protein 5 (precursor) | COG1686 | PBP5_C, Peptidase_S11 | K07258 |
3NK2K | Peptidase family M23 | ACIAD1229 | nlpD | lipoprotein precursor | COG0739 | LysM, Peptidase_M23 | K06194 |
3NK04 | Peptidase family M48 | ACIAD1260 | conserved hypothetical protein; putative Zn-dependent protease with chaperone function | Peptidase_M48 | |||
3NJDC | Phospholipase | ACIAD1354 | putative phospholipase A1 precursor (PldA) | COG2829 | PLA1 | K01058 | |
3NJ00 | zinc metalloprotease | ACIAD1377 | putative membrane-associated Zn-dependent proteases 1 | COG0750 | PDZ_2, Peptidase_M50 | K11749 | |
3NJMK | Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane | ACIAD1378 | putative outer membrane protein | COG4775 | Bac_surface_Ag, POTRA | K07277 | |
3NJVP | Outer membrane protein (OmpH-like) | ACIAD1379 | putative outer membrane protein (OmpH) | COG2825 | OmpH | K06142 | |
3NJ49 | Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell | ACIAD1380 | lpxD | UDP-3-O-[3-hydroxylauroyl] glucosamine N-acyltransferase | COG1044 | Hexapep, Hexapep_2, LpxD | K02536 |
3NJGX | Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell | ACIAD1382 | lpxA | UDP-acetylglucosamine acyltransferase | COG1043 | Acetyltransf_11, Hexapep | K00677 |
3NKKX | Nucleoside-diphosphate-sugar epimerases | ACIAD1390 | conserved hypothetical protein | Semialdhyde_dh | |||
3NKGZ | Gram-negative bacterial TonB protein C-terminal | ACIAD1477 | conserved hypothetical protein; putative TonB-related protein | TonB_C | |||
3NJ4R | Arabinose 5-phosphate isomerase | ACIAD1482 | kdsD | D-arabinose 5-phosphate isomerase | COG0517, COG0794 | CBS, SIS | K06041 |
3NJQY | Outer membrane efflux protein | ACIAD1487 | putative outer membrane efflux protein, type I secretion protein | COG1538 | OEP | K12543 | |
3NKF2 | HlyD membrane-fusion protein of T1SS | ACIAD1489 | putative protein secretion efflux system, membrane fusion protein (hemolysin-type secretion transmembrane protein) (superfamily ABC, membrane) | COG0845 | Biotin_lipoyl_2, HlyD_3 | K12542 | |
3NT4I | Gram-negative bacterial TonB protein C-terminal | ACIAD1528 | putative tonB-like protein | COG0810 | TonB_C | K03832 | |
3NN7N | Glycosyl transferase family 2 | ACIAD1558 | putative glycosyl transferase (GT2 family) | Glycos_transf_2 | |||
3NT4J | Gram-negative bacterial TonB protein C-terminal | ACIAD1588 | putative tonB-like protein | COG0810 | TonB_C | K03832 | |
3NSQQ | Lipocalin-like domain | ACIAD1626 | putative outer membrane lipoprotein (lipocalin) | COG3040 | Lipocalin_2 | K03098 | |
3NJM9 | Mycolic acid cyclopropane synthetase | ACIAD1630 | cfa | cyclopropane-fatty-acyl-phospholipid synthase | COG2230 | CMAS | K00574 |
3NKMF | Mycolic acid cyclopropane synthetase | ACIAD1632 | putative cyclopropane-fatty-acyl-phospholipid synthase | COG2230 | CMAS | K00574 | |
3NIRJ | Acetyltransferase (GNAT) domain | ACIAD1637 | antibiotic resistance protein (acepita) | COG1247 | Acetyltransf_4 | K03823 | |
3NJT9 | SmpA / OmlA family | ACIAD1640 | putative antigen | OmpA, SmpA_OmlA | |||
3NMGF | Transglycosylase SLT domain | ACIAD1663 | conserved hypothetical protein | SLT | |||
3NSMF | LrgB-like family | ACIAD1673 | conserved hypothetical protein; putative membrane protein | LrgB | |||
3NKF0 | Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane | ACIAD1697 | dcaP | porin precurseur in catabolism of dicarboxylic acids | Sugarporin_N | ||
3NK6E | Carbohydrate-selective porin, OprB family | ACIAD1715 | quiX | porin | COG3659 | OprB | K07267 |
3NJEP | Mechanosensitive ion channel | ACIAD1869 | putative transporter with mechanosensitive ion channel. | COG0668 | MS_channel | K16053 | |
3NJJM | RmlD substrate binding domain | ACIAD1891 | putative UDP-galactose 4-epimerase (GalE-like) | COG1087 | Epimerase | K01784 | |
3NJ3H | Cell wall formation | ACIAD1945 | murB | UDP-N-acetylenolpyruvoylglucosamine reductase, FAD-binding | COG0812 | FAD_binding_4, MurB_C | K00075 |
3NIHT | Belongs to the KdsA family | ACIAD2002 | kdsA | 2-dehydro-3-deoxyphosphooctonate aldolase | COG2877 | DAHP_synth_1 | K01627 |
3NJE7 | Linear amide C-N hydrolases, choloylglycine hydrolase family | ACIAD2026 | putative choloylglycine hydrolase protein | COG3049 | CBAH | K01442 | |
