BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: d019ba3116564757946aec18815a6bb4.SwissProt.fasta
22 sequences; 5,214 total letters
Query= ACIAD1903
Length=308
Score E
Sequences producing significant alignments: (Bits) Value
P59014 Cyclic pyranopterin monophosphate synthase / Molybdenum co... 181 2e-58
Q56208 Cyclic pyranopterin monophosphate synthase / Molybdenum co... 142 1e-43
B5FCP1 Cyclic pyranopterin monophosphate synthase [Aliivibrio fis... 127 1e-39
Q5E6B0 Cyclic pyranopterin monophosphate synthase [Aliivibrio fis... 127 1e-39
B9L0K8 Cyclic pyranopterin monophosphate synthase [Thermomicrobiu... 127 1e-39
A9BQ97 Cyclic pyranopterin monophosphate synthase [Delftia acidov... 127 2e-39
B6EGI3 Cyclic pyranopterin monophosphate synthase [Aliivibrio sal... 126 3e-39
A7MVD3 Cyclic pyranopterin monophosphate synthase [Vibrio campbel... 125 1e-38
Q87MY2 Cyclic pyranopterin monophosphate synthase [Vibrio parahae... 125 1e-38
Q6LT40 Cyclic pyranopterin monophosphate synthase [Photobacterium... 124 2e-38
B0BNX3 Cyclic pyranopterin monophosphate synthase [Actinobacillus... 122 8e-38
B3GXC6 Cyclic pyranopterin monophosphate synthase [Actinobacillus... 122 8e-38
A3N055 Cyclic pyranopterin monophosphate synthase [Actinobacillus... 122 8e-38
Q93KD0 Cyclic pyranopterin monophosphate synthase [Peptoclostridi... 115 4e-35
P9WJR7 Cyclic pyranopterin monophosphate synthase 2 [Mycobacteriu... 113 5e-34
P0A738 Cyclic pyranopterin monophosphate synthase [Escherichia co... 112 1e-33
P94328 Cyclic pyranopterin monophosphate synthase [Bradyrhizobium... 111 3e-33
P9WJR9 Cyclic pyranopterin monophosphate synthase 1 [Mycobacteriu... 108 5e-32
Q9NZB8 GTP 3',8-cyclase / Cyclic pyranopterin monophosphate synth... 112 4e-31
Q8IQF1 GTP 3',8-cyclase / Cyclic pyranopterin monophosphate synth... 109 4e-30
Q5RKZ7 GTP 3',8-cyclase / Cyclic pyranopterin monophosphate synth... 106 5e-29
Q2FVX9 Cyclic pyranopterin monophosphate synthase [Staphylococcus... 96.3 1e-27
>P59014 Cyclic pyranopterin monophosphate synthase / Molybdenum
cofactor biosynthesis protein B [Chlorobaculum tepidum (strain
ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)]
Length=312
Score = 181 bits (458), Expect = 2e-58
Identities = 112/303 (37%), Positives = 166/303 (55%), Gaps = 6/303 (2%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V KP + R A A + P I LLR KG+ L +IAGI AAK+T LIP
Sbjct 14 MADVSGKPPTRRKACASGRIVMLPETIALLRRKELPKGNVLAAAKIAGIQAAKQTSTLIP 73
Query 61 LCHPLPIYRAEVEYELHENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHCEP 120
LCH L + ++E+E+ ++ + I TV T TGVEMEAL A S+A LT+YDM K
