BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 6015587ece3954c140776076ca7736b6.SwissProt.fasta
12 sequences; 2,722 total letters
Query= ACIAD0633
Length=193
Score E
Sequences producing significant alignments: (Bits) Value
Q1LJ80 Cobalamin adenosyltransferase [Cupriavidus metallidurans (... 168 6e-57
O34899 Corrinoid adenosyltransferase [Bacillus subtilis (strain 1... 127 1e-40
P53523 Corrinoid adenosyltransferase [Mycobacterium leprae (strai... 115 4e-36
P9WP99 Corrinoid adenosyltransferase [Mycobacterium tuberculosis ... 113 2e-35
P9WP98 Corrinoid adenosyltransferase [Mycobacterium tuberculosis ... 113 2e-35
P64804 Corrinoid adenosyltransferase [Mycobacterium bovis (strain... 113 2e-35
Q9D273 Corrinoid adenosyltransferase MMAB [Mus musculus] 102 8e-31
Q58D49 Corrinoid adenosyltransferase MMAB [Bos taurus] 102 2e-30
P45515 Corrinoid adenosyltransferase [Citrobacter freundii] 99.8 3e-30
Q96EY8 Corrinoid adenosyltransferase MMAB [Homo sapiens] 101 3e-30
Q8ZNR5 Corrinoid adenosyltransferase PduO [Salmonella typhimurium... 88.6 9e-25
B1VB74 Corrinoid adenosyltransferase PduO [Citrobacter freundii] 85.5 1e-23
>Q1LJ80 Cobalamin adenosyltransferase [Cupriavidus metallidurans
(strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)]
Length=184
Score = 168 bits (425), Expect = 6e-57
Identities = 96/186 (52%), Positives = 122/186 (66%), Gaps = 6/186 (3%)
Query 1 MGHRLSKIYTRTGDSGTTGLGDGSRVAKDDLRITALGDVDELNAILGVLRAQIASSTLQT 60
MG+RLSKI TRTGD+GTTGLGDGSRV K+ LRI A+GDVDELN+ +G+L +
Sbjct 1 MGNRLSKIATRTGDAGTTGLGDGSRVGKNSLRIVAIGDVDELNSHIGLLLTE-PDLPEDV 59
Query 61 KSAWDKNLSLIQHWLFDLGGEVCIPNYHLLQPVSIDFLEKEIDQMNEELPMLKEFILPSG 120
++A L IQH LFDLGGE+ IP Y LL+ + L+ + N LP L EFILP G
Sbjct 60 RAA----LLHIQHDLFDLGGELSIPGYTLLKAPQVAQLDDWLAHYNAALPRLAEFILPGG 115
Query 121 SLTCSYAHQARAVCRRAERSLIAVQQRDQNIQTTALQLLNRLSDWLFVASRMLQRESGGS 180
S + AH R VCRRAER+L+ + + + Q LNRLSD LFV +R+L R GGS
Sbjct 116 SRPAAQAHICRTVCRRAERALVELGAAEA-LNEAPRQYLNRLSDLLFVLARVLNRAGGGS 174
Query 181 EMLWQK 186
++LWQ+
Sbjct 175 DVLWQR 180
>O34899 Corrinoid adenosyltransferase [Bacillus subtilis (strain
168)]
Length=193
Score = 127 bits (318), Expect = 1e-40
Identities = 76/186 (41%), Positives = 112/186 (60%), Gaps = 11/186 (6%)
Query 7 KIYTRTGDSGTTGLGDGSRVAKDDLRITALGDVDELNAILGVLRAQIASST-LQTKSAWD 65
K+YT+TGD G TGL G R KD LR+ + G +DELN+ +G+ A+++ + +A
