BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 78e50b12f50545ce919cb3e42220437a.SwissProt.fasta
25 sequences; 9,886 total letters
Query= ACIAD0784
Length=370
Score E
Sequences producing significant alignments: (Bits) Value
P25196 Nodulation protein NolF [Rhizobium meliloti (strain 1021)] 95.9 4e-25
P75830 Macrolide export protein MacA [Escherichia coli (strain K12)] 70.1 2e-16
P64177 Macrolide export protein MacA [Shigella flexneri] 68.9 6e-16
P64176 Macrolide export protein MacA [Escherichia coli O157:H7] 68.9 6e-16
B4T9U0 Multidrug resistance protein MdtA [Salmonella heidelberg (... 68.9 7e-16
P24180 Multidrug export protein AcrE [Escherichia coli (strain K12)] 67.8 1e-15
B7NCB0 Multidrug resistance protein MdtA [Escherichia coli O17:K5... 67.8 2e-15
B7NQB2 Multidrug resistance protein MdtA [Escherichia coli O7:K1 ... 67.8 2e-15
B5YUD2 Multidrug resistance protein MdtA [Escherichia coli O157:H... 67.0 3e-15
Q8X7J5 Multidrug resistance protein MdtA [Escherichia coli O157:H7] 67.0 3e-15
B7UTB2 Multidrug resistance protein MdtA [Escherichia coli O127:H... 67.0 3e-15
A7ZNP7 Multidrug resistance protein MdtA [Escherichia coli O139:H... 67.0 3e-15
P76397 Multidrug resistance protein MdtA [Escherichia coli (strai... 67.0 3e-15
Q8Z5F8 Multidrug resistance protein MdtA [Salmonella typhi] 66.6 4e-15
C0Q1F4 Multidrug resistance protein MdtA [Salmonella paratyphi C ... 66.6 4e-15
B1LNW7 Multidrug resistance protein MdtA [Escherichia coli (strai... 66.6 4e-15
B7ME86 Multidrug resistance protein MdtA [Escherichia coli O45:K1... 66.6 4e-15
Q83KI5 Putative multidrug resistance protein MdtA [Shigella flexn... 66.2 4e-15
P0AE06 Multidrug efflux pump subunit AcrA [Escherichia coli (stra... 63.5 4e-14
P52599 Probable multidrug resistance protein EmrK [Escherichia co... 63.2 5e-14
Q9KJC3 Antibiotic efflux pump periplasmic linker protein ArpA [Ps... 59.7 6e-13
Q9WWZ9 Toluene efflux pump periplasmic linker protein TtgA [Pseud... 59.7 6e-13
Q88N30 Probable efflux pump periplasmic linker TtgA [Pseudomonas ... 59.3 8e-13
P0C069 Multidrug/solvent efflux pump periplasmic linker protein M... 59.3 8e-13
P27303 Multidrug export protein EmrA [Escherichia coli (strain K12)] 59.3 8e-13
>P25196 Nodulation protein NolF [Rhizobium meliloti (strain 1021)]
Length=367
Score = 95.9 bits (237), Expect = 4e-25
Identities = 68/270 (25%), Positives = 131/270 (49%), Gaps = 7/270 (3%)
Query 42 IELIAQDLIAVRTGELQTKIPFTGTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLV 101
IEL D+ ++ ++ G++ + +S++ ++V++T ++ +G+ V +LV
Sbjct 39 IELAKADVSTAVRQDMANEVRIVGSLTPIRRSTLTSRVSSTIIELPVQIGDVVNAGDLLV 98
Query 102 RLNNQDNVARLAQARANLASAQAQAELAHNLMLRKKRLLDQGFIS---RVEYEQSQVDYK 158
R + + +A + AQ ELA ++ R RL ++G S R+ +D +
Sbjct 99 RFERGALESAVTGRKAEADALSAQTELAEAVLERNTRLGERGAASEATRLAALADVLDLR 158
Query 159 GQLETANAQKANLDIALKADQDGIIRSPLTGVITKRQVEPGQTVSAGQTLFEIVDPKQLE 218
QL + A+ ++ + +L + +R+ GVI R VE GQTV L IV+ +LE
Sbjct 159 AQLRSKQAEVSDAERSLSHAE---VRAEFGGVIAARSVEEGQTVPLNTQLMTIVELNRLE 215
Query 219 IQAKLPLEQQAALKTGKTIQFNIQG-ETQSRSARLSRISPVADQASRQIEFFATPSDVIQ 277
+ A +P + ++ ++++ ++G ++ S ++RISP AD SR + F +
Sbjct 216 VDAGVPTSRIPLIRLKQSVELTVEGFPGRTFSGEVARISPTADAGSRAVRVFIAVDNEEG 275
Query 278 SLSIGAFVEGFIINQDQIQGQIIPLDSIQN 307
L G F G + DQ +P SI++
Sbjct 276 LLRGGMFTIGDLRVDDQKDVIALPAASIRH 305
>P75830 Macrolide export protein MacA [Escherichia coli (strain
K12)]
Length=371
Score = 70.1 bits (170), Expect = 2e-16
Identities = 78/326 (24%), Positives = 156/326 (48%), Gaps = 29/326 (9%)
Query 50 IAVRTGELQTKIPFTGTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVL-----VRLN 104
+ VR G+LQ + TG + A+ + + AQV+ ++ +G+ V K+Q+L +
Sbjct 39 LIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAE 98
Query 105 NQ--DNVARLAQARANLASAQAQAELAHNLMLRKKRLLDQGFISRVEYEQSQVDY---KG 159
NQ + A L + RA A+A+ +LA R++RL +S+ + + + + +
Sbjct 99 NQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTKAVSQQDLDTAATEMAVKQA 158
Query 160 QLETANAQ----KANLDIALKADQDGIIRSPLTGVITKRQVEPGQTVSAGQ---TLFEIV 212
Q+ T +AQ +A+LD A I +P+ G +T+ GQTV A Q + +
Sbjct 159 QIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLA 218
