BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: 24e56caba3610cbc1bd6b4e60516abc1.SwissProt.fasta
           19 sequences; 4,815 total letters



Query= ACIAD1650

Length=234
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q8A3H9 NAD-dependent protein deacylase [Bacteroides thetaiotaomic...  224     2e-77
O25849 NAD-dependent protein deacylase [Helicobacter pylori (stra...  211     2e-72
Q9ZJW8 NAD-dependent protein deacylase [Helicobacter pylori (stra...  206     2e-70
Q9ZAB8 NAD-dependent protein deacylase [Aggregatibacter actinomyc...  204     8e-70
Q669P6 NAD-dependent protein deacylase [Yersinia pseudotuberculos...  176     3e-58
Q8ZFR1 NAD-dependent protein deacylase [Yersinia pestis]              176     3e-58
B4EVF5 NAD-dependent protein deacylase [Proteus mirabilis (strain...  175     1e-57
Q9KRX4 NAD-dependent protein deacylase [Vibrio cholerae serotype ...  168     3e-55
Q83RR8 NAD-dependent protein deacylase [Shigella flexneri]            168     6e-55
Q8FIM4 NAD-dependent protein deacylase [Escherichia coli O6:H1 (s...  167     8e-55
Q8X8E0 NAD-dependent protein deacylase [Escherichia coli O157:H7]     167     8e-55
P75960 NAD-dependent protein deacylase [Escherichia coli (strain ...  167     1e-54
Q584D5 NAD-dependent protein deacylase SIR2rp3 [Trypanosoma bruce...  166     2e-54
P0A2F2 NAD-dependent protein deacylase [Salmonella typhimurium (s...  166     2e-54
O28597 NAD-dependent protein deacylase 1 [Archaeoglobus fulgidus ...  148     1e-47
A0R2N3 NAD-dependent protein deacylase Sir2 [Mycolicibacterium sm...  136     6e-43
P9WGG3 NAD-dependent protein deacylase [Mycobacterium tuberculosi...  133     9e-42
Q9JN05 NAD-dependent protein deacylase [Campylobacter jejuni subs...  127     2e-39
O30124 NAD-dependent protein deacylase 2 [Archaeoglobus fulgidus ...  126     4e-39


>Q8A3H9 NAD-dependent protein deacylase [Bacteroides thetaiotaomicron 
(strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 
/ NCTC 10582 / VPI-5482 / E50)]
Length=234

 Score = 224 bits (570),  Expect = 2e-77
 Identities = 108/228 (47%), Positives = 160/228 (70%), Gaps = 4/228 (2%)

Query  1    MKKLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNI  60
            MK LVV +GAGMSAESGI TFRD  GLW+ Y +E+VATPE +Q++P+LV +FYN RRK +
Sbjct  1    MKNLVVLTGAGMSAESGISTFRDAGGLWDKYPVEQVATPEGYQRDPALVINFYNARRKQL  60

Query  61   LAAQPNLAHQIIAQLESCYQVQVITQNIDDLHERAGSTHVLHLHGNI-RLAKSSGP-NAQ  118
            L  +PN  H+++A+LE  + V VITQN+D+LHERAGS+H++HLHG + ++  S  P N  
Sbjct  61   LEVKPNRGHELLAELEKNFNVTVITQNVDNLHERAGSSHIVHLHGELTKVCSSRDPYNPH  120

Query  119  FTQTFYPIDGWQLDLNQDKCNEGYPLRPHVVWFGEAVPAYDDAIAMLKDADVFIVIGSTL  178
            + +   P + +++ +  DK  +G  LRP +VWFGEAVP  + A+  ++ AD+F++IG++L
Sbjct  121  YIKELKP-EEYEVKMG-DKAGDGTQLRPFIVWFGEAVPEIETAVRYVEKADIFVIIGTSL  178

Query  179  SVYPVAGLIHEIPNHCEAYYIDPQADYFRVPHQYTLLKMTATEGMKQL  226
            +VYP AGL+H +P   E Y IDP+           +L+  A+EG+++L
Sbjct  179  NVYPAAGLLHYVPRGAEVYLIDPKPVDTHTSRSIHVLRKGASEGVEEL  226


