BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 22caf3ea454ab4f03243fc67387dccbe.SwissProt.fasta
21 sequences; 6,766 total letters
Query= ACIAD1883
Length=250
Score E
Sequences producing significant alignments: (Bits) Value
P9WGR7 Uncharacterized oxidoreductase Rv0945 [Mycobacterium tuber... 232 5e-80
P9WGR6 Uncharacterized oxidoreductase MT0971 [Mycobacterium tuber... 232 5e-80
P25970 Uncharacterized oxidoreductase MXAN_5909 [Myxococcus xanth... 122 6e-37
Q05016 NADP-dependent 3-hydroxy acid dehydrogenase [Saccharomyces... 102 2e-29
Q9P7B4 NADP-dependent 3-hydroxy acid dehydrogenase [Schizosacchar... 101 5e-29
Q9Y140 Dehydrogenase/reductase SDR family protein 7-like [Drosoph... 101 1e-28
Q4A054 Uncharacterized oxidoreductase SSP0419 [Staphylococcus sap... 97.8 7e-28
Q6IAN0 Dehydrogenase/reductase SDR family member 7B [Homo sapiens] 96.7 9e-27
Q5R6U1 Dehydrogenase/reductase SDR family member 7B [Pongo abelii] 95.9 2e-26
D2WKD9 Farnesol dehydrogenase [Aedes aegypti] 94.0 2e-26
Q5HD73 Uncharacterized oxidoreductase SACOL2488 [Staphylococcus a... 93.2 3e-26
Q2FVD5 Uncharacterized oxidoreductase SAOUHSC_02778 [Staphylococc... 93.2 3e-26
Q2FE21 Uncharacterized oxidoreductase SAUSA300_2422 [Staphylococc... 93.2 3e-26
P0DKC6 11-beta-hydroxysteroid dehydrogenase 1B [Arabidopsis thali... 93.6 2e-25
P0DKC5 11-beta-hydroxysteroid dehydrogenase 1A [Arabidopsis thali... 93.6 2e-25
A6SSW9 Oxidoreductase BOA17 [Botryotinia fuckeliana (strain B05.10)] 91.7 3e-25
P87219 Sorbose reductase SOU1 [Candida albicans (strain SC5314 / ... 91.3 4e-25
P25145 Uncharacterized oxidoreductase Lmo0432 [Listeria monocytog... 90.1 7e-25
Q5RJY4 Dehydrogenase/reductase SDR family member 7B [Rattus norve... 91.3 8e-25
A0A1U8QWA2 Carboxylic acid reductase / Aldehyde reductase [Emeric... 91.3 4e-24
Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase [Homo sapiens] 86.7 1e-23
>P9WGR7 Uncharacterized oxidoreductase Rv0945 [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=253
Score = 232 bits (592), Expect = 5e-80
Identities = 119/244 (49%), Positives = 164/244 (67%), Gaps = 1/244 (0%)
Query 7 ILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHY-DVKIIAKSLDVTN 65
ILITGASSGLGAGMA+ FA +G +LA+CARR +RL LK EL + Y D+KI LDV +
Sbjct 10 ILITGASSGLGAGMARSFAAQGRDLALCARRTDRLTELKAELSQRYPDIKIAVAELDVND 69
Query 66 YDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALAQCEAAV 125
+++V +VF E G +DR+IVNAGIG+G R+G G N+ T ETN ++AL Q E A+
Sbjct 70 HERVPKVFAELSDEIGGIDRVIVNAGIGKGARLGSGKLWANKATIETNLVAALVQIETAL 129
Query 126 EIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVSTIFP 185
++F ++ SGHLV+ISS+ ++G+P + YAASKAGV L E +RAE PI+V+ + P
Sbjct 130 DMFNQRGSGHLVLISSVLGVKGVPGVKAAYAASKAGVRSLGESLRAEYAQRPIRVTVLEP 189
Query 186 GYIRTELNQGAKQLPFEIDEQTGARLLVKAIEKEPVKAYVPQWPWLPIGIAMKVLPLKLV 245
GYI +E+ + +D TG + LV AIE+EP +A VP WPW P+ M VLP +L
