BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 02cb0e5cfbd3d25a4e2527a2a4ff91ba.SwissProt.fasta
17 sequences; 8,523 total letters
Query= ACIAD0927
Length=516
Score E
Sequences producing significant alignments: (Bits) Value
P0AEJ1 Multidrug export protein EmrB [Escherichia coli O157:H7] 440 8e-154
P0AEJ0 Multidrug export protein EmrB [Escherichia coli (strain K12)] 440 8e-154
P44927 Multidrug export protein EmrB [Haemophilus influenzae (str... 417 6e-145
Q9RQ29 Fatty acid resistance protein FarB [Neisseria gonorrhoeae] 404 1e-139
P52600 Probable multidrug resistance protein EmrY [Escherichia co... 399 2e-137
P0DPR7 Colistin resistance protein EmrB [Acinetobacter baumannii ... 215 1e-66
P96712 Multidrug resistance protein 3 [Bacillus subtilis (strain ... 209 2e-64
A1ACT2 Putative multidrug resistance protein MdtD [Escherichia co... 192 1e-58
Q1R9Z4 Putative multidrug resistance protein MdtD [Escherichia co... 192 2e-58
B7ME89 Putative multidrug resistance protein MdtD [Escherichia co... 192 2e-58
B7LV41 Putative multidrug resistance protein MdtD [Escherichia fe... 192 2e-58
B7MWZ0 Putative multidrug resistance protein MdtD [Escherichia co... 191 3e-58
P36554 Putative multidrug resistance protein MdtD [Escherichia co... 189 3e-57
P31474 Probable transport protein HsrA [Escherichia coli (strain ... 173 2e-51
P9WG91 Multidrug resistance protein Stp [Mycobacterium tuberculos... 171 3e-50
P9WJY5 Uncharacterized MFS-type transporter EfpA [Mycobacterium t... 166 3e-48
P46105 Probable actinorhodin transporter [Streptomyces coelicolor... 157 4e-45
>P0AEJ1 Multidrug export protein EmrB [Escherichia coli O157:H7]
Length=512
Score = 440 bits (1132), Expect = 8e-154
Identities = 218/495 (44%), Positives = 322/495 (65%), Gaps = 6/495 (1%)
Query 17 LSGGRLLLAAFVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICV 76
L G +L++ ++L+ FM VLD+TIANV++P I GNL S SQGTWV+TS+ VA AI +
Sbjct 7 LEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAISI 66
Query 77 PLTGWLASRFGTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTL 136
PLTGWLA R G V++F+ I F + S+ CG+S+SL ML+ R+ QG+ GPL+PLSQ+L
Sbjct 67 PLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSLNMLIFFRVIQGIVAGPLIPLSQSL 126
Query 137 LMRIFPQEKHSQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVLGTI 196
L+ +P K S A+ LW+MT ++ PI GPILGG ISDN W WIFFIN+P+G+ VL T+
Sbjct 127 LLNNYPPAKRSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVLMTL 186
Query 197 RLLSVAETETIRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVLGFI 256
+ L ET T R RIDA+GL LLV+ IG+LQ+MLD G E DWF+S I++ V+AV+
Sbjct 187 QTLRGRETRTERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVVAIC 246
Query 257 VFLIWEMTDRLPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVLIPQWLQMNLNYTATWA 316
++WE+TD P+V+L +F+ R FT+ L +S + +FG+IVL+PQ LQ YTATWA
Sbjct 247 FLIVWELTDDNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATWA 306
Query 317 GYLTATMGFGSLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAF-WTSDADFMTLAW 375
G +A +G +++SP++ + A K D R L +F ++ RA+ + DF AW
Sbjct 307 GLASAPVGIIPVILSPIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMDFGASAW 366
Query 376 PQILQGFAVPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIAVTIWDD--- 432
PQ +QGFAV FF+PL+ + LS + P+ LA+A+ L NF RT+AG+IG SI T+W +
Sbjct 367 PQFIQGFAVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSITTTMWTNRES 426
Query 433 --HAKVARSEMVSNLHSDDVYNTLIQSGFSSDTALGTISNLVDKESITMSSDHVFLIFSL 490
HA++ S N ++ +Y+ L G + A G I+ + + + +S++ +F + +
Sbjct 427 MHHAQLTESVNPFNPNAQAMYSQLEGLGMTQQQASGWIAQQITNQGLIISANEIFWMSAG 486
Query 491 VFVFAGLIIWLSPKP 505
+F+ ++W + P
Sbjct 487 IFLVLLGLVWFAKPP 501
>P0AEJ0 Multidrug export protein EmrB [Escherichia coli (strain
K12)]
Length=512
Score = 440 bits (1132), Expect = 8e-154
Identities = 218/495 (44%), Positives = 322/495 (65%), Gaps = 6/495 (1%)
Query 17 LSGGRLLLAAFVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICV 76
L G +L++ ++L+ FM VLD+TIANV++P I GNL S SQGTWV+TS+ VA AI +
Sbjct 7 LEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAISI 66
Query 77 PLTGWLASRFGTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTL 136
PLTGWLA R G V++F+ I F + S+ CG+S+SL ML+ R+ QG+ GPL+PLSQ+L
