BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 2508862f526b703f058c8f1750b5f34d.SwissProt.fasta
17 sequences; 5,601 total letters
Query= ACIAD1121
Length=324
Score E
Sequences producing significant alignments: (Bits) Value
Q02104 Lipase 1 [Psychrobacter immobilis] 160 5e-50
P24640 Lipase 3 [Moraxella sp. (strain TA144)] 155 2e-48
Q9BV23 Monoacylglycerol lipase ABHD6 [Homo sapiens] 104 5e-29
Q1LZ86 Monoacylglycerol lipase ABHD6 [Bos taurus] 103 9e-29
Q7SY73 Monoacylglycerol lipase abhd6-B [Xenopus laevis] 103 1e-28
Q8R2Y0 Monoacylglycerol lipase ABHD6 [Mus musculus] 103 2e-28
Q5XI64 Monoacylglycerol lipase ABHD6 [Rattus norvegicus] 102 4e-28
Q6GLL2 Monoacylglycerol lipase abhd6-A [Xenopus laevis] 100 1e-27
Q59695 Dihydrolipoyllysine-residue acetyltransferase component of... 73.6 6e-18
P0A573 Uncharacterized protein Mb2734 [Mycobacterium bovis (strai... 72.8 9e-18
P9WNH3 Uncharacterized protein Rv2715 [Mycobacterium tuberculosis... 72.8 9e-18
P9WNH2 Uncharacterized protein MT2788 [Mycobacterium tuberculosis... 72.8 9e-18
G5EBI4 Epoxide hydrolase 1 [Caenorhabditis elegans] 57.4 2e-12
Q52532 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedi... 54.3 1e-11
Q52036 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase [Pseud... 53.5 2e-11
Q8NFV4 sn-1-specific diacylglycerol lipase ABHD11 [Homo sapiens] 51.6 9e-11
Q83WC8 Bifunctional esterase/perhydrolase DCH [Acinetobacter calc... 50.8 1e-10
>Q02104 Lipase 1 [Psychrobacter immobilis]
Length=317
Score = 160 bits (404), Expect = 5e-50
Identities = 95/285 (33%), Positives = 155/285 (54%), Gaps = 10/285 (4%)
Query 37 QNVLQQERAWAGLQTKHLKV--GDIEWVYSESGNSSKPTIILIHGLAGSRDNWNRVAYNL 94
Q ++Q ER + L+ K L + GD + VY+E+GN + ++LIHG G++DN+ R+A L
Sbjct 32 QKIIQYERNKSDLEIKSLTLASGD-KMVYAENGNVAGEPLLLIHGFGGNKDNFTRIARQL 90
Query 95 TPYYHVIIPDLPAHGDTKIPNDFDLSIPNLTEKLRRFAEAGHFEKNVHIAGHSMGGAIAL 154
Y H+IIPDL G++ P D +L +A N+H+ G+SMGGAI++
Sbjct 91 EGY-HLIIPDLLGFGESSKPMSADYRSEAQRTRLHELLQAKGLASNIHVGGNSMGGAISV 149
Query 155 LYTAQYPLETKSLLLVDSAGVFKTANTPYLKDPNLLNN-LVVKKTGDFDKLFKLATASPP 213
Y A+YP + KSL LVDSAG + L+ L NN L++K DF K++ PP
Sbjct 150 AYAAKYPKDVKSLWLVDSAGFWSAGIPKSLEGATLENNPLLIKSNEDFYKMYDFVMYKPP 209
Query 214 FIPVELKTEQEKLMIAQSKNTQKMVDQLVAMSKIYTPDTFAIATKSIDVPTYIIWGDQDK 273
++P +K + I + K+++Q+V + + A +PT ++WGD+D+
Sbjct 210 YLPKSVKAVFAQERIKNKELDAKILEQIVTDN----VEERAKIIAQYKIPTLVVWGDKDQ 265
Query 274 IINVEAAQELKSLLKNAETPYILKGVGHMPILEADQLVSQQYLIF 318
II E +K ++ A+ +++ VGH+P++EA + Y F