Sbjct 190 GYIESEMTAKSASTMLMVDNATGVKALVAAIEREPGRAAVPWWPWAPLVRLMWVLPPRLT 249
Query 246 NKLS 249
+ +
Sbjct 250 RRFA 253
>P9WGR6 Uncharacterized oxidoreductase MT0971 [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=253
Score = 232 bits (592), Expect = 5e-80
Identities = 119/244 (49%), Positives = 164/244 (67%), Gaps = 1/244 (0%)
Query 7 ILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHY-DVKIIAKSLDVTN 65
ILITGASSGLGAGMA+ FA +G +LA+CARR +RL LK EL + Y D+KI LDV +
Sbjct 10 ILITGASSGLGAGMARSFAAQGRDLALCARRTDRLTELKAELSQRYPDIKIAVAELDVND 69
Query 66 YDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALAQCEAAV 125
+++V +VF E G +DR+IVNAGIG+G R+G G N+ T ETN ++AL Q E A+
Sbjct 70 HERVPKVFAELSDEIGGIDRVIVNAGIGKGARLGSGKLWANKATIETNLVAALVQIETAL 129
Query 126 EIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVSTIFP 185
++F ++ SGHLV+ISS+ ++G+P + YAASKAGV L E +RAE PI+V+ + P
Sbjct 130 DMFNQRGSGHLVLISSVLGVKGVPGVKAAYAASKAGVRSLGESLRAEYAQRPIRVTVLEP 189
Query 186 GYIRTELNQGAKQLPFEIDEQTGARLLVKAIEKEPVKAYVPQWPWLPIGIAMKVLPLKLV 245
GYI +E+ + +D TG + LV AIE+EP +A VP WPW P+ M VLP +L
Sbjct 190 GYIESEMTAKSASTMLMVDNATGVKALVAAIEREPGRAAVPWWPWAPLVRLMWVLPPRLT 249
Query 246 NKLS 249
+ +
Sbjct 250 RRFA 253
>P25970 Uncharacterized oxidoreductase MXAN_5909 [Myxococcus xanthus
(strain DK1622)]
Length=253
Score = 122 bits (305), Expect = 6e-37
Identities = 79/238 (33%), Positives = 126/238 (53%), Gaps = 4/238 (2%)
Query 5 KTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLDVT 64
+T L+TGASSGLG G+A A++G + RRL +L+ L+ E + V + LDVT
Sbjct 7 RTALVTGASSGLGRGLALWLARRGVRVFAAGRRLPQLQALRDEAQAA-GVTVEPVELDVT 65
Query 65 NYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALAQCEAA 124
D E A + E G LD ++ NAG+G + ++ R +TN A A A
Sbjct 66 KADATLERIRALDAEAGGLDLVVANAGVGGTTNAKRLPWERVRGIIDTNVTGAAATLSAV 125
Query 125 VEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVSTIF 184
+ ++ GHLV +SS++ RGL H + Y+ASKA ++ E +R +L T ++V+ I+
Sbjct 126 LPQMVERKRGHLVGVSSLAGFRGLAGH-AAYSASKAFLSTFMESLRVDLRGTGVRVTCIY 184
Query 185 PGYIRTELNQGAK-QLPFEIDEQTGARLLVKAIEKEPVKAYVPQWPWLPIGIAMKVLP 241
PG++++EL +PF ++ L+ K I + + P +P +A KVLP
Sbjct 185 PGFVKSELTATNNFPMPFLMETHDAVELMGKGIVRGDAEVSFPWQLAVPTRMA-KVLP 241
>Q05016 NADP-dependent 3-hydroxy acid dehydrogenase [Saccharomyces
cerevisiae (strain ATCC 204508 / S288c)]
Length=267
Score = 102 bits (255), Expect = 2e-29
Identities = 66/194 (34%), Positives = 106/194 (55%), Gaps = 6/194 (3%)
Query 5 KTILITGASSGLGAGMAKEFAKKG---YNLAICARRLERLETLKTELERHY-DVKIIAKS 60
KT+LITGAS+G+G A E+ + L + ARRLE+LE LK +++ + + K+
Sbjct 14 KTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVHVAQ 73
Query 61 LDVTNYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGR-RVGKGHFDINRKTAETNFISALA 119
LD+T +++ QEF +D ++ NAG G RVG+ + + +TN + +
Sbjct 74 LDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVTALIN 133
