BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: a2860ae1153c68f63a49acd26782ccf6.SwissProt.fasta
17 sequences; 2,425 total letters
Query= ACIAD3538
Length=108
Score E
Sequences producing significant alignments: (Bits) Value
Q8ZQ52 5-hydroxyisourate hydrolase [Salmonella typhimurium (strai... 95.1 3e-30
Q8Z7Q6 5-hydroxyisourate hydrolase [Salmonella typhi] 95.1 3e-30
Q4VYA5 5-hydroxyisourate hydrolase [Salmonella dublin] 95.1 3e-30
Q9A545 5-hydroxyisourate hydrolase [Caulobacter vibrioides (strai... 85.5 1e-26
Q8XB75 5-hydroxyisourate hydrolase [Escherichia coli O157:H7] 84.7 4e-26
P76341 5-hydroxyisourate hydrolase [Escherichia coli (strain K12)] 84.7 4e-26
Q9KET9 5-hydroxyisourate hydrolase [Halalkalibacterium halodurans... 80.5 1e-24
Q21882 Probable 5-hydroxyisourate hydrolase R09H10.3 [Caenorhabdi... 80.5 2e-24
Q9I3J5 5-hydroxyisourate hydrolase [Pseudomonas aeruginosa (strai... 79.0 6e-24
O32142 5-hydroxyisourate hydrolase [Bacillus subtilis (strain 168)] 78.2 8e-24
O44578 Probable 5-hydroxyisourate hydrolase ZK697.8 [Caenorhabdit... 78.6 1e-23
Q06S87 5-hydroxyisourate hydrolase [Danio rerio] 77.8 2e-23
Q8YFU1 5-hydroxyisourate hydrolase [Brucella melitensis biotype 1... 76.3 5e-23
Q9CRB3 5-hydroxyisourate hydrolase [Mus musculus] 67.4 1e-19
Q9LVM5 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylas... 65.9 1e-17
O55245 Transthyretin [Crocodylus porosus] 43.5 4e-10
P30623 Transthyretin [Tiliqua rugosa] 42.7 8e-10
>Q8ZQ52 5-hydroxyisourate hydrolase [Salmonella typhimurium (strain
LT2 / SGSC1412 / ATCC 700720)]
Length=136
Score = 95.1 bits (235), Expect = 3e-30
Identities = 52/110 (47%), Positives = 65/110 (59%), Gaps = 3/110 (3%)
Query 1 MISTHILDTHLGKPATQVDVRLYNAKTRDL--IGQGVTDQDGRIKNFGREDLEA-GAYLL 57
++S HILD GKPA V+V L K + G TDQDGRIK E A G Y +
Sbjct 27 ILSVHILDQQTGKPAPGVEVVLEQKKDNGWTQLNTGHTDQDGRIKALWPEKAAAPGDYRV 86
Query 58 EYDVAPYFSQKQLKTFFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
+ YF K+L TFFP++ ++F I EHYHVPLL+S + YSTYRGS
Sbjct 87 IFKTGQYFESKKLDTFFPEIPVEFHISKTNEHYHVPLLLSQYGYSTYRGS 136
>Q8Z7Q6 5-hydroxyisourate hydrolase [Salmonella typhi]
Length=136
Score = 95.1 bits (235), Expect = 3e-30
Identities = 52/110 (47%), Positives = 65/110 (59%), Gaps = 3/110 (3%)
Query 1 MISTHILDTHLGKPATQVDVRLYNAKTRDL--IGQGVTDQDGRIKNFGREDLEA-GAYLL 57
