BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 3ec9b02be0c5d668eb5e6b81ec672e79.SwissProt.fasta
14 sequences; 3,604 total letters
Query= ACIAD1347
Length=253
Score E
Sequences producing significant alignments: (Bits) Value
Q9KQA7 GTP cyclohydrolase 1 type 2 homolog [Vibrio cholerae serot... 236 1e-81
Q9CP72 GTP cyclohydrolase 1 type 2 homolog [Pasteurella multocida... 229 3e-79
Q57354 GTP cyclohydrolase 1 type 2 homolog [Haemophilus influenza... 229 6e-79
Q9HVX2 GTP cyclohydrolase 1 type 2 homolog [Pseudomonas aeruginos... 225 2e-77
Q8ZD91 GTP cyclohydrolase 1 type 2 homolog [Yersinia pestis] 223 1e-76
P45371 GTP cyclohydrolase 1 type 2 homolog [Allochromatium vinosu... 221 1e-75
Q9JXG9 GTP cyclohydrolase 1 type 2 homolog [Neisseria meningitidi... 214 2e-73
Q9JWG6 GTP cyclohydrolase 1 type 2 homolog [Neisseria meningitidi... 214 2e-73
Q8XVA0 GTP cyclohydrolase 1 type 2 homolog [Ralstonia nicotianae ... 209 2e-71
P0AFP7 GTP cyclohydrolase 1 type 2 homolog [Escherichia coli O6:H... 199 4e-67
P0AFP8 GTP cyclohydrolase 1 type 2 homolog [Escherichia coli O157... 199 4e-67
P0AFP6 GTP cyclohydrolase 1 type 2 homolog [Escherichia coli (str... 199 4e-67
P67272 GTP cyclohydrolase 1 type 2 homolog [Staphylococcus aureus... 61.2 2e-14
Q58337 GTP cyclohydrolase 1 type 2 homolog [Methanocaldococcus ja... 58.9 7e-14
>Q9KQA7 GTP cyclohydrolase 1 type 2 homolog [Vibrio cholerae serotype
O1 (strain ATCC 39315 / El Tor Inaba N16961)]
Length=252
Score = 236 bits (601), Expect = 1e-81
Identities = 119/243 (49%), Positives = 166/243 (68%), Gaps = 3/243 (1%)
Query 12 DQTLSSNQFKDYAPNGLQIEGASEVNHILCAVTASDAAIDAAIEAGANVLLVHHGYFWKG 71
++TLS KDY PNGLQ+EG EV I+ VTAS A I+AAIE A+ LLVHHGYFWK
Sbjct 11 NETLSPQLIKDYCPNGLQVEGKVEVKRIVTGVTASMALIEAAIELKADALLVHHGYFWKN 70
Query 72 EPYPITGMRGRRIKKLIQHNISLLAYHLPLDAHPSLGNNAAIADLLELKHIEALDPNEKF 131
EP I GM+GRRI+ LIQ++++L AYHLPLD HP LGNNA +A L + L+ + +
Sbjct 71 EPEAIRGMKGRRIRTLIQNDLNLYAYHLPLDIHPQLGNNAQLAQRLGICVDGGLEGHPQ- 129
Query 132 PIGNIGDLKQALSPEAFKAKLQDVFDFNIIHL-PAQVES-IQKVGFCTGGAQDFIHQAAV 189
+ G Q L+ E ++ V + +H+ P Q + I+ VG+CTGG QD+I AA