Sbjct 266 IIKPETVNLIKKIIPQAQV-IMMEDVGHVPMVEALDETADNYKAF 309
>P24640 Lipase 3 [Moraxella sp. (strain TA144)]
Length=315
Score = 155 bits (393), Expect = 2e-48
Identities = 95/287 (33%), Positives = 156/287 (54%), Gaps = 14/287 (5%)
Query 37 QNVLQQERAWAGLQTKHLKV--GDIEWVYSESGNSSKPTIILIHGLAGSRDNWNRVAYNL 94
Q ++Q ER+ + L+ K L + GD + VY+E+ N + ++LIHG G++DN+ R+A L
Sbjct 32 QKIIQYERSKSDLEVKSLTLASGD-KMVYAENDNVTGEPLLLIHGFGGNKDNFTRIADKL 90
Query 95 TPYYHVIIPDLPAHGDTKIPNDFDLSIPNLTEKLRRFAEAGHFEKNVHIAGHSMGGAIAL 154
Y H+IIPDL G++ P D +L +A N H+ G+SMGGAI++
Sbjct 91 EGY-HLIIPDLLGFGNSSKPMTADYRADAQATRLHELMQAKGLASNTHVGGNSMGGAISV 149
Query 155 LYTAQYPLETKSLLLVDSAGVFKTANTPYLKDPNLLNN-LVVKKTGDFDKLFKLATASPP 213
Y A+YP E KSL LVD+AG + L+ L NN L++ DF K++ PP
Sbjct 150 AYAAKYPKEIKSLWLVDTAGFWSAGVPKSLEGATLENNPLLINSKEDFYKMYDFVMYKPP 209
Query 214 FIPVELKTEQEKLMIAQSKNTQKMVDQLVAMSKIYTP--DTFAIATKSIDVPTYIIWGDQ 271
+IP +K + AQ + K +D + + +I T + A ++PT ++WGD+
Sbjct 210 YIPKSVKA-----VFAQERINNKALDTKI-LEQIVTDNVEERAKIIAKYNIPTLVVWGDK 263
Query 272 DKIINVEAAQELKSLLKNAETPYILKGVGHMPILEADQLVSQQYLIF 318
D++I E + +K ++ A+ ++ VGH+P++EA + + Y F
Sbjct 264 DQVIKPETTELIKEIIPQAQV-IMMNDVGHVPMVEAVKDTANDYKAF 309
>Q9BV23 Monoacylglycerol lipase ABHD6 [Homo sapiens]
Length=337
Score = 104 bits (260), Expect = 5e-29
Identities = 76/286 (27%), Positives = 135/286 (47%), Gaps = 14/286 (5%)
Query 44 RAWAGLQTKHLKVGDIEWVYSESGNSS-KPTIILIHGLAGSRDNWNRVAYNLTPYYHVII 102
R G+Q +++ D ++ YS G KP+I+++HG + +D W V L H++
Sbjct 43 RRTLGMQVRYVHHEDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVC 102
Query 103 PDLPAHGDTKIPNDFDLSIPNLTEKLRRFAEAGHFEKN-VHIAGHSMGGAIALLYTAQYP 161
D+P H T + DLSI +++ +F E K H+ G SMGG +A +Y A YP
Sbjct 103 VDMPGHEGTTRSSLDDLSIDGQVKRIHQFVECLKLNKKPFHLVGTSMGGQVAGVYAAYYP 162
Query 162 LETKSLLLVDSAGV-FKTANTPYLKDPNLLNNLVVKK-------TGDFDKLFKLATASPP 213
+ SL LV AG+ + T N + L + V+K + ++ +L +
Sbjct 163 SDVSSLCLVCPAGLQYSTDNQFVQRLKELQGSAAVEKIPLIPSTPEEMSEMLQLCSYVRF 222
Query 214 FIPVELKTEQEKLMIAQSKNTQKMVDQLVAMSKIYTPDTFAIATKSIDVPTYIIWGDQDK 273
+P ++ + I + +K+ ++V+ Y + I VPT IIWG QD+
Sbjct 223 KVPQQILQGLVDVRIPHNNFYRKLFLEIVSEKSRY---SLHQNMDKIKVPTQIIWGKQDQ 279
Query 274 IINVEAAQELKSLLKNAETPYILKGVGHMPILEADQLVSQQYLIFL 319
+++V A L + N + +L+ GH ++E + ++ + FL
Sbjct 280 VLDVSGADMLAKSIANCQVE-LLENCGHSVVMERPRKTAKLIIDFL 324
>Q1LZ86 Monoacylglycerol lipase ABHD6 [Bos taurus]
Length=337
Score = 103 bits (258), Expect = 9e-29
Identities = 80/297 (27%), Positives = 133/297 (45%), Gaps = 36/297 (12%)