>O25849 NAD-dependent protein deacylase [Helicobacter pylori (strain 
ATCC 700392 / 26695)]
Length=229

 Score = 211 bits (537),  Expect = 2e-72
 Identities = 109/232 (47%), Positives = 144/232 (62%), Gaps = 10/232 (4%)

Query  1    MKKLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNI  60
            MK LV+ SGAG+SAESGI TFRD DGLWE + I EVA+P  W++NP  V  FYN+RR+ +
Sbjct  1    MKNLVILSGAGISAESGIKTFRDADGLWEGHDIMEVASPYGWKKNPQKVLDFYNQRRRQL  60

Query  61   LAAQPNLAHQIIAQLESCYQVQVITQNIDDLHERAGSTHVLHLHGNIRLAKS-SGPNAQF  119
                PN AH+ +A+LE  YQV +ITQN+DDLHERAGS+ +LHLHG +   +S   PN  +
Sbjct  61   FEVYPNKAHKALAELEKHYQVNIITQNVDDLHERAGSSRILHLHGELLSVRSEKDPNLVY  120

Query  120  TQTFYPIDGWQLDLN-QDKCNEGYPLRPHVVWFGEAVPAYDDAIAMLKDADVFIVIGSTL  178
                     W+ DLN  D   +   LRP +VWFGEAVP   +AI+++K A + I+IG++L
Sbjct  121  R--------WEKDLNLGDLAKDKSQLRPDIVWFGEAVPLLKEAISLVKQAHLLIIIGTSL  172

Query  179  SVYPVAGLIHEIPNHCEAYYIDPQADYFRVPHQYTLLKMTATEGMKQLYLKL  230
             VYP A L          YYIDP+A    +P     +  +A   M+ L  KL
Sbjct  173  QVYPAASLYTHAHKDALIYYIDPKAKNAHLPQNVQCINESAVHAMQDLMPKL  224


>Q9ZJW8 NAD-dependent protein deacylase [Helicobacter pylori (strain 
J99 / ATCC 700824)]
Length=234

 Score = 206 bits (524),  Expect = 2e-70
 Identities = 106/232 (46%), Positives = 141/232 (61%), Gaps = 10/232 (4%)

Query  1    MKKLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNI  60
            MK LV+ SGAG+SAESGI TFRD  GLWE + I EVA+P  W++NP  V  FYN+RR+ +
Sbjct  1    MKNLVILSGAGISAESGIKTFRDAGGLWEGHDIMEVASPYGWKKNPQKVLDFYNQRRRQL  60

Query  61   LAAQPNLAHQIIAQLESCYQVQVITQNIDDLHERAGSTHVLHLHGNIRLAKS-SGPNAQF  119
                PN AH+ +A+LE  YQV +ITQN+DDLHERAGS+ +LHLHG +   +S   PN  +
Sbjct  61   FEVYPNKAHKALAELEKHYQVNIITQNVDDLHERAGSSRILHLHGELLSVRSEKDPNLVY  120

Query  120  TQTFYPIDGWQLDLN-QDKCNEGYPLRPHVVWFGEAVPAYDDAIAMLKDADVFIVIGSTL  178
                     W+ DLN  D   +   LRP +VWFGE VP   +A++++K   + I+IG++L
Sbjct  121  R--------WEKDLNLGDLAQDKAQLRPDIVWFGEEVPLLKEAVSLVKQVHLLIIIGTSL  172

Query  179  SVYPVAGLIHEIPNHCEAYYIDPQADYFRVPHQYTLLKMTATEGMKQLYLKL  230
             VYP A L          YYIDP+A   R+P     +   A   M+ L  KL
Sbjct  173  QVYPAASLYTHANKDALIYYIDPKAKNARLPQNVQCINENAVHAMQDLMPKL  224


>Q9ZAB8 NAD-dependent protein deacylase [Aggregatibacter actinomycetemcomitans]
Length=208

 Score = 204 bits (518),  Expect = 8e-70
 Identities = 103/197 (52%), Positives = 138/197 (70%), Gaps = 6/197 (3%)

