BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 4e2ee410b49d944265c4e1b512211c09.SwissProt.fasta
17 sequences; 8,791 total letters
Query= ACIAD1717
Length=393
Score E
Sequences producing significant alignments: (Bits) Value
P77234 Sel1-repeat-containing protein YbeQ [Escherichia coli (str... 96.3 2e-25
A0A0H2VDN9 Secretory immunoglobulin A-binding protein EsiB [Esche... 86.7 1e-21
Q10NT7 ERAD-associated E3 ubiquitin-protein ligase component HRD3... 81.6 8e-20
Q9ESM7 Protein sel-1 homolog 1 [Mesocricetus auratus] 79.7 4e-19
Q9Z2G6 Protein sel-1 homolog 1 [Mus musculus] 79.3 5e-19
Q80Z70 Protein sel-1 homolog 1 [Rattus norvegicus] 79.3 5e-19
Q9UBV2 Protein sel-1 homolog 1 [Homo sapiens] 79.3 5e-19
Q9LM25 ERAD-associated E3 ubiquitin-protein ligase component HRD3... 78.2 1e-18
Q5UP92 Putative sel1-like repeat-containing protein L18 [Acantham... 77.4 2e-18
Q9ZKB5 Putative beta-lactamase HcpC [Helicobacter pylori (strain ... 73.9 7e-18
O25728 Putative beta-lactamase HcpC [Helicobacter pylori (strain ... 73.9 7e-18
Q5TEA6 Protein sel-1 homolog 2 [Homo sapiens] 73.2 5e-17
P77296 Sel1-repeat-containing protein YbeT [Escherichia coli (str... 65.9 8e-16
O24968 Putative beta-lactamase HcpD [Helicobacter pylori (strain ... 65.9 4e-15
O25021 Putative beta-lactamase HcpE [Helicobacter pylori (strain ... 63.9 2e-14
O25001 Beta-lactamase HcpA [Helicobacter pylori (strain ATCC 7003... 58.5 7e-13
J9VSG5 Chitin synthase regulator 2 [Cryptococcus neoformans var. ... 58.2 2e-12
>P77234 Sel1-repeat-containing protein YbeQ [Escherichia coli
(strain K12)]
Length=325
Score = 96.3 bits (238), Expect = 2e-25
Identities = 51/163 (31%), Positives = 85/163 (52%), Gaps = 0/163 (0%)
Query 228 AQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEK 287
A +G AQN LA +Y +G V QN +LA FWY K+A Q + + + Y G G+++
Sbjct 163 ALQGHSDAQNNLADLYEDGKGVAQNKTLAAFWYLKSAQQGNRHAQFQIAWDYNAGEGVDQ 222
Query 288 NYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRL 347
+Y+ + W K+ Q AY + +Y+ G V+KD Q A ++ KAA AT+ Y L
Sbjct 223 DYKQAMYWYLKAAAQGSVGAYVNIGYMYKHGQGVEKDYQAAFEWFTKAAECNDATAWYNL 282
Query 348 GQIFELGQGVTLDLKLAKRFYHQAASNFSSEAKNRLDILDQLI 390
++ G+G +DL+ A Y + S+ + + + + L+
Sbjct 283 AIMYHYGEGRPVDLRQALDLYRKVQSSGTRDVSQEIRETEDLL 325
Score = 94.7 bits (234), Expect = 7e-25
Identities = 58/174 (33%), Positives = 89/174 (51%), Gaps = 4/174 (2%)
Query 217 DIPNFKRTLK----QAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGE 272
+ PN+K + A+ G AQN L MY NG V ++ +LA FWY++ A Q + +
Sbjct 112 EAPNYKEAVVWYQIAAESGMSYAQNNLGWMYRNGNGVAKDYALAFFWYKQAALQGHSDAQ 171
Query 273 LNLGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFY 332
NL LY +G G+ +N L W KS +Q A F +A Y G V +D +QA+ +Y
Sbjct 172 NNLADLYEDGKGVAQNKTLAAFWYLKSAQQGNRHAQFQIAWDYNAGEGVDQDYKQAMYWY 231
Query 333 KKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAASNFSSEAKNRLDIL 386
KAA + +G +++ GQGV D + A ++ +AA + A L I+
Sbjct 232 LKAAAQGSVGAYVNIGYMYKHGQGVEKDYQAAFEWFTKAAECNDATAWYNLAIM 285
Score = 77.8 bits (190), Expect = 5e-19
Identities = 41/110 (37%), Positives = 62/110 (56%), Gaps = 0/110 (0%)
Query 225 LKQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLG 284
LK AQ+G AQ Q+A Y G V Q+ A++WY K A+Q +N+G +Y +G G
Sbjct 196 LKSAQQGNRHAQFQIAWDYNAGEGVDQDYKQAMYWYLKAAAQGSVGAYVNIGYMYKHGQG 255
Query 285 IEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKK 334
+EK+Y+ W K+ + N A++ LA +Y G D++QAL Y+K
Sbjct 256 VEKDYQAAFEWFTKAAECNDATAWYNLAIMYHYGEGRPVDLRQALDLYRK 305
Score = 61.6 bits (148), Expect = 1e-13
Identities = 50/188 (27%), Positives = 81/188 (43%), Gaps = 8/188 (4%)
Query 193 QYHLGFDIIDSDYNTSQSLIINCEDIPNFKRTLKQAQEGCIKAQNQLASMYLNGLDVTQN 252
QY +GF Y S I + +D F A++G +AQ L Y ++
Sbjct 28 QYIVGF------YYNRDSAIDSPDDEKAFYWLKLAAEQGHCEAQYSLGQKYTEDKSRHKD 81
Query 253 MSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTLA 312
A+FW +K A Q LG + G NY+ + W + + + A L
Sbjct 82 NEQAIFWLKKAALQGHTFASNALG--WTLDRGEAPNYKEAVVWYQIAAESGMSYAQNNLG 139
Query 313 ELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAA 372
+Y G+ V KD A +YK+AA H+ + L ++E G+GV + LA +Y ++A
Sbjct 140 WMYRNGNGVAKDYALAFFWYKQAALQGHSDAQNNLADLYEDGKGVAQNKTLAAFWYLKSA 199
Query 373 SNFSSEAK 380
+ A+
Sbjct 200 QQGNRHAQ 207
>A0A0H2VDN9 Secretory immunoglobulin A-binding protein EsiB [Escherichia
coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)]
Length=490
Score = 86.7 bits (213), Expect = 1e-21
Identities = 46/164 (28%), Positives = 87/164 (53%), Gaps = 0/164 (0%)
Query 220 NFKRTLKQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLY 279
N ++ ++A+ G KAQ +L Y G + T++++ A+ W+ + A Q E LG Y
Sbjct 26 NLEQLKQKAESGEAKAQLELGYRYFQGNETTKDLTQAMDWFRRAAEQGYTPAEYVLGLRY 85
Query 280 LNGLGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLR 339
+NG G+ ++Y + W KK+ + P A L +Y +G+ V+ D +++ +++ AA
Sbjct 86 MNGEGVPQDYAQAVIWYKKAALKGLPQAQQNLGVMYHEGNGVKVDKAESVKWFRLAAEQG 145
Query 340 HATSAYRLGQIFELGQGVTLDLKLAKRFYHQAASNFSSEAKNRL 383
+ +G + G GVT D +A+ +Y +AA + + N+L
Sbjct 146 RDSGQQSMGDAYFEGDGVTRDYVMAREWYSKAAEQGNVWSCNQL 189
Score = 84.3 bits (207), Expect = 8e-21
Identities = 60/196 (31%), Positives = 95/196 (48%), Gaps = 13/196 (7%)
Query 191 VLQYHLGFDIIDSDYNTSQSLIINCEDIPNFKRTLKQAQEGCIKAQNQLASMYLNGLD-V 249
+ Q+ LG Y Q L E + + K A++G Q LA +Y G + V
Sbjct 256 IAQFRLG-------YILEQGLAGAKEPLKALEWYRKSAEQGNSDGQYYLAHLYDKGAEGV 308
Query 250 TQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYF 309
+N A+ WY K+A Q D + NLG +Y LG E+ ++ + W +K+ + A F
Sbjct 309 AKNREQAISWYTKSAEQGDATAQANLGAIYFR-LGSEEEHKKAVEWFRKAAAKGEKAAQF 367
Query 310 TLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYH 369
L +G V+KD QQA I+ +KAA + + +LG+I+ G GV D A ++
Sbjct 368 NLGNALLQGKGVKKDEQQAAIWMRKAAEQGLSAAQVQLGEIYYYGLGVERDYVQAWAWFD 427
Query 370 QAASN----FSSEAKN 381
A++N F +E +N
Sbjct 428 TASTNDMNLFGTENRN 443
Score = 80.9 bits (198), Expect = 1e-19
Identities = 47/159 (30%), Positives = 86/159 (54%), Gaps = 1/159 (1%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
K A++G + + NQL MY GL V +N +++ WY K+A+ D G+L+L +Y G+G+
Sbjct 176 KAAEQGNVWSCNQLGYMYSRGLGVERNDAISAQWYRKSATSGDELGQLHLADMYYFGIGV 235
Query 286 EKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAY 345
++Y +S +Q A F L + E+G K+ +AL +Y+K+A ++ Y
Sbjct 236 TQDYTQSRVLFSQSAEQGNSIAQFRLGYILEQGLAGAKEPLKALEWYRKSAEQGNSDGQY 295
Query 346 RLGQIFELG-QGVTLDLKLAKRFYHQAASNFSSEAKNRL 383
L +++ G +GV + + A +Y ++A + A+ L
Sbjct 296 YLAHLYDKGAEGVAKNREQAISWYTKSAEQGDATAQANL 334
Score = 75.9 bits (185), Expect = 5e-18
Identities = 40/149 (27%), Positives = 79/149 (53%), Gaps = 0/149 (0%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
+ A++G A+ L Y+NG V Q+ + A+ WY+K A + P+ + NLG +Y G G+
Sbjct 68 RAAEQGYTPAEYVLGLRYMNGEGVPQDYAQAVIWYKKAALKGLPQAQQNLGVMYHEGNGV 127
Query 286 EKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAY 345
+ + + W + + +Q ++ + Y +G V +D A +Y KAA + S
Sbjct 128 KVDKAESVKWFRLAAEQGRDSGQQSMGDAYFEGDGVTRDYVMAREWYSKAAEQGNVWSCN 187
Query 346 RLGQIFELGQGVTLDLKLAKRFYHQAASN 374
+LG ++ G GV + ++ ++Y ++A++
Sbjct 188 QLGYMYSRGLGVERNDAISAQWYRKSATS 216
Score = 72.8 bits (177), Expect = 5e-17
Identities = 42/153 (27%), Positives = 73/153 (48%), Gaps = 0/153 (0%)
Query 228 AQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEK 287