Sbjct 74 LCHQLNLSWIDIEFEIGDDSIGIAATVITRESTGVEMEALAAVSVAALTIYDMCK--AVD 131
Query 121 EDLVLDQCKLLKKKGGKSHFKRTLRQAVSAAVIVLSDTVASGKKPDTAGKSVVDTLNEAG 180
+ + + +L K GGKS A++V+SD++A+G D +G + + L +AG
Sbjct 132 KTMEISAIRLDHKTGGKS---SAAEYHPRTAILVMSDSIAAGTATDHSGAILREGLQKAG 188
Query 181 FTPIHYQILPDESDQLKDLV-LELTQSYACIITVGGTGIGKRDITVDTLEPLLERKLDGL 239
I PDE ++ V + + I+T GGTG+G RD+ +DTL P R+L G+
Sbjct 189 CAVEALTITPDEPVEIAATVEAWIGEGIEFIVTSGGTGLGPRDLAIDTLAPKFTRRLPGV 248
Query 240 MEAARAFGQRRTPYAAMSRGVAGFIDRSLIMTLPGSRGGASESMAALLPAIVHIFDVCRD 299
+ +GQ +T A +SR AG I ++++ LPGS A +++ L+PAI H F + +
Sbjct 249 EQELLRWGQTKTRTAMLSRLAAGVIGNTVVVCLPGSTSAAKDALEVLVPAIFHAFPMLKG 308
Query 300 LPH 302
H
Sbjct 309 DGH 311
>Q56208 Cyclic pyranopterin monophosphate synthase / Molybdenum
cofactor biosynthesis protein B [Synechococcus elongatus (strain
ATCC 33912 / PCC 7942 / FACHB-805)]
Length=319
Score = 142 bits (359), Expect = 1e-43
Identities = 101/316 (32%), Positives = 151/316 (48%), Gaps = 16/316 (5%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +VG K + R A A+ + P + + G KGD ++AGI AKRT +L+P
Sbjct 1 MIDVGDKAVTERTARAEGWIRLAPEVYQRVTQGQLPKGDGFLLAQVAGIQGAKRTADLLP 60
Query 61 LCHPLPIYRAEVEYE--LHENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCHPLPI +++ + + + V T G TGVEMEAL A S A L LYD+ K
Sbjct 61 LCHPLPIEGVKIDCQPLADSQTIRVEARVRTTGKTGVEMEALAAVSAALLCLYDLTKMFD 120
Query 119 EPEDLVLDQCKLLKKKGGKS-HFKRT----------LRQAVSAAVIVLSDTVASGKKPDT 167
+ + LL+K GGKS H++R V A VI +SD VA+ + D
Sbjct 121 ATAE--IGGIGLLEKTGGKSGHWQRPAIAPDVAPTGALAGVFATVITVSDRVAADQAEDR 178
Query 168 AGKSVVDTLNEAGFTPIHYQILPDESDQLKDLV-LELTQSYACIITVGGTGIGKRDITVD 226
+G + + L + T + DE ++ + + Q A I+ GGTG+G RD T +
Sbjct 179 SGPLIQNWLTDQAATIATATCVADEPALIQAAIQAAIAQGSALILLTGGTGLGPRDRTPE 238
Query 227 TLEPLLERKLDGLMEAARAFGQRRTPYAAMSRGVAGFIDRSLIMTLPGSRGGASESMAAL 286
+ L + G+ EA R G+ T +SR ++ S ++ LPGS S +A L
Sbjct 239 AIADLGAIPVPGIGEALRQAGRSETVMTWLSRSGGWMLEGSFVIALPGSSRAVSSGLAML 298
Query 287 LPAIVHIFDVCRDLPH 302
P + H + + H
Sbjct 299 QPLLPHSLAILKGADH 314
>B5FCP1 Cyclic pyranopterin monophosphate synthase [Aliivibrio
fischeri (strain MJ11)]
Length=159
Score = 127 bits (320), Expect = 1e-39
Identities = 73/144 (51%), Positives = 96/144 (67%), Gaps = 5/144 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V K E+ R A A+A ++ P +EL+ +G+ KGD T RIAGI AAK+T +LIP
Sbjct 15 MVDVSAKQETVREARAEAFVHMAPETLELIVSGSHHKGDVFATARIAGIQAAKKTWDLIP 74
Query 61 LCHPLPIYRAEVEYEL--HENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCHPL + + EV+ E EN V I + + G TGVEMEALTAAS+A LT+YDM K
