BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: b5716bd8bfc952b4eaf0bb1969554c5f.SwissProt.fasta
15 sequences; 5,599 total letters
Query= ACIAD1175
Length=378
Score E
Sequences producing significant alignments: (Bits) Value
A0A0U1RGY0 UDP-N-acetylglucosamine 2-epimerase [Neisseria meningi... 318 3e-110
Q8ZAE3 UDP-N-acetylglucosamine 2-epimerase [Yersinia pestis] 313 3e-108
P52642 UDP-N-acetylglucosamine 2-epimerase [Salmonella borreze] 310 9e-107
Q8Z388 UDP-N-acetylglucosamine 2-epimerase [Salmonella typhi] 307 9e-106
Q8XAR8 UDP-N-acetylglucosamine 2-epimerase [Escherichia coli O157... 306 3e-105
Q9L6R5 UDP-N-acetylglucosamine 2-epimerase [Salmonella typhimuriu... 306 3e-105
P39131 UDP-N-acetylglucosamine 2-epimerase [Bacillus subtilis (st... 306 3e-105
P27828 UDP-N-acetylglucosamine 2-epimerase [Escherichia coli (str... 305 4e-105
P58600 Probable UDP-N-acetylglucosamine 2-epimerase [Ralstonia ni... 302 6e-104
P45360 Putative UDP-N-acetylglucosamine 2-epimerase [Clostridium ... 300 4e-103
P52641 Probable UDP-N-acetylglucosamine 2-epimerase [Ralstonia so... 300 5e-103
Q6LZC4 UDP-N-acetylglucosamine 2-epimerase [Methanococcus maripal... 181 7e-57
G3XD61 UDP-2,3-diacetamido-2,3-dideoxy-D-glucuronate 2-epimerase ... 144 3e-43
Q6M0B4 UDP-N-acetylglucosamine 2-epimerase homolog [Methanococcus... 142 2e-42
Q5ZXH8 UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolyzing) [... 63.5 2e-14
>A0A0U1RGY0 UDP-N-acetylglucosamine 2-epimerase [Neisseria meningitidis
serogroup A / serotype 4A (strain DSM 15465 / Z2491)]
Length=372
Score = 318 bits (815), Expect = 3e-110
Identities = 161/365 (44%), Positives = 240/365 (66%), Gaps = 2/365 (1%)
Query 9 VFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKIDRRLSMMHAGQ 68
VFGTRPE IK+APVIL Q+ + +V T QH E++ + F IK D L++M Q
Sbjct 6 VFGTRPEAIKMAPVILELQKHNTITSKVCITAQHREMLDQVLSLFEIKADYDLNIMKPNQ 65
Query 69 SLNQLLIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHVEAGLRSYD 128
SL ++ ++ + V +D + +++ GDTTT AA L AF KIPV H+EAGLR+Y+
Sbjct 66 SLQEITTNIISSLTDVLEDFKP-DCVLVHGDTTTTFAASLAAFYQKIPVGHIEAGLRTYN 124
Query 129 MDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNTIVDAVYLGRELI 188
+ P+PEE NR+L S +++WHFAPTE SK+NLL+E I +D + VTGNT++DA+ + E +
Sbjct 125 LYSPWPEEANRRLTSVLSQWHFAPTEDSKNNLLSESIPSDKVIVTGNTVIDALMVSLEKL 184
Query 189 KSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFGQGIQNICDAVSALIEQYPELHFIWP 248
K + + +Q + KVILITAHRREN G+GI+NI ++ L ++YP F+ P
Sbjct 185 KITTIKKQM-EQAFPFIQDNSKVILITAHRRENHGEGIKNIGLSILELAKKYPTFSFVIP 243
Query 249 VHLNPAVHDVIHNRFDDHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGIQEESPSFHKPV 308
+HLNP V I + VHL++P +Y + ++ +S+ I++DSGGIQEE+PS KPV
Sbjct 244 LHLNPNVRKPIQDLLSSVHNVHLIEPQEYLPFVYLMSKSHIILSDSGGIQEEAPSLGKPV 303
Query 309 LILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHYHKMSNVENPFGDGHASQR 368
L+LR+TTERPE ++ G LVG++T I++ L+ +Y KM+N+ENP+G G+AS+
Sbjct 304 LVLRDTTERPEAVAAGTVKLVGSETQNIIESFTQLIEYPEYYEKMANIENPYGIGNASKI 363
Query 369 ILDKI 373
I++ +
Sbjct 364 IVETL 368
>Q8ZAE3 UDP-N-acetylglucosamine 2-epimerase [Yersinia pestis]
Length=376
Score = 313 bits (803), Expect = 3e-108
Identities = 160/365 (44%), Positives = 229/365 (63%), Gaps = 7/365 (2%)
