BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 057e7619d0811620b47446b0601a6cfc.SwissProt.fasta
12 sequences; 2,434 total letters
Query= ACIAD0080
Length=188
Score E
Sequences producing significant alignments: (Bits) Value
P37780 dTDP-4-dehydrorhamnose 3,5-epimerase [Shigella flexneri] 235 1e-83
P26394 dTDP-4-dehydrorhamnose 3,5-epimerase [Salmonella typhimuri... 211 3e-74
Q9HU21 dTDP-4-dehydrorhamnose 3,5-epimerase [Pseudomonas aerugino... 203 4e-71
P37745 dTDP-4-dehydrorhamnose 3,5-epimerase [Escherichia coli (st... 201 3e-70
O27818 dTDP-4-dehydrorhamnose 3,5-epimerase [Methanothermobacter ... 179 3e-61
P37763 dTDP-4-dehydrorhamnose 3,5-epimerase [Neisseria gonorrhoeae] 182 1e-60
P55468 dTDP-4-dehydrorhamnose 3,5-epimerase [Sinorhizobium fredii... 157 1e-52
P9WH10 dTDP-4-dehydrorhamnose 3,5-epimerase [Mycobacterium tuberc... 112 5e-35
P9WH11 dTDP-4-dehydrorhamnose 3,5-epimerase [Mycobacterium tuberc... 112 5e-35
P29783 dTDP-4-dehydrorhamnose 3,5-epimerase [Streptomyces griseus] 107 3e-33
Q331R1 dTDP-4-dehydro-6-deoxyglucose 3-epimerase [Streptomyces sp] 100 3e-30
Q5SFD1 dTDP-4-dehydro-6-deoxyglucose 3-epimerase [Streptomyces bi... 99.8 4e-30
>P37780 dTDP-4-dehydrorhamnose 3,5-epimerase [Shigella flexneri]
Length=181
Score = 235 bits (600), Expect = 1e-83
Identities = 113/187 (60%), Positives = 146/187 (78%), Gaps = 7/187 (4%)
Query 1 MNIIETKIKDLLIFEPRVFGDDRGWFMESFNQQVFEQALTERGLDIPKFVQDNHSFSKKG 60
MN+I+T+I D+LIFEP+VFGD+RG+FMESFNQ+VFE+A+ + +FVQDNHS S KG
Sbjct 1 MNVIKTEIPDVLIFEPKVFGDERGFFMESFNQKVFEEAVGRK----VEFVQDNHSKSTKG 56
Query 61 VLRGLHYQLNPHAQGKLVRVVQGRAWDVAVDIRENSSTFGEWVGVELTADNHKQFWIPAG 120
VLRGLHYQL P+AQGKLVR V G +DVAVDIR++S TFG+WVGV L+A+N +Q WIP G
Sbjct 57 VLRGLHYQLEPYAQGKLVRCVVGEVFDVAVDIRKSSPTFGKWVGVNLSAENKRQLWIPEG 116
Query 121 FAHGFIALEDNTQFLYKTTDYYSKECERSIVWNDETINIEWPIEKDLEILLTDKDRLAPQ 180
FAHGF L D +F+YKT ++YSK ER I+W+D++INIEWP++ LL+DKD +
Sbjct 117 FAHGFCVLSDEAEFVYKTNNFYSKMQERGILWSDKSINIEWPVQNP---LLSDKDINGQK 173
Query 181 LIQADKF 187
+ AD F
Sbjct 174 FVDADYF 180
>P26394 dTDP-4-dehydrorhamnose 3,5-epimerase [Salmonella typhimurium
(strain LT2 / SGSC1412 / ATCC 700720)]
Length=183
Score = 211 bits (538), Expect = 3e-74
Identities = 106/184 (58%), Positives = 131/184 (71%), Gaps = 6/184 (3%)