Query 213 DPKQLEIQAKLPLEQQAALKTGKTIQFNIQGETQSR-SARLSRISPVADQASRQIEFFA- 270
D + ++A++ LK G+ F + G+ +R ++ + P ++ + I ++A
Sbjct 219 DMSAMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYYAR 278
Query 271 ----TPSDVIQSLSIGAFVEGFIINQDQIQGQIIPLDSIQNL--DHQPFVWVIRQQKIHK 324
P+ +++ L + A V I D IPL ++ + D++ V ++R + +
Sbjct 279 FEVPNPNGLLR-LDMTAQVH--IQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETRE 335
Query 325 INIQVLEKRFADNQAIVKGLQSSDQI 350
+ + + D + IVKGL++ D++
Sbjct 336 REVTIGARNDTDVE-IVKGLEAGDEV 360
>P64177 Macrolide export protein MacA [Shigella flexneri]
Length=371
Score = 68.9 bits (167), Expect = 6e-16
Identities = 78/326 (24%), Positives = 155/326 (48%), Gaps = 29/326 (9%)
Query 50 IAVRTGELQTKIPFTGTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVL-----VRLN 104
+ VR G+LQ + TG + A+ + + AQV+ ++ +G+ V K+Q+L +
Sbjct 39 LIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAE 98
Query 105 NQ--DNVARLAQARANLASAQAQAELAHNLMLRKKRLLDQGFISRVEYEQSQVDY---KG 159
NQ + A L + RA A+A+ +LA R++RL +S + + + + +
Sbjct 99 NQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSLQDLDTAATEMAVKQA 158
Query 160 QLETANAQ----KANLDIALKADQDGIIRSPLTGVITKRQVEPGQTVSAGQ---TLFEIV 212
Q+ T +AQ +A+LD A I +P+ G +T+ GQTV A Q + +
Sbjct 159 QIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLA 218
Query 213 DPKQLEIQAKLPLEQQAALKTGKTIQFNIQGETQSR-SARLSRISPVADQASRQIEFFA- 270
D + ++A++ LK G+ F + G+ +R ++ + P ++ + I ++A
Sbjct 219 DMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYYAR 278
Query 271 ----TPSDVIQSLSIGAFVEGFIINQDQIQGQIIPLDSIQNL--DHQPFVWVIRQQKIHK 324
P+ +++ L + A V I D IPL ++ + D++ V ++R + +
Sbjct 279 FEVPNPNGLLR-LDMTAQVH--IQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETRE 335
Query 325 INIQVLEKRFADNQAIVKGLQSSDQI 350
+ + + D + IVKGL++ D++
Sbjct 336 REVTIGARNDTDVE-IVKGLEAGDEV 360
>P64176 Macrolide export protein MacA [Escherichia coli O157:H7]
Length=371
Score = 68.9 bits (167), Expect = 6e-16
Identities = 78/326 (24%), Positives = 155/326 (48%), Gaps = 29/326 (9%)
Query 50 IAVRTGELQTKIPFTGTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVL-----VRLN 104
+ VR G+LQ + TG + A+ + + AQV+ ++ +G+ V K+Q+L +
Sbjct 39 LIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAE 98
Query 105 NQ--DNVARLAQARANLASAQAQAELAHNLMLRKKRLLDQGFISRVEYEQSQVDY---KG 159
NQ + A L + RA A+A+ +LA R++RL +S + + + + +
Sbjct 99 NQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSLQDLDTAATEMAVKQA 158
Query 160 QLETANAQ----KANLDIALKADQDGIIRSPLTGVITKRQVEPGQTVSAGQ---TLFEIV 212
Q+ T +AQ +A+LD A I +P+ G +T+ GQTV A Q + +
Sbjct 159 QIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLA 218
Query 213 DPKQLEIQAKLPLEQQAALKTGKTIQFNIQGETQSR-SARLSRISPVADQASRQIEFFA- 270
D + ++A++ LK G+ F + G+ +R ++ + P ++ + I ++A
Sbjct 219 DMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYYAR 278
Query 271 ----TPSDVIQSLSIGAFVEGFIINQDQIQGQIIPLDSIQNL--DHQPFVWVIRQQKIHK 324
P+ +++ L + A V I D IPL ++ + D++ V ++R + +
Sbjct 279 FEVPNPNGLLR-LDMTAQVH--IQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETRE 335
Query 325 INIQVLEKRFADNQAIVKGLQSSDQI 350
+ + + D + IVKGL++ D++
Sbjct 336 REVTIGARNDTDVE-IVKGLEAGDEV 360
>B4T9U0 Multidrug resistance protein MdtA [Salmonella heidelberg
(strain SL476)]
Length=413
Score = 68.9 bits (167), Expect = 7e-16
Identities = 67/298 (22%), Positives = 126/298 (42%), Gaps = 15/298 (5%)
Query 65 GTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQA 124
GT+ A N +++++V ++ G+ V +L +++ LAQA+ LA A
Sbjct 79 GTVTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPSQFKVALAQAQGQLAKDNA 138
Query 125 QAELAHNLMLRKKRLLDQGFISRVEYEQSQVDYKGQLETANAQKANLDIALKADQDGIIR 184
A + R ++L +SR E + Q T A +AN+ A I
Sbjct 139 TLANARRDLARYQQLAKTNLVSRQELDAQQALVNETQGTIKADEANVASAQLQLDWSRIT 198
Query 185 SPLTGVITKRQVEPGQTVSAGQT--LFEIVDPKQLEIQAKLPLEQQA----ALKTGKTIQ 238
+P++G + +QV+ G +S+ T + I +++ LP A A K GKT+
Sbjct 199 APVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLPESDIATVVQAQKAGKTLV 258
Query 239 FNIQGETQSRSAR---LSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQDQI 295
T S L + D + I+ A ++ +L FV ++ +
Sbjct 259 VEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQ 318