Query  5    VVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNILAAQ  64
            VV SGAG+SAESGI T+R  DGLW  ++IE+V TPEA Q+N   V  FYNERR+N   A+
Sbjct  6    VVLSGAGISAESGIPTYRAEDGLWAGHKIEDVCTPEALQRNRKQVLAFYNERRRNCAEAK  65

Query  65   PNLAHQIIAQLESCYQVQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSGPNAQFTQTFY  124
            PN AH+++ +LE  Y VQ+ITQN++DLHERAGST+VLHLHG +  A+SS           
Sbjct  66   PNAAHKVLVELERSYNVQIITQNVEDLHERAGSTNVLHLHGELTKARSSFD----PDYIV  121

Query  125  PIDGWQLDLNQDKCNEGYPLRPHVVWFGEAVPAYDDAIAMLKDADVFIVIGSTLSVYPVA  184
            P  G Q  +N DK   G+P+RPH+V+FGE+VP  + AI ++  AD+ +VIG++L VYP  
Sbjct  122  PCMGDQ-SVN-DKDPNGHPMRPHIVFFGESVPVLEPAIDLVSQADIVLVIGTSLQVYPAN  179

Query  185  GLIHEIPNHCEAYYIDP  201
            GL++E P + + Y IDP
Sbjct  180  GLVNEAPKNAQIYLIDP  196


>Q669P6 NAD-dependent protein deacylase [Yersinia pseudotuberculosis 
serotype I (strain IP32953)]
Length=278

 Score = 176 bits (447),  Expect = 3e-58
 Identities = 99/203 (49%), Positives = 130/203 (64%), Gaps = 18/203 (9%)

Query  1    MKK--LVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRK  58
            MKK  +VV +GAG+SAESGI TFR  DGLWE++R+E+VATPE ++++P LVQ FYNERR+
Sbjct  36   MKKPFVVVLTGAGISAESGIRTFRADDGLWEDHRVEDVATPEGYRRDPELVQRFYNERRR  95

Query  59   NILAAQ--PNLAHQIIAQLESCY--QVQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSG  114
             +      PN AH  +A LE+     + +ITQNID+LHERAGS  V+H+HG +       
Sbjct  96   QLQQPDIAPNAAHFALADLEAVLGDNLVLITQNIDNLHERAGSKRVIHMHGELL------  149

Query  115  PNAQFTQTFYPIDGWQLDLNQDK----CNEGYPLRPHVVWFGEAVPAYDDAIAMLKDADV  170
               + TQ+   +D WQ DL+ D+    C    PLRPH+VWFGE     DD    L +AD 
Sbjct  150  -KVRCTQSGQVLD-WQGDLSADERCHCCQFPSPLRPHIVWFGEMPMGMDDIYQALAEADF  207

Query  171  FIVIGSTLSVYPVAGLIHEIPNH  193
            FI IG++  VYP AG +HE   H
Sbjct  208  FISIGTSGHVYPAAGFVHESHLH  230


>Q8ZFR1 NAD-dependent protein deacylase [Yersinia pestis]
Length=278

 Score = 176 bits (447),  Expect = 3e-58
 Identities = 99/203 (49%), Positives = 130/203 (64%), Gaps = 18/203 (9%)

Query  1    MKK--LVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRK  58
            MKK  +VV +GAG+SAESGI TFR  DGLWE++R+E+VATPE ++++P LVQ FYNERR+
Sbjct  36   MKKPFVVVLTGAGISAESGIRTFRADDGLWEDHRVEDVATPEGYRRDPELVQRFYNERRR  95

Query  59   NILAAQ--PNLAHQIIAQLESCY--QVQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSG  114
             +      PN AH  +A LE+     + +ITQNID+LHERAGS  V+H+HG +       
Sbjct  96   QLQQPDIAPNAAHFALADLEAVLGDNLVLITQNIDNLHERAGSKRVIHMHGELL------  149