Sbjct 130 SVAMFGHFLQPLTGEELAHRIGQVLNRTPLHIAPDQADKLIETVGWCTGGGQDYIELAAS 189
Query 190 QGCDAYISGEVSERTFYEAQELNVHYYACGHHATERYGVQRLGKALSEHFSLEYTYFELN 249
+G DA+ISGE+SERT Y A+E ++HY++ GHHATERYG++ LG+ L+E+ + T+ +++
Sbjct 190 RGLDAFISGEISERTTYSAREQSIHYFSAGHHATERYGIKALGEWLAENHGFDVTFIDID 249
Query 250 NPI 252
NP+
Sbjct 250 NPV 252
>Q9CP72 GTP cyclohydrolase 1 type 2 homolog [Pasteurella multocida
(strain Pm70)]
Length=251
Score = 229 bits (585), Expect = 3e-79
Identities = 115/247 (47%), Positives = 163/247 (66%), Gaps = 2/247 (1%)
Query 6 EIVQWCDQTLSSNQFKDYAPNGLQIEGASEVNHILCAVTASDAAIDAAIEAGANVLLVHH 65
E+ Q + L+S DYAPNGLQ+EG ++ I+ VTAS A I+ A+ A+ +LVHH
Sbjct 5 ELEQILNHKLNSQAISDYAPNGLQVEGKKDIKKIITGVTASQALIEYAVSQNADAILVHH 64
Query 66 GYFWKGEPYPITGMRGRRIKKLIQHNISLLAYHLPLDAHPSLGNNAAIADLLELKHIEAL 125
GYFWK E I GM+G+RIK L+ ++I+L YHLPLD HP LGNNA +A LLE++ ++ L
Sbjct 65 GYFWKSENPCIRGMKGKRIKTLLVNDINLYGYHLPLDVHPELGNNARLAALLEIEDLQPL 124
Query 126 DPNEKFPIGNIGDLKQALSPEAFKAKLQDVFDFN-IIHLPAQVESIQKVGFCTGGAQDFI 184
+ I G LK L+ +AF A+++ V ++ I+ VG CTGG Q +I
Sbjct 125 EQG-TVSIPVYGTLKTPLTSDAFAARIEQVLKRKPLVCSDNAPHLIRTVGICTGGGQSYI 183
Query 185 HQAAVQGCDAYISGEVSERTFYEAQELNVHYYACGHHATERYGVQRLGKALSEHFSLEYT 244
AA QG DA+ISGEVSE+T + A+E +H++A GHHATERYG++ LG+ LS+H+ LE
Sbjct 184 DLAANQGVDAFISGEVSEQTIHSAREQGIHFFAAGHHATERYGIKALGEWLSQHYDLEVE 243
Query 245 YFELNNP 251
+ +++NP
Sbjct 244 FKDIDNP 250
>Q57354 GTP cyclohydrolase 1 type 2 homolog [Haemophilus influenzae
(strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=251
Score = 229 bits (583), Expect = 6e-79
Identities = 111/248 (45%), Positives = 171/248 (69%), Gaps = 4/248 (2%)
Query 6 EIVQWCDQTLSSNQFKDYAPNGLQIEGASEVNHILCAVTASDAAIDAAIEAGANVLLVHH 65
E+ Q +Q LSS++ DYAPNGLQ+EG +E+ I+ VTAS A I+ AI A+ +LVHH
Sbjct 5 ELEQLINQKLSSDKINDYAPNGLQVEGKTEIKKIITGVTASQALINYAISQNADAILVHH 64
Query 66 GYFWKGEPYPITGMRGRRIKKLIQHNISLLAYHLPLDAHPSLGNNAAIADLLELKHIEAL 125
GYFWK E I GM+G+RIK L+ ++I+L YHLPLD HP LGNNA +A LL++++++ L
Sbjct 65 GYFWKSETPCIRGMKGKRIKALLVNDINLYGYHLPLDVHPELGNNAQLAKLLDIENLQPL 124
Query 126 DPNE-KFPIGNIGDLKQALSPEAFKAKLQDVFDFN-IIHLPAQVESIQKVGFCTGGAQDF 183