Query 120 QCEAAVEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIK 179
+A + IF+ +NSG +V + S++ P S Y ASK V + +R ELI+T I+
Sbjct 134 ITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTG-SIYCASKFAVGAFTDSLRKELINTKIR 192
Query 180 VSTIFPGYIRTELN 193
V I PG + TE +
Sbjct 193 VILIAPGLVETEFS 206
>Q9P7B4 NADP-dependent 3-hydroxy acid dehydrogenase [Schizosaccharomyces
pombe (strain 972 / ATCC 24843)]
Length=259
Score = 101 bits (251), Expect = 5e-29
Identities = 63/191 (33%), Positives = 99/191 (52%), Gaps = 3/191 (2%)
Query 5 KTILITGASSGLGAGMAKEFAKKG-YNLAICARRLERLETLKTELERHYDVKIIAKSLDV 63
KTILITGASSG+G A E AK L + ARR +E + ELE Y+V ++ LDV
Sbjct 7 KTILITGASSGIGKSTAFEIAKVAKVKLILAARRFSTVEEIAKELESKYEVSVLPLKLDV 66
Query 64 TNYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGR-RVGKGHFDINRKTAETNFISALAQCE 122
++ + V + +EF +D +I NAG+ G +V + D TN + +A
Sbjct 67 SDLKSIPGVIESLPKEFADIDVLINNAGLALGTDKVIDLNIDDAVTMITTNVLGMMAMTR 126
Query 123 AAVEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVST 182
A + IF +N G ++ + S++ S Y ++K+ +A +R E IDT I++
Sbjct 127 AVLPIFYSKNKGDILNVGSIAGRESYVGG-SVYCSTKSALAQFTSALRKETIDTRIRIME 185
Query 183 IFPGYIRTELN 193
+ PG + TE +
Sbjct 186 VDPGLVETEFS 196
Score = 17.7 bits (34), Expect = 5.8
Identities = 14/48 (29%), Positives = 21/48 (44%), Gaps = 3/48 (6%)
Query 197 KQLPFEIDEQTGARLLVKAIEKEPVKAYVPQWPWLPIGIAMKVLPLKL 244
K FEI + +L++ A V+ + L + VLPLKL
Sbjct 20 KSTAFEIAKVAKVKLILAARRFSTVEEIAKE---LESKYEVSVLPLKL 64
>Q9Y140 Dehydrogenase/reductase SDR family protein 7-like [Drosophila
melanogaster]
Length=326
Score = 101 bits (252), Expect = 1e-28
Identities = 72/234 (31%), Positives = 116/234 (50%), Gaps = 21/234 (9%)
Query 5 KTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTEL-----ERHYDVKIIAK 59
K +LITGASSGLG +A F + G + + ARR + LE +K +L + Y ++
Sbjct 54 KVVLITGASSGLGESLAHVFYRAGCRVILAARRTQELERVKKDLLALDVDPAYPPTVL-- 111
Query 60 SLDVTNYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALA 119
LD+ + + E + Q+D +I N GI V D++ K N+ ++A
Sbjct 112 PLDLAELNSIPEFVTRVLAVYNQVDILINNGGISVRADVASTAVDVDLKVMVVNYFGSVA 171
Query 120 QCEAAVEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIK 179
+A + K+ SGH+ ISS+ +P+ + Y+ASK + A+ +RAE+ + I
Sbjct 172 LTKALLPSMVKRGSGHICFISSVQGKFAIPQR-AAYSASKHAMQAFADSLRAEVANKNIN 230
Query 180 VSTIFPGYIRTELN----QGAKQLPFEIDEQT---------GARLLVKAIEKEP 220
VS + PGYIRT+L+ G+ ++DE T R+L + KEP
Sbjct 231 VSCVSPGYIRTQLSLNALTGSGSSYGKVDETTAKGMSPDKLAERILQCILRKEP 284
>Q4A054 Uncharacterized oxidoreductase SSP0419 [Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM
20229 / NCIMB 8711 / NCTC 7292 / S-41)]
Length=234
Score = 97.8 bits (242), Expect = 7e-28
Identities = 54/189 (29%), Positives = 102/189 (54%), Gaps = 1/189 (1%)
Query 5 KTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLDVT 64
K ++TGASSG+GA +A+ A +G + + R RL + ++ + + +DVT
Sbjct 7 KVAVVTGASSGIGASIAETLANQGVKVVLTGRDESRLAEVAKRIQDNKQAVVETSIVDVT 66