Query 296 QGQIIPLDSIQNLDHQPFVWVIR-QQKIHKINIQVLEKRFADNQAIV--KGLQSSDQI 350
++P ++Q + FVWV+ + + K+ +++ DNQ +V GL + D++
Sbjct 319 NAVVVPAAAVQMGNEGHFVWVLNDENNVSKMRVKI---GIQDNQNVVISAGLSAGDRV 373
>P24180 Multidrug export protein AcrE [Escherichia coli (strain
K12)]
Length=385
Score = 67.8 bits (164), Expect = 1e-15
Identities = 74/316 (23%), Positives = 124/316 (39%), Gaps = 18/316 (6%)
Query 52 VRTGELQTKIPFTGTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVAR 111
V+T L+ K G A + ++ QV+ N G V Q L +++ A
Sbjct 44 VKTAPLEVKTELPGRTNAYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQAN 103
Query 112 LAQARANLASAQAQAELAHNLMLRKKRLLDQGFISRVEYEQSQVDYKGQLETANAQKANL 171
A+ LA ++A A +AH + R L+ +IS+ EY+Q+ D + A KA +
Sbjct 104 YDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAKATV 163
Query 172 DIALKADQDGIIRSPLTGVITKRQVEPGQTVSAGQTLFEIVDPKQLE------------- 218
+ A + +P++G I K V G V+ GQT E+ +QL+
Sbjct 164 ESARINLAYTKVTAPISGRIGKSTVTEGALVTNGQTT-ELATVQQLDPIYVDVTQSSNDF 222
Query 219 IQAKLPLEQQAALKTGKTIQFNI---QGETQSRSARLSRISPVADQASRQIEFFATPSDV 275
++ K +EQ K T + G+T L D+++ I A +
Sbjct 223 MRLKQSVEQGNLHKENATSNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLRAVFPNP 282
Query 276 IQSLSIGAFVEGFIINQDQIQGQIIPLDSIQNLDH-QPFVWVIRQQKIHKINIQVLEKRF 334
+L G FV I Q +IP + V ++ + + V +
Sbjct 283 QHTLLPGMFVRARIDEGVQPDAILIPQQGVSRTPRGDATVLIVNDKSQVEARPVVASQAI 342
Query 335 ADNQAIVKGLQSSDQI 350
D I +GL+S DQ+
Sbjct 343 GDKWLISEGLKSGDQV 358
>B7NCB0 Multidrug resistance protein MdtA [Escherichia coli O17:K52:H18
(strain UMN026 / ExPEC)]
Length=415
Score = 67.8 bits (164), Expect = 2e-15
Identities = 66/300 (22%), Positives = 131/300 (44%), Gaps = 19/300 (6%)
Query 65 GTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQA 124
GTI A N +++++V ++ G+ V +L ++ LAQA+ LA +A
Sbjct 80 GTITAANTVTVRSRVDGQLIALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKA 139
Query 125 QAELAHNLMLRKKRLLDQGFISRVEYEQSQV---DYKGQLETANAQKANLDIALKADQDG 181
A + R ++L+ +SR E + Q + +G ++ A A+ + L +
Sbjct 140 TLANARRDLARYQQLVKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSR-- 197
Query 182 IIRSPLTGVITKRQVEPGQTVSAGQT--LFEIVDPKQLEIQAKLPLEQQA----ALKTGK 235
I +P+ G + +QV+ G +S+G T + I +++ LP A A K GK
Sbjct 198 -ITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGK 256
Query 236 TIQFNIQGETQSR---SARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQ 292
+ T S+ L + D + I+ A ++ +L FV ++
Sbjct 257 PLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVD 316
Query 293 DQIQGQIIPLDSIQNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIV--KGLQSSDQI 350
+ +IP ++Q + FVWV+ + +K++ ++ D+Q +V G+ + D++
Sbjct 317 TEQNAVVIPTAALQMGNEGHFVWVLNSE--NKVSKHLVTPGIQDSQKVVIRAGISAGDRV 374
>B7NQB2 Multidrug resistance protein MdtA [Escherichia coli O7:K1
(strain IAI39 / ExPEC)]
Length=415
Score = 67.8 bits (164), Expect = 2e-15
Identities = 66/300 (22%), Positives = 131/300 (44%), Gaps = 19/300 (6%)
Query 65 GTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQA 124
GTI A N +++++V ++ G+ V +L ++ LAQA+ LA +A
Sbjct 80 GTITAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKA 139
Query 125 QAELAHNLMLRKKRLLDQGFISRVEYEQSQV---DYKGQLETANAQKANLDIALKADQDG 181
A + R ++L+ +SR E + Q + +G ++ A A+ + L +
Sbjct 140 TLANARRDLARYQQLVKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSR-- 197
Query 182 IIRSPLTGVITKRQVEPGQTVSAGQT--LFEIVDPKQLEIQAKLPLEQQA----ALKTGK 235
I +P+ G + +QV+ G +S+G T + I +++ LP A A K GK
Sbjct 198 -ITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLLFTLPESDIATVVQAQKAGK 256
Query 236 TIQFNIQGETQSR---SARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQ 292
+ T S+ L + D + I+ A ++ +L FV ++
Sbjct 257 PLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVD 316
Query 293 DQIQGQIIPLDSIQNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIV--KGLQSSDQI 350
+ +IP ++Q + FVWV+ + +K++ ++ D+Q +V G+ + D++
Sbjct 317 TEQNAVVIPTAALQMGNEGHFVWVLNSE--NKVSKHLVTPGIQDSQKVVIRAGISAGDRV 374
>B5YUD2 Multidrug resistance protein MdtA [Escherichia coli O157:H7
(strain EC4115 / EHEC)]
Length=415
Score = 67.0 bits (162), Expect = 3e-15
Identities = 66/300 (22%), Positives = 130/300 (43%), Gaps = 19/300 (6%)