+ P+ G+LK+ ++ + F K++ V + +I + I+K+G CTGG Q +
Sbjct 125 EKGSVSIPVW--GELKEPMTGKDFAEKIEKVLNRKPLICIENGPHLIRKIGICTGGGQGY 182
Query 184 IHQAAVQGCDAYISGEVSERTFYEAQELNVHYYACGHHATERYGVQRLGKALSEHFSLEY 243
I AA QGCDA+I+GEVSE+T + A+E +++++ GHHATERYG++ LG+ L++ + +
Sbjct 183 IDLAAEQGCDAFITGEVSEQTIHSAREQGLYFFSAGHHATERYGIKALGEWLAKEYGFDV 242
Query 244 TYFELNNP 251
+ +++NP
Sbjct 243 EFKDIDNP 250
>Q9HVX2 GTP cyclohydrolase 1 type 2 homolog [Pseudomonas aeruginosa
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847
/ LMG 12228 / 1C / PRS 101 / PAO1)]
Length=252
Score = 225 bits (574), Expect = 2e-77
Identities = 112/248 (45%), Positives = 162/248 (65%), Gaps = 1/248 (0%)
Query 4 LNEIVQWCDQTLSSNQFKDYAPNGLQIEGASEVNHILCAVTASDAAIDAAIEAGANVLLV 63
L+ +V+ D+ L + + +DY PNGLQ+EG +V I+ VTAS A +DAA+EA A+V+LV
Sbjct 5 LSTLVEEADRYLDAARIQDYCPNGLQVEGRPQVRRIVSGVTASQALLDAAVEADADVVLV 64
Query 64 HHGYFWKGEPYPITGMRGRRIKKLIQHNISLLAYHLPLDAHPSLGNNAAIADLLELKHIE 123
HHGYFWKGE + GM+ RR+K L+ ++ISLLAYHLPLD HP +GNN +A L +
Sbjct 65 HHGYFWKGENPCVVGMKQRRLKTLLNNDISLLAYHLPLDLHPEVGNNVQLARQLGFEVEG 124
Query 124 ALDPNEKFPIGNIGDLKQALSPEAFKAKLQDVFDFNIIHLPAQVESIQKVGFCTGGAQDF 183
L+P I +G L + + P F ++D + + A + I+++ +CTGGAQ +
Sbjct 125 PLEPGNPRSIVLLGSLAEPMQPADFARHVRDALGREPLLVDAG-QPIRRIAWCTGGAQGY 183
Query 184 IHQAAVQGCDAYISGEVSERTFYEAQELNVHYYACGHHATERYGVQRLGKALSEHFSLEY 243
I QA G DAY++GEVSE+T + A+E + + A GHHATERYGVQ LG L + F++E+
Sbjct 184 IDQAIAAGVDAYLTGEVSEQTVHSARENGISFIAAGHHATERYGVQALGDYLGKRFAIEH 243
Query 244 TYFELNNP 251
+ + NP
Sbjct 244 LFIDCPNP 251
>Q8ZD91 GTP cyclohydrolase 1 type 2 homolog [Yersinia pestis]
Length=247
Score = 223 bits (568), Expect = 1e-76
Identities = 108/241 (45%), Positives = 162/241 (67%), Gaps = 12/241 (5%)
Query 15 LSSNQFKDYAPNGLQIEGASEVNHILCAVTASDAAIDAAIEAGANVLLVHHGYFWKGEPY 74
L+ F+DYAPNGLQ+EG ++ ++ VTAS A +DAA+ A+ +LVHHGYFWK EP
Sbjct 14 LNIGAFQDYAPNGLQVEGRRDIQRVVTGVTASQALLDAAVAHQADAILVHHGYFWKNEPV 73
Query 75 PITGMRGRRIKKLIQHNISLLAYHLPLDAHPSLGNNAAIADLLELK---HIEALDPNEKF 131
+ GM+ R+K L+ H+I+L YHLPLDAHP LGNNA +A LLE++ IE+L P
Sbjct 74 VVRGMKRNRLKTLLTHDINLYGYHLPLDAHPELGNNAQLAKLLEIQVLGEIESLLP---- 129
