BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 7a4dff882605ad93f8d0131d5e0b5888.SwissProt.fasta
14 sequences; 7,215 total letters
Query= ACIAD3506
Length=662
Score E
Sequences producing significant alignments: (Bits) Value
P10802 Dihydrolipoyllysine-residue acetyltransferase component of... 531 0.0
P06959 Dihydrolipoyllysine-residue acetyltransferase component of... 520 0.0
Q59638 Dihydrolipoyllysine-residue acetyltransferase component of... 484 3e-168
P45118 Dihydrolipoyllysine-residue acetyltransferase component of... 422 6e-144
Q59098 Dihydrolipoyllysine-residue acetyltransferase component of... 416 9e-142
P35489 Dihydrolipoyllysine-residue acetyltransferase component of... 285 2e-91
Q8NNJ2 Dihydrolipoyllysine-residue acetyltransferase component of... 286 3e-90
Q8K9T8 Dihydrolipoyllysine-residue acetyltransferase component of... 267 3e-86
P57302 Dihydrolipoyllysine-residue acetyltransferase component of... 259 3e-83
Q89AQ9 Dihydrolipoyllysine-residue acetyltransferase component of... 253 5e-81
P9WIS7 Dihydrolipoyllysine-residue acetyltransferase component of... 232 3e-71
P11961 Dihydrolipoyllysine-residue acetyltransferase component of... 227 7e-71
P21883 Dihydrolipoyllysine-residue acetyltransferase component of... 217 8e-67
Q59821 Dihydrolipoyllysine-residue acetyltransferase component of... 212 3e-65
>P10802 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Azotobacter vinelandii]
Length=638
Score = 531 bits (1369), Expect = 0.0
Identities = 311/670 (46%), Positives = 424/670 (63%), Gaps = 47/670 (7%)
Query 3 VKTPDIGVDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLGDE 62
++ PDIG D V E+LVK GD I L++LES KAS+EVPS +GVVKS+ V LGD+
Sbjct 5 IRVPDIGGD-GEVIELLVKTGDLIEVEQGLVVLESAKASMEVPSPKAGVVKSVSVKLGDK 63
Query 63 VSEGTTLIELESGDNTDKTESESAPAQTEVKAETPVEQV----APQETKPATSTSAASSV 118
+ EG +IELE + +APA+ P + V AP AT AA+S
Sbjct 64 LKEGDAIIELEPAAG-----AAAAPAEAAAVPAAPTQAVDEAEAPSPGASATPAPAAASQ 118
Query 119 VEVQVPDIG-VEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKA 177
EV+VPDIG KA V E+LV GD++ SL++LESDKAS+E+PS SG +ES+ ++
Sbjct 119 -EVRVPDIGSAGKARVIEVLVKAGDQVQAEQSLIVLESDKASMEIPSPASGVVESVAIQL 177
Query 178 GDTIQEGVLLLKVKTAGASN--AAPAKQEAVVPTAAPVATKAETQAETPAVQSAPAGAVD 235
+ G L+L ++T GA APA A P AP+A A AG +
Sbjct 178 NAEVGTGDLILTLRTTGAQAQPTAPAAAAAASPAPAPLAPAA-------------AGPQE 224
Query 236 VLVPDLG-VDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQ 294
V VPD+G KA V E+LV GD++ ++S++V+ESDKA++E+PS +G+V+++ V+
Sbjct 225 VKVPDIGSAGKARVIEVLVKAGDQVQAEQSLIVLESDKASMEIPSPAAGVVESVAVQLNA 284
Query 295 DVKEGILLVTVEAEGAVASAPKAPVAKAEAAPAPAAQKAEAPAAKVETAPQAGADKLTKE 354
+V G ++T+ GA S P+A + +AA AP A A AP AP
Sbjct 285 EVGTGDQILTLRVAGAAPSGPRARGSPGQAAAAPGAAPAPAPVG----APSRNG------ 334
Query 355 QEAENSKVYAGPAVRKLARELGVVLAQVKASGEHGRLMKEDIYAYVKQRLTAPVAAPKAA 414
+KV+AGPAVR+LARE GV LA + ++G GR++KED+ AYVK + AP AA
Sbjct 335 -----AKVHAGPAVRQLAREFGVELAAINSTGPRGRILKEDVQAYVKAMMQKAKEAP-AA 388
Query 415 AAAVASGLPTLP--DFSAFGGVEEKTLTRLQQVSIPQLSLNNF-IPQVTQFDLADITELE 471
AA +G+P +P DF+ +G +EE +TRL Q+ L + +P VTQF+ ADITELE
Sbjct 389 GAASGAGIPPIPPVDFAKYGEIEEVPMTRLMQIGATNLHRSWLNVPHVTQFESADITELE 448
Query 472 AWRNDLKGNFKKEGISLTIMAFIIKAVAHLLKEEREFAGHLSDDGKSVLLRKEIHMGIAV 531
A+R K +K G+ LT++ ++KA A+LLKE +F L+ G++++ +K +H+G AV
Sbjct 449 AFRVAQKAVAEKAGVKLTVLPLLLKACAYLLKELPDFNSSLAPSGQALIRKKYVHIGFAV 508
Query 532 ATPDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQGANFTISSLGAIGGTA 591
TPDGL VPV+RN DQK++ Q+A E + +KAR KKL +QGA FTISSLG IGGTA
Sbjct 509 DTPDGLLVPVIRNVDQKSLLQLAAEAAELAEKARSKKLGADAMQGACFTISSLGHIGGTA 568
Query 592 FTPLVNWPQVAILGISPATMQPVWNGKDFDPRLMLPLSLSYDHRVINGADAARFTNKLTK 651
FTP+VN P+VAILG+S A+MQPVW+GK F PRLMLPLSLSYDHRVINGA AARFT +L
Sbjct 569 FTPIVNAPEVAILGVSKASMQPVWDGKAFQPRLMLPLSLSYDHRVINGAAAARFTKRLGD 628
Query 652 LLQDIRSLLI 661
LL DIR++L+
Sbjct 629 LLADIRAILL 638
Score = 77.4 bits (189), Expect = 6e-18
Identities = 53/137 (39%), Positives = 70/137 (51%), Gaps = 8/137 (6%)
Query 2 QVKTPDIG-VDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLG 60
+VK PDIG KA V E+LVK GD + SLI+LESDKAS+E+PS A+GVV+S+ V L
Sbjct 224 EVKVPDIGSAGKARVIEVLVKAGDQVQAEQSLIVLESDKASMEIPSPAAGVVESVAVQLN 283
Query 61 DEVSEGTTLIELE-SGDNTDKTESESAPAQTEVKAETPVEQVAPQETKPATSTSA---AS 116
EV G ++ L +G + +P Q A P AP + A A
Sbjct 284 AEVGTGDQILTLRVAGAAPSGPRARGSPGQA---AAAPGAAPAPAPVGAPSRNGAKVHAG 340
Query 117 SVVEVQVPDIGVEKATV 133
V + GVE A +
Sbjct 341 PAVRQLAREFGVELAAI 357
>P06959 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Escherichia coli (strain
K12)]
Length=630
Score = 520 bits (1338), Expect = 0.0
Identities = 303/667 (45%), Positives = 424/667 (64%), Gaps = 45/667 (7%)
Query 1 MQVKTPDIGVDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLG 60
+++K PDIG D+ + EILVKVGD + SLI +E DKAS+EVPS +G+VK I VS+G
Sbjct 3 IEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVSVG 62
Query 61 DEVSEGTTLIELESGDNTDKTESESAPAQTEVKAETPVEQVAPQETKPATSTSAASSVVE 120
D+ G ++ +S D +++APAQ E K +E PA + +AA++ +
Sbjct 63 DKTQTGALIMIFDSADGA----ADAAPAQAEEK----------KEAAPAAAPAAAAAK-D 107
Query 121 VQVPDIGVEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAGDT 180
V VPDIG ++ V E+LV VGD++ SL+ +E DKAS+EVP+ +GT++ I+V GD
Sbjct 108 VNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEIKVNVGDK 167
Query 181 IQEGVLLLKVKTAG-ASNAAPAKQEAVVPTAAPVATKAETQAETPAVQSAPAGAVDVLVP 239
+ G L++ + AG A AAPA ++ P AAP PA AG +V VP
Sbjct 168 VSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAAPA----------PA-----AGVKEVNVP 212
Query 240 DLGVDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQDVKEG 299
D+G D+ V E++V VGDK+ ++S++ VE DKA++EVP+ +G+VK + V G VK G
Sbjct 213 DIGGDEVEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTG 272
Query 300 ILLVTVEAEGAVASAPKAPVAKAEAAPAPAAQKAEAPAAKVETAPQAGADKLTKEQEAEN 359
L++ E EGA +A AP + AAPAPAA KAEAPAA AP A A+ K + AEN
Sbjct 273 SLIMIFEVEGAAPAA--APAKQEAAAPAPAA-KAEAPAA----APAAKAEG--KSEFAEN 323
Query 360 SK-VYAGPAVRKLARELGVVLAQVKASGEHGRLMKEDIYAYVKQRLTAPVAAPKAAAAAV 418
V+A P +R+LARE GV LA+VK +G GR+++ED+ AYVK+ + AAP A +
