BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 59a86c05a07b06a16f68b0af1a360251.SwissProt.fasta
13 sequences; 3,768 total letters
Query= ACIAD0803
Length=237
Score E
Sequences producing significant alignments: (Bits) Value
Q5XW77 Chloronitrobenzene nitroreductase [Comamonas testosteroni] 146 5e-47
Q6DLR9 Nitrobenzene nitroreductase [Pseudomonas oleovorans] 141 3e-45
A0R6D0 Nitroreductase NfnB [Mycolicibacterium smegmatis (strain A... 87.8 2e-24
P34273 Iodotyrosine dehalogenase 1 homolog [Caenorhabditis elegans] 52.0 2e-11
A7S5D9 Iodotyrosine deiodinase [Nematostella vectensis] 50.8 4e-11
F4KU78 Iodotyrosine deiodinase [Haliscomenobacter hydrossis (stra... 47.4 5e-10
Q60049 NADH dehydrogenase [Thermus thermophilus (strain ATCC 2763... 45.4 2e-09
E7FDV5 Iodotyrosine deiodinase [Danio rerio] 45.1 4e-09
Q9KZK8 Coenzyme F420:L-glutamate ligase / Dehydro-coenzyme F420-0... 45.1 5e-09
Q8GED9 Albonoursin synthase [Streptomyces noursei] 41.2 6e-08
P9WP79 Coenzyme F420:L-glutamate ligase / Dehydro-coenzyme F420-0... 39.3 4e-07
Q7TWV3 Coenzyme F420:L-glutamate ligase / Dehydro-coenzyme F420-0... 39.3 4e-07
Q2RNG5 5,6-dimethylbenzimidazole synthase [Rhodospirillum rubrum ... 37.7 8e-07
>Q5XW77 Chloronitrobenzene nitroreductase [Comamonas testosteroni]
Length=227
Score = 146 bits (368), Expect = 5e-47
Identities = 80/233 (34%), Positives = 123/233 (53%), Gaps = 22/233 (9%)
Query 11 VDQAIMSRHSVRAFLSTPIEPQIIKDILAVASRAPSGTNTQPWKVYVVTGQTRDTMIRRV 70
+D I R + R FL P+ +++KDIL+VA PS +NTQPW+ YV+TG+ R+ +
Sbjct 7 IDDLIRDRRTKRGFLDQPVPIEMVKDILSVAKYTPSSSNTQPWRCYVLTGEARERVTTAA 66
Query 71 CEAQMALTNDPSHAEHYQETFAYYPEKWISPFIDRRRENGWGLYGLLNIQKGEKEKMAQQ 130
EA E + ++Y+PE P+ R + Q G+ E +
Sbjct 67 VEAYRGAP------EGLKPEYSYFPEPLHEPYATR--------FNSFRGQLGDAEGCCRS 112
Query 131 QL--------RNFQLFDAPVGLYFTVNKMMGIGSKMDISMMIQNVMIAAKARGLDTCPQA 182
+ R F+ FDAPVGL FT+++ + S + +QN+M+AAK RGLDTCPQ
Sbjct 113 DITGRRRYVERQFRFFDAPVGLIFTMDRRLEWASFICYGCFLQNIMLAAKGRGLDTCPQG 172
Query 183 AWNHFHPIVLDVLHAPEDEELVCTVALGYADPDHIVNTFITPRESVESFTQFL 235
W+ HP++ L+ P+D+ +V ++LG+AD VN R +E FT F+
Sbjct 173 LWSLQHPVLRTELNLPDDQMVVAGMSLGWADNSMAVNQMSMSRVELEEFTTFV 225
>Q6DLR9 Nitrobenzene nitroreductase [Pseudomonas oleovorans]
Length=227
Score = 141 bits (356), Expect = 3e-45