Query 1 MNIIETKIKDLLIFEPRVFGDDRGWFMESFNQQVFEQALTERGLDIPKFVQDNHSFSKKG 60
M +I+T I D+LI EP+VFGD+RG+F ES+NQQ FE+ + + FVQDNHS SKK
Sbjct 2 MIVIKTAIPDVLILEPKVFGDERGFFFESYNQQTFEELIGRK----VTFVQDNHSKSKKN 57
Query 61 VLRGLHYQLNPHAQGKLVRVVQGRAWDVAVDIRENSSTFGEWVGVELTADNHKQFWIPAG 120
VLRGLH+Q +AQGKLVR G +DVAVDIR+ S TFG+WVGV L+A+N +Q WIP G
Sbjct 58 VLRGLHFQRGENAQGKLVRCAVGEVFDVAVDIRKESPTFGQWVGVNLSAENKRQLWIPEG 117
Query 121 FAHGFIALEDNTQFLYKTTDYYSKECERSIVWNDETINIEWPIEKDLEILLTDKDRLAPQ 180
FAHGF+ L + +FLYK T+YYS E SI+WNDE I IEWP + E L+ KD AP
Sbjct 118 FAHGFVTLSEYAEFLYKATNYYSPSSEGSILWNDEAIGIEWPFSQLPE--LSAKDAAAPL 175
Query 181 LIQA 184
L QA
Sbjct 176 LDQA 179
>Q9HU21 dTDP-4-dehydrorhamnose 3,5-epimerase [Pseudomonas aeruginosa
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847
/ LMG 12228 / 1C / PRS 101 / PAO1)]
Length=181
Score = 203 bits (517), Expect = 4e-71
Identities = 101/187 (54%), Positives = 128/187 (68%), Gaps = 7/187 (4%)
Query 1 MNIIETKIKDLLIFEPRVFGDDRGWFMESFNQQVFEQALTERGLDIPKFVQDNHSFSKKG 60
M I D+++FEPRVFGDDRG+F ES+NQ+ FE+A FVQDNHS S +G
Sbjct 1 MKATRLAIPDVILFEPRVFGDDRGFFFESYNQRAFEEACGHP----VSFVQDNHSRSARG 56
Query 61 VLRGLHYQLNPHAQGKLVRVVQGRAWDVAVDIRENSSTFGEWVGVELTADNHKQFWIPAG 120
VLRGLHYQ+ AQGKLVR G +DVAVD+R S TFG+WVG L+A+N +Q WIPAG
Sbjct 57 VLRGLHYQIR-QAQGKLVRATLGEVFDVAVDLRRGSPTFGQWVGERLSAENKRQMWIPAG 115
Query 121 FAHGFIALEDNTQFLYKTTDYYSKECERSIVWNDETINIEWPIEKDLEILLTDKDRLAPQ 180
FAHGF+ L + +FLYKTTD+++ E ER IVWND + I+WP++ LL++KDR
Sbjct 116 FAHGFVVLSEYAEFLYKTTDFWAPEHERCIVWNDPELKIDWPLQD--APLLSEKDRQGKA 173
Query 181 LIQADKF 187
AD F
Sbjct 174 FADADCF 180
>P37745 dTDP-4-dehydrorhamnose 3,5-epimerase [Escherichia coli
(strain K12)]
Length=185
Score = 201 bits (512), Expect = 3e-70
Identities = 103/175 (59%), Positives = 123/175 (70%), Gaps = 6/175 (3%)
Query 1 MNIIETKIKDLLIFEPRVFGDDRGWFMESFNQQVFEQALTERGLDIPKFVQDNHSFSKKG 60
MN+I T+I+D+LI EPRVFGDDRG+F ESFNQ FE L G + FVQDNHS S K
Sbjct 1 MNVIRTEIEDVLILEPRVFGDDRGFFYESFNQSAFEHIL---GYPV-SFVQDNHSRSSKN 56
Query 61 VLRGLHYQLNPHAQGKLVRVVQGRAWDVAVDIRENSSTFGEWVGVELTADNHKQFWIPAG 120
VLRGLH+Q +AQ KLVR G +DVAVDIR NS +FG+WVGV L+ADN +Q WIP G
Sbjct 57 VLRGLHFQRGEYAQDKLVRCTHGAVFDVAVDIRPNSVSFGKWVGVLLSADNKQQLWIPKG 116
Query 121 FAHGFIALEDNTQFLYKTTDYYSKECERSIVWNDETINIEWPIEKDLEILLTDKD 175