++S HILD GKPA V+V L K + G TDQDGRIK E A G Y +
Sbjct 27 ILSVHILDQQTGKPAPGVEVVLEQKKDNGWTQLNTGHTDQDGRIKALWPEKAAAPGDYRV 86
Query 58 EYDVAPYFSQKQLKTFFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
+ YF K+L TFFP++ ++F I EHYHVPLL+S + YSTYRGS
Sbjct 87 IFKTGQYFESKKLDTFFPEIPVEFHISKTNEHYHVPLLLSQYGYSTYRGS 136
>Q4VYA5 5-hydroxyisourate hydrolase [Salmonella dublin]
Length=136
Score = 95.1 bits (235), Expect = 3e-30
Identities = 52/110 (47%), Positives = 65/110 (59%), Gaps = 3/110 (3%)
Query 1 MISTHILDTHLGKPATQVDVRLYNAKTRDL--IGQGVTDQDGRIKNFGREDLEA-GAYLL 57
++S HILD GKPA V+V L K + G TDQDGRIK E A G Y +
Sbjct 27 ILSVHILDQQTGKPAPGVEVVLEQKKDNGWTQLNTGHTDQDGRIKALWPEKAAAPGDYRV 86
Query 58 EYDVAPYFSQKQLKTFFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
+ YF K+L TFFP++ ++F I EHYHVPLL+S + YSTYRGS
Sbjct 87 IFKTGQYFESKKLDTFFPEIPVEFHISKTNEHYHVPLLLSQYGYSTYRGS 136
>Q9A545 5-hydroxyisourate hydrolase [Caulobacter vibrioides (strain
ATCC 19089 / CB15)]
Length=115
Score = 85.5 bits (210), Expect = 1e-26
Identities = 47/112 (42%), Positives = 64/112 (57%), Gaps = 6/112 (5%)
Query 2 ISTHILDTHLGKPATQVDVRLY--NAKTRDLIGQGVTDQDGRIKNFGREDLEAGAYLLEY 59
++THILD GKPA V VR+ + + + + TD DGR + EDL G Y LE+
Sbjct 4 LTTHILDQASGKPAAGVGVRVSRRDGEQTQWLAELRTDADGRARLVAGEDLAVGGYRLEF 63
Query 60 DVAPYFSQKQLKT----FFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
+ +F L F V+I FA+ N +H+HVPLL+SP+ YSTYRGS
Sbjct 64 AIGDHFKASGLPVSDPPFLDVVVIDFAVSNLDQHWHVPLLVSPYGYSTYRGS 115
>Q8XB75 5-hydroxyisourate hydrolase [Escherichia coli O157:H7]
Length=137
Score = 84.7 bits (208), Expect = 4e-26
Identities = 45/110 (41%), Positives = 62/110 (56%), Gaps = 3/110 (3%)
Query 1 MISTHILDTHLGKPATQVDVRLYNAKTRDLI--GQGVTDQDGRIKNFGREDLEA-GAYLL 57
++S HIL+ GKPA V V L + TD+DGRIK E G Y +
Sbjct 28 ILSVHILNQQTGKPAADVTVTLEKKADNGWLQLNTAKTDKDGRIKALWPEQTATTGDYRV 87
Query 58 EYDVAPYFSQKQLKTFFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
+ YF ++ L++FFP++ ++F I EHYHVPLL+S + YSTYRGS
Sbjct 88 VFKTGDYFKKQNLESFFPEIPVEFHINKVNEHYHVPLLLSQYGYSTYRGS 137
>P76341 5-hydroxyisourate hydrolase [Escherichia coli (strain
K12)]
Length=137
Score = 84.7 bits (208), Expect = 4e-26
Identities = 45/110 (41%), Positives = 62/110 (56%), Gaps = 3/110 (3%)
Query 1 MISTHILDTHLGKPATQVDVRLYNAKTRDLI--GQGVTDQDGRIKNFGREDLEA-GAYLL 57
++S HIL+ GKPA V V L + TD+DGRIK E G Y +