Sbjct 324 DAYVHATPLIRRLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGI 383
Query 419 ASGLP-TLPDFSAFGGVEEKTLTRLQQVSIPQLSLN-NFIPQVTQFDLADITELEAWRND 476
LP DFS FG +EE L R+Q++S LS N IP VT FD DITELEA+R
Sbjct 384 PGMLPWPKVDFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQ 443
Query 477 LKGNFKKE--GISLTIMAFIIKAVAHLLKEEREFAGHLSDDGKSVLLRKEIHMGIAVATP 534
K + +T + FI+KAVA L++ F LS+DG+ + L+K I++G+AV TP
Sbjct 444 QNEEAAKRKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTP 503
Query 535 DGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQGANFTISSLGAIGGTAFTP 594
+GL VPV ++ ++K I +++ EL I +KARD KL+ ++QG FTISS+G +G T F P
Sbjct 504 NGLVVPVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAP 563
Query 595 LVNWPQVAILGISPATMQPVWNGKDFDPRLMLPLSLSYDHRVINGADAARFTNKLTKLLQ 654
+VN P+VAILG+S + M+PVWNGK+F PRLMLP+SLS+DHRVI+GAD ARF + L
Sbjct 564 IVNAPEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLS 623
Query 655 DIRSLLI 661
DIR L++
Sbjct 624 DIRRLVM 630
Score = 95.9 bits (237), Expect = 9e-24
Identities = 52/120 (43%), Positives = 75/120 (63%), Gaps = 4/120 (3%)
Query 233 AVDVLVPDLGVDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKA 292
A+++ VPD+G D+ + EILV VGDK+ ++S++ VE DKA++EVPS +GIVK I V
Sbjct 2 AIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVSV 61
Query 293 GQDVKEGILLVTVE-AEGAVASAPKAPVAKAEAAPAPAAQKAEAPAAKVETAPQAGADKL 351
G + G L++ + A+GA +AP K EAAPA A A AAK P G+D++
Sbjct 62 GDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAA---PAAAAAKDVNVPDIGSDEV 118
>Q59638 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Pseudomonas aeruginosa
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG
12228 / 1C / PRS 101 / PAO1)]
Length=547
Score = 484 bits (1245), Expect = 3e-168
Identities = 273/553 (49%), Positives = 373/553 (67%), Gaps = 22/553 (4%)
Query 121 VQVPDIGVEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAGDT 180
++VPDIG + V ELLV GD++ + SL+ LESDKAS+E+PS +G ++SI+ K GDT
Sbjct 5 IRVPDIGNGEGEVIELLVKPGDKVEADQSLLTLESDKASMEIPSPKAGVVKSIKAKVGDT 64
Query 181 IQEGVLLLKVKTAGASNAAPAKQEAVVPTAAPVATKAETQAETPAVQ--SAPAGAV--DV 236
++EG +L+++ G A AK EA A P A KAE A P+ +APA A D+
Sbjct 65 LKEGDEILELEVEGGEQPAEAKAEAA--PAQPEAPKAEAPAPAPSESKPAAPAAASVQDI 122
Query 237 LVPDLG-VDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQD 295
VPD+G KA V E++V GD + D+S++ +ESDKA++E+PS SG+V+++ +K G +
Sbjct 123 KVPDIGSAGKANVIEVMVKAGDTVEADQSLITLESDKASMEIPSPASGVVESVSIKVGDE 182
Query 296 VKEGILLVTVEAEGAVASAPKAPVAKAEAAPAPAAQK---AEAPA-AKVETAPQAGADKL 351
V G L++ ++ EGA +A + P A A APAA++ A APA AK +T GA
Sbjct 183 VGTGDLILKLKVEGAAPAAEEQPAAAPAQAAAPAAEQKPAAAAPAPAKADTPAPVGAPS- 241
Query 352 TKEQEAENSKVYAGPAVRKLARELGVVLAQVKASGEHGRLMKEDIYAYVKQRLTAPVAAP 411
+ +KV+AGPAVR LARE GV L++VKASG GR++KED+ +VK++L A
Sbjct 242 -----RDGAKVHAGPAVRMLAREFGVELSEVKASGPKGRILKEDVQVFVKEQLQR--AKS 294
Query 412 KAAAAAVASGLPTLP--DFSAFGGVEEKTLTRLQQVSIPQLSLNNF-IPQVTQFDLADIT 468
A A +G+P +P DFS FG VEE +TRL QV L + +P VTQFD +DIT
Sbjct 295 GGAGATGGAGIPPIPEVDFSKFGEVEEVAMTRLMQVGAANLHRSWLNVPHVTQFDQSDIT 354
Query 469 ELEAWRNDLKGNFKKEGISLTIMAFIIKAVAHLLKEEREFAGHLSDDGKSVLLRKEIHMG 528
++EA+R K +K G+ LT++ ++KA AHLLKE +F L+ GK+++ +K +H+G
Sbjct 355 DMEAFRVAQKAAAEKAGVKLTVLPILLKACAHLLKELPDFNSSLAPSGKALIRKKYVHIG 414
Query 529 IAVATPDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQGANFTISSLGAIG 588
AV TPDGL VPV+R+ D+K++ Q+A E + KAR+KKLS +QGA FTISSLG IG
Sbjct 415 FAVDTPDGLLVPVIRDVDRKSLLQLAAEAADLADKARNKKLSADAMQGACFTISSLGHIG 474
Query 589 GTAFTPLVNWPQVAILGISPATMQPVWNGKDFDPRLMLPLSLSYDHRVINGADAARFTNK 648
GT FTP+VN P+VAILG+S ATMQPVW+GK F PRLMLPLSLSYDHRVINGA AARFT +
Sbjct 475 GTGFTPIVNAPEVAILGVSKATMQPVWDGKAFQPRLMLPLSLSYDHRVINGAAAARFTKR 534
Query 649 LTKLLQDIRSLLI 661
L +LL DIR+LL+
Sbjct 535 LGELLADIRTLLL 547
Score = 184 bits (467), Expect = 7e-54
Identities = 117/268 (44%), Positives = 164/268 (61%), Gaps = 27/268 (10%)
Query 3 VKTPDIGVDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLGDE 62
++ PDIG + V E+LVK GD + + SL+ LESDKAS+E+PS +GVVKSI +GD
Sbjct 5 IRVPDIGNGEGEVIELLVKPGDKVEADQSLLTLESDKASMEIPSPKAGVVKSIKAKVGDT 64
Query 63 VSEGTTLIEL--ESGDNTDKTESESAPAQTEV-KAETPVEQVAPQETKPATSTSAASSVV 119
+ EG ++EL E G+ + ++E+APAQ E KAE P AP E+KPA AA+SV
Sbjct 65 LKEGDEILELEVEGGEQPAEAKAEAAPAQPEAPKAEAPAP--APSESKPA--APAAASVQ 120
Query 120 EVQVPDIG-VEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAG 178
+++VPDIG KA V E++V GD + + SL+ LESDKAS+E+PS SG +ES+ +K G
Sbjct 121 DIKVPDIGSAGKANVIEVMVKAGDTVEADQSLITLESDKASMEIPSPASGVVESVSIKVG 180
Query 179 DTIQEGVLLLKVKTAGASNAAPAKQEAVVP--TAAPVATK-------AETQAETPAVQSA 229
D + G L+LK+K GA+ AA +Q A P AAP A + A +A+TPA A
Sbjct 181 DEVGTGDLILKLKVEGAAPAA-EEQPAAAPAQAAAPAAEQKPAAAAPAPAKADTPAPVGA 239
Query 230 PA---------GAVDVLVPDLGVDKAAV 248
P+ AV +L + GV+ + V
Sbjct 240 PSRDGAKVHAGPAVRMLAREFGVELSEV 267
>P45118 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Haemophilus influenzae
(strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=567
Score = 422 bits (1085), Expect = 6e-144
Identities = 253/576 (44%), Positives = 360/576 (63%), Gaps = 46/576 (8%)
Query 120 EVQVPDIGVEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAGD 179
++Q+PDIG ++ TV E++V+VGD I+ + S++ +E DKAS+EVP+ +G ++ I VK GD
Sbjct 4 QIQIPDIGSDEVTVTEVMVNVGDTISVDQSIINVEGDKASMEVPAPEAGVVKEILVKVGD 63
Query 180 TIQEGVLLLKVKTAGASNAAPAKQEAVVPTA-APVATKAETQAETPAVQSAPAGA--VDV 236
+ G +L ++ AGA APA E P A AP A P V +AP + V+V
Sbjct 64 KVSTGTPMLVLEAAGA---APAADEPTAPVADAPTA---------PVVATAPTASAIVEV 111
Query 237 LVPDLGVDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQDV 296
VPD+G D+ V EI+V VGD IT+++S++ VE DKA++EVP+ G+VK I VK+G V
Sbjct 112 NVPDIGGDEVNVTEIMVAVGDTITEEQSLITVEGDKASMEVPAPFGGVVKEILVKSGDKV 171
Query 297 KEGILLVTVEAEGAV----ASAPKAPVAKAEAAPAPAAQKAEAPAAKVET-APQAGADKL 351
G L++ E GA ASAP + A AAPA AQ +A A APQA A
Sbjct 172 STGSLIMRFEVLGAAPAESASAPASTSAPQTAAPATTAQAPQAAAPDTTAQAPQAAAPDT 231
Query 352 TKEQEAENSKV---------------YAGPAVRKLARELGVVLAQVKASGEHGRLMKEDI 396
T + N+ V +A P +R+LARE GV L +VK +G GR++KEDI
Sbjct 232 TAQAAQSNNNVSGLSQEQVEASTGYAHATPVIRRLAREFGVNLDKVKGTGRKGRIVKEDI 291