3NN30 | NlpC/P60 family | ACIAD2149 | putative cell wall-associated hydrolases (invasion-associated proteins) | NLPC_P60 | |||
3NJFY | Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) | ACIAD2234 | mrcB | bifunctional protein [Includes penicillin-insensitive transglycosylase; penicillin-sensitive transpeptidase] (penicillin-binding protein 1B) | COG0744 | Transgly, Transpeptidase, UB2H | K05365 |
1MWUN | Outer membrane protein (Porin) | ACIAD2246 | putative outer membrane porin protein precursor | Porin_4 | |||
3NJBT | Peptidoglycan polymerase that is essential for cell wall elongation | ACIAD2263 | rodA | rod shape-determining protein | COG0772 | FTSW_RODA_SPOVE | K05837 |
3NKMR | Transglycosylase SLT domain | ACIAD2264 | mltB | membrane-bound lytic murein transglycosylase B | COG2951 | SLT_2 | K08305 |
3NJEK | Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides | ACIAD2265 | putative rare lipoprotein A family (RlpA-like) | COG0797 | DPBB_1 | K03642 | |
3NIQN | OmpW family | ACIAD2272 | conserved hypothetical protein; putative outer membrane protein | OmpW | |||
3NJDS | Gram-negative porin | ACIAD2319 | putative porin precursor | Porin_4 | |||
3NKDW | Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell | ACIAD2324 | lpxB | lipid A-disaccharide synthase | COG0763 | LpxB | K00748 |
3NK83 | Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria | ACIAD2362 | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase | COG1212 | CTP_transf_3 | K00979 |
3NJHV | Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) | ACIAD2363 | lpxK | tetraacyldisaccharide 4'-kinase (Lipid A 4'-kinase) | COG1663 | LpxK | K00912 |
3NJ0U | COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) | ACIAD2369 | putative nucleotidyl transferase | COG1208 | NTP_transferase | K00992 | |
3NJSZ | Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane | ACIAD2371 | ostA | organic solvent tolerance protein precursor or increased membrane permeability protein | COG1452 | OstA, OstA_C | K04744 |
3NIEI | Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation | ACIAD2372 | surA | peptidyl-prolyl cis-trans isomerase | COG0760 | Rotamase, Rotamase_3, SurA_N | K03771 |
3NII7 | TamB, inner membrane protein subunit of TAM complex | ACIAD2402 | conserved hypothetical protein | COG2911 | TamB | K09800 | |
3NIV8 | Surface antigen | ACIAD2403 | conserved hypothetical protein; putative outer membrane protein | COG0729 | Bac_surface_Ag, POTRA_TamA_1 | K07278 | |
3NJY7 | ErfK YbiS YcfS YnhG family protein | ACIAD2475 | conserved hypothetical protein; putative signal peptide | PG_binding_1, YkuD | |||
3NM4V | Lipocalin-like domain | ACIAD2568 | putative outer membrane lipoprotein | COG3040 | Lipocalin_2 | K03098 | |
3NK8H | Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner | ACIAD2584 | lepA | GTP-binding protein | COG0481 | EFG_C, GTP_EFTU, GTP_EFTU_D2, LepA_C | K03596 |
3NKQS | TonB C terminal | ACIAD2621 | tolA | tolerance to group A colicins, single-stranded filamentous DNA phage, required for OM integrity | COG3064 | Fibrinogen_BP, TonB_2 | K03646 |
3NKBN | Belongs to the ompA family | ACIAD2623 | pal | peptidoglycan-associated lipoprotein precursor | COG2885 | OmpA | K03640 |
3NIFD | Bacterial lipid A biosynthesis acyltransferase | ACIAD2638 | putative lipid A biosynthesis lauroyl acyltransferase | COG1560 | Lip_A_acyltrans | K02517 | |
3NIGK | MacB-like periplasmic core domain | ACIAD2641 | lolC | transport protein of outer membrane lipoproteins (ABC superfamily, membrane) | COG4591 | FtsX, MacB_PCD | K09808 |
3NIK7 | Outer membrane efflux protein | ACIAD2648 | conserved hypothetical protein; putative outer membrane efflux protein | OEP | |||
3NK8Q | OmpA family | ACIAD2682 | putative outer membrane lipoprotein | COG2885 | OmpA | K03286 | |
3NIZ9 | D-alanyl-D-alanine carboxypeptidase | ACIAD2699 | conserved hypothetical protein; putative membrane protein | COG5632 | Peptidase_M15_4 | K17733 | |
COG3209 | self proteolysis | ACIAD2704 | conserved hypothetical protein | ||||
COG3209 | self proteolysis | ACIAD2704 | conserved hypothetical protein | ||||
3NT02 | RHS Repeat | ACIAD2709 | hypothetical protein | RHS_repeat | |||