Query 65 GTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQA 124
GTI A N +++++V ++ G+ V +L ++ LAQA+ LA +A
Sbjct 80 GTITAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKA 139
Query 125 QAELAHNLMLRKKRLLDQGFISRVEYEQSQV---DYKGQLETANAQKANLDIALKADQDG 181
A + R ++L +SR E + Q + +G ++ A A+ + L +
Sbjct 140 TLTNARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSR-- 197
Query 182 IIRSPLTGVITKRQVEPGQTVSAGQT--LFEIVDPKQLEIQAKLPLEQQA----ALKTGK 235
I +P+ G + +QV+ G +S+G T + I +++ LP A A K GK
Sbjct 198 -ITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLLFTLPESDIATVVQAQKAGK 256
Query 236 TIQFNIQGETQSR---SARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQ 292
+ T S+ L + D + I+ A ++ +L FV ++
Sbjct 257 PLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVD 316
Query 293 DQIQGQIIPLDSIQNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIV--KGLQSSDQI 350
+ +IP ++Q + FVWV+ + +K++ ++ D+Q +V G+ + D++
Sbjct 317 TEQNAVVIPTAALQMGNEGHFVWVLNSE--NKVSKHLVTPGIQDSQKVVIRAGISAGDRV 374
>Q8X7J5 Multidrug resistance protein MdtA [Escherichia coli O157:H7]
Length=415
Score = 67.0 bits (162), Expect = 3e-15
Identities = 66/300 (22%), Positives = 130/300 (43%), Gaps = 19/300 (6%)
Query 65 GTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQA 124
GTI A N +++++V ++ G+ V +L ++ LAQA+ LA +A
Sbjct 80 GTITAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKA 139
Query 125 QAELAHNLMLRKKRLLDQGFISRVEYEQSQV---DYKGQLETANAQKANLDIALKADQDG 181
A + R ++L +SR E + Q + +G ++ A A+ + L +
Sbjct 140 TLTNARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSR-- 197
Query 182 IIRSPLTGVITKRQVEPGQTVSAGQT--LFEIVDPKQLEIQAKLPLEQQA----ALKTGK 235
I +P+ G + +QV+ G +S+G T + I +++ LP A A K GK
Sbjct 198 -ITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLLFTLPESDIATVVQAQKAGK 256
Query 236 TIQFNIQGETQSR---SARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQ 292
+ T S+ L + D + I+ A ++ +L FV ++
Sbjct 257 PLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVD 316
Query 293 DQIQGQIIPLDSIQNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIV--KGLQSSDQI 350
+ +IP ++Q + FVWV+ + +K++ ++ D+Q +V G+ + D++
Sbjct 317 TEQNAVVIPTAALQMGNEGHFVWVLNSE--NKVSKHLVTPGIQDSQKVVIRAGISAGDRV 374
>B7UTB2 Multidrug resistance protein MdtA [Escherichia coli O127:H6
(strain E2348/69 / EPEC)]
Length=415
Score = 67.0 bits (162), Expect = 3e-15
Identities = 66/300 (22%), Positives = 130/300 (43%), Gaps = 19/300 (6%)
Query 65 GTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQA 124
GTI A N +++++V ++ G+ V +L ++ LAQA+ LA +A
Sbjct 80 GTITAANTVTVRSRVDGQLIALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKA 139
Query 125 QAELAHNLMLRKKRLLDQGFISRVEYEQSQV---DYKGQLETANAQKANLDIALKADQDG 181
A + R ++L +SR E + Q + +G ++ A A+ + L +
Sbjct 140 TLANARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSR-- 197
Query 182 IIRSPLTGVITKRQVEPGQTVSAGQT--LFEIVDPKQLEIQAKLPLEQQA----ALKTGK 235
I +P+ G + +QV+ G +S+G T + I +++ LP A A K GK
Sbjct 198 -ITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGK 256
Query 236 TIQFNIQGETQSR---SARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQ 292
+ T S+ L + D + I+ A ++ +L FV ++
Sbjct 257 PLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVD 316
Query 293 DQIQGQIIPLDSIQNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIV--KGLQSSDQI 350
+ +IP ++Q + FVWV+ + +K++ ++ D+Q +V G+ + D++
Sbjct 317 TEQNAVVIPTAALQMGNEGHFVWVLNSE--NKVSKHLVTPGIQDSQKVVIRAGISAGDRV 374
>A7ZNP7 Multidrug resistance protein MdtA [Escherichia coli O139:H28
(strain E24377A / ETEC)]
Length=415
Score = 67.0 bits (162), Expect = 3e-15
Identities = 66/300 (22%), Positives = 130/300 (43%), Gaps = 19/300 (6%)
Query 65 GTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQA 124
GTI A N +++++V ++ G+ V +L ++ LAQA+ LA +A
Sbjct 80 GTITAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKA 139
Query 125 QAELAHNLMLRKKRLLDQGFISRVEYEQSQV---DYKGQLETANAQKANLDIALKADQDG 181
A + R ++L +SR E + Q + +G ++ A A+ + L +
Sbjct 140 TLANARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSR-- 197
Query 182 IIRSPLTGVITKRQVEPGQTVSAGQT--LFEIVDPKQLEIQAKLPLEQQA----ALKTGK 235