Sbjct 2 KLYTKTGDKGQTGLV-GGRTDKDSLRVESYGTIDELNSFIGLALAELSGQPGFEDLTA-- 58
Query 66 KNLSLIQHWLFDLGGEVCI----PNYHLLQPVSIDFLEKEIDQMNEELPMLKEFILPSGS 121
L IQH LFD GG++ I +Y L + S+ FLE ID E P LK+FILP GS
Sbjct 59 -ELLTIQHELFDCGGDLAIVTERKDYKLTEE-SVSFLETRIDAYTAEAPELKKFILPGGS 116
Query 122 LTCSYAHQARAVCRRAERSLIAVQQRDQNIQTTALQLLNRLSDWLFVASRMLQRESGGSE 181
S H AR + RRAER ++A+ + + I T L+ LNRLSD+ F A+R++ SG +
Sbjct 117 KCASLLHIARTITRRAERRVVAL-MKSEEIHETVLRYLNRLSDYFFAAARVVNARSGIGD 175
Query 182 MLWQKN 187
+ ++++
Sbjct 176 VEYERS 181
>P53523 Corrinoid adenosyltransferase [Mycobacterium leprae (strain
TN)]
Length=191
Score = 115 bits (287), Expect = 4e-36
Identities = 81/196 (41%), Positives = 104/196 (53%), Gaps = 19/196 (10%)
Query 1 MGHRLSKIYTRTGDSGTTGLGDGSRVAKDDLRITALGDVDELNAILGVLRAQIASSTLQT 60
M L++IYTRTGD+GTTGL D SRVAK DLR+ A D DE N+ +GV A T
Sbjct 1 MAIHLTRIYTRTGDNGTTGLSDFSRVAKTDLRLVAYADCDETNSAIGVALALGNPDQKIT 60
Query 61 KSAWDKNLSLIQHWLFDLGGEVCI--------PNYHLLQ--PVSIDFLEKEIDQMNEELP 110
L IQ+ LFD G ++ P Y L+ ID LE+ D N LP
Sbjct 61 DV-----LQQIQNDLFDAGADLSTPMQDSVRNPEYPQLRITQTHIDRLEEWCDTYNTPLP 115
Query 111 MLKEFILPSGSLTCSYAHQARAVCRRAERSL-IAVQQRDQNIQTTALQLLNRLSDWLFVA 169
L F+LP GS + H AR V RRAERS AV+ + + LNRLSD LF+
Sbjct 116 TLNSFVLPGGSPLSALLHVARTVARRAERSAWAAVEAHPGVVSMLPAKYLNRLSDLLFIL 175
Query 170 SRMLQRESGGSEMLWQ 185
SR+ + G+++LW+
Sbjct 176 SRV---ANTGNDVLWR 188
>P9WP99 Corrinoid adenosyltransferase [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=193
Score = 113 bits (283), Expect = 2e-35
Identities = 79/193 (41%), Positives = 98/193 (51%), Gaps = 16/193 (8%)
Query 1 MGHRLSKIYTRTGDSGTTGLGDGSRVAKDDLRITALGDVDELNAILGVLRAQIASSTLQT 60
M L++IYTRTGD GTTGL D SRVAK D R+ A D DE NA +G A T T
Sbjct 1 MAVHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQIT 60
Query 61 KSAWDKNLSLIQHWLFDLGGEVCIPNYH-------LLQPVSIDFLEKEIDQMNEELPMLK 113
L IQ+ LFD G ++ P + ID LE D N LP LK
Sbjct 61 DV-----LRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALK 115
Query 114 EFILPSGSLTCSYAHQARAVCRRAERSL-IAVQQRDQNIQTTALQLLNRLSDWLFVASRM 172
F+LP GS + H AR V RRAERS AV + + + LNRLSD LF+ SR+
Sbjct 116 SFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRV 175
Query 173 LQRESGGSEMLWQ 185
+ ++LW+
Sbjct 176 ANPD---GDVLWR 185
>P9WP98 Corrinoid adenosyltransferase [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=193
Score = 113 bits (283), Expect = 2e-35