3NJV2 | COG3209 Rhs family protein | ACIAD2710 | hypothetical protein | ||||
3NK4E | Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane | ACIAD2824 | conserved hypothetical protein; putative protein (DcaP-like) | ||||
3NISE | Transglycosylase SLT domain | ACIAD2827 | putative periplasmic binding protein of transport/transglycosylase | SLT | |||
3NJTE | Transglycosylase SLT domain | ACIAD2832 | putative transglycosylase | SLT | |||
3NNIC | Recycling of diacylglycerol produced during the turnover of membrane phospholipid | ACIAD2837 | dgkA | diacylglycerol kinase | COG0818 | DAGK_prokar | K00901 |
3NJGY | Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane | ACIAD2898 | putative competence protein (ComL) | COG4105 | TPR_18 | K05807 | |
3NJDU | Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein | ACIAD2902 | lolB | outer-membrane lipoprotein precursor | COG3017 | LolB | K02494 |
3NNP5 | Acetyltransferase (GNAT) family | ACIAD2918 | putative acyltransferase | Acetyltransf_1 | |||
3NKC7 | Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) | ACIAD2937 | lolA | outer-membrane lipoproteins carrier protein | COG2834 | LolA | K03634 |
3NJZ0 | Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | ACIAD2943 | putative RND multidrug efflux membrane fusion protein MexA precursor | COG0845 | HlyD_D23 | K03585 | |
3NJR2 | Outer membrane efflux protein | ACIAD2945 | putative outer membrane protein oprM precursor | COG1538 | OEP | K18139 | |
3NJ0T | Carbohydrate-selective porin, OprB family | ACIAD2984 | putative glucose-sensitive porin (OprB-like ) | COG3659 | OprB | K07267 | |
3NIKB | LrgB-like family | ACIAD3007 | conserved hypothetical protein; putative membrane protein | LrgB | |||
3NK9B | MlaA lipoprotein | ACIAD3018 | putative lipoprotein precursor (VacJ) transmembrane | COG2853 | MlaA | K04754 | |
3NIPP | Mechanosensitive ion channel | ACIAD3026 | putative small conductance mechanosensitive ion channel | MS_channel | |||
3NMVT | Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins | ACIAD3049 | putative TonB_C domain-containing protein | TonB_2 | |||
3NMK0 | COG3209 Rhs family protein | ACIAD3087 | conserved hypothetical protein | ||||
3NKK6 | Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane | ACIAD3107 | putative minor lipoprotein | COG2980 | K03643 | ||
3NJBY | Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | ACIAD3109 | putative secretion protein (HlyD family) | COG0845 | HlyD_D23 | K13888 | |
3NIGG | Outer membrane efflux protein | ACIAD3111 | putative outer membrane protein precursor | OEP | |||
3NMTU | chlorophyll binding | ACIAD3114 | conserved hypothetical protein | ||||
3NJXX | COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) | ACIAD3157 | putative lytic murein transglycosylase, soluble (Slt) | COG0741 | SLT | K08309 | |
3NKHY | NAD(P)H-binding | ACIAD3234 | conserved hypothetical protein; putative nucleoside-diphosphate-sugar epimerase | NAD_binding_10 | |||
3NIIW | Provides the (R)-glutamate required for cell wall biosynthesis | ACIAD3257 | murI | glutamate racemase | COG0796 | Asp_Glu_race | K01776 |
3NK2E | Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis | ACIAD3322 | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (also involved in penicillin tolerance and control of the stringent response. Seems to directly or indirectly interact with relA to maintain it in an inactive form during normal growth.) | COG0761 | LYTB | K03527 |
3NSQG | Pili and flagellar-assembly chaperone, PapD N-terminal domain | ACIAD3335 | putative pili assembly chaperone (PapD-like) | COG3121 | PapD_N | K07346 | |
3NIXG | macromolecule glycosylation | ACIAD3337 | pglL | oligosaccharyltransferase | PglL_A, Wzy_C, Wzy_C_2 | ||
3NJYW | penicillin-binding protein | ACIAD3361 | mrcA | penicillin binding protein | COG0744 | PCB_OB, Transgly, Transpeptidase | K05366 |
3NJV1 | First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan | ACIAD3363 | mraY | phospho-N-acetylmuramoyl-pentapeptide transferase | COG0472 | Glycos_transf_4 | K01000 |
