BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 81769affa3681b07f8a95c24770fc098.SwissProt.fasta
15 sequences; 6,831 total letters
Query= ACIAD3668
Length=441
Score E
Sequences producing significant alignments: (Bits) Value
P76641 Guanine deaminase [Escherichia coli (strain K12)] 572 0.0
Q9RYX4 Probable guanine deaminase [Deinococcus radiodurans (strai... 286 8e-96
Q86AW9 Guanine deaminase [Dictyostelium discoideum] 253 1e-82
Q9R111 Guanine deaminase [Mus musculus] 229 1e-73
Q07729 Probable guanine deaminase [Saccharomyces cerevisiae (stra... 227 2e-72
Q9WTT6 Guanine deaminase [Rattus norvegicus] 225 4e-72
Q5RAV9 Guanine deaminase [Pongo abelii] 219 8e-70
Q9Y2T3 Guanine deaminase [Homo sapiens] 218 2e-69
Q9VMY9 Guanine deaminase [Drosophila melanogaster] 217 4e-69
O14057 Probable guanine deaminase [Schizosaccharomyces pombe (str... 202 1e-62
Q58936 5'-deoxyadenosine deaminase [Methanocaldococcus jannaschii... 118 2e-32
Q9EYU0 Melamine deaminase [Paracidovorax citrulli] 105 1e-27
Q9I6Z0 8-oxoguanine deaminase [Pseudomonas aeruginosa (strain ATC... 102 7e-27
P72156 Atrazine chlorohydrolase [Pseudomonas sp. (strain ADP)] 100 3e-26
Q9X034 5-methylthioadenosine/S-adenosylhomocysteine deaminase [Th... 78.2 7e-19
>P76641 Guanine deaminase [Escherichia coli (strain K12)]
Length=439
Score = 572 bits (1474), Expect = 0.0
Identities = 268/429 (62%), Positives = 343/429 (80%), Gaps = 0/429 (0%)
Query 12 IRGRFLDIQSLVSQADQISQQVRYFEDGLMIVEQGKIRQFGHWDELNQHLSDTDIIEHYP 71
+RG F+D+ + ++I+ +R+ EDGL++++QGK+ FG W+ + DT + Y
Sbjct 11 VRGSFIDVTRTIDNPEEIASALRFIEDGLLLIKQGKVEWFGEWENGKHQIPDTIRVRDYR 70
Query 72 EQLIIPGFIDTHIHYPQTEMVGAYGEQLLSWLNTYTFPTELQFKNPHYAKGIADFFVQEL 131
+LI+PGF+DTHIHYPQ+EMVGAYGEQLL WLN +TFPTE ++++ YA+ ++ FF+++L
Sbjct 71 GKLIVPGFVDTHIHYPQSEMVGAYGEQLLEWLNKHTFPTERRYEDLEYAREMSAFFIKQL 130
Query 132 LKNGTTTALVFCTVHPESVDALFEAAEALQMRLIAGKVLMDRHAPEGLCDTAERAYEESK 191
L+NGTTTALVF TVHP+SVDALFEAA + MR+IAGKV+MDR+AP+ L DTAE +Y +SK
Sbjct 131 LRNGTTTALVFGTVHPQSVDALFEAASHINMRMIAGKVMMDRNAPDYLLDTAESSYHQSK 190
Query 192 TLIEKWHGKGRALYAITPRFAPTSTPEQLEKAGQLKQEYPDVYVHTHLSENKDEIAWVKD 251
LIE+WH GR LYAITPRFAPTS+PEQ+ A +LK+EYPD +VHTHL ENKDEIAWVK
Sbjct 191 ELIERWHKNGRLLYAITPRFAPTSSPEQMAMAQRLKEEYPDTWVHTHLCENKDEIAWVKS 250
Query 252 LFPQQKGYLDVYHHHGLTGKRSVFAHCVHLEEDEWQCMHQTDSAIAFCPTSNLFLGSGLF 311
L+P GYLDVYH +GLTGK VFAHCVHLEE EW + +T S+IAFCPTSNL+LGSGLF
Sbjct 251 LYPDHDGYLDVYHQYGLTGKNCVFAHCVHLEEKEWDRLSETKSSIAFCPTSNLYLGSGLF 310
Query 312 PLKKTWEKQVKVGLGTDIGAGTSFSLLQTVNEAYKVQQLQGDKLSAYESFYHATLGAAKA 371
LKK W+K+VKVG+GTDIGAGT+F++LQT+NEAYKV QLQG +LSAYE+FY ATLG AK+
Sbjct 311 NLKKAWQKKVKVGMGTDIGAGTTFNMLQTLNEAYKVLQLQGYRLSAYEAFYLATLGGAKS 370
Query 372 LDLDDKLGNFNIGKEADFVVLDLKATLLQRLRQSKSKSLEDALFALFTMGDDRNVEATYV 431
L LDD +GNF GKEADFVV++ AT LQ+LR S SL D LF + T+GDDR++ TYV
Sbjct 371 LGLDDLIGNFLPGKEADFVVMEPTATPLQQLRYDNSVSLVDKLFVMMTLGDDRSIYRTYV 430
Query 432 YGQKVYQKD 440
G+ VY+++
Sbjct 431 DGRLVYERN 439
>Q9RYX4 Probable guanine deaminase [Deinococcus radiodurans (strain
ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG
4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1)]