Identities = 79/193 (41%), Positives = 98/193 (51%), Gaps = 16/193 (8%)
Query 1 MGHRLSKIYTRTGDSGTTGLGDGSRVAKDDLRITALGDVDELNAILGVLRAQIASSTLQT 60
M L++IYTRTGD GTTGL D SRVAK D R+ A D DE NA +G A T T
Sbjct 1 MAVHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQIT 60
Query 61 KSAWDKNLSLIQHWLFDLGGEVCIPNYH-------LLQPVSIDFLEKEIDQMNEELPMLK 113
L IQ+ LFD G ++ P + ID LE D N LP LK
Sbjct 61 DV-----LRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALK 115
Query 114 EFILPSGSLTCSYAHQARAVCRRAERSL-IAVQQRDQNIQTTALQLLNRLSDWLFVASRM 172
F+LP GS + H AR V RRAERS AV + + + LNRLSD LF+ SR+
Sbjct 116 SFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRV 175
Query 173 LQRESGGSEMLWQ 185
+ ++LW+
Sbjct 176 ANPD---GDVLWR 185
>P64804 Corrinoid adenosyltransferase [Mycobacterium bovis (strain
ATCC BAA-935 / AF2122/97)]
Length=193
Score = 113 bits (283), Expect = 2e-35
Identities = 79/193 (41%), Positives = 98/193 (51%), Gaps = 16/193 (8%)
Query 1 MGHRLSKIYTRTGDSGTTGLGDGSRVAKDDLRITALGDVDELNAILGVLRAQIASSTLQT 60
M L++IYTRTGD GTTGL D SRVAK D R+ A D DE NA +G A T T
Sbjct 1 MAVHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQIT 60
Query 61 KSAWDKNLSLIQHWLFDLGGEVCIPNYH-------LLQPVSIDFLEKEIDQMNEELPMLK 113
L IQ+ LFD G ++ P + ID LE D N LP LK
Sbjct 61 DV-----LRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALK 115
Query 114 EFILPSGSLTCSYAHQARAVCRRAERSL-IAVQQRDQNIQTTALQLLNRLSDWLFVASRM 172
F+LP GS + H AR V RRAERS AV + + + LNRLSD LF+ SR+
Sbjct 116 SFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRV 175
Query 173 LQRESGGSEMLWQ 185
+ ++LW+
Sbjct 176 ANPD---GDVLWR 185
>Q9D273 Corrinoid adenosyltransferase MMAB [Mus musculus]
Length=237
Score = 102 bits (255), Expect = 8e-31
Identities = 68/193 (35%), Positives = 100/193 (52%), Gaps = 14/193 (7%)
Query 4 RLSKIYTRTGDSGTTGLGDGSRVAKDDLRITALGDVDELNAILGVLRAQIASSTLQTKSA 63
++ KIYT+TGD G + G R KDD A+G DEL++ +G + +
Sbjct 48 KIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFAMELVT----EKGHM 103
Query 64 WDKNLSLIQHWLFDLGGEVCIPNY-----HL----LQPVSIDFLEKEIDQMNEELPMLKE 114
+ + L IQ L D+G + P HL Q + LE+ ID+ + +LP LK
Sbjct 104 FAEELQKIQCMLQDVGSALATPRSSAREAHLKHTAFQEGPVLELERWIDKYSSQLPPLKA 163
Query 115 FILPSGSLTCSYAHQARAVCRRAERSLIAVQQRDQNIQTTALQLLNRLSDWLFVASRMLQ 174
FILPSG + S H RAVCRRAER ++ + Q + A + LNRLSD+LF +R
Sbjct 164 FILPSGGKSSSALHFCRAVCRRAERRVVPLVQMGETDANVA-KFLNRLSDYLFTVARYAA 222