Identities = 76/225 (34%), Positives = 119/225 (53%), Gaps = 6/225 (3%)
Query 11 VDQAIMSRHSVRAFLSTPIEPQIIKDILAVASRAPSGTNTQPWKVYVVTGQTRDTMIRRV 70
+D I R + R FL P+ +++KDIL+ A APS +NTQPW+ YV+TG+ R+ +
Sbjct 7 IDDLIRDRRAKRGFLDQPVSIEMVKDILSAAKYAPSSSNTQPWRCYVITGEARERITTAA 66
Query 71 CEAQMALTNDPSHAEHYQETFAYYPEKWISPFIDRRRENGWGLYGLLNIQKGEKEKMAQQ 130
EA A E + ++P+ P+ R L L I + + +
Sbjct 67 VEAYRAAP------EGLPPEYPFFPQPLHEPYATRFNSFRGQLGDALGIPRSDITLRRRD 120
Query 131 QLRNFQLFDAPVGLYFTVNKMMGIGSKMDISMMIQNVMIAAKARGLDTCPQAAWNHFHPI 190
R F+ FDAPVGL FT+++ + S + +QN+M+AAK RGLDTC Q W+ HP+
Sbjct 121 VERQFRFFDAPVGLIFTMDRRLEWASFICYGCFLQNIMLAAKGRGLDTCTQVFWSMQHPV 180
Query 191 VLDVLHAPEDEELVCTVALGYADPDHIVNTFITPRESVESFTQFL 235
+ L+ P+D+ +V ++LG+AD N + +E FT F+
Sbjct 181 LRTELNLPDDQMVVAGMSLGWADNSLPENQMSISKMELEEFTTFV 225
>A0R6D0 Nitroreductase NfnB [Mycolicibacterium smegmatis (strain
ATCC 700084 / mc(2)155)]
Length=234
Score = 87.8 bits (216), Expect = 2e-24
Identities = 66/228 (29%), Positives = 106/228 (46%), Gaps = 13/228 (6%)
Query 9 QLVDQAIMSRHSVRAFLSTPIEPQIIKDILAVASRAPSGTNTQPWKVYVVTGQTRDTMIR 68
Q ++ I R +VRAF + + ++ + +A APS +NTQPW V VV+G RD
Sbjct 16 QAAERLIKGRRAVRAFRPDEVPEETMRAVFELAGHAPSNSNTQPWHVEVVSGAARD---- 71
Query 69 RVCEAQMALTNDPSHA-EHYQETFAYYPEKWISPFIDRRRENGWGLYGLLNIQKGEKEKM 127
R+ EA + +HA E F Y + +RR + G LY L I + + + +
Sbjct 72 RLAEALVT-----AHAEERVTVDFPYREGLFQGVLQERRADFGSRLYAALGIARDQTDLL 126
Query 128 AQQQLRNFQLFDAP-VGLYFTVNKMMGIGSKMDISMMIQNVMIAAKARGLDTCPQAAWNH 186
+ + + AP V + F N D+ + Q +M+A A G+ +CPQA +
Sbjct 127 QGYNTESLRFYGAPHVAMLFAPNNTEA-RIAGDMGIYAQTLMLAMTAHGIASCPQALLSF 185
Query 187 FHPIVLDVLHAPEDEELVCTVALGYADPDHIVNTFITPRESVESFTQF 234
+ V L E+ +L+ ++ GYAD VN PR + T+F
Sbjct 186 YADTVRAEL-GVENRKLLMGISFGYADDTAAVNGVRIPRAGLSETTRF 232
>P34273 Iodotyrosine dehalogenase 1 homolog [Caenorhabditis elegans]
Length=325
Score = 52.0 bits (123), Expect = 2e-11
Identities = 58/247 (23%), Positives = 100/247 (40%), Gaps = 50/247 (20%)
Query 1 MPMQSEQIQLVDQAIM-----SRHSVRAFLSTPIEPQIIKDILAVASRAPSGTNTQPWKV 55
MP+ ++ I L + I R S R F S + ++I+++L A +PS N QPW
Sbjct 113 MPVINDDITLRNSQIFYEEMKMRRSCRQFSSRDVPLKVIQNLLKTAGTSPSVGNLQPWTF 172
Query 56 YVVTGQTRDTMIRRVCEAQMALTNDPSHAEHYQETFAYYPEKWISPFIDRRRENGWGLYG 115
VV+ + TMIR++ EA ++ R++ W
Sbjct 173 CVVSSDSIKTMIRKILEADER-----------------------DNYVSRKKGASW---- 205