Sbjct 28 ILSVHILNQQTGKPAADVTVTLEKKADNGWLQLNTAKTDKDGRIKALWPEQTATTGDYRV 87
Query 58 EYDVAPYFSQKQLKTFFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
+ YF ++ L++FFP++ ++F I EHYHVPLL+S + YSTYRGS
Sbjct 88 VFKTGDYFKKQNLESFFPEIPVEFHINKVNEHYHVPLLLSQYGYSTYRGS 137
>Q9KET9 5-hydroxyisourate hydrolase [Halalkalibacterium halodurans
(strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153
/ C-125)]
Length=119
Score = 80.5 bits (197), Expect = 1e-24
Identities = 45/115 (39%), Positives = 64/115 (56%), Gaps = 9/115 (8%)
Query 2 ISTHILDTHLGKPATQVDVRLYN---AKTRDLIGQGVTDQDGRIKN--FGREDLEAGAYL 56
++TH+LDT GKPA V V L+ +L+ + VT+QDGR+ + G Y
Sbjct 5 VTTHVLDTSCGKPAAGVVVELWRIVEGGESELLTKAVTNQDGRLDKPLLTENKMARGVYE 64
Query 57 LEYDVAPYFSQK----QLKTFFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
L + V YF + Q F + ++F +E+ EHYHVPLL++P YSTYRGS
Sbjct 65 LRFQVGDYFLRNGFVNQAYPFLHVIPVRFGLEDVNEHYHVPLLVAPGGYSTYRGS 119
>Q21882 Probable 5-hydroxyisourate hydrolase R09H10.3 [Caenorhabditis
elegans]
Length=135
Score = 80.5 bits (197), Expect = 2e-24
Identities = 44/109 (40%), Positives = 60/109 (55%), Gaps = 3/109 (3%)
Query 2 ISTHILDTHLGKPATQVDVRLYNAKTRDL--IGQGVTDQDGRIKNFGRE-DLEAGAYLLE 58
IS H+LD G PA V + Y + D IG T +GR+ + L G Y L
Sbjct 27 ISAHVLDISGGSPAGGVQILAYIQQNDDWTKIGSEFTQDNGRVDWVSPDFTLIPGTYRLV 86
Query 59 YDVAPYFSQKQLKTFFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
Y PY+ K +++F+P V + F I + +HYHVPL +SP+ YSTYRGS
Sbjct 87 YITEPYYKAKNVESFYPYVEVVFNIRDATQHYHVPLTLSPWGYSTYRGS 135
>Q9I3J5 5-hydroxyisourate hydrolase [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG
12228 / 1C / PRS 101 / PAO1)]
Length=126
Score = 79.0 bits (193), Expect = 6e-24
Identities = 42/114 (37%), Positives = 66/114 (58%), Gaps = 8/114 (7%)
Query 2 ISTHILDTHLGKPATQVDVRLYNAKTR--DLIGQGVTDQDGRIKN--FGREDLEAGAYLL 57
++TH+LD+ G P + + LY + + +LI +T+ DGR ED G Y L
Sbjct 13 LTTHVLDSAHGCPGHGIKIELYRVEGQQLELIATTLTNHDGRCDQPVLQGEDFRPGVYQL 72
Query 58 EYDVAPYFSQKQLK----TFFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
++ Y+ + ++ F QV+++F I + +HYHVPLLISP++YSTYRGS
Sbjct 73 VFNAGDYYRARGVQLPEPAFLDQVVLRFGIASADDHYHVPLLISPYSYSTYRGS 126
>O32142 5-hydroxyisourate hydrolase [Bacillus subtilis (strain
168)]
Length=114
Score = 78.2 bits (191), Expect = 8e-24
Identities = 41/112 (37%), Positives = 62/112 (55%), Gaps = 7/112 (6%)