Query 65 NYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALAQCEAA 124
+ ++V E+ +++FGQ+D ++ +AG+ + +G + + N L A
Sbjct 67 HKEEVTELVEKTKEKFGQIDILVNSAGLMLSSAITEGDVEAWEAMIDVNIKGTLYTINAV 126
Query 125 VEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVSTIF 184
+ Q+SGH++ I+S+S + K + Y+ASKA V + +G+ EL T ++V++I
Sbjct 127 LPSMLNQSSGHIINIASISGFE-VTKKSTLYSASKAAVHSITQGLEKELAKTGVRVTSIS 185
Query 185 PGYIRTELN 193
PG + T L+
Sbjct 186 PGMVDTPLS 194
>Q6IAN0 Dehydrogenase/reductase SDR family member 7B [Homo sapiens]
Length=325
Score = 96.7 bits (239), Expect = 9e-27
Identities = 64/195 (33%), Positives = 96/195 (49%), Gaps = 6/195 (3%)
Query 7 ILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAK-----SL 61
++ITGA+SGLG AK F G L +C R LE L EL + K+ +
Sbjct 55 VVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTF 114
Query 62 DVTNYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALAQC 121
D+T+ + Q FG +D ++ NAGI + D++++ ETN+ +A
Sbjct 115 DLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALT 174
Query 122 EAAVEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVS 181
+A + K+ GH+V ISS+ +P S YAASK + +RAE+ I+V+
Sbjct 175 KALLPSMIKRRQGHIVAISSIQGKMSIP-FRSAYAASKHATQAFFDCLRAEMEQYEIEVT 233
Query 182 TIFPGYIRTELNQGA 196
I PGYI T L+ A
Sbjct 234 VISPGYIHTNLSVNA 248
>Q5R6U1 Dehydrogenase/reductase SDR family member 7B [Pongo abelii]
Length=325
Score = 95.9 bits (237), Expect = 2e-26
Identities = 64/195 (33%), Positives = 96/195 (49%), Gaps = 6/195 (3%)
Query 7 ILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAK-----SL 61
++ITGA+SGLG AK F G L +C R LE L EL + K+ +
Sbjct 55 VVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTF 114
Query 62 DVTNYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALAQC 121
D+T+ + Q FG +D ++ NAGI + D++++ ETN+ +A
Sbjct 115 DLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALT 174
Query 122 EAAVEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVS 181
+A + K+ GH+V ISS+ +P S YAASK + +RAE+ I+V+
Sbjct 175 KALLPSMIKRRQGHIVAISSIQGKISIP-FRSAYAASKHATQAFFDCLRAEMEQYEIEVT 233
Query 182 TIFPGYIRTELNQGA 196
I PGYI T L+ A
Sbjct 234 VISPGYIHTNLSVNA 248
>D2WKD9 Farnesol dehydrogenase [Aedes aegypti]
Length=245
Score = 94.0 bits (232), Expect = 2e-26
Identities = 63/193 (33%), Positives = 107/193 (55%), Gaps = 5/193 (3%)
Query 5 KTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLDVT 64
K ++TGASSG+GA + + AK G + ARR+ER+E LK L ++ A DV+
Sbjct 7 KVAVVTGASSGIGAAITTDLAKAGMVVVGLARRVERVEALKANLPESAKPRLHAVKCDVS 66
Query 65 NYDQVFEVFNAFEQEFGQLDRIIVNAGI-GEGRRVGKGHFDINRKTAETNFISALAQCEA 123
+ + +VF E++FG +D ++ NAGI + +G + + R+ +TN + + +
Sbjct 67 KEEDITQVFKWVEKKFGGVDVLVNNAGILRQTDLLGTDNGQMLREVLDTNVMGLVLCSQK 126
Query 124 AVEIFRKQN-SGHLVVISSMSAMRGLP-KHLSTYAASKAGVAHLAEGIRAEL--IDTPIK 179
A + +K++ GH+V I+S+ + + Y ASK V + E +R EL + IK
Sbjct 127 AYQSMKKRSVDGHIVHINSVVGHKVFDFPQSNIYPASKHAVTAITETMRNELRNAGSRIK 186