I +P+ G + +QV+ G +S+G T + I +++ LP A A K GK
Sbjct 198 -ITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGK 256
Query 236 TIQFNIQGETQSR---SARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQ 292
+ T S+ L + D + I+ A ++ +L FV ++
Sbjct 257 PLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVD 316
Query 293 DQIQGQIIPLDSIQNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIV--KGLQSSDQI 350
+ +IP ++Q + FVWV+ + +K++ ++ D+Q +V G+ + D++
Sbjct 317 TEQNAVVIPTAALQMGNEGHFVWVLNSE--NKVSKHLVTPGIQDSQKVVIRAGISAGDRV 374
>P76397 Multidrug resistance protein MdtA [Escherichia coli (strain
K12)]
Length=415
Score = 67.0 bits (162), Expect = 3e-15
Identities = 66/300 (22%), Positives = 130/300 (43%), Gaps = 19/300 (6%)
Query 65 GTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQA 124
GTI A N +++++V ++ G+ V +L ++ LAQA+ LA +A
Sbjct 80 GTITAANTVTVRSRVDGQLIALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKA 139
Query 125 QAELAHNLMLRKKRLLDQGFISRVEYEQSQV---DYKGQLETANAQKANLDIALKADQDG 181
A + R ++L +SR E + Q + +G ++ A A+ + L +
Sbjct 140 TLANARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSR-- 197
Query 182 IIRSPLTGVITKRQVEPGQTVSAGQT--LFEIVDPKQLEIQAKLPLEQQA----ALKTGK 235
I +P+ G + +QV+ G +S+G T + I +++ LP A A K GK
Sbjct 198 -ITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGK 256
Query 236 TIQFNIQGETQSR---SARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQ 292
+ T S+ L + D + I+ A ++ +L FV ++
Sbjct 257 PLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVD 316
Query 293 DQIQGQIIPLDSIQNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIV--KGLQSSDQI 350
+ +IP ++Q + FVWV+ + +K++ ++ D+Q +V G+ + D++
Sbjct 317 TEQNAVVIPTAALQMGNEGHFVWVLNSE--NKVSKHLVTPGIQDSQKVVIRAGISAGDRV 374
>Q8Z5F8 Multidrug resistance protein MdtA [Salmonella typhi]
Length=413
Score = 66.6 bits (161), Expect = 4e-15
Identities = 66/298 (22%), Positives = 123/298 (41%), Gaps = 15/298 (5%)
Query 65 GTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQA 124
GT+ A N +++++V ++ G+ V +L +++ LAQA+ LA A
Sbjct 79 GTVTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPSQFKVALAQAQGQLAKDNA 138
Query 125 QAELAHNLMLRKKRLLDQGFISRVEYEQSQVDYKGQLETANAQKANLDIALKADQDGIIR 184
A + R ++L +SR E + Q T A +AN+ A I
Sbjct 139 TLANARRDLARYQQLAKTNLVSRQELDAQQALVNETQGTIKADEANVASAQLQLDWSRIT 198
Query 185 SPLTGVITKRQVEPGQTVSAGQT--LFEIVDPKQLEIQAKLPLEQQA----ALKTGKTIQ 238
+P++G + +QV+ G +S+ T + I +++ LP A A K GKT+
Sbjct 199 APVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLPESDIATVVQAQKAGKTLV 258
Query 239 FNIQGETQSRSAR---LSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQDQI 295
T S L + D + I+ A ++ +L FV ++ +
Sbjct 259 VEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQ 318
Query 296 QGQIIPLDSIQNLDHQPFVWVIRQQ---KIHKINIQVLEKRFADNQAIVKGLQSSDQI 350
++P ++Q + FVWV+ + ++ I + + R N I GL + D++
Sbjct 319 NAVVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNR---NVVISAGLSAGDRV 373
>C0Q1F4 Multidrug resistance protein MdtA [Salmonella paratyphi
C (strain RKS4594)]
Length=413
Score = 66.6 bits (161), Expect = 4e-15
Identities = 66/298 (22%), Positives = 123/298 (41%), Gaps = 15/298 (5%)
Query 65 GTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQA 124
GT+ A N +++++V ++ G+ V +L +++ LAQA+ LA A
Sbjct 79 GTVTAANTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPSQFKVALAQAQGQLAKDNA 138
Query 125 QAELAHNLMLRKKRLLDQGFISRVEYEQSQVDYKGQLETANAQKANLDIALKADQDGIIR 184
A + R ++L +SR E + Q T A +AN+ A I
Sbjct 139 TLANARRDLARYQQLAKTNLVSRQELDAQQALVNETQGTIKADEANVASAQLQLDWSRIT 198
Query 185 SPLTGVITKRQVEPGQTVSAGQT--LFEIVDPKQLEIQAKLPLEQQA----ALKTGKTIQ 238
+P++G + +QV+ G +S+ T + I +++ LP A A K GKT+
Sbjct 199 APVSGRVGLKQVDVGNQISSSDTAGIVVITQTHPIDLIFTLPESDIATVVQAQKAGKTLV 258
Query 239 FNIQGETQSRSAR---LSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQDQI 295
T S L + D + I+ A ++ +L FV ++ +
Sbjct 259 VEAWDRTNSHKLSEGVLLSLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQ 318
Query 296 QGQIIPLDSIQNLDHQPFVWVIRQQ---KIHKINIQVLEKRFADNQAIVKGLQSSDQI 350
++P ++Q + FVWV+ + ++ I + + R N I GL + D++
Sbjct 319 NAVVVPAAAVQMGNEGHFVWVLNDENNVSKKRVKIGIQDNR---NVVISAGLSAGDRV 373
