BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 214b99bc98cc9e984428765dfcc2d6f0.SwissProt.fasta
6 sequences; 2,865 total letters
Query= ACIAD0963
Length=506
Score E
Sequences producing significant alignments: (Bits) Value
P75067 Nicotinamide phosphoribosyltransferase [Mycoplasma pneumon... 232 2e-74
Q52I78 Nicotinamide phosphoribosyltransferase [Sus scrofa] 223 2e-70
Q99KQ4 Nicotinamide phosphoribosyltransferase [Mus musculus] 221 9e-70
P43490 Nicotinamide phosphoribosyltransferase [Homo sapiens] 221 9e-70
Q80Z29 Nicotinamide phosphoribosyltransferase [Rattus norvegicus] 219 3e-69
P47283 Nicotinamide phosphoribosyltransferase [Mycoplasma genital... 213 3e-67
>P75067 Nicotinamide phosphoribosyltransferase [Mycoplasma pneumoniae
(strain ATCC 29342 / M129 / Subtype 1)]
Length=451
Score = 232 bits (592), Expect = 2e-74
Identities = 158/454 (35%), Positives = 219/454 (48%), Gaps = 45/454 (10%)
Query 8 LNAIDFYKADHRRQYPEGTEYVYANFTPRSSR--LANML--HDFDDKIVFFGLQGFIQHF 63
L A D YK HR YP T +Y+ T R R N + H+F KI+ F
Sbjct 15 LLACDAYKLSHRLMYPNDTTNLYSCLTARGGRGGFPNFVWNHEFAKKIILEVFGNFCDSV 74
Query 64 LIETWNEGFFNQ--DKATVVSHYKRRMDTSLGEGAVSVEHIEALHDLG-------YLPLK 114
L + G DK T V G+ +E + + L LPL
Sbjct 75 LAVQNDPGLAQALTDKVTTV----------FGDPQFGLEFTQHICYLANFLKQHHQLPLT 124
Query 115 IKALPEGSRVNMRVPVLTVINTQA---EFFWLTNYIETVLSAELWKSSTTATIAFEYKRL 171
+K + R P++T+ + E WL NY ETVL +W TT T+A K L
Sbjct 125 VKIHQSSEGLAFRTPLVTITGSDQMVPELVWLVNYFETVLLENIWLYQTTLTVAQSLKLL 184
Query 172 LTQYAVKTGASIENVVVQGHDFSSRGMSGIYDAAQSGVGHLTSFIGTDAVTAIDYAEQYY 231
L +YA +T + E Q HDFS RGMS + A HL F G+D +
Sbjct 185 LERYANETADNTEFTHFQCHDFSMRGMSSLQSALYVANAHLQYFSGSDTILG-------- 236
Query 232 AASGVVGVSVPATEHSVMCMGSEENELETFRRLICELYPSGIVSIVSDTWDFWRVLSEFS 291
GV S+ A+EHSVMC +E EL TF+RL+ E +P+ +S+V D++D W VL
Sbjct 237 ---GVAAKSILASEHSVMCADGQEGELNTFKRLL-EQFPNKNLSLVIDSYDMWHVLDNIL 292
Query 292 VKLKQDILNRTPNALGLAKVVFRPDSGDPVKIICGDPDAEKDTPAYKGAVQLLWEIFGGT 351
+LK +L R K+ RPDSG+ +IC + G + L FG T
Sbjct 293 PQLKDLVLQRQE------KLYLRPDSGNFETLICQGKRFNPEDKTTWGVIDYLDYHFGST 346
Query 352 YTAQGYKVLHERVGLIYGDSITLQRAEAILQGLEAQGFASSNLVFGIGSYTYNYMTRDTF 411
+GYKVL++++G++YGD IT +R E IL+ L+ +GF SSN+VFG+GS TY + RDT
Sbjct 347 VNQKGYKVLNQKLGIVYGDGITYERIEYILEQLKQRGFCSSNIVFGVGSTTYQNLNRDTL 406
Query 412 GFAVKATWGQVNGVGRELFKDPVTDSGTKKSAQG 445
GF K T + ++ K P+TD TK+S G
Sbjct 407 GFVYKLTAIKKGNTWHDVTKSPITDP-TKQSIGG 439
>Q52I78 Nicotinamide phosphoribosyltransferase [Sus scrofa]
Length=491