Sbjct 67 PLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSLNMLIFFRVIQGIVAGPLIPLSQSL 126
Query 137 LMRIFPQEKHSQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVLGTI 196
L+ +P K S A+ LW+MT ++ PI GPILGG ISDN W WIFFIN+P+G+ VL T+
Sbjct 127 LLNNYPPAKRSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVLMTL 186
Query 197 RLLSVAETETIRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVLGFI 256
+ L ET T R RIDA+GL LLV+ IG+LQ+MLD G E DWF+S I++ V+AV+
Sbjct 187 QTLRGRETRTERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVVAIC 246
Query 257 VFLIWEMTDRLPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVLIPQWLQMNLNYTATWA 316
++WE+TD P+V+L +F+ R FT+ L +S + +FG+IVL+PQ LQ YTATWA
Sbjct 247 FLIVWELTDDNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATWA 306
Query 317 GYLTATMGFGSLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAF-WTSDADFMTLAW 375
G +A +G +++SP++ + A K D R L +F ++ RA+ + DF AW
Sbjct 307 GLASAPVGIIPVILSPIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMDFGASAW 366
Query 376 PQILQGFAVPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIAVTIWDD--- 432
PQ +QGFAV FF+PL+ + LS + P+ LA+A+ L NF RT+AG+IG SI T+W +
Sbjct 367 PQFIQGFAVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSITTTMWTNRES 426
Query 433 --HAKVARSEMVSNLHSDDVYNTLIQSGFSSDTALGTISNLVDKESITMSSDHVFLIFSL 490
HA++ S N ++ +Y+ L G + A G I+ + + + +S++ +F + +
Sbjct 427 MHHAQLTESVNPFNPNAQAMYSQLEGLGMTQQQASGWIAQQITNQGLIISANEIFWMSAG 486
Query 491 VFVFAGLIIWLSPKP 505
+F+ ++W + P
Sbjct 487 IFLVLLGLVWFAKPP 501
>P44927 Multidrug export protein EmrB [Haemophilus influenzae
(strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=510
Score = 417 bits (1073), Expect = 6e-145
Identities = 206/498 (41%), Positives = 314/498 (63%), Gaps = 6/498 (1%)
Query 14 FAELSGGRLLLAAFVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEA 73
F + GG L+L ++L+ FM VLD+TIANV++P I G+L S SQGTWV+TS+ VA A
Sbjct 8 FPPIQGGALILLTLALSLATFMQVLDSTIANVAIPTIAGDLGASFSQGTWVITSFGVANA 67
Query 74 ICVPLTGWLASRFGTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLS 133
I +P+TGWLA RFG VR+F++ F V S+LCG++ SLE L++ R+ QG GP++PLS
Sbjct 68 ISIPITGWLAKRFGEVRLFLVSTFLFVVSSWLCGIADSLEALIIFRVIQGAVAGPVIPLS 127
Query 134 QTLLMRIFPQEKHSQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVL 193
Q+LL+ +P EK A+ W+MT V+ PI GPILGG ISDN+ W WIFFIN+P+G+ VL
Sbjct 128 QSLLLNNYPPEKRGMALAFWSMTIVVAPIFGPILGGWISDNIHWGWIFFINVPIGLSVVL 187
Query 194 GTIRLLSVAETETIRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVL 253
+ ++L E+E + ID +GL LLVL +G LQLMLD G E+DWFNS+ I++ AV+AV+
Sbjct 188 ISWKILGSRESEIVHQPIDKVGLVLLVLGVGCLQLMLDQGREQDWFNSNEIIILAVVAVV 247
Query 254 GFIVFLIWEMTDRLPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVLIPQWLQMNLNYTA 313
I +IWE+TD PVV++ +F R F+V L S F + GS+VLIP LQ +YTA
Sbjct 248 CLIALVIWELTDDNPVVDISLFHSRNFSVGCLCTSLAFLIYLGSVVLIPLLLQQVFHYTA 307
Query 314 TWAGYLTATMGFGSLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAF-WTSDADFMT 372
TWAG + +G +++SP++ + K D R L + ++ RA + F+
Sbjct 308 TWAGLAASPVGLFPILLSPIIGRFGYKIDMRILVTISFIVYAITFYWRAVTFEPSMTFVD 367
Query 373 LAWPQILQGFAVPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIAVTIWDD 432
+A PQ++QG AV FF+PL+ + LS + ++ASA+ L NFLRT+AG++G S+ +W +
Sbjct 368 VALPQLVQGLAVSCFFMPLTTITLSGLPAHKMASASSLFNFLRTLAGSVGTSLTTFMWYN 427
Query 433 HAKVARSEMVSNLH-----SDDVYNTLIQSGFSSDTALGTISNLVDKESITMSSDHVFLI 487
V +++ +++ S Y+ + Q G S ++ + + + ++ +F +
Sbjct 428 REAVHHTQLTEHINPYNPISQSFYHQMNQFGLSDTQTSAYLAQQITSQGFIIGANEIFWL 487
Query 488 FSLVFVFAGLIIWLSPKP 505
++ F+ ++IW + P
Sbjct 488 SAMGFLGLLIVIWFAKPP 505
>Q9RQ29 Fatty acid resistance protein FarB [Neisseria gonorrhoeae]
Length=507
Score = 404 bits (1037), Expect = 1e-139
Identities = 205/497 (41%), Positives = 300/497 (60%), Gaps = 5/497 (1%)
Query 14 FAELSGGRLLLAAFVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEA 73
+ L G L + L+ FM VLDTTIANV+VP I GNL + +QGTWV+TS++VA A
Sbjct 3 YPPLKGAALAWVTLSLGLAVFMEVLDTTIANVAVPVIAGNLGAATTQGTWVITSFSVANA 62
Query 74 ICVPLTGWLASRFGTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLS 133
+ VPLTG+LA R G V++F GF + S+LCG++ +L+ LV+ RI QG GPL+PLS
Sbjct 63 VSVPLTGFLAKRIGEVKLFTAAAAGFVIASWLCGIAPNLQSLVVFRILQGFIAGPLIPLS 122
Query 134 QTLLMRIFPQEKHSQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVL 193
Q+LLM +P K A+ LWAMT V+ P+LGPILGG IS N W WIFFINIP+GII
Sbjct 123 QSLLMASYPPAKRMLALALWAMTVVVAPVLGPILGGWISGNWHWGWIFFINIPIGIISAW 182
Query 194 GTIRLLSVAETETIRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVL 253
T + L ET T+R D +GL L+++ IGALQ+MLD G E DWF S I+ + A++
Sbjct 183 ITWKHLKHRETATVRTPTDYVGLTLMMVGIGALQMMLDRGKELDWFASGEIITLGITALV 242
Query 254 GFIVFLIWEMTDRLPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVLIPQWLQMNLNYTA 313
F++WE+ ++ P+V+L +F+ R FTV +A S GF + G++ L+P LQ NL YT+
Sbjct 243 CLSYFIVWELGEKYPIVDLSLFKDRNFTVGAIATSLGFMVYMGTLTLLPLVLQTNLGYTS 302
Query 314 TWAGYLTATMGFGSLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAFWTSDADFMTL 373
WAG A +G + +SP++ + K D R L + L R + +D D +
Sbjct 303 AWAGLAAAPVGILPVFLSPLIGRFGNKIDMRLLVTASFLTFAFTFYWRTDFYADMDIGNV 362
Query 374 AWPQILQGFAVPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIAVTIWDDH 433
WPQ QG V FF+PL+ + LS ++ ++A+A L NFLR + G +G S+ T+W+
Sbjct 363 IWPQFWQGVGVAMFFLPLTTITLSHMKGGQIAAAGSLSNFLRVLMGGVGVSVVSTLWERR 422
Query 434 AKVARSEMVSNL--HSDDVYNT---LIQSGFSSDTALGTISNLVDKESITMSSDHVFLIF 488
+ + ++ +S ++ T L Q G S LG I+N + ++ + S+ +FL
Sbjct 423 EALHHTRFAEHITPYSATLHETAAHLSQQGISDGQTLGIINNTITQQGFIIGSNEIFLAG 482
Query 489 SLVFVFAGLIIWLSPKP 505
S++F+ I+WL+ P
Sbjct 483 SILFIVLIPIVWLAKPP 499
>P52600 Probable multidrug resistance protein EmrY [Escherichia
coli (strain K12)]
Length=512
Score = 399 bits (1024), Expect = 2e-137
Identities = 196/505 (39%), Positives = 318/505 (63%), Gaps = 12/505 (2%)
Query 10 TKTPFAELSGGRLLLAAFVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYA 69
TK+ A L+GG L ++L+ FM +LD+TI+NV++P I+G L S +GTWV+TS+
Sbjct 4 TKSTPAPLTGGTLWCVTIALSLATFMQMLDSTISNVAIPTISGFLGASTDEGTWVITSFG 63
Query 70 VAEAICVPLTGWLASRFGTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPL 129
VA AI +P+TG LA R G +R+F++ + F++ S +C LST+L++L+ R+ QGL GPL
Sbjct 64 VANAIAIPVTGRLAQRIGELRLFLLSVTFFSLSSLMCSLSTNLDVLIFFRVVQGLMAGPL 123
Query 130 MPLSQTLLMRIFPQEKHSQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGI 189
+PLSQ+LL+R +P EK + A+ LW+MT ++ PI GPILGG I DN SW WIF IN+P+GI
Sbjct 124 IPLSQSLLLRNYPPEKRTFALALWSMTVIIAPICGPILGGYICDNFSWGWIFLINVPMGI 183
Query 190 ICVLGTIRLLSVAETETIRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAV 249
I + + LL ETET V+++ GL LLVL +G LQ+MLD G + DWFNSS I++ V
Sbjct 184 IVLTLCLTLLKGRETETSPVKMNLPGLTLLVLGVGGLQIMLDKGRDLDWFNSSTIIILTV 243
Query 250 IAVLGFIVFLIWEMTDRLPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVLIPQWLQMNL 309
++V+ I +IWE T P+++L +F+ R FT+ +++++ + + G+IVL+PQ LQ +
Sbjct 244 VSVISLISLVIWESTSENPILDLSLFKSRNFTIGIVSITCAYLFYSGAIVLMPQLLQETM 303
Query 310 NYTATWAGYLTATMGFGSLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAF-WTSDA 368
Y A WAG A +G L++SP++ + K D R L +F L+ R+ +
Sbjct 304 GYNAIWAGLAYAPIGIMPLLISPLIGRYGNKIDMRLLVTFSFLMYAVCYYWRSVTFMPTI 363
Query 369 DFMTLAWPQILQGFAVPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIAVT 428
DF + PQ QGFAV FF+PL+ ++ S + + A+A+ + NF RT++G++G S+ +T
Sbjct 364 DFTGIILPQFFQGFAVACFFLPLTTISFSGLPDNKFANASSMSNFFRTLSGSVGTSLTMT 423
Query 429 IWDDHAKVARSEMVSNLHSDDVYNTLIQSGF--------SSDTALGTISNLVDKESITMS 480
+W + S++ + + D +N + S S L I+N + ++S+++S
Sbjct 424 LWGRRESLHHSQLTATI---DQFNPVFNSSSQIMDKYYGSLSGVLNEINNEITQQSLSIS 480
Query 481 SDHVFLIFSLVFVFAGLIIWLSPKP 505
++ +F + ++ F+ +++W + P
Sbjct 481 ANEIFRMAAIAFILLTVLVWFAKPP 505
>P0DPR7 Colistin resistance protein EmrB [Acinetobacter baumannii
(strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 /
5377)]
Length=512
Score = 215 bits (547), Expect = 1e-66
Identities = 122/395 (31%), Positives = 212/395 (54%), Gaps = 3/395 (1%)
Query 33 NFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWLASRFGTVRVF 92
NFM +LD I S+ + ++ S + TWV T Y +AE I +P++ ++ T +
Sbjct 27 NFMAILDIQIVASSLNEVQAGMSASRYEVTWVQTVYLIAEIIAIPMSSIVSRVLSTRVYY 86
Query 93 VMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTLLMRIFPQEKHSQAMGL 152
M IGFTV S LC LS +LE L++ R QG GG ++P S T L +FP+ K S + +
Sbjct 87 TMCAIGFTVSSLLCALSWNLESLLVFRGIQGFMGGGMIPTSMTALYLLFPEPKRSLPLVM 146
Query 153 WAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGII--CVLGTIRLLSVAETETIRVR 210