A++G Q + Y G VT++ +A WY K A Q + LG +Y GLG+E+
Sbjct 142 AEQGRDSGQQSMGDAYFEGDGVTRDYVMAREWYSKAAEQGNVWSCNQLGYMYSRGLGVER 201
Query 288 NYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRL 347
N + W +KS LA++Y G V +D Q+ + + ++A ++ + +RL
Sbjct 202 NDAISAQWYRKSATSGDELGQLHLADMYYFGIGVTQDYTQSRVLFSQSAEQGNSIAQFRL 261
Query 348 GQIFELGQGVTLDLKLAKRFYHQAASNFSSEAK 380
G I E G + A +Y ++A +S+ +
Sbjct 262 GYILEQGLAGAKEPLKALEWYRKSAEQGNSDGQ 294
Score = 67.8 bits (164), Expect = 2e-15
Identities = 44/164 (27%), Positives = 79/164 (48%), Gaps = 1/164 (1%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
K A +G +AQ L MY G V + + ++ W+ A Q G+ ++G Y G G+
Sbjct 104 KAALKGLPQAQQNLGVMYHEGNGVKVDKAESVKWFRLAAEQGRDSGQQSMGDAYFEGDGV 163
Query 286 EKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAY 345
++Y + W K+ +Q + L +Y +G V+++ + +Y+K+A
Sbjct 164 TRDYVMAREWYSKAAEQGNVWSCNQLGYMYSRGLGVERNDAISAQWYRKSATSGDELGQL 223
Query 346 RLGQIFELGQGVTLDLKLAKRFYHQAASNFSSEAKNRLD-ILDQ 388
L ++ G GVT D ++ + Q+A +S A+ RL IL+Q
Sbjct 224 HLADMYYFGIGVTQDYTQSRVLFSQSAEQGNSIAQFRLGYILEQ 267
Score = 62.4 bits (150), Expect = 1e-13
Identities = 46/159 (29%), Positives = 79/159 (50%), Gaps = 2/159 (1%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGL-G 284
+ A++G AQ +L + GL + AL WY K+A Q + +G+ L LY G G
Sbjct 248 QSAEQGNSIAQFRLGYILEQGLAGAKEPLKALEWYRKSAEQGNSDGQYYLAHLYDKGAEG 307
Query 285 IEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSA 344
+ KN E ++W KS +Q A L +Y + +++ ++A+ +++KAA +
Sbjct 308 VAKNREQAISWYTKSAEQGDATAQANLGAIYFRLGS-EEEHKKAVEWFRKAAAKGEKAAQ 366
Query 345 YRLGQIFELGQGVTLDLKLAKRFYHQAASNFSSEAKNRL 383
+ LG G+GV D + A + +AA S A+ +L
Sbjct 367 FNLGNALLQGKGVKKDEQQAAIWMRKAAEQGLSAAQVQL 405
Score = 41.6 bits (96), Expect = 4e-07
Identities = 25/96 (26%), Positives = 47/96 (49%), Gaps = 0/96 (0%)
Query 291 LGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQI 350
+ L +K+ + A L Y +G+ KD+ QA+ ++++AA + + Y LG
Sbjct 25 VNLEQLKQKAESGEAKAQLELGYRYFQGNETTKDLTQAMDWFRRAAEQGYTPAEYVLGLR 84
Query 351 FELGQGVTLDLKLAKRFYHQAASNFSSEAKNRLDIL 386
+ G+GV D A +Y +AA +A+ L ++
Sbjct 85 YMNGEGVPQDYAQAVIWYKKAALKGLPQAQQNLGVM 120
>Q10NT7 ERAD-associated E3 ubiquitin-protein ligase component
HRD3 [Oryza sativa subsp. japonica]
Length=694
Score = 81.6 bits (200), Expect = 8e-20
Identities = 51/160 (32%), Positives = 81/160 (51%), Gaps = 2/160 (1%)
Query 216 EDIPNFKRTLKQAQEGCIKAQNQLASMYLNGL-DVTQNMSLALFWYEKTASQNDPEGELN 274
ED +F+ T QAQ G A ++L +Y GL V ++ A W+ K + D
Sbjct 256 EDDEDFQITEYQAQRGNTVAMHKLGLLYYYGLRGVRRDYGKAYHWFSKAVEKGDTRAMEL 315
Query 275 LGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGH-IVQKDIQQALIFYK 333
LG++Y G G+E+NY W+ + KQ AY L LY KG+ + +K++ +A F++
Sbjct 316 LGEIYARGAGVERNYTEAYKWLTLAAKQQQYSAYNGLGYLYVKGYGVEKKNLTKAKEFFE 375
Query 334 KAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAAS 373
AA + Y LG ++ G GV D+ A F+ +A +
Sbjct 376 IAAEHKEHGGYYNLGVLYLKGIGVKRDVMTACNFFLRAVN 415
Score = 65.5 bits (158), Expect = 1e-14
Identities = 43/155 (28%), Positives = 79/155 (51%), Gaps = 11/155 (7%)
Query 228 AQEGCIKAQNQLASMYLNGLDVTQ-NMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIE 286
A++ A N L +Y+ G V + N++ A ++E A + G NLG LYL G+G++
Sbjct 341 AKQQQYSAYNGLGYLYVKGYGVEKKNLTKAKEFFEIAAEHKEHGGYYNLGVLYLKGIGVK 400
Query 287 KNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAAN-------LR 339
++ + ++V P A + +A+L++KG +++++Q A + YK A R
Sbjct 401 RDVMTACNFFLRAVNAGQPKAIYQVAKLFQKGVGLKRNLQMAAVMYKSVAERGPWSSLSR 460
Query 340 HATSAYRLGQIFELGQGVTLDLKLAKRFYHQAASN 374
A +Y G ++G+ + L ++A Y A SN
Sbjct 461 WALESYLKG---DIGKALLLYSRMADLGYEVAQSN 492
Score = 46.6 bits (109), Expect = 1e-08
Identities = 28/87 (32%), Positives = 45/87 (52%), Gaps = 1/87 (1%)
Query 285 IEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSA 344
+E++ W + S +Q A + + Y G V +D ++A Y A + +A +
Sbjct 516 MERHLRAHALWWQAS-EQGNEHAALLIGDAYYYGRGVGRDYERAAEAYMHAQSQSNAQAM 574
Query 345 YRLGQIFELGQGVTLDLKLAKRFYHQA 371
+ LG + E G G+ LDL LAKR+Y QA
Sbjct 575 FNLGYMHEHGHGLPLDLHLAKRYYDQA 601
Score = 38.9 bits (89), Expect = 4e-06
Identities = 22/83 (27%), Positives = 39/83 (47%), Gaps = 2/83 (2%)
Query 256 ALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTLAELY 315
AL+W + + Q + L +G Y G G+ ++YE + Q+ A F L ++
Sbjct 524 ALWW--QASEQGNEHAALLIGDAYYYGRGVGRDYERAAEAYMHAQSQSNAQAMFNLGYMH 581
Query 316 EKGHIVQKDIQQALIFYKKAANL 338
E GH + D+ A +Y +A +
Sbjct 582 EHGHGLPLDLHLAKRYYDQAVEV 604
Score = 25.0 bits (53), Expect = 0.074
Identities = 18/66 (27%), Positives = 29/66 (44%), Gaps = 0/66 (0%)
Query 321 VQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAASNFSSEAK 380
V++D +A ++ KA + LG+I+ G GV + A ++ AA A
Sbjct 290 VRRDYGKAYHWFSKAVEKGDTRAMELLGEIYARGAGVERNYTEAYKWLTLAAKQQQYSAY 349
Query 381 NRLDIL 386
N L L
Sbjct 350 NGLGYL 355
>Q9ESM7 Protein sel-1 homolog 1 [Mesocricetus auratus]
Length=794
Score = 79.7 bits (195), Expect = 4e-19
Identities = 45/131 (34%), Positives = 68/131 (52%), Gaps = 1/131 (1%)
Query 228 AQEGCIKAQNQLASMYLNGLDVT-QNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIE 286
A G A L MY G D+ Q+ AL +++K A +P G+ LG YL G GI+
Sbjct 405 ANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGIQ 464
Query 287 KNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYR 346
NY+L L + +K+ +Q + D L +Y G V++D +QAL ++ A+ H + Y
Sbjct 465 VNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYN 524
Query 347 LGQIFELGQGV 357
L Q+ G GV
Sbjct 525 LAQMHASGTGV 535
Score = 65.9 bits (159), Expect = 1e-14
Identities = 44/156 (28%), Positives = 77/156 (49%), Gaps = 10/156 (6%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
K A G Q+ L YL G + N LAL +++K A Q +G+L LG +Y NG+G+
Sbjct 440 KAADMGNPVGQSGLGMAYLYGRGIQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGV 499
Query 286 EKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKK-------AANL 338
+++Y+ L + + + + A++ LA+++ G V + A+ +K + L
Sbjct 500 KRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERL 559
Query 339 RHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAASN 374
A ++Y+ G + V L LA++ Y A SN
Sbjct 560 MTAYNSYKDG---DYNAAVVQYLLLAEQGYEVAQSN 592
Score = 55.8 bits (133), Expect = 2e-11
Identities = 44/159 (28%), Positives = 76/159 (48%), Gaps = 4/159 (3%)
Query 216 EDIPNFKRTLKQAQEGCIKAQNQLASMYLNG-LDVTQNMSLALFWYEKTASQNDPEGELN 274
ED+ + + L A++G ++AQ L ++L+G V QN A ++ A+ +
Sbjct 358 EDLIQYYQFL--AEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAF 415
Query 275 LGKLYLNGLGI-EKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYK 333
LGK+Y G I ++ E L + KK+ P L Y G +Q + AL +++
Sbjct 416 LGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGIQVNYDLALKYFQ 475
Query 334 KAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAA 372
KAA +LG ++ G GV D K A ++++ A+
Sbjct 476 KAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLAS 514
Score = 48.9 bits (115), Expect = 3e-09
Identities = 29/91 (32%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query 283 LGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHAT 342
+G + Y L ++ Q Y A L + + G D + A I Y+ A+ +H+
Sbjct 605 VGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSA 664
Query 343 SA-YRLGQIFELGQGVTLDLKLAKRFYHQAA 372
A + LG + E G G+ D+ LAKRFY AA