Query 44 RAWAGLQTKHLKVGDIEWVYSESGNSS-KPTIILIHGLAGSRDNWNRVAYNLTPYYHVII 102
R G+Q ++++ D ++ YS G KP+I+++HG + +D W + L H++
Sbjct 43 RRTLGMQVRYVRHEDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSMVKFLPKNLHLVC 102
Query 103 PDLPAHGDTKIPNDFDLSIPNLTEKLRRFAEAGHFEKN-VHIAGHSMGGAIALLYTAQYP 161
D+P H T + DLSI +++ +F E K H+ G SMGG +A +Y A YP
Sbjct 103 VDMPGHEGTTRSSLDDLSIDGQVKRIHQFVECLKLNKKPFHLVGTSMGGHVAGVYAAHYP 162
Query 162 LETKSLLLVDSAGV-FKTANTPYLKDPNLLNNLVVKKTGDFDKLFKLATASPPFIPVELK 220
+ SL LV AG+ + T N + L + V+K P IP K
Sbjct 163 SDVCSLSLVCPAGLQYSTDNKFVQRLKELQESAAVEKI--------------PLIPTTPK 208
Query 221 TEQEKLMIAQ-------SKNTQKMVDQLVAMSKIYTPDTFAIATK-----------SIDV 262
E L + + Q +VD + + Y I ++ I V
Sbjct 209 EMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNTFYRKLFLEIVSEKSRYSLHQNMDKIKV 268
Query 263 PTYIIWGDQDKIINVEAAQELKSLLKNAETPYILKGVGHMPILEADQLVSQQYLIFL 319
PT IIWG QD++++V A L + N++ +L+ GH ++E + ++ + FL
Sbjct 269 PTQIIWGKQDQVLDVSGADMLAKSIANSQVE-LLENCGHSVVMERPRKTAKLLVDFL 324
>Q7SY73 Monoacylglycerol lipase abhd6-B [Xenopus laevis]
Length=337
Score = 103 bits (257), Expect = 1e-28
Identities = 75/294 (26%), Positives = 141/294 (48%), Gaps = 36/294 (12%)
Query 48 GLQTKHLKVGDIEWVYSESGN-SSKPTIILIHGLAGSRDNWNRVAYNLTPYYHVIIPDLP 106
G+Q K+ G+ ++ Y+ G +KP+++++HG + +D W + L H++ D+P
Sbjct 47 GMQVKYSSYGNYKFCYTARGKPGNKPSVLMLHGFSAHKDMWLGMVKFLPKNLHLVCVDMP 106
Query 107 AH-GDTKIPNDFDLSIPNLTEKLRRFAEA-GHFEKNVHIAGHSMGGAIALLYTAQYPLET 164
H G ++ D+ SI +++ +F E+ G +K H+ G SMGG +A +Y AQ+P
Sbjct 107 GHEGTSRSALDY-YSICGQVKRIHQFVESIGLNKKPFHLVGTSMGGNVAGVYAAQHPTHI 165
Query 165 KSLLLVDSAGVFKTANTPYLKDPNLLNNLVVKKTGDFDKLFKLATASPPFIPVELKTEQE 224
SL L+ AG+ + +LK V++K+GD ++ P IP ++
Sbjct 166 SSLTLICPAGLMYPIESKFLKQLK-----VLEKSGDNQRI--------PLIPSTAGEMED 212
Query 225 KLMIAQ-------SKNTQKMVDQLVAMSKIYTPDTFAIATK-----------SIDVPTYI 266
L + + Q ++D+ + ++ Y A+ + I PT I
Sbjct 213 MLRLCSFVRFKIPQQVLQGLIDERIPHNEFYRKLFLALVDEKSRHSLHENMNKIMAPTQI 272
Query 267 IWGDQDKIINVEAAQELKSLLKNAETPYILKGVGHMPILEADQLVSQQYLIFLN 320
IWG QD++++V A+ L L+ + IL+ GH ++E + ++ FL+
Sbjct 273 IWGKQDQVLDVSGAEVLAGSLRGCQVE-ILENCGHSVVMERPRKSAKLMTDFLS 325
>Q8R2Y0 Monoacylglycerol lipase ABHD6 [Mus musculus]
Length=336
Score = 103 bits (256), Expect = 2e-28
Identities = 74/286 (26%), Positives = 134/286 (47%), Gaps = 14/286 (5%)
Query 44 RAWAGLQTKHLKVGDIEWVYSESGNSS-KPTIILIHGLAGSRDNWNRVAYNLTPYYHVII 102
R G+Q ++ D ++ YS G KP+I+++HG + +D W V L H++
Sbjct 43 RRTLGMQVRYAHHEDYQFCYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVC 102