+ M + LGP +GP +GG +++N SWHW+F INI GII V+ + + A I+
Sbjct 147 FGMISTLGPAIGPTIGGWLTNNFSWHWMFLINIIPGIIIATVIYSGPNIDRANYSLIK-S 205
Query 211 IDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVLGFIVFLIWEMTDRLPVV 270
+D L + +++G L+ LD G DW + + + ++ V+G ++F T P++
Sbjct 206 MDWFSLVGMAMFLGGLEYFLDEGARHDWLADTGVRIAFMVCVVGGMIFFSRSFTQPKPLL 265
Query 271 NLWVFRHRGFTVSVLALSFGFGAFFGSIVLIPQWLQMNLNYTATWAGYLTATMGFGSLMM 330
+L VF+++ FT+S + A +G +IP +L ++ G++ G
Sbjct 266 DLSVFKNKNFTLSAITTFVIGMALYGLGYMIPVFLGQVREMNSSQIGHVMMVTGIVMFCF 325
Query 331 SPVVAKLAAKYDPRALASFGLLLLGGVTLMRAFWTSDADFMTLAWPQILQGFAVPFFFIP 390
+P +A L +D R G++L G + + + +D+ + WPQI +G + I
Sbjct 326 APFLAWLIPNFDTRKTVFVGMILAGFGVWLNSHLSIHSDYDFMFWPQIYRGIGLMICLIV 385
Query 391 LSNLALSSVQPQELASAAGLMNFLRTMAGAIGASI 425
+S+LA+S++ ++A A+G+ N +R + GA+G ++
Sbjct 386 VSHLAMSTLPLSKVADASGIYNLMRNIGGAVGLAL 420
Score = 21.2 bits (43), Expect = 1.5
Identities = 9/22 (41%), Positives = 13/22 (59%), Gaps = 1/22 (5%)
Query 483 HVFLIFSLV-FVFAGLIIWLSP 503
HV ++ +V F FA + WL P
Sbjct 313 HVMMVTGIVMFCFAPFLAWLIP 334
Score = 19.2 bits (38), Expect = 5.9
Identities = 21/91 (23%), Positives = 42/91 (46%), Gaps = 6/91 (7%)
Query 156 TTVLGPIL---GPILGGLISDNLSWHWIFFINI--PVGIICVLGTIRLLSVAETETIRVR 210
T +G IL G L +S + + ++F+ I +G++ L + L+++ +V
Sbjct 341 TVFVGMILAGFGVWLNSHLSIHSDYDFMFWPQIYRGIGLMICLIVVSHLAMSTLPLSKVA 400
Query 211 IDAIGLFLLVLWIGALQLMLDLGHERDWFNS 241
DA G++ L+ IG + + DW +
Sbjct 401 -DASGIYNLMRNIGGAVGLALINSSLDWLTA 430
>P96712 Multidrug resistance protein 3 [Bacillus subtilis (strain
168)]
Length=512
Score = 209 bits (531), Expect = 2e-64
Identities = 147/489 (30%), Positives = 246/489 (50%), Gaps = 17/489 (3%)
Query 29 IALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWLASRFGT 88
+ L M +D TI ++ +I +L S + WV SY VA +P+ G L+ +G
Sbjct 18 LLLGILMSAMDNTIVATAMGNIVADLG-SFDKFAWVTASYMVAVMAGMPIYGKLSDMYGR 76
Query 89 VRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTLLMRIFPQEKHSQ 148
R F+ GLI F + S LCG++ ++ L++ R QG+ GG L+P++ T++ +FP EK +
Sbjct 77 KRFFLFGLIFFLIGSALCGIAQTMNQLIIFRAIQGIGGGALLPIAFTIIFDLFPPEKRGK 136
Query 149 AMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVLGTIRLLSVAETETIR 208
G++ L +LGP+LG +I+D++SWHW+F+IN+P+G + + IR E +
Sbjct 137 MSGMFGAVFGLSSVLGPLLGAIITDSISWHWVFYINVPIGALSLFFIIRYYK-ESLEHRK 195
Query 209 VRIDAIGLFLLVLWIGALQLMLDLGHER-DWFNSSIIVLFAVIAVLGFIVFLIWEMTDRL 267
+ID G LV+ I L L+LG + DW + II LF V AV FI F I E
Sbjct 196 QKIDWGGAITLVVSIVCLMFALELGGKTYDWNSIQIIGLFIVFAVF-FIAFFIVERKAEE 254
Query 268 PVVNLWVFRHRGF-TVSVLALSFGFGAFFGSIVLIPQWLQMNLNYTATWAGYLTATMGFG 326
P+++ W+F++R F T +LA +G G F V IP ++Q +AT AG++ M G
Sbjct 255 PIISFWMFKNRLFATAQILAFLYG-GTFIILAVFIPIFVQAVYGSSATSAGFILTPMMIG 313
Query 327 SLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAFWTSDADFMTLAWPQILQGFAVPF 386
S++ S + K R L ++ L+ + T D + L ++ GF V F
Sbjct 314 SVIGSMIGGIFQTKASFRNLMLISVIAFFIGMLLLSNMTPDTARVWLTVFMMISGFGVGF 373
Query 387 FFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIAVT----IWDDHAKVARSEMV 442
F L +++ ++P+ +A +FLR+ +G +I T ++ + A S M
Sbjct 374 NFSLLPAASMNDLEPRFRGTANSTNSFLRSFGMTLGVTIFGTVQTNVFTNKLNDAFSGMK 433
Query 443 SNLHSDDVYN-----TLIQSGFSSDTALGTISNLVDKESITMSSDHVFLIFSLVFVFAGL 497
+ S N + Q+G S ++ ++D +++ S +VFL+ + V A +
Sbjct 434 GSAGSGAAQNIGDPQEIFQAGTRSQIPDAILNRIID--AMSSSITYVFLLALIPIVLAAV 491
Query 498 IIWLSPKPK 506
I K +
Sbjct 492 TILFMGKAR 500
>A1ACT2 Putative multidrug resistance protein MdtD [Escherichia
coli O1:K1 / APEC]
Length=471
Score = 192 bits (489), Expect = 1e-58
Identities = 124/403 (31%), Positives = 205/403 (51%), Gaps = 9/403 (2%)
Query 27 FVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWLASRF 86
+++A FM LDTTI N ++P + +L S V+ SY + A+ +P +GWLA +
Sbjct 13 WIVAFGFFMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKV 72
Query 87 GTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTLLMRIFPQEKH 146
G +F ++ FT+ S C LS +L L+L R QG+ G ++P+ + +M+I P+E++
Sbjct 73 GVRNIFFTAIVLFTLGSLFCALSGTLNELLLARALQGVGGAMMVPVGRLTVMKIVPREQY 132
Query 147 SQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVLGTIRLLSVAETET 206
AM + +GP+LGP LGGL+ + SWHWIF INIPVGII + T+ L+ +T
Sbjct 133 MAAMTFVTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLMLMPNYTMQT 192