Query 9 VFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKIDRRLSMMHAGQ 68
VFGTRPE IK+AP++ QD FE V T QH E++ + F I+ D L +M GQ
Sbjct 6 VFGTRPEAIKMAPLVHALAQDDAFESRVCVTAQHREMLDQVLRLFEIQPDYDLDIMRPGQ 65
Query 69 SLNQL---LIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHVEAGLR 125
L ++ +++GL + + FK I++ GDTTT L+A L F +IPV HVEAGLR
Sbjct 66 GLTEITCRILEGLKPVLEEFKPD----VILVHGDTTTTLSASLAGFYHRIPVGHVEAGLR 121
Query 126 SYDMDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNTIVDAVYLGR 185
+ D+ P+PEE NRQL +A +HFAPTE S+ NLL E + + I VTGNT++DA++ R
Sbjct 122 TGDLYSPWPEEANRQLTGHLAMYHFAPTENSRQNLLREWVPENRIFVTGNTVIDALFWVR 181
Query 186 ELIKSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFGQGIQNICDAVSALIEQYPELHF 245
+ + + + L Q LD K+IL+T HRRE+FG G + IC A++ + ++PE+
Sbjct 182 DRVMNTPDLRANLAQRYAFLDTNKKMILVTGHRRESFGGGFERICSALAEIARKHPEVQV 241
Query 246 IWPVHLNPAVHDVIHNRFDDHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGIQEESPSFH 305
++PVHLNP V + ++ + L+ P DY + ++ +Y I+TDSGGIQEE+PS
Sbjct 242 VYPVHLNPNVSEPVNRILKGIDNIILIDPQDYLPFVYLMNHAYLILTDSGGIQEEAPSLG 301
Query 306 KPVLILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHYHKMSNVENPFGDGHA 365
KPVL++R+TTERPE + G +LVGT+ IV LL D + YH+M+ NP+GDG+A
Sbjct 302 KPVLVMRDTTERPEAVDSGTVLLVGTNINKIVDAVTRLLTDETAYHQMTRAHNPYGDGYA 361
Query 366 SQRIL 370
QRIL
Sbjct 362 CQRIL 366
>P52642 UDP-N-acetylglucosamine 2-epimerase [Salmonella borreze]
Length=378
Score = 310 bits (793), Expect = 9e-107
Identities = 158/367 (43%), Positives = 236/367 (64%), Gaps = 2/367 (1%)
Query 6 ISIVFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKIDRRLSMMH 65
+ VFGTRPE IK+AP+++ + + EV+V TGQH E++ ++FF I+ D L++M
Sbjct 4 VLFVFGTRPEAIKMAPLVIEFKNNPAIEVKVCVTGQHREMLDQVLDFFEIEPDYDLNIMK 63
Query 66 AGQSLNQLLIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHVEAGLR 125
QSL + LT+++++ H I + GDTTT AA L AF I V H+EAGLR
Sbjct 64 QKQSLGSITCSILTRLDEILASFMPAH-IFVHGDTTTTFAASLAAFYQNIKVWHIEAGLR 122
Query 126 SYDMDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNTIVDAVYLGR 185
+++M+ PFPEEGNRQL S++A +H APT ++KDNLL E ++ I VTGNT++DA+ +G
Sbjct 123 TWNMNSPFPEEGNRQLTSKLAFFHAAPTLQAKDNLLRESVKEKNIIVTGNTVIDALLIGI 182
Query 186 ELIKSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFGQGIQNICDAVSALIEQYPELHF 245
+ I + L L+ K+IL+T HRREN G+ ++ ICD + L ++ ++
Sbjct 183 KKITGSTGDVREIISLKNKLNLDKKIILVTLHRRENQGELLRTICDDIKQLALEHDDIEI 242
Query 246 IWPVHLNPAVHDVIHNRFDDHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGIQEESPSFH 305
++PVH++P + +V++ + + LV+PL YP + ++ ++FI++DSGG+QEE+PS
Sbjct 243 VFPVHMSPRIREVVNEKLSGVVNIKLVEPLAYPGFIWLMNNAHFILSDSGGVQEEAPSLQ 302
Query 306 KPVLILRETTERPEVISVGAGVLVGTDTP-LIVKEAQHLLNDVSHYHKMSNVENPFGDGH 364
KPVL+ R+TTERPEVI GA +LV P I + LL+D Y KMS NPFGDG
Sbjct 303 KPVLVARDTTERPEVIENGAAMLVDPRIPNNIYSSCKKLLSDERLYEKMSQAGNPFGDGK 362
Query 365 ASQRILD 371
AS++ILD
Sbjct 363 ASKKILD 369
>Q8Z388 UDP-N-acetylglucosamine 2-epimerase [Salmonella typhi]
Length=376
Score = 307 bits (786), Expect = 9e-106
Identities = 155/365 (42%), Positives = 230/365 (63%), Gaps = 1/365 (0%)
Query 9 VFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKIDRRLSMMHAGQ 68
VFGTRPE IK+AP++ ++D FE +V T QH E++ + F+I D L++M GQ