Query 132 PIGNIGDLKQALSPEAFKAKLQDVFDFNIIHLPAQVES-IQKVGFCTGGAQDFIHQAAVQ 190
G+ L+ A + +L+ +++H + + ++++ +CTGG Q +I QAA
Sbjct 130 ----YGEFTTPLNAVALRERLEKQLGRSVLHCGDRAPAEVRRIAWCTGGGQGYIQQAAEF 185
Query 191 GCDAYISGEVSERTFYEAQELNVHYYACGHHATERYGVQRLGKALSEHFSLEYTYFELNN 250
G DA+I+GEVSE+T + A+E+ V++YA GHHATERYG++ LG+ L+E + L+ T+ ++ N
Sbjct 186 GVDAFITGEVSEQTIHIAREMKVNFYAAGHHATERYGIKALGEWLAEQYQLDVTFIDIPN 245
Query 251 P 251
P
Sbjct 246 P 246
>P45371 GTP cyclohydrolase 1 type 2 homolog [Allochromatium vinosum
(strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441
/ D)]
Length=254
Score = 221 bits (562), Expect = 1e-75
Identities = 110/255 (43%), Positives = 163/255 (64%), Gaps = 10/255 (4%)
Query 1 MAHLNEIVQWCDQTLSSNQFKDYAPNGLQIEGASEVNHILCAVTASDAAIDAAIEAGANV 60
M + +++++CD L + +F DYAPNGLQ+EG + ++ VTAS A I+AAI A+
Sbjct 5 MTDVRDLIRYCDDVLDAARFADYAPNGLQVEGERPLQRLVSGVTASAALIEAAIAEHADA 64
Query 61 LLVHHGYFWKGEPYPITGMRGRRIKKLIQHNISLLAYHLPLDAHPSLGNNAAIADLLELK 120
+LVHHG+FWK E + G++G+R + L+ +SL+AYHLPLDAHP LGNNA + L+
Sbjct 65 ILVHHGWFWKNENPCLIGIKGQRARTLLSAGVSLIAYHLPLDAHPELGNNATLGRRLDFI 124
Query 121 HIEALDPNEKFPIGN----IGDLKQALSPEAFKAKLQDVFDFNIIHLPAQVESIQKVGFC 176
+E + N +G L Q ++P +F + + + + SI++V +C
Sbjct 125 DMEPT------ALANGLLWVGRLAQPMTPASFTEHVSQRLARPALRVGRETGSIERVAWC 178
Query 177 TGGAQDFIHQAAVQGCDAYISGEVSERTFYEAQELNVHYYACGHHATERYGVQRLGKALS 236
TGG Q +I QAA G DA++SGE+SE+T ++A+EL + Y A GHHATERYGVQ LGK L+
Sbjct 179 TGGCQGYIEQAASLGVDAFLSGELSEQTTHQARELGLCYLAAGHHATERYGVQALGKHLA 238
Query 237 EHFSLEYTYFELNNP 251
E F L + + E++NP
Sbjct 239 ERFGLWHRFVEIDNP 253
>Q9JXG9 GTP cyclohydrolase 1 type 2 homolog [Neisseria meningitidis
serogroup B (strain MC58)]
Length=249
Score = 214 bits (546), Expect = 2e-73
Identities = 109/251 (43%), Positives = 155/251 (62%), Gaps = 3/251 (1%)
Query 1 MAHLNEIVQWCDQTLSSNQFKDYAPNGLQIEGASEVNHILCAVTASDAAIDAAIEAGANV 60
M + + WC++TL + FKDYAPNGLQ+EG + I+ +VTAS AAID A+E A++
Sbjct 1 MVLCRDFLTWCNETLQTALFKDYAPNGLQVEGREYIGKIVTSVTASRAAIDFAVEQKADL 60
Query 61 LLVHHGYFWKGEPYPITGMRGRRIKKLIQHNISLLAYHLPLDAHPSLGNNAAIADLLELK 120
LLVHHG FWK E +TG + RI L++H+I++ YHLPLDAHP+LGNNA +AD L