Query 397 YAYVKQRLTAPVAAPKAAAA----AVASGLPTLP----DFSAFGGVEEKTLTRLQQVSIP 448
AYVK + A + A A A +GL LP DFS FG +EE L+R+ ++S
Sbjct 292 EAYVKTAVKAYESGATAQATGNGVANGAGLGLLPWPKVDFSKFGEIEEVELSRINKISGA 351
Query 449 QLSLN-NFIPQVTQFDLADITELEAWRNDLKGNFKKE--GISLTIMAFIIKAVAHLLKEE 505
L N IP VT FD ADIT+LEA+R + +K+ G+ +T + FI+KAVA L+
Sbjct 352 NLHRNWVIIPHVTHFDKADITDLEAFRKEQNALREKQKLGVKITPVVFIMKAVAKALEAY 411
Query 506 REFAGHLSDDGKSVLLRKEIHMGIAVATPDGLTVPVLRNPDQKTIKQIAVELGVIGQKAR 565
F +++D + ++L+K I++G+AV TP+GL VPV +N ++K I +++ EL + +KAR
Sbjct 412 PRFNSSITEDAQRLILKKYINIGVAVDTPNGLVVPVFKNVNKKGIIELSRELMEVSKKAR 471
Query 566 DKKLSPKDLQGANFTISSLGAIGGTAFTPLVNWPQVAILGISPATMQPVWNGKDFDPRLM 625
+ KL+ D+QG FTISSLG IG T F P+VN P+VAILG+S ++M+PVWNGK+F PRL+
Sbjct 472 EGKLTASDMQGGCFTISSLGGIGTTHFAPIVNAPEVAILGVSKSSMEPVWNGKEFAPRLI 531
Query 626 LPLSLSYDHRVINGADAARFTNKLTKLLQDIRSLLI 661
LP+SLS+DHRVI+GAD ARF + L +L D+R L++
Sbjct 532 LPMSLSFDHRVIDGADGARFISYLGSVLADLRRLVM 567
Score = 175 bits (443), Expect = 2e-50
Identities = 106/241 (44%), Positives = 147/241 (61%), Gaps = 21/241 (9%)
Query 2 QVKTPDIGVDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLGD 61
Q++ PDIG D+ TV E++V VGDTIS + S+I +E DKAS+EVP+ +GVVK ILV +GD
Sbjct 4 QIQIPDIGSDEVTVTEVMVNVGDTISVDQSIINVEGDKASMEVPAPEAGVVKEILVKVGD 63
Query 62 EVSEGTTLIELESGDNTDKTESESAPAQTEVKAETPVEQVAPQETKPATSTS-AASSVVE 120
+VS GT ++ LE+ +APA A+ P VA T P +T+ AS++VE
Sbjct 64 KVSTGTPMLVLEAAG--------AAPA-----ADEPTAPVADAPTAPVVATAPTASAIVE 110
Query 121 VQVPDIGVEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAGDT 180
V VPDIG ++ V E++V+VGD I E SL+ +E DKAS+EVP+ G ++ I VK+GD
Sbjct 111 VNVPDIGGDEVNVTEIMVAVGDTITEEQSLITVEGDKASMEVPAPFGGVVKEILVKSGDK 170
Query 181 IQEGVLLLKVKTAGA----SNAAPAKQEAVVPTAAPVATKAETQAETP--AVQSAPAGAV 234
+ G L+++ + GA S +APA A TAAP T QA P Q+ A A
Sbjct 171 VSTGSLIMRFEVLGAAPAESASAPASTSA-PQTAAPATTAQAPQAAAPDTTAQAPQAAAP 229
Query 235 D 235
D
Sbjct 230 D 230
Score = 90.1 bits (222), Expect = 5e-22
Identities = 54/114 (47%), Positives = 67/114 (59%), Gaps = 11/114 (10%)
Query 1 MQVKTPDIGVDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLG 60
++V PDIG D+ V EI+V VGDTI+E SLI +E DKAS+EVP+ GVVK ILV G
Sbjct 109 VEVNVPDIGGDEVNVTEIMVAVGDTITEEQSLITVEGDKASMEVPAPFGGVVKEILVKSG 168
Query 61 DEVSEGTTLIELESGDNTDKTESESAPAQTEVKAETPVEQVAPQETKPATSTSA 114
D+VS G+ ++ E ES SAPA T APQ PAT+ A
Sbjct 169 DKVSTGSLIMRFEV-LGAAPAESASAPASTS----------APQTAAPATTAQA 211
>Q59098 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Cupriavidus necator (strain
ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 /
Stanier 337)]
Length=553
Score = 416 bits (1069), Expect = 9e-142
Identities = 252/569 (44%), Positives = 347/569 (61%), Gaps = 40/569 (7%)
Query 116 SSVVEVQVPDIG-VEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIE 174
S +E++VPDIG + V E+ V GD I D+LV LESDKA+++VPS +G ++ +
Sbjct 2 SQAIEIKVPDIGDYDAVPVIEVHVKPGDSINAEDALVTLESDKATMDVPSPQAGVVKDVR 61
Query 175 VKAGDTIQEGVLLLKVKTAGASNAAPAKQEAVVPTAAPVATKAETQAETPAVQSAPA--- 231
+K GD + EG +L+ ++ A AAPA P AA A A A PA +APA
Sbjct 62 IKVGDNVSEGSVLVMLEAANEPAAAPA------PAAAAPAPAAAAPAPAPAPAAAPAAAP 115
Query 232 -----GAVDVLVPDLG-VDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIV 285
G ++V VPD+G D V E+ V GD I ++++V +ESDKAT++VPS G+V
Sbjct 116 AAGGGGTIEVKVPDIGDYDAVPVIEVHVKAGDTINAEDAVVTLESDKATMDVPSPQGGVV 175
Query 286 KAIHVKAGQDVKEGILLVTVE-----AEGAVASAPKAPVAKAEA-APAPAAQKAEAPAAK 339
K + VK G +V EG LL+ +E A A A+A AP A A A APAPAA A APAA
Sbjct 176 KEVKVKVGDNVAEGTLLLILEGAAASAAPAAAAAAPAPAASAPAPAPAPAAA-APAPAAA 234
Query 340 VETAPQAGADKLTKEQEAENSKVYAGPAVRKLARELGVVLAQVKASGEHGRLMKEDIYAY 399
AP A +A P+VRK ARELGV +++V +G GR+ +ED+ Y
Sbjct 235 PAAAPAAAG--------VTGKAAHASPSVRKFARELGVDVSRVPGTGPKGRITQEDVQGY 286
Query 400 VKQRLTAPVAAPKAAAAAVASG--LPTLP----DFSAFGGVEEKTLTRLQQVSIPQLSLN 453
VK ++ AAP AAAA A G L LP DF+ FG VE K L+R++++S L N
Sbjct 287 VKGVMSGQAAAPAQAAAAGAGGGELGLLPWPKFDFTRFGEVESKALSRIKKISGANLHRN 346
Query 454 -NFIPQVTQFDLADITELEAWRNDLKGNFKKEGISLTIMAFIIKAVAHLLKEEREFAGHL 512
IP VT D ADITELEA+R L +K GI +T++AF+IKA LK+ F L
Sbjct 347 WVMIPHVTNHDEADITELEAFRLQLNKENEKSGIKVTMLAFMIKATVAALKKFPNFNASL 406
Query 513 SDDGKSVLLRKEIHMGIAVATPDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPK 572
DG +++L+K ++G A TP+GL VPV+++ D+K + +I+ E+ + + ARD KL P
Sbjct 407 --DGDNLVLKKYFNIGFAADTPNGLVVPVIKDADKKGVLEISQEMSELAKLARDGKLKPD 464
Query 573 DLQGANFTISSLGAIGGTAFTPLVNWPQVAILGISPATMQPVWNGKDFDPRLMLPLSLSY 632
+QG F+ISSLG +GGT FTP++N P+VAI+G+ + +PVW+GK F PRL LPLSLS+
Sbjct 465 QMQGGCFSISSLGGLGGTYFTPIINAPEVAIMGVCKSYQKPVWDGKQFAPRLTLPLSLSW 524
Query 633 DHRVINGADAARFTNKLTKLLQDIRSLLI 661
DHRVI+GA+AARF +LL D R +L+
Sbjct 525 DHRVIDGAEAARFNTYFGQLLADFRRILL 553
Score = 161 bits (408), Expect = 9e-46
Identities = 94/235 (40%), Positives = 134/235 (57%), Gaps = 3/235 (1%)
Query 1 MQVKTPDIG-VDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSL 59
+++K PDIG D V E+ VK GD+I+ D+L+ LESDKA+++VPS +GVVK + + +
Sbjct 5 IEIKVPDIGDYDAVPVIEVHVKPGDSINAEDALVTLESDKATMDVPSPQAGVVKDVRIKV 64
Query 60 GDEVSEGTTLIELESGDNTDKTESESAPAQTEVKAETPVEQVAPQETKPATSTSAASSVV 119
GD VSEG+ L+ LE+ + + +A A A P AP A + +
Sbjct 65 GDNVSEGSVLVMLEAANEPAAAPAPAAAAPAPA-AAAPAPAPAPAAAPAAAPAAGGGGTI 123
Query 120 EVQVPDIG-VEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAG 178
EV+VPDIG + V E+ V GD I D++V LESDKA+++VPS G ++ ++VK G
Sbjct 124 EVKVPDIGDYDAVPVIEVHVKAGDTINAEDAVVTLESDKATMDVPSPQGGVVKEVKVKVG 183
Query 179 DTIQEGVLLLKVKTAGASNAAPAKQEAVVPTAAPVATKAETQAETPAVQSAPAGA 233
D + EG LLL ++ A AS A A A P A+ A A PA +APA A
Sbjct 184 DNVAEGTLLLILEGAAASAAPAAAAAAPAPAASAPAPAPAPAAAAPAPAAAPAAA 238
Score = 84.3 bits (207), Expect = 3e-20
Identities = 48/122 (39%), Positives = 68/122 (56%), Gaps = 1/122 (1%)
Query 1 MQVKTPDIG-VDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSL 59
++VK PDIG D V E+ VK GDTI+ D+++ LESDKA+++VPS GVVK + V +
Sbjct 123 IEVKVPDIGDYDAVPVIEVHVKAGDTINAEDAVVTLESDKATMDVPSPQGGVVKEVKVKV 182
Query 60 GDEVSEGTTLIELESGDNTDKTESESAPAQTEVKAETPVEQVAPQETKPATSTSAASSVV 119
GD V+EGT L+ LE + + +A A P A PA + +AA +