Length=439
Score = 286 bits (732), Expect = 8e-96
Identities = 170/420 (40%), Positives = 242/420 (58%), Gaps = 9/420 (2%)
Query 29 ISQQVRYFEDGLMIV-EQGKIRQFGHWDELNQHLS----DTDIIEHYPEQLIIPGFIDTH 83
+ ++ F DG + V + G I G + E+ + D ++ + +++PGFIDTH
Sbjct 18 VPDALQTFSDGALAVGDTGTIAHLGTFTEVLAEVRAACPDAEVHD-LRGGVLLPGFIDTH 76
Query 84 IHYPQTEMVGAYGEQLLSWLNTYTFPTELQFKNPHYAKGIADFFVQELLKNGTTTALVFC 143
+HYPQ ++G G LL WL+ T P E + + YA+ IA F+ L +GTTTALVF
Sbjct 77 VHYPQVRVLGGLGMALLEWLDRNTLPEEARLADAAYARTIAGEFLHGLASHGTTTALVFG 136
Query 144 TVHPESVDALFEAAEALQMRLIAGKVLMDRHAPEGLCDTAERAYEESKTLIEKWHGKGRA 203
+ ++D F A A +R++AG+V+ DR L T ERAY E K LIE+WHG+GR+
Sbjct 137 SHFAGAMDEFFAEAAARGLRVVAGQVVSDRLLRPELHTTPERAYAEGKALIERWHGQGRS 196
Query 204 LYAITPRFAPTSTPEQLEKAGQLKQEYPDVYVHTHLSENKDEIAWVKDLFPQQKGYLDVY 263
LYA+TPRF+ +++ L+ L E+PDV +H++EN EI V+ LFP + YLD Y
Sbjct 197 LYAVTPRFSLSASEGILDACAALLTEFPDVRFTSHINENNQEIEVVRGLFPGARDYLDTY 256
Query 264 HHHGLTGKRSVFAHCVHLEEDEWQCMHQTDSAIAFCPTSNLFLGSGLFPLKKTWEKQVKV 323
GL RSVFAH VH E E + ++A CP SN LGSGLFPL++ V V
Sbjct 257 ERAGLVTPRSVFAHNVHPNERELGVLAAQRCSVAHCPCSNSALGSGLFPLRRHLAAGVHV 316
Query 324 GLGTDIGAGTSFSLLQTVNEAYKVQQLQGDK---LSAYESFYHATLGAAKALDLDDKLGN 380
LGTD+G GT FSLL+ +AY +QQL G++ LS Y ATL A+AL LD ++G+
Sbjct 317 ALGTDVGGGTGFSLLKEGLQAYFMQQLLGEEGAALSPAHLLYLATLAGAQALGLDGQVGD 376
Query 381 FNIGKEADFVVLDLKATLLQRLRQSKSKSLEDALFALFTMGDDRNVEATYVYGQKVYQKD 440
F GK+ D V L +A + ++S E L ALF +G +VE +V G V+ ++
Sbjct 377 FTPGKQFDAVWLRPRAGSTLATVLAHAESEERTLAALFALGTGDDVERVWVGGGVVFARE 436
>Q86AW9 Guanine deaminase [Dictyostelium discoideum]
Length=450
Score = 253 bits (645), Expect = 1e-82
Identities = 137/373 (37%), Positives = 206/373 (55%), Gaps = 11/373 (3%)
Query 73 QLIIPGFIDTHIHYPQTEMVGAYGE-QLLSWLNTYTFPTELQFKNPHYAKGIADFFVQEL 131
+ +IPGFIDTH H PQ G + LL WL YTFP E +FK+ +A+ + V +
Sbjct 78 KFLIPGFIDTHAHAPQYHNAGTGTDLPLLKWLEKYTFPVESKFKDLIFAENVYGKVVDRM 137
Query 132 LKNGTTTALVFCTVHPESVDALFEAAEALQMRLIAGKVLMDRHAPEGLCDTAERAYEESK 191
L++GTTT + T+H E+ + L E R GKV MDRH+P+ +T E++ +K
Sbjct 138 LRHGTTTCCYYATIHLEASELLAEIVSKRGQRAFIGKVCMDRHSPDHYVETTEQSISNTK 197
Query 192 TLIEKWHGKGRALYA--ITPRFAPTSTPEQLEKAGQLKQEYPDVYVHTHLSENKDEIAWV 249
+++ KG L +TPRFAP+ T E + G L E + +HLSENKDEI WV
Sbjct 198 EFVDRILAKGNPLVQPIVTPRFAPSCTDELMVALGNLSHE-KQTLIQSHLSENKDEIEWV 256
Query 250 KDLFPQQKGYLDVYHHHGLTGKRSVFAHCVHLEEDEWQCMHQTDSAIAFCPTSNLFLGSG 309
K L+P + Y VY H L +R++ AHCVHL ++E + + +AI+ CP SN L SG
Sbjct 257 KSLYPGIESYTHVYKHFNLLNERTIMAHCVHLSDEEIKLISTQQTAISHCPISNFTLSSG 316
Query 310 LFPLKKTWEKQVKVGLGTDIGAGTSFSLLQTVNEAYKVQQL------QGDKLSAYESFYH 363
++K E +K+GLG+DI G S+LQ + ++ K L+ E+FY
Sbjct 317 NLDVRKVLEANIKLGLGSDISGGYHPSILQVIRDSIKCSNSHFFNNGNHTPLTFEEAFYL 376
Query 364 ATLGAAKALDLDDKLGNFNIGKEADFVVLDLKATLLQRLRQSKSKSLEDALFALFTMGDD 423
AT+G +K ++LD ++GNF +GK+ D ++D ++L+D +GDD
Sbjct 377 ATVGGSKVVNLDHRIGNFIVGKDFDAQIID-PFVQNSPFDCFDGETLKDIFQKFIYLGDD 435
Query 424 RNVEATYVYGQKV 436
RN+ + Y+ G K+
Sbjct 436 RNLSSLYIKGNKI 448
>Q9R111 Guanine deaminase [Mus musculus]
Length=454
Score = 229 bits (584), Expect = 1e-73