Query 180 VSTIFPGYIRTEL 192
V++I PG +RTE+
Sbjct 187 VTSISPGVVRTEI 199
>Q5HD73 Uncharacterized oxidoreductase SACOL2488 [Staphylococcus
aureus (strain COL)]
Length=231
Score = 93.2 bits (230), Expect = 3e-26
Identities = 58/188 (31%), Positives = 101/188 (54%), Gaps = 4/188 (2%)
Query 5 KTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLDVT 64
K ++TGA SG+G +A ++G + + R E+L+ + +L + VK++ DVT
Sbjct 7 KVAVVTGAGSGIGEAIATLLHEEGAKVVLAGRNKEKLQNVANQLSQD-SVKVVPT--DVT 63
Query 65 NYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALAQCEAA 124
N ++V E+ +Q FG LD +I +AG ++ D + N L +AA
Sbjct 64 NKEEVDELIKIAQQTFGGLDIVINSAGQMLSSKITDYQVDEWDSMIDVNIKGTLYTAQAA 123
Query 125 VEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVSTIF 184
+ +Q+SGHL+ I+S+S + K + Y+A+KA V + +G+ EL T +KV++I
Sbjct 124 LPTMLEQSSGHLINIASISGFE-VTKSSTIYSATKAAVHTITQGLEKELAKTGVKVTSIS 182
Query 185 PGYIRTEL 192
PG + T +
Sbjct 183 PGMVDTAI 190
>Q2FVD5 Uncharacterized oxidoreductase SAOUHSC_02778 [Staphylococcus
aureus (strain NCTC 8325 / PS 47)]
Length=231
Score = 93.2 bits (230), Expect = 3e-26
Identities = 58/188 (31%), Positives = 101/188 (54%), Gaps = 4/188 (2%)
Query 5 KTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLDVT 64
K ++TGA SG+G +A ++G + + R E+L+ + +L + VK++ DVT
Sbjct 7 KVAVVTGAGSGIGEAIATLLHEEGAKVVLAGRNKEKLQNVANQLSQD-SVKVVPT--DVT 63
Query 65 NYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALAQCEAA 124
N ++V E+ +Q FG LD +I +AG ++ D + N L +AA
Sbjct 64 NKEEVDELIKIAQQTFGGLDIVINSAGQMLSSKITDYQVDEWDSMIDVNIKGTLYTAQAA 123
Query 125 VEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVSTIF 184
+ +Q+SGHL+ I+S+S + K + Y+A+KA V + +G+ EL T +KV++I
Sbjct 124 LPTMLEQSSGHLINIASISGFE-VTKSSTIYSATKAAVHTITQGLEKELAKTGVKVTSIS 182
Query 185 PGYIRTEL 192
PG + T +
Sbjct 183 PGMVDTAI 190
>Q2FE21 Uncharacterized oxidoreductase SAUSA300_2422 [Staphylococcus
aureus (strain USA300)]
Length=231
Score = 93.2 bits (230), Expect = 3e-26
Identities = 58/188 (31%), Positives = 101/188 (54%), Gaps = 4/188 (2%)
Query 5 KTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLDVT 64
K ++TGA SG+G +A ++G + + R E+L+ + +L + VK++ DVT
Sbjct 7 KVAVVTGAGSGIGEAIATLLHEEGAKVVLAGRNKEKLQNVANQLSQD-SVKVVPT--DVT 63
Query 65 NYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALAQCEAA 124
N ++V E+ +Q FG LD +I +AG ++ D + N L +AA
Sbjct 64 NKEEVDELIKIAQQTFGGLDIVINSAGQMLSSKITDYQVDEWDSMIDVNIKGTLYTAQAA 123
Query 125 VEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVSTIF 184
+ +Q+SGHL+ I+S+S + K + Y+A+KA V + +G+ EL T +KV++I
Sbjct 124 LPTMLEQSSGHLINIASISGFE-VTKSSTIYSATKAAVHTITQGLEKELAKTGVKVTSIS 182
Query 185 PGYIRTEL 192
PG + T +
Sbjct 183 PGMVDTAI 190
>P0DKC6 11-beta-hydroxysteroid dehydrogenase 1B [Arabidopsis thaliana]
Length=349
Score = 93.6 bits (231), Expect = 2e-25
Identities = 79/261 (30%), Positives = 129/261 (49%), Gaps = 26/261 (10%)