Sbjct 183 GDNVAEGTLLLILEGAAASAAPAAAAAAPAPAASAPAPAPAPAAAAPAPAAAPAAAPAAA 242
Query 120 EV 121
V
Sbjct 243 GV 244
>P35489 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Acholeplasma laidlawii]
Length=544
Score = 285 bits (729), Expect = 2e-91
Identities = 186/544 (34%), Positives = 285/544 (52%), Gaps = 21/544 (4%)
Query 127 GVEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAGDTIQEGVL 186
G+ + TV + VGD++ E ++LV++E+DK + E+PS V GTI S+ K G+ I G +
Sbjct 12 GIHEGTVLQWNFKVGDKVKEGETLVIVETDKVNAELPSPVDGTIVSLGAKEGEEIHVGQI 71
Query 187 LLKVKTA-GASNAAPAKQEAVVPTAAPVATKAETQAETPAVQSAPAGAVDVLVPDLG--V 243
++ + G AAPA + PT AP A A A +A D D+G +
Sbjct 72 IVTIDDGTGTPAAAPAPAQVSAPTPAPAA------APQVAAPAASGDIYDFKFADIGEGI 125
Query 244 DKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQDVKEGILLV 303
+ + + VGDK+ + E++VVVE+DK E+PS V G + + G+ + G +V
Sbjct 126 HEGTILQWNFKVGDKVKEGETLVVVETDKVNAELPSPVDGTILKLGKAEGEVIHVGETVV 185
Query 304 TVEAEGAVASAPKAPVAKAEAAPAPAAQKAEAPAAKVETAPQAGADKLTKEQEAENSKVY 363
+ GA +AP A+A P +K ++E + A KV
Sbjct 186 LIGQNGATLEQAQAPKAEA---PVSEPKKGAGVVGEIEVSDDIIGGSEEVHVVATTGKVL 242
Query 364 AGPAVRKLARELGVVLAQVKASGEHGRLMKEDIY-AYVKQRLTAPVAAPKAAAAAVASGL 422
A P RKLA +LGV +A +K SGE GR+MK+D+ + APV +A A A AS
Sbjct 243 ASPVARKLASDLGVDIATIKGSGEQGRVMKDDVQNSKAPAEAQAPVQQTQAPAQAAAS-- 300
Query 423 PTLPDFSAFG----GVEEKTLTRLQQ-VSIPQLSLNNFIPQVTQFDLADITELEAWRNDL 477
P F+A G VE +TRL++ VS + IP+ D ++ L +RN+
Sbjct 301 -VAPSFAAAGKPQGDVEVVKITRLRKAVSNAMTRSKSIIPETVLMDEINVDALVNFRNEA 359
Query 478 KGNFKKEGISLTIMAFIIKAVAHLLKEEREFAGHLSDDGKSVLLRKEIHMGIAVATPDGL 537
KG + +GI LT MAFI KAV LKE F + D V ++K I++G+AV TPDGL
Sbjct 360 KGLAESKGIKLTYMAFIAKAVLIALKEFPMFNASFNHDTDEVYIKKFINLGMAVDTPDGL 419
Query 538 TVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQGANFTISSLGAIGGTAFTPLVN 597
VP ++N D+ ++ ++A ++ + +K+S G FTI++ G+ G TP++N
Sbjct 420 IVPNIKNADRLSVFELASQVRSLADDTIARKISMDQQTGGTFTITNFGSAGIAFGTPVIN 479
Query 598 WPQVAILGISPATMQPVWNGKDFDPRLMLPLSLSYDHRVINGADAARFTNKLTKLLQDIR 657
+P++AILGI +P G + LPLSL+ DHR+I+GAD RF ++ +LL +
Sbjct 480 YPELAILGIGKIDRKPWVVGNEIKIAHTLPLSLAVDHRIIDGADGGRFLMRVKELLTNPT 539
Query 658 SLLI 661
LL+
Sbjct 540 LLLL 543
Score = 116 bits (291), Expect = 1e-30
Identities = 92/341 (27%), Positives = 158/341 (46%), Gaps = 44/341 (13%)
Query 9 GVDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLGDEVSEGTT 68
G+ + TV + KVGD + E ++L+++E+DK + E+PS G + S+ G+E+ G
Sbjct 12 GIHEGTVLQWNFKVGDKVKEGETLVIVETDKVNAELPSPVDGTIVSLGAKEGEEIHVGQI 71
Query 69 LIELESGDNTDKTESESAPAQTEVKAETPVEQVAPQETKPATSTSAASSVVEVQVPDI-- 126
++ ++ G T +APA +V A TP APQ PA A+ + + + DI
Sbjct 72 IVTIDDGTGT----PAAAPAPAQVSAPTPAPAAAPQVAAPA----ASGDIYDFKFADIGE 123
Query 127 GVEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAGDTIQEGVL 186
G+ + T+ + VGD++ E ++LV++E+DK + E+PS V GTI + G+ I G
Sbjct 124 GIHEGTILQWNFKVGDKVKEGETLVVVETDKVNAELPSPVDGTILKLGKAEGEVIHVGET 183
Query 187 LLKVKTAGASNAAPAKQEAVVPTAAPVATKAETQAETPAVQSAPAGAVDVLVPDLGVDK- 245
++ + GA+ ++A P KAE P + G ++V +G +
Sbjct 184 VVLIGQNGAT-----LEQAQAP-------KAEAPVSEPKKGAGVVGEIEVSDDIIGGSEE 231
Query 246 ----AAVAEILVN-VGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQDVKEGI 300
A ++L + V K+ D + D AT++ ++K DV+
Sbjct 232 VHVVATTGKVLASPVARKLASDLGV-----DIATIKGSGEQGRVMK-------DDVQNSK 279
Query 301 LLVTVEAEGAVASAPKAPVAKAEAAPAPAAQKAEAPAAKVE 341
+A AP A+A A+ AP+ A P VE
Sbjct 280 APAEAQAPVQQTQAP----AQAAASVAPSFAAAGKPQGDVE 316
>Q8NNJ2 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Corynebacterium glutamicum
(strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 /
LMG 3730 / NCIMB 10025)]
Length=675
Score = 286 bits (731), Expect = 3e-90
Identities = 207/675 (31%), Positives = 329/675 (49%), Gaps = 37/675 (5%)
Query 3 VKTPDIG--VDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLG 60
V+ P++G V + T+ + L VGDT+ ++ L+ + +DK E+PS +GV+ I
Sbjct 5 VEMPELGESVTEGTITQWLKSVGDTVEVDEPLLEVSTDKVDTEIPSPVAGVILEIKAEED 64
Query 61 DEVSEGTTLIELESGDNTDKTESESAPAQTEVKAETPVEQVAPQETKPATSTSAASSVVE 120
D V G + + D T E+ + A + E PV++ +E P + +A + +
Sbjct 65 DTVDVGGVIAIIGDADETPANEAPADEAPAPAEEEEPVKEEPKKEAAPE-APAATGAATD 123
Query 121 VQVPDIG--VEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAG 178
V++P++G V + T+ + L +VGD + ++ L+ + +DK E+PS V+GTI I
Sbjct 124 VEMPELGESVTEGTITQWLKAVGDTVEVDEPLLEVSTDKVDTEIPSPVAGTIVEILADED 183
Query 179 DTIQEGVLLLKVKTAGASNAAPAKQEAVVPTAAPVATKAETQAET-PAVQSAPAGAVDVL 237
DT+ G ++ ++ A A+ AAPA++EA P K E + E P +A A DV
Sbjct 184 DTVDVGAVIARIGDANAA-AAPAEEEAA-PAEEEEPVKEEPKKEAAPEAPAATGAATDVE 241
Query 238 VPDLG--VDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQD 295
+P+LG V + + + L VGD + DE ++ V +DK E+PS V+G + I
Sbjct 242 MPELGESVTEGTITQWLKAVGDTVEVDEPLLEVSTDKVDTEIPSPVAGTIVEILADEDDT 301
Query 296 VKEGILLVTV-EAEGAVASAPKAPVAKAEAAPAPAAQKAEAPAA---KVETAPQAGADKL 351
V G ++ + +A A A A + E P K E P K E A A
Sbjct 302 VDVGAVIARIGDANAAAAPAEEEAAPAEEEEPVKEEPKKEEPKKEEPKKEAATTPAAASA 361
Query 352 TKEQEAENSKVYAGPAVRKLARELGVVLAQVKASGEHGRLMKEDIYAYVKQRLTAPVAAP 411
T +N Y P VRKLA + GV L V +G GR+ K+D+ A AAP
Sbjct 362 TVSASGDNVP-YVTPLVRKLAEKHGVDLNTVTGTGIGGRIRKQDVLAAANGE-----AAP 415
Query 412 KAAAAAVA--SGLPTLPDFSAFGGVEEKT-----LTRLQQVSIPQLSLNNFIPQVTQFDL 464
AAA V+ S P+ + G +K +T ++ V Q+S Q+TQ
Sbjct 416 AEAAAPVSAWSTKSVDPEKAKLRGTTQKVNRIREITAMKTVEALQISA-----QLTQLHE 470
Query 465 ADITELEAWRNDLKGNF-KKEGISLTIMAFIIKAVAHLLKEEREFAGHLSDDGKSVLLRK 523
D+T + R K F +K G++LT + F +KAV L + K +
Sbjct 471 VDMTRVAELRKKNKPAFIEKHGVNLTYLPFFVKAVVEALVSHPNVNASFNAKTKEMTYHS 530
Query 524 EIHMGIAVATPDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQGANFTISS 583
+++ IAV TP GL PV+ + +I +IA + + ++R+ KL P DL G FTI++
Sbjct 531 SVNLSIAVDTPAGLLTPVIHDAQDLSIPEIAKAIVDLADRSRNNKLKPNDLSGGTFTITN 590
Query 584 LGAIGGTAFTPLVNWPQVAILGISPATMQPVWNGKD----FDPRLMLPLSLSYDHRVING 639
+G+ G + TP++ PQ ILG +PV +D R M+ L L+YDH+V++G
Sbjct 591 IGSEGALSDTPILVPPQAGILGTGAIVKRPVVITEDGIDSIAIRQMVFLPLTYDHQVVDG 650
Query 640 ADAARFTNKLTKLLQ 654
ADA RF + L+
Sbjct 651 ADAGRFLTTIKDRLE 665
>Q8K9T8 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Buchnera aphidicola subsp.