Query 207 IRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVLGFIVFLIWEMTDR 266
R D G LL + + L L LD G + F+ I + V+ +++L+ +
Sbjct 193 --RRFDLSGFLLLAVGMAVLTLALD-GSKGTGFSPLAIAGLVAVGVVALVLYLLHAQNNN 249
Query 267 LPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVL---IPQWLQMNLNYTATWAGYLTATM 323
+ +L +FR R F+ L L+ F GS +L P +LQ+ L ++ AG + M
Sbjct 250 RALFSLKLFRTRNFS---LGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPM 306
Query 324 GFGSLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAFWTSDADFMTLAWPQILQGFA 383
GS+ M +V ++ ++ R + L L VTL+ + L + LQG
Sbjct 307 VLGSMGMKRIVVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLFLQGMV 366
Query 384 VPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIA 426
F ++ L L + +S L++ + ++ +IG +IA
Sbjct 367 NSTRFSSMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIA 409
>Q1R9Z4 Putative multidrug resistance protein MdtD [Escherichia
coli (strain UTI89 / UPEC)]
Length=471
Score = 192 bits (487), Expect = 2e-58
Identities = 124/403 (31%), Positives = 205/403 (51%), Gaps = 9/403 (2%)
Query 27 FVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWLASRF 86
+++A FM LDTTI N ++P + +L S V+ SY + A+ +P +GWLA +
Sbjct 13 WIVAFGFFMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKV 72
Query 87 GTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTLLMRIFPQEKH 146
G +F ++ FT+ S C LS +L L+L R QG+ G ++P+ + +M+I P+E++
Sbjct 73 GVRNIFFTAIVLFTLGSLFCALSGTLNELLLARALQGVGGAMMVPVGRLTVMKIVPREQY 132
Query 147 SQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVLGTIRLLSVAETET 206
AM + +GP+LGP LGGL+ + SWHWIF INIPVGII + T+ L+ +T
Sbjct 133 MAAMTFVTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLMLMPNYTMQT 192
Query 207 IRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVLGFIVFLIWEMTDR 266
R D G LL + + L L LD G + F+ I + V+ +++L+ +
Sbjct 193 --RRFDLSGFLLLAVGMAVLTLALD-GSKGTGFSPLAIAGLVAVGVVALVLYLLHAQNNN 249
Query 267 LPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVL---IPQWLQMNLNYTATWAGYLTATM 323
+ +L +FR R F+ L L+ F GS +L P +LQ+ L ++ AG + M
Sbjct 250 RALFSLKLFRTRTFS---LGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPM 306
Query 324 GFGSLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAFWTSDADFMTLAWPQILQGFA 383
GS+ M +V ++ ++ R + L L VTL+ + L + LQG
Sbjct 307 VLGSMGMKRIVVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLFLQGMV 366
Query 384 VPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIA 426
F ++ L L + +S L++ + ++ +IG +IA
Sbjct 367 NSTRFSSMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIA 409
>B7ME89 Putative multidrug resistance protein MdtD [Escherichia
coli O45:K1 (strain S88 / ExPEC)]
Length=471
Score = 192 bits (487), Expect = 2e-58
Identities = 124/403 (31%), Positives = 205/403 (51%), Gaps = 9/403 (2%)
Query 27 FVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWLASRF 86
+++A FM LDTTI N ++P + +L S V+ SY + A+ +P +GWLA +
Sbjct 13 WIVAFGFFMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKV 72
Query 87 GTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTLLMRIFPQEKH 146
G +F ++ FT+ S C LS +L L+L R QG+ G ++P+ + +M+I P+E++
Sbjct 73 GVRNIFFTAIVLFTLGSLFCALSGTLNELLLARALQGVGGAMMVPVGRLTVMKIVPREQY 132
Query 147 SQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVLGTIRLLSVAETET 206
AM + +GP+LGP LGGL+ + SWHWIF INIPVGII + T+ L+ +T
Sbjct 133 MAAMTFVTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLMLMPNYTMQT 192
Query 207 IRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVLGFIVFLIWEMTDR 266
R D G LL + + L L LD G + F+ I + V+ +++L+ +
Sbjct 193 --RRFDLSGFLLLAVGMAVLTLALD-GSKGTGFSPLAIAGLVAVGVVALVLYLLHAQNNN 249
Query 267 LPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVL---IPQWLQMNLNYTATWAGYLTATM 323
+ +L +FR R F+ L L+ F GS +L P +LQ+ L ++ AG + M
Sbjct 250 RALFSLKLFRTRTFS---LGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPM 306
Query 324 GFGSLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAFWTSDADFMTLAWPQILQGFA 383
GS+ M +V ++ ++ R + L L VTL+ + L + LQG
Sbjct 307 VLGSMGMKRIVVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLFLQGMV 366
Query 384 VPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIA 426
F ++ L L + +S L++ + ++ +IG +IA