Query 116 LLNIQKGEKEKMAQQQLRNFQLFDAPVGLYFTVNKMMGIGSK---------MDISMMIQN 166
++++ + Q R + DAP L + SK + S+ +
Sbjct 206 VVDVSQ------LQDTWRRPYITDAPYLLIVCHEIFRDVHSKTERVFHYNQISTSIAVGI 259
Query 167 VMIAAKARGLDTCPQAAWNHFHPIVLDVLHAPEDEELVCTVALGYADPDHIVNTFITPRE 226
++ A + GL T + N P + +L PE+E ++ + LGYA D +V R+
Sbjct 260 LLAAIQNVGLSTVVTSPLN-AGPDISRILRRPENESILLLLPLGYASEDVLVPDL--KRK 316
Query 227 SVESFTQ 233
VE T+
Sbjct 317 PVEHITK 323
>A7S5D9 Iodotyrosine deiodinase [Nematostella vectensis]
Length=264
Score = 50.8 bits (120), Expect = 4e-11
Identities = 45/217 (21%), Positives = 90/217 (41%), Gaps = 27/217 (12%)
Query 13 QAIMSRHSVRAFLSTPIEPQIIKDILAVASRAPSGTNTQPWKVYVVTGQTRDTMIRRVCE 72
+++ R +VR S P+ ++I++I+ VA +PSG +T+PW V+ I+ V E
Sbjct 70 KSMKKRRTVRKISSEPVPLEVIENIVRVAGTSPSGAHTEPWTYVVIRDPDLKKQIKEVVE 129
Query 73 AQMALTNDPSHAEHYQETFAYYPEKWISPFIDRRRENGWGLYGLLNIQKGEKEKMAQQQL 132
+ L E + + + W P+I+ Y +L
Sbjct 130 EEEQLNYARRMGEKWVQDLSILKTTWSKPYIET------APYLIL--------------- 168
Query 133 RNFQLFDAPVGLYFTVNKMMGIGSKMDISMMIQNVMIAAKARGLDTCPQAAWNHFHPIVL 192
+F G+ +K + +++ + + ++ A + GL T N P +
Sbjct 169 ----IFKQVYGIKPDGDKKVHYYNEISVCISCGLLLAAIQNAGLVTVTSTPMN-AGPRLR 223
Query 193 DVLHAPEDEELVCTVALGYADPD-HIVNTFITPRESV 228
+L+ P++E+L+ + +GY D + N P E +
Sbjct 224 VLLNRPQNEKLIMLLPVGYPAKDAEVPNLTRKPLEEI 260
>F4KU78 Iodotyrosine deiodinase [Haliscomenobacter hydrossis (strain
ATCC 27775 / DSM 1100 / LMG 10767 / O)]
Length=222
Score = 47.4 bits (111), Expect = 5e-10
Identities = 28/100 (28%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Query 5 SEQIQLVDQAIMSRHSVRAFLSTPIEPQIIKDILAVASRAPSGTNTQPWKVYVVTGQTRD 64
+E Q +D R +VR F + I ++I++I+ AS APSG + QPW VV+
Sbjct 25 AEYYQFMDH----RRTVREFSNRAIPLEVIENIVMTASTAPSGAHKQPWTFVVVSDPQIK 80
Query 65 TMIRRVCEAQMALTNDPSHAEHYQETFAYYPEKWISPFID 104
IR+ E + + + + + E + W PF++
Sbjct 81 AKIRQAAEKEEFESYNGRMSNEWLEDLQPFGTDWHKPFLE 120
>Q60049 NADH dehydrogenase [Thermus thermophilus (strain ATCC
27634 / DSM 579 / HB8)]
Length=205
Score = 45.4 bits (106), Expect = 2e-09
Identities = 21/68 (31%), Positives = 33/68 (49%), Gaps = 0/68 (0%)
Query 14 AIMSRHSVRAFLSTPIEPQIIKDILAVASRAPSGTNTQPWKVYVVTGQTRDTMIRRVCEA 73
A + R S+R + P+ ++++IL A RAPS N QPW++ VV +R
Sbjct 13 AALKRRSIRRYRKDPVPEGLLREILEAALRAPSAWNLQPWRIVVVRDPATKRALREAAFG 72
Query 74 QMALTNDP 81