Sbjct 6 VFGTRPEAIKMAPLVHALEKDPHFEAKVCVTAQHREMLDQVLTLFSIVPDYDLNIMQPGQ 65
Query 69 SLNQLLIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHVEAGLRSYD 128
L ++ + L +++ + D + +++ GDTTT +A L AF +IPV HVEAGLR+ D
Sbjct 66 GLTEITCRILERLKPILADFKP-DVVLVHGDTTTTIATSLAAFYQRIPVGHVEAGLRTGD 124
Query 129 MDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNTIVDAVYLGRELI 188
+ P+PEE NR L +A +HFAPTE S+ NLL E+I + I VTGNT++DA+ R+ +
Sbjct 125 LYSPWPEEANRTLTGHLAMYHFAPTENSRQNLLRENIPDERIFVTGNTVIDALIWVRDRV 184
Query 189 KSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFGQGIQNICDAVSALIEQYPELHFIWP 248
+ Q L + L+ K+IL+T HRRE+FGQG ++IC A++ + + ++P
Sbjct 185 LTSDTLQAELAEQYPFLNANKKMILVTGHRRESFGQGFEHICQALAEIAAANQNVQIVYP 244
Query 249 VHLNPAVHDVIHNRFDDHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGIQEESPSFHKPV 308
VHLNP V + ++ + V L++P DY + ++ ++ I+TDSGGIQEE+PS KPV
Sbjct 245 VHLNPNVSEPVNRILGHVENVVLIEPQDYLPFVWLMNHAWLILTDSGGIQEEAPSLGKPV 304
Query 309 LILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHYHKMSNVENPFGDGHASQR 368
L++RETTERPE I+ G L+GTD+ IV E LL+D + Y MS NP+GDG + R
Sbjct 305 LVMRETTERPEAITAGTVRLIGTDSRRIVAEVMRLLHDENEYQTMSRAHNPYGDGQSCAR 364
Query 369 ILDKI 373
IL +
Sbjct 365 ILQAL 369
>Q8XAR8 UDP-N-acetylglucosamine 2-epimerase [Escherichia coli
O157:H7]
Length=376
Score = 306 bits (783), Expect = 3e-105
Identities = 156/368 (42%), Positives = 229/368 (62%), Gaps = 7/368 (2%)
Query 9 VFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKIDRRLSMMHAGQ 68
VFGTRPE IK+AP++ +D FE +V T QH E++ ++ F+I D L++M GQ
Sbjct 6 VFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLDQVLKLFSIVPDYDLNIMQPGQ 65
Query 69 SLNQL---LIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHVEAGLR 125
L ++ +++GL I FK +++ GDTTT LA L AF +IPV HVEAGLR
Sbjct 66 GLTEITCRILEGLKPILAEFKPD----VVLVHGDTTTTLATSLAAFYQRIPVGHVEAGLR 121
Query 126 SYDMDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNTIVDAVYLGR 185
+ D+ P+PEE NR L +A +HF+PTE S+ NLL E++ I +TGNT++DA+ R
Sbjct 122 TGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLRENVADSRIFITGNTVIDALLWVR 181
Query 186 ELIKSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFGQGIQNICDAVSALIEQYPELHF 245
+ + S + L +DP K+IL+T HRRE+FG+G + IC A++ + + ++
Sbjct 182 DQVMSSDTLRSELAANYPFIDPDKKMILVTGHRRESFGRGFEEICHALADIATTHQDIQI 241
Query 246 IWPVHLNPAVHDVIHNRFDDHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGIQEESPSFH 305
++PVHLNP V + ++ K V L+ P +Y + ++ ++ I+TDSGGIQEE+PS
Sbjct 242 VYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPFVWLMNHAWLILTDSGGIQEEAPSLG 301
Query 306 KPVLILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHYHKMSNVENPFGDGHA 365
KPVL++R+TTERPE ++ G LVGTD IV+E LL D + Y MS NP+GDG A
Sbjct 302 KPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVEEVTRLLKDENEYQTMSRAHNPYGDGQA 361
Query 366 SQRILDKI 373
RIL+ +
Sbjct 362 CSRILEAL 369
>Q9L6R5 UDP-N-acetylglucosamine 2-epimerase [Salmonella typhimurium
(strain LT2 / SGSC1412 / ATCC 700720)]
Length=376
Score = 306 bits (783), Expect = 3e-105
Identities = 155/365 (42%), Positives = 229/365 (63%), Gaps = 1/365 (0%)
Query 9 VFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKIDRRLSMMHAGQ 68
VFGTRPE IK+AP++ ++D FE +V T QH E++ + F+I D L++M GQ
Sbjct 6 VFGTRPEAIKMAPLVHALEKDPHFEAKVCVTAQHREMLDQVLTLFSIVPDYDLNIMQPGQ 65
Query 69 SLNQLLIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHVEAGLRSYD 128
L ++ + L ++ + D + +++ GDTTT +A L AF +IPV HVEAGLR+ D
Sbjct 66 GLTEITCRILEGLKPILADFKP-DVVLVHGDTTTTIATSLAAFYQRIPVGHVEAGLRTGD 124
Query 129 MDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNTIVDAVYLGRELI 188
+ P+PEE NR L +A +HFAPTE S+ NLL E+I + I VTGNT++DA+ R+ +
Sbjct 125 LYSPWPEEANRTLTGHLAMYHFAPTENSRQNLLRENIPDERIFVTGNTVIDALIWVRDRV 184
Query 189 KSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFGQGIQNICDAVSALIEQYPELHFIWP 248
+ Q L + L+ K+IL+T HRRE+FGQG ++IC A++ + + ++P
Sbjct 185 LTSDTLQAELAEQYPFLNANKKMILVTGHRRESFGQGFEHICQALAEIAAANQNVQIVYP 244
Query 249 VHLNPAVHDVIHNRFDDHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGIQEESPSFHKPV 308
VHLNP V + ++ + V L++P DY + ++ ++ I+TDSGGIQEE+PS KPV
Sbjct 245 VHLNPNVSEPVNRILGHVENVVLIEPQDYLPFVWLMNHAWLILTDSGGIQEEAPSLGKPV 304
Query 309 LILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHYHKMSNVENPFGDGHASQR 368
L++RETTERPE I+ G L+GTD+ IV E LL+D + Y MS NP+GDG + R
Sbjct 305 LVMRETTERPEAITAGTVRLIGTDSRRIVAEVMRLLHDENEYQTMSRAHNPYGDGQSCAR 364
Query 369 ILDKI 373
IL +
Sbjct 365 ILQAL 369
>P39131 UDP-N-acetylglucosamine 2-epimerase [Bacillus subtilis
(strain 168)]
Length=380
Score = 306 bits (783), Expect = 3e-105
Identities = 160/377 (42%), Positives = 237/377 (63%), Gaps = 10/377 (3%)
Query 1 MTKQLISIVFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKIDRR 60
M K + VFGTRPE IK+AP++L ++ + V T QH +++ ++ F+IK D
Sbjct 1 MKKLKVMTVFGTRPEAIKMAPLVLELKKYPEIDSYVTVTAQHRQMLDQVLDAFHIKPDFD 60
Query 61 LSMMHAGQSLNQLLIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHV 120
L++M Q+L ++ L +++++FKD + +++ GDTTT A L AF +I V HV
Sbjct 61 LNIMKERQTLAEITSNALVRLDELFKDIKP-DIVLVHGDTTTTFAGSLAAFYHQIAVGHV 119
Query 121 EAGLRSYDMDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNTIVDA 180
EAGLR+ + PFPEE NRQ+ +A HFAPT ++KDNLL E+ +AD+I VTGNT +DA
Sbjct 120 EAGLRTGNKYSPFPEELNRQMTGAIADLHFAPTGQAKDNLLKENKKADSIFVTGNTAIDA 179
Query 181 VYLGRELIKSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFGQGIQNICDAVSALIEQY 240
+ +L Q+G DK+IL+TAHRREN G+ ++N+ A+ ++ ++
Sbjct 180 L----NTTVRDGYSHPVLDQVG-----EDKMILLTAHRRENLGEPMENMFKAIRRIVGEF 230
Query 241 PELHFIWPVHLNPAVHDVIHNRFDDHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGIQEE 300
++ ++PVHLNP V + H F D RVHL++PL+ + +S+FI+TDSGG+QEE
Sbjct 231 EDVQVVYPVHLNPVVREAAHKHFGDSDRVHLIEPLEVIDFHNFAAKSHFILTDSGGVQEE 290
Query 301 SPSFHKPVLILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHYHKMSNVENPF 360
+PS KPVL+LR+TTERPE + G L GTD I + A+ LL D Y KMS NP+
Sbjct 291 APSLGKPVLVLRDTTERPEGVEAGTLKLAGTDEENIYQLAKQLLTDPDEYKKMSQASNPY 350
Query 361 GDGHASQRILDKIATSY 377
GDG AS+RI++++ Y
Sbjct 351 GDGEASRRIVEELLFHY 367
>P27828 UDP-N-acetylglucosamine 2-epimerase [Escherichia coli
(strain K12)]
Length=376
Score = 305 bits (782), Expect = 4e-105
Identities = 156/368 (42%), Positives = 229/368 (62%), Gaps = 7/368 (2%)
Query 9 VFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKIDRRLSMMHAGQ 68
VFGTRPE IK+AP++ +D FE +V T QH E++ ++ F+I D L++M GQ