Schizaphis graminum (strain Sg)]
Length=402
Score = 267 bits (682), Expect = 3e-86
Identities = 164/429 (38%), Positives = 250/429 (58%), Gaps = 32/429 (7%)
Query 238 VPDLGVDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQDVK 297
+PD+G+++ V EILV +G++I D+ ++ VE DKA++E+PS +SGIVK I +K G+ VK
Sbjct 1 MPDIGLEEVEVTEILVKIGEEIKLDQGLITVEGDKASMEIPSPISGIVKDITIKIGEKVK 60
Query 298 EGILLVTVEAEGAVASAPKAPVAKAEAAPAPAAQKAEAPAAKVETAPQAGADKLTKEQEA 357
+++ + + K E ++T + + L ++++
Sbjct 61 TSSIIMIFKVNNLNSI------------------KNEKDLNYIKTEKKLNENFLEEKKDI 102
Query 358 ENSK-VYAGPAVRKLARELGVVLAQVKASGEHGRLMKEDIYAYVKQRLTAPVAAPKAAAA 416
+ V+A P VR+LAR L V L + SG R++KEDI Y++ + ++
Sbjct 103 KKIVLVHATPVVRRLARHLNVDLKNITPSGPKNRILKEDIELYIRNNTS------NKSSF 156
Query 417 AVASGLPTLPDFSAFGGVEEKTLTRLQQVSIPQLSLNNF-IPQVTQFDLADITELEAWRN 475
+ T F E +T +QQ+ L N IP VTQFD +IT LE +R+
Sbjct 157 NIEKNNTTNFHKDLFN---EIPITNIQQIIGKNLHQNWVNIPHVTQFDEVNITLLEEFRH 213
Query 476 DLKGNFKKEG---ISLTIMAFIIKAVAHLLKEEREFAGHLSDDGKSVLLRKEIHMGIAVA 532
K++ +TI+ FIIK+VA+ L E F LS + K++ L+K +++GIAV
Sbjct 214 KYNTEKKQKNNMCSKITILPFIIKSVAYGLLEFPIFNSSLSVNKKTIFLKKYVNVGIAVD 273
Query 533 TPDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQGANFTISSLGAIGGTAF 592
+ L VPVL+N D+K I ++ EL + +KA + KL D++ FTIS+LG IGG+ F
Sbjct 274 VQNALFVPVLKNVDKKNIANLSSELIFLSKKAHENKLDASDMKDGCFTISNLGGIGGSWF 333
Query 593 TPLVNWPQVAILGISPATMQPVWNGKDFDPRLMLPLSLSYDHRVINGADAARFTNKLTKL 652
+P++N P+VAILG+S A ++P+WNGK+F P LMLPLSLSYDHRVINGADAARF + K+
Sbjct 334 SPIINSPEVAILGVSKALIKPLWNGKEFIPSLMLPLSLSYDHRVINGADAARFLTFIGKM 393
Query 653 LQDIRSLLI 661
L DIR L++
Sbjct 394 LSDIRFLIM 402
Score = 68.6 bits (166), Expect = 2e-15
Identities = 35/89 (39%), Positives = 57/89 (64%), Gaps = 1/89 (1%)
Query 6 PDIGVDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLGDEVSE 65
PDIG+++ V EILVK+G+ I + LI +E DKAS+E+PS SG+VK I + +G++V
Sbjct 2 PDIGLEEVEVTEILVKIGEEIKLDQGLITVEGDKASMEIPSPISGIVKDITIKIGEKVKT 61
Query 66 GTTLIELESGD-NTDKTESESAPAQTEVK 93
+ ++ + + N+ K E + +TE K
Sbjct 62 SSIIMIFKVNNLNSIKNEKDLNYIKTEKK 90
Score = 65.1 bits (157), Expect = 3e-14
Identities = 27/69 (39%), Positives = 48/69 (70%), Gaps = 0/69 (0%)
Query 123 VPDIGVEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAGDTIQ 182
+PDIG+E+ V E+LV +G+EI + L+ +E DKAS+E+PS +SG ++ I +K G+ ++
Sbjct 1 MPDIGLEEVEVTEILVKIGEEIKLDQGLITVEGDKASMEIPSPISGIVKDITIKIGEKVK 60
Query 183 EGVLLLKVK 191
+++ K
Sbjct 61 TSSIIMIFK 69
>P57302 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Buchnera aphidicola subsp.
Acyrthosiphon pisum (strain APS)]
Length=396
Score = 259 bits (661), Expect = 3e-83
Identities = 157/433 (36%), Positives = 244/433 (56%), Gaps = 46/433 (11%)
Query 238 VPDLGVDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQDVK 297
+PD+G+++ + EILV++ +KI ++ ++ VE DK ++E+PS +SGIVK I +K G+ +K
Sbjct 1 MPDIGLEEVEIIEILVSINEKIAPEQGLITVEGDKTSMEIPSPISGIVKHIFIKIGEKIK 60
Query 298 EGILLVTVEAEGAVASAPKAPVAKAEAAPAPAAQKAEAPAAKVETAPQAGADKLTKEQEA 357
L++ E E K K E ++
Sbjct 61 TDALIMRCEVENIDFHVKK----------------------KEEICLDNNVLNKVEKNFK 98
Query 358 ENSKVYAGPAVRKLARELGVVLAQVKASGEHGRLMKEDIYAYVKQRLTAPVAAPKAAAAA 417
++ +A P +R+LAR L + L V +G R++KED+ Y
Sbjct 99 KDIFFHATPLIRRLARNLNINLYDVVGTGPKNRILKEDLDLYQSN--------------- 143
Query 418 VASGLPTLPDFSAFGGVEEKTLTRLQQVSIPQLSLNNF------IPQVTQFDLADITELE 471
+ L + FG ++ L+ I + NN IP VTQFD DIT LE
Sbjct 144 IKENLIEEKNKINFGDSKKSKTKELELSDIQKNIGNNLHRNWMNIPHVTQFDEVDITILE 203
Query 472 AWR---NDLKGNFKKEGISLTIMAFIIKAVAHLLKEEREFAGHLSDDGKSVLLRKEIHMG 528
+R N+ K N KK ++TI+ FIIK VA+ L++ F L+ + K ++L+K I++G
Sbjct 204 KFRQKYNNEKRNQKKTNENITILVFIIKVVAYALEKFPIFNSSLNINNKKIILKKYINIG 263
Query 529 IAVATPDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQGANFTISSLGAIG 588
A+ + L VPVL++ ++K IKQ++ EL ++ +KAR +KL+ +D+ G FTIS+LG IG
Sbjct 264 FAIDVNNDLFVPVLKDVNKKNIKQLSSELILLSEKARTRKLNIEDMTGGCFTISNLGGIG 323
Query 589 GTAFTPLVNWPQVAILGISPATMQPVWNGKDFDPRLMLPLSLSYDHRVINGADAARFTNK 648
G+ F+P++N P+VAILGIS + ++P WNGK+F P LMLPLSLSYDHRVINGA AARF
Sbjct 324 GSWFSPIINSPEVAILGISKSQIKPSWNGKEFIPSLMLPLSLSYDHRVINGAYAARFITF 383
Query 649 LTKLLQDIRSLLI 661
++++L D+ L++
Sbjct 384 ISRVLSDMHFLIM 396
Score = 64.7 bits (156), Expect = 3e-14
Identities = 28/82 (34%), Positives = 51/82 (62%), Gaps = 0/82 (0%)
Query 123 VPDIGVEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAGDTIQ 182
+PDIG+E+ + E+LVS+ ++IA L+ +E DK S+E+PS +SG ++ I +K G+ I+
Sbjct 1 MPDIGLEEVEIIEILVSINEKIAPEQGLITVEGDKTSMEIPSPISGIVKHIFIKIGEKIK 60
Query 183 EGVLLLKVKTAGASNAAPAKQE 204
L+++ + K+E
Sbjct 61 TDALIMRCEVENIDFHVKKKEE 82
Score = 60.5 bits (145), Expect = 8e-13
Identities = 25/68 (37%), Positives = 43/68 (63%), Gaps = 0/68 (0%)
Query 6 PDIGVDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLGDEVSE 65
PDIG+++ + EILV + + I+ LI +E DK S+E+PS SG+VK I + +G+++
Sbjct 2 PDIGLEEVEIIEILVSINEKIAPEQGLITVEGDKTSMEIPSPISGIVKHIFIKIGEKIKT 61
Query 66 GTTLIELE 73
++ E
Sbjct 62 DALIMRCE 69
>Q89AQ9 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Buchnera aphidicola subsp.