Sbjct 61 LLVHHGMFWKNELPTVTGWKKERIAALLRHDINMAGYHLPLDAHPTLGNNAQLADRLGFA 120
Query 121 HIEALDPNEKFPIGNIGDLKQALSPEAFKAKLQDVFDFNIIHLPAQVESIQKVGFCTGGA 180
+ + N G LKQA + A A ++ V + + I++V +C+GGA
Sbjct 121 TEKRFGEQN---LLNSGSLKQAKTLGALAAHIETVLQRKPVVIGNPEREIRRVAWCSGGA 177
Query 181 QDFIHQAAVQGCDAYISGEVSERTFYEAQELNVHYYACGHHATERYGVQRLGKALSEHFS 240
Q F A +G D Y++GE+SE ++ A E + + GHHATERYGV+ L ++ +E F
Sbjct 178 QGFFQTAIDEGVDLYLTGEISEAQYHLANETGTAFISAGHHATERYGVRALAESAAEVFG 237
Query 241 LEYTYFELNNP 251
LE +F+ NNP
Sbjct 238 LEVCHFDENNP 248
>Q9JWG6 GTP cyclohydrolase 1 type 2 homolog [Neisseria meningitidis
serogroup A / serotype 4A (strain DSM 15465 / Z2491)]
Length=249
Score = 214 bits (546), Expect = 2e-73
Identities = 108/246 (44%), Positives = 154/246 (63%), Gaps = 3/246 (1%)
Query 6 EIVQWCDQTLSSNQFKDYAPNGLQIEGASEVNHILCAVTASDAAIDAAIEAGANVLLVHH 65
+ + WC++TL + FKDYAPNGLQ+EG + I+ +VTAS AAID A+E A++LLVHH
Sbjct 6 DFLTWCNETLQTALFKDYAPNGLQVEGREYIGKIVTSVTASRAAIDFAVEQKADLLLVHH 65
Query 66 GYFWKGEPYPITGMRGRRIKKLIQHNISLLAYHLPLDAHPSLGNNAAIADLLELKHIEAL 125
G FWK E +TG + RI L++H+I++ YHLPLDAHP+LGNNA +AD L +
Sbjct 66 GMFWKNELPTVTGWKKERIAALLRHDINMAGYHLPLDAHPTLGNNAQLADRLGFATEKRF 125
Query 126 DPNEKFPIGNIGDLKQALSPEAFKAKLQDVFDFNIIHLPAQVESIQKVGFCTGGAQDFIH 185
+ N G LKQA + A A ++ V + + I++V +C+GGAQ F
Sbjct 126 GEQN---LLNSGSLKQAKTLGALAAHIETVLQRKPVVIGKPEREIRRVAWCSGGAQGFFQ 182
Query 186 QAAVQGCDAYISGEVSERTFYEAQELNVHYYACGHHATERYGVQRLGKALSEHFSLEYTY 245
A +G D Y++GE+SE ++ A E + + GHHATERYGV+ L ++ +E F LE +
Sbjct 183 TAIDEGVDLYLTGEISEAQYHLANETGTAFISAGHHATERYGVRALAESAAEVFGLEVCH 242
Query 246 FELNNP 251
F+ NNP
Sbjct 243 FDENNP 248
>Q8XVA0 GTP cyclohydrolase 1 type 2 homolog [Ralstonia nicotianae
(strain GMI1000)]
Length=248
Score = 209 bits (533), Expect = 2e-71
Identities = 105/247 (43%), Positives = 154/247 (62%), Gaps = 3/247 (1%)
Query 6 EIVQWCDQTLSSNQFKDYAPNGLQIEGASEVNHILCAVTASDAAIDAAIEAGANVLLVHH 65
E+ + + L + +F+DY PNGLQ++G + HI+ VTAS A I+AAI+ A+ +LVHH
Sbjct 5 ELELYLNDLLQAARFRDYCPNGLQVQGRDPIAHIVTGVTASLALIEAAIDVRADAILVHH 64
Query 66 GYFWKGEPYPITGMRGRRIKKLIQHNISLLAYHLPLDAHPSLGNNAAIADLLELKHIEAL 125