Query 5 KTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLDVT 64
K +LITGASSG+G +A E+A +G LA+ ARR RLE + ++ DV+
Sbjct 48 KVVLITGASSGIGEQLAYEYACRGACLALTARRKNRLEEVAEIARELGSPNVVTVHADVS 107
Query 65 NYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTA--ETNFISALAQCE 122
D + + FG+LD ++ NAG+ + + + DI R A +TNF ++
Sbjct 108 KPDDCRRIVDDTITHFGRLDHLVNNAGMTQ-ISMFENIEDITRTKAVLDTNFWGSVYTTR 166
Query 123 AAVEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVST 182
AA+ R Q++G +V +SS +A P+ +S Y ASKA + E +R EL + ++
Sbjct 167 AALPYLR-QSNGKIVAMSSSAAWLTAPR-MSFYNASKAALLSFFETMRIEL-GGDVHITI 223
Query 183 IFPGYIRTELNQG-----------------AKQLPFEIDEQTG-ARLLVKAIEKEPVKAY 224
+ PGYI +EL QG + PF + +G A+ +V + ++ + Y
Sbjct 224 VTPGYIESELTQGKYFSGEGELIVNQDMRDVQVGPFPVASASGCAKSIVNGVCRK--QRY 281
Query 225 VPQWPWLPIGIAMKVLPLKLV 245
V + W + KVL +L+
Sbjct 282 VTEPSWFKVTYLWKVLCPELI 302
Score = 19.2 bits (38), Expect = 2.0
Identities = 8/22 (36%), Positives = 13/22 (59%), Gaps = 0/22 (0%)
Query 169 IRAELIDTPIKVSTIFPGYIRT 190
+ ++D P ST++P IRT
Sbjct 322 LNKRIMDIPGVRSTLYPESIRT 343
>P0DKC5 11-beta-hydroxysteroid dehydrogenase 1A [Arabidopsis thaliana]
Length=349
Score = 93.6 bits (231), Expect = 2e-25
Identities = 79/261 (30%), Positives = 129/261 (49%), Gaps = 26/261 (10%)
Query 5 KTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLDVT 64
K +LITGASSG+G +A E+A +G LA+ ARR RLE + ++ DV+
Sbjct 48 KVVLITGASSGIGEQLAYEYACRGACLALTARRKNRLEEVAEIARELGSPNVVTVHADVS 107
Query 65 NYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTA--ETNFISALAQCE 122
D + + FG+LD ++ NAG+ + + + DI R A +TNF ++
Sbjct 108 KPDDCRRIVDDTITHFGRLDHLVNNAGMTQ-ISMFENIEDITRTKAVLDTNFWGSVYTTR 166
Query 123 AAVEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVST 182
AA+ R Q++G +V +SS +A P+ +S Y ASKA + E +R EL + ++
Sbjct 167 AALPYLR-QSNGKIVAMSSSAAWLTAPR-MSFYNASKAALLSFFETMRIEL-GGDVHITI 223
Query 183 IFPGYIRTELNQG-----------------AKQLPFEIDEQTG-ARLLVKAIEKEPVKAY 224
+ PGYI +EL QG + PF + +G A+ +V + ++ + Y
Sbjct 224 VTPGYIESELTQGKYFSGEGELIVNQDMRDVQVGPFPVASASGCAKSIVNGVCRK--QRY 281
Query 225 VPQWPWLPIGIAMKVLPLKLV 245
V + W + KVL +L+
Sbjct 282 VTEPSWFKVTYLWKVLCPELI 302
Score = 19.2 bits (38), Expect = 2.0
Identities = 8/22 (36%), Positives = 13/22 (59%), Gaps = 0/22 (0%)
Query 169 IRAELIDTPIKVSTIFPGYIRT 190
+ ++D P ST++P IRT
Sbjct 322 LNKRIMDIPGVRSTLYPESIRT 343
>A6SSW9 Oxidoreductase BOA17 [Botryotinia fuckeliana (strain B05.10)]
Length=274
Score = 91.7 bits (226), Expect = 3e-25
Identities = 60/198 (30%), Positives = 100/198 (51%), Gaps = 4/198 (2%)
Query 3 MTKTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLD 62
MTK ITG+S GLG +A+ G ++ AR+ E+L L + + ++ +LD
Sbjct 1 MTKIWFITGSSRGLGLAIAEAALNNGDSVIATARKPEQLTNLVNKFGKE---RVFPVALD 57
Query 63 VTNYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALAQCE 122
VT+ +QV + + ++FG++D +I NAG V D E N + + +