Query 103 PDLPAHGDTKIPNDFDLSIPNLTEKLRRFAEAGHFEKN-VHIAGHSMGGAIALLYTAQYP 161
D+P H T + DLSI +++ +F E K H+ G SMGG +A +Y A YP
Sbjct 103 VDMPGHEGTTRSSLDDLSIVGQVKRIHQFVECLKLNKKPFHLIGTSMGGHVAGVYAAYYP 162
Query 162 LETKSLLLVDSAGVFKTANTPYLKDPNLLNN--------LVVKKTGDFDKLFKLATASPP 213
+ SL LV AG+ + + P+++ L L+ + ++ +L +
Sbjct 163 SDVCSLSLVCPAGLQYSTDNPFVQRLKELEESAAIQKIPLIPSTPEEMSEMLQLCSYVRF 222
Query 214 FIPVELKTEQEKLMIAQSKNTQKMVDQLVAMSKIYTPDTFAIATKSIDVPTYIIWGDQDK 273
+P ++ + I + +K+ ++V Y + I VPT IIWG QD+
Sbjct 223 KVPQQILQGLVDVRIPHNSFYRKLFLEIVNEKSRY---SLHENMDKIKVPTQIIWGKQDQ 279
Query 274 IINVEAAQELKSLLKNAETPYILKGVGHMPILEADQLVSQQYLIFL 319
+++V A L + N++ +L+ GH ++E + ++ + FL
Sbjct 280 VLDVSGADILAKSISNSQVE-VLENCGHSVVMERPRKTAKLIVDFL 324
>Q5XI64 Monoacylglycerol lipase ABHD6 [Rattus norvegicus]
Length=337
Score = 102 bits (253), Expect = 4e-28
Identities = 81/296 (27%), Positives = 132/296 (45%), Gaps = 34/296 (11%)
Query 44 RAWAGLQTKHLKVGDIEWVYSESGNSS-KPTIILIHGLAGSRDNWNRVAYNLTPYYHVII 102
R G+Q +++ D ++ YS G KP+++++HG + +D W V L H++
Sbjct 43 RRTLGMQVRYVHHEDYQFCYSFRGRPGHKPSVLMLHGFSAHKDMWLSVVKFLPKNLHLVC 102
Query 103 PDLPAHGDTKIPNDFDLSIPNLTEKLRRFAEAGHFEKN-VHIAGHSMGGAIALLYTAQYP 161
D+P H T + DLSI +++ +F E K H+ G SMGG +A +Y A YP
Sbjct 103 VDMPGHEGTTRSSLDDLSIVGQVKRIHQFVECLKLNKKPFHLIGTSMGGNVAGVYAAYYP 162
Query 162 LETKSLLLVDSAGVFKTANTPYLKDPNLLNNLVVKKTGDFDKLFKLATASPPFIPVELKT 221
+ SL LV AG+ Y D + L K+ D AT P IP +
Sbjct 163 SDVCSLSLVCPAGL------QYSTDNRFVQRL--KELED-----SAATQKIPLIPSTPEE 209
Query 222 EQEKLMIAQ-------SKNTQKMVDQLVAMSKIYTPDTFAIATK-----------SIDVP 263
E L + + Q +VD + + Y I ++ I VP
Sbjct 210 MSEMLQLCSYVRFKVPQQILQGLVDVRIPHNSFYRKLFLEIVSEKSRYSLHENMDKIKVP 269
Query 264 TYIIWGDQDKIINVEAAQELKSLLKNAETPYILKGVGHMPILEADQLVSQQYLIFL 319
T IIWG QD++++V A L + N++ +L+ GH ++E + ++ + FL
Sbjct 270 TQIIWGKQDQVLDVSGADILAKSITNSQVE-VLENCGHSVVMERPRKTAKLVVDFL 324
>Q6GLL2 Monoacylglycerol lipase abhd6-A [Xenopus laevis]
Length=337
Score = 100 bits (250), Expect = 1e-27
Identities = 75/296 (25%), Positives = 136/296 (46%), Gaps = 40/296 (14%)
Query 48 GLQTKHLKVGDIEWVYSESGN-SSKPTIILIHGLAGSRDNWNRVAYNLTPYYHVIIPDLP 106
G+Q K G+ ++ Y+ G +K +++++HG + +D W V L H++ D+P
Sbjct 47 GMQVKFSSYGNYKFCYTSRGKPGNKASVLMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMP 106
Query 107 AHGDTKIPNDFDLSIPNLTEKLRRFAEA-GHFEKNVHIAGHSMGGAIALLYTAQYPLETK 165
H T D SI +++ +F E+ G ++ H+ G SMGG +A +Y AQ+P +
Sbjct 107 GHEGTTRSALDDYSICGQVKRIHQFVESIGLNKRTFHLVGTSMGGNVAGVYAAQHPTDIS 166