Sbjct 665 QAMFNLGYMHEKGLGIKQDIHLAKRFYDMAA 695
Score = 45.1 bits (105), Expect = 4e-08
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 7/144 (5%)
Query 194 YHLGFDIIDSDYNTSQSLIINCEDIPNFKRTLKQAQEGCIKAQNQLASMYLNGLDVTQNM 253
Y G I++ SQ ++ K A KA +++ L G +TQN+
Sbjct 187 YQAGMKILNGSNRKSQKR-------EAYRYLQKAAGMNHTKALERVSYALLFGDYLTQNI 239
Query 254 SLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTLAE 313
A +EK + P+G+ LG LY++GLG+ + L + A+ L
Sbjct 240 QAAKEMFEKLTEEGSPKGQTALGFLYVSGLGVNSSQAKALVYYTFGALGGNLIAHMVLGY 299
Query 314 LYEKGHIVQKDIQQALIFYKKAAN 337
Y G V + + L Y+ AN
Sbjct 300 RYWAGIGVLQSCESVLTHYRLVAN 323
Score = 41.6 bits (96), Expect = 5e-07
Identities = 26/82 (32%), Positives = 40/82 (49%), Gaps = 1/82 (1%)
Query 256 ALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIK-KSVKQNYPDAYFTLAEL 314
AL + + ASQ + LG + G G + +YE + S +Q+ A F L +
Sbjct 614 ALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYM 673
Query 315 YEKGHIVQKDIQQALIFYKKAA 336
+EKG +++DI A FY AA
Sbjct 674 HEKGLGIKQDIHLAKRFYDMAA 695
Score = 32.3 bits (72), Expect = 4e-04
Identities = 40/199 (20%), Positives = 73/199 (37%), Gaps = 47/199 (24%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
K +EG K Q L +Y++GL V + + AL +Y A + + LG Y G+G+
Sbjct 248 KLTEEGSPKGQTALGFLYVSGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGV 307
Query 286 EKNYELGLTWIKKSVKQNYPDAYFT---------------------------LAELY--- 315
++ E LT + D T L + Y
Sbjct 308 LQSCESVLTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFL 367
Query 316 -EKGHI----------------VQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVT 358
EKG + V+++ Q+A ++ AAN ++ + LG+++ G +
Sbjct 368 AEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIV 427
Query 359 LDLKLAKRFYHQAASNFSS 377
Y + A++ +
Sbjct 428 PQSNETALHYFKKAADMGN 446
Score = 21.9 bits (45), Expect = 0.68
Identities = 32/166 (19%), Positives = 62/166 (37%), Gaps = 28/166 (17%)
Query 124 CEKSWLNFTIFYERESYTDGSYKIERYEIPDLNDESNPDIQYHKYYYIIEKSLSFY--HH 181
CE+ + + SY DG Y + L ++ Q + + + ++ + +
Sbjct 550 CERGRWSERLMTAYNSYKDGDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGENE 609
Query 182 YLARALL--------------VEVLQYHLGFDIIDSDYNTSQSLIINCEDIPNFKRTLKQ 227
RALL +++ YH D DY T+ L
Sbjct 610 TYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETA-----------FIHYRLAS 658
Query 228 AQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGEL 273
Q+ +A L M+ GL + Q++ LA +Y+ A++ P+ ++
Sbjct 659 EQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYD-MAAEASPDAQV 703
>Q9Z2G6 Protein sel-1 homolog 1 [Mus musculus]
Length=790
Score = 79.3 bits (194), Expect = 5e-19
Identities = 44/131 (34%), Positives = 68/131 (52%), Gaps = 1/131 (1%)
Query 228 AQEGCIKAQNQLASMYLNGLDVT-QNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIE 286
A G A L MY G D+ Q+ AL +++K A +P G+ LG YL G G++
Sbjct 401 ANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQ 460
Query 287 KNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYR 346
NY+L L + +K+ +Q + D L +Y G V++D +QAL ++ A+ H + Y
Sbjct 461 VNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYN 520
Query 347 LGQIFELGQGV 357
L Q+ G GV
Sbjct 521 LAQMHASGTGV 531
Score = 65.9 bits (159), Expect = 1e-14
Identities = 43/153 (28%), Positives = 73/153 (48%), Gaps = 4/153 (3%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
K A G Q+ L YL G V N LAL +++K A Q +G+L LG +Y NG+G+
Sbjct 436 KAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGV 495
Query 286 EKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAAN----LRHA 341
+++Y+ L + + + + A++ LA+++ G V + A+ +K
Sbjct 496 KRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERL 555
Query 342 TSAYRLGQIFELGQGVTLDLKLAKRFYHQAASN 374
+AY + + V L LA++ Y A SN
Sbjct 556 MTAYNSYKDEDYNAAVVQYLLLAEQGYEVAQSN 588
Score = 56.2 bits (134), Expect = 1e-11
Identities = 45/159 (28%), Positives = 76/159 (48%), Gaps = 4/159 (3%)
Query 216 EDIPNFKRTLKQAQEGCIKAQNQLASMYLNG-LDVTQNMSLALFWYEKTASQNDPEGELN 274
ED+ + + L A++G ++AQ L ++L+G V QN A ++ A+ +
Sbjct 354 EDLIQYYQFL--AEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAF 411
Query 275 LGKLYLNGLGI-EKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYK 333
LGK+Y G I ++ E L + KK+ P L Y G VQ + AL +++
Sbjct 412 LGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQ 471
Query 334 KAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAA 372
KAA +LG ++ G GV D K A ++++ A+
Sbjct 472 KAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLAS 510
Score = 48.9 bits (115), Expect = 3e-09
Identities = 29/91 (32%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query 283 LGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHAT 342
+G + Y L ++ Q Y A L + + G D + A I Y+ A+ +H+
Sbjct 601 VGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSA 660
Query 343 SA-YRLGQIFELGQGVTLDLKLAKRFYHQAA 372
A + LG + E G G+ D+ LAKRFY AA
Sbjct 661 QAMFNLGYMHEKGLGIKQDIHLAKRFYDMAA 691
Score = 46.2 bits (108), Expect = 2e-08
Identities = 37/144 (26%), Positives = 58/144 (40%), Gaps = 7/144 (5%)
Query 194 YHLGFDIIDSDYNTSQSLIINCEDIPNFKRTLKQAQEGCIKAQNQLASMYLNGLDVTQNM 253
Y G I++ SQ ++ K A KA +++ L G +TQN+
Sbjct 183 YQAGMKILNGSNRKSQKR-------EAYRYLQKAAGMNHTKALERVSYALLFGDYLTQNI 235
Query 254 SLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTLAE 313
A +EK + P+G+ LG LY +GLG+ + L + A+ L
Sbjct 236 QAAKEMFEKLTEEGSPKGQTGLGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMILGY 295
Query 314 LYEKGHIVQKDIQQALIFYKKAAN 337
Y G V + + AL Y+ AN
Sbjct 296 RYWAGIGVLQSCESALTHYRLVAN 319
Score = 41.6 bits (96), Expect = 5e-07
Identities = 26/82 (32%), Positives = 40/82 (49%), Gaps = 1/82 (1%)
Query 256 ALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIK-KSVKQNYPDAYFTLAEL 314
AL + + ASQ + LG + G G + +YE + S +Q+ A F L +
Sbjct 610 ALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYM 669
Query 315 YEKGHIVQKDIQQALIFYKKAA 336
+EKG +++DI A FY AA
Sbjct 670 HEKGLGIKQDIHLAKRFYDMAA 691
Score = 32.3 bits (72), Expect = 4e-04
Identities = 40/199 (20%), Positives = 72/199 (36%), Gaps = 47/199 (24%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
K +EG K Q L +Y +GL V + + AL +Y A + + LG Y G+G+
Sbjct 244 KLTEEGSPKGQTGLGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMILGYRYWAGIGV 303
Query 286 EKNYELGLTWIKKSVKQNYPDAYFT---------------------------LAELY--- 315
++ E LT + D T L + Y
Sbjct 304 LQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFL 363
Query 316 -EKGHI----------------VQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVT 358
EKG + V+++ Q+A ++ AAN ++ + LG+++ G +
Sbjct 364 AEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIV 423
Query 359 LDLKLAKRFYHQAASNFSS 377
Y + A++ +
Sbjct 424 PQSNETALHYFKKAADMGN 442
>Q80Z70 Protein sel-1 homolog 1 [Rattus norvegicus]
Length=794
Score = 79.3 bits (194), Expect = 5e-19
Identities = 44/131 (34%), Positives = 68/131 (52%), Gaps = 1/131 (1%)
Query 228 AQEGCIKAQNQLASMYLNGLDVT-QNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIE 286
A G A L MY G D+ Q+ AL +++K A +P G+ LG YL G G++
Sbjct 405 ANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQ 464
Query 287 KNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYR 346
NY+L L + +K+ +Q + D L +Y G V++D +QAL ++ A+ H + Y