>B1LNW7 Multidrug resistance protein MdtA [Escherichia coli (strain
SMS-3-5 / SECEC)]
Length=415
Score = 66.6 bits (161), Expect = 4e-15
Identities = 66/300 (22%), Positives = 130/300 (43%), Gaps = 19/300 (6%)
Query 65 GTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQA 124
GTI A N +++++V ++ G+ V +L ++ LAQA LA +A
Sbjct 80 GTITAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPSQFKVALAQALGQLAKDKA 139
Query 125 QAELAHNLMLRKKRLLDQGFISRVEYEQSQV---DYKGQLETANAQKANLDIALKADQDG 181
A + R ++L+ +SR E + Q + +G ++ A A+ + L +
Sbjct 140 TLANARRDLARYQQLVKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSR-- 197
Query 182 IIRSPLTGVITKRQVEPGQTVSAGQT--LFEIVDPKQLEIQAKLPLEQQA----ALKTGK 235
I +P+ G + +QV+ G +S+G T + I +++ LP A A K GK
Sbjct 198 -ITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGK 256
Query 236 TIQFNIQGETQSR---SARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQ 292
+ T S+ L + D + I+ A ++ +L FV ++
Sbjct 257 PLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVD 316
Query 293 DQIQGQIIPLDSIQNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIV--KGLQSSDQI 350
+ +IP ++Q + FVWV+ + +K++ ++ D+Q +V G+ + D++
Sbjct 317 TEQNAVVIPTAALQMGNEGHFVWVLNSE--NKVSKHLVTPGIQDSQRVVIRAGISAGDRV 374
>B7ME86 Multidrug resistance protein MdtA [Escherichia coli O45:K1
(strain S88 / ExPEC)]
Length=415
Score = 66.6 bits (161), Expect = 4e-15
Identities = 66/300 (22%), Positives = 130/300 (43%), Gaps = 19/300 (6%)
Query 65 GTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQA 124
GTI A N +++++V ++ G+ V +L ++ LAQA+ LA +A
Sbjct 80 GTITAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKA 139
Query 125 QAELAHNLMLRKKRLLDQGFISRVEYEQSQV---DYKGQLETANAQKANLDIALKADQDG 181
A + R ++L +SR E + Q + +G ++ A A+ + L +
Sbjct 140 TLANARRDLSRYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSR-- 197
Query 182 IIRSPLTGVITKRQVEPGQTVSAGQT--LFEIVDPKQLEIQAKLPLEQQA----ALKTGK 235
I +P+ G + +QV+ G +S+G T + I +++ LP A A K GK
Sbjct 198 -ITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGK 256
Query 236 TIQFNIQGETQSR---SARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQ 292
+ T S+ L + D + I+ A ++ +L FV ++
Sbjct 257 PLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVD 316
Query 293 DQIQGQIIPLDSIQNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIV--KGLQSSDQI 350
+ +IP ++Q + FVWV+ + +K++ ++ D+Q +V G+ + D++
Sbjct 317 TEQNAVVIPTAALQMGNEGHFVWVLNSE--NKVSKHLVTPGIQDSQKVVIRAGISAGDRV 374
>Q83KI5 Putative multidrug resistance protein MdtA [Shigella flexneri]
Length=350
Score = 66.2 bits (160), Expect = 4e-15
Identities = 65/300 (22%), Positives = 129/300 (43%), Gaps = 19/300 (6%)
Query 65 GTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQA 124
GTI A N +++++V ++ G+ V +L ++ LAQ + LA +A
Sbjct 15 GTITAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPSQFKVALAQTQGQLAKDKA 74
Query 125 QAELAHNLMLRKKRLLDQGFISRVEYEQSQV---DYKGQLETANAQKANLDIALKADQDG 181
A + R ++L +SR E + Q + +G ++ A A+ + L +
Sbjct 75 TLANARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSR-- 132
Query 182 IIRSPLTGVITKRQVEPGQTVSAGQT--LFEIVDPKQLEIQAKLPLEQQA----ALKTGK 235
I +P+ G + +QV+ G +S+G T + I +++ LP A A K GK
Sbjct 133 -ITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGK 191
Query 236 TIQFNIQGETQSR---SARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQ 292
+ T S+ L + D + I+ A ++ +L FV ++
Sbjct 192 PLMVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVD 251
Query 293 DQIQGQIIPLDSIQNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIV--KGLQSSDQI 350
+ +IP ++Q + FVWV+ + +K++ ++ D+Q +V G+ + D++
Sbjct 252 TEQNAVVIPTAALQMGNEGHFVWVLNSE--NKVSKHLVTPGIQDSQKVVIRAGISAGDRV 309
>P0AE06 Multidrug efflux pump subunit AcrA [Escherichia coli (strain
K12)]
Length=397
Score = 63.5 bits (153), Expect = 4e-14
Identities = 53/191 (28%), Positives = 84/191 (44%), Gaps = 6/191 (3%)
Query 16 VLSLSLMLVACSKPESDPPAQTSSQSIELIAQDLIAVRTGELQTKIPFTGTIRAVNQSSI 75
+LS SL L C D AQ Q + + ++ V+T LQ G A + +
Sbjct 15 MLSGSLALTGCD----DKQAQQGGQQMPAVG--VVTVKTEPLQITTELPGRTSAYRIAEV 68
Query 76 QAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQAQAELAHNLMLR 135