Query 2 ISTHILDTHLGKPATQVDVRLYNAKTRDLIGQGVTDQDGRIKN--FGREDLEAGAYLLEY 59
++THILD GKPA V + L ++ + T+ DGR+ E+L +G Y++E+
Sbjct 4 LTTHILDLTCGKPAANVKIGLKRLG-ESIMKEVYTNNDGRVDVPLLAGEELMSGEYVMEF 62
Query 60 DVAPYFSQKQLKT----FFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
YF+ K + F V ++F + +P HYH+PLL+SPF Y YRGS
Sbjct 63 HAGDYFASKNMNAADQPFLTIVTVRFQLADPDAHYHIPLLLSPFGYQVYRGS 114
>O44578 Probable 5-hydroxyisourate hydrolase ZK697.8 [Caenorhabditis
elegans]
Length=136
Score = 78.6 bits (192), Expect = 1e-23
Identities = 44/111 (40%), Positives = 61/111 (55%), Gaps = 7/111 (6%)
Query 2 ISTHILDTHLGKPATQVDVRLY----NAKTRDLIGQGVTDQDGRIKNFGRE-DLEAGAYL 56
IS H+LD G PA + + + N T IG T +GR+ + L G Y
Sbjct 28 ISAHVLDISGGSPAGGIQILAFILLNNGWTN--IGSQFTQDNGRVDWVSPDFTLIPGTYR 85
Query 57 LEYDVAPYFSQKQLKTFFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
L Y PY++ K +++F+P V + F I N +HYHVPL +SP+ YSTYRGS
Sbjct 86 LVYITEPYYTAKNVESFYPYVEVVFNIRNATQHYHVPLTLSPWGYSTYRGS 136
>Q06S87 5-hydroxyisourate hydrolase [Danio rerio]
Length=138
Score = 77.8 bits (190), Expect = 2e-23
Identities = 40/111 (36%), Positives = 63/111 (57%), Gaps = 5/111 (5%)
Query 2 ISTHILDTHLGKPATQVDVRLYN----AKTRDLIGQGVTDQDGRIKNF-GREDLEAGAYL 56
+STH+L+ G P + + L+ + +++ G+T+ DGR +E+ AG Y
Sbjct 28 LSTHVLNIAQGVPGANMTIVLHRLDPVSSAWNILTTGITNDDGRCPGLITKENFIAGVYK 87
Query 57 LEYDVAPYFSQKQLKTFFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
+ ++ Y+ F+P V I F I N ++HYHVPLL+S F+YSTYRGS
Sbjct 88 MRFETGKYWDALGETCFYPYVEIVFTITNTSQHYHVPLLLSRFSYSTYRGS 138
>Q8YFU1 5-hydroxyisourate hydrolase [Brucella melitensis biotype
1 (strain 16M / ATCC 23456 / NCTC 10094)]
Length=118
Score = 76.3 bits (186), Expect = 5e-23
Identities = 45/115 (39%), Positives = 67/115 (58%), Gaps = 9/115 (8%)
Query 2 ISTHILDTHLGKPATQVDVRLYN---AKTRDLIGQGVTDQDGRIKN--FGREDLEAGAYL 56
+STH+LDT G PA + V LY + T +L+ + VT+ DGR +++ G Y
Sbjct 4 LSTHVLDTAHGTPAAAMRVELYRIAASGTPELLKRVVTNLDGRTDAPLLSGDEMRTGIYE 63
Query 57 LEYDVAPYFSQKQLKT----FFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
L++ VA YF + + F + I+F I + +YHVPLL+SP++YSTYRGS
Sbjct 64 LQFHVAEYFEGRGAELAHEPFLDLIPIRFGIADEDGNYHVPLLVSPWSYSTYRGS 118
>Q9CRB3 5-hydroxyisourate hydrolase [Mus musculus]
Length=118
Score = 67.4 bits (163), Expect = 1e-19
Identities = 37/111 (33%), Positives = 61/111 (55%), Gaps = 5/111 (5%)