Identities = 138/386 (36%), Positives = 214/386 (55%), Gaps = 16/386 (4%)
Query 65 DIIEHYPEQLIIPGFIDTHIHYPQTEMVGAYGE-QLLSWLNTYTFPTELQFKNPHYAKGI 123
+I E + +PG +DTHIH PQ G+ + LL WLN YTFPTE +F++ A+ +
Sbjct 64 EIRELSHHEFFMPGLVDTHIHAPQYAFAGSNVDLPLLEWLNKYTFPTEQRFRSTDVAEEV 123
Query 124 ADFFVQELLKNGTTTALVFCTVHPESVDALFEAAEALQMRLIAGKVLMDRH--APEGLCD 181
V+ LKNGTTTA F T+H +S L E + R GKV MD + PE +
Sbjct 124 YTRVVRRTLKNGTTTACYFGTIHTDSSLILAEITDKFGQRAFVGKVCMDLNDTVPE-YKE 182
Query 182 TAERAYEESKTLIEKWHGKG--RALYAITPRFAPTSTPEQLEKAGQLKQEYPDVYVHTHL 239
T E + +E++ + + K R +TPRF + T + + G + + + D+Y+ +H+
Sbjct 183 TTEESVKETERFVSEMLQKNYPRVKPIVTPRFTLSCTETLMSELGNIAKTH-DLYIQSHI 241
Query 240 SENKDEIAWVKDLFPQQKGYLDVYHHHGLTGKRSVFAHCVHLEEDEWQCMHQTDSAIAFC 299
SEN++EI VK L+P K Y DVY + L ++V AH +L E+E + ++IA C
Sbjct 242 SENREEIEAVKSLYPSYKNYTDVYDKNNLLTNKTVMAHGCYLSEEELNIFSERGASIAHC 301
Query 300 PTSNLFLGSGLFPLKKTWEKQVKVGLGTDIGAGTSFSLLQTVNEAYKV------QQLQGD 353
P SNL L SGL + + + +VK+GLGTD+ G S+S+L + A V ++
Sbjct 302 PNSNLSLSSGLLNVLEVLKHKVKIGLGTDVAGGYSYSMLDAIRRAVMVSNVLLINKVNEK 361
Query 354 KLSAYESFYHATLGAAKALDLDDKLGNFNIGKEADFVVLDLKA--TLLQRLRQSKSKSLE 411
L+ E F ATLG ++AL LD ++GNF +GKE D ++++ +A + + +
Sbjct 362 NLTLKEVFRLATLGGSQALGLDSEIGNFEVGKEFDALLINPRASDSPIDLFYGDFVGDIS 421
Query 412 DALFALFT-MGDDRNVEATYVYGQKV 436
+A+ F +GDDRN+E YV G++V
Sbjct 422 EAVIQKFLYLGDDRNIEEVYVGGKQV 447
>Q07729 Probable guanine deaminase [Saccharomyces cerevisiae (strain
ATCC 204508 / S288c)]
Length=489
Score = 227 bits (579), Expect = 2e-72
Identities = 135/396 (34%), Positives = 213/396 (54%), Gaps = 35/396 (9%)
Query 77 PGFIDTHIHYPQTEMVGAYGEQ-LLSWLNTYTFPTELQFKNPHYAKGIADFFVQELLKNG 135
PGF+DTH H Q VG +G LL WL YTFP E N + A+ + + + + L +G
Sbjct 94 PGFVDTHNHVSQYPNVGVFGNSTLLDWLEKYTFPIEAALANENIAREVYNKVISKTLSHG 153
Query 136 TTTALVFCTVHPESVDALFEAAEALQMRLIAGKVLMDRHAPEGLCDTAERAYEESKTLIE 195
TTT + T+ +S L + + L R++ GKV MD + PE + + ++E + +++
Sbjct 154 TTTVAYYNTIDLKSTKLLAQLSSLLGQRVLVGKVCMDTNGPEYYIEDTKTSFESTVKVVK 213
Query 196 KWHGK---GRALYAITPRFAPTSTPEQLEKAGQLKQEYPDVYVHTHLSENKDEIAWVKDL 252
+TPRFAP+ + E +++ +L ++ +++V THLSENK+EI WV+DL
Sbjct 214 YIRETICDPLVNPIVTPRFAPSCSRELMQQLSKLVKD-ENIHVQTHLSENKEEIQWVQDL 272
Query 253 FPQQKGYLDVYHHHGLTGKRSVFAHCVHLEEDEWQCMHQTDSAIAFCPTSNLFLGSGLFP 312
FP+ + Y DVY +GL +++V AHC+HL + E + + Q I+ CP SN L SG
Sbjct 273 FPECESYTDVYDKYGLLTEKTVLAHCIHLTDAEARVIKQRRCGISHCPISNSSLTSGECR 332
Query 313 LKKTWEKQVKVGLGTDIGAGTSFSLLQTVNEAYKV------QQLQGDKLSAYESFYHATL 366
++ ++ +KVGLGTD+ AG S S+L T +A+ V ++ KLS E + AT+
Sbjct 333 VRWLLDQGIKVGLGTDVSAGHSCSILTTGRQAFAVSRHLAMRETDHAKLSVSECLFLATM 392
Query 367 GAAKALDLDDKLGNFNIGKEADFVVLDLKAT---------------LLQRLRQSKSK--- 408
G A+ L +D+ LG F++GK+ D ++D A +Q Q + +
Sbjct 393 GGAQVLRMDETLGTFDVGKQFDAQMIDTNAPGSNVDMFHWQLKEKDQMQEQEQEQGQDPY 452
Query 409 ------SLEDALFALFTMGDDRNVEATYVYGQKVYQ 438
+ ED + F GDDRN +V GQ+VYQ
Sbjct 453 KNPPLLTNEDIIAKWFFNGDDRNTTKVWVAGQQVYQ 488
>Q9WTT6 Guanine deaminase [Rattus norvegicus]
Length=454
Score = 225 bits (574), Expect = 4e-72
Identities = 137/386 (35%), Positives = 214/386 (55%), Gaps = 16/386 (4%)
Query 65 DIIEHYPEQLIIPGFIDTHIHYPQTEMVGAYGE-QLLSWLNTYTFPTELQFKNPHYAKGI 123