Query 175 RESGGSEMLWQKN 187
+ G E +++K+
Sbjct 223 MKEGSQEKIYKKH 235
>Q58D49 Corrinoid adenosyltransferase MMAB [Bos taurus]
Length=241
Score = 102 bits (253), Expect = 2e-30
Identities = 69/193 (36%), Positives = 101/193 (52%), Gaps = 14/193 (7%)
Query 4 RLSKIYTRTGDSGTTGLGDGSRVAKDDLRITALGDVDELNAILGVLRAQIASSTLQTKSA 63
++ KIYT+TGD G + G R +KDD A+G DEL++ +G IA +
Sbjct 48 KVPKIYTKTGDKGFSSTFTGERRSKDDQVFEAVGTTDELSSAIGFAMELIA----EKGHP 103
Query 64 WDKNLSLIQHWLFDLGGEVCIPNY-----HL----LQPVSIDFLEKEIDQMNEELPMLKE 114
+ + L IQ L D+G + P HL + I LE+ ID+ + +LP L
Sbjct 104 FVEELQKIQCSLQDVGSALATPRSSAREAHLKHATFEAGPILELEQWIDKYSRQLPPLTA 163
Query 115 FILPSGSLTCSYAHQARAVCRRAERSLIAVQQRDQNIQTTALQLLNRLSDWLFVASRMLQ 174
FILPSG + S H RAVCRRAER ++ + Q + ++ LNRLSD+LF +R
Sbjct 164 FILPSGGKSSSALHFCRAVCRRAERRVVPLVQTGET-DANVVKFLNRLSDYLFTLARYTA 222
Query 175 RESGGSEMLWQKN 187
+ G E +++KN
Sbjct 223 MKEGNPEKIYKKN 235
>P45515 Corrinoid adenosyltransferase [Citrobacter freundii]
Length=176
Score = 99.8 bits (247), Expect = 3e-30
Identities = 68/172 (40%), Positives = 95/172 (55%), Gaps = 13/172 (8%)
Query 7 KIYTRTGDSGTTGLGDGSRVAKDDLRITALGDVDELNAILGVLRAQIASSTLQTKSAWDK 66
+IYTRTGD+GTT L GSR+ KDD+R+ A G VDEL + LGV A + L+ +
Sbjct 3 RIYTRTGDNGTTALFGGSRIDKDDIRVEAYGTVDELISQLGVCYASTRQAELR------Q 56
Query 67 NLSLIQHWLFDLGGEVCIPNYHL------LQPVSIDFLEKEIDQMNEELPMLKEFILPSG 120
L +Q LF LG E+ L + I LE+ ID+ + LKEF++P
Sbjct 57 ELHAMQKMLFVLGAELASDQKGLTRLKQRIGEEDIQALEQLIDRNMAQSGPLKEFVIPGK 116
Query 121 SLTCSYAHQARAVCRRAERSLIAVQQRDQNIQTTALQLLNRLSDWLFVASRM 172
+L + H AR + RR ER LIA+ R ++ A + +NRLSD LF +R+
Sbjct 117 NLASAQLHVARTLTRRLERILIAM-GRTLTLRDEARRYINRLSDALFSMARI 167
>Q96EY8 Corrinoid adenosyltransferase MMAB [Homo sapiens]
Length=250
Score = 101 bits (252), Expect = 3e-30
Identities = 68/193 (35%), Positives = 95/193 (49%), Gaps = 14/193 (7%)
Query 4 RLSKIYTRTGDSGTTGLGDGSRVAKDDLRITALGDVDELNAILGVLRAQIASSTLQTKSA 63
R+ KIYT+TGD G + G R KDD A+G DEL++ +G + +
Sbjct 54 RIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALELVT----EKGHT 109
Query 64 WDKNLSLIQHWLFDLGGEVCIP---------NYHLLQPVSIDFLEKEIDQMNEELPMLKE 114
+ + L IQ L D+G + P Y + I LE+ ID+ +LP L
Sbjct 110 FAEELQKIQCTLQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKYTSQLPPLTA 169
Query 115 FILPSGSLTCSYAHQARAVCRRAERSLIAVQQRDQNIQTTALQLLNRLSDWLFVASRMLQ 174