Sbjct 465 VNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYN 524
Query 347 LGQIFELGQGV 357
L Q+ G GV
Sbjct 525 LAQMHASGTGV 535
Score = 65.9 bits (159), Expect = 1e-14
Identities = 43/153 (28%), Positives = 73/153 (48%), Gaps = 4/153 (3%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
K A G Q+ L YL G V N LAL +++K A Q +G+L LG +Y NG+G+
Sbjct 440 KAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGV 499
Query 286 EKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAAN----LRHA 341
+++Y+ L + + + + A++ LA+++ G V + A+ +K
Sbjct 500 KRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERL 559
Query 342 TSAYRLGQIFELGQGVTLDLKLAKRFYHQAASN 374
+AY + + V L LA++ Y A SN
Sbjct 560 MTAYNSYKDDDYNAAVVQYLLLAEQGYEVAQSN 592
Score = 56.2 bits (134), Expect = 1e-11
Identities = 45/159 (28%), Positives = 76/159 (48%), Gaps = 4/159 (3%)
Query 216 EDIPNFKRTLKQAQEGCIKAQNQLASMYLNG-LDVTQNMSLALFWYEKTASQNDPEGELN 274
ED+ + + L A++G ++AQ L ++L+G V QN A ++ A+ +
Sbjct 358 EDLIQYYQFL--AEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAF 415
Query 275 LGKLYLNGLGI-EKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYK 333
LGK+Y G I ++ E L + KK+ P L Y G VQ + AL +++
Sbjct 416 LGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQ 475
Query 334 KAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAA 372
KAA +LG ++ G GV D K A ++++ A+
Sbjct 476 KAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLAS 514
Score = 48.9 bits (115), Expect = 3e-09
Identities = 29/91 (32%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query 283 LGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHAT 342
+G + Y L ++ Q Y A L + + G D + A I Y+ A+ +H+
Sbjct 605 VGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSA 664
Query 343 SA-YRLGQIFELGQGVTLDLKLAKRFYHQAA 372
A + LG + E G G+ D+ LAKRFY AA
Sbjct 665 QAMFNLGYMHEKGLGIKQDIHLAKRFYDMAA 695
Score = 46.2 bits (108), Expect = 2e-08
Identities = 30/104 (29%), Positives = 47/104 (45%), Gaps = 0/104 (0%)
Query 234 KAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGL 293
KA +++ L G +TQN+ A +EK + P+G+ LG LY +GLG+ + L
Sbjct 220 KALERVSYALLFGDYLTQNIQAAKEMFEKLTEEGSPKGQTGLGFLYASGLGVNSSQAKAL 279
Query 294 TWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAAN 337
+ A+ L Y G V + + AL Y+ AN
Sbjct 280 VYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVAN 323
Score = 41.6 bits (96), Expect = 5e-07
Identities = 26/82 (32%), Positives = 40/82 (49%), Gaps = 1/82 (1%)
Query 256 ALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIK-KSVKQNYPDAYFTLAEL 314
AL + + ASQ + LG + G G + +YE + S +Q+ A F L +
Sbjct 614 ALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYM 673
Query 315 YEKGHIVQKDIQQALIFYKKAA 336
+EKG +++DI A FY AA
Sbjct 674 HEKGLGIKQDIHLAKRFYDMAA 695
Score = 37.7 bits (86), Expect = 8e-06
Identities = 39/168 (23%), Positives = 72/168 (43%), Gaps = 17/168 (10%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
K +EG K Q L +Y +GL V + + AL +Y A + + LG Y G+G+
Sbjct 248 KLTEEGSPKGQTGLGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGV 307
Query 286 EKNYELGLTWIKKSVKQNYPDAYFTLAELYEK-------------GHIVQKDIQQALIFY 332
++ E LT + D T + ++ ++++D+ Q +Y
Sbjct 308 LQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQ---YY 364
Query 333 KKAANLRHATSAYRLGQI-FELGQGVTLDLKLAKRFYHQAASNFSSEA 379
+ A + LGQ+ G+GV + + A +++ AA+ +S A
Sbjct 365 QFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHA 412
>Q9UBV2 Protein sel-1 homolog 1 [Homo sapiens]
Length=794
Score = 79.3 bits (194), Expect = 5e-19
Identities = 44/131 (34%), Positives = 68/131 (52%), Gaps = 1/131 (1%)
Query 228 AQEGCIKAQNQLASMYLNGLDVT-QNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIE 286
A G A L MY G D+ Q+ AL +++K A +P G+ LG YL G G++
Sbjct 405 ANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQ 464
Query 287 KNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYR 346
NY+L L + +K+ +Q + D L +Y G V++D +QAL ++ A+ H + Y
Sbjct 465 VNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYN 524
Query 347 LGQIFELGQGV 357
L Q+ G GV
Sbjct 525 LAQMHASGTGV 535
Score = 65.9 bits (159), Expect = 1e-14
Identities = 45/156 (29%), Positives = 77/156 (49%), Gaps = 10/156 (6%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
K A G Q+ L YL G V N LAL +++K A Q +G+L LG +Y NG+G+
Sbjct 440 KAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGV 499
Query 286 EKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKK-------AANL 338
+++Y+ L + + + + A++ LA+++ G V + A+ +K + L
Sbjct 500 KRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERL 559
Query 339 RHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAASN 374
A ++Y+ G + V L LA++ Y A SN
Sbjct 560 MTAYNSYKDG---DYNAAVIQYLLLAEQGYEVAQSN 592
Score = 56.2 bits (134), Expect = 1e-11
Identities = 45/159 (28%), Positives = 76/159 (48%), Gaps = 4/159 (3%)
Query 216 EDIPNFKRTLKQAQEGCIKAQNQLASMYLNG-LDVTQNMSLALFWYEKTASQNDPEGELN 274
ED+ + + L A++G ++AQ L ++L+G V QN A ++ A+ +
Sbjct 358 EDLIQYYQFL--AEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAF 415
Query 275 LGKLYLNGLGI-EKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYK 333
LGK+Y G I ++ E L + KK+ P L Y G VQ + AL +++
Sbjct 416 LGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQ 475
Query 334 KAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAA 372
KAA +LG ++ G GV D K A ++++ A+
Sbjct 476 KAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLAS 514
Score = 48.9 bits (115), Expect = 3e-09
Identities = 29/91 (32%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query 283 LGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHAT 342
+G + Y L ++ Q Y A L + + G D + A I Y+ A+ +H+
Sbjct 605 VGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSA 664
Query 343 SA-YRLGQIFELGQGVTLDLKLAKRFYHQAA 372
A + LG + E G G+ D+ LAKRFY AA
Sbjct 665 QAMFNLGYMHEKGLGIKQDIHLAKRFYDMAA 695
Score = 45.1 bits (105), Expect = 4e-08
Identities = 36/146 (25%), Positives = 58/146 (40%), Gaps = 7/146 (5%)
Query 192 LQYHLGFDIIDSDYNTSQSLIINCEDIPNFKRTLKQAQEGCIKAQNQLASMYLNGLDVTQ 251
+ Y G I++ SQ ++ K A KA +++ L G + Q
Sbjct 185 MMYQTGMKILNGSNKKSQKR-------EAYRYLQKAASMNHTKALERVSYALLFGDYLPQ 237
Query 252 NMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTL 311
N+ A +EK + P+G+ LG LY +GLG+ + L + A+ L
Sbjct 238 NIQAAREMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVL 297
Query 312 AELYEKGHIVQKDIQQALIFYKKAAN 337
Y G V + + AL Y+ AN
Sbjct 298 GYRYWAGIGVLQSCESALTHYRLVAN 323
Score = 41.6 bits (96), Expect = 5e-07
Identities = 26/82 (32%), Positives = 40/82 (49%), Gaps = 1/82 (1%)
Query 256 ALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIK-KSVKQNYPDAYFTLAEL 314
AL + + ASQ + LG + G G + +YE + S +Q+ A F L +
Sbjct 614 ALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYM 673
Query 315 YEKGHIVQKDIQQALIFYKKAA 336
+EKG +++DI A FY AA
Sbjct 674 HEKGLGIKQDIHLAKRFYDMAA 695
Score = 32.7 bits (73), Expect = 3e-04
Identities = 40/199 (20%), Positives = 72/199 (36%), Gaps = 47/199 (24%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
K +EG K Q L +Y +GL V + + AL +Y A + + LG Y G+G+
Sbjct 248 KLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGV 307
Query 286 EKNYELGLTWIKKSVKQNYPDAYFT---------------------------LAELY--- 315
++ E LT + D T L + Y