+ QV+ + N G + L +++ A A+ +LA AQA A +A + R
Sbjct 69 RPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQATYDSAKGDLAKAQAAANIAQLTVNR 128
Query 136 KKRLLDQGFISRVEYEQSQVDYKGQLETANAQKANLDIALKADQDGIIRSPLTGVITKRQ 195
++LL +IS+ EY+Q+ D + A KA ++ A + SP++G I K
Sbjct 129 YQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETARINLAYTKVTSPISGRIGKSN 188
Query 196 VEPGQTVSAGQ 206
V G V GQ
Sbjct 189 VTEGALVQNGQ 199
>P52599 Probable multidrug resistance protein EmrK [Escherichia
coli (strain K12)]
Length=387
Score = 63.2 bits (152), Expect = 5e-14
Identities = 61/252 (24%), Positives = 106/252 (42%), Gaps = 54/252 (21%)
Query 56 ELQTKIPFTGTIRAVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQA 115
EL+ I N I AQV+ + T VN V + +LV L+ D L +A
Sbjct 38 ELEDMISTDDAYVTGNADPISAQVSGSVTVVNHKDTNYVRQGDILVSLDKTDATIALNKA 97
Query 116 RANLASAQAQAELAHNLMLRKKRLLDQGFISRVEYEQSQVDYKGQL-------------- 161
+ NLA+ Q + L L+ K+ + +R++Y+QS DY ++
Sbjct 98 KNNLANIVRQT---NKLYLQDKQYSAEVASARIQYQQSLEDYNRRVPLAKQGVISKETLE 154
Query 162 ---ETANAQKANLDIALKADQDGI--------------------------------IRSP 186
+T + KA L+ A++A + I+SP
Sbjct 155 HTKDTLISSKAALNAAIQAYKANKALVMNTPLNRQPQVVEAADATKEAWLALKRTDIKSP 214
Query 187 LTGVITKRQVEPGQTVSAGQTLFEIVDPKQLEIQAKLPLEQQAALKTGKTIQF--NIQGE 244
+TG I +R V+ G+TVS GQ+L +V +Q+ + A Q ++ G+++ ++ GE
Sbjct 215 VTGYIAQRSVQVGETVSPGQSLMAVVPARQMWVNANFKETQLTDVRIGQSVNIISDLYGE 274
Query 245 TQSRSARLSRIS 256
R++ I+
Sbjct 275 NVVFHGRVTGIN 286
>Q9KJC3 Antibiotic efflux pump periplasmic linker protein ArpA
[Pseudomonas putida]
Length=371
Score = 59.7 bits (143), Expect = 6e-13
Identities = 77/357 (22%), Positives = 144/357 (40%), Gaps = 46/357 (13%)
Query 15 SVLSLSLMLVACSKPESDPPAQTSSQSIELIAQDLIAVRTGELQTKIPFTGTIRAVNQSS 74
S ++L+ +L C K E+ P AQ + I + T EL G A +
Sbjct 12 SAVALATLLSGCKKEEAAPAAQAPQVGVVTIQPQAFTL-TSELP------GRTSAYRVAE 64
Query 75 IQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQAQAELAHNLML 134
++ QV + G V + Q L +++ A LA A+ANL + ++ AE
Sbjct 65 VRPQVNGIILKRLFKEGSEVKEGQQLYQIDPAVYEATLANAKANLLATRSLAE------- 117
Query 135 RKKRLLDQGFISRVEYEQSQVDYKGQLETANAQKANLDIALKADQDGI----IRSPLTGV 190
R K+L+D+ +S+ EY+ ANA++ + +LK+ Q + + +P++G
Sbjct 118 RYKQLIDEQAVSKQEYDD-----------ANAKRLQAEASLKSAQIDLRYTKVLAPISGR 166
Query 191 ITKRQVEPGQTVSAGQT----LFEIVDPKQLEI--------QAKLPLEQQAALKTGK--- 235
I + G VS GQT + +DP +++ + + LE K G
Sbjct 167 IGRSSFTEGALVSNGQTDAMATIQQLDPIYVDVTQSTAELLKLRRDLESGQLQKAGNNAA 226
Query 236 TIQFNIQ-GETQSRSARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQDQ 294
++Q ++ G + RL D+ + + A + +L G FV +
Sbjct 227 SVQLVLEDGSLFKQEGRLEFSEVAVDETTGSVTLRALFPNPDHTLLPGMFVHARLKAGVN 286
Query 295 IQGQIIPLDSI-QNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIVKGLQSSDQI 350
+ P + ++L P V+ Q+ ++ + + I +GL D++
Sbjct 287 ANAILAPQQGVTRDLKGAPTALVVNQENKVELRQLKASRTLGSDWLIEEGLNPGDRL 343
>Q9WWZ9 Toluene efflux pump periplasmic linker protein TtgA [Pseudomonas
putida (strain DOT-T1E)]
Length=384
Score = 59.7 bits (143), Expect = 6e-13
Identities = 77/357 (22%), Positives = 144/357 (40%), Gaps = 46/357 (13%)
Query 15 SVLSLSLMLVACSKPESDPPAQTSSQSIELIAQDLIAVRTGELQTKIPFTGTIRAVNQSS 74
S ++L+ +L C K E+ P AQ + I + T EL G A +
Sbjct 12 SAVALATLLSGCKKEEAAPAAQAPQVGVVTIQPQAFTL-TSELP------GRTSAYRVAE 64
Query 75 IQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQAQAELAHNLML 134
++ QV + G V + Q L +++ A LA A+ANL + ++ AE
Sbjct 65 VRPQVNGIILKRLFKEGSEVKEGQQLYQIDPAVYEATLANAKANLLATRSLAE------- 117
Query 135 RKKRLLDQGFISRVEYEQSQVDYKGQLETANAQKANLDIALKADQDGI----IRSPLTGV 190
R K+L+D+ +S+ EY+ ANA++ + +LK+ Q + + +P++G
Sbjct 118 RYKQLIDEQAVSKQEYDD-----------ANAKRLQAEASLKSAQIDLRYTKVLAPISGR 166
Query 191 ITKRQVEPGQTVSAGQT----LFEIVDPKQLEI--------QAKLPLEQQAALKTGK--- 235
I + G VS GQT + +DP +++ + + LE K G
Sbjct 167 IGRSSFTEGALVSNGQTDAMATIQQLDPIYVDVTQSTAELLKLRRDLESGQLQKAGNNAA 226
Query 236 TIQFNIQ-GETQSRSARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQDQ 294
++Q ++ G + RL D+ + + A + +L G FV +
Sbjct 227 SVQLVLEDGSLFKQEGRLEFSEVAVDETTGSVTLRALFPNPDHTLLPGMFVHARLKAGVN 286
Query 295 IQGQIIPLDSI-QNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIVKGLQSSDQI 350
+ P + ++L P V+ Q+ ++ + + I +GL D++