Q + P
Sbjct 73 QAHVEEAP 80
>E7FDV5 Iodotyrosine deiodinase [Danio rerio]
Length=295
Score = 45.1 bits (105), Expect = 4e-09
Identities = 21/87 (24%), Positives = 38/87 (44%), Gaps = 0/87 (0%)
Query 18 RHSVRAFLSTPIEPQIIKDILAVASRAPSGTNTQPWKVYVVTGQTRDTMIRRVCEAQMAL 77
R SVR P+ ++I +++ A APSG +T+PW VV+ IR + E + +
Sbjct 106 RRSVRFISPEPVPKEVIDNVIRTAGTAPSGAHTEPWTFVVVSDTDVKHRIREIIEEEEEI 165
Query 78 TNDPSHAEHYQETFAYYPEKWISPFID 104
+ + W+ ++D
Sbjct 166 NYKQRMGNKWVQDLKRLRTNWVKEYLD 192
>Q9KZK8 Coenzyme F420:L-glutamate ligase / Dehydro-coenzyme F420-0
reductase [Streptomyces coelicolor (strain ATCC BAA-471
/ A3(2) / M145)]
Length=443
Score = 45.1 bits (105), Expect = 5e-09
Identities = 22/69 (32%), Positives = 42/69 (61%), Gaps = 1/69 (1%)
Query 9 QLVDQAIMSRHSVRAFLSTPIEPQIIKDILAVASRAPSGTNTQPWK-VYVVTGQTRDTMI 67
+ V QA+ R +VRAF P++P ++ +A A AP+ +T PW+ V + +G++R ++
Sbjct 246 EAVRQAVTQRRTVRAFTDEPVDPGAVRRAVAAAVTAPAPHHTTPWRFVLLESGESRTRLL 305
Query 68 RRVCEAQMA 76
+ +A +A
Sbjct 306 DAMRDAWIA 314
Score = 18.1 bits (35), Expect = 2.4
Identities = 6/13 (46%), Positives = 8/13 (62%), Gaps = 0/13 (0%)
Query 111 WGLYGLLNIQKGE 123
W L GL +Q G+
Sbjct 19 WALPGLPEVQSGD 31
>Q8GED9 Albonoursin synthase [Streptomyces noursei]
Length=219
Score = 41.2 bits (95), Expect = 6e-08
Identities = 42/196 (21%), Positives = 79/196 (40%), Gaps = 52/196 (27%)
Query 15 IMSRHSVRAFLSTPIEPQIIKDILAVASRAPSGTNTQPWKVYVVTGQTRDTMIRRVCEAQ 74
+ +R +VR + P++ +I+ +L AP+ +N Q W VV R +RR+
Sbjct 44 LKTRTAVRNYAKEPVDDALIEQLLEAMLAAPTASNRQAWSFMVVR---RPAAVRRLRAFS 100
Query 75 MALTNDPSHAEHYQETFAYYPEKWISPFIDRRRENGWGLYGLLNIQKGEKEKMAQQQLRN 134
+ P+ ++ +DR ++ K++Q+
Sbjct 101 PGVLGTPAF--------------FVVACVDR------------SLTDNLSPKLSQK---- 130
Query 135 FQLFDAPVGLYFTVNKMMGIGSKMDISMMIQNVMIAAKARGLDTCPQAAWNHFHPIVLDV 194
+Y T SK+ ++M ++N+++AA A GL CP ++ IV +
Sbjct 131 ---------IYDT--------SKLCVAMAVENLLLAAHAAGLGGCPVGSFR--SDIVTSM 171
Query 195 LHAPEDEELVCTVALG 210
L PE E + V +G
Sbjct 172 LGIPEHIEPMLVVPIG 187
>P9WP79 Coenzyme F420:L-glutamate ligase / Dehydro-coenzyme F420-0
reductase [Mycobacterium tuberculosis (strain ATCC 25618
/ H37Rv)]
Length=448
Score = 39.3 bits (90), Expect = 4e-07
Identities = 50/203 (25%), Positives = 85/203 (42%), Gaps = 29/203 (14%)
Query 13 QAIMSRHSVRAFLSTPIEPQIIKDILAVASRAPSGTNTQPWK-VYVVTGQTRDTMIRRVC 71