Sbjct 6 VFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLDQVLKLFSIVPDYDLNIMQPGQ 65
Query 69 SLNQL---LIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHVEAGLR 125
L ++ +++GL I FK +++ GDTTT LA L AF +IPV HVEAGLR
Sbjct 66 GLTEITCRILEGLKPILAEFKPD----VVLVHGDTTTTLATSLAAFYQRIPVGHVEAGLR 121
Query 126 SYDMDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNTIVDAVYLGR 185
+ D+ P+PEE NR L +A +HF+PTE S+ NLL E++ I +TGNT++DA+ R
Sbjct 122 TGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLRENVADSRIFITGNTVIDALLWVR 181
Query 186 ELIKSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFGQGIQNICDAVSALIEQYPELHF 245
+ + S + L +DP K+IL+T HRRE+FG+G + IC A++ + + ++
Sbjct 182 DQVMSSDKLRSELAANYPFIDPDKKMILVTGHRRESFGRGFEEICHALADIATTHQDIQI 241
Query 246 IWPVHLNPAVHDVIHNRFDDHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGIQEESPSFH 305
++PVHLNP V + ++ K V L+ P +Y + ++ ++ I+TDSGGIQEE+PS
Sbjct 242 VYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPFVWLMNHAWLILTDSGGIQEEAPSLG 301
Query 306 KPVLILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHYHKMSNVENPFGDGHA 365
KPVL++R+TTERPE ++ G LVGTD IV+E LL D + Y MS NP+GDG A
Sbjct 302 KPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVEEVTRLLKDENEYQAMSRAHNPYGDGQA 361
Query 366 SQRILDKI 373
RIL+ +
Sbjct 362 CSRILEAL 369
>P58600 Probable UDP-N-acetylglucosamine 2-epimerase [Ralstonia
nicotianae (strain GMI1000)]
Length=375
Score = 302 bits (774), Expect = 6e-104
Identities = 151/364 (41%), Positives = 231/364 (63%), Gaps = 1/364 (0%)
Query 6 ISIVFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKIDRRLSMMH 65
+ +VFGTRPE IK+AP++ Q D+ + V T QH E++ + F+I+ D L++M
Sbjct 4 VLVVFGTRPEAIKMAPLVKALQADTSMQCGVCVTAQHREMLDQVLRLFDIRPDYDLNVMK 63
Query 66 AGQSLNQLLIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHVEAGLR 125
GQ L +L LT ++ V + +++ GDT+T LA L A+ ++PV H+EAGLR
Sbjct 64 PGQDLYELTSNILTGVKSVL-ESFAPDLVLVHGDTSTTLATTLAAYYKQVPVGHIEAGLR 122
Query 126 SYDMDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNTIVDAVYLGR 185
+ ++ P+PEE NR++ +A HFAPTE+S+ NLLNE + ADA+ VTGNT++DA+ R
Sbjct 123 TGNLYSPWPEEANRKVTGSLAALHFAPTERSRRNLLNEGVPADAVVVTGNTVIDALLSVR 182
Query 186 ELIKSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFGQGIQNICDAVSALIEQYPELHF 245
+ +++ A L + +++L+T HRRE+FG G + IC A++++ +P++
Sbjct 183 QRLQTDTALCRHTASLIPYRIGERRIVLVTGHRRESFGDGFERICAALASIARAHPDVDI 242
Query 246 IWPVHLNPAVHDVIHNRFDDHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGIQEESPSFH 305
++PVHLNP V + + +HL++PLDY + ++++++ I+TDSGGIQEE+PS
Sbjct 243 VYPVHLNPNVREPVGRLLKGIDNIHLIEPLDYLPFVYLMDKAHIILTDSGGIQEEAPSLG 302
Query 306 KPVLILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHYHKMSNVENPFGDGHA 365
KPVL++R+TTERPE + G LVGT +V A LLND S Y MS NP+GDG A
Sbjct 303 KPVLVMRDTTERPEAVEAGTVRLVGTSVDALVDSATTLLNDDSAYEAMSRAHNPYGDGAA 362
Query 366 SQRI 369
S RI
Sbjct 363 SARI 366
>P45360 Putative UDP-N-acetylglucosamine 2-epimerase [Clostridium
acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG
5710 / VKM B-1787)]
Length=385
Score = 300 bits (769), Expect = 4e-103
Identities = 160/365 (44%), Positives = 223/365 (61%), Gaps = 6/365 (2%)
Query 9 VFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKIDRRLSMMHAGQ 68
+FGTRPE IK+AP++ ++ E +V T QH +++ + F+I D L++M Q
Sbjct 9 IFGTRPEAIKMAPLVRRLNENKNVESKVCVTAQHRQMLDQVLNLFDINPDFDLNIMKTKQ 68
Query 69 SLNQLLIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHVEAGLRSYD 128
+L + + L ++++F D +++ GDTTT AA L AF KI V HVEAGLR+Y+
Sbjct 69 TLTGITARVLEGLDKIFAD-ENPDIVLVHGDTTTTFAAALAAFYKKIAVGHVEAGLRTYN 127
Query 129 MDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNTIVDAVYLGRELI 188
PFPEE NR+L VA HFAPT SK NLL E + I +TGNT+VDA + +
Sbjct 128 KYFPFPEEMNRKLTGAVADLHFAPTLGSKKNLLREAVNEKNIFITGNTVVDA--MNHTVE 185
Query 189 KSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFGQGIQNICDAVSALIEQYPELHFIWP 248
K D L +L KVI++TAHRREN+G+GI+NIC A+ + E+ ++ ++
Sbjct 186 KDYVFENDELNKLDYK---NKKVIMVTAHRRENWGKGIENICTALRRIAEENEDVEIVYL 242
Query 249 VHLNPAVHDVIHNRFDDHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGIQEESPSFHKPV 308
VHLNP V DV++N + K VHL+ PLD ++ + + +MTDSGG+QEE+P KPV
Sbjct 243 VHLNPVVKDVVYNNLNGMKGVHLLPPLDTKETHNLMNKCFMVMTDSGGLQEEAPHLGKPV 302
Query 309 LILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHYHKMSNVENPFGDGHASQR 368
L+LR+ TERPE + G LVGTD IV EA ++ D Y KMS NP+GDG AS R
Sbjct 303 LVLRDVTERPEAVEAGTVKLVGTDIKKIVDEAYKIMKDEEEYEKMSKAINPYGDGKASDR 362
Query 369 ILDKI 373
I+D I
Sbjct 363 IVDAI 367
>P52641 Probable UDP-N-acetylglucosamine 2-epimerase [Ralstonia
solanacearum]
Length=375
Score = 300 bits (768), Expect = 5e-103
Identities = 150/364 (41%), Positives = 230/364 (63%), Gaps = 1/364 (0%)
Query 6 ISIVFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKIDRRLSMMH 65
+ +VFGTRPE IK+AP++ Q D+ + V T QH E++ + F+I+ D L++M
Sbjct 4 VLVVFGTRPEAIKMAPLVKALQADASLQCGVCVTAQHREMLDQVLRLFDIRPDYDLNVMK 63
Query 66 AGQSLNQLLIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHVEAGLR 125
GQ L +L LT ++ V + +++ GDT+T LA L A+ ++PV H+EAGLR
Sbjct 64 PGQDLYELTSNILTGVKSVLESFEP-DLVLVHGDTSTTLATTLAAYYKQVPVGHIEAGLR 122
Query 126 SYDMDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNTIVDAVYLGR 185
+ ++ P+PEE NR++ +A HFAPTE+S+ NLLNE + ADA+ VTGNT++DA+ R
Sbjct 123 TGNLYSPWPEEVNRKVTGSLAALHFAPTERSRRNLLNEGVPADAVVVTGNTVIDALLSVR 182
Query 186 ELIKSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFGQGIQNICDAVSALIEQYPELHF 245
+ +++ A L + +++L+T HRRE+FG G + IC ++++ +P++
Sbjct 183 QRLQTDTALCRNTASLIPYNIGERRIVLVTGHRRESFGDGFERICSTLTSIARAHPDVDI 242
Query 246 IWPVHLNPAVHDVIHNRFDDHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGIQEESPSFH 305
++PVHLNP V + + +HL++PLDY + ++++++ I+TDSGGIQEE+PS
Sbjct 243 VYPVHLNPNVREPVGRLLKGIANIHLIEPLDYLPFVYLMDKAHIILTDSGGIQEEAPSLG 302
Query 306 KPVLILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHYHKMSNVENPFGDGHA 365
KPVL++R+TTERPE + G LVGT +V A LLND S Y MS NP+GDG A
Sbjct 303 KPVLVMRDTTERPEAVEAGTVRLVGTSVDALVDSATALLNDDSAYEAMSRAHNPYGDGAA 362
Query 366 SQRI 369
S RI
Sbjct 363 SARI 366
>Q6LZC4 UDP-N-acetylglucosamine 2-epimerase [Methanococcus maripaludis
(strain S2 / LL)]
Length=366
Score = 181 bits (458), Expect = 7e-57
Identities = 118/374 (32%), Positives = 205/374 (55%), Gaps = 27/374 (7%)
Query 6 ISIVFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKIDRRLSMMH 65
I I+ GTRPE+IK++PVI F ++ T QH D I F + + + ++
Sbjct 4 IGIILGTRPEIIKMSPVIRELTTKKFF---LIHTNQHYSENMDKIFFEELNLKKPDYNLN 60