Query 166 SLLLVDSAGVFKTANTPYLK----------DPNLLNNLVVKKTGDFDKLFKLATASPPFI 215
SL L+ AG+ + +LK D +L L+ G+ + + +L +
Sbjct 167 SLTLICPAGLMYPTESKFLKHLKGLEKSGDDQRIL--LIPSTAGEMEDMLRLCSF----- 219
Query 216 PVELKTEQEKLMIAQSKNTQKMVDQLVAMSKIYTPDTFAIATK-----------SIDVPT 264
V K Q+ L Q +VD + ++ Y A+ + I PT
Sbjct 220 -VRFKIPQQVL--------QGLVDVRIPHNEFYRQLFMALVNEKSRHSLQENMNKIVAPT 270
Query 265 YIIWGDQDKIINVEAAQELKSLLKNAETPYILKGVGHMPILEADQLVSQQYLIFLN 320
IIWG QD++++V A+ L ++ + IL+ GH ++E + ++ FL+
Sbjct 271 QIIWGKQDQVLDVSGAEVLAGSIRGCQVE-ILENCGHSVVMERPRKSAKLMTDFLS 325
>Q59695 Dihydrolipoyllysine-residue acetyltransferase component
of acetoin cleaving system [Pseudomonas putida]
Length=370
Score = 73.6 bits (179), Expect = 6e-18
Identities = 73/259 (28%), Positives = 109/259 (42%), Gaps = 18/259 (7%)
Query 65 ESGNSSKPTIILIHGLAGSRDNWNRVAYNLTPYYHVIIPDLPAHGDT-KIPNDFDLSIPN 123
E G ++L+HG G +NW L VI DLP HG++ K DL
Sbjct 127 ELGGEGGTPLVLVHGFGGDLNNWLFNHPALAAERRVIALDLPGHGESAKALQRGDLD--E 184
Query 124 LTEKLRRFAEAGHFEKNVHIAGHSMGGAIALLYTAQYPLETKSLLLVDSAGVFKTANTPY 183
L+E + + K H+AGHSMGGA++L P SL L+ SAG+ + N Y
Sbjct 185 LSETVLALLDHLDIAK-AHLAGHSMGGAVSLNVAGLAPQRVASLSLIASAGLGEAINGQY 243
Query 184 LKDPNLLNNLVVKKTGDFDKLFKLATASPPFIPVELKTEQEKLMIAQSKNTQKMVDQLVA 243
L+ N K +LF A P + ++ ++ L + + + + QL
Sbjct 244 LQGFVAAANRNALKP-QMVQLF----ADPALVTRQML--EDMLKFKRLEGVDEALRQLAL 296
Query 244 MSKIYTPDTFAIATKSIDVPTYIIWGDQDKIINVEAAQELKSLLKNAETP-YILKGVGHM 302
+ + P ++WG +D II A+ K E +L GHM
Sbjct 297 AIADGDRQRHDLRSVLGQHPALVVWGGKDAIIPASHAR------KGPEAEVLVLPEAGHM 350
Query 303 PILEADQLVSQQYLIFLNK 321
+EA + V+QQ L FL K
Sbjct 351 VQMEAAEQVNQQMLAFLRK 369
>P0A573 Uncharacterized protein Mb2734 [Mycobacterium bovis (strain
ATCC BAA-935 / AF2122/97)]
Length=341
Score = 72.8 bits (177), Expect = 9e-18
Identities = 66/254 (26%), Positives = 105/254 (41%), Gaps = 32/254 (13%)
Query 70 SKPTIILIHGLAGSRDNWNRVAYNLTPYYHVIIPDLPAHGDTKIPNDFDLSIPNLTEKLR 129
S P I+LIHG+ + WN V L + VI PDL HG + P D S+ +R
Sbjct 36 SGPAILLIHGIGDNSTTWNGVHAKLAQRFTVIAPDLLGHGQSDKPR-ADYSVAAYANGMR 94
Query 130 RFAEAGHFEKNVHIAGHSMGGAIALLYTAQYPLETKSLLLVDSAGVFKTANTPY------ 183
E+ V I GHS+GG +A+ + Q+P L+LV + GV K N +
Sbjct 95 DLLSVLDIER-VTIVGHSLGGGVAMQFAYQFPQLVDRLILVSAGGVTKDVNIVFRLASLP 153
Query 184 --------LKDPNLLNNLVV--KKTGDFDKLFKLATASPPFIPVELKTEQEKLMIAQSKN 233
L+ P +L + + + G L P + + + A +
Sbjct 154 MGSEAMALLRLPLVLPAVQIAGRIVGKAIGTTSLGHDLPNVLRILDDLPEPTASAAFGRT 213
Query 234 TQKMVD---QLVAM-SKIYTPDTFAIATKSIDVPTYIIWGDQDKIINVEAAQELKSLLKN 289
+ +VD Q+V M + Y + +P IIWG +D ++ V A + +