Score = 223 bits (568), Expect = 2e-70
Identities = 150/502 (30%), Positives = 255/502 (51%), Gaps = 34/502 (7%)
Query 6 NPLNAIDFYKADHRRQYPEGTEYVYANFTPRSSRLAN--MLHDFDDKIVFFGLQGFIQHF 63
N L A D YK H +QYP T VY+ F R + N + ++ VF+GLQ + +
Sbjct 10 NILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKIRKVKYEETVFYGLQYILNKY 69
Query 64 LI-ETWNEGFFNQDKATVVSHYKRRMDTSLGEGAVSVEHIEALHDLGYLPLKIKALPEGS 122
L + + + K H++ + G + ++ G+LP+++KA+PEGS
Sbjct 70 LKGKVVTKEKIQEAKEVYKEHFQDDVFNEKGWNYILEKYD------GHLPIEVKAVPEGS 123
Query 123 RVNMRVPVLTVINTQAEFFWLTNYIETVLSAELWKSSTTATIAFEYKRLLTQYAVKTGAS 182
+ + TV NT E +WLTN+IET+L + W T AT + E K++L +Y ++T +
Sbjct 124 VIPRGNVLFTVENTDPECYWLTNWIETIL-VQSWYPITVATNSREQKKILAKYLLETSGN 182
Query 183 IENVVVQGHDFSSRGMSGIYDAAQSGVGHLTSFIGTDAVTAIDYAEQYYAASGVV-GVSV 241
++ + + HDF RG+S A HL +F GTD V I ++YY V G SV
Sbjct 183 LDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGIALIKKYYGTKDPVPGYSV 242
Query 242 PATEHSVMCMGSEENELETFRRLICELYPSGIVSIVSDTWDFWRVLSE-FSVKLKQDILN 300
PA EHS + +++E + F ++ + + S VS+VSD++D + + + L+ I++
Sbjct 243 PAAEHSTITAWGKDHEKDAFEHIVTQ-FSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVS 301
Query 301 RTPNALGLAKVVFRPDSGDPVKIICGDPDAEKDTPAYKGAVQLLWEIFGGTYTAQGYKVL 360
R+ A ++ RPDSG+P+ + + +L + F T ++GYK+L
Sbjct 302 RSTEA----PLIIRPDSGNPLDTVLK-------------VLDILGKKFPVTENSKGYKLL 344
Query 361 HERVGLIYGDSITLQRAEAILQGLEAQGFASSNLVFGIGSYTYNYMTRDTFGFAVKATWG 420
+ +I GD + + + I++G++ + ++ N+ FG G +TRD + K ++
Sbjct 345 PPYLRVIQGDGVDINTLQEIVEGMKQKKWSIENIAFGSGGALLQKLTRDLLNCSFKCSYV 404
Query 421 QVNGVGRELFKDPVTDSGTKKSAQGLLRVERSQDG-FTLFDRQSKQQENQGE--LHTVFE 477
NG+G +FKDPV D K+S +G L + R+ G F + E G LHTVF+
Sbjct 405 VTNGLGINVFKDPVADP-NKRSKKGRLSLHRTPGGNFVTLEEGKGDLEEYGHDLLHTVFK 463
Query 478 NGQLCLKSTLDEIRQRLAQQLE 499
NG++ + DE+R+ +E
Sbjct 464 NGKVTKSYSFDEVRKNAQLNIE 485
>Q99KQ4 Nicotinamide phosphoribosyltransferase [Mus musculus]
Length=491
Score = 221 bits (563), Expect = 9e-70
Identities = 150/502 (30%), Positives = 255/502 (51%), Gaps = 34/502 (7%)
Query 6 NPLNAIDFYKADHRRQYPEGTEYVYANFTPRSSRLAN--MLHDFDDKIVFFGLQGFIQHF 63
N L A D YK H +QYP T VY+ F R + N + ++ VF+GLQ + +
Sbjct 10 NILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKVRKVKYEETVFYGLQYILNKY 69
Query 64 LI-ETWNEGFFNQDKATVVSHYKRRMDTSLGEGAVSVEHIEALHDLGYLPLKIKALPEGS 122
L + + + K H++ + G + ++ G+LP+++KA+PEGS
Sbjct 70 LKGKVVTKEKIQEAKEVYREHFQDDVFNERGWNYILEKYD------GHLPIEVKAVPEGS 123
Query 123 RVNMRVPVLTVINTQAEFFWLTNYIETVLSAELWKSSTTATIAFEYKRLLTQYAVKTGAS 182
