NemeSys integrates:
- the complete genome sequence of a serogroup C clinical isolate (strain 8013),
- a library of mutants in ~1,000 of 8013's genes,
- 8 re-annotated Neisseria genomes: 5 N. meningitidis
(strains Z2491, MC58, FAM18, 053442 and alpha14), 2 N. gonorrhoeae (strains FA 1090 and NCCP11945)
and 1 N. lactamica (a ST-640 strain).
This webpage provides easy access to a database (NeisseriaScope) that allow users to:
- view each genome simultaneously with the synteny maps of other genomes in our database,
- access the results of the bioinformatic methods that were instrumental for manual annotation of each gene,
- determine for any gene whether it has been disrupted in the library of mutants, in which mutant(s), how many times and in
which position(s),
- perform queries using BLAST or keywords and export the results in various file formats (EMBL, GenBank, tab-delimited files
that can be easily browsed in Excel) etc.
Publication:
- NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis.
Genome Biology 2009, 10:R110
For further queries or to request a mutant please contact
Dr. Vladimir Pelicic.
| Query transposon insertion mutants of strain 8013: |
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| Explore Neisseria genomes: |
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