Baizongia pistaciae (strain Bp)]
Length=410
Score = 253 bits (647), Expect = 5e-81
Identities = 157/429 (37%), Positives = 241/429 (56%), Gaps = 24/429 (6%)
Query 238 VPDLGVDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQDVK 297
+PD+G D V EILV +GD++ KD+S++ VE KA++E+P++ +G +K I V G+ +
Sbjct 1 MPDIGTDLVEVIEILVKIGDQVKKDDSLITVEGQKASIEIPASHTGTIKNIIVHIGEKIT 60
Query 298 EGILLVTVEAEGAVASAPKAPVAKAEAAPAPAAQKAEAPAAKVETAPQAGADKLTKEQEA 357
G L+ A+ + V + + + + ++ T+ + +
Sbjct 61 TGSLI-------AILNGIDDNVKSKNDSSSYSFKNSK------NTSTNSNLGNVNNNINN 107
Query 358 ENSKVYAGPAVRKLARELGVVLAQVKASGEHGRLMKEDIYAYVKQRLTAPVAAP-KAAAA 416
V+A P VR+LAR+ + L + +G GR++KED+ +Y L + K
Sbjct 108 RTILVHATPTVRRLARKFDIKLENITGTGRKGRILKEDVISYKNISLFNDIKKSLKKTNV 167
Query 417 AVASGLPTLPDFSAFGGVEEKTLTRLQQVSIPQLSLNNF-IPQVTQFDLADITELEAWRN 475
T DF + LTR Q S L + IP VTQFD +DITELE +R
Sbjct 168 NYYKDNVTCDDFKSI------ELTRTQIRSSKNLLKSWLTIPHVTQFDESDITELENFRQ 221
Query 476 DLKGNFKKEGISLTIMAFIIKAVAHLLKEEREFAGHL--SDDGKSVLLRKEIHMGIAVAT 533
+ K + LTI+ F+IKAV+ L+ +F G L D+ +++L + I++GI V T
Sbjct 222 KYNSDLKDKSKKLTILIFVIKAVSKALEMFPKFNGRLINKDNRIAIVLNEHINIGIVVDT 281
Query 534 PDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQG-ANFTISSLGAIGGTAF 592
DGL VPV+ ++K I I+ +L +I ++AR +KL+ D++ +FTIS+LG IGGT F
Sbjct 282 DDGLLVPVINRVNKKNISSISNDLRIISERARSRKLNFSDIKEYGSFTISNLGGIGGTNF 341
Query 593 TPLVNWPQVAILGISPATMQPVWNGKDFDPRLMLPLSLSYDHRVINGADAARFTNKLTKL 652
TP++ +P++AILGIS A ++P WN F P+LMLPLSLSYDHR I+G A RF + K+
Sbjct 342 TPIIKYPELAILGISRALIKPYWNSHAFIPKLMLPLSLSYDHRAIDGVAAVRFITFVKKM 401
Query 653 LQDIRSLLI 661
L DIR L+I
Sbjct 402 LTDIRFLMI 410
Score = 76.3 bits (186), Expect = 7e-18
Identities = 33/81 (41%), Positives = 59/81 (73%), Gaps = 0/81 (0%)
Query 6 PDIGVDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLGDEVSE 65
PDIG D V EILVK+GD + ++DSLI +E KAS+E+P++ +G +K+I+V +G++++
Sbjct 2 PDIGTDLVEVIEILVKIGDQVKKDDSLITVEGQKASIEIPASHTGTIKNIIVHIGEKITT 61
Query 66 GTTLIELESGDNTDKTESESA 86
G+ + L D+ K++++S+
Sbjct 62 GSLIAILNGIDDNVKSKNDSS 82
Score = 63.9 bits (154), Expect = 6e-14
Identities = 28/65 (43%), Positives = 47/65 (72%), Gaps = 0/65 (0%)
Query 123 VPDIGVEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAGDTIQ 182
+PDIG + V E+LV +GD++ ++DSL+ +E KAS+E+P++ +GTI++I V G+ I
Sbjct 1 MPDIGTDLVEVIEILVKIGDQVKKDDSLITVEGQKASIEIPASHTGTIKNIIVHIGEKIT 60
Query 183 EGVLL 187
G L+
Sbjct 61 TGSLI 65
Score = 21.6 bits (44), Expect = 1.2
Identities = 14/48 (29%), Positives = 23/48 (48%), Gaps = 2/48 (4%)
Query 162 VPSTVSGTIESIE--VKAGDTIQEGVLLLKVKTAGASNAAPAKQEAVV 207
+P + +E IE VK GD +++ L+ V+ AS PA +
Sbjct 1 MPDIGTDLVEVIEILVKIGDQVKKDDSLITVEGQKASIEIPASHTGTI 48
>P9WIS7 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=553
Score = 232 bits (591), Expect = 3e-71
Identities = 180/554 (32%), Positives = 268/554 (48%), Gaps = 33/554 (6%)
Query 121 VQVPDIG--VEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAG 178
VQ+P +G V + TV L GD + ++ LV + +DK E+PS +G + I +
Sbjct 5 VQMPALGESVTEGTVTRWLKQEGDTVELDEPLVEVSTDKVDTEIPSPAAGVLTKIIAQED 64
Query 179 DTIQEGVLLLKVKTAGASNAAPAKQEAVVPTAAPVATKAETQAETPAVQSAPAG--AVDV 236
DT++ G L + A + A A VP A P + A APAG A V
Sbjct 65 DTVEVGGELAVIGDAKDAGEAAAPAPEKVPAAQPESKPAPEPPPVQPTSGAPAGGDAKPV 124
Query 237 LVPDLG--VDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQ 294
L+P+LG V + V L +GD + DE +V V +DK E+PS V+G++ +I
Sbjct 125 LMPELGESVTEGTVIRWLKKIGDSVQVDEPLVEVSTDKVDTEIPSPVAGVLVSISADEDA 184
Query 295 DVKEG--ILLVTVEAEGAVASAPK-APVAKAEAAPAPAAQKAEAPAAKVETAPQAGADKL 351
V G + + V A+ A APK AP E AP P A+ A +P A A AGA
Sbjct 185 TVPVGGELARIGVAADIGAAPAPKPAPKPVPEPAPTPKAEPAPSPPA----AQPAGA--- 237
Query 352 TKEQEAENSKVYAGPAVRKLARELGVVLAQVKASGEHGRLMKEDIYAYVKQRLTAPVAAP 411
AE + Y P VRKLA E + LA V +G GR+ K+D+ A +Q+ A AP
Sbjct 238 -----AEGAP-YVTPLVRKLASENNIDLAGVTGTGVGGRIRKQDVLAAAEQKKRAKAPAP 291
Query 412 KA-AAAAVASGLPTLPD--FSAFGGVEEKTLTRLQQVSIPQLSLN-NFIPQVTQFDLADI 467
A AAAA A P P + G +K +R++Q++ + + Q+TQ D+
Sbjct 292 AAQAAAAPAPKAPPAPAPALAHLRGTTQKA-SRIRQITANKTRESLQATAQLTQTHEVDM 350
Query 468 TELEAWRNDLKGNF-KKEGISLTIMAFIIKAVAHLLKEEREFAGHLSDDGKSVLLRKEIH 526
T++ R K F ++EG++LT + F KAV LK ++D K + H
Sbjct 351 TKIVGLRARAKAAFAEREGVNLTFLPFFAKAVIDALKIHPNINASYNEDTKEITYYDAEH 410
Query 527 MGIAVATPDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQGANFTISSLGA 586
+G AV T GL PV+ + ++ +A + I +AR L P +L G FTI+++G+
Sbjct 411 LGFAVDTEQGLLSPVIHDAGDLSLAGLARAIADIAARARSGNLKPDELSGGTFTITNIGS 470
Query 587 IGGTAFTPLVNWPQVAILGISPATMQP-----VWNGKDFDPRLMLPLSLSYDHRVINGAD 641
G TP++ PQ A+LG +P + R + L L+YDHR+I+GAD
Sbjct 471 QGALFDTPILVPPQAAMLGTGAIVKRPRVVVDASGNESIGVRSVCYLPLTYDHRLIDGAD 530
Query 642 AARFTNKLTKLLQD 655
A RF + L++
Sbjct 531 AGRFLTTIKHRLEE 544
Score = 124 bits (310), Expect = 6e-33
Identities = 110/362 (30%), Positives = 163/362 (45%), Gaps = 35/362 (10%)
Query 3 VKTPDIG--VDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLG 60
V+ P +G V + TV L + GDT+ ++ L+ + +DK E+PS A+GV+ I+
Sbjct 5 VQMPALGESVTEGTVTRWLKQEGDTVELDEPLVEVSTDKVDTEIPSPAAGVLTKIIAQED 64
Query 61 DEVSEGTTLIELESGDNTDKTESESAPAQTEVKAETPVEQVAPQ--ETKPATSTSAASSV 118
D V G L + GD D E+ +APA +V A P + AP+ +P + A
Sbjct 65 DTVEVGGELAVI--GDAKDAGEA-AAPAPEKVPAAQPESKPAPEPPPVQPTSGAPAGGDA 121
Query 119 VEVQVPDIG--VEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVK 176
V +P++G V + TV L +GD + ++ LV + +DK E+PS V+G + SI
Sbjct 122 KPVLMPELGESVTEGTVIRWLKKIGDSVQVDEPLVEVSTDKVDTEIPSPVAGVLVSISAD 181
Query 177 AGDTIQEGVLLLKVKTAGASNAAPAKQEAVVPTAAPVAT-KAETQAETPAVQSAPAGAVD 235