QA + R SVR F + P+ +++ +A A AP+ +T+P + V++ T R ++ R+
Sbjct 255 QAQLLRRSVRRFSTDPVPGDLVEAAVAEALTAPAPHHTRPTRFVWLQTPAIRARLLDRMK 314
Query 72 EAQMA-LTNDPSHAEHYQETFAYYPEKWISPFIDRRRENGWGLYGLLNIQKGEKEKMAQQ 130
+ + LT+D A+ I+RR G LY +
Sbjct 315 DKWRSDLTSDGLPADA----------------IERRVARGQILYDAPEVVIPMLVPDGAH 358
Query 131 QLRNFQLFDAPVGLYFTVNKMMGIGSKMDISMMIQNVMIAAKARGLDTCPQAAWNHFHPI 190
+ DA + FTV + +Q +++A RGL +C + +
Sbjct 359 SYPDAARTDAEHTM-FTVA----------VGAAVQALLVALAVRGLGSCWIGSTIFAADL 407
Query 191 VLDVLHAPEDEELVCTVALGYAD 213
V D L P D E + +A+GYAD
Sbjct 408 VRDELDLPVDWEPLGAIAIGYAD 430
>Q7TWV3 Coenzyme F420:L-glutamate ligase / Dehydro-coenzyme F420-0
reductase [Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)]
Length=448
Score = 39.3 bits (90), Expect = 4e-07
Identities = 50/203 (25%), Positives = 85/203 (42%), Gaps = 29/203 (14%)
Query 13 QAIMSRHSVRAFLSTPIEPQIIKDILAVASRAPSGTNTQPWK-VYVVTGQTRDTMIRRVC 71
QA + R SVR F + P+ +++ +A A AP+ +T+P + V++ T R ++ R+
Sbjct 255 QAQLLRRSVRRFSTDPVPGDLVEAAVAEALTAPAPHHTRPTRFVWLQTPAIRARLLDRMK 314
Query 72 EAQMA-LTNDPSHAEHYQETFAYYPEKWISPFIDRRRENGWGLYGLLNIQKGEKEKMAQQ 130
+ + LT+D A+ I+RR G LY +
Sbjct 315 DKWRSDLTSDGLPADA----------------IERRVARGQILYDAPEVVIPMLVPDGAH 358
Query 131 QLRNFQLFDAPVGLYFTVNKMMGIGSKMDISMMIQNVMIAAKARGLDTCPQAAWNHFHPI 190
+ DA + FTV + +Q +++A RGL +C + +
Sbjct 359 SYPDAARTDAEHTM-FTVA----------VGAAVQALLVALAVRGLGSCWIGSTIFAADL 407
Query 191 VLDVLHAPEDEELVCTVALGYAD 213
V D L P D E + +A+GYAD
Sbjct 408 VRDELDLPVDWEPLGAIAIGYAD 430
>Q2RNG5 5,6-dimethylbenzimidazole synthase [Rhodospirillum rubrum
(strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB
8255 / S1)]
Length=211
Score = 37.7 bits (86), Expect = 8e-07
Identities = 22/58 (38%), Positives = 30/58 (52%), Gaps = 1/58 (2%)
Query 11 VDQAIMSRHSVRAFLSTPIEPQIIKDILAVASRAPSGTNTQPWK-VYVVTGQTRDTMI 67
+D R VR F PI+ + + +LA A APS N+QPW+ V V G R +I
Sbjct 15 LDALFQWRRDVRHFRKDPIDEETVARLLACADLAPSVGNSQPWRFVRVDDGARRGVII 72
Lambda K H a alpha
0.324 0.136 0.416 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 628290
Database: 59a86c05a07b06a16f68b0af1a360251.SwissProt.fasta
Posted date: May 21, 2024 12:04 AM
Number of letters in database: 3,768
Number of sequences in database: 13
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