Sbjct 308 LQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFL 367
Query 316 -EKGHI----------------VQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVT 358
EKG + V+++ Q+A ++ AAN ++ + LG+++ G +
Sbjct 368 AEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIV 427
Query 359 LDLKLAKRFYHQAASNFSS 377
Y + A++ +
Sbjct 428 PQSNETALHYFKKAADMGN 446
Score = 23.1 bits (48), Expect = 0.30
Identities = 33/166 (20%), Positives = 62/166 (37%), Gaps = 28/166 (17%)
Query 124 CEKSWLNFTIFYERESYTDGSYKIERYEIPDLNDESNPDIQYHKYYYIIEKSLSFY--HH 181
CE+ + + SY DG Y + L ++ Q + + + ++ S +
Sbjct 550 CERGRWSERLMTAYNSYKDGDYNAAVIQYLLLAEQGYEVAQSNAAFILDQREASIVGENE 609
Query 182 YLARALL--------------VEVLQYHLGFDIIDSDYNTSQSLIINCEDIPNFKRTLKQ 227
RALL +++ YH D DY T+ L
Sbjct 610 TYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETA-----------FIHYRLAS 658
Query 228 AQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGEL 273
Q+ +A L M+ GL + Q++ LA +Y+ A++ P+ ++
Sbjct 659 EQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYD-MAAEASPDAQV 703
>Q9LM25 ERAD-associated E3 ubiquitin-protein ligase component
HRD3A [Arabidopsis thaliana]
Length=678
Score = 78.2 bits (191), Expect = 1e-18
Identities = 45/160 (28%), Positives = 85/160 (53%), Gaps = 2/160 (1%)
Query 216 EDIPNFKRTLKQAQEGCIKAQNQLASMYLNGL-DVTQNMSLALFWYEKTASQNDPEGELN 274
E+ +F+ QAQ+G A ++ Y GL + ++ + AL W+ K + +P
Sbjct 225 EEDEDFQILEYQAQKGNANAMYKIGLFYYFGLRGLRRDHTKALHWFLKAVDKGEPRSMEL 284
Query 275 LGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGH-IVQKDIQQALIFYK 333
LG++Y G G+E+NY L W+ + K+ A+ + LY KG+ + +K+ +A +++
Sbjct 285 LGEIYARGAGVERNYTKALEWLTLAAKEGLYSAFNGIGYLYVKGYGVDKKNYTKAREYFE 344
Query 334 KAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAAS 373
KA + + Y LG ++ G GV D++ A +++ AA+
Sbjct 345 KAVDNEDPSGHYNLGVLYLKGIGVNRDVRQATKYFFVAAN 384
Score = 73.2 bits (178), Expect = 5e-17
Identities = 46/155 (30%), Positives = 77/155 (50%), Gaps = 11/155 (7%)
Query 228 AQEGCIKAQNQLASMYLNGLDVTQ-NMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIE 286
A+EG A N + +Y+ G V + N + A ++EK DP G NLG LYL G+G+
Sbjct 310 AKEGLYSAFNGIGYLYVKGYGVDKKNYTKAREYFEKAVDNEDPSGHYNLGVLYLKGIGVN 369
Query 287 KNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAAN-------LR 339
++ + + P A++ LA+++ G ++K+++ A FYK A R
Sbjct 370 RDVRQATKYFFVAANAGQPKAFYQLAKMFHTGVGLKKNLEMATSFYKLVAERGPWSSLSR 429
Query 340 HATSAYRLGQIFELGQGVTLDLKLAKRFYHQAASN 374
A AY G ++G+ + L ++A+ Y A SN
Sbjct 430 WALEAYLKG---DVGKALILYSRMAEMGYEVAQSN 461
Score = 46.2 bits (108), Expect = 2e-08
Identities = 51/203 (25%), Positives = 83/203 (41%), Gaps = 49/203 (24%)
Query 228 AQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKL--YLNG-LG 284
A G KA QLA M+ G+ + +N+ +A +Y K ++ P L+ L YL G +G
Sbjct 383 ANAGQPKAFYQLAKMFHTGVGLKKNLEMATSFY-KLVAERGPWSSLSRWALEAYLKGDVG 441
Query 285 ---------IEKNYELGLT---WIK------------------------------KSVKQ 302
E YE+ + WI ++ +Q
Sbjct 442 KALILYSRMAEMGYEVAQSNAAWILDKYGERSMCMGVSGFCTDKERHERAHSLWWRASEQ 501
Query 303 NYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLK 362
A + + Y G ++D +A Y A + +A + + LG + E GQG+ DL
Sbjct 502 GNEHAALLIGDAYYYGRGTERDFVRAAEAYMHAKSQSNAQAMFNLGYMHEHGQGLPFDLH 561
Query 363 LAKRFYHQAASNFSSEAKNRLDI 385
LAKR+Y + + S+A RL +
Sbjct 562 LAKRYYDE---SLQSDAAARLPV 581
Score = 23.9 bits (50), Expect = 0.17
Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 0/66 (0%)
Query 321 VQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAASNFSSEAK 380
+++D +AL ++ KA + S LG+I+ G GV + A + AA A
Sbjct 259 LRRDHTKALHWFLKAVDKGEPRSMELLGEIYARGAGVERNYTKALEWLTLAAKEGLYSAF 318
Query 381 NRLDIL 386
N + L
Sbjct 319 NGIGYL 324
Score = 20.8 bits (42), Expect = 1.5
Identities = 17/84 (20%), Positives = 30/84 (36%), Gaps = 20/84 (24%)
Query 261 EKTASQNDPEGELNLGKLYLNGLGIEKNYE--------------------LGLTWIKKSV 300
E +S DP + +G +Y G+ EK+ L T++++ +
Sbjct 116 EAASSAGDPHAQSIMGFVYGIGMMREKSKSKSFLHHNFAAAGGNMQSKMALAFTYLRQDM 175
Query 301 KQNYPDAYFTLAELYEKGHIVQKD 324
Y LAE ++ KD
Sbjct 176 HDKAVQLYAELAETAVNSFLISKD 199
>Q5UP92 Putative sel1-like repeat-containing protein L18 [Acanthamoeba
polyphaga mimivirus]
Length=584
Score = 77.4 bits (189), Expect = 2e-18
Identities = 61/238 (26%), Positives = 108/238 (45%), Gaps = 18/238 (8%)
Query 147 IERYEIPDLNDESNPDIQYHKYYYIIEKSLSF-YHHYLARALLVEVLQYHLGFDIIDSDY 205
+ RY D + S +I+ + IIE+++ Y Y + +YH+ FD++
Sbjct 60 VYRYLNQDAINLSQKNIKPINWENIIERAIDDQYFTYFLLFFAFDHDEYHVIFDVLFDVL 119
Query 206 NTSQSLIINCEDIPNFKRTLKQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTAS 265
F+ A+ G AQ L MY G+ +N+ A+ W K+A
Sbjct 120 ---------------FENVKLAAKTGDSMAQYNLGQMYYRGISTKKNIQKAIKWITKSAD 164
Query 266 QNDPEGELNLGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDI 325
QN+ G +NL + Y G G+ + + ++++ QN+ A F L +Y + D
Sbjct 165 QNNKYGLINLARFYEYGDGVLLDIDKATQLLEQASCQNFSKAQFYLGRIYM--YKDPPDY 222
Query 326 QQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAASNFSSEAKNRL 383
+ A +Y++AAN H+++ Y + ++ G+ V D K A + AAS + AK +L
Sbjct 223 KLAFKYYQQAANQNHSSAQYFIAVFYKTGKCVAQDYKKAVHWLTLAASQGLNSAKIKL 280
Score = 58.5 bits (140), Expect = 2e-12
Identities = 38/145 (26%), Positives = 70/145 (48%), Gaps = 10/145 (7%)
Query 216 EDIPNFKRTLKQAQEGCIK----AQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEG 271
+D P++K K Q+ + AQ +A Y G V Q+ A+ W ASQ
Sbjct 217 KDPPDYKLAFKYYQQAANQNHSSAQYFIAVFYKTGKCVAQDYKKAVHWLTLAASQGLNSA 276
Query 272 ELNLGKLYLNGLGIEKNYELGLTWIKKSV----KQNYPD--AYFTLAELYEKGHIVQKDI 325
++ L ++Y+ G+ +E+NY + S+ NY D A LA +Y++G ++K+I
Sbjct 277 KIKLAEMYMKGIDVEQNYHKAFELLNSSIYDDGTNNYYDEVAMTELACMYKRGLGIEKNI 336
Query 326 QQALIFYKKAANLRHATSAYRLGQI 350
+A+ + K+ N ++ + + I
Sbjct 337 SKAIYLHIKSRNTKNIFKIFEINTI 361
Score = 34.3 bits (77), Expect = 9e-05
Identities = 33/157 (21%), Positives = 59/157 (38%), Gaps = 44/157 (28%)
Query 264 ASQNDPEGELNLGKLYLN--GLGIEKNYELGLTW-------------------------- 295
A +ND E + + YLN + + + + W
Sbjct 48 AGKNDREAQDEIVYRYLNQDAINLSQKNIKPINWENIIERAIDDQYFTYFLLFFAFDHDE 107
Query 296 ---------------IKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRH 340
+K + K A + L ++Y +G +K+IQ+A+ + K+A+ +
Sbjct 108 YHVIFDVLFDVLFENVKLAAKTGDSMAQYNLGQMYYRGISTKKNIQKAIKWITKSADQNN 167
Query 341 ATSAYRLGQIFELGQGVTLDLKLAKRFYHQAA-SNFS 376
L + +E G GV LD+ A + QA+ NFS
Sbjct 168 KYGLINLARFYEYGDGVLLDIDKATQLLEQASCQNFS 204
>Q9ZKB5 Putative beta-lactamase HcpC [Helicobacter pylori (strain
J99 / ATCC 700824)]
Length=290
Score = 73.9 bits (180), Expect = 7e-18
Identities = 43/156 (28%), Positives = 73/156 (47%), Gaps = 4/156 (3%)
Query 220 NFKRTLKQAQEGCIKAQNQ----LASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNL 275
+F + K ++ C +N L +Y G V +N+ A +Y K N G L
Sbjct 44 DFTQAKKYFEKACDLKENSGCFNLGVLYYQGHGVEKNLKKAASFYSKACDLNYSNGCHLL 103
Query 276 GKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKA 335
G LY +G G+ +N L + K+ Y + +L +Y G +V +D ++A+ ++ KA
Sbjct 104 GNLYYSGQGVSQNTNKALQYYSKACDLKYAEGCASLGGIYHDGKVVTRDFKKAVEYFTKA 163
Query 336 ANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQA 371
+L LG +++ G+G DLK A Y +A
Sbjct 164 CDLNDGDGCTILGSLYDAGRGTPKDLKKALASYDKA 199
Score = 72.4 bits (176), Expect = 2e-17
Identities = 40/121 (33%), Positives = 63/121 (52%), Gaps = 0/121 (0%)