Query 66 AGQ-SLNQLLIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHVEAGL 124
G S + L +IE+V + +++QGDT TVLA L A + I + H+EAGL
Sbjct 61 IGSGSHGDQTGRMLMEIEKVLLKEKPDF-VLVQGDTNTVLAGALAASKLGIKIGHIEAGL 119
Query 125 RSYDMDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNTIVDAVYLG 184
RS+D + PEE NR L ++++ FAPT+ + +N+L E I + I + GNTIVDA
Sbjct 120 RSFD--RKMPEETNRVLTDHISEFLFAPTKTAANNILKEGISDEKIHIVGNTIVDATI-- 175
Query 185 RELIKSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFG--QGIQNICDAVSALIEQYPE 242
+ +K + + + K + + +K L+T HR EN + + + +++ + ++Y E
Sbjct 176 -QNLKIAEKNEKVCKFIS-KITKNEKYFLLTLHRAENTDNFEILSKLVTSINNISKKY-E 232
Query 243 LHFIWPVHLNPAVHDVIH-----NRFDDHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGI 297
+ I+P+H P H ++ N+ +++ + +++P+ Y L + + + I+TDSGG+
Sbjct 233 KNIIFPIH--PRTHKKLNEFGLINKLENNHLIKIIEPVGYLEFLGLEKNAELIITDSGGL 290
Query 298 QEESPSFHKPVLILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHYHKMSNVE 357
QEE+ + P + LRE TERPE + V + +L G+D I+ + +L H++
Sbjct 291 QEEACILNVPCVTLRENTERPETLDVNSNILAGSDPENILNCVEKMLKSNRHWN------ 344
Query 358 NPFGDGHASQRILD 371
NPFGDG++ + I++
Sbjct 345 NPFGDGNSGKIIVN 358
>G3XD61 UDP-2,3-diacetamido-2,3-dideoxy-D-glucuronate 2-epimerase
[Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 /
CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)]
Length=354
Score = 144 bits (364), Expect = 3e-43
Identities = 118/375 (31%), Positives = 182/375 (49%), Gaps = 31/375 (8%)
Query 6 ISIVFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKI---DRRLS 62
I + G RP+ IK + V + ++ TGQH + I F + I D +L
Sbjct 3 ILTIIGARPQFIKASVVSKAIIEQQTLSEIIVHTGQHFDANMSEIFFEQLGIPKPDYQLD 62
Query 63 MMHAGQSLNQLLIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHVEA 122
+ H G Q+ + L +IE V + H +++ GDT + LA L A + +P+AH+EA
Sbjct 63 I-HGGTH-GQMTGRMLMEIEDVILKEKP-HRVLVYGDTNSTLAGALAASKLHVPIAHIEA 119
Query 123 GLRSYDMDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVT--GNTIVDA 180
GLRS++M P EE NR L +V+ F PT + DNL NE E A + G+ + D+
Sbjct 120 GLRSFNMRMP--EEINRILTDQVSDILFCPTRVAIDNLKNEGFERKAAKIVNVGDVMQDS 177
Query 181 VYLGRELIKSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFGQGIQNICDAVSALIE-Q 239
+ S I L D IL T HR EN ++ + V AL E Q
Sbjct 178 ALFFAQRATSP-----------IGLASQDGFILATLHRAENTDDPVR-LTSIVEALNEIQ 225
Query 240 YPELHFIWPVHLNPAVHDVIHNRFDDHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGIQE 299
+ P+H P VI R V ++ P+ Y ++ +++RS ++TDSGG+Q+
Sbjct 226 INVAPVVLPLH--PRTRGVIE-RLGLKLEVQVIDPVGYLEMIWLLQRSGLVLTDSGGVQK 282
Query 300 ESPSFHKPVLILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHYHKMSNVENP 359
E+ F KP + +R+ TE E+++ GA VLVG +IV+ A+ L + +
Sbjct 283 EAFFFGKPCVTMRDQTEWVELVTCGANVLVGAARDMIVESARTSLGKT-----IQDDGQL 337
Query 360 FGDGHASQRILDKIA 374
+G G AS RI + +A
Sbjct 338 YGGGQASSRIAEYLA 352
Score = 18.9 bits (37), Expect = 3.5
Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 0/34 (0%)
Query 4 QLISIVFGTRPELIKLAPVILMAQQDSRFEVEVL 37
+L SIV I +APV+L +R +E L
Sbjct 213 RLTSIVEALNEIQINVAPVVLPLHPRTRGVIERL 246
>Q6M0B4 UDP-N-acetylglucosamine 2-epimerase homolog [Methanococcus
maripaludis (strain S2 / LL)]
Length=357
Score = 142 bits (359), Expect = 2e-42