+I E + +PG +DTHIH PQ G+ + LL WLN YTFPTE +F++ A+ +
Sbjct 64 EIRELSHHEFFMPGLVDTHIHAPQYAFAGSNVDLPLLDWLNKYTFPTEKRFQSTDVAEEV 123
Query 124 ADFFVQELLKNGTTTALVFCTVHPESVDALFEAAEALQMRLIAGKVLMDRH--APEGLCD 181
V+ LKNGTTTA F T+H +S L E + R GKV MD + PE +
Sbjct 124 YTRVVRRTLKNGTTTACYFGTIHTDSSLILAEITDKFGQRAFVGKVCMDLNNTVPE-YKE 182
Query 182 TAERAYEESKTLIEKWHGKG--RALYAITPRFAPTSTPEQLEKAGQLKQEYPDVYVHTHL 239
T E + +E++ + + K R +TPRF+ + T + + G + + + D+Y+ +H+
Sbjct 183 TTEESVKETERFVSEMLQKNYSRVKPIVTPRFSLSCTETLMSELGNIAKTH-DLYIQSHI 241
Query 240 SENKDEIAWVKDLFPQQKGYLDVYHHHGLTGKRSVFAHCVHLEEDEWQCMHQTDSAIAFC 299
SEN++EI VK L+P K Y DVY + L ++V AH +L E+E + ++IA C
Sbjct 242 SENREEIEAVKSLYPGYKNYTDVYDKNNLLTNKTVMAHGCYLSEEELNVFSERGASIAHC 301
Query 300 PTSNLFLGSGLFPLKKTWEKQVKVGLGTDIGAGTSFSLLQTVNEAYKV------QQLQGD 353
P SNL L SGL + + +VK+GLGTD+ G S+S+L + A V ++
Sbjct 302 PNSNLSLSSGLLNVLDVLKHKVKIGLGTDVAGGYSYSMLDAIRRAVMVSNVLLINKVNEK 361
Query 354 KLSAYESFYHATLGAAKALDLDDKLGNFNIGKEADFVVLDLKA--TLLQRLRQSKSKSLE 411
L+ E F ATLG ++AL LD ++GNF +GK+ D ++++ +A + + +
Sbjct 362 SLTLKEVFRLATLGGSQALGLDREIGNFEVGKDFDALLINPRASDSPIDLFCGDFVGDIS 421
Query 412 DALFALFT-MGDDRNVEATYVYGQKV 436
+A+ F +GDDRN+E YV G++V
Sbjct 422 EAVIQKFLYLGDDRNIEEVYVGGKQV 447
>Q5RAV9 Guanine deaminase [Pongo abelii]
Length=454
Score = 219 bits (558), Expect = 8e-70
Identities = 133/385 (35%), Positives = 208/385 (54%), Gaps = 14/385 (4%)
Query 65 DIIEHYPEQLIIPGFIDTHIHYPQTEMVGAYGE-QLLSWLNTYTFPTELQFKNPHYAKGI 123
+I E + +PG +DTHIH Q G+ + LL WL YTFP E +F+N +A+ +
Sbjct 64 EIRELSHHEFFMPGLVDTHIHASQYSFAGSNIDLPLLEWLTKYTFPAEHRFQNTDFAEEV 123
Query 124 ADFFVQELLKNGTTTALVFCTVHPESVDALFEAAEALQMRLIAGKVLMDRHA--PEGLCD 181
V+ LKNGTTTA F T+H +S L + + R GKV M+ + PE
Sbjct 124 YTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMNLNDTFPEYNET 183
Query 182 TAERAYEESKTLIEKWHGK-GRALYAITPRFAPTSTPEQLEKAGQLKQEYPDVYVHTHLS 240
T E E + + E K R +TPRF+ + + + G + + + D+++ +H+S
Sbjct 184 TEESIKETERFVSEMLQRKYSRVKPIVTPRFSLSCSETLMGDLGNIAKTH-DLHIQSHIS 242
Query 241 ENKDEIAWVKDLFPQQKGYLDVYHHHGLTGKRSVFAHCVHLEEDEWQCMHQTDSAIAFCP 300
EN+DE+ VK+L+P K Y DVY + L ++V AH +L +E H+ ++IA CP
Sbjct 243 ENRDEVEAVKNLYPSYKNYTDVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCP 302
Query 301 TSNLFLGSGLFPLKKTWEKQVKVGLGTDIGAGTSFSLLQTVNEAYKV------QQLQGDK 354
SNL L SG + + + +VK+GLGTD+ G S+S+L + A V ++
Sbjct 303 NSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEKS 362
Query 355 LSAYESFYHATLGAAKALDLDDKLGNFNIGKEADFVVLDLKA--TLLQRLRQSKSKSLED 412
L+ E F ATLG ++AL LD ++GNF +GKE D ++++ KA + + + +
Sbjct 363 LTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDISE 422
Query 413 ALFALFT-MGDDRNVEATYVYGQKV 436
A+ F +GDDRN+E YV G++V
Sbjct 423 AVIQKFLYLGDDRNIEEVYVGGKQV 447
>Q9Y2T3 Guanine deaminase [Homo sapiens]
Length=454
Score = 218 bits (556), Expect = 2e-69
Identities = 132/386 (34%), Positives = 211/386 (55%), Gaps = 16/386 (4%)
Query 65 DIIEHYPEQLIIPGFIDTHIHYPQTEMVGAYGE-QLLSWLNTYTFPTELQFKNPHYAKGI 123
+I E + +PG +DTHIH Q G+ + LL WL YTFP E +F+N +A+ +
Sbjct 64 EIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFAEEV 123