Sbjct 367 NSTRFSSMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIA 409
>B7LV41 Putative multidrug resistance protein MdtD [Escherichia
fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM
14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 /
CDC 0568-73)]
Length=471
Score = 192 bits (487), Expect = 2e-58
Identities = 125/403 (31%), Positives = 205/403 (51%), Gaps = 9/403 (2%)
Query 27 FVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWLASRF 86
+++A FM LDTTI N ++P + +L S V+ SY + A+ +P +GWLA +
Sbjct 13 WIVAFGFFMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKV 72
Query 87 GTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTLLMRIFPQEKH 146
G +F ++ FT+ S C LS +L L+L R QG+ G ++P+ + +M+I P+E++
Sbjct 73 GVRNIFFTAIVLFTLGSLFCALSATLNELLLARALQGVGGAMMVPVGRLTVMKIVPREQY 132
Query 147 SQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVLGTIRLLSVAETET 206
AM + +GP+LGP LGGL+ + SWHWIF INIPVGII + T+ L+ +T
Sbjct 133 MAAMTFVTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLMLMPNYTMQT 192
Query 207 IRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVLGFIVFLIWEMTDR 266
R D G LL + + L L LD G + + I A I V+ +++L+ +
Sbjct 193 --RRFDLSGFLLLAVGMAVLTLALD-GSKGTGLSPLAIAGLAAIGVVALVLYLLHARNNN 249
Query 267 LPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVL---IPQWLQMNLNYTATWAGYLTATM 323
+ +L +FR R F+ L L+ F GS +L P +LQ+ L ++ AG + M
Sbjct 250 RALFSLKLFRTRTFS---LGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPM 306
Query 324 GFGSLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAFWTSDADFMTLAWPQILQGFA 383
GS+ M +V ++ ++ R + L L VTL+ + L + LQG
Sbjct 307 VLGSMGMKRIVVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLFLQGMV 366
Query 384 VPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIA 426
F ++ L L + +S L++ + ++ +IG +IA
Sbjct 367 NSTRFSSMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIA 409
Score = 18.9 bits (37), Expect = 7.7
Identities = 15/65 (23%), Positives = 31/65 (48%), Gaps = 2/65 (3%)
Query 40 TTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWLASRFGTVRVFVMGLIGF 99
+++ +++ + NLA S + ++ +++ I V + G L FG+ V V
Sbjct 372 SSMNTLTLKDLPDNLASSGNSLLSMIMQLSMS--IGVTIAGLLLGLFGSQHVSVDSSTTQ 429
Query 100 TVFSF 104
TVF +
Sbjct 430 TVFMY 434
>B7MWZ0 Putative multidrug resistance protein MdtD [Escherichia
coli O81 (strain ED1a)]
Length=471
Score = 191 bits (486), Expect = 3e-58
Identities = 124/403 (31%), Positives = 205/403 (51%), Gaps = 9/403 (2%)
Query 27 FVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWLASRF 86
+++A FM LDTTI N ++P + +L S V+ SY + A+ +P +GWLA +
Sbjct 13 WIVAFGFFMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKV 72
Query 87 GTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTLLMRIFPQEKH 146
G +F ++ FT+ S C LS +L L+L R QG+ G ++P+ + +M+I P+E++
Sbjct 73 GVRNIFFTAIVLFTLGSLFCALSGTLNELLLARALQGVGGAMMVPVGRLTVMKIVPREQY 132
Query 147 SQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVLGTIRLLSVAETET 206
AM + +GP+LGP LGGL+ + SWHWIF INIPVGII + T+ L+ +T
Sbjct 133 MAAMTFVTLPGQIGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLMLMPNYTMQT 192
Query 207 IRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVLGFIVFLIWEMTDR 266
R D G LL + + L L LD G + F+ I + V+ +++L+ +
Sbjct 193 --RRFDLSGFLLLAVGMAVLTLALD-GSKGTGFSPLAIAGLVAVGVVALVLYLLHAQNNN 249
Query 267 LPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVL---IPQWLQMNLNYTATWAGYLTATM 323
+ +L +FR R F+ L L+ F GS +L P +LQ+ L ++ AG + M
Sbjct 250 RALFSLKLFRTRTFS---LGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPM 306
Query 324 GFGSLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAFWTSDADFMTLAWPQILQGFA 383
GS+ M +V ++ ++ R + L L VTL+ + L + LQG
Sbjct 307 VLGSMGMKRIVVQVVNRFGYRWVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLFLQGMV 366
Query 384 VPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIA 426
F ++ L L + +S L++ + ++ +IG +IA
Sbjct 367 NSTRFSSMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIA 409
>P36554 Putative multidrug resistance protein MdtD [Escherichia
coli (strain K12)]
Length=471
Score = 189 bits (479), Expect = 3e-57
Identities = 123/403 (31%), Positives = 204/403 (51%), Gaps = 9/403 (2%)
Query 27 FVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWLASRF 86