GYFWKGE + G + R+K+L+ H+++L AYHLPLDAHP+LGNNA + LL ++
Sbjct 65 GYFWKGEDARVIGQKHARLKQLLAHDVNLFAYHLPLDAHPTLGNNAQLGALLGIQPTGRF 124
Query 126 DPNEKFPIGNIGDLKQALSPEAFKAKLQDVFDFNIIHLPAQVESIQKVGFCTGGAQDFIH 185
+E +G IG L +A + AF + D + + + +G+CTGGAQ +
Sbjct 125 GDDE---LGWIGTLPEATTLGAFAEVVAARLDRMPLVIGGADRPVHTIGWCTGGAQGWFD 181
Query 186 QAAVQGCDAYISGEVSERTFYEAQELNVHYYACGHHATERYGVQRLGKALSEHFSLEYTY 245
A G D Y+SGE SE+T + A+E V Y GHHATER GV+ LG L+EHF + +T+
Sbjct 182 AAVSAGVDVYLSGEASEQTTHLARESGVAYIGAGHHATERGGVRALGNHLAEHFGVRHTF 241
Query 246 FELNNPI 252
++ NP+
Sbjct 242 IDIPNPV 248
>P0AFP7 GTP cyclohydrolase 1 type 2 homolog [Escherichia coli
O6:H1 (strain CFT073 / ATCC 700928 / UPEC)]
Length=247
Score = 199 bits (505), Expect = 4e-67
Identities = 107/251 (43%), Positives = 153/251 (61%), Gaps = 14/251 (6%)
Query 6 EIVQWCDQTLSSNQFKDYAPNGLQIEGASEVNHILCAVTASDAAIDAAIEAGANVLLVHH 65
E+ Q ++ L+S DYAPNGLQ+EG V I+ VTAS A +D A+ GA+ ++VHH
Sbjct 5 ELEQLINEKLNSAAISDYAPNGLQVEGKETVQKIVTGVTASQALLDEAVRLGADAVIVHH 64
Query 66 GYFWKGEPYPITGMRGRRIKKLIQHNISLLAYHLPLDAHPSLGNNAAIADLLELKHIEAL 125
GYFWKGE I GM+ R+K L+ ++I+L +HLPLDAHP LGNNA +A LL + + +
Sbjct 65 GYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDAHPELGNNAQLAALLGITVMGEI 124
Query 126 DPNEKFPIGNIGDLKQALSPEAFKAKLQDVFDFNIIHLP-----AQVESIQKVGFCTGGA 180
+P P G L+ +L + + P E +Q+V +CTGG
Sbjct 125 EP--LVPWGE-------LTMPVPGLELASWIEARLGRKPLWCGDTGPEVVQRVAWCTGGG 175
Query 181 QDFIHQAAVQGCDAYISGEVSERTFYEAQELNVHYYACGHHATERYGVQRLGKALSEHFS 240
Q FI AA G DA+I+GEVSE+T + A+E +H+YA GHHATER G++ L + L+E+
Sbjct 176 QSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHATERGGIRALSEWLNENTD 235
Query 241 LEYTYFELNNP 251
L+ T+ ++ NP
Sbjct 236 LDVTFIDIPNP 246
>P0AFP8 GTP cyclohydrolase 1 type 2 homolog [Escherichia coli
O157:H7]
Length=247
Score = 199 bits (505), Expect = 4e-67
Identities = 107/251 (43%), Positives = 153/251 (61%), Gaps = 14/251 (6%)
Query 6 EIVQWCDQTLSSNQFKDYAPNGLQIEGASEVNHILCAVTASDAAIDAAIEAGANVLLVHH 65
E+ Q ++ L+S DYAPNGLQ+EG V I+ VTAS A +D A+ GA+ ++VHH
Sbjct 5 ELEQLINEKLNSAAISDYAPNGLQVEGKETVQKIVTGVTASQALLDEAVRLGADAVIVHH 64