Query 124 ADFFVQELLKNGTTTALVFCTVHPESVDALFEAAEALQMRLIAGKVLMDRHA--PEGLCD 181
V+ LKNGTTTA F T+H +S L + + R GKV MD + PE +
Sbjct 124 YTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPE-YKE 182
Query 182 TAERAYEESKTLIEKWHGKG--RALYAITPRFAPTSTPEQLEKAGQLKQEYPDVYVHTHL 239
T E + +E++ + + K R +TPRF+ + + + + G + + D+++ +H+
Sbjct 183 TTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTR-DLHIQSHI 241
Query 240 SENKDEIAWVKDLFPQQKGYLDVYHHHGLTGKRSVFAHCVHLEEDEWQCMHQTDSAIAFC 299
SEN+DE+ VK+L+P K Y VY + L ++V AH +L +E H+ ++IA C
Sbjct 242 SENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHC 301
Query 300 PTSNLFLGSGLFPLKKTWEKQVKVGLGTDIGAGTSFSLLQTVNEAYKV------QQLQGD 353
P SNL L SG + + + +VK+GLGTD+ G S+S+L + A V ++
Sbjct 302 PNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEK 361
Query 354 KLSAYESFYHATLGAAKALDLDDKLGNFNIGKEADFVVLDLKA--TLLQRLRQSKSKSLE 411
L+ E F ATLG ++AL LD ++GNF +GKE D ++++ KA + + +
Sbjct 362 SLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDIS 421
Query 412 DALFALFT-MGDDRNVEATYVYGQKV 436
+A+ F +GDDRN+E YV G++V
Sbjct 422 EAVIQKFLYLGDDRNIEEVYVGGKQV 447
>Q9VMY9 Guanine deaminase [Drosophila melanogaster]
Length=448
Score = 217 bits (553), Expect = 4e-69
Identities = 147/432 (34%), Positives = 215/432 (50%), Gaps = 36/432 (8%)
Query 36 FEDGLMIVEQ-GKIRQFGH----WDELNQ-HLSDTDIIEHYPEQLIIPGFIDTHIHYPQT 89
FE G + V+ GKI G W N H + Q ++PGF+D HIH PQ
Sbjct 21 FEGGFLAVDDAGKIIGVGQDYHAWASSNPAHAKGLTEVHLSDYQFLMPGFVDCHIHAPQF 80
Query 90 EMVG-AYGEQLLSWLNTYTFPTELQFKNPHYAKGIADFFVQELLKNGTTTALVFCTVHPE 148
+G LL WLNTYTFP E +F N YA+ + V+ L+ GTT A F T H E
Sbjct 81 AQLGLGLDMPLLDWLNTYTFPLEAKFSNHQYAQQVYQGVVEATLRCGTTLASYFATNHLE 140
Query 149 SVDALFEAAEALQMRLIAGKVLMDRHAPEGLCDTAERAYEESKTLIE--KWHGKGRALYA 206
S L A R + GKV + ++PE +TAE + + +E + G +
Sbjct 141 STLTLAREAVRQGQRALIGKVCSNCNSPEFYVETAEESVSATLAFVEGVRKLGSPMVMPT 200
Query 207 ITPRFAPTSTPEQLEKAGQLKQEYPDVYVHTHLSENKDEIAWVKDLFPQQKGYLDVYHHH 266
ITPRFA + + E L+ G + + + D+++ +H+SEN +EI VK +F + Y Y
Sbjct 201 ITPRFALSCSKELLKSLGDIAKRF-DLHIQSHISENLEEIEMVKGIF--KTSYAGAYDEA 257
Query 267 GLTGKRSVFAHCVHLEEDEWQCMHQTDSAIAFCPTSNLFLGSGLFPLKKTWEKQVKVGLG 326
GL ++V AH VHLE+DE + ++A CPTSN L SGL +++ V VGLG
Sbjct 258 GLLTNKTVLAHGVHLEDDEVALLKVRGCSVAHCPTSNTMLSSGLCDVQRLVSGGVSVGLG 317
Query 327 TDIGAGTSFSLLQTVNEA---------YKVQQLQGDKLSAYESF-----------YHATL 366
TD+ G S S+ + A +K Q ++G +S + F Y ATL
Sbjct 318 TDVSGGNSVSIQDVLLRALDVSKHLDFFKKQNIRGTGVSKTQDFNYHQLKYKQALYLATL 377
Query 367 GAAKALDLDDKLGNFNIGKEADFVVLDLKATLLQRLRQSKSKSLEDALFALFTMGDDRNV 426
G AKAL LD GNF +GK+ D +++D+ R S + +E ++ G DRN+
Sbjct 378 GGAKALSLDHLTGNFALGKDFDALLVDVSVVDKPLRRLSVDELVEKFIYT----GSDRNI 433
Query 427 EATYVYGQKVYQ 438
+V G+++ Q
Sbjct 434 VEVFVAGKRIKQ 445
Score = 18.1 bits (35), Expect = 9.0
Identities = 7/19 (37%), Positives = 10/19 (53%), Gaps = 0/19 (0%)
Query 6 PIQKTVIRGRFLDIQSLVS 24
P T++ D+Q LVS
Sbjct 291 PTSNTMLSSGLCDVQRLVS 309
>O14057 Probable guanine deaminase [Schizosaccharomyces pombe
(strain 972 / ATCC 24843)]
Length=527
Score = 202 bits (514), Expect = 1e-62
Identities = 133/397 (34%), Positives = 203/397 (51%), Gaps = 16/397 (4%)