Sbjct 214 LRAVVDWRGQMVTMLDRCYLTEA---------IPVQIIWGTKDVVLPVRHAHMAHAAMPG 264
Query 290 AETPYILKGVGHMP 303
++ I +G GH P
Sbjct 265 SQLE-IFEGSGHFP 277
>P9WNH3 Uncharacterized protein Rv2715 [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=341
Score = 72.8 bits (177), Expect = 9e-18
Identities = 66/254 (26%), Positives = 105/254 (41%), Gaps = 32/254 (13%)
Query 70 SKPTIILIHGLAGSRDNWNRVAYNLTPYYHVIIPDLPAHGDTKIPNDFDLSIPNLTEKLR 129
S P I+LIHG+ + WN V L + VI PDL HG + P D S+ +R
Sbjct 36 SGPAILLIHGIGDNSTTWNGVHAKLAQRFTVIAPDLLGHGQSDKPR-ADYSVAAYANGMR 94
Query 130 RFAEAGHFEKNVHIAGHSMGGAIALLYTAQYPLETKSLLLVDSAGVFKTANTPY------ 183
E+ V I GHS+GG +A+ + Q+P L+LV + GV K N +
Sbjct 95 DLLSVLDIER-VTIVGHSLGGGVAMQFAYQFPQLVDRLILVSAGGVTKDVNIVFRLASLP 153
Query 184 --------LKDPNLLNNLVV--KKTGDFDKLFKLATASPPFIPVELKTEQEKLMIAQSKN 233
L+ P +L + + + G L P + + + A +
Sbjct 154 MGSEAMALLRLPLVLPAVQIAGRIVGKAIGTTSLGHDLPNVLRILDDLPEPTASAAFGRT 213
Query 234 TQKMVD---QLVAM-SKIYTPDTFAIATKSIDVPTYIIWGDQDKIINVEAAQELKSLLKN 289
+ +VD Q+V M + Y + +P IIWG +D ++ V A + +
Sbjct 214 LRAVVDWRGQMVTMLDRCYLTEA---------IPVQIIWGTKDVVLPVRHAHMAHAAMPG 264
Query 290 AETPYILKGVGHMP 303
++ I +G GH P
Sbjct 265 SQLE-IFEGSGHFP 277
>P9WNH2 Uncharacterized protein MT2788 [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=341
Score = 72.8 bits (177), Expect = 9e-18
Identities = 66/254 (26%), Positives = 105/254 (41%), Gaps = 32/254 (13%)
Query 70 SKPTIILIHGLAGSRDNWNRVAYNLTPYYHVIIPDLPAHGDTKIPNDFDLSIPNLTEKLR 129
S P I+LIHG+ + WN V L + VI PDL HG + P D S+ +R
Sbjct 36 SGPAILLIHGIGDNSTTWNGVHAKLAQRFTVIAPDLLGHGQSDKPR-ADYSVAAYANGMR 94
Query 130 RFAEAGHFEKNVHIAGHSMGGAIALLYTAQYPLETKSLLLVDSAGVFKTANTPY------ 183
E+ V I GHS+GG +A+ + Q+P L+LV + GV K N +
Sbjct 95 DLLSVLDIER-VTIVGHSLGGGVAMQFAYQFPQLVDRLILVSAGGVTKDVNIVFRLASLP 153
Query 184 --------LKDPNLLNNLVV--KKTGDFDKLFKLATASPPFIPVELKTEQEKLMIAQSKN 233
L+ P +L + + + G L P + + + A +
Sbjct 154 MGSEAMALLRLPLVLPAVQIAGRIVGKAIGTTSLGHDLPNVLRILDDLPEPTASAAFGRT 213
Query 234 TQKMVD---QLVAM-SKIYTPDTFAIATKSIDVPTYIIWGDQDKIINVEAAQELKSLLKN 289
+ +VD Q+V M + Y + +P IIWG +D ++ V A + +
Sbjct 214 LRAVVDWRGQMVTMLDRCYLTEA---------IPVQIIWGTKDVVLPVRHAHMAHAAMPG 264
Query 290 AETPYILKGVGHMP 303
++ I +G GH P
Sbjct 265 SQLE-IFEGSGHFP 277
>G5EBI4 Epoxide hydrolase 1 [Caenorhabditis elegans]
Length=404
Score = 57.4 bits (137), Expect = 2e-12
Identities = 64/292 (22%), Positives = 117/292 (40%), Gaps = 23/292 (8%)
Query 48 GLQTKHLKVGDIEWVYSESGNSSKPTIILIHGLAGSRDNWNRVAYNLTPYYHVIIPDLPA 107