Sbjct 58 VTDNNQVLQAVKSGHEKFGRIDVVINNAGYANTAAVEDIDVDDFCAQVEANLMGVVYVSK 117
Query 123 AAVEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVST 182
A + I R+Q SGH+ +SS+ G P LS Y ++K V + + E+ IK++
Sbjct 118 AVLPILRQQKSGHIFQVSSLGGRIGAP-GLSAYQSAKWAVGGFSTVLAQEVASFGIKITV 176
Query 183 IFPGYIRTELNQGAKQLP 200
+ PG IRT+ + Q+P
Sbjct 177 LEPGGIRTDWAGSSMQVP 194
>P87219 Sorbose reductase SOU1 [Candida albicans (strain SC5314
/ ATCC MYA-2876)]
Length=281
Score = 91.3 bits (225), Expect = 4e-25
Identities = 58/191 (30%), Positives = 99/191 (52%), Gaps = 4/191 (2%)
Query 5 KTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLDVT 64
K +TG+S G+G +A+ FA+ G ++AI + + L Y VK A +VT
Sbjct 36 KVASVTGSSGGIGWAVAEAFAQAGADVAIWYNS-KPADAKAEYLTEKYGVKAKAYKCNVT 94
Query 65 NYDQVFEVFNAFEQEFGQLDRIIVNAGIG--EGRRVGKGHFDINRKTAETNFISALAQCE 122
+ + V +V N E++FG +D + NAG+ +G + +D +K + +
Sbjct 95 DPNDVSKVINEIEKDFGTIDIFVANAGVAWTDGPEIDVQGYDQWKKIVDCDLNGVYYCAH 154
Query 123 AAVEIFRKQNSGHLVVISSMSA-MRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVS 181
+IF+K SG L++ SSMS + +P+ + Y A+KA HLA+ + E +V+
Sbjct 155 TVGQIFKKNKSGSLIITSSMSGTIVNIPQLQAPYNAAKAACTHLAKSLSVEWASFGARVN 214
Query 182 TIFPGYIRTEL 192
+I PGYI T++
Sbjct 215 SISPGYILTDI 225
>P25145 Uncharacterized oxidoreductase Lmo0432 [Listeria monocytogenes
serovar 1/2a (strain ATCC BAA-679 / EGD-e)]
Length=248
Score = 90.1 bits (222), Expect = 7e-25
Identities = 63/190 (33%), Positives = 97/190 (51%), Gaps = 4/190 (2%)
Query 5 KTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLDVT 64
K I+ITGASSG+G A A+KG L + ARR+E+LE + ++ + I AK+ DVT
Sbjct 6 KVIIITGASSGIGKATALLLAEKGAKLVLAARRVEKLEKIVQTIKANSGEAIFAKT-DVT 64
Query 65 NYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALAQCEAA 124
+ ++ + +G++D I +NAGI + D + + N L A
Sbjct 65 KREDNKKLVELAIERYGKVDAIFLNAGIMPNSPLSALKEDEWEQMIDINIKGVLNGIAAV 124
Query 125 VEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELID--TPIKVST 182
+ F Q SGH++ SS++ ++ P + Y A+K V L E +R E T I+ T
Sbjct 125 LPSFIAQKSGHIIATSSVAGLKAYPGG-AVYGATKWAVRDLMEVLRMESAQEGTNIRTVT 183
Query 183 IFPGYIRTEL 192
I+P I TEL
Sbjct 184 IYPAAINTEL 193
>Q5RJY4 Dehydrogenase/reductase SDR family member 7B [Rattus norvegicus]
Length=325
Score = 91.3 bits (225), Expect = 8e-25
Identities = 61/198 (31%), Positives = 97/198 (49%), Gaps = 12/198 (6%)
Query 7 ILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTEL--------ERHYDVKIIA 58
+++TGA+SGLG A+ F G + +C R ++ LE EL + H +
Sbjct 55 VVVTGATSGLGKECARVFHAAGAKVVLCGRNVKALEEFTRELADSSSSQGQTHQPCVV-- 112
Query 59 KSLDVTNYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISAL 118
+ D+ + + Q FG +D +I NAGI + D++RK E N+ +
Sbjct 113 -TFDLADPGAIAPAAAEILQCFGYVDILINNAGISYRGAISDTIVDVDRKVMEINYFGPV 171
Query 119 AQCEAAVEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPI 178
A +A + ++ GH+V ISS+ +P S YAASK + +RAE+ D+ I
Sbjct 172 ALTKALLPSMVERKRGHIVAISSIQGKISIP-FRSAYAASKHATQAFFDCLRAEMKDSDI 230