Query 55 DELNQH--LSDTDIIEHYPEQLIIPGFIDTHIHYPQTEMVG-AYGEQLLSWLNTYTFPTE 111
+E H L + I + P Q + PG IDTHIH PQ G LL WL YTFP E
Sbjct 49 EEAKSHHLLKEATIHKLKPLQFMFPGLIDTHIHAPQYPNSGIGIDVPLLQWLEKYTFPLE 108
Query 112 LQFKNPHYAKGIADFFVQELLKNGTTTALVFCTVHPESVDALFEAAEALQMRLIAGKVLM 171
+ A+ + V+ L NGTT A F T+H + L E + R GK M
Sbjct 109 SSLADLEEARQVYKRVVERTLSNGTTFASYFSTLHTPTSALLAEICYSYGQRAYIGKCNM 168
Query 172 DRHAPEGLCD-TAERAYEESKTLIEKWH----GKGRALYAITPRFAPTSTPEQLEKAGQL 226
+ +P+ C+ +AE + E ++ LI + ITPRFAP+ T + L G+L
Sbjct 169 NNLSPDHYCEKSAESSLEATRQLISYMSILDPKREMVTPIITPRFAPSCTEDLLSGCGEL 228
Query 227 KQEYPDVYVHTHLSENKDEIAWVKDLFPQQKGYLDVYHHHGLTGKRSVFAHCVHLEEDEW 286
+++ ++ + TH+SEN EI VK+LFP++K Y DVY ++ L +++ AH +HLE++E
Sbjct 229 AEKH-NLPIQTHISENTSEIELVKELFPERKSYADVYDYYKLLTPQTILAHAIHLEDEEI 287
Query 287 QCMHQTDSAIAFCPTSNLFLGSGLFPLKKTWEKQVKVGLGTDIGAGTSFSLLQTVNEA-- 344
+ + + S I+ CPTSN L SGL ++K + + VGLGTD+ G + S+L + A
Sbjct 288 ELLTKRSSGISHCPTSNSILASGLANVRKLLDSGINVGLGTDVSGGYAPSILIALRHAAM 347
Query 345 --YKVQQLQGD---KLSAYESFYHATLGAAKALDLDDKLGNFNIGKEADFVVLDLKATLL 399
+ + GD L E Y AT G A+ + D++G+F +GK D +++DL A
Sbjct 348 TSRSLSYVLGDPKVMLDLSELLYLATQGGAEVVSRGDQVGSFAVGKYWDALIVDLSAETH 407
Query 400 QRLRQSKSKSLEDALFALFTMGDDRNVEATYVYGQKV 436
+ + + L DDRN+ +V G+ V
Sbjct 408 SCVDIFERDTWPVMLSKWVFTSDDRNLAQVWVNGRLV 444
Score = 18.1 bits (35), Expect = 9.1
Identities = 6/11 (55%), Positives = 7/11 (64%), Gaps = 0/11 (0%)
Query 427 EATYVYGQKVY 437
E Y YGQ+ Y
Sbjct 152 EICYSYGQRAY 162
>Q58936 5'-deoxyadenosine deaminase [Methanocaldococcus jannaschii
(strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC
100440)]
Length=420
Score = 118 bits (295), Expect = 2e-32
Identities = 114/422 (27%), Positives = 196/422 (46%), Gaps = 50/422 (12%)
Query 41 MIVEQGKIRQFGHWDELNQHLSDTDIIEHYPEQLIIPGFIDTHIHYPQTEMVGAYGE-QL 99
+++E KI++ G + + + + +II+ ++ IPG I+TH H P T G + L
Sbjct 16 ILIEGNKIKKIG--EVKKEEIENAEIIDG-KNKIAIPGLINTHTHIPMTLFRGVADDLPL 72
Query 100 LSWLNTYTFPTELQFKNPHYAKGIADFFVQELLKNGTTTALVFCTVHPESVDALFEAAEA 159
+ WLN Y +P E + G + E++++GTTT F ++ ++ + +A +
Sbjct 73 MEWLNNYIWPMEAKLNEEIVYWGTLLGCI-EMIRSGTTT---FNDMY-FFLEGIAKAVDE 127
Query 160 LQMRLIAGKVLMDRHAPEGLCDTAERAYEESKTLIEKWHG--KGRALYAITPRFAPTSTP 217
MR + ++D E ER + ++ I + R + A+ P T +
Sbjct 128 SGMRAVLAYGMIDLFDEE----RRERELKNAEKYINYINSLNNSRIMPALGPHAPYTCSK 183
Query 218 EQLEKAGQLKQEYPDVYVHTHLSENKDEIAWVKD-------LFPQQKGYLDVYHHHGLTG 270
E L + L ++Y +V +H HL+E DEI VK+ ++ G+ D
Sbjct 184 ELLMEVNNLAKKY-NVPIHIHLNETLDEIKMVKEKTGMEPFIYLNSFGFFD--------D 234
Query 271 KRSVFAHCVHLEEDEWQCMHQTDSAIAFCPTSNLFLGSGLFPLKKTWEKQVKVGLGTD-I 329
R++ AHCVHL ++E + M Q + ++ P SNL L SG+ P+ K + + V LGTD
Sbjct 235 VRAIAAHCVHLTDEEIKIMKQKNINVSHNPISNLKLASGVAPIPKLLAEGINVTLGTDGC 294
Query 330 GAGTSFSLLQTVNEA---YKVQQLQGDKLSAYESFYHATLGAAKALDLDDKLGNFNIGKE 386
G+ + +L + + + +K L + A E+F AT AKAL++ K G G
Sbjct 295 GSNNNLNLFEEIKVSAILHKGVNLNPTVVKAEEAFNFATKNGAKALNI--KAGEIREGYL 352
Query 387 ADFVVLDLKATLLQRLRQSKSKSLEDALFALFTMGDD---------RNVEATYVYGQKVY 437
AD V+++L L K + ++A DD R+ E V +KVY
Sbjct 353 ADIVLINLDKPYL----YPKENIMSHLVYAFNGFVDDVIIDGNIVMRDGEILTVDEEKVY 408