Query  115  PNAQFTQTFYPIDGWQLDLNQDK----CNEGYPLRPHVVWFGEAVPAYDDAIAMLKDADV  170
               + TQ+   +D WQ DL+ D+    C    PLRPH+VWFGE     DD    L +AD 
Sbjct  150  -KVRCTQSGQVLD-WQGDLSADERCHCCQFPSPLRPHIVWFGEMPMGMDDIYQALAEADF  207

Query  171  FIVIGSTLSVYPVAGLIHEIPNH  193
            FI IG++  VYP AG +HE   H
Sbjct  208  FISIGTSGHVYPAAGFVHESHLH  230


>B4EVF5 NAD-dependent protein deacylase [Proteus mirabilis (strain 
HI4320)]
Length=285

 Score = 175 bits (444),  Expect = 1e-57
 Identities = 94/198 (47%), Positives = 125/198 (63%), Gaps = 17/198 (9%)

Query  1    MKKLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNI  60
            + K+VV +GAG+SAESGI TFR  DGLWE +R+E+VATPE + +NP LVQ FYNERR+ +
Sbjct  42   LPKVVVLTGAGISAESGIKTFRSEDGLWEEHRVEDVATPEGYHRNPKLVQQFYNERRRQL  101

Query  61   L--AAQPNLAHQIIAQLESCY---QVQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSGP  115
               + QPN AH  +A+LE         ++TQNID+LHE+AGS H+LH+HG +   +    
Sbjct  102  QQPSIQPNEAHYALAKLEQYLGKDNFLLVTQNIDNLHEKAGSKHILHMHGELLKVRC---  158

Query  116  NAQFTQTFYPIDGWQLDLNQDK----CNEGYPLRPHVVWFGEAVPAYDDAIAMLKDADVF  171
              Q  Q F     W+ DL+       C    PLRPH+VWFGE     D+    L  AD+F
Sbjct  159  -PQSGQVF----EWKGDLSTTDYCHCCQFPSPLRPHIVWFGEMPIGMDEIYHALAQADLF  213

Query  172  IVIGSTLSVYPVAGLIHE  189
            I IG++ +VYP AG +HE
Sbjct  214  IAIGTSGNVYPAAGFVHE  231


>Q9KRX4 NAD-dependent protein deacylase [Vibrio cholerae serotype 
O1 (strain ATCC 39315 / El Tor Inaba N16961)]
Length=246

 Score = 168 bits (425),  Expect = 3e-55
 Identities = 92/196 (47%), Positives = 124/196 (63%), Gaps = 8/196 (4%)

Query  2    KKLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNIL  61
            + +V+ +GAG+SAESGI TFR  DGLWEN+RIE+VATPE +Q++P +V  FYN+RR+ +L
Sbjct  6    RHVVILTGAGISAESGIQTFRAQDGLWENHRIEDVATPEGFQRDPDMVLEFYNQRRRKLL  65

Query  62   --AAQPNLAHQIIAQLESCYQ--VQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSGPNA  117
              A QPN AH  + +LE   Q  V VITQNID+LHER GS +++H+HG +  A+    N 
Sbjct  66   SDAIQPNPAHLALGKLEKELQGSVTVITQNIDNLHERGGSQNIIHMHGELLKARCPESNQ  125

Query  118  QFTQTFYPIDGWQLDLNQDKCNEGYPLRPHVVWFGEAVPAYDDAIAMLKDADVFIVIGST  177
               Q      G   DL    C     +RPH+VWFGE      D  A L+ AD+F+ IG++
Sbjct  126  TVEQKEDIRHG---DLCH-CCQMPAQMRPHIVWFGEMPLRMGDIYAALEQADLFVSIGTS  181

Query  178  LSVYPVAGLIHEIPNH  193
              VYP AG +H+   H
Sbjct  182  GVVYPAAGFVHDARMH  197


>Q83RR8 NAD-dependent protein deacylase [Shigella flexneri]
Length=273

 Score = 168 bits (425),  Expect = 6e-55
 Identities = 93/199 (47%), Positives = 128/199 (64%), Gaps = 16/199 (8%)

Query  3    KLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNIL-  61
            +++V +GAG+SAESGI TFR  DGLWE +R+E+VATPE + ++P LVQ FYN RR+ +  
Sbjct  42   RVLVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQAFYNARRRQLQQ  101

Query  62   -AAQPNLAHQIIAQLESCY--QVQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSGPNAQ  118
               QPN AH  +A+L+     +  ++TQNID+LHERAG+T+V+H+HG +   + S     
Sbjct  102  PEIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCS-----  156

Query  119  FTQTFYPIDGWQLDLN-QDKCN---EGYPLRPHVVWFGEAVPAYDDAIAMLKDADVFIVI  174
              Q+   +D W  D+  +DKC+      PLRPHVVWFGE     D+    L  ADVFI I
Sbjct  157  --QSGQVLD-WTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADVFIAI  213

Query  175  GSTLSVYPVAGLIHEIPNH  193
            G++  VYP AG +HE   H
Sbjct  214  GTSGHVYPAAGFVHEAKLH  232


>Q8FIM4 NAD-dependent protein deacylase [Escherichia coli O6:H1 
(strain CFT073 / ATCC 700928 / UPEC)]
Length=273

 Score = 167 bits (424),  Expect = 8e-55
 Identities = 92/199 (46%), Positives = 128/199 (64%), Gaps = 16/199 (8%)

Query  3    KLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNIL-  61
            +++V +GAG+SAESGI TFR  DGLWE +R+E+VATPE + ++P LVQ FYN RR+ +  
Sbjct  42   RVLVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQTFYNARRRQLQQ  101

Query  62   -AAQPNLAHQIIAQLESCY--QVQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSGPNAQ  118
               QPN AH  +A+L+     +  ++TQNID+LHERAG+T+V+H+HG +   + S     
Sbjct  102  PEIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCS-----  156

Query  119  FTQTFYPIDGWQLDLN-QDKCN---EGYPLRPHVVWFGEAVPAYDDAIAMLKDADVFIVI  174
              Q+   +D W  D+  +DKC+      PLRPHVVWFGE     D+    L  AD+FI I
Sbjct  157  --QSGQVLD-WTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAI  213

Query  175  GSTLSVYPVAGLIHEIPNH  193
            G++  VYP AG +HE   H
Sbjct  214  GTSGHVYPAAGFVHEAKLH  232


>Q8X8E0 NAD-dependent protein deacylase [Escherichia coli O157:H7]
Length=273

 Score = 167 bits (424),  Expect = 8e-55
 Identities = 92/199 (46%), Positives = 128/199 (64%), Gaps = 16/199 (8%)

Query  3    KLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNIL-  61
            +++V +GAG+SAESGI TFR  DGLWE +R+E+VATPE + ++P LVQ FYN RR+ +  
Sbjct  42   RVLVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQAFYNARRRQLQQ  101

Query  62   -AAQPNLAHQIIAQLESCY--QVQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSGPNAQ  118
               QPN AH  +A+L+     +  ++TQNID+LHERAG+T+V+H+HG +   + S     
Sbjct  102  PEIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCS-----  156

Query  119  FTQTFYPIDGWQLDLN-QDKCN---EGYPLRPHVVWFGEAVPAYDDAIAMLKDADVFIVI  174
              Q+   +D W  D+  +DKC+      PLRPHVVWFGE     D+    L  AD+FI I
Sbjct  157  --QSGQVLD-WTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAI  213

Query  175  GSTLSVYPVAGLIHEIPNH  193
            G++  VYP AG +HE   H
Sbjct  214  GTSGHVYPAAGFVHEAKLH  232


>P75960 NAD-dependent protein deacylase [Escherichia coli (strain 
K12)]
Length=279

 Score = 167 bits (424),  Expect = 1e-54
 Identities = 92/199 (46%), Positives = 128/199 (64%), Gaps = 16/199 (8%)

Query  3    KLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNIL-  61
            +++V +GAG+SAESGI TFR  DGLWE +R+E+VATPE + ++P LVQ FYN RR+ +  
Sbjct  42   RVLVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQAFYNARRRQLQQ  101

Query  62   -AAQPNLAHQIIAQLESCY--QVQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSGPNAQ  118
               QPN AH  +A+L+     +  ++TQNID+LHERAG+T+V+H+HG +   + S     
Sbjct  102  PEIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCS-----  156

Query  119  FTQTFYPIDGWQLDLN-QDKCN---EGYPLRPHVVWFGEAVPAYDDAIAMLKDADVFIVI  174
              Q+   +D W  D+  +DKC+      PLRPHVVWFGE     D+    L  AD+FI I
Sbjct  157  --QSGQVLD-WTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAI  213

Query  175  GSTLSVYPVAGLIHEIPNH  193
            G++  VYP AG +HE   H
Sbjct  214  GTSGHVYPAAGFVHEAKLH  232


>Q584D5 NAD-dependent protein deacylase SIR2rp3 [Trypanosoma brucei 
brucei (strain 927/4 GUTat10.1)]
Length=244

 Score = 166 bits (419),  Expect = 2e-54
 Identities = 87/190 (46%), Positives = 127/190 (67%), Gaps = 10/190 (5%)

Query  4    LVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNILA-  62
            + + +GAG+SAESGI TFRD +GLWEN+R+E+V TP A+ + P++VQ FYNERR+ +L+ 
Sbjct  8    IAILTGAGISAESGISTFRDQNGLWENHRVEDVCTPAAFLKQPTVVQRFYNERRRALLSP  67

Query  63   -AQPNLAHQIIAQLESCY---QVQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSGPNAQ  118
              +PN +HQ +A+L+  Y   QV +ITQNIDDLHERAGS  VLH+HG +   + +     
Sbjct  68   EVKPNASHQALARLQREYKDGQVVIITQNIDDLHERAGSRQVLHMHGELLKVRCTATGRV  127

Query  119  FTQTFYPIDGWQLDLNQDKCNEGYPLRPHVVWFGEAVPAYDDAI-AMLKDADVFIVIGST  177
            F      I G   +   + C     LRPH+VWF E +P Y D I  ++++A +F+ +G++
Sbjct  128  FESREDVIHG---ESKCECCGVVETLRPHIVWFNE-MPLYMDVIDEVVQNAGLFVAVGTS  183

Query  178  LSVYPVAGLI  187
             +VYP AGL+
Sbjct  184  GNVYPAAGLV  193


>P0A2F2 NAD-dependent protein deacylase [Salmonella typhimurium 
(strain LT2 / SGSC1412 / ATCC 700720)]
Length=273

 Score = 166 bits (421),  Expect = 2e-54
 Identities = 91/199 (46%), Positives = 126/199 (63%), Gaps = 16/199 (8%)

Query  3    KLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNIL-  61
            +++V +GAG+SAESGI TFR  DGLWE +R+E+VATPE + +NP LVQ FYN RR+ +  
Sbjct  42   RVLVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFARNPGLVQTFYNARRQQLQQ  101

Query  62   -AAQPNLAHQIIAQLESCY--QVQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSGPNAQ  118
               QPN AH  +A+LE     +  ++TQNID+LHERAG+ +++H+HG +   + S  + Q
Sbjct  102  PEIQPNAAHLALAKLEEALGDRFLLVTQNIDNLHERAGNRNIIHMHGELLKVRCS-QSGQ  160

Query  119  FTQTFYPIDGWQLD-LNQDKCN---EGYPLRPHVVWFGEAVPAYDDAIAMLKDADVFIVI  174
              +       W  D + +DKC+      PLRPHVVWFGE     D+    L  AD+FI I
Sbjct  161  ILE-------WNGDVMPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAI  213

Query  175  GSTLSVYPVAGLIHEIPNH  193
            G++  VYP AG +HE   H
Sbjct  214  GTSGHVYPAAGFVHEAKLH  232


>O28597 NAD-dependent protein deacylase 1 [Archaeoglobus fulgidus 
(strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / 
VC-16)]
Length=245

 Score = 148 bits (374),  Expect = 1e-47
 Identities = 88/192 (46%), Positives = 117/192 (61%), Gaps = 15/192 (8%)