Query 251 QNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFT 310
Q+ + A ++EK + G NLG LY G G+EKN + ++ K+ NY +
Sbjct 43 QDFTQAKKYFEKACDLKENSGCFNLGVLYYQGHGVEKNLKKAASFYSKACDLNYSNGCHL 102
Query 311 LAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQ 370
L LY G V ++ +AL +Y KA +L++A LG I+ G+ VT D K A ++ +
Sbjct 103 LGNLYYSGQGVSQNTNKALQYYSKACDLKYAEGCASLGGIYHDGKVVTRDFKKAVEYFTK 162
Query 371 A 371
A
Sbjct 163 A 163
Score = 70.1 bits (170), Expect = 1e-16
Identities = 38/133 (29%), Positives = 68/133 (51%), Gaps = 0/133 (0%)
Query 239 LASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKK 298
L ++Y +G V+QN + AL +Y K EG +LG +Y +G + ++++ + + K
Sbjct 103 LGNLYYSGQGVSQNTNKALQYYSKACDLKYAEGCASLGGIYHDGKVVTRDFKKAVEYFTK 162
Query 299 SVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVT 358
+ N D L LY+ G KD+++AL Y KA +L+ + + G ++ G+G
Sbjct 163 ACDLNDGDGCTILGSLYDAGRGTPKDLKKALASYDKACDLKDSPGCFNAGNMYHHGEGAA 222
Query 359 LDLKLAKRFYHQA 371
+ K A Y +A
Sbjct 223 KNFKEALARYSKA 235
Score = 64.3 bits (155), Expect = 1e-14
Identities = 70/265 (26%), Positives = 110/265 (42%), Gaps = 28/265 (11%)
Query 135 YERESYTDGSYKIERYEIPDLNDES---NPDIQYHKYYYIIEKSLSFYHHYLARALLVEV 191
Y+ + +T E+ DL + S N + Y++ + + EK+L + ++A
Sbjct 40 YKEQDFTQAKKYFEK--ACDLKENSGCFNLGVLYYQGHGV-EKNLKKAASFYSKAC---D 93
Query 192 LQYHLGFDIIDSDYNTSQSLIINCEDIPNFKRT---LKQAQEGCIKAQNQLASMYLNGLD 248
L Y G ++ + Y + Q + N + LK A EGC L +Y +G
Sbjct 94 LNYSNGCHLLGNLYYSGQGVSQNTNKALQYYSKACDLKYA-EGCAS----LGGIYHDGKV 148
Query 249 VTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAY 308
VT++ A+ ++ K ND +G LG LY G G K+ + L K+
Sbjct 149 VTRDFKKAVEYFTKACDLNDGDGCTILGSLYDAGRGTPKDLKKALASYDKACDLKDSPGC 208
Query 309 FTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFY 368
F +Y G K+ ++AL Y KA L + + LG + G+G T + K
Sbjct 209 FNAGNMYHHGEGAAKNFKEALARYSKACELENGGGCFNLGAMQYNGEGATRNEK------ 262
Query 369 HQAASNFSS----EAKNRLDILDQL 389
QA NF AK DIL QL
Sbjct 263 -QAIENFKKGCKLGAKGACDILKQL 286
>O25728 Putative beta-lactamase HcpC [Helicobacter pylori (strain
ATCC 700392 / 26695)]
Length=290
Score = 73.9 bits (180), Expect = 7e-18
Identities = 43/156 (28%), Positives = 73/156 (47%), Gaps = 4/156 (3%)
Query 220 NFKRTLKQAQEGCIKAQNQ----LASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNL 275
+F + K ++ C +N L +Y G V +N+ A +Y K N G L
Sbjct 44 DFTQAKKYFEKACDLKENSGCFNLGVLYYQGQGVEKNLKKAASFYAKACDLNYSNGCHLL 103
Query 276 GKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKA 335
G LY +G G+ +N L + K+ Y + +L +Y G +V +D ++A+ ++ KA
Sbjct 104 GNLYYSGQGVSQNTNKALQYYSKACDLKYAEGCASLGGIYHDGKVVTRDFKKAVEYFTKA 163
Query 336 ANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQA 371
+L LG +++ G+G DLK A Y +A
Sbjct 164 CDLNDGDGCTILGSLYDAGRGTPKDLKKALASYDKA 199
Score = 72.0 bits (175), Expect = 3e-17
Identities = 39/133 (29%), Positives = 69/133 (52%), Gaps = 0/133 (0%)
Query 239 LASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKK 298
L ++Y +G V+QN + AL +Y K EG +LG +Y +G + ++++ + + K
Sbjct 103 LGNLYYSGQGVSQNTNKALQYYSKACDLKYAEGCASLGGIYHDGKVVTRDFKKAVEYFTK 162
Query 299 SVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVT 358
+ N D L LY+ G KD+++AL Y KA +L+ + + G ++ G+G T
Sbjct 163 ACDLNDGDGCTILGSLYDAGRGTPKDLKKALASYDKACDLKDSPGCFNAGNMYHHGEGAT 222
Query 359 LDLKLAKRFYHQA 371
+ K A Y +A
Sbjct 223 KNFKEALARYSKA 235
Score = 65.9 bits (159), Expect = 4e-15
Identities = 64/225 (28%), Positives = 94/225 (42%), Gaps = 22/225 (10%)
Query 172 IEKSLSFYHHYLARALLVEVLQYHLGFDIIDSDYNTSQSLIINCEDIPNFKRT---LKQA 228
+EK+L + A+A L Y G ++ + Y + Q + N + LK A
Sbjct 77 VEKNLKKAASFYAKAC---DLNYSNGCHLLGNLYYSGQGVSQNTNKALQYYSKACDLKYA 133
Query 229 QEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKN 288
EGC L +Y +G VT++ A+ ++ K ND +G LG LY G G K+
Sbjct 134 -EGCAS----LGGIYHDGKVVTRDFKKAVEYFTKACDLNDGDGCTILGSLYDAGRGTPKD 188
Query 289 YELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLG 348
+ L K+ F +Y G K+ ++AL Y KA L + + LG
Sbjct 189 LKKALASYDKACDLKDSPGCFNAGNMYHHGEGATKNFKEALARYSKACELENGGGCFNLG 248
Query 349 QIFELGQGVTLDLKLAKRFYHQAASNFSS----EAKNRLDILDQL 389
+ G+GVT + K QA NF AK DIL QL
Sbjct 249 AMQYNGEGVTRNEK-------QAIENFKKGCKLGAKGACDILKQL 286
Score = 51.6 bits (122), Expect = 2e-10
Identities = 31/108 (29%), Positives = 57/108 (53%), Gaps = 6/108 (6%)
Query 265 SQNDPEGELNLG-KLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQK 323
++ DP+ + LG K Y EK++ + +K+ F L LY +G V+K
Sbjct 25 AEQDPKELVGLGAKSYK-----EKDFTQAKKYFEKACDLKENSGCFNLGVLYYQGQGVEK 79
Query 324 DIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQA 371
++++A FY KA +L ++ + LG ++ GQGV+ + A ++Y +A
Sbjct 80 NLKKAASFYAKACDLNYSNGCHLLGNLYYSGQGVSQNTNKALQYYSKA 127
>Q5TEA6 Protein sel-1 homolog 2 [Homo sapiens]
Length=688
Score = 73.2 bits (178), Expect = 5e-17
Identities = 44/145 (30%), Positives = 70/145 (48%), Gaps = 1/145 (1%)
Query 225 LKQAQEGCIKAQNQLASMYLNG-LDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGL 283
LK A+ G A + MYL G V QN + A ++ AS+ + G LG LY +G
Sbjct 326 LKAAKAGSANAMAFIGKMYLEGNAAVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGK 385
Query 284 GIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATS 343
G+ NY L + +K+ ++ +PDA F L +Y G + KD + A ++ A+ +
Sbjct 386 GVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLA 445
Query 344 AYRLGQIFELGQGVTLDLKLAKRFY 368
Y L +++ G GV + A Y
Sbjct 446 IYYLAKMYATGTGVVRSCRTAVELY 470
Score = 51.2 bits (121), Expect = 5e-10
Identities = 38/151 (25%), Positives = 70/151 (46%), Gaps = 6/151 (4%)
Query 228 AQEGCIKAQNQLASMYL---NGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNG-L 283
A+ G ++ Q L ++L GLD Q+ AL ++ K A +GK+YL G
Sbjct 292 AERGDVQIQVSLGQLHLIGRKGLD--QDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNA 349
Query 284 GIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATS 343
+ +N + + + L LY G V + +AL +++KAA +
Sbjct 350 AVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDA 409
Query 344 AYRLGQIFELGQGVTLDLKLAKRFYHQAASN 374
++LG ++ G G+ D KLA ++++ A+ +
Sbjct 410 QFQLGFMYYSGSGIWKDYKLAFKYFYLASQS 440
Score = 47.8 bits (112), Expect = 6e-09
Identities = 44/166 (27%), Positives = 74/166 (45%), Gaps = 17/166 (10%)
Query 228 AQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEK 287
A+EG KAQN L + G+ + + + AL +Y ++ + ++ LG YL+G+ + +
Sbjct 174 AKEGSCKAQNALGFLSSYGIGMEYDQAKALIYYTFGSAGGNMMSQMILGYRYLSGINVLQ 233
Query 288 NYELGLTWIKK---------SVKQNYPDAYFTLAE----LYEKGHIVQKDIQQALIFYKK 334
N E+ L++ KK + P L E L I+ DI Q +YK
Sbjct 234 NCEVALSYYKKVADYIADTFEKSEGVPVEKVRLTERPENLSSNSEILDWDIYQ---YYKF 290
Query 335 AANLRHATSAYRLGQIFELG-QGVTLDLKLAKRFYHQAASNFSSEA 379
A LGQ+ +G +G+ D A ++ +AA S+ A
Sbjct 291 LAERGDVQIQVSLGQLHLIGRKGLDQDYYKALHYFLKAAKAGSANA 336
Score = 47.8 bits (112), Expect = 6e-09
Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query 281 NGLGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRH 340
N L EK Y + L ++ Q A + + + G+ +KD Q A Y AAN H
Sbjct 527 NILEKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATHYSIAANKYH 586
Query 341 -ATSAYRLGQIFELGQGVTLDLKLAKRFYHQAA 372
A + + L ++E G G+T D+ LA+R Y AA
Sbjct 587 NAQAMFNLAYMYEHGLGITKDIHLARRLYDMAA 619
Score = 42.4 bits (98), Expect = 3e-07