Query 438 QK 439
+K
Sbjct 409 EK 410
>Q9EYU0 Melamine deaminase [Paracidovorax citrulli]
Length=474
Score = 105 bits (261), Expect = 1e-27
Identities = 94/396 (24%), Positives = 181/396 (46%), Gaps = 40/396 (10%)
Query 29 ISQQVRYFEDGLMIVEQGKIRQFGHWDELNQHLSDTDIIEHYPEQLIIPGFIDTHIHYPQ 88
+ Q R D + V+ G+I G E +D I ++++PGFI+ H H Q
Sbjct 14 MDQYRRVLGDSWVHVQDGRIVALGVHAESVPPPADRVIDAR--GKVVLPGFINAHTHVNQ 71
Query 89 TEMVG--AYGEQLLSWLNTYTFPTELQFKNPHYAKGIADFFVQELLKNGTTTAL--VFCT 144
+ G ++G QL WL +P + + A + + E +++G TT
Sbjct 72 ILLRGGPSHGRQLYDWLFNVLYPGQKAMRPEDVAVAVR-LYCAEAVRSGITTINDNADSA 130
Query 145 VHPESVDALFEAAEALQMRLIAGKVLMDR--------------HAPE-GLCDTAER---A 186
++P +++A + +R++ ++ DR +P+ LC E A
Sbjct 131 IYPGNIEAAMAVYGEVGVRVVYARMFFDRMDGRIQGYVDALKARSPQVELCSIMEETAVA 190
Query 187 YEESKTLIEKWHGK--GRALYAITPRFAPTSTPEQLEKAGQLKQEYPDVY-VHTHLSENK 243
+ L +++HG GR P P T E + A ++ ++ +H S++
Sbjct 191 KDRITALSDQYHGTAGGRISVWPAPAITPAVTVEGMRWAQAFARDRAVMWTLHMAESDHD 250
Query 244 DEIAWVKDLFPQQKGYLDVYHHHGLTGKRSVFAHCVHLEEDEWQCMHQTDSAIAFCPTSN 303
+ + W+ P + Y++ Y GL +R AHCV+ + + + +H+ + +A SN
Sbjct 251 ERLHWMS---PAE--YMECY---GLLDERLQVAHCVYFDRKDVRLLHRHNVKVASQVVSN 302
Query 304 LFLGSGLFPLKKTWEKQVKVGLGTDIG-AGTSFSL---LQTVNEAYKVQQLQGDKLSAYE 359
+LGSG+ P+ + E+ + VG+GTD G S ++ ++ + ++ D L+ +
Sbjct 303 AYLGSGVAPVPEMVERGMAVGIGTDDGNCNDSVNMIGDMKFMAHIHRAVHRDADVLTPEK 362
Query 360 SFYHATLGAAKALDLDDKLGNFNIGKEADFVVLDLK 395
AT+ A++L +D ++G+ GK AD ++LDL+
Sbjct 363 ILEMATIDGARSLGMDHEIGSIETGKRADLILLDLR 398
>Q9I6Z0 8-oxoguanine deaminase [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228
/ 1C / PRS 101 / PAO1)]
Length=449
Score = 102 bits (254), Expect = 7e-27
Identities = 114/410 (28%), Positives = 182/410 (44%), Gaps = 45/410 (11%)
Query 39 GLMIVEQGKIRQF-GHWDELNQHL-SDTDIIEHYPEQLIIPGFIDTHIHYPQT---EMVG 93
G ++VE G+I + G + Q S D H +++PG ++TH H+ QT
Sbjct 22 GGLVVEDGRIVELLGAGQQPAQPCASQFDASRH----VVLPGLVNTHHHFYQTLTRAWAP 77
Query 94 AYGEQLLSWLNT-YTFPTELQFKNPHYAKGIADFFVQELLKNGTTTALVFCTVHP----E 148
+ L WL T Y L + A +A + ELL +G TTA + P +
Sbjct 78 VVNQPLFPWLKTLYPVWARLTPEKLELATKVA---LAELLLSGCTTAADHHYLFPGGLEQ 134
Query 149 SVDALFEAAEALQMR--LIAGKVLMDRH----APEGLCDTAERAYEESKTLIEKWHGKG- 201
++D E L MR L G + + P+ AE +S+ LI ++H +G
Sbjct 135 AIDVQAGVVEELGMRAMLTRGSMSLGEKDGGLPPQQTVQEAETILADSERLIARYHQRGD 194
Query 202 --RALYAITPRFAPTSTPEQLEKAGQLKQEYPDVYVHTHLSENKDEIAWVKDLFPQQKGY 259
R A+ P + TPE + + ++ + DV +HTHL+E DE +D Q+ G
Sbjct 195 GARVQIALAPCSPFSVTPEIMRASAEVAARH-DVRLHTHLAETLDE----EDFCLQRFGL 249
Query 260 --LDVYHHHGLTGKRSVFAHCVHLEEDEWQCMHQTDSAIAFCPTSNLFLGSGLFPLKKTW 317
+D G G R+ AH +H +E + + + + I CP+SN+ L SG+ P +
Sbjct 250 RTVDYLDSVGWLGPRTWLAHGIHFNAEEIRRLGEAGTGICHCPSSNMRLASGICPTVELE 309
Query 318 EKQVKVGLGTDIGAGTSFS-LLQTVNEAYKVQQLQ--GDKLSAYESFYHATLGAAKALDL 374
+GLG D A S ++ +A +Q+L+ ++++ + AT G+A+ L
Sbjct 310 AAGAPIGLGVDGSASNDASNMILEARQALYLQRLRYGAERITPELALGWATRGSARLLGR 369
Query 375 DDKLGNFNIGKEADFVVLDLKATLLQRLRQSKSKSLEDALFALFTMGDDR 424
D +G GK+AD + L LR S S D L AL DR
Sbjct 370 SD-IGELAPGKQADLALFK-----LDELRFSGS---HDPLSALLLCAADR 410