+++A FM LDTTI N ++P + +L S V+ SY + A+ +P +GWLA +
Sbjct 13 WIVAFGFFMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKV 72
Query 87 GTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTLLMRIFPQEKH 146
G +F ++ FT+ S C LS +L L+L R QG+ G ++P+ + +M+I P+E++
Sbjct 73 GVRNIFFTAIVLFTLGSLFCALSGTLNELLLARALQGVGGAMMVPVGRLTVMKIVPREQY 132
Query 147 SQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVLGTIRLLSVAETET 206
AM + +GP+LGP LGGL+ + SWHWIF INIPVGII + T+ L+ +T
Sbjct 133 MAAMTFVTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLLLMPNYTMQT 192
Query 207 IRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVLGFIVFLIWEMTDR 266
R D G LL + + L L LD G + + I + V+ +++L+ +
Sbjct 193 --RRFDLSGFLLLAVGMAVLTLALD-GSKGTGLSPLTIAGLVAVGVVALVLYLLHARNNN 249
Query 267 LPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVL---IPQWLQMNLNYTATWAGYLTATM 323
+ +L +FR R F+ L L+ F GS +L P +LQ+ L ++ AG + M
Sbjct 250 RALFSLKLFRTRTFS---LGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPM 306
Query 324 GFGSLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAFWTSDADFMTLAWPQILQGFA 383
GS+ M +V ++ ++ R + L L VTL+ + L + LQG
Sbjct 307 VLGSMGMKRIVVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLFLQGMV 366
Query 384 VPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIA 426
F ++ L L + +S L++ + ++ +IG +IA
Sbjct 367 NSTRFSSMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIA 409
>P31474 Probable transport protein HsrA [Escherichia coli (strain
K12)]
Length=475
Score = 173 bits (439), Expect = 2e-51
Identities = 113/424 (27%), Positives = 211/424 (50%), Gaps = 11/424 (3%)
Query 27 FVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWLASRF 86
++ A++ FM LD TI N ++P I +L S + SY + A+ +P++GWLA RF
Sbjct 14 WIAAMAFFMQALDATILNTALPAIAHSLNRSPLAMQSAIISYTLTVAMLIPVSGWLADRF 73
Query 87 GTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTLLMRIFPQEKH 146
GT R+F + + FT+ S C LS SL LV+ R+ QG+ G +MP+++ L+R +P+ +
Sbjct 74 GTRRIFTLAVSLFTLGSLACALSNSLPQLVVFRVIQGIGGAMMMPVARLALLRAYPRNEL 133
Query 147 SQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVLGTIRLLSVAETET 206
+ AM ++GPILGP+LGG++ +WHWIF INIP+GI +L + + T
Sbjct 134 LPVLNFVAMPGLVGPILGPVLGGVLVTWATWHWIFLINIPIGIAGLLYARK--HMPNFTT 191
Query 207 IRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVLG-FIVFLIWEMTD 265
R R D G L L + ++L E+ +S I L ++ +G +++++
Sbjct 192 ARRRFDITGFLLFGLSLVLFSSGIELFGEK--IVASWIALTVIVTSIGLLLLYILHARRT 249
Query 266 RLPVVNLWVFRHRGFTVSV---LALSFGFGAFFGSIVLIPQWLQMNLNYTATWAGYLTAT 322
P+++L +F+ R F++ + +A G G L+P LQ+ Y A AG + A
Sbjct 250 PNPLISLDLFKTRTFSIGIVGNIATRLGTGCV---PFLMPLMLQVGFGYQAFIAGCMMAP 306
Query 323 MGFGSLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAFWTSDADFMTLAWPQILQGF 382
GS++ +V ++ + R +++G + + + L P + G
Sbjct 307 TALGSIIAKSMVTQVLRRLGYRHTLVGITVIIGLMIAQFSLQSPAMAIWMLILPLFILGM 366
Query 383 AVPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIAVTIWDDHAKVARSEMV 442
A+ F ++ + L+ + +S ++ + ++ ++G +++ + + + + V
Sbjct 367 AMSTQFTAMNTITLADLTDDNASSGNSVLAVTQQLSISLGVAVSAAVLRVYEGMEGTTTV 426
Query 443 SNLH 446
H
Sbjct 427 EQFH 430
>P9WG91 Multidrug resistance protein Stp [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=537
Score = 171 bits (434), Expect = 3e-50
Identities = 117/406 (29%), Positives = 198/406 (49%), Gaps = 8/406 (2%)
Query 23 LLAAFVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWL 82
LL L FM+ LD I NV++P I + AV WVV SY++ A+ + L
Sbjct 6 LLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATL 65
Query 83 ASRFGTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTLLMRIFP 142
A G R +++G+ FT+ S CGL+ S+ +L R QGL + S L+ FP
Sbjct 66 ADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFP 125
Query 143 QEKH-SQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVLGTIRLLSV 201
+ K ++A+G+W +G GP LGGL+ D W IF++N+P+G + + T+ +
Sbjct 126 EAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEE 185
Query 202 AETETIRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVLGFIVFLIW 261
+ E R R D G L ++ +GAL + G + W + IV+ AV G +F+
Sbjct 186 SCNERAR-RFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAV-GCALFVWL 243
Query 262 EMTDRLPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVLIPQWLQMNLNYTATWAGYLTA 321