Query  2    KKLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNIL  61
            K LV  +GAG+SAESGI TFR  DGLW  YR EE+A P+A+ ++P  V  +Y  R + + 
Sbjct  13   KYLVALTGAGVSAESGIPTFRGKDGLWNRYRPEELANPQAFAKDPEKVWKWYAWRMEKVF  72

Query  62   AAQPNLAHQIIAQLESCYQVQ-VITQNIDDLHERAGSTHVLHLHGNIRLAKSSGPNAQF-  119
             AQPN AHQ  A+LE    ++ +ITQN+DDLHERAGS +V+HLHG++R+ + +  N  F 
Sbjct  73   NAQPNKAHQAFAELERLGVLKCLITQNVDDLHERAGSRNVIHLHGSLRVVRCTSCNNSFE  132

Query  120  ---TQTFYPIDGWQLDLNQDKCNEGYPLRPHVVWFGEAVP--AYDDAIAMLKDADVFIVI  174
                    P+         DKC  G  LRP VVWFGE +P    D A+  ++ ADV IV 
Sbjct  133  VESAPKIPPLP------KCDKC--GSLLRPGVVWFGEMLPPDVLDRAMREVERADVIIVA  184

Query  175  GSTLSVYPVAGL  186
            G++  V P A L
Sbjct  185  GTSAVVQPAASL  196


>A0R2N3 NAD-dependent protein deacylase Sir2 [Mycolicibacterium 
smegmatis (strain ATCC 700084 / mc(2)155)]
Length=240

 Score = 136 bits (342),  Expect = 6e-43
 Identities = 76/187 (41%), Positives = 110/187 (59%), Gaps = 3/187 (2%)

Query  3    KLVVFSGAGMSAESGIHTFRDHD-GLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNIL  61
            ++ V SGAG+SAESG+ TFRD + GLW      E+++ + WQ+NP  V  +Y  R   + 
Sbjct  2    QVTVLSGAGISAESGVPTFRDAETGLWAQVDPYEISSTDGWQRNPEKVWAWYLWRHYMMA  61

Query  62   AAQPNLAHQIIAQLESCYQVQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSGPNAQFTQ  121
               PN AH+ +A  E    V+V+TQNIDDLHERAGST+V HLHG++   +     + F  
Sbjct  62   RVAPNEAHRTVAAWEDHLDVRVVTQNIDDLHERAGSTNVYHLHGSLFEFRCDACGSAFEG  121

Query  122  TFYPIDGWQLDLNQDKCNEGYPLRPHVVWFGEAVP--AYDDAIAMLKDADVFIVIGSTLS  179
                +      ++   C     +RP VVWFGE +P  A++ ++  +  ADV IV+G++  
Sbjct  122  NLPEMPEPVETIDPPVCPCSGLIRPSVVWFGEPLPDAAWNRSVLAVSSADVVIVVGTSSI  181

Query  180  VYPVAGL  186
            VYP AGL
Sbjct  182  VYPAAGL  188


>P9WGG3 NAD-dependent protein deacylase [Mycobacterium tuberculosis 
(strain ATCC 25618 / H37Rv)]
Length=237

 Score = 133 bits (334),  Expect = 9e-42
 Identities = 72/187 (39%), Positives = 109/187 (58%), Gaps = 3/187 (2%)

Query  3    KLVVFSGAGMSAESGIHTFRDH-DGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNIL  61
            ++ V SGAG+SAESG+ TFRD  +GLW  +   E+++ + W +NP  V  +Y  R   + 
Sbjct  2    RVAVLSGAGISAESGVPTFRDDKNGLWARFDPYELSSTQGWLRNPERVWGWYLWRHYLVA  61

Query  62   AAQPNLAHQIIAQLESCYQVQVITQNIDDLHERAGSTHVLHLHGNIRLAKSSGPNAQFTQ  121
              +PN  H+ IA  +   +V VITQN+DDLHERAGS  V HLHG++   + +     +T 
Sbjct  62   NVEPNDGHRAIAAWQDHAEVSVITQNVDDLHERAGSGAVHHLHGSLFEFRCARCGVPYTD  121