T+ G L ++ A AAPA + A P P T KAE PA Q PAGA
Sbjct 182 EDATVPVGGELARIGVAADIGAAPAPKPAPKPVPEPAPTPKAEPAPSPPAAQ--PAGA-- 237
Query 236 VLVPDLGVDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQD 295
A A + + K+ + +I D A V + V G ++ V A +
Sbjct 238 ----------AEGAPYVTPLVRKLASENNI-----DLAGV-TGTGVGGRIRKQDVLAAAE 281
Query 296 VKEGILLVTVEAEGAVASAPKAPVAKAEAAPAPAAQKAEAPAAKVETAPQAGADKLTKEQ 355
K+ A+ A A APKAP APAPA K Q A+K +
Sbjct 282 QKKRAKAPAPAAQAAAAPAPKAP-----PAPAPALAHLRGTTQKASRIRQITANKTRESL 336
Query 356 EA 357
+A
Sbjct 337 QA 338
>P11961 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Geobacillus stearothermophilus]
Length=428
Score = 227 bits (579), Expect = 7e-71
Identities = 145/432 (34%), Positives = 235/432 (54%), Gaps = 10/432 (2%)
Query 233 AVDVLVPDLG--VDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHV 290
A + +PD+G + + + + V GD++ +D+ + V++DKA VE+PS V G V I V
Sbjct 2 AFEFKLPDIGEGIHEGEIVKWFVKPGDEVNEDDVLCEVQNDKAVVEIPSPVKGKVLEILV 61
Query 291 KAGQDVKEGILLVTVEAEGAVASAPKAPVAKAEAAPAPAAQKAEAPAAKVETAPQAGADK 350
G G L+T++A G K E A +K E + + + A
Sbjct 62 PEGTVATVGQTLITLDAPGYENMTFKGQ----EQEEAKKEEKTETVSKEEKVDAVAPNAP 117
Query 351 LTKEQEAENSKVYAGPAVRKLARELGVVLAQVKASGEHGRLMKEDIYAYVKQRLT-APVA 409
+ + N +V A P+VRK ARE GV + V+ +G++GR++KEDI A++ AP A
Sbjct 118 AAEAEAGPNRRVIAMPSVRKYAREKGVDIRLVQGTGKNGRVLKEDIDAFLAGGAKPAPAA 177
Query 410 APKAAAAAVASGLPTLPDFSAFGGVEEKTLTRLQQVSIPQLSLNNFIPQVTQFDLADITE 469
A + AA A A T +F EK + ++ + + P VT D AD+T+
Sbjct 178 AEEKAAPAAAKPATTEGEFPE---TREKMSGIRRAIAKAMVHSKHTAPHVTLMDEADVTK 234
Query 470 LEAWRNDLKGNFKKEGISLTIMAFIIKAVAHLLKEEREFAGHLSDDGKSVLLRKEIHMGI 529
L A R K ++GI LT + +++KA+ L+E + D+ + ++ + ++GI
Sbjct 235 LVAHRKKFKAIAAEKGIKLTFLPYVVKALVSALREYPVLNTSIDDETEEIIQKHYYNIGI 294
Query 530 AVATPDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQGANFTISSLGAIGG 589
A T GL VPV+++ D+K I +A E+ + +KARD KL+P +++GA+ TI+++G+ GG
Sbjct 295 AADTDRGLLVPVIKHADRKPIFALAQEINELAEKARDGKLTPGEMKGASCTITNIGSAGG 354
Query 590 TAFTPLVNWPQVAILGISPATMQPVWNGKDFDPRLMLPLSLSYDHRVINGADAARFTNKL 649
FTP++N P+VAILGI +P+ + ML LSLS+DHR+I+GA A + N +
Sbjct 355 QWFTPVINHPEVAILGIGRIAEKPIVRDGEIVAAPMLALSLSFDHRMIDGATAQKALNHI 414
Query 650 TKLLQDIRSLLI 661
+LL D LL+
Sbjct 415 KRLLSDPELLLM 426
Score = 64.7 bits (156), Expect = 4e-14
Identities = 69/234 (29%), Positives = 102/234 (44%), Gaps = 35/234 (15%)
Query 2 QVKTPDIG--VDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSL 59
+ K PDIG + + + + VK GD ++E+D L +++DKA VE+PS G V ILV
Sbjct 4 EFKLPDIGEGIHEGEIVKWFVKPGDEVNEDDVLCEVQNDKAVVEIPSPVKGKVLEILVPE 63
Query 60 GDEVSEGTTLIELESGDNTDKTESESAPAQTEVKAETPVEQVAPQETKPATSTSAASSVV 119
G + G TLI L++ + T Q E K E E V+ +E A + +A ++
Sbjct 64 GTVATVGQTLITLDAPGYENMT--FKGQEQEEAKKEEKTETVSKEEKVDAVAPNAPAAEA 121
Query 120 EVQVPDIGVEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAGD 179
E G + +A + SV E + L V GT K G
Sbjct 122 EA-----GPNRRVIA--MPSVRKYAREKGVDIRL------------VQGT-----GKNGR 157
Query 180 TIQEGVLLLKVKTAGASNAAPAKQEAVVPTAAPVATK-AETQAETPAVQSAPAG 232
++E + AG + APA E AAP A K A T+ E P + +G
Sbjct 158 VLKEDI---DAFLAGGAKPAPAAAE---EKAAPAAAKPATTEGEFPETREKMSG 205
Score = 55.1 bits (131), Expect = 4e-11
Identities = 69/278 (25%), Positives = 109/278 (39%), Gaps = 46/278 (17%)
Query 120 EVQVPDIG--VEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKA 177
E ++PDIG + + + + V GDE+ E+D L +++DKA VE+PS V G + I V
Sbjct 4 EFKLPDIGEGIHEGEIVKWFVKPGDEVNEDDVLCEVQNDKAVVEIPSPVKGKVLEILVPE 63
Query 178 GDTIQEGVLLLKVKTAGASNAAPAKQEAVVPTAAPVATKAETQAETPAVQSAPAGAVDVL 237
G G L+ + G N QE K E + ET + + VD +
Sbjct 64 GTVATVGQTLITLDAPGYENMTFKGQE-------QEEAKKEEKTETVSKEE----KVDAV 112
Query 238 VPDLGVDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQDVK 297
P+ A AE ++ S+ +K I + G
Sbjct 113 APN-----APAAEAEAGPNRRVIAMPSVRKYAREKGV------------DIRLVQGTGKN 155
Query 298 EGILLVTVEAEGAVASAPKAPVAKAEAAPA---PAAQKAEAP------------AAKVET 342
+L ++A A + P A+ +AAPA PA + E P AK
Sbjct 156 GRVLKEDIDAFLAGGAKPAPAAAEEKAAPAAAKPATTEGEFPETREKMSGIRRAIAKAMV 215
Query 343 APQAGADKLTKEQEAENSKVYA-GPAVRKLARELGVVL 379
+ A +T EA+ +K+ A + +A E G+ L
Sbjct 216 HSKHTAPHVTLMDEADVTKLVAHRKKFKAIAAEKGIKL 253
>P21883 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Bacillus subtilis (strain
168)]
Length=442
Score = 217 bits (552), Expect = 8e-67
Identities = 141/442 (32%), Positives = 238/442 (54%), Gaps = 16/442 (4%)
Query 233 AVDVLVPDLG--VDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHV 290
A + +PD+G + + + + V D++ +D+ + V++DKA VE+PS V G V + V
Sbjct 2 AFEFKLPDIGEGIHEGEIVKWFVKPNDEVDEDDVLAEVQNDKAVVEIPSPVKGKVLELKV 61
Query 291 KAGQDVKEGILLVTVEAEG----AVASAPKAPVAKAEAAPAPAAQKAEAPAAKVETAPQA 346
+ G G ++T +A G + ++ AK EA A+ + A + + A
Sbjct 62 EEGTVATVGQTIITFDAPGYEDLQFKGSDESDDAKTEAQVQSTAEAGQDVAKEEQAQEPA 121
Query 347 GADKLTKEQEAE---NSKVYAGPAVRKLARELGVVLAQVKASGEHGRLMKEDIYAYV--- 400
A ++ +AE N +V A P+VRK ARE GV + +V SG +GR++KEDI ++V
Sbjct 122 KATGAGQQDQAEVDPNKRVIAMPSVRKYAREKGVDIRKVTGSGNNGRVVKEDIDSFVNGG 181
Query 401 -KQRLTAPVAAPKAAAAAVASGLPTLPDFSAFGGVEEKTLTRLQQVSIPQLSLNNFIPQV 459
++ AAP+ AA A+ P+ F EK + ++ ++ + P V
Sbjct 182 AQEAAPQETAAPQETAAKPAAA--PAPE-GEFPETREKMSGIRKAIAKAMVNSKHTAPHV 238
Query 460 TQFDLADITELEAWRNDLKGNFKKEGISLTIMAFIIKAVAHLLKEEREFAGHLSDDGKSV 519
T D D+T L A R K +GI LT + +++KA+ LK+ + D V
Sbjct 239 TLMDEVDVTNLVAHRKQFKQVAADQGIKLTYLPYVVKALTSALKKFPVLNTSIDDKTDEV 298
Query 520 LLRKEIHMGIAVATPDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQGANF 579
+ + ++GIA T GL VPV++N D+K++ +I+ E+ + KAR+ KL+P +++GA+
Sbjct 299 IQKHYFNIGIAADTEKGLLVPVVKNADRKSVFEISDEINGLATKAREGKLAPAEMKGASC 358