Sbjct 287 ANAILAPQQGVTRDLKGAPTALVVNQENKVELRQLKASRTLGSDWLIEEGLNPGDRL 343
>Q88N30 Probable efflux pump periplasmic linker TtgA [Pseudomonas
putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB
11950 / KT2440)]
Length=384
Score = 59.3 bits (142), Expect = 8e-13
Identities = 77/357 (22%), Positives = 144/357 (40%), Gaps = 46/357 (13%)
Query 15 SVLSLSLMLVACSKPESDPPAQTSSQSIELIAQDLIAVRTGELQTKIPFTGTIRAVNQSS 74
S ++L+ +L C K E+ P AQ + I + T EL G A +
Sbjct 12 SAVALATLLSGCKKEEAAPAAQAPQVGVVTIQPQAFTL-TSELP------GRTSAYRVAE 64
Query 75 IQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQAQAELAHNLML 134
++ QV + G V + Q L +++ A LA A+ANL + ++ AE
Sbjct 65 VRPQVNGIILKRLFKEGSEVKEGQQLYQIDPAVYEATLANAKANLLATRSLAE------- 117
Query 135 RKKRLLDQGFISRVEYEQSQVDYKGQLETANAQKANLDIALKADQDGI----IRSPLTGV 190
R K+L+D+ +S+ EY+ ANA++ + +LK+ Q + + +P++G
Sbjct 118 RYKQLIDEQAVSKQEYDD-----------ANAKRLQAEASLKSAQIDLRYTKVLAPISGR 166
Query 191 ITKRQVEPGQTVSAGQT----LFEIVDPKQLEI--------QAKLPLEQQAALKTG---K 235
I + G VS GQT + +DP +++ + + LE K G
Sbjct 167 IGRSSFTEGALVSNGQTDAMATIQQLDPIYVDVTQSTAELLKLRRDLESGQLQKAGDNAA 226
Query 236 TIQFNIQ-GETQSRSARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQDQ 294
++Q ++ G + RL D+ + + A + +L G FV +
Sbjct 227 SVQLVLEDGSLFKQEGRLEFSEVAVDETTGSVTLRALFPNPDHTLLPGMFVHARLKAGVN 286
Query 295 IQGQIIPLDSI-QNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIVKGLQSSDQI 350
+ P + ++L P V+ Q+ ++ + + I +GL D++
Sbjct 287 ANAILAPQQGVTRDLKGAPTALVVNQENKVELRQLKASRTLGSDWLIEEGLNPGDRL 343
>P0C069 Multidrug/solvent efflux pump periplasmic linker protein
MepA [Pseudomonas putida]
Length=384
Score = 59.3 bits (142), Expect = 8e-13
Identities = 77/357 (22%), Positives = 144/357 (40%), Gaps = 46/357 (13%)
Query 15 SVLSLSLMLVACSKPESDPPAQTSSQSIELIAQDLIAVRTGELQTKIPFTGTIRAVNQSS 74
S ++L+ +L C K E+ P AQ + I + T EL G A +
Sbjct 12 SAVALATLLSGCKKEEAAPAAQAPQVGVVTIQPQAFTL-TSELP------GRTSAYRVAE 64
Query 75 IQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQAQAELAHNLML 134
++ QV + G V + Q L +++ A LA A+ANL + ++ AE
Sbjct 65 VRPQVNGIILKRLFKEGSEVKEGQQLYQIDPAVYEATLANAKANLLATRSLAE------- 117
Query 135 RKKRLLDQGFISRVEYEQSQVDYKGQLETANAQKANLDIALKADQDGI----IRSPLTGV 190
R K+L+D+ +S+ EY+ ANA++ + +LK+ Q + + +P++G
Sbjct 118 RYKQLIDEQAVSKQEYDD-----------ANAKRLQAEASLKSAQIDLRYTKVLAPISGR 166
Query 191 ITKRQVEPGQTVSAGQT----LFEIVDPKQLEI--------QAKLPLEQQAALKTG---K 235
I + G VS GQT + +DP +++ + + LE K G
Sbjct 167 IGRSSFTEGALVSNGQTDAMATIQQLDPIYVDVTQSTAELLKLRRDLESGQLQKAGDNAA 226
Query 236 TIQFNIQ-GETQSRSARLSRISPVADQASRQIEFFATPSDVIQSLSIGAFVEGFIINQDQ 294
++Q ++ G + RL D+ + + A + +L G FV +
Sbjct 227 SVQLVLEDGSLFKQEGRLEFSEVAVDETTGSVTLRALFPNPDHTLLPGMFVHARLKAGVN 286
Query 295 IQGQIIPLDSI-QNLDHQPFVWVIRQQKIHKINIQVLEKRFADNQAIVKGLQSSDQI 350
+ P + ++L P V+ Q+ ++ + + I +GL D++
Sbjct 287 ANAILAPQQGVTRDLKGAPTALVVNQENKVELRQLKASRTLGSDWLIEEGLNPGDRL 343
>P27303 Multidrug export protein EmrA [Escherichia coli (strain
K12)]
Length=390
Score = 59.3 bits (142), Expect = 8e-13
Identities = 57/227 (25%), Positives = 95/227 (42%), Gaps = 54/227 (24%)
Query 69 AVNQSSIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARLAQARANLASAQAQAEL 128
A NQ I +QV+ + T+V AD + V + VLV L+ D +A+ LAS+ Q
Sbjct 58 AGNQIQIMSQVSGSVTKVWADNTDFVKEGDVLVTLDPTDARQAFEKAKTALASSVRQ--- 114
Query 129 AHNLMLRKKRLLDQGFISRVEYEQSQVDYKGQLETANAQ-----------------KANL 171
H LM+ K+L + ++ ++Q DY ++ NA +A L
Sbjct 115 THQLMINSKQLQANIEVQKIALAKAQSDYNRRVPLGNANLIGREELQHARDAVTSAQAQL 174
Query 172 DIALK--------------ADQDGI------------------IRSPLTGVITKRQVEPG 199
D+A++ DQ + I SP+TG +++R V+PG
Sbjct 175 DVAIQQYNANQAMILGTKLEDQPAVQQAATEVRNAWLALERTRIISPMTGYVSRRAVQPG 234
Query 200 QTVSAGQTLFEIVDPKQLEIQAKLPLEQQAALKTGK--TIQFNIQGE 244
+S L +V + + A Q A ++ G+ TI +I G+
Sbjct 235 AQISPTTPLMAVVPATNMWVDANFKETQIANMRIGQPVTITTDIYGD 281
Lambda K H a alpha
0.317 0.130 0.344 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 2730348
Database: 78e50b12f50545ce919cb3e42220437a.SwissProt.fasta
Posted date: May 31, 2024 6:49 PM
Number of letters in database: 9,886
Number of sequences in database: 25
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
Loading
Data ...