Query  122  TFYPIDGWQLDLNQDKCNEGYPLRPHVVWFGEAVP--AYDDAIAMLKDADVFIVIGSTLS  179
                +    +++    C+ G  +RP +VWFGE +P   +  A+     ADV +V+G++  
Sbjct  122  ALPEMPEPAIEVEPPVCDCGGLIRPDIVWFGEPLPEEPWRSAVEATGSADVMVVVGTSAI  181

Query  180  VYPVAGL  186
            VYP AGL
Sbjct  182  VYPAAGL  188


>Q9JN05 NAD-dependent protein deacylase [Campylobacter jejuni 
subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)]
Length=233

 Score = 127 bits (318),  Expect = 2e-39
 Identities = 77/188 (41%), Positives = 108/188 (57%), Gaps = 13/188 (7%)

Query  1    MKKLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNI  60
            MK +++ SGAG+SA SG+ TFRD+DGLWE Y + EV +   +++NP  V  FY+ RR  +
Sbjct  1    MKNIMILSGAGLSAPSGLKTFRDNDGLWEEYDVMEVCSATGFRKNPKKVLDFYDARRAQL  60

Query  61   LAAQPNLAHQIIAQLESCY--QVQVITQNIDDLHERAGSTHVLHLHG---NIRLAKSSGP  115
               +PN AH+ IAQL+  +   + VITQN+DDL ERAG   V+HLHG    +R  K  G 
Sbjct  61   QNVKPNHAHEKIAQLKEKWGKNLFVITQNVDDLLERAGCKDVVHLHGFLPELRCLKCEGI  120

Query  116  NAQFTQTFYPIDGWQLDLNQDKCNEGYPLRPHVVWFGEAVPAYDDAIAMLKDADVFIVIG  175
                 + F        D    KC +   LR ++V F E  PAY    ++L    +FI IG
Sbjct  121  FNIGYEKF-------TDKQCPKC-KSKDLRHNIVMFEEQAPAYATLYSLLHQTSLFISIG  172

Query  176  STLSVYPV  183
            ++ +V PV
Sbjct  173  TSGAVLPV  180


>O30124 NAD-dependent protein deacylase 2 [Archaeoglobus fulgidus 
(strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / 
VC-16)]
Length=253

 Score = 126 bits (317),  Expect = 4e-39
 Identities = 82/188 (44%), Positives = 111/188 (59%), Gaps = 4/188 (2%)

Query  2    KKLVVFSGAGMSAESGIHTFRDHDGLWENYRIEEVATPEAWQQNPSLVQHFYNERRKNIL  61
            K  VVF+GAG+SAESGI TFR  DGLW  Y  EEVA+   +++NP     F  E  K+ L
Sbjct  16   KHAVVFTGAGISAESGIPTFRGEDGLWRKYDPEEVASISGFKRNPRAFWEFSME-MKDKL  74

Query  62   AAQPNLAHQIIAQLESCYQVQ-VITQNIDDLHERAGSTHVLHLHGNIRLAKSSGPNAQFT  120
             A+PN AH  IA+LE    V+ VITQNID LH+RAGS  VL LHG++        +  + 
Sbjct  75   FAEPNPAHYAIAELERMGIVKAVITQNIDMLHQRAGSRRVLELHGSMDKLDCLDCHETYD  134

Query  121  QTFYPIDGWQLDLNQDKCNEGYPLRPHVVWFGEAVP--AYDDAIAMLKDADVFIVIGSTL  178
             + +  D  + ++ + +    Y ++P VV FGE +P     +AI   K  D F+V+GS+L
Sbjct  135  WSEFVEDFNKGEIPRCRKCGSYYVKPRVVLFGEPLPQRTLFEAIEEAKHCDAFMVVGSSL  194

Query  179  SVYPVAGL  186
             VYP A L
Sbjct  195  VVYPAAEL  202



Lambda      K        H        a         alpha
   0.323    0.137    0.429    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 763618


  Database: 24e56caba3610cbc1bd6b4e60516abc1.SwissProt.fasta
    Posted date:  May 20, 2024  7:01 PM
  Number of letters in database: 4,815
  Number of sequences in database:  19



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40