Query 66 GYFWKGEPYPITGMRGRRIKKLIQHNISLLAYHLPLDAHPSLGNNAAIADLLELKHIEAL 125
GYFWKGE I GM+ R+K L+ ++I+L +HLPLDAHP LGNNA +A LL + + +
Sbjct 65 GYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDAHPELGNNAQLAALLGITVMGEI 124
Query 126 DPNEKFPIGNIGDLKQALSPEAFKAKLQDVFDFNIIHLP-----AQVESIQKVGFCTGGA 180
+P P G L+ +L + + P E +Q+V +CTGG
Sbjct 125 EP--LVPWGE-------LTMPVPGLELASWIEARLGRKPLWCGDTGPEVVQRVAWCTGGG 175
Query 181 QDFIHQAAVQGCDAYISGEVSERTFYEAQELNVHYYACGHHATERYGVQRLGKALSEHFS 240
Q FI AA G DA+I+GEVSE+T + A+E +H+YA GHHATER G++ L + L+E+
Sbjct 176 QSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHATERGGIRALSEWLNENTD 235
Query 241 LEYTYFELNNP 251
L+ T+ ++ NP
Sbjct 236 LDVTFIDIPNP 246
>P0AFP6 GTP cyclohydrolase 1 type 2 homolog [Escherichia coli
(strain K12)]
Length=247
Score = 199 bits (505), Expect = 4e-67
Identities = 107/251 (43%), Positives = 153/251 (61%), Gaps = 14/251 (6%)
Query 6 EIVQWCDQTLSSNQFKDYAPNGLQIEGASEVNHILCAVTASDAAIDAAIEAGANVLLVHH 65
E+ Q ++ L+S DYAPNGLQ+EG V I+ VTAS A +D A+ GA+ ++VHH
Sbjct 5 ELEQLINEKLNSAAISDYAPNGLQVEGKETVQKIVTGVTASQALLDEAVRLGADAVIVHH 64
Query 66 GYFWKGEPYPITGMRGRRIKKLIQHNISLLAYHLPLDAHPSLGNNAAIADLLELKHIEAL 125
GYFWKGE I GM+ R+K L+ ++I+L +HLPLDAHP LGNNA +A LL + + +
Sbjct 65 GYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDAHPELGNNAQLAALLGITVMGEI 124
Query 126 DPNEKFPIGNIGDLKQALSPEAFKAKLQDVFDFNIIHLP-----AQVESIQKVGFCTGGA 180
+P P G L+ +L + + P E +Q+V +CTGG
Sbjct 125 EP--LVPWGE-------LTMPVPGLELASWIEARLGRKPLWCGDTGPEVVQRVAWCTGGG 175
Query 181 QDFIHQAAVQGCDAYISGEVSERTFYEAQELNVHYYACGHHATERYGVQRLGKALSEHFS 240
Q FI AA G DA+I+GEVSE+T + A+E +H+YA GHHATER G++ L + L+E+
Sbjct 176 QSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHATERGGIRALSEWLNENTD 235
Query 241 LEYTYFELNNP 251
L+ T+ ++ NP
Sbjct 236 LDVTFIDIPNP 246
>P67272 GTP cyclohydrolase 1 type 2 homolog [Staphylococcus aureus
(strain Mu50 / ATCC 700699)]
Length=366
Score = 61.2 bits (147), Expect = 2e-14
Identities = 40/122 (33%), Positives = 61/122 (50%), Gaps = 9/122 (7%)
Query 31 EGASEVNHILCAVTASDAAIDAAIEAGANVLLVHHGYFWKGEPYPITGMRGRRIKKLIQH 90
+G EV +L A+ + ++ AIE G N ++ HH +KG G I+KLIQH