FAHGF+ L D +F YKTT+YY E + I WNDE I I+WP L +L+ KD
Sbjct 117 FAHGFLVLSDIAEFQYKTTNYYHPESDCGICWNDERIAIDWPQTSGL--ILSPKD 169
>O27818 dTDP-4-dehydrorhamnose 3,5-epimerase [Methanothermobacter
thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044
/ NBRC 100330 / Delta H)]
Length=185
Score = 179 bits (453), Expect = 3e-61
Identities = 85/173 (49%), Positives = 123/173 (71%), Gaps = 6/173 (3%)
Query 4 IETKIKDLLIFEPRVFGDDRGWFMESFNQQVFEQALTERGLDIPKFVQDNHSFSKKGVLR 63
I+T + +I EP V+ D+RG+FME+FN+ +F+ E GL++ +FVQDN S S +GVLR
Sbjct 7 IKTSLDGAIIIEPEVYTDERGYFMETFNEAIFQ----ENGLEV-RFVQDNESMSVRGVLR 61
Query 64 GLHYQLNPHAQGKLVRVVQGRAWDVAVDIRENSSTFGEWVGVELTADNHKQFWIPAGFAH 123
GLH+Q QGKLVRV++G +DVAVD+R+NS T+GEW GV L+ +N ++F+IP GFAH
Sbjct 62 GLHFQ-REKPQGKLVRVIRGEIFDVAVDLRKNSDTYGEWTGVRLSDENRREFFIPEGFAH 120
Query 124 GFIALEDNTQFLYKTTDYYSKECERSIVWNDETINIEWPIEKDLEILLTDKDR 176
GF+AL D YK T+ Y E + I W+D I I+WP+E ++++++KDR
Sbjct 121 GFLALSDECIVNYKCTELYHPEYDSGIPWDDPDIGIDWPLEMVDDLIISEKDR 173
>P37763 dTDP-4-dehydrorhamnose 3,5-epimerase [Neisseria gonorrhoeae]
Length=328
Score = 182 bits (461), Expect = 1e-60
Identities = 93/186 (50%), Positives = 122/186 (66%), Gaps = 8/186 (4%)
Query 1 MNIIETKIKDLLIFEPRVFGDDRGWFMESFNQQVFEQALTERGLDIPKFVQDNHSFSKKG 60
M+II+T + D+ + +P+VF D RG+FME+F F++ + +R FVQ+NHS S KG
Sbjct 1 MDIIDTALPDVKLLKPQVFTDGRGFFMETFRDGWFKENIADR-----TFVQENHSNSSKG 55
Query 61 VLRGLHYQLNPHAQGKLVRVVQGRAWDVAVDIRENSSTFGEWVGVELTADNHKQFWIPAG 120
VLRGLHYQ + QGKLVRVV G +DVAVD+RE S TFG+W G L+A N Q WIP G
Sbjct 56 VLRGLHYQTE-NTQGKLVRVVVGEVFDVAVDMREGSPTFGKWAGATLSAQNRYQLWIPEG 114
Query 121 FAHGFIALEDNTQFLYKTTDYYSKECERSIVWNDETINIEWPIEKDLEILLTDKDRLAPQ 180
FAHGF L D + +YK TDYY+ E E+ ++WND I I WP++ LL+ KD
Sbjct 115 FAHGFCVLGDAAEVVYKCTDYYNPETEQVLIWNDPAIGIGWPLQ--TAPLLSPKDLAGKT 172
Query 181 LIQADK 186
QA+K
Sbjct 173 WAQAEK 178
>P55468 dTDP-4-dehydrorhamnose 3,5-epimerase [Sinorhizobium fredii
(strain NBRC 101917 / NGR234)]
Length=195
Score = 157 bits (396), Expect = 1e-52
Identities = 81/177 (46%), Positives = 111/177 (63%), Gaps = 8/177 (5%)
Query 8 IKDLLIFEPRVFGDDRGWFMESFNQQVFEQALTERGLDIPKFVQDNHSFSKK-GVLRGLH 66
I ++ + PR FGD RG+F E F ++ F + + + GL VQDN S S + G +RGLH
Sbjct 16 IAEVKLIRPRKFGDCRGYFSEVFREKWFRKNVADVGL-----VQDNESLSAQIGTVRGLH 70