FILPSG S H RAVCRRAER ++ + Q + A + LNRLSD+LF +R
Sbjct 170 FILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVA-KFLNRLSDYLFTLARYAA 228
Query 175 RESGGSEMLWQKN 187
+ G E ++ KN
Sbjct 229 MKEGNQEKIYMKN 241
>Q8ZNR5 Corrinoid adenosyltransferase PduO [Salmonella typhimurium
(strain LT2 / SGSC1412 / ATCC 700720)]
Length=336
Score = 88.6 bits (218), Expect = 9e-25
Identities = 61/170 (36%), Positives = 82/170 (48%), Gaps = 13/170 (8%)
Query 8 IYTRTGDSGTTGLGDGSRVAKDDLRITALGDVDELNAILGVLRAQIASSTLQTKSAWDKN 67
IYTRTGD+GTT L G RV+K R+ A G +DELNA L + A +T
Sbjct 3 IYTRTGDAGTTSLFTGQRVSKTHPRVEAYGTLDELNAALSLCACAAADENHRTL------ 56
Query 68 LSLIQHWLFDLGGEVC------IPNYHLLQPVSIDFLEKEIDQMNEELPMLKEFILPSGS 121
L IQ LF E+ P + I LE ID+ + L FILP
Sbjct 57 LEAIQQQLFWFSAELASDSEQPSPKQRYISSEEISALEAAIDRAMARVEPLHSFILPGRC 116
Query 122 LTCSYAHQARAVCRRAERSLIAVQQRDQNIQTTALQLLNRLSDWLFVASR 171
S H AR + RRAER L+ + + N++ ++ +NRLSD L+ +R
Sbjct 117 EAASRLHFARTLARRAERRLVEL-ATEVNVRQVLMRYINRLSDCLYALAR 165
Score = 15.4 bits (28), Expect = 9.7
Identities = 5/11 (45%), Positives = 6/11 (55%), Gaps = 0/11 (0%)
Query 178 GGSEMLWQKNI 188
GG LW+ I
Sbjct 294 GGGYALWRDGI 304
>B1VB74 Corrinoid adenosyltransferase PduO [Citrobacter freundii]
Length=335
Score = 85.5 bits (210), Expect = 1e-23
Identities = 60/167 (36%), Positives = 84/167 (50%), Gaps = 7/167 (4%)
Query 8 IYTRTGDSGTTGLGDGSRVAKDDLRITALGDVDELNAILGVLRAQIASSTLQTKSAWDKN 67
IYTRTGD+GTT L G RV+K R+ A G +DELNA L + A+ Q + + N
Sbjct 3 IYTRTGDAGTTALFTGQRVSKTHPRVEAYGTLDELNAALSL--CVCAAKNPQHRQLLE-N 59
Query 68 LSLIQHWL---FDLGGEVCIPNYHLLQPVSIDFLEKEIDQMNEELPMLKEFILPSGSLTC 124
+ L W E P + I LE ID +P L+ FILP S
Sbjct 60 IQLQLFWFSAELASESEQPAPEQRYISSEEIAALEAAIDTAMGRVPPLRSFILPGRSEAA 119
Query 125 SYAHQARAVCRRAERSLIAVQQRDQNIQTTALQLLNRLSDWLFVASR 171
S H AR + RRAER L+ + + +++ ++ +NRLSD L+ +R
Sbjct 120 SRLHFARTLARRAERRLVEL-STEISVRHVLMRYINRLSDCLYALAR 165
Score = 15.4 bits (28), Expect = 9.7
Identities = 4/11 (36%), Positives = 7/11 (64%), Gaps = 0/11 (0%)
Query 178 GGSEMLWQKNI 188
GG LW++ +
Sbjct 293 GGGYALWREGL 303
Lambda K H a alpha
0.322 0.136 0.402 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 351230
Database: 6015587ece3954c140776076ca7736b6.SwissProt.fasta
Posted date: Jun 2, 2024 5:30 AM
Number of letters in database: 2,722
Number of sequences in database: 12
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