Identities = 112/373 (30%), Positives = 192/373 (51%), Gaps = 30/373 (8%)
Query 6 ISIVFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQHDELVRDAIEFFNIKIDRRLSMMH 65
I + G RP+ IKLAPV ++ FE ++ TGQH + D I F ++I ++
Sbjct 3 IVTIVGARPQFIKLAPVSKEIRR--HFEEIIIHTGQHYDFEMDKIFFDELEIPTPNYNLN 60
Query 66 AGQSLNQLLI-QGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIPVAHVEAGL 124
G + + L +IE++ + +++ GDT + +A L + I +AHVEAGL
Sbjct 61 IGSGSHGFQTGEMLKKIEEILLKEKP-DLVLVYGDTNSTIAGALAGSKLNIKIAHVEAGL 119
Query 125 RSYDMDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNTIVDAVYLG 184
RS+D + PEE NR L ++ F PTE + NL NE I + +V G+ + D++
Sbjct 120 RSFD--RKMPEEINRVLTDHISNILFTPTETADINLKNEGINSGIFNV-GDVMYDSLLNA 176
Query 185 RELIKSKQAGQDLLKQLGIHLDPTDKVILITAHRREN--FGQGIQNICDAVSALIEQYPE 242
+LI+ K +L +L I K IL T HR EN + ++NI ++A IE +
Sbjct 177 LKLIEKKNF--KILDELNIS---KKKYILATVHRAENTDIKENLENI---INAFIESNEK 228
Query 243 LHFIWPVHLNPAVHDVIHNRFD---DHKRVHLVKPLDYPNLLAVIERSYFIMTDSGGIQE 299
+ I+PVH + + F+ ++ + L+ P+ Y ++ + + I+TDSGG+Q+
Sbjct 229 I--IFPVHPRTRKYLEKYRLFEKIKNYDNLKLISPVGYLEMIYLENNAKKILTDSGGVQK 286
Query 300 ESPSFHKPVLILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHYHKMSNVEN- 358
E+ P + LR TE E + G +LVG++ + +L ++S ++ S N
Sbjct 287 EAYFLKVPCVTLRNNTEWVETVLDGWNILVGSN-------KEKILENISKFNPASETYNY 339
Query 359 PFGDGHASQRILD 371
FG+G++S +I++
Sbjct 340 RFGEGNSSVKIVE 352
>Q5ZXH8 UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolyzing)
[Legionella pneumophila subsp. pneumophila (strain Philadelphia
1 / ATCC 33152 / DSM 7513)]
Length=377
Score = 63.5 bits (153), Expect = 2e-14
Identities = 87/385 (23%), Positives = 154/385 (40%), Gaps = 41/385 (11%)
Query 6 ISIVFGTRPELIKLAPVILMAQQDSRFEVEVLFTGQH---------DELVRDAIEFFNIK 56
I V GTR + + V+ Q ++ + TG H +E+ D I
Sbjct 5 IIYVTGTRADYGLMREVLKRLHQSEDIDLSICVTGMHLDALYGNTVNEIKADQFSICGII 64
Query 57 IDRRLSMMHAGQSLNQLLIQGLTQIEQVFKDGRTRHAIIIQGDTTTVLAAGLVAFSMKIP 116
+ H+ S+ + + L +VF + T +++ GD +LAA + A + IP
Sbjct 65 PVDLANAQHS--SMAKAIGHELLGFTEVF-ESETPDVVLLLGDRGEMLAAAIAAIHLNIP 121
Query 117 VAHVEAGLRSYDMDQPFPEEGNRQLVSRVAKWHFAPTEKSKDNLLNEHIEADAISVTGNT 176
V H+ G RS +D+ R +S+++ +HF TE SK L+ + + I G
Sbjct 122 VVHLHGGERSGTVDEMV-----RHAISKLSHYHFVATEASKQRLIRMGEKEETIFQVGAP 176
Query 177 IVDAVYLGRELIKSKQAGQDLLKQLGIHLDPTDKVILITAHRRENFGQGIQ-NICDAVSA 235
+D E+++ K + +D+ Q DP K+ L+ H I+ + A
Sbjct 177 GLD------EIMQYKTSTRDVFNQR-YGFDPDKKICLLIYHPVVQEVDSIKIQFQSVIQA 229
Query 236 LIEQYPELHFIWPV-----HLNPAVHDVIHNRFDDHKRVHLVKPLDYPNLLAVIERSYFI 290
+ ++ + P HL + +VI + DH V ++K L P + + S +
Sbjct 230 ALATNLQIICLEPNSDTGGHL---IREVIQE-YIDHPDVRIIKHLHRPEFIDCLANSDVM 285
Query 291 MTDSGGIQEESPSFHKPVLILRETTERPEVISVGAGVLVGTDTPLIVKEAQHLLNDVSHY 350
+ +S E+ SF+ V+ + E V V D I+ + LN
Sbjct 286 LGNSSSGIIEAASFNLNVVNVGSRQNLRERSDNVIDVDVTYDA--ILTGLREALNKPKIK 343
Query 351 HKMSNVENPFGDGHASQRILDKIAT 375
+ N +GDG S+R + T
Sbjct 344 YS-----NCYGDGKTSERCYQLLKT 363
Lambda K H a alpha
0.322 0.138 0.402 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1610070
Database: b5716bd8bfc952b4eaf0bb1969554c5f.SwissProt.fasta
Posted date: May 20, 2024 4:58 AM
Number of letters in database: 5,599
Number of sequences in database: 15
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