+ + TV NT E +WLTN+IET+L + W T AT + E K++L +Y ++T +
Sbjct 124 VIPRGNVLFTVENTDPECYWLTNWIETIL-VQSWYPITVATNSREQKKILAKYLLETSGN 182
Query 183 IENVVVQGHDFSSRGMSGIYDAAQSGVGHLTSFIGTDAVTAIDYAEQYYAASGVV-GVSV 241
++ + + HDF RG+S A HL +F GTD V I ++YY V G SV
Sbjct 183 LDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGIALIKKYYGTKDPVPGYSV 242
Query 242 PATEHSVMCMGSEENELETFRRLICELYPSGIVSIVSDTWDFWRVLSE-FSVKLKQDILN 300
PA EHS + +++E + F ++ + + S VS+VSD++D + + + L+ I++
Sbjct 243 PAAEHSTITAWGKDHEKDAFEHIVTQ-FSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVS 301
Query 301 RTPNALGLAKVVFRPDSGDPVKIICGDPDAEKDTPAYKGAVQLLWEIFGGTYTAQGYKVL 360
R+ A ++ RPDSG+P+ + + +L + F T ++GYK+L
Sbjct 302 RSTEA----PLIIRPDSGNPLDTVLK-------------VLDILGKKFPVTENSKGYKLL 344
Query 361 HERVGLIYGDSITLQRAEAILQGLEAQGFASSNLVFGIGSYTYNYMTRDTFGFAVKATWG 420
+ +I GD + + + I++G++ + ++ N+ FG G +TRD + K ++
Sbjct 345 PPYLRVIQGDGVDINTLQEIVEGMKQKKWSIENVSFGSGGALLQKLTRDLLNCSFKCSYV 404
Query 421 QVNGVGRELFKDPVTDSGTKKSAQGLLRVERSQDG-FTLFDRQSKQQENQGE--LHTVFE 477
NG+G +FKDPV D K+S +G L + R+ G F + E G LHTVF+
Sbjct 405 VTNGLGVNVFKDPVADP-NKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGHDLLHTVFK 463
Query 478 NGQLCLKSTLDEIRQRLAQQLE 499
NG++ + DE+R+ +E
Sbjct 464 NGKVTKSYSFDEVRKNAQLNIE 485
>P43490 Nicotinamide phosphoribosyltransferase [Homo sapiens]
Length=491
Score = 221 bits (563), Expect = 9e-70
Identities = 150/502 (30%), Positives = 256/502 (51%), Gaps = 34/502 (7%)
Query 6 NPLNAIDFYKADHRRQYPEGTEYVYANFTPRSSRLAN--MLHDFDDKIVFFGLQGFIQHF 63
N L A D YK H +QYP T VY+ F R + N + ++ VF+GLQ + +
Sbjct 10 NILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKLRKVKYEETVFYGLQYILNKY 69
Query 64 LI-ETWNEGFFNQDKATVVSHYKRRMDTSLGEGAVSVEHIEALHDLGYLPLKIKALPEGS 122
L + + + K H++ + G + ++ G+LP++IKA+PEG
Sbjct 70 LKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYD------GHLPIEIKAVPEGF 123
Query 123 RVNMRVPVLTVINTQAEFFWLTNYIETVLSAELWKSSTTATIAFEYKRLLTQYAVKTGAS 182
+ + TV NT E +WLTN+IET+L + W T AT + E K++L +Y ++T +
Sbjct 124 VIPRGNVLFTVENTDPECYWLTNWIETIL-VQSWYPITVATNSREQKKILAKYLLETSGN 182
Query 183 IENVVVQGHDFSSRGMSGIYDAAQSGVGHLTSFIGTDAVTAIDYAEQYYAASGVV-GVSV 241
++ + + HDF RG+S A HL +F GTD V + ++YY V G SV
Sbjct 183 LDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSV 242
Query 242 PATEHSVMCMGSEENELETFRRLICELYPSGIVSIVSDTWDFWRVLSE-FSVKLKQDILN 300
PA EHS + +++E + F ++ + + S VS+VSD++D + + + L+ I++
Sbjct 243 PAAEHSTITAWGKDHEKDAFEHIVTQ-FSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVS 301
Query 301 RTPNALGLAKVVFRPDSGDPVKIICGDPDAEKDTPAYKGAVQLLWEIFGGTYTAQGYKVL 360
R+ A ++ RPDSG+P+ + +++L + F T ++GYK+L
Sbjct 302 RSTQA----PLIIRPDSGNPLDTVLK-------------VLEILGKKFPVTENSKGYKLL 344
Query 361 HERVGLIYGDSITLQRAEAILQGLEAQGFASSNLVFGIGSYTYNYMTRDTFGFAVKATWG 420
+ +I GD + + + I++G++ + ++ N+ FG G +TRD + K ++
Sbjct 345 PPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYV 404
Query 421 QVNGVGRELFKDPVTDSGTKKSAQGLLRVERSQDG-FTLFDRQSKQQENQGE--LHTVFE 477
NG+G +FKDPV D K+S +G L + R+ G F + E G+ LHTVF+
Sbjct 405 VTNGLGINVFKDPVADP-NKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFK 463
Query 478 NGQLCLKSTLDEIRQRLAQQLE 499
NG++ + DEIR+ +E
Sbjct 464 NGKVTKSYSFDEIRKNAQLNIE 485
>Q80Z29 Nicotinamide phosphoribosyltransferase [Rattus norvegicus]
Length=491
Score = 219 bits (559), Expect = 3e-69
Identities = 149/502 (30%), Positives = 255/502 (51%), Gaps = 34/502 (7%)
Query 6 NPLNAIDFYKADHRRQYPEGTEYVYANFTPRSSRLAN--MLHDFDDKIVFFGLQGFIQHF 63
N L A D YK H +QYP T VY+ F R + N + ++ VF+GLQ + +
Sbjct 10 NILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKVRKVKYEETVFYGLQYILNKY 69
Query 64 LI-ETWNEGFFNQDKATVVSHYKRRMDTSLGEGAVSVEHIEALHDLGYLPLKIKALPEGS 122
L + + + K H++ + G + ++ G+LP+++KA+PEGS
Sbjct 70 LKGKVVTKEKIQEAKEVYREHFQDDVFNERGWNYILEKYD------GHLPIEVKAVPEGS 123
Query 123 RVNMRVPVLTVINTQAEFFWLTNYIETVLSAELWKSSTTATIAFEYKRLLTQYAVKTGAS 182
+ + TV NT E +WLTN+IET+L + W T AT + E K++L +Y ++T +
Sbjct 124 VIPRGNVLFTVENTDPECYWLTNWIETIL-VQSWYPITVATNSREQKKILAKYLLETSGN 182
Query 183 IENVVVQGHDFSSRGMSGIYDAAQSGVGHLTSFIGTDAVTAIDYAEQYYAASGVV-GVSV 241
++ + + HDF RG+S A HL +F GTD V I ++YY V G SV
Sbjct 183 LDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGIALIKKYYGTKDPVPGYSV 242
Query 242 PATEHSVMCMGSEENELETFRRLICELYPSGIVSIVSDTWDFWRVLSE-FSVKLKQDILN 300
PA EHS + +++E + F ++ + + S VS+VSD++D + + + L+ I++
Sbjct 243 PAAEHSTITAWGKDHEKDAFEHIVTQ-FSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVS 301
Query 301 RTPNALGLAKVVFRPDSGDPVKIICGDPDAEKDTPAYKGAVQLLWEIFGGTYTAQGYKVL 360
R+ A ++ RPDSG+P+ + + +L + F + ++GYK+L
Sbjct 302 RSTEA----PLIIRPDSGNPLDTVLK-------------VLDILGKKFPVSENSKGYKLL 344
Query 361 HERVGLIYGDSITLQRAEAILQGLEAQGFASSNLVFGIGSYTYNYMTRDTFGFAVKATWG 420
+ +I GD + + + I++G++ + ++ N+ FG G +TRD + K ++
Sbjct 345 PPYLRVIQGDGVDINTLQEIVEGMKQKKWSIENVSFGSGGALLQKLTRDLLNCSFKCSYV 404
Query 421 QVNGVGRELFKDPVTDSGTKKSAQGLLRVERSQDG-FTLFDRQSKQQENQGE--LHTVFE 477
NG+G +FKDPV D K+S +G L + R+ G F + E G LHTVF+
Sbjct 405 VTNGLGVNVFKDPVADP-NKRSKKGRLSLHRTPAGTFVTLEEGKGDLEEYGHDLLHTVFK 463
Query 478 NGQLCLKSTLDEIRQRLAQQLE 499
NG++ + DE+R+ +E
Sbjct 464 NGKVTKSYSFDEVRKNAQLNME 485
>P47283 Nicotinamide phosphoribosyltransferase [Mycoplasma genitalium
(strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)]
Length=450
Score = 213 bits (543), Expect = 3e-67
Identities = 157/470 (33%), Positives = 229/470 (49%), Gaps = 52/470 (11%)
Query 1 MSFRINPLNAIDFYKADHRRQYPEGTEYVYANFTPRSSRLANMLHDFDDKIVFFGLQGFI 60
+ F + L A D YK HR YP+ T+ +Y+ T R + DF + F F
Sbjct 9 IEFHLKNLLACDAYKLSHRLMYPQDTQNLYSMLTARG-----VYGDFKE---FVWNHDFA 60
Query 61 QHFLIETWNEGFFNQDKATVVSHYKRRM-DTSLGEGAVSV-----------EHI----EA 104
+ L+ +N GF N +V+ K ++ +L + VSV +HI
Sbjct 61 KEILLNVFN-GFVN----SVIEVKKNKLLAAALTDKLVSVFNDHELANEFTQHICHLASF 115
Query 105 LHDLGYLPLKIKALPEGSRVNMRVPVLT---VINTQAEFFWLTNYIETVLSAELWKSSTT 161
L +PL K + R P++T V N F WL NY ETVL +W T
Sbjct 116 LEKNKKMPLVAKIHESDQSLPFRTPLITIEGVENIPNNFVWLVNYFETVLLENIWLFQTA 175
Query 162 ATIAFEYKRLLTQYAVKTGASIENVVVQGHDFSSRGMSGIYDAAQSGVGHLTSFIGTDAV 221
+T+A K LL +YA +T + Q HDFS RGMS + A HL F G+D +
Sbjct 176 STVAKRIKSLLEKYAKETADETSFINFQCHDFSMRGMSSLQSALYVARAHLQYFTGSDTI 235
Query 222 TAIDYAEQYYAASGVVGVSVPATEHSVMCMGSEENELETFRRLICELYPSGIVSIVSDTW 281
D + S+ A+EHSVMC ++EL+TF+RL+ E + +S+V D++
Sbjct 236 LGGDNSR-----------SILASEHSVMCADGSKHELKTFQRLL-EKFKDKKLSLVIDSY 283
Query 282 DFWRVLSEFSVKLKQDILNRTPNALGLAKVVFRPDSGDPVKIICGDPDAEKDTPAYKGAV 341
D W VL +LK IL R A + R DSG+ +IC +P+ +K + +
Sbjct 284 DMWNVLDNIIPRLKNLILMRG------ATLYLRADSGNYQTLIC-NPNYKKQDKSTWAMI 336
Query 342 QLLWEIFGGTYTAQGYKVLHERVGLIYGDSITLQRAEAILQGLEAQGFASSNLVFGIGSY 401
L F T +GYKVL++++G+IYGD IT Q+ E IL L+ G+ SSN++FG+GS
Sbjct 337 DYLDHHFSSTINKKGYKVLNKKIGIIYGDGITYQKIEWILNCLKNHGYCSSNIIFGVGSS 396
Query 402 TYNYMTRDTFGFAVKATWGQVNGVGRELFKDPVTDSGTKKSAQGLLRVER 451
TY + RDT GF K T + N + K P+TD +K S G + +R
Sbjct 397 TYQNLNRDTLGFVYKLTAIKRNNRWIGVKKTPITDL-SKSSKGGRYKTKR 445
Score = 17.3 bits (33), Expect = 7.6
Identities = 11/29 (38%), Positives = 16/29 (55%), Gaps = 5/29 (17%)
Query 477 ENGQLCLKSTLDEIR--QRLAQQLESFKD 503
E+ +C + E++ QRL LE FKD
Sbjct 248 EHSVMCADGSKHELKTFQRL---LEKFKD 273
Lambda K H a alpha
0.320 0.136 0.402 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1190940
Database: 214b99bc98cc9e984428765dfcc2d6f0.SwissProt.fasta
Posted date: Jun 2, 2024 1:31 AM
Number of letters in database: 2,865
Number of sequences in database: 6
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