Query 67 YQLNPHAQGKLVRVVQGRAWDVAVDIRENSSTFGEWVGVELTADNHKQFWIPAGFAHGFI 126
+QL P AQGKLVR +G +DVAVD+R S T+G+WV EL+ +N Q W+PAGFAHGF+
Sbjct 71 FQLEPFAQGKLVRCTRGALFDVAVDVRVGSPTYGKWVSAELSQENGAQLWVPAGFAHGFM 130
Query 127 ALEDNTQFLYKTTDYYSKECERSIVWNDETINIEWPIEKDLEILLTDKDRLAPQLIQ 183
L+ +T YK T YS E +R + W+D I I WP K +L++KD P L +
Sbjct 131 TLKADTVISYKVTAPYSAEHDRGLKWDDPAIGINWP--KMTTYVLSEKDSSQPSLCE 185
>P9WH10 dTDP-4-dehydrorhamnose 3,5-epimerase [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=202
Score = 112 bits (280), Expect = 5e-35
Identities = 63/164 (38%), Positives = 87/164 (53%), Gaps = 4/164 (2%)
Query 16 PRVFGDDRGWFMESFNQQVFEQALTERGLDIPKFVQDNHSFSKKGVLRGLHYQLNPHAQG 75
P + D RG F E F +A LD+ Q N S S GVLRGLH+ P +Q
Sbjct 16 PTIHVDSRGLFFEWLTDHGF-RAFAGHSLDVR---QVNCSVSSAGVLRGLHFAQLPPSQA 71
Query 76 KLVRVVQGRAWDVAVDIRENSSTFGEWVGVELTADNHKQFWIPAGFAHGFIALEDNTQFL 135
K V V G +DV VDIRE S TFG W V L + + ++ G AHGF+AL+DN+ +
Sbjct 72 KYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVM 131
Query 136 YKTTDYYSKECERSIVWNDETINIEWPIEKDLEILLTDKDRLAP 179
Y + Y+ + E +I D T+ ++WP+ L+D+D AP
Sbjct 132 YLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAP 175
>P9WH11 dTDP-4-dehydrorhamnose 3,5-epimerase [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=202
Score = 112 bits (280), Expect = 5e-35
Identities = 63/164 (38%), Positives = 87/164 (53%), Gaps = 4/164 (2%)
Query 16 PRVFGDDRGWFMESFNQQVFEQALTERGLDIPKFVQDNHSFSKKGVLRGLHYQLNPHAQG 75
P + D RG F E F +A LD+ Q N S S GVLRGLH+ P +Q
Sbjct 16 PTIHVDSRGLFFEWLTDHGF-RAFAGHSLDVR---QVNCSVSSAGVLRGLHFAQLPPSQA 71
Query 76 KLVRVVQGRAWDVAVDIRENSSTFGEWVGVELTADNHKQFWIPAGFAHGFIALEDNTQFL 135
K V V G +DV VDIRE S TFG W V L + + ++ G AHGF+AL+DN+ +
Sbjct 72 KYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVM 131
Query 136 YKTTDYYSKECERSIVWNDETINIEWPIEKDLEILLTDKDRLAP 179
Y + Y+ + E +I D T+ ++WP+ L+D+D AP
Sbjct 132 YLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAP 175
>P29783 dTDP-4-dehydrorhamnose 3,5-epimerase [Streptomyces griseus]
Length=200
Score = 107 bits (268), Expect = 3e-33
Identities = 64/172 (37%), Positives = 92/172 (53%), Gaps = 7/172 (4%)
Query 15 EPRVFGDDRGWFMESFNQQVFEQALTERGLDIPKFVQDNHSFSKKGVLRGLHYQLNPHAQ 74
E R F DDRG F E ++ + AL G D P Q N S S++GVLRG+H+ P +Q