Query 2 ISTHILDTHLGKPATQVDVRLYNAKTRDL----IGQGVTDQDGRIKNF-GREDLEAGAYL 56
++TH+LDT G PA + +RL + + T+ DGR ++ G Y
Sbjct 8 LTTHVLDTASGLPAQGLCLRLSRLEAPCQQWMELRTSYTNLDGRCPGLLTPSQIKPGTYK 67
Query 57 LEYDVAPYFSQKQLKTFFPQVLIQFAIENPAEHYHVPLLISPFAYSTYRGS 107
L +D Y+ ++ ++F+P V + F I + +HVPLL+SP++Y+TYRGS
Sbjct 68 LFFDTERYWKERGQESFYPYVEVVFTITKETQKFHVPLLLSPWSYTTYRGS 118
>Q9LVM5 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
/ 5-hydroxyisourate hydrolase [Arabidopsis thaliana]
Length=324
Score = 65.9 bits (159), Expect = 1e-17
Identities = 45/123 (37%), Positives = 61/123 (50%), Gaps = 21/123 (17%)
Query 2 ISTHILDTHLGKPATQVDVRL--YNAKTR-----------DLIGQGVTDQDGRIKNFGR- 47
I+TH+LD G PA V+V L ++ T +G TD+DGR
Sbjct 206 ITTHVLDVSRGAPAAGVEVHLEVWSGTTGPSFVHGGGGVWSSVGTSATDRDGRSGPLMDL 265
Query 48 -EDLEAGAYLLEYDVAPYFSQKQLKTFFPQVLIQFAIENPA--EHYHVPLLISPFAYSTY 104
+ L G Y + +D A Y FFP V I F + EH+HVPLL++PF++STY
Sbjct 266 VDALNPGTYRISFDTAKYSPG----CFFPYVSIVFQVTESQKWEHFHVPLLLAPFSFSTY 321
Query 105 RGS 107
RGS
Sbjct 322 RGS 324
>O55245 Transthyretin [Crocodylus porosus]
Length=150
Score = 43.5 bits (101), Expect = 4e-10
Identities = 32/104 (31%), Positives = 49/104 (47%), Gaps = 7/104 (7%)
Query 6 ILDTHLGKPATQVDVRLYNAKTRDLIGQ----GVTDQDGRIKNF-GREDLEAGAYLLEYD 60
+LD G PA V ++++ KT D Q G T + G + E G Y +E+D
Sbjct 39 VLDAVRGSPAANVAIKVFK-KTSDGDWQEFAAGKTTEFGEVHELTSDEKFVEGIYRVEFD 97
Query 61 VAPYFSQKQLKTFFPQVLIQF-AIENPAEHYHVPLLISPFAYST 103
+ Y+ L F + F A ++ HY + L+SPF+YST
Sbjct 98 TSSYWKALGLSPFHEYADVVFTANDSGHRHYTIAALLSPFSYST 141
>P30623 Transthyretin [Tiliqua rugosa]
Length=150
Score = 42.7 bits (99), Expect = 8e-10
Identities = 28/103 (27%), Positives = 46/103 (45%), Gaps = 5/103 (5%)
Query 6 ILDTHLGKPATQVDVRLYNAKTRD---LIGQGVTDQDGRIKNFGR-EDLEAGAYLLEYDV 61
+LD G+PAT + V++ G T++ G I E G Y +E+D
Sbjct 39 VLDAVRGRPATSIAVKVSKMSEEGDWKEFANGKTNEFGEIHELTTDEQFVQGLYKVEFDT 98
Query 62 APYFSQKQLKTFFPQVLIQFAIENPAE-HYHVPLLISPFAYST 103
+ Y+ + F + F+ + HY + L+SPF+YST
Sbjct 99 SSYWKALGVSPFHEYADVVFSANDSGHRHYTIAALLSPFSYST 141
Lambda K H a alpha
0.326 0.143 0.427 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 146146
Database: a2860ae1153c68f63a49acd26782ccf6.SwissProt.fasta
Posted date: May 13, 2024 8:22 PM
Number of letters in database: 2,425
Number of sequences in database: 17
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
Loading
Data ...