Query 179 KVSTIFPGYIRTELNQGA 196
+V+ I PGYI T L+ A
Sbjct 231 EVTVISPGYIHTNLSVNA 248
>A0A1U8QWA2 Carboxylic acid reductase / Aldehyde reductase [Emericella
nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46
/ NRRL 194 / M139)]
Length=1270
Score = 91.3 bits (225), Expect = 4e-24
Identities = 60/188 (32%), Positives = 97/188 (52%), Gaps = 2/188 (1%)
Query 5 KTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLDVT 64
K ++TGASSG+GA +A A++G ++A+ ARRL+ LE+LK +L VK++ DVT
Sbjct 1030 KVAVVTGASSGIGAAVATALAREGAHVALGARRLDALESLKEKLSAS-GVKVVTCKTDVT 1088
Query 65 NYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALAQCEAA 124
+ QV + A +E G +D ++ AG+ + D +T + N L +
Sbjct 1089 DRKQVEGLVKAATEELGPVDILVACAGVMYFTMMANTQMDEWERTVDVNCKGILNSLAST 1148
Query 125 VEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVSTIF 184
V + GH+V ISS + + P L Y+ASK V + +R E ++V+ +
Sbjct 1149 VPGMLARGKGHVVAISSDAGRKVFP-GLGVYSASKFFVEATLQALRLETAGQGLRVTAVQ 1207
Query 185 PGYIRTEL 192
PG T+L
Sbjct 1208 PGNTATDL 1215
Score = 26.2 bits (56), Expect = 0.014
Identities = 14/42 (33%), Positives = 20/42 (48%), Gaps = 0/42 (0%)
Query 1 MTMTKTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLE 42
+T KT+L+TG + LGA + K+ IC R E
Sbjct 639 LTDAKTVLLTGVTGFLGAFLLKDLVDSTSAHIICLVRFNEPE 680
>Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase [Homo sapiens]
Length=237
Score = 86.7 bits (213), Expect = 1e-23
Identities = 52/196 (27%), Positives = 96/196 (49%), Gaps = 5/196 (3%)
Query 3 MTKTILITGASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLD 62
M K + G S G+G +A+ A+KGY LA+ AR LE + +L + +A S D
Sbjct 1 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH----LAFSCD 56
Query 63 VTNYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGHFDINRKTAETNFISALAQCE 122
V V F E+ G+++ ++ AGI + + + TN + ++ C+
Sbjct 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116
Query 123 AAVEIFRKQNSGHLVVISSMSAMRGLPKHLSTYAASKAGVAHLAEGIRAELIDTPIKVST 182
AA+ +Q G +V + S+ ++G S Y+ASK G+ + + E+ I+V+
Sbjct 117 AAMRTMIQQQGGSIVNVGSIVGLKG-NSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175
Query 183 IFPGYIRTELNQGAKQ 198
+ PG++ T++ + K+
Sbjct 176 VAPGFVHTDMTKDLKE 191
Score = 22.7 bits (47), Expect = 0.14
Identities = 15/65 (23%), Positives = 27/65 (42%), Gaps = 5/65 (8%)
Query 11 GASSGLGAGMAKEFAKKGYNLAICARRLERLETLKTELERHYDVKIIAKSLDVTNYDQVF 70
G G +AKE A+K + + A + K E H + K++ + + +
Sbjct 153 GGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKDLKEEH-----LKKNIPLGRFGETI 207
Query 71 EVFNA 75
EV +A
Sbjct 208 EVAHA 212
Lambda K H a alpha
0.322 0.137 0.391 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1183200
Database: 22caf3ea454ab4f03243fc67387dccbe.SwissProt.fasta
Posted date: Jun 2, 2024 10:33 AM
Number of letters in database: 6,766
Number of sequences in database: 21
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
Loading
Data ...