Sbjct 31 DGDVEVTGVLTALDCTLEVVNEAIEKGYNTIISHHPLIFKGVTSLKANGYGLIIRKLIQH 90
Query 91 NISLLAYHLPLDAHPSLGNNAAIADLLELKHIEALDPNEK--------FPIGNIGDLKQA 142
+I+L+A H LD +P G N +A + LK+I ++ + P N+G K
Sbjct 91 DINLIAMHTNLDVNP-YGVNMMLAKAMGLKNISIINNQQDVYYKVQTYIPKDNVGPFKDK 149
Query 143 LS 144
LS
Sbjct 150 LS 151
Score = 32.0 bits (71), Expect = 9e-05
Identities = 18/111 (16%), Positives = 49/111 (44%), Gaps = 7/111 (6%)
Query 113 IADLLELKHIEALDPNEKFPIGNIGDLKQALSPEAFKAKLQDVFDFNIIHLPAQV-ESIQ 171
+ D +E+K + +G + ++ ++ E F A ++ + + + + I+
Sbjct 224 VFDFIEIKQTSL------YGLGVMAEVDNQMTLEDFAADIKSKLNIPSVRFVGESNQKIK 277
Query 172 KVGFCTGGAQDFIHQAAVQGCDAYISGEVSERTFYEAQELNVHYYACGHHA 222
++ G + +QA QG D +++G++ +A+ V+ H++
Sbjct 278 RIAIIGGSGIGYEYQAVQQGADVFVTGDIKHHDALDAKIHGVNLIDINHYS 328
>Q58337 GTP cyclohydrolase 1 type 2 homolog [Methanocaldococcus
jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045
/ NBRC 100440)]
Length=244
Score = 58.9 bits (141), Expect = 7e-14
Identities = 57/232 (25%), Positives = 108/232 (47%), Gaps = 18/232 (8%)
Query 23 YAPNGLQIEGAS-----------EVNHILCAVTASDAAIDAAIEAGANVLLVHHGYFWKG 71
+AP L IEG + E+ + A+ S + I A + G + L HH K
Sbjct 13 FAPKDLAIEGDNIGLQVGDNLDKEIKKLGIALDPSLSVIKKAEKEGVDFLFTHHPLL-KD 71
Query 72 EPYPITGMRGRRIKKLIQHNISLLAYHLPLDAHPSLGNNAAIADLLELKHIEALDPNEKF 131
TG+ +++K L++++I L + H LD + G N A+A+L L++ + L N
Sbjct 72 PIRNFTGVIYKKLKILMENDIILYSAHTNLDICKN-GLNDALAELYNLENPKPLYDNG-- 128
Query 132 PIGNIGDLKQALSPEAFKAKLQDVFDFNIIHLPAQVESIQKVGFCTG-GAQDFIHQAAVQ 190
+G +G K + E + + + I+ +V+ K+ +G G + +
Sbjct 129 -LGRVGIFKGSFE-EFLEITKKYIHKNPIVVKSKEVDDNFKLAVLSGYGLSQSSIKYVAE 186
Query 191 GCDAYISGEVSERTFYEAQELNVHYYACGHHATERYGVQRLGKALSEHFSLE 242
D Y+SG+++ + A+EL + H++TE +G+++ + LS + LE
Sbjct 187 KADVYLSGDLTHHSKILAEELGLVVVDATHYSTEVFGLKKFKEFLSSNLDLE 238
Lambda K H a alpha
0.322 0.138 0.420 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 636376
Database: 3ec9b02be0c5d668eb5e6b81ec672e79.SwissProt.fasta
Posted date: May 20, 2024 4:40 PM
Number of letters in database: 3,604
Number of sequences in database: 14
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