>P72156 Atrazine chlorohydrolase [Pseudomonas sp. (strain ADP)]
Length=474
Score = 100 bits (250), Expect = 3e-26
Identities = 92/395 (23%), Positives = 182/395 (46%), Gaps = 38/395 (10%)
Query 29 ISQQVRYFEDGLMIVEQGKIRQFGHWDELNQHLSDTDIIEHYPEQLIIPGFIDTHIHYPQ 88
+ Q R D + V+ G+I G E +D I ++++PGFI+ H H Q
Sbjct 14 MDQYRRVLGDSWVHVQDGRIVALGVHAESVPPPADRVIDAR--GKVVLPGFINAHTHVNQ 71
Query 89 TEMVG--AYGEQLLSWLNTYTFPTELQFKNPHYAKGIADFFVQELLKNGTTTAL--VFCT 144
+ G ++G Q WL +P + + A + + E +++G TT
Sbjct 72 ILLRGGPSHGRQFYDWLFNVVYPGQKAMRPEDVAVAVR-LYCAEAVRSGITTINENADSA 130
Query 145 VHPESVDALFEAAEALQMRLIAGKVLMDR--------------HAPE-GLCDTAER---A 186
++P +++A + +R++ ++ DR +P+ LC E A
Sbjct 131 IYPGNIEAAMAVYGEVGVRVVYARMFFDRMDGRIQGYVDALKARSPQVELCSIMEETAVA 190
Query 187 YEESKTLIEKWHGKGRALYAITPRFAPTS--TPEQLEKAGQLKQEYPDVYVHTHLSENKD 244
+ L +++HG ++ P A T+ T E + A ++ ++ H++E+ D
Sbjct 191 KDRITALSDQYHGTAGGRISVWPAPATTTAVTVEGMRWAQAFARDRAVMWT-LHMAES-D 248
Query 245 EIAWVKDLFPQQKGYLDVYHHHGLTGKRSVFAHCVHLEEDEWQCMHQTDSAIAFCPTSNL 304
+ + P + Y++ Y GL +R AHCV+ + + + +H+ + +A SN
Sbjct 249 HDERIHGMSPAE--YMECY---GLLDERLQVAHCVYFDRKDVRLLHRHNVKVASQVVSNA 303
Query 305 FLGSGLFPLKKTWEKQVKVGLGTDIG-AGTSFSL---LQTVNEAYKVQQLQGDKLSAYES 360
+LGSG+ P+ + E+ + VG+GTD G + S ++ ++ + ++ D L+ +
Sbjct 304 YLGSGVAPVPEMVERGMAVGIGTDNGNSNDSVNMIGDMKFMAHIHRAVHRDADVLTPEKI 363
Query 361 FYHATLGAAKALDLDDKLGNFNIGKEADFVVLDLK 395
AT+ A++L +D ++G+ GK AD ++LDL+
Sbjct 364 LEMATIDGARSLGMDHEIGSIETGKRADLILLDLR 398
>Q9X034 5-methylthioadenosine/S-adenosylhomocysteine deaminase
[Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099
/ NBRC 100826 / MSB8)]
Length=406
Score = 78.2 bits (191), Expect = 7e-19
Identities = 85/328 (26%), Positives = 139/328 (42%), Gaps = 33/328 (10%)
Query 73 QLIIPGFIDTHIHYPQTEMVGAYGE-QLLSWLNTYTFPTE--LQFKNPHYAKGIADFFVQ 129
+L++P +TH H P T + G + WL + P E L K +Y +A
Sbjct 45 KLVMPALFNTHTHAPMTLLRGVAEDLSFEEWLFSKVLPIEDRLTEKMAYYGTILAQM--- 101
Query 130 ELLKNGTTTALVFCTVHPESVDALFEAAEALQMRLIAGKVLMDRHAPEGLCDTAERAYEE 189
E+ ++G V H E + +A MR + + L+D + +G EE
Sbjct 102 EMARHGIA-GFVDMYFHEEWIA---KAVRDFGMRALLTRGLVDSNGDDG------GRLEE 151
Query 190 SKTLIEKWHG-KGRALYAITPRFAPTSTPEQLEKAGQLKQEYPDVYVHTHLSENKDEIAW 248
+ L +W+G +GR P + E L++ + + V HL E E
Sbjct 152 NLKLYNEWNGFEGRIFVGFGPHSPYLCSEEYLKRVFDTAKSL-NAPVTIHLYETSKEEYD 210
Query 249 VKDLFPQQKGYLDVYHHHGLTGKRSVFAHCVHLEEDEWQCMHQTDSAIAFCPTSNLFLGS 308
++D+ + GL +++ AHCVHL E + + ++ P SNL LG+
Sbjct 211 LEDIL-----------NIGLKEVKTIAAHCVHLPERYFGVLKDIPFFVSHNPASNLKLGN 259
Query 309 GLFPLKKTWEKQVKVGLGTD-IGAGTSFSLLQTVNEAYKVQQLQGDK-LSAYESFYHATL 366
G+ P+++ E +KV LGTD + S +L + A +Q+ Q + L T
Sbjct 260 GIAPVQRMIEHGMKVTLGTDGAASNNSLNLFFEMRLASLLQKAQNPRNLDVNTCLKMVTY 319
Query 367 GAAKALDLDDKLGNFNIGKEADFVVLDL 394
A+A+ K G G AD VV+DL
Sbjct 320 DGAQAMGF--KSGKIEEGWNADLVVIDL 345
Lambda K H a alpha
0.321 0.136 0.409 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 2365740
Database: 81769affa3681b07f8a95c24770fc098.SwissProt.fasta
Posted date: May 20, 2024 8:43 PM
Number of letters in database: 6,831
Number of sequences in database: 15
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