Sbjct 75 LCHPLLLSKVEVQLEAIEAENMVRIESVCKLAGKTGVEMEALTAASVAALTIYDMCK--A 132
Query 119 EPEDLVLDQCKLLKKKGGKS-HFK 141
+D+V+ Q +LL+K GGKS HFK
Sbjct 133 VQKDMVIGQVRLLEKTGGKSGHFK 156
Score = 21.6 bits (44), Expect = 0.28
Identities = 9/30 (30%), Positives = 16/30 (53%), Gaps = 0/30 (0%)
Query 269 IMTLPGSRGGASESMAALLPAIVHIFDVCR 298
+ L G G E++ A A + I+D+C+
Sbjct 102 VCKLAGKTGVEMEALTAASVAALTIYDMCK 131
>Q5E6B0 Cyclic pyranopterin monophosphate synthase [Aliivibrio
fischeri (strain ATCC 700601 / ES114)]
Length=159
Score = 127 bits (320), Expect = 1e-39
Identities = 73/144 (51%), Positives = 96/144 (67%), Gaps = 5/144 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V K E+ R A A+A ++ P +EL+ +G+ KGD T RIAGI AAK+T +LIP
Sbjct 15 MVDVSAKQETVREARAEAFVHMAPETLELIVSGSHHKGDVFATARIAGIQAAKKTWDLIP 74
Query 61 LCHPLPIYRAEVEYEL--HENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCHPL + + EV+ E EN V I + + G TGVEMEALTAAS+A LT+YDM K
Sbjct 75 LCHPLLLSKVEVQLEAIEAENMVRIESVCKLAGKTGVEMEALTAASVAALTIYDMCK--A 132
Query 119 EPEDLVLDQCKLLKKKGGKS-HFK 141
+D+V+ Q +LL+K GGKS HFK
Sbjct 133 VQKDMVIGQVRLLEKTGGKSGHFK 156
Score = 21.6 bits (44), Expect = 0.28
Identities = 9/30 (30%), Positives = 16/30 (53%), Gaps = 0/30 (0%)
Query 269 IMTLPGSRGGASESMAALLPAIVHIFDVCR 298
+ L G G E++ A A + I+D+C+
Sbjct 102 VCKLAGKTGVEMEALTAASVAALTIYDMCK 131
>B9L0K8 Cyclic pyranopterin monophosphate synthase [Thermomicrobium
roseum (strain ATCC 27502 / DSM 5159 / P-2)]
Length=166
Score = 127 bits (320), Expect = 1e-39
Identities = 67/140 (48%), Positives = 94/140 (67%), Gaps = 4/140 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V KPE++R+A A+ + P ++L+R G KGD L R+AGI+AAKRT ELIP
Sbjct 15 MVDVAEKPETHRVAVARGRVSLRPETLQLVREGRAAKGDVLAVARVAGIMAAKRTAELIP 74
Query 61 LCHPLPIYRAEVEYELHE--NFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCHPLP+ + EV+ +E +EI VET+ TGVEMEALTA ++A LT+YDMLK
Sbjct 75 LCHPLPLTKVEVDVRTNEQDTCLEIEARVETVSRTGVEMEALTAVAVAALTVYDMLK--A 132
Query 119 EPEDLVLDQCKLLKKKGGKS 138
+ +D+ +L++K GG+S
Sbjct 133 VDRGMTIDRIQLIEKAGGRS 152
>A9BQ97 Cyclic pyranopterin monophosphate synthase [Delftia acidovorans
(strain DSM 14801 / SPH-1)]
Length=156
Score = 127 bits (318), Expect = 2e-39
Identities = 67/144 (47%), Positives = 98/144 (68%), Gaps = 4/144 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +VG KP ++RIA A+ + P + ++++G +KGD L RIAGI+AAK+T +LIP
Sbjct 15 MVDVGAKPATHRIAVAEGRIIMQPATLAIIQSGTAKKGDVLGIARIAGIMAAKKTSDLIP 74
Query 61 LCHPLPIYRAEVEYELHENF--VEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCHPL + R VE++L + V + TVET+GPTGVEMEALTA +A LT+YDM K
Sbjct 75 LCHPLALTRVAVEFDLLSDVSSVRCVