BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: da854e4ef87c86c17f0670d940c87e58.SwissProt.fasta
22 sequences; 9,732 total letters
Query= ACIAD1040
Length=422
Score E
Sequences producing significant alignments: (Bits) Value
Q8NMT3 Glutaminase [Corynebacterium glutamicum (strain ATCC 13032... 370 4e-129
Q8FMX4 Glutaminase [Corynebacterium efficiens (strain DSM 44549 /... 351 1e-121
Q89KV2 Glutaminase 2 [Bradyrhizobium diazoefficiens (strain JCM 1... 295 5e-97
Q89NA7 Glutaminase 1 [Bradyrhizobium diazoefficiens (strain JCM 1... 292 3e-96
Q3MEJ6 Glutaminase [Trichormus variabilis (strain ATCC 29413 / PC... 258 2e-86
B0JPM4 Glutaminase [Microcystis aeruginosa (strain NIES-843 / IAM... 258 3e-86
Q8YSZ5 Glutaminase [Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTE... 255 4e-85
B0C9Y4 Glutaminase [Acaryochloris marina (strain MBIC 11017)] 241 6e-80
Q898A3 Glutaminase [Clostridium tetani (strain Massachusetts / E88)] 240 8e-80
A0PTH3 Glutaminase [Mycobacterium ulcerans (strain Agy99)] 231 4e-76
B2HGL4 Glutaminase [Mycobacterium marinum (strain ATCC BAA-535 / M)] 231 4e-76
P77454 Glutaminase 1 [Escherichia coli (strain K12)] 219 1e-71
P13264 Glutaminase kidney isoform, mitochondrial [Rattus norvegicus] 218 1e-67
D3Z7P3 Glutaminase kidney isoform, mitochondrial [Mus musculus] 218 1e-67
O94925 Glutaminase kidney isoform, mitochondrial [Homo sapiens] 217 3e-67
Q571F8 Glutaminase liver isoform, mitochondrial [Mus musculus] 206 1e-63
P28492 Glutaminase liver isoform, mitochondrial [Rattus norvegicus] 206 2e-63
Q9UI32 Glutaminase liver isoform, mitochondrial [Homo sapiens] 204 6e-63
O07637 Glutaminase 2 [Bacillus subtilis (strain 168)] 192 3e-61
O31465 Glutaminase 1 [Bacillus subtilis (strain 168)] 191 1e-60
O87405 Thermolabile glutaminase [Rhizobium etli (strain CFN 42 / ... 190 2e-60
P0A6W0 Glutaminase 2 [Escherichia coli (strain K12)] 169 2e-52
>Q8NMT3 Glutaminase [Corynebacterium glutamicum (strain ATCC 13032
/ DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
10025)]
Length=413
Score = 370 bits (950), Expect = 4e-129
Identities = 196/397 (49%), Positives = 261/397 (66%), Gaps = 5/397 (1%)
Query 4 PVPEYLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQ 63
P+PEYL ++D + +G+LADYIPEL A+P+ +A+A+ TV+G IY+ GD+DIEFT+Q
Sbjct 5 PIPEYLHEILDDVRDTTSGELADYIPELKSADPNPLAVALCTVNGHIYSAGDDDIEFTMQ 64
Query 64 SMSKPFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTHSLI 123
S+SKPF YA LQ+ G DEV V +EPSGEAFNE+SL + RP NPMIN+GAI + LI
Sbjct 65 SISKPFAYALALQECGFDEVSASVALEPSGEAFNELSLDGENRPMNPMINAGAIAINQLI 124
Query 124 PIKDQL--ESAEIIRRFMSELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDP 181
D + E IR + SELAGREL D + SE+ A RNLSI +MLR G++E +
Sbjct 125 NGSDSTVEDRVEKIRHYFSELAGRELTIDRVLAESELAGADRNLSIAHMLRNYGVIEDEA 184
Query 182 VDIVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYD 241
D V Y QC+I VT +DL M + LA GG TGK+LL+ V R LSVM S GMYD
Sbjct 185 HDAVLSYTLQCAIKVTTRDLAVMTATLAAGGTHPITGKKLLDARVCRLTLSVMASAGMYD 244
Query 242 AAGDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGL 301
AG WL+TVGIPAKSGVAGG++G+LPGQ+ IA FSPRL+ GNSVRG+++ ++LS DMGL
Sbjct 245 EAGQWLSTVGIPAKSGVAGGLIGILPGQLGIATFSPRLNPKGNSVRGVKIFKQLSDDMGL 304
Query 302 HLMEGTPSAQTIVQSHYRTGKNASTSIYVLRGVLKFTEAEMLLRIFQGEAVDESTIVIDL 361
HLM + V+S R G T+ ++G + F+ +E L + + +V+DL
Sbjct 305 HLMSTEQVSGHAVRSITRDG---DTTFIQMQGAMNFSASESFLHAIVEHNFEGTEVVLDL 361
Query 362 TQISLIHDVGKRMFLEGVDRLIDDGHSVLLVDPEQRL 398
T++ H V RM EG+ R+ D G V ++DP+ L
Sbjct 362 TRVLSFHPVAIRMIKEGLKRIRDAGFEVFILDPDDVL 398
>Q8FMX4 Glutaminase [Corynebacterium efficiens (strain DSM 44549
/ YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)]
Length=423
Score = 351 bits (901), Expect = 1e-121
Identities = 189/402 (47%), Positives = 261/402 (65%), Gaps = 14/402 (3%)
Query 4 PVPEYLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQ 63
P+PEY +++ ++ +G++A YIP+L A+P+ +ALAM TVDG IY GD++ EFT+Q
Sbjct 9 PIPEYFEEILESVRSDVSGEVAQYIPQLKDADPNPLALAMCTVDGHIYGAGDDEHEFTMQ 68
Query 64 SMSKPFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISL-GHDKRPKNPMINSGAITTHSL 122
S+SKPF YA LQ+ G ++V VG+EPSGEAFNE+SL G RP NPMIN+GAI + L
Sbjct 69 SVSKPFAYALALQEQGPEKVFATVGLEPSGEAFNELSLDGSTNRPMNPMINAGAIAVNQL 128
Query 123 I-----PIKDQLESAEIIRRFMSELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGIL 177
I ++D++E IR + S LAGREL D + +EI+ A RNLSI +MLR GI+
Sbjct 129 INGSESSVEDRVEK---IRSYFSALAGRELNIDRQLSETEIEGADRNLSIAHMLRNYGII 185
Query 178 ETDPVDIVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSC 237
E D D V Y QCS+ VT +DL M + LA GG TG++L++ V R VLS M S
Sbjct 186 EDDAHDAVLSYTLQCSVKVTARDLAVMTATLAAGGTQPLTGEKLVDARVARLVLSTMASA 245
Query 238 GMYDAAGDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSR 297
GMYD AG WL TVGIPAKSGV+GG++GVLPGQ+ +A FSPRL+ GN VRG+E+ + LS
Sbjct 246 GMYDEAGQWLATVGIPAKSGVSGGLVGVLPGQLGLATFSPRLNSQGNPVRGVEIFKALSE 305
Query 298 DMGLHLMEGTPSAQTIVQSHYRT-GKNASTSIYVLRGVLKFTEAEMLLRIFQGEAVDEST 356
DMGLHLM SA+ + Q R + T++ L+G + F+ AE L
Sbjct 306 DMGLHLM----SAELLTQHAVRAIEERGDTTVIQLQGAMNFSAAENFLFTVTDHDFTGEK 361
Query 357 IVIDLTQISLIHDVGKRMFLEGVDRLIDDGHSVLLVDPEQRL 398
+V+D++++ + +G+R+ EG+ R+ D+G V + DPE L
Sbjct 362 VVLDISRVPMFRPMGRRLVKEGLRRIRDNGFKVAIYDPEDIL 403
>Q89KV2 Glutaminase 2 [Bradyrhizobium diazoefficiens (strain JCM
10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)]
Length=624
Score = 295 bits (754), Expect = 5e-97
Identities = 171/440 (39%), Positives = 243/440 (55%), Gaps = 23/440 (5%)
Query 4 PVPEYLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQ 63
P+ +L ++ + +G+LADYIPEL ANPD +A+ T+DG +Y VGD + FTIQ
Sbjct 25 PLRRFLTDCHEEFRGDSSGELADYIPELKRANPDHFGIALVTIDGHVYEVGDSAVPFTIQ 84
Query 64 SMSKPFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTHSLI 123
S+SK F +A L+ +G + V +GVEPSGEAFN I L +D RP NPM+N+GAI LI
Sbjct 85 SVSKAFVFALALETVGEERVSATIGVEPSGEAFNSIRLTNDNRPFNPMVNAGAIACSGLI 144
Query 124 PIKDQLESAEIIRRFMSELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDPVD 183
D + E +R +SE AGREL DEAV+ASE T RN +I ++LR +L D
Sbjct 145 YEVDGKGAFERVRSKLSEFAGRELGVDEAVHASETATGNRNRAIAWLLRNYAVLPDDVDA 204
Query 184 IVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAA 243
+++ Y RQC+ILVT +DL M + LAN GI+ TG +++ +V + LSVM S GMYD A
Sbjct 205 VLDVYFRQCAILVTARDLAVMAATLANRGINPVTGAQVITPHIVARTLSVMTSSGMYDYA 264
Query 244 GDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGLHL 303
G+W VGIPAKSGV GGI+ LP Q+ + FSP LD H NSVRG+++ E LS LH+
Sbjct 265 GEWTYRVGIPAKSGVGGGIVAALPSQLGLGTFSPLLDNHFNSVRGLKVCEALSARFDLHM 324
Query 304 MEGTPSAQTIVQSHYRT------------------GKNASTSIYVLRGVLKFTEAEMLLR 345
+ +T V + Y +++ I L G L F + + R
Sbjct 325 LNRNADVRTSVMADYDVYGISSRRSRQPHEQQILDERHSDIRIVELVGALNFGTIDYVTR 384
Query 346 IFQGEAVDESTIVIDLTQISLIHDVGKRMFLEGVDRLIDDGHSVLLVDPEQRLE-----Q 400
E + ++ID ++ I G + E + L + + +L E+
Sbjct 385 RLTSEPPNAPLLIIDFRRVPDITAAGAELLGETLTALGNANVTTILSGLEEASAVWAAIA 444
Query 401 ARTHKDRVLHVYQNMDELLE 420
ART R L + +D+ +E
Sbjct 445 ARTGDPRRLRRFALLDDAIE 464
>Q89NA7 Glutaminase 1 [Bradyrhizobium diazoefficiens (strain JCM
10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)]
Length=613
Score = 292 bits (748), Expect = 3e-96
Identities = 156/397 (39%), Positives = 233/397 (59%), Gaps = 19/397 (5%)
Query 4 PVPEYLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQ 63
P+ +L +++ +G +ADYIPEL +A+P ++++T+DG +Y VGD + FTIQ
Sbjct 15 PLLRFLDTCLNEFSAETSGAVADYIPELGNADPAYFGISLATLDGHVYEVGDSRVPFTIQ 74
Query 64 SMSKPFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTHSLI 123
SMSKPF +A L LG V +GVEPSG+ FN I L D P NPM+N+GAI LI
Sbjct 75 SMSKPFVFALALDLLGAGRVESAIGVEPSGDPFNSIRLNSDNHPFNPMVNAGAIACTGLI 134
Query 124 PIKDQLESAEIIRRFMSELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDPVD 183
E+ E IR +S AGR+L DEAVY+SE +T RN +IGY+L+T ++ +
Sbjct 135 YDSKGAEAFEQIRLALSRFAGRDLAVDEAVYSSESQTGDRNRAIGYLLKTNAVISDNVAA 194
Query 184 IVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAA 243
+++ Y RQC++LVT +D+ M + LAN GI+ TG+++++ + + LSVM S GMYD A
Sbjct 195 VLDVYFRQCAVLVTARDIAVMAATLANRGINPVTGEQVMSAYAISRTLSVMTSSGMYDYA 254
Query 244 GDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGLHL 303
G+W+ +GIPAKSGV GGIL LP ++ + ++SP+LD+HGNSVRGI++ E LS LH+
Sbjct 255 GEWIYRIGIPAKSGVGGGILAALPARLGLGSYSPKLDKHGNSVRGIKVCEALSSHYDLHM 314
Query 304 MEGTPSAQTIVQSHYRTGKNAS------------------TSIYVLRGVLKFTEAEMLLR 345
+ + A+ V + Y GK+ S I L G L + + + R
Sbjct 315 LNRSDDARNAVIADYDIGKSPSRRVRRAQEREILAAHEQEVRIIELVGTLSLSAVDYVSR 374
Query 346 IFQGEAVDESTIVIDLTQISLIHDVGKRMFLEGVDRL 382
G + ++ DL +++ G R+ E + L
Sbjct 375 RLAGRPRPQ-FVIFDLHRVTSTTRAGARLVAEAFEEL 410
>Q3MEJ6 Glutaminase [Trichormus variabilis (strain ATCC 29413
/ PCC 7937)]
Length=334
Score = 258 bits (659), Expect = 2e-86
Identities = 131/285 (46%), Positives = 186/285 (65%), Gaps = 1/285 (0%)
Query 22 GKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSKPFTYAYVLQQLGLD 81
G +A+YIPELA NPD ++++ TVDGQ+Y VGD FTIQS+SK F Y L+ G D
Sbjct 34 GIVANYIPELAKVNPDLFSISIVTVDGQVYQVGDYQQLFTIQSISKVFAYGLALEDHGRD 93
Query 82 EVLDKVGVEPSGEAFNEISLGHD-KRPKNPMINSGAITTHSLIPIKDQLESAEIIRRFMS 140
VL +VGVEP+GEAFN I L KRP NPM+N+GAI T SLI E +
Sbjct 94 YVLTRVGVEPTGEAFNSIILDEQSKRPYNPMVNAGAIATTSLIKGAGATERLNRVLEMFR 153
Query 141 ELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDPVDIVNGYIRQCSILVTVKD 200
G ++ D +V+ SE T +RN ++ +++ G+++ + + ++ Y +QC+++V D
Sbjct 154 RYIGHDVFVDISVFTSERSTGHRNRAMAHLMLNFGMIDRNLEEALDLYFQQCAVMVNCHD 213
Query 201 LVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAAGDWLTTVGIPAKSGVAG 260
L M + LAN G++ TG++ +N ++ +LSVM +CGMY+ AG+W VGIPAKSGV G
Sbjct 214 LAVMAATLANRGVNPVTGEQAVNSRYIKDILSVMYTCGMYNFAGEWAYKVGIPAKSGVCG 273
Query 261 GILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGLHLME 305
GI+ V+P Q+ IA FSP LD GNSVRG+++ E LS+ +GLHL E
Sbjct 274 GIMAVVPNQMGIAVFSPPLDIRGNSVRGVKVCEELSQQLGLHLFE 318
>B0JPM4 Glutaminase [Microcystis aeruginosa (strain NIES-843 /
IAM M-2473)]
Length=338
Score = 258 bits (659), Expect = 3e-86
Identities = 135/301 (45%), Positives = 189/301 (63%), Gaps = 1/301 (0%)
Query 4 PVPEYLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQ 63
P YL ++ D+ + QTGK+ADYIPELA A P +++ T DGQI+ VGD FT+Q
Sbjct 20 PFRNYLNYLHDKYSDLQTGKIADYIPELALAAPQWFGISVITTDGQIFEVGDCQQTFTVQ 79
Query 64 SMSKPFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISLGHD-KRPKNPMINSGAITTHSL 122
S+SK F + L+ G + V KVGVEP+GEAFN I L RP NPM+N+GAI T L
Sbjct 80 SISKAFVFGLALEDHGREYVNSKVGVEPTGEAFNSIILDEKTNRPYNPMVNAGAIATTDL 139
Query 123 IPIKDQLESAEIIRRFMSELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDPV 182
I ++ E + I GR+ + V+ SE T RN ++ Y++ G++
Sbjct 140 ITGQNATERLKRILEMFKRYTGRDHEINVPVFLSEKSTGNRNRAMAYLMLNFGMVSDKIE 199
Query 183 DIVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDA 242
+ ++ Y +QC+ILV DL M + LANGG++ TG R ++ V+ V+SVM++CGMYDA
Sbjct 200 ETLDLYCQQCAILVHAHDLALMAATLANGGVNPITGIRAIDEHYVQDVISVMLTCGMYDA 259
Query 243 AGDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGLH 302
+G+W VG+PAKSGV GGI V+P Q+ I FSP LDE GNS+RG+++ + +S D GLH
Sbjct 260 SGEWAYRVGLPAKSGVGGGITAVVPHQLGIGTFSPLLDEKGNSIRGVKICQNISEDFGLH 319
Query 303 L 303
L
Sbjct 320 L 320
>Q8YSZ5 Glutaminase [Nostoc sp. (strain PCC 7120 / SAG 25.82 /
UTEX 2576)]
Length=334
Score = 255 bits (651), Expect = 4e-85
Identities = 131/304 (43%), Positives = 195/304 (64%), Gaps = 1/304 (0%)
Query 3 TPVPEYLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTI 62
+P+ + + + + ++ + G +A+YIPELA NPD ++++ TVDGQ+Y VGD FTI
Sbjct 15 SPLLKVINDLHSKYKSLKEGIVANYIPELAKVNPDLFSISIVTVDGQVYQVGDYQQLFTI 74
Query 63 QSMSKPFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISLGHD-KRPKNPMINSGAITTHS 121
QS+SK F Y L+ G D VL +VGVEP+GEAFN I L KRP NPM+N+GAI T S
Sbjct 75 QSISKVFAYGLALEDHGRDYVLTRVGVEPTGEAFNAIILDEQSKRPYNPMVNAGAIATTS 134
Query 122 LIPIKDQLESAEIIRRFMSELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDP 181
LI E + G ++ D +V+ SE T +RN ++ +++ G+++ +
Sbjct 135 LIKGAGATERLNRVLEMFRRYIGHDVFVDISVFTSERSTGHRNRAMAHLMLNFGMIDRNI 194
Query 182 VDIVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYD 241
+ ++ Y +QC+++V DL M + LAN G++ TG++ +N ++ +LSVM +CGMY+
Sbjct 195 EEALDLYFQQCAVMVNCHDLAVMAATLANRGVNPITGEQAVNSRYIKDILSVMYTCGMYN 254
Query 242 AAGDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGL 301
AG+W VGIPAKSGV GGI+ V+P + IA FSP LD GNSVRG+++ E LS+ +GL
Sbjct 255 FAGEWAYKVGIPAKSGVCGGIMAVVPNLMGIAVFSPPLDIRGNSVRGVKVCEELSQQLGL 314
Query 302 HLME 305
HL E
Sbjct 315 HLFE 318
>B0C9Y4 Glutaminase [Acaryochloris marina (strain MBIC 11017)]
Length=321
Score = 241 bits (615), Expect = 6e-80
Identities = 129/286 (45%), Positives = 181/286 (63%), Gaps = 2/286 (1%)
Query 22 GKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSKPFTYAYVLQQLGLD 81
G+LA YIPEL A+P+ A+++ T DGQ + VG+ FTIQS+SK F Y L G D
Sbjct 21 GQLACYIPELCKADPNWFAISIVTTDGQTFQVGNCQQTFTIQSISKVFVYGMALADHGQD 80
Query 82 EVLDKVGVEPSGEAFNE-ISLGHD-KRPKNPMINSGAITTHSLIPIKDQLESAEIIRRFM 139
+L KVGVEP+G+ FN I L D KRP NPMIN+GAI T SLI + +
Sbjct 81 ALLAKVGVEPTGDPFNSLIRLDEDSKRPDNPMINAGAIATTSLIRGNGPTDRLNRLLEMF 140
Query 140 SELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDPVDIVNGYIRQCSILVTVK 199
G E+ D V+ SE T +RN +I +++ G+++ + + ++ Y +QCS+LV
Sbjct 141 RRYVGHEVFIDMPVFMSERDTGHRNRAIAHLMLNFGMIDKNIDEALDLYFQQCSVLVNCH 200
Query 200 DLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAAGDWLTTVGIPAKSGVA 259
DL M + LA+ GI+ T +R + V+ +LSVM +CGMYD AG+W VG+PAKSGV+
Sbjct 201 DLAVMAATLAHKGINPITQERAVESGYVKDILSVMYTCGMYDFAGEWAYKVGLPAKSGVS 260
Query 260 GGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGLHLME 305
GGI+ V+P + IA FSP LDE+GNS+RG ++E LS+ +GLHL +
Sbjct 261 GGIMAVVPNRAGIAVFSPLLDEYGNSIRGRRVLEALSQKLGLHLFD 306
>Q898A3 Glutaminase [Clostridium tetani (strain Massachusetts
/ E88)]
Length=306
Score = 240 bits (613), Expect = 8e-80
Identities = 126/297 (42%), Positives = 188/297 (63%), Gaps = 5/297 (2%)
Query 12 VIDQCEN-NQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSKPFT 70
+I++C + G++A YIPEL A+ D + + + +DG + GD D +FTIQS+SK
Sbjct 9 IIEECRKYTREGEVASYIPELKKADKDALGIYIDKLDGNEFCAGDYDTKFTIQSISKIIA 68
Query 71 YAYVLQQLGLDEVLDKVGVEPSGEAFNEI---SLGHDKRPKNPMINSGAITTHSLIPIKD 127
+ G+++VL KVGVEPS +FN I + + +P NPMIN+GAI T SLI
Sbjct 69 LIIAIMDNGMEKVLSKVGVEPSAYSFNSIVTLEVKNANKPLNPMINAGAIATVSLIKGNS 128
Query 128 QLESAEIIRRFMSELAG-RELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDPVDIVN 186
E E I F ++ G + + +E VY SE KT RN S+ Y ++ GI+E D +++
Sbjct 129 PEEIIERILEFTRKVTGNKNIKVNEEVYQSEKKTGDRNRSLAYFMKGTGIIEKDVEKVLD 188
Query 187 GYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAAGDW 246
Y +QCSI VT KD+ K+ S LAN G+ +TG+R++ +V + V +VM++CGMYDA+G +
Sbjct 189 AYFQQCSIEVTCKDIAKIASFLANDGVLPSTGERIIPAEVAKIVKAVMVTCGMYDASGSF 248
Query 247 LTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGLHL 303
VGIP+KSGV GGIL +PG + I F P LD+ GNS+ G++++ERLS ++ L +
Sbjct 249 AVKVGIPSKSGVGGGILATVPGVMGIGVFGPALDKKGNSIAGVKILERLSEELNLSI 305
>A0PTH3 Glutaminase [Mycobacterium ulcerans (strain Agy99)]
Length=320
Score = 231 bits (589), Expect = 4e-76
Identities = 126/289 (44%), Positives = 181/289 (63%), Gaps = 2/289 (1%)
Query 17 ENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSKPFTYAYVLQ 76
+N GK ADYIP LA ++++TVDGQ++ GD EF ++S+SK FT A V++
Sbjct 23 KNKHGGKNADYIPILAQVPSTLFGVSVATVDGQVFTAGDAGYEFALESISKIFTLALVIE 82
Query 77 QLGLDEVLDKVGVEPSGEAFNEISLG--HDKRPKNPMINSGAITTHSLIPIKDQLESAEI 134
Q G E+ KVG +P+GEAFN + H+ +P +P++N+GAI+T SL+ +
Sbjct 83 QRGPRELRLKVGADPTGEAFNSVLALELHNDKPMSPLVNAGAISTTSLVDAVGPEDRWRQ 142
Query 135 IRRFMSELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDPVDIVNGYIRQCSI 194
I S+ AGR++ E + ASE T + N +I ++LR G + DP++ + Y RQCS
Sbjct 143 IVGAQSDFAGRQISISEEINASEQATNFHNRAIAWLLRGSGYIYCDPMEACDIYTRQCST 202
Query 195 LVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAAGDWLTTVGIPA 254
LVT DL MG+ LANGG + TGKR++ R V VL+ M G+Y +GDW TVG+PA
Sbjct 203 LVTTADLAVMGATLANGGTNPITGKRVIARKNVPHVLAEMTMEGVYTRSGDWAYTVGLPA 262
Query 255 KSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGLHL 303
KSGV GG++ V PGQ++IAAFSP LD+ GNSVR + +++ + L L
Sbjct 263 KSGVGGGLVAVAPGQLAIAAFSPPLDKVGNSVRAQAAVAQIADTLQLGL 311
>B2HGL4 Glutaminase [Mycobacterium marinum (strain ATCC BAA-535
/ M)]
Length=320
Score = 231 bits (589), Expect = 4e-76
Identities = 126/289 (44%), Positives = 181/289 (63%), Gaps = 2/289 (1%)
Query 17 ENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSKPFTYAYVLQ 76
+N GK ADYIP LA ++++TVDGQ++ GD EF ++S+SK FT A V++
Sbjct 23 KNKHGGKNADYIPILAQVPSTLFGVSVATVDGQVFTAGDAGYEFALESISKIFTLALVIE 82
Query 77 QLGLDEVLDKVGVEPSGEAFNEISLG--HDKRPKNPMINSGAITTHSLIPIKDQLESAEI 134
Q G E+ KVG +P+GEAFN + H+ +P +P++N+GAI+T SL+ +
Sbjct 83 QRGPRELRLKVGADPTGEAFNSVLALELHNDKPMSPLVNAGAISTTSLVDAVGPEDRWRQ 142
Query 135 IRRFMSELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDPVDIVNGYIRQCSI 194
I S+ AGR++ E + ASE T + N +I ++LR G + DP++ + Y RQCS
Sbjct 143 IVGAQSDFAGRQISISEEINASEQATNFHNRAIAWLLRGSGYIYCDPMEACDIYTRQCST 202
Query 195 LVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAAGDWLTTVGIPA 254
LVT DL MG+ LANGG + TGKR++ R V VL+ M G+Y +GDW TVG+PA
Sbjct 203 LVTTADLAVMGATLANGGTNPITGKRVIARKNVPHVLAEMTMEGVYTRSGDWAYTVGLPA 262
Query 255 KSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGLHL 303
KSGV GG++ V PGQ++IAAFSP LD+ GNSVR + +++ + L L
Sbjct 263 KSGVGGGLVAVAPGQLAIAAFSPPLDKVGNSVRAQAAVAQIADTLQLGL 311
>P77454 Glutaminase 1 [Escherichia coli (strain K12)]
Length=310
Score = 219 bits (558), Expect = 1e-71
Identities = 116/287 (40%), Positives = 175/287 (61%), Gaps = 2/287 (1%)
Query 22 GKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSKPFTYAYVLQQLGLD 81
G+ ADYIP LA+ A+A+ T DG +Y+ GD D F ++S+SK T A L+ +G
Sbjct 24 GQNADYIPFLANVPGQLAAVAIVTCDGNVYSAGDSDYRFALESISKVCTLALALEDVGPQ 83
Query 82 EVLDKVGVEPSGEAFNEISLG--HDKRPKNPMINSGAITTHSLIPIKDQLESAEIIRRFM 139
V DK+G +P+G FN + H +P +P++N+GAI T SLI ++ + + I
Sbjct 84 AVQDKIGADPTGLPFNSVIALELHGGKPLSPLVNAGAIATTSLINAENVEQRWQRILHIQ 143
Query 140 SELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDPVDIVNGYIRQCSILVTVK 199
+LAG ++ + V SE T + N +I ++L + G L D ++ + Y RQCS L+
Sbjct 144 QQLAGEQVALSDEVNQSEQTTNFHNRAIAWLLYSAGYLYCDAMEACDVYTRQCSTLLNTI 203
Query 200 DLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAAGDWLTTVGIPAKSGVA 259
+L +G+ LA GG++ T KR+L D V +L+ MM G+Y +GDW VG+P KSGV
Sbjct 204 ELATLGATLAAGGVNPLTHKRVLQADNVPYILAEMMMEGLYGRSGDWAYRVGLPGKSGVG 263
Query 260 GGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGLHLMEG 306
GGIL V+PG + IAAFSP LDE GNSVRG +M+ +++ +G ++ +G
Sbjct 264 GGILAVVPGVMGIAAFSPPLDEDGNSVRGQKMVASVAKQLGYNVFKG 310
>P13264 Glutaminase kidney isoform, mitochondrial [Rattus norvegicus]
Length=674
Score = 218 bits (556), Expect = 1e-67
Identities = 122/292 (42%), Positives = 177/292 (61%), Gaps = 4/292 (1%)
Query 8 YLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSK 67
++ + + + GK+ADYIP+LA +PD +++ TVDGQ +++GD + F +QS K
Sbjct 235 HIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVK 294
Query 68 PFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTHSLIPIK- 126
P YA + LG + V VG EPSG FN++ L D +P NPM+N+GAI SLI
Sbjct 295 PLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGV 354
Query 127 DQLESAEIIRRFMSELAGRELC-FDEAVYASEIKTAYRNLSIGYMLRTVGILE--TDPVD 183
+ E + + +F++++AG E F A + SE ++ RN +IGY L+ TD V
Sbjct 355 NNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVG 414
Query 184 IVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAA 243
I++ Y + CSI VT + M + LANGG TG+R+L+ + VR LS+M SCGMYD +
Sbjct 415 ILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFS 474
Query 244 GDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERL 295
G + VG+PAKSGVAGGIL V+P + + +SP LD+ GNSV+GI L
Sbjct 475 GQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDL 526
>D3Z7P3 Glutaminase kidney isoform, mitochondrial [Mus musculus]
Length=674
Score = 218 bits (556), Expect = 1e-67
Identities = 122/292 (42%), Positives = 177/292 (61%), Gaps = 4/292 (1%)
Query 8 YLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSK 67
++ + + + GK+ADYIP+LA +PD +++ TVDGQ +++GD + F +QS K
Sbjct 235 HIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVK 294
Query 68 PFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTHSLIPIK- 126
P YA + LG + V VG EPSG FN++ L D +P NPM+N+GAI SLI
Sbjct 295 PLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGV 354
Query 127 DQLESAEIIRRFMSELAGRELC-FDEAVYASEIKTAYRNLSIGYMLRTVGILE--TDPVD 183
+ E + + +F++++AG E F A + SE ++ RN +IGY L+ TD V
Sbjct 355 NNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVG 414
Query 184 IVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAA 243
I++ Y + CSI VT + M + LANGG TG+R+L+ + VR LS+M SCGMYD +
Sbjct 415 ILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFS 474
Query 244 GDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERL 295
G + VG+PAKSGVAGGIL V+P + + +SP LD+ GNSV+GI L
Sbjct 475 GQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDL 526
>O94925 Glutaminase kidney isoform, mitochondrial [Homo sapiens]
Length=669
Score = 217 bits (553), Expect = 3e-67
Identities = 122/292 (42%), Positives = 176/292 (60%), Gaps = 4/292 (1%)
Query 8 YLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSK 67
++ + + + GK+ADYIP+LA +PD +++ TVDGQ ++ GD + F +QS K
Sbjct 230 HIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSTGDTKVPFCLQSCVK 289
Query 68 PFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTHSLIPIK- 126
P YA + LG + V VG EPSG FN++ L D +P NPM+N+GAI SLI
Sbjct 290 PLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGV 349
Query 127 DQLESAEIIRRFMSELAGRELC-FDEAVYASEIKTAYRNLSIGYMLRTVGILE--TDPVD 183
+ E + + +F++++AG E F A + SE ++ RN +IGY L+ TD V
Sbjct 350 NNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVG 409
Query 184 IVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAA 243
I++ Y + CSI VT + M + LANGG TG+R+L+ + VR LS+M SCGMYD +
Sbjct 410 ILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFS 469
Query 244 GDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERL 295
G + VG+PAKSGVAGGIL V+P + + +SP LD+ GNSV+GI L
Sbjct 470 GQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDL 521
>Q571F8 Glutaminase liver isoform, mitochondrial [Mus musculus]
Length=602
Score = 206 bits (525), Expect = 1e-63
Identities = 121/303 (40%), Positives = 177/303 (58%), Gaps = 7/303 (2%)
Query 7 EYLAHV---IDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQ 63
E+ HV + + GK+A YIP LA +NPD +++ TVDGQ ++VG I F +Q
Sbjct 159 EFTGHVDRIFEDAKEPTGGKVAAYIPHLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQ 218
Query 64 SMSKPFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTHSLI 123
S KP TYA + LG D V VG EPSG +N++SL + P NPM+N+GAI SLI
Sbjct 219 SCVKPLTYAISVSTLGTDYVHKFVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLI 278
Query 124 PIK-DQLESAEIIRRFMSELAGRE-LCFDEAVYASEIKTAYRNLSIGYMLRTVGILE--T 179
+ ++ E + + ++++++AG E + F A + SE +T RN +IGY L+
Sbjct 279 KMDCNKAEKFDFVLQYLNKMAGNEFMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGV 338
Query 180 DPVDIVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGM 239
D + ++ Y + CS+ VT + M + LANGGI TG+ +L+ + VR LS+M SCGM
Sbjct 339 DMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGM 398
Query 240 YDAAGDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDM 299
YD +G + VG+PAKS V+G IL V+P + + SP LD+ GNS RGI ++L
Sbjct 399 YDFSGQFAFHVGLPAKSAVSGAILLVVPNVMGMMCLSPPLDKLGNSQRGINFCQKLVSLF 458
Query 300 GLH 302
H
Sbjct 459 NFH 461
>P28492 Glutaminase liver isoform, mitochondrial [Rattus norvegicus]
Length=602
Score = 206 bits (523), Expect = 2e-63
Identities = 121/303 (40%), Positives = 177/303 (58%), Gaps = 7/303 (2%)
Query 7 EYLAHV---IDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQ 63
E+ HV + + GK+A YIP LA +NPD +++ TVDGQ ++VG I F +Q
Sbjct 159 EFTGHVDRIFEDAKELTGGKVAAYIPHLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQ 218
Query 64 SMSKPFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTHSLI 123
S KP TYA + LG D V VG EPSG +N++SL + P NPM+N+GAI SLI
Sbjct 219 SCVKPLTYAISVSTLGTDYVHKFVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLI 278
Query 124 PIK-DQLESAEIIRRFMSELAGRE-LCFDEAVYASEIKTAYRNLSIGYMLRTVGILE--T 179
+ ++ E + + ++++++AG E + F A + SE +T RN +IGY L+
Sbjct 279 KMDCNKAEKFDFVLQYLNKMAGNEFMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGV 338
Query 180 DPVDIVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGM 239
D + ++ Y + CS+ VT + M + LANGGI TG+ +L+ + VR LS+M SCGM
Sbjct 339 DMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGM 398
Query 240 YDAAGDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDM 299
YD +G + VG+PAKS V+G IL V+P + + SP LD+ GNS RGI ++L
Sbjct 399 YDFSGQFAFHVGLPAKSAVSGAILLVVPNVMGMMCLSPPLDKLGNSHRGISFCQKLVSLF 458
Query 300 GLH 302
H
Sbjct 459 NFH 461
Score = 18.5 bits (36), Expect = 9.5
Identities = 28/140 (20%), Positives = 49/140 (35%), Gaps = 30/140 (21%)
Query 74 VLQQLGLDEVLDKVGVEPSGEAF-----------NEISLGHDKRPKNPMINSGAITTHSL 122
V+ + L LDK+G G +F N +L H R +P G + ++
Sbjct 428 VMGMMCLSPPLDKLGNSHRGISFCQKLVSLFNFHNYDNLRHCARKLDPRREGGEVRNKTV 487
Query 123 IPIKDQLESAEI--IRRFMSELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETD 180
+ + S ++ +RRF E ++ A + A +
Sbjct 488 VNLLFAAYSGDVSALRRFALSAVDMEQKDYDSRTALHVAAAEGH---------------- 531
Query 181 PVDIVNGYIRQCSILVTVKD 200
+D+V I C + VKD
Sbjct 532 -IDVVKFLIEACKVNPFVKD 550
>Q9UI32 Glutaminase liver isoform, mitochondrial [Homo sapiens]
Length=602
Score = 204 bits (520), Expect = 6e-63
Identities = 120/303 (40%), Positives = 177/303 (58%), Gaps = 7/303 (2%)
Query 7 EYLAHV---IDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQ 63
E+ HV + + GK+A YIP+LA +NPD +++ TVDGQ ++VG I F +Q
Sbjct 159 EFTGHVDRIFEDVKELTGGKVAAYIPQLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQ 218
Query 64 SMSKPFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTHSLI 123
S KP TYA + LG D V VG EPSG +N++SL + P NPM+N+GAI SLI
Sbjct 219 SCVKPLTYAISISTLGTDYVHKFVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLI 278
Query 124 PIK-DQLESAEIIRRFMSELAGRE-LCFDEAVYASEIKTAYRNLSIGYMLRTVGILE--T 179
+ ++ E + + ++++++AG E + F A + SE +T RN +IGY L+
Sbjct 279 KMDCNKAEKFDFVLQYLNKMAGNEYMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGV 338
Query 180 DPVDIVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGM 239
D + ++ Y + CS+ VT + M + LANGGI TG+ +L+ + VR LS+M SCGM
Sbjct 339 DMMAALDLYFQLCSVEVTCESGSVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGM 398
Query 240 YDAAGDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDM 299
YD +G + VG+PAKS V+G IL V+P + + SP LD+ GNS RG ++L
Sbjct 399 YDFSGQFAFHVGLPAKSAVSGAILLVVPNVMGMMCLSPPLDKLGNSHRGTSFCQKLVSLF 458
Query 300 GLH 302
H
Sbjct 459 NFH 461
>O07637 Glutaminase 2 [Bacillus subtilis (strain 168)]
Length=309
Score = 192 bits (488), Expect = 3e-61
Identities = 105/279 (38%), Positives = 168/279 (60%), Gaps = 4/279 (1%)
Query 22 GKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSKPFTYAYVLQQLGLD 81
G++A YIP LA A+ +++A+ + + GD + FT+QS+SK + A VL + G D
Sbjct 23 GEVASYIPALAKADKHDLSVAIYYSNNVCLSAGDVEKTFTLQSISKVLSLALVLMEYGKD 82
Query 82 EVLDKVGVEPSGEAFNEI---SLGHDKRPKNPMINSGAITTHSLIPIKDQLESAEIIRRF 138
+V VG EP+G+ FN I + +P NPMIN+GA+ SLI + E + + F
Sbjct 83 KVFSYVGQEPTGDPFNSIIKLETVNPSKPLNPMINAGALVVTSLIRGRTVKERLDYLLSF 142
Query 139 MSELAG-RELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDPVDIVNGYIRQCSILVT 197
+ L +E+ + V SE T+ N ++ Y ++ GI E D +++ Y +QC+I +
Sbjct 143 IRRLTNNQEITYCREVAESEYSTSMINRAMCYYMKQYGIFEDDVEAVMDLYTKQCAIEMN 202
Query 198 VKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAAGDWLTTVGIPAKSG 257
DL K+GS+ A G TG++++++DV R + M++CGMY+A+G++ VGIPAKSG
Sbjct 203 SLDLAKIGSVFALNGRHPETGEQVISKDVARICKTFMVTCGMYNASGEFAIKVGIPAKSG 262
Query 258 VAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLS 296
V+GGI+G+ P I F P LDE GNS+ G++++E +S
Sbjct 263 VSGGIMGISPYDFGIGIFGPALDEKGNSIAGVKLLEIMS 301
>O31465 Glutaminase 1 [Bacillus subtilis (strain 168)]
Length=327
Score = 191 bits (486), Expect = 1e-60
Identities = 99/295 (34%), Positives = 171/295 (58%), Gaps = 13/295 (4%)
Query 22 GKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSKPFTYAYVLQQLGLD 81
G+ A+YIP L N Q+ + + DG + GD ++ FT+QS+SK ++ G+
Sbjct 32 GQSANYIPALGKVNDSQLGICVLEPDGTMIHAGDWNVSFTMQSISKVISFIAACMSRGIP 91
Query 82 EVLDKVGVEPSGEAFNEI---SLGHDKRPKNPMINSGAITTHSLIPIKDQLESAEIIRRF 138
VLD+V VEP+G+AFN I + +P NPMIN+GA+T S++P + E E +
Sbjct 92 YVLDRVDVEPTGDAFNSIIRLEINKPGKPFNPMINAGALTIASILPGESAYEKLEFLYSV 151
Query 139 MSELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDPVDIVNGYIRQCSILVTV 198
M L G+ E V+ SE +TA+RN ++ Y L+ LE + + + Y++QC++ T
Sbjct 152 METLIGKRPRIHEEVFRSEWETAHRNRALAYYLKETNFLEAEVEETLEVYLKQCAMESTT 211
Query 199 KDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAAGDWLTTVGIPAKSGV 258
+D+ +G ILA+ G ++++ +DV + ++M++CGMY+A+G + VG+PAKSGV
Sbjct 212 EDIALIGLILAHDGYHPIRHEQVIPKDVAKLAKALMLTCGMYNASGKYAAFVGVPAKSGV 271
Query 259 AGGILGVLPGQV----------SIAAFSPRLDEHGNSVRGIEMMERLSRDMGLHL 303
+GGI+ ++P I + P +DE+GNS+ G +++ ++++ L +
Sbjct 272 SGGIMALVPPSARREQPFQSGCGIGIYGPAIDEYGNSLTGGMLLKHMAQEWELSI 326
>O87405 Thermolabile glutaminase [Rhizobium etli (strain CFN 42
/ ATCC 51251)]
Length=309
Score = 190 bits (483), Expect = 2e-60
Identities = 117/284 (41%), Positives = 170/284 (60%), Gaps = 7/284 (2%)
Query 22 GKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSKPFTYAYVLQQLGLD 81
GK+ADYIPELA +P Q +A+ TVDGQ++ VGD DI F+IQS+SK F L ++G +
Sbjct 22 GKVADYIPELAKIDPRQFGMAIVTVDGQVFRVGDADIAFSIQSISKVFMLTLALGKVG-E 80
Query 82 EVLDKVGVEPSGEAFNEI-SLGHDKR-PKNPMINSGAITTHSLIPIKDQ-LESAEIIRRF 138
+ +VG EPSG AFN I L H+ P+NP IN+GAI ++ E+ + RF
Sbjct 81 GLWKRVGREPSGSAFNSIVQLEHESGIPRNPFINAGAIAVTDVVMAGHAPREAIGELLRF 140
Query 139 MSELAGRE-LCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDPVDIVNG-YIRQCSILV 196
+ LA E + D+ V SE +T YRN+++ +R L+ PVD V G Y QC++ +
Sbjct 141 VRYLADDESITIDDKVARSETQTGYRNVALANFMRAYRNLD-HPVDHVLGVYFHQCALAM 199
Query 197 TVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAAGDWLTTVGIPAKS 256
+ + L + G LA G + TG +++ R++ ++M++CG YD +GD+ VG+P KS
Sbjct 200 SCEQLARAGLFLAARGSNPMTGHSVVSPKRARRINALMLTCGHYDGSGDFAYHVGLPGKS 259
Query 257 GVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMG 300
GV GGI V PG SIA +SP L++ GNS G +E L+ G
Sbjct 260 GVGGGIFAVAPGIASIAVWSPGLNKVGNSQLGAVALEMLAARTG 303
>P0A6W0 Glutaminase 2 [Escherichia coli (strain K12)]
Length=308
Score = 169 bits (429), Expect = 2e-52
Identities = 88/281 (31%), Positives = 160/281 (57%), Gaps = 2/281 (1%)
Query 22 GKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSKPFTYAYVLQQLGLD 81
GK+ADYIP LA + ++ +A+ TVDGQ++ GD F+IQS+SK + ++ +
Sbjct 24 GKVADYIPALATVDGSRLGIAICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHYSEE 83
Query 82 EVLDKVGVEPSGEAFNEISLGHDKR--PKNPMINSGAITTHSLIPIKDQLESAEIIRRFM 139
E+ +VG +PSG FN + ++ P+NP IN+GA+ ++ + ++
Sbjct 84 EIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVR 143
Query 140 SELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETDPVDIVNGYIRQCSILVTVK 199
++ +D V SE + + RN +I +++++ G D ++ Y C++ ++
Sbjct 144 GLSGVSDISYDTVVARSEFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCV 203
Query 200 DLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMYDAAGDWLTTVGIPAKSGVA 259
+L + LAN G + ++ RQ+ ++M + GMY AG++ VG+PAKSGV
Sbjct 204 ELARTFVFLANQGKAIHIDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVG 263
Query 260 GGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMG 300
GGI+ ++P +++IA +SP LD+ GNS+ GI ++E+L++ +G
Sbjct 264 GGIVAIVPHEMAIAVWSPELDDAGNSLAGIAVLEQLTKQLG 304
Lambda K H a alpha
0.320 0.137 0.389 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 3160854
Database: da854e4ef87c86c17f0670d940c87e58.SwissProt.fasta
Posted date: Jun 3, 2024 2:58 PM
Number of letters in database: 9,732
Number of sequences in database: 22
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