G ++++K+ + Y ++G+ KP ++ IHG +W Y + D
Sbjct 116 GWDSRYIKLKKVRLHYVQTGSDDKPLMLFIHGYPEFWYSWRFQLKEFADKYRCVAIDQRG 175
Query 108 HGDTKIPNDFD-LSIPNLTEKLRRFAEAGHFEKNVHIAGHSMGGAIALLYTAQYPLETKS 166
+ + P D SI LT +R E ++K + +A H GG +A + QYP
Sbjct 176 YNLSDKPKHVDNYSIDELTGDIRDVIEGLGYDKAIVVA-HDWGGLVAWQFAEQYPEMVDK 234
Query 167 LLL--VDSAGVFK----TANTPYLKDPNLL---NNLVVKKTGDFDKLFKLATASPPFIPV 217
L+ + G F+ T+ + + K + N + + D + L F
Sbjct 235 LICCNIPRPGSFRKRIYTSWSQFRKSWYMFFYQNEKIPEMLCSADDMKMLELC---FRAK 291
Query 218 ELKTEQEKLMIAQSKNTQKMVDQLVAMSKIYTPDTF--------AIATKSIDVPTYIIWG 269
E+ + K + K + S Y + + A +++PT IIWG
Sbjct 292 EIGIQNNKNFTDEDLEAWKYSFSMNGASFKYPINYYRNIFNAKKQQADLVLEMPTLIIWG 351
Query 270 DQDKIINVEAAQELKSLLKNAETPYILKGVGHMPILEADQLVSQQYLIFLNK 321
D +++EAA + + LK T ++G H + ++V++ FLNK
Sbjct 352 TADGALDIEAAVDSLNTLKQG-TMKKIEGASHWVQQDEPEMVNEHIKKFLNK 402
>Q52532 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate
hydrolase [Pseudomonas sp]
Length=283
Score = 54.3 bits (129), Expect = 1e-11
Identities = 59/269 (22%), Positives = 111/269 (41%), Gaps = 27/269 (10%)
Query 64 SESGNSSKPTIILIHGLAGSRDNWNRVAYNLTPY----YHVIIPDLPAHGDTKIPNDFDL 119
+++GN + +++ HG W+ N+ + Y V++ D P F+
Sbjct 27 NDAGNGDE-VVVMFHGSGPGASGWSNFHRNVDAFVDAGYRVLLIDSPG---------FNK 76
Query 120 SIPNLTEKLR-RFAEAGHFE------KNVHIAGHSMGGAIALLYTAQYPLETKSLLLVDS 172
S P +T+ +A+A K H+ G+SMGGA A+ YP L+++
Sbjct 77 SYPIVTKSRDGAYAQAAKGVMDKLGIKRAHMIGNSMGGATAMRMAVDYPEMVGKLVMMGG 136
Query 173 AGVFKTANTPY-LKDPNLLNNLVVKKT-GDFDKLFKLATASPPFIPVELKTEQEKLMIAQ 230
V + TP + LL L + + K+ + +P + EL + + M+ +
Sbjct 137 GSVGGSTTTPMPTEGLKLLQGLYRNPSMENLRKMLDIFVYAPSTLTEELINGRFENMMRR 196
Query 231 SKNTQKMVDQLVAMSKIYTPDTFAIATKSIDVPTYIIWGDQDKIINVEAAQELKSLLKNA 290
++ V+ L A +A ++ +PT IIWG D+ + ++ + + +A
Sbjct 197 PEHLTNFVESLKASG---GRANYAHLLPTLTMPTMIIWGRDDRFVPLDLGLRMLWGMPDA 253
Query 291 ETPYILKGVGHMPILEADQLVSQQYLIFL 319
E ++ GH E +Q L FL
Sbjct 254 EL-HVFSKCGHWAQWEHADKFNQLVLNFL 281
>Q52036 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase [Pseudomonas
putida]
Length=286
Score = 53.5 bits (127), Expect = 2e-11
Identities = 60/262 (23%), Positives = 114/262 (44%), Gaps = 18/262 (7%)
Query 49 LQTKHLKVGDIEWVYSESGNSSKPTIILIHGLAGSRDNWNRVAYNLTPY----YHVIIPD 104
L K + D + Y+E+GN T+I++HG W+ N+ P+ Y VI+ D
Sbjct 13 LNIKEKGLSDFKIHYNEAGNGE--TVIMLHGGGPGAGGWSNYYRNIGPFVEAGYRVILKD 70
Query 105 LPAHGDTK-IPNDFDLSIPNLTEKLRRFAEAGHFEKNVHIAGHSMGGAIALLYTAQYPLE 163
P + + D + N ++ +A ++ H+ G+SMGGA AL + +YP
Sbjct 71 SPGFNKSDAVVMDEQRGLVN-ARAVKGLMDALGIDR-AHLVGNSMGGATALNFAIEYPDR 128