E P+++L +FR + +++ + F A +G ++L Q+LQ YT + G +
Sbjct 244 ERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMIL 303
Query 322 TMGFGSLMMSPVVAKLAAKYDPRA--LASFGLLLLGGVTLMRAFWTSDADFMTLAWPQIL 379
++SP+V L + R LA +L+LG + L+ + S A + L
Sbjct 304 PFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG---L 360
Query 380 QGFAVPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASI 425
G V P++ +A+++V + A+G+M+ R + IG ++
Sbjct 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAV 406
>P9WJY5 Uncharacterized MFS-type transporter EfpA [Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=530
Score = 166 bits (419), Expect = 3e-48
Identities = 110/406 (27%), Positives = 196/406 (48%), Gaps = 15/406 (4%)
Query 23 LLAAFVIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWL 82
+ A I + +D+T+A V++P I L++S + +WV+T+Y + + L G L
Sbjct 52 IAAVIAIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWVITAYVLTFGGLMLLGGRL 111
Query 83 ASRFGTVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTLLMRIFP 142
G R F++G+ FT+ S LC ++ LV+ R+ QG+ P L+ FP
Sbjct 112 GDTIGRKRTFIVGVALFTISSVLCAVAWDEATLVIARLSQGVGSAIASPTGLALVATTFP 171
Query 143 Q-EKHSQAMGLWAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVLGTIRLLSV 201
+ + A ++A T +G ++G ++GG +++ +SW W F +N+P+G++ + + ++
Sbjct 172 KGPARNAATAVFAAMTAIGSVMGLVVGGALTE-VSWRWAFLVNVPIGLVMIY--LARTAL 228
Query 202 AETETIRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVLGFIVFLIW 261
ET R+++DA G L L A +G E+ W S I + ++A+ + F+I
Sbjct 229 RETNKERMKLDATGAILATLACTAAVFAFSIGPEKGWM-SGITIGSGLVALAAAVAFVIV 287
Query 262 EMTDRLPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVLIPQWLQMNLNYTATWAGY--- 318
E T PVV +FR R V+ A+ G F V I ++Q L Y+A AG
Sbjct 288 ERTAENPVVPFHLFRDRNRLVTFSAILLAGGVMFSLTVCIGLYVQDILGYSALRAGVGFI 347
Query 319 -LTATMGFGSLMMSPVVAKLAAKYDPRALASFGLLLLGGVTLMRAFWTSDA--DFMTLAW 375
MG G V ++L +++ PR L G LL G L +F+ F L
Sbjct 348 PFVIAMGIG----LGVSSQLVSRFSPRVLTIGGGYLLFGAMLYGSFFMHRGVPYFPNLVM 403
Query 376 PQILQGFAVPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAI 421
P ++ G + +PL+ A++ V ++ + + L+++ G +
Sbjct 404 PIVVGGIGIGMAVVPLTLSAIAGVGFDQIGPVSAIALMLQSLGGPL 449
>P46105 Probable actinorhodin transporter [Streptomyces coelicolor
(strain ATCC BAA-471 / A3(2) / M145)]
Length=578
Score = 157 bits (398), Expect = 4e-45
Identities = 120/440 (27%), Positives = 211/440 (48%), Gaps = 27/440 (6%)
Query 28 VIALSNFMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWLASRFG 87
VI + M +LD T+ NV+ P + +L S S W+ Y +A A+ + + G L +G
Sbjct 46 VILGAEIMDLLDGTVMNVAAPAVRADLGGSLSVIQWITVGYTLAFAVLLVVGGRLGDIYG 105
Query 88 TVRVFVMGLIGFTVFSFLCGLSTSLEMLVLCRIGQGLSGGPLMPLSQTLLMRIFPQEKHS 147
R+FV+G +GFT S LC ++ EML R QG G ++P L+ ++FP ++ +
Sbjct 106 RKRMFVVGAVGFTAASVLCSVAAGPEMLTAARFLQGGLGALMIPQGLGLIKQMFPPKETA 165
Query 148 QAMGLWAMTTVLGPILGPILGGLISD----NLSWHWIFFINIPVGIICVLGTIRLLSVAE 203
A G + LG +LGPI+ G + D W +F IN+P+G+ ++G + LL +
Sbjct 166 AAFGAFGPAIGLGAVLGPIVAGFLVDADLFGTGWRSVFLINLPIGVAVIVGAVLLLPEGK 225
Query 204 TETIRVRIDAIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVL-GFIVF-LIW 261
+R + D +G+ L+ + L L G ER W + +++ A AVL GF+ L
Sbjct 226 A-PVRPKFDVVGMALVTSGLTLLIFPLVQGRERGWPAWAFVLMLAGAAVLVGFVAHELRQ 284
Query 262 EMTDRLPVVNLWVFRHRGFTVSVLALSFGFGAFFGSIVLIPQWLQMNLNYTATWAGYLTA 321
E ++ L + R + + F G +L+ LQ+ L ++ T A LT
Sbjct 285 ERRGGATLIELSLLRRSRYAAGLAVALVFFTGVSGMSLLLALHLQIGLGFSPTRAA-LTM 343
Query 322 TMGFGSLMMSPVV--AKLAAKYDPRALASFGLLLLGGVTLMRAFWTSDADFMTLAWPQI- 378
T L++ ++ A L +K+ +AL ++L GV +M A +T +W +
Sbjct 344 TPWSVFLVVGAILTGAVLGSKFGRKALHGGLVVLALGVLIMLLTIGDQAGGLT-SWELVP 402
Query 379 ---LQGFAVPFFFIPLSNLALSSVQPQELASAAGLMNFLRTMAGAIGASIAVTIW----- 430
+ G + L ++AL+ V QE +A+G++ ++ + +G ++ T++
Sbjct 403 GIAVAGLGMGIMIGLLFDIALADVDKQEAGTASGVLTAVQQLGFTVGVAVLGTLFFGLLG 462
Query 431 -------DDHAKVARSEMVS 443
DD A AR+E+ +
Sbjct 463 SQATASVDDGASRARTELAA 482
Lambda K H a alpha
0.328 0.140 0.434 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 3513510
Database: 02cb0e5cfbd3d25a4e2527a2a4ff91ba.SwissProt.fasta
Posted date: May 20, 2024 6:36 PM
Number of letters in database: 8,523
Number of sequences in database: 17
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