Sbjct 13 ETRAFADDRGEFQELYSARSLRGAL---GYD-PGVAQVNRSVSRRGVLRGVHFAQLPPSQ 68
Query 75 GKLVRVVQGRAWDVAVDIRENSSTFGEWVGVELTADNHKQFWIPAGFAHGFIALEDNTQF 134
K V + G DV VDIR S T+ W V L D H+ ++ AG H F+AL D+
Sbjct 69 AKYVTCLSGAVLDVVVDIRTGSPTYRAWEAVRLD-DPHRSLYVEAGLGHSFMALTDDAVV 127
Query 135 LYKTTDYYSKECERSIVWNDETINIEWPIEKDLEILLTDKDRLAPQLIQADK 186
+Y T+ Y+ E + D + I WP +E +L++KDR AP + + ++
Sbjct 128 VYLTSQGYAAGREHGVHPLDPDLGIAWP--DGIEPVLSEKDRQAPGIAEMER 177
>Q331R1 dTDP-4-dehydro-6-deoxyglucose 3-epimerase [Streptomyces
sp]
Length=196
Score = 100 bits (248), Expect = 3e-30
Identities = 62/172 (36%), Positives = 88/172 (51%), Gaps = 6/172 (3%)
Query 15 EPRVFGDDRGWFMESFNQQVFEQALTERGLDIPKFVQDNHSFSKKGVLRGLHYQLNPHAQ 74
EP + D RG E F + F Q G D P Q N + S +G LRG+HY P Q
Sbjct 13 EPVIHSDHRGRSHEWFRGERFRQTF---GHDFP-VAQVNVAVSHRGALRGIHYTEIPPGQ 68
Query 75 GKLVRVVQGRAWDVAVDIRENSSTFGEWVGVELTADNHKQFWIPAGFAHGFIALEDNTQF 134
K V+G DV VD+R S TFG W V + A+ + ++ AG F++L D+
Sbjct 69 AKYSVCVRGAGLDVIVDVRIGSPTFGRWEIVPMDAERNTAVYLAAGLGRAFLSLTDDATL 128
Query 135 LYKTTDYYSKECERSIVWNDETINIEWPIEKDLEILLTDKDRLAPQLIQADK 186
+Y + Y+ E E S+ D + I WP D+E LL+D+D+ AP L A++
Sbjct 129 VYLCSSGYAPEREHSVNPLDPDLGIVWP--ADIEPLLSDRDKNAPTLATAER 178
>Q5SFD1 dTDP-4-dehydro-6-deoxyglucose 3-epimerase [Streptomyces
bikiniensis]
Length=196
Score = 99.8 bits (247), Expect = 4e-30
Identities = 62/172 (36%), Positives = 87/172 (51%), Gaps = 6/172 (3%)
Query 15 EPRVFGDDRGWFMESFNQQVFEQALTERGLDIPKFVQDNHSFSKKGVLRGLHYQLNPHAQ 74
EP + D RG E F + F QA G D P Q N + S +G LRG+HY P Q
Sbjct 13 EPVIHSDHRGRSHEWFRGESFRQAF---GHDFP-VAQVNVAVSHRGALRGIHYTEIPPGQ 68
Query 75 GKLVRVVQGRAWDVAVDIRENSSTFGEWVGVELTADNHKQFWIPAGFAHGFIALEDNTQF 134
K V+G DV VD+R S TFG W V + A+ + ++ AG F++L D+
Sbjct 69 AKYSVCVRGAGLDVVVDVRIGSPTFGRWEIVPMDAERNTAVYLTAGLGRAFLSLTDDATL 128
Query 135 LYKTTDYYSKECERSIVWNDETINIEWPIEKDLEILLTDKDRLAPQLIQADK 186
+Y + Y+ E S+ D + I WP D+E LL+D+D AP L A++
Sbjct 129 VYLCSSGYAPAREHSVNPLDPDLGIAWP--DDIEPLLSDRDENAPTLATAER 178
Lambda K H a alpha
0.324 0.140 0.442 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 300490
Database: 057e7619d0811620b47446b0601a6cfc.SwissProt.fasta
Posted date: May 20, 2024 4:58 AM
Number of letters in database: 2,434
Number of sequences in database: 12
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