Query 164 TKSLLLVDSAGVFKTANTPY-LKDPNLLNNLVVKKT-GDFDKLFKLATASPPFIPVELKT 221
L+L+ G+ + P L+ LL L + + + ++ ++ I EL
Sbjct 129 IGKLILMGPGGLGPSMFAPMPLEGIKLLFKLYAEPSYENLKQMIQVFLYDQSLITEELLQ 188
Query 222 EQEKLMIAQSKNTQKMVDQLVAMSK--IYTPDTFAIATKSIDVPTYIIWGDQDKIINVEA 279
+ + + Q ++ + L++ K + T D A I T+I WG D+ + ++
Sbjct 189 GRWEAIQRQPEHLKNF---LISAQKAPLSTWDVTA-RLGEIKAKTFITWGRDDRFVPLDH 244
Query 280 AQELKSLLKNAETPYILKGVGH 301
+L + +A ++ GH
Sbjct 245 GLKLLWNIDDARL-HVFSKCGH 265
>Q8NFV4 sn-1-specific diacylglycerol lipase ABHD11 [Homo sapiens]
Length=306
Score = 51.6 bits (122), Expect = 9e-11
Identities = 36/114 (32%), Positives = 57/114 (50%), Gaps = 5/114 (4%)
Query 67 GNSSKPTIILIHGLAGSRDNWNRVAYNLTPY--YHVIIPDLPAHGDTKIPNDFDLSIPNL 124
G ++ P ++ +HGL GS+ N+N +A L V+ D HGD+ P+ D+S +
Sbjct 53 GEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDS--PHSPDMSYEIM 110
Query 125 TEKLRRFAEAGHFEKNVHIAGHSMGGAIALLYTAQYPLETKSLLLVDSAGVFKT 178
++ L+ V + GHSMGG A+L Q P + L+ VD + V T
Sbjct 111 SQDLQDLLPQLGLVPCV-VVGHSMGGKTAMLLALQRPELVERLIAVDISPVEST 163
>Q83WC8 Bifunctional esterase/perhydrolase DCH [Acinetobacter
calcoaceticus]
Length=276
Score = 50.8 bits (120), Expect = 1e-10
Identities = 65/278 (23%), Positives = 121/278 (44%), Gaps = 30/278 (11%)
Query 59 IEWVYSESGNSSKPTIILIHGLAGSRDNWN-RVAYNLTPYYHVIIPDLPAHG-DTKIPND 116
++ Y + G P I HG S D+W+ ++ + L + V+ D HG T++ +
Sbjct 10 VDIFYKDWGPRDAPVIFFHHGWPLSSDDWDAQMLFFLKEGFRVVAHDRRGHGRSTQVWDG 69
Query 117 FDLSIPNLTEKLRRFAEAGHFEKNVHIAGHSMGGAIALLYTAQYPLETKSLLLVDSAG-- 174
D+ + + + E + VH+ GHS GG Y A+YP + + ++ SA
Sbjct 70 HDMD--HYADDVAAVVEYLGVQGAVHV-GHSTGGGEVAYYVARYPNDPVAKAVLISAVPP 126
Query 175 -VFKTANTPYLKDPNLLNNLVVKKTGDFDKLFKLATASPPF----------IPVELKTEQ 223
+ KT + P + ++L + + + + A P + PV L +
Sbjct 127 LMVKTESNPDGLPKEVFDDLQNQLFKNRSQFYHDVPAGPFYGFNRPGAKVSEPVVLNWWR 186
Query 224 EKLMIAQSKNTQKMVDQLVAMSKIYTPDTFAIATKSIDVPTYIIWGDQDKIINVE-AAQE 282
+ +M + D +VA S+ F A K I+VP I+ G+ D+++ E + ++
Sbjct 187 QGMM----GGAKAHYDGIVAFSQ----TDFTEALKKIEVPVLILHGEDDQVVPFEISGKK 238
Query 283 LKSLLKNAETPYILKGVGH-MPILEADQLVSQQYLIFL 319
L+KN + G H MP EA + +++ L F+
Sbjct 239 SAELVKNGKL-ISYPGFPHGMPTTEA-ETINKDLLAFI 274
Lambda K H a alpha
0.319 0.136 0.397 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1330154
Database: 2508862f526b703f058c8f1750b5f34d.SwissProt.fasta
Posted date: May 20, 2024 10:34 PM
Number of letters in database: 5,601
Number of sequences in database: 17
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