Query 580 TISSLGAIGGTAFTPLVNWPQVAILGISPATMQPVWNGKDFDPRLMLPLSLSYDHRVING 639
TI+++G+ GG FTP++N P+VAILGI + + + +L LSLS+DHR+I+G
Sbjct 359 TITNIGSAGGQWFTPVINHPEVAILGIGRIAEKAIVRDGEIVAAPVLALSLSFDHRMIDG 418
Query 640 ADAARFTNKLTKLLQDIRSLLI 661
A A N + +LL D + +L+
Sbjct 419 ATAQNALNHIKRLLNDPQLILM 440
Score = 58.2 bits (139), Expect = 5e-12
Identities = 84/322 (26%), Positives = 132/322 (41%), Gaps = 65/322 (20%)
Query 2 QVKTPDIG--VDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSL 59
+ K PDIG + + + + VK D + E+D L +++DKA VE+PS G V + V
Sbjct 4 EFKLPDIGEGIHEGEIVKWFVKPNDEVDEDDVLAEVQNDKAVVEIPSPVKGKVLELKVEE 63
Query 60 GDEVSEGTTLIELESGDNTD---KTESESAPAQTEVKAETPVE---QVAPQE--TKPATS 111
G + G T+I ++ D K ES A+TE + ++ E VA +E +PA +
Sbjct 64 GTVATVGQTIITFDAPGYEDLQFKGSDESDDAKTEAQVQSTAEAGQDVAKEEQAQEPAKA 123
Query 112 TSAA-SSVVEVQVPDIGVEKATVAELLVSVGDEIAE-----NDSLVLLESDKASVEVPST 165
T A EV + +V + G +I + N+ V+ E ++ S
Sbjct 124 TGAGQQDQAEVDPNKRVIAMPSVRKYAREKGVDIRKVTGSGNNGRVVKE------DIDSF 177
Query 166 VSGTIESIEVKAGDTIQEGVLLLKVKTAGASNAAPAKQEAVVPTAAPVATKAETQAETPA 225
V+G GA AAP + TAAP T A+ PA
Sbjct 178 VNG-------------------------GAQEAAPQE------TAAPQETAAK-----PA 201
Query 226 VQSAPAGAVDVLVPDLGVDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIV 285
AP G + + A+A+ +VN K T ++ E V+V + V+
Sbjct 202 AAPAPEGEFPETREKMSGIRKAIAKAMVN--SKHTAPHVTLMDE-----VDVTNLVAHRK 254
Query 286 KAIHVKAGQDVKEGILLVTVEA 307
+ V A Q +K L V+A
Sbjct 255 QFKQVAADQGIKLTYLPYVVKA 276
Score = 57.4 bits (137), Expect = 8e-12
Identities = 59/227 (26%), Positives = 100/227 (44%), Gaps = 30/227 (13%)
Query 120 EVQVPDIG--VEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKA 177
E ++PDIG + + + + V DE+ E+D L +++DKA VE+PS V G + ++V+
Sbjct 4 EFKLPDIGEGIHEGEIVKWFVKPNDEVDEDDVLAEVQNDKAVVEIPSPVKGKVLELKVEE 63
Query 178 GDTIQEGVLLL--------KVKTAGASNAAPAKQEAVVPTAAPVA--TKAETQAETPAVQ 227
G G ++ ++ G+ + AK EA V + A E QA+ PA +
Sbjct 64 GTVATVGQTIITFDAPGYEDLQFKGSDESDDAKTEAQVQSTAEAGQDVAKEEQAQEPA-K 122
Query 228 SAPAGAVDVLVPDLGVDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKA 287
+ AG D ++ +K +A V K +++ + D V +VK
Sbjct 123 ATGAGQQD--QAEVDPNKRVIAMPSVR---KYAREKGV-----DIRKVTGSGNNGRVVK- 171
Query 288 IHVKAGQDVKEGILLVTVEAEGAVASAPKAPVAKAEAAPAPAAQKAE 334
+D+ + EA +AP+ AK AAPAP + E
Sbjct 172 ------EDIDSFVNGGAQEAAPQETAAPQETAAKPAAAPAPEGEFPE 212
>Q59821 Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex [Staphylococcus aureus]
Length=430
Score = 212 bits (540), Expect = 3e-65
Identities = 142/438 (32%), Positives = 231/438 (53%), Gaps = 20/438 (5%)
Query 233 AVDVLVPDLG--VDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHV 290
A + +PD+G + + + + V GD I +D+ + V++DK+ VE+PS VSG V+ + V
Sbjct 2 AFEFRLPDIGEGIHEGEIVKWFVKAGDTIEEDDVLAEVQNDKSVVEIPSPVSGTVEEVMV 61
Query 291 KAGQDVKEGILLVTVEAEGAVASAPKAPVAKAEAAPAPAAQKAEAPAAKVETAPQAGADK 350
+ G G ++V ++A A K + + PA K EAPA + A Q
Sbjct 62 EEGTVAVVGDVIVKIDAPDAEDMQFKGHDDDSSSKEEPA--KEEAPAEQAPVATQT---- 115
Query 351 LTKEQEAENSKVYAGPAVRKLARELGVVLAQVKASGEHGRLMKEDIYAYVKQRLTAPVAA 410
E+ EN V A P+VRK ARE GV + V SG++GR+ KED+ AY+ AP A+
Sbjct 116 ---EEVDENRTVKAMPSVRKYAREKGVNIKAVSGSGKNGRITKEDVDAYLNGG--APTAS 170
Query 411 PKAAAAAVASGLPTLPDFSAFGGVE-------EKTLTRLQQVSIPQLSLNNFIPQVTQFD 463
++A +A + P A +E EK + ++ ++ + P VT D
Sbjct 171 NESADSATNEEVAETPAAPAAVSLEGDFPETTEKIPAMRRAIAKAMVNSKHTAPHVTLMD 230
Query 464 LADITELEAWRNDLKGNFKKEGISLTIMAFIIKAVAHLLKEEREFAGHLSDDGKSVLLRK 523
D+ L R K ++G LT + +++KA+ LK+ +++ ++ +
Sbjct 231 EIDVQALWDHRKKFKEIAAEQGTKLTFLPYVVKALVSALKKYPALNTSFNEEAGEIVHKH 290
Query 524 EIHMGIAVATPDGLTVPVLRNPDQKTIKQIAVELGVIGQKARDKKLSPKDLQGANFTISS 583
++GIA T GL VPV+++ D+K+I QI+ E+ + KARD KL+ +++GA TIS+
Sbjct 291 YWNIGIAADTDRGLLVPVVKHADRKSIFQISDEINELAVKARDGKLTADEMKGATCTISN 350
Query 584 LGAIGGTAFTPLVNWPQVAILGISPATMQPVWNGKDFDPRLMLPLSLSYDHRVINGADAA 643
+G+ GG FTP++N P+VAILGI +P+ + +L LSLS+DHR I+GA
Sbjct 351 IGSAGGQWFTPVINHPEVAILGIGRIAQKPIVKDGEIVAAPVLALSLSFDHRQIDGATGQ 410
Query 644 RFTNKLTKLLQDIRSLLI 661
N + +LL + LL+
Sbjct 411 NAMNHIKRLLNNPELLLM 428
Score = 68.6 bits (166), Expect = 2e-15
Identities = 52/159 (33%), Positives = 82/159 (52%), Gaps = 20/159 (13%)
Query 120 EVQVPDIG--VEKATVAELLVSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKA 177
E ++PDIG + + + + V GD I E+D L +++DK+ VE+PS VSGT+E + V+
Sbjct 4 EFRLPDIGEGIHEGEIVKWFVKAGDTIEEDDVLAEVQNDKSVVEIPSPVSGTVEEVMVEE 63
Query 178 GDTIQEGVLLLKVKTAGA-------------SNAAPAKQEAVVPTAAPVATKAETQAETP 224
G G +++K+ A S PAK+EA APVAT+ E E
Sbjct 64 GTVAVVGDVIVKIDAPDAEDMQFKGHDDDSSSKEEPAKEEAPA-EQAPVATQTEEVDENR 122
Query 225 AVQSAPAGAVDVLVPDLGVDKAAVAEILVNVGDKITKDE 263
V++ P +V + GV+ AV+ N +ITK++
Sbjct 123 TVKAMP--SVRKYAREKGVNIKAVSGSGKN--GRITKED 157
Score = 63.2 bits (152), Expect = 1e-13
Identities = 36/112 (32%), Positives = 62/112 (55%), Gaps = 7/112 (6%)
Query 2 QVKTPDIG--VDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSL 59
+ + PDIG + + + + VK GDTI E+D L +++DK+ VE+PS SG V+ ++V
Sbjct 4 EFRLPDIGEGIHEGEIVKWFVKAGDTIEEDDVLAEVQNDKSVVEIPSPVSGTVEEVMVEE 63
Query 60 GDEVSEGTTLIELESGDNTDKT----ESESAPAQTEVKAETPVEQVAPQETK 107
G G ++++++ D D + +S+ + K E P EQ AP T+
Sbjct 64 GTVAVVGDVIVKIDAPDAEDMQFKGHDDDSSSKEEPAKEEAPAEQ-APVATQ 114
Lambda K H a alpha
0.311 0.128 0.340 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 3912115
Database: 7a4dff882605ad93f8d0131d5e0b5888.SwissProt.fasta
Posted date: Jun 2, 2024 4:25 PM
Number of letters in database: 7,215
Number of sequences in database: 14
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