3NJ67 | Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein | ACIAD3364 | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (UDP-MurNAc-pentapeptide synthetase) (D-alanyl-D- alanine-adding enzyme) | COG0770 | Mur_ligase, Mur_ligase_C, Mur_ligase_M | K01929 |
3NKQI | Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan | ACIAD3365 | murE | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase | COG0769 | Mur_ligase_C, Mur_ligase_M | K01928 |
3NIFN | Catalyzes cross-linking of the peptidoglycan cell wall at the division septum | ACIAD3366 | ftsI | septum formation, penicillin binding protein 3, peptidoglycan synthetase | COG0768 | PBP_dimer, Transpeptidase | K03587 |
3NK1H | Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | ACIAD3376 | czcB | RND divalent metal cation efflux membrane fusion protein | COG0845 | HlyD_D23 | K15727 |
3NJYG | Outer membrane efflux protein | ACIAD3378 | czcC | outer membrane protein precursor | COG1538 | OEP | K15725 |
3NJKG | Outer membrane efflux protein | ACIAD3421 | putative outer membrane protein precursor | OEP | |||
3NJIY | Barrel-sandwich domain of CusB or HlyD membrane-fusion | ACIAD3424 | mdtA | membrane protein inolved in drug resistance | COG0845 | HlyD_D23 | K07799 |
3NJ7G | Mycolic acid cyclopropane synthetase | ACIAD3442 | putative methyltransferase | Methyltransf_25 | |||
3NIKZ | Belongs to the BCCT transporter (TC 2.A.15) family | ACIAD3460 | glycine betaine transport protein | COG1292 | BCCT | K02168 | |
3NJ9B | Mechanosensitive ion channel | ACIAD3477 | conserved hypothetical protein; putative membrane protein | MS_channel | |||
3NJGR | 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) | ACIAD3479 | kdtA | 3-deoxy-D-manno-2-octulosonate transferase | COG1519 | Glycos_transf_1, Glycos_transf_N | K02527 |
3NKBI | Peptidase family M23 | ACIAD3508 | putative peptidase | Peptidase_M23 | |||
3NJID | Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis | ACIAD3510 | lpxC | UDP-3-O-acyl-N-acetylglucosamine deacetylase | COG0774 | LpxC | K02535 |
3NK5E | Belongs to the MurCDEF family | ACIAD3516 | murC | UDP-N-acetylmuramate--alanine ligase | COG0773 | Mur_ligase, Mur_ligase_C, Mur_ligase_M | K01924 |
3NJ13 | Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) | ACIAD3517 | murG | UDP-N-acetylglucosamine:N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | COG0707 | Glyco_tran_28_C, Glyco_transf_28 | K02563 |
3NJMX | Nucleoside-specific channel-forming protein, Tsx | ACIAD3539 | conserved hypothetical protein | Channel_Tsx | |||
3NJT4 | Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain | ACIAD3575 | glmU | bifunctional protein [Includes: UDP-N-acetylglucosamine pyrophosphorylase (N-acetylglucosamine-1-phosphate uridyltransferase); Glucosamine-1-phosphate N-acetyltransferase ] | COG1207 | Hexapep, NTP_transf_3 | K04042 |
3NKBM | Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source | ACIAD3576 | glmS | glucosamine--fructose-6-phosphate aminotransferase | COG0449 | GATase_6, SIS | K00820 |
3NJK7 | Gram-negative-bacterium-type cell outer membrane assembly | ACIAD3586 | putative lipoprotein-34 precursor (NlpB) | ||||
3NKAS | Peptidase family M23 | ACIAD3607 | putative peptidase | COG0739 | Peptidase_M23 | K21472 | |
3NIFF | Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family | ACIAD3625 | putative RND efflux membrane fusion protein precursor | COG0845 | HlyD_D23 | K18302 | |
3NIZ7 | Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety | ACIAD3643 | fragment of conserved hypothetical protein (part 1) | ||||
3NIZ7 | Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety | ACIAD3644 | fragment of conserved hypothetical protein (part 2) | ||||
3NT4R | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides | ACIAD3647 | ppiA | peptidyl-prolyl cis-trans isomerase precursor (PPIase) (Rotamase) | COG0652 | Pro_isomerase | K03767 |
3NIM8 | Lytic murein transglycosylase | ACIAD3657 | putative membrane-bound lytic murein transglycosylase | PG_binding_1, SLT_2 | |||
3NJUJ | Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate | ACIAD3663 | mpl | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase | COG0773 | Mur_ligase, Mur_ligase_C, Mur_ligase_M | K02558 |
3NIES | Outer membrane efflux protein | ACIAD3675 | putative outer membrane protein | OEP |