Identities = 37/142 (26%), Positives = 63/142 (44%), Gaps = 9/142 (6%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
K A G +KA ++A L G QN++ A+ YE A + + + LG L G+G+
Sbjct 136 KAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGM 195
Query 286 EKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAY 345
E + L + + L Y G V ++ + AL +YKK A+
Sbjct 196 EYDQAKALIYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVADY------- 248
Query 346 RLGQIFELGQGVTLD-LKLAKR 366
+ FE +GV ++ ++L +R
Sbjct 249 -IADTFEKSEGVPVEKVRLTER 269
Score = 42.0 bits (97), Expect = 4e-07
Identities = 47/187 (25%), Positives = 77/187 (41%), Gaps = 38/187 (20%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
K A++G AQ QL MY +G + ++ LA ++ + P L K+Y G G+
Sbjct 400 KAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGV 459
Query 286 EKN-----------YELGLTWIKKSVKQ--NYPDA--------YFTLAEL-YE------- 316
++ ELG W +K + Y D Y LAE+ YE
Sbjct 460 VRSCRTAVELYKGVCELG-HWAEKFLTAYFAYKDGDIDSSLVQYALLAEMGYEVAQSNSA 518
Query 317 ------KGHIVQKD--IQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFY 368
K +I++K+ AL+ + +AA +A + ++G G G D + A Y
Sbjct 519 FILESKKANILEKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTAATHY 578
Query 369 HQAASNF 375
AA+ +
Sbjct 579 SIAANKY 585
Score = 35.4 bits (80), Expect = 4e-05
Identities = 50/225 (22%), Positives = 83/225 (37%), Gaps = 49/225 (22%)
Query 117 QTGQPLNCEKSWLNFTIFYERESYTDGSYKIERYEIPDLNDESNPDIQYHK----YYYII 172
Q+GQPL I+Y + Y G+ + ++ +K +
Sbjct 439 QSGQPL---------AIYYLAKMYATGTGVVR---------SCRTAVELYKGVCELGHWA 480
Query 173 EKSLSFYHHYLARALLVEVLQYHLGFDIIDSDYNTSQSLIINCEDIPNFKRTLKQAQEGC 232
EK L+ Y Y + ++QY L + + Y +QS
Sbjct 481 EKFLTAYFAYKDGDIDSSLVQYAL---LAEMGYEVAQS---------------------- 515
Query 233 IKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELG 292
+ L S N L+ + +AL + + A Q + + +G + G G +K+Y+
Sbjct 516 -NSAFILESKKANILEKEKMYPMALLLWNRAAIQGNAFARVKIGDYHYYGYGTKKDYQTA 574
Query 293 LTWIKKSV-KQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAA 336
T + K + A F LA +YE G + KDI A Y AA
Sbjct 575 ATHYSIAANKYHNAQAMFNLAYMYEHGLGITKDIHLARRLYDMAA 619
>P77296 Sel1-repeat-containing protein YbeT [Escherichia coli
(strain K12)]
Length=184
Score = 65.9 bits (159), Expect = 8e-16
Identities = 40/125 (32%), Positives = 65/125 (52%), Gaps = 10/125 (8%)
Query 228 AQEGCIKAQNQLASMYLNG-----LDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNG 282
A G +Q +L YL+G LD TQ A +WYE++A Q +P + LG +YL G
Sbjct 58 AIHGHSTSQYRLGEFYLHGSDGKPLDYTQ----ARYWYEQSAEQENPRAQSKLGWIYLKG 113
Query 283 LGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHAT 342
LG++ + + W K++ +Q Y A +TL +Y G + + ++ + K A +H
Sbjct 114 LGVKPDTRKAILWYKEAAEQGYAHAQYTLGLIYRNGSGINVNHYESQKWLKLTAK-QHYK 172
Query 343 SAYRL 347
+A RL
Sbjct 173 NAERL 177
Score = 59.7 bits (143), Expect = 1e-13
Identities = 31/89 (35%), Positives = 49/89 (55%), Gaps = 0/89 (0%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
+ A++ +AQ++L +YL GL V + A+ WY++ A Q + LG +Y NG GI
Sbjct 93 QSAEQENPRAQSKLGWIYLKGLGVKPDTRKAILWYKEAAEQGYAHAQYTLGLIYRNGSGI 152
Query 286 EKNYELGLTWIKKSVKQNYPDAYFTLAEL 314
N+ W+K + KQ+Y +A LA L
Sbjct 153 NVNHYESQKWLKLTAKQHYKNAERLLAGL 181
Score = 56.2 bits (134), Expect = 2e-12
Identities = 39/120 (33%), Positives = 62/120 (52%), Gaps = 9/120 (8%)
Query 261 EKTASQNDPEGELNLGKLYLNGL-GIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGH 319
E +A + LG+ YL+G G +Y W ++S +Q P A L +Y KG
Sbjct 55 ELSAIHGHSTSQYRLGEFYLHGSDGKPLDYTQARYWYEQSAEQENPRAQSKLGWIYLKGL 114
Query 320 IVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLD-------LKL-AKRFYHQA 371
V+ D ++A+++YK+AA +A + Y LG I+ G G+ ++ LKL AK+ Y A
Sbjct 115 GVKPDTRKAILWYKEAAEQGYAHAQYTLGLIYRNGSGINVNHYESQKWLKLTAKQHYKNA 174
>O24968 Putative beta-lactamase HcpD [Helicobacter pylori (strain
ATCC 700392 / 26695)]
Length=306
Score = 65.9 bits (159), Expect = 4e-15
Identities = 38/130 (29%), Positives = 66/130 (51%), Gaps = 0/130 (0%)
Query 239 LASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKK 298
L SMY +G V +N+ A+++Y + +LG +Y NG G+++NY L K
Sbjct 102 LGSMYEDGDGVQKNLPKAIYYYRRGCHLKGGVSCGSLGFMYFNGTGVKQNYAKALFLSKY 161
Query 299 SVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVT 358
+ NY + + +Y VQKD+++AL +K+ +L+ S LG ++E+G V
Sbjct 162 ACSLNYGISCNFVGYMYRNAKGVQKDLKKALANFKRGCHLKDGASCVSLGYMYEVGMDVK 221
Query 359 LDLKLAKRFY 368
+ + A Y
Sbjct 222 QNGEQALNLY 231
Score = 64.7 bits (156), Expect = 1e-14
Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 5/155 (3%)
Query 239 LASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKK 298
L MY NG V QN + ALF + S N +G +Y N G++K+ + L K+
Sbjct 138 LGFMYFNGTGVKQNYAKALFLSKYACSLNYGISCNFVGYMYRNAKGVQKDLKKALANFKR 197
Query 299 SVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVT 358
+ +L +YE G V+++ +QAL YKK L+ + + + ++ G+GV
Sbjct 198 GCHLKDGASCVSLGYMYEVGMDVKQNGEQALNLYKKGCYLKRGSGCHNVAVMYYTGKGVP 257
Query 359 LDLKLAKRFYHQAAS-NFSSEAKNRLDILDQLINK 392
DL A +Y + + FS K +L+++I K
Sbjct 258 KDLDKAISYYKKGCTLGFSGSCK----VLEEVIGK 288
Score = 48.9 bits (115), Expect = 1e-09
Identities = 26/102 (25%), Positives = 55/102 (54%), Gaps = 0/102 (0%)
Query 256 ALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTLAELY 315
A+ +Y+++ + G +LG +Y +G G+++N + + ++ A +L +Y
Sbjct 47 AVAFYKRSCNLRVGVGCTSLGSMYEDGDGVDQNITKAVFYYRRGCNLRNHLACASLGSMY 106
Query 316 EKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGV 357
E G VQK++ +A+ +Y++ +L+ S LG ++ G GV
Sbjct 107 EDGDGVQKNLPKAIYYYRRGCHLKGGVSCGSLGFMYFNGTGV 148
Score = 46.6 bits (109), Expect = 8e-09
Identities = 30/114 (26%), Positives = 53/114 (46%), Gaps = 0/114 (0%)
Query 237 NQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWI 296
N + MY N V +++ AL +++ D ++LG +Y G+ +++N E L
Sbjct 172 NFVGYMYRNAKGVQKDLKKALANFKRGCHLKDGASCVSLGYMYEVGMDVKQNGEQALNLY 231
Query 297 KKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQI 350
KK +A +Y G V KD+ +A+ +YKK L + S L ++
Sbjct 232 KKGCYLKRGSGCHNVAVMYYTGKGVPKDLDKAISYYKKGCTLGFSGSCKVLEEV 285
Score = 44.7 bits (104), Expect = 3e-08
Identities = 23/83 (28%), Positives = 43/83 (52%), Gaps = 0/83 (0%)
Query 288 NYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRL 347
+Y + + K+S +L +YE G V ++I +A+ +Y++ NLR+ + L
Sbjct 43 DYHKAVAFYKRSCNLRVGVGCTSLGSMYEDGDGVDQNITKAVFYYRRGCNLRNHLACASL 102
Query 348 GQIFELGQGVTLDLKLAKRFYHQ 370
G ++E G GV +L A +Y +
Sbjct 103 GSMYEDGDGVQKNLPKAIYYYRR 125
Score = 36.6 bits (83), Expect = 1e-05
Identities = 20/69 (29%), Positives = 37/69 (54%), Gaps = 6/69 (9%)
Query 306 DAYFTLA-ELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLA 364
+ YF +A + +++G D +A+ FYK++ NLR LG ++E G GV ++ A
Sbjct 29 EKYFKMATQAFKRG-----DYHKAVAFYKRSCNLRVGVGCTSLGSMYEDGDGVDQNITKA 83
Query 365 KRFYHQAAS 373
+Y + +
Sbjct 84 VFYYRRGCN 92
>O25021 Putative beta-lactamase HcpE [Helicobacter pylori (strain
ATCC 700392 / 26695)]
Length=355
Score = 63.9 bits (154), Expect = 2e-14
Identities = 37/129 (29%), Positives = 63/129 (49%), Gaps = 2/129 (2%)
Query 226 KQAQEGCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGI 285
K +G + QL +Y NG + AL +Y+ +D EG LG LY GLG
Sbjct 52 KACNDGVSEGCTQLGIIYENGQGTRIDYKKALEYYKTACQADDREGCFGLGGLYDEGLGT 111
Query 286 EKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAY 345
+NY+ + K+ +P++ + L +Y++ ++ + QA+ +Y+K+ N A Y
Sbjct 112 TQNYQEAIDAYAKACVLKHPESCYNLGIIYDRK--IKGNADQAVTYYQKSCNFDMAKGCY 169
Query 346 RLGQIFELG 354
LG +E G
Sbjct 170 VLGVAYEKG 178
Score = 63.5 bits (153), Expect = 3e-14
Identities = 37/125 (30%), Positives = 67/125 (54%), Gaps = 1/125 (1%)
Query 247 LDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNG-LGIEKNYELGLTWIKKSVKQNYP 305
L+V Q+ A+ +Y K +D + LG L+ NG G+++++E+ +++K+ N
Sbjct 180 LEVKQSNHKAVIYYLKACRLDDGQACRALGSLFENGDAGLDEDFEVAFDYLQKACGLNNS 239
Query 306 DAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAK 365
+L +Y G V+KD Q+A F+K+A ++ A S R+G ++ G V DL+ A
Sbjct 240 GGCASLGSMYMLGRYVKKDPQKAFNFFKQACDMGSAVSCSRMGFMYSQGDAVPKDLRKAL 299
Query 366 RFYHQ 370
Y +
Sbjct 300 DNYER 304
Score = 57.8 bits (138), Expect = 2e-12
Identities = 37/124 (30%), Positives = 61/124 (49%), Gaps = 3/124 (2%)
Query 252 NMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFTL 311
N S A +++K + EG LG +Y NG G +Y+ L + K + + + + F L
Sbjct 42 NYSKATSYFKKACNDGVSEGCTQLGIIYENGQGTRIDYKKALEYYKTACQADDREGCFGL 101
Query 312 AELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQA 371
LY++G ++ Q+A+ Y KA L+H S Y LG I++ D + Y+Q
Sbjct 102 GGLYDEGLGTTQNYQEAIDAYAKACVLKHPESCYNLGIIYDRKIKGNADQAVT---YYQK 158
Query 372 ASNF 375
+ NF
Sbjct 159 SCNF 162
Score = 42.4 bits (98), Expect = 2e-07
Identities = 24/119 (20%), Positives = 58/119 (49%), Gaps = 1/119 (1%)
Query 234 KAQNQLASMYLNG-LDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELG 292
+A L S++ NG + ++ +A + +K N+ G +LG +Y+ G ++K+ +
Sbjct 203 QACRALGSLFENGDAGLDEDFEVAFDYLQKACGLNNSGGCASLGSMYMLGRYVKKDPQKA 262
Query 293 LTWIKKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIF 351
+ K++ + + +Y +G V KD+++AL Y++ ++ + L ++
Sbjct 263 FNFFKQACDMGSAVSCSRMGFMYSQGDAVPKDLRKALDNYERGCDMGDEVGCFALAGMY 321
Score = 29.3 bits (64), Expect = 0.003
Identities = 22/100 (22%), Positives = 39/100 (39%), Gaps = 4/100 (4%)
Query 239 LASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKK 298
L SMY+ G V ++ A ++++ +G +Y G + K+ L ++
Sbjct 245 LGSMYMLGRYVKKDPQKAFNFFKQACDMGSAVSCSRMGFMYSQGDAVPKDLRKALDNYER 304
Query 299 SVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANL 338
F LA +Y KD + A++ Y K L
Sbjct 305 GCDMGDEVGCFALAGMYYN----MKDKENAIMIYDKGCKL 340
Score = 23.5 bits (49), Expect = 0.20
Identities = 17/57 (30%), Positives = 27/57 (47%), Gaps = 1/57 (2%)
Query 226 KQAQE-GCIKAQNQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLN 281
KQA + G + +++ MY G V +++ AL YE+ D G L +Y N
Sbjct 267 KQACDMGSAVSCSRMGFMYSQGDAVPKDLRKALDNYERGCDMGDEVGCFALAGMYYN 323
>O25001 Beta-lactamase HcpA [Helicobacter pylori (strain ATCC
700392 / 26695)]
Length=250
Score = 58.5 bits (140), Expect = 7e-13
Identities = 33/115 (29%), Positives = 56/115 (49%), Gaps = 0/115 (0%)
Query 239 LASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKK 298
L + Y G V +++ A+ +Y K ND G LG LY NG G+ K+ + + K
Sbjct 67 LGAFYEEGKGVGKDLKKAIQFYTKGCELNDGYGCNLLGNLYYNGQGVSKDAKKASQYYSK 126
Query 299 SVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFEL 353
+ N+ + L L+ G KD+++AL Y+KA +L+ + G I+ +
Sbjct 127 ACDLNHAEGCMVLGSLHHYGVGTPKDLRKALDLYEKACDLKDSPGCINAGYIYSV 181
Score = 56.6 bits (135), Expect = 3e-12
Identities = 44/157 (28%), Positives = 65/157 (41%), Gaps = 15/157 (10%)
Query 237 NQLASMYLNGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWI 296
N L ++Y NG V+++ A +Y K N EG + LG L+ G+G K+ L
Sbjct 101 NLLGNLYYNGQGVSKDAKKASQYYSKACDLNHAEGCMVLGSLHHYGVGTPKDLRKALDLY 160
Query 297 KKSVKQNYPDAYFTLAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQG 356
+K+ +Y V K+ ++A++ Y KA L+ Y LG + QG
Sbjct 161 EKACDLKDSPGCINAGYIYS----VTKNFKEAIVRYSKACELKDGRGCYNLGVMQYNAQG 216
Query 357 VTLDLKLAKRFYHQAASNF----SSEAKNRLDILDQL 389
D K QA NF S K D L +L
Sbjct 217 TAKDEK-------QAVENFKKGCKSSVKEACDALKEL 246
Score = 55.8 bits (133), Expect = 5e-12
Identities = 36/121 (30%), Positives = 54/121 (45%), Gaps = 0/121 (0%)
Query 251 QNMSLALFWYEKTASQNDPEGELNLGKLYLNGLGIEKNYELGLTWIKKSVKQNYPDAYFT 310
Q+ + A +EK + G + LG Y G G+ K+ + + + K + N
Sbjct 43 QDFAQAKTHFEKACELKNGFGCVFLGAFYEEGKGVGKDLKKAIQFYTKGCELNDGYGCNL 102
Query 311 LAELYEKGHIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQ 370
L LY G V KD ++A +Y KA +L HA LG + G G DL+ A Y +
Sbjct 103 LGNLYYNGQGVSKDAKKASQYYSKACDLNHAEGCMVLGSLHHYGVGTPKDLRKALDLYEK 162
Query 371 A 371
A
Sbjct 163 A 163
Score = 35.8 bits (81), Expect = 2e-05
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 0/47 (0%)
Query 322 QKDIQQALIFYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFY 368
++D QA ++KA L++ LG +E G+GV DLK A +FY
Sbjct 42 KQDFAQAKTHFEKACELKNGFGCVFLGAFYEEGKGVGKDLKKAIQFY 88
>J9VSG5 Chitin synthase regulator 2 [Cryptococcus neoformans var.
grubii serotype A (strain H99 / ATCC 208821 / CBS 10515
/ FGSC 9487)]
Length=485
Score = 58.2 bits (139), Expect = 2e-12
Identities = 42/142 (30%), Positives = 75/142 (53%), Gaps = 7/142 (5%)
Query 245 NGLDVTQNMSLALFWYEKTASQNDPEGELNLGKLYLNG-LGIEKNYELGLTWIKKSVK-- 301
+G ++ + A+ +Y+K A P LG LNG LG + + G+ W+K+S +
Sbjct 215 HGWGCRRDSAKAVSFYKKAAVGLHPGAMYRLGTAELNGALGFPRRPKEGVKWLKRSAEHA 274
Query 302 -QNYPDAYFTLAELYEKG--HIVQKDIQQALIFYKKAANLRHATSAYRLGQIFELGQ-GV 357
+ +P A LA L+E+G ++V D A ++A L +A SA++LG+ +E G+ G
Sbjct 275 TEEFPHALHELALLHERGIENVVFVDNDYAAELLAQSAELGYAPSAFKLGECYEYGKMGC 334
Query 358 TLDLKLAKRFYHQAASNFSSEA 379
+D L+ +Y+ +A +A
Sbjct 335 PVDPALSIHYYNISAQQDHKDA 356
Score = 51.6 bits (122), Expect = 3e-10
Identities = 46/173 (27%), Positives = 78/173 (45%), Gaps = 5/173 (3%)
Query 216 EDIPNFKRTLKQAQEGCIKAQNQLASMYLNGLD--VTQNMSLALFWYEKTASQNDPEGEL 273
E + KR+ + A E A ++LA ++ G++ V + A ++A
Sbjct 262 EGVKWLKRSAEHATEEFPHALHELALLHERGIENVVFVDNDYAAELLAQSAELGYAPSAF 321
Query 274 NLGKLYLNG-LGIEKNYELGLTWIKKSVKQNYPDAYFTLAELYEKGH--IVQKDIQQALI 330
LG+ Y G +G + L + + S +Q++ DA F L Y G ++ + +A +
Sbjct 322 KLGECYEYGKMGCPVDPALSIHYYNISAQQDHKDACFALTAWYLVGSPGVLPQSDTEAYL 381
Query 331 FYKKAANLRHATSAYRLGQIFELGQGVTLDLKLAKRFYHQAASNFSSEAKNRL 383
+ KKAA L A + Y +G E G G+ + + A +Y QAA A RL
Sbjct 382 WAKKAAELGLAKAQYAVGYFTETGIGIEANPQAALTWYKQAAEGGDKRAAKRL 434
Score = 44.7 bits (104), Expect = 5e-08
Identities = 26/91 (29%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
Query 261 EKTASQNDPEGELNLGKLYLNGLGI---EKNYELGLTWIKKSVKQNYPDAYFTLAELYEK 317
++ A + P+ + L Y NG+G +++++ + K +PDA + E
Sbjct 156 KRLADRGFPDAQYFLADCYANGIGTARGKQDFDRAFPLFILAAKHGHPDACYRAGTCCEH 215
Query 318 GHIVQKDIQQALIFYKKAANLRHATSAYRLG 348
G ++D +A+ FYKKAA H + YRLG
Sbjct 216 GWGCRRDSAKAVSFYKKAAVGLHPGAMYRLG 246
Score = 40.4 bits (93), Expect = 1e-06
Identities = 28/91 (31%), Positives = 40/91 (44%), Gaps = 3/91 (3%)
Query 296 IKKSVKQNYPDAYFTLAELYEKGHIV---QKDIQQALIFYKKAANLRHATSAYRLGQIFE 352
+K+ + +PDA + LA+ Y G ++D +A + AA H + YR G E
Sbjct 155 LKRLADRGFPDAQYFLADCYANGIGTARGKQDFDRAFPLFILAAKHGHPDACYRAGTCCE 214
Query 353 LGQGVTLDLKLAKRFYHQAASNFSSEAKNRL 383
G G D A FY +AA A RL
Sbjct 215 HGWGCRRDSAKAVSFYKKAAVGLHPGAMYRL 245
Lambda K H a alpha
0.320 0.137 0.406 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 2696287
Database: 4e2ee410b49d944265c4e1b512211c09.SwissProt.fasta
Posted date: May 20, 2024 7:26 PM
Number of letters in database: 8,791
Number of sequences in database: 17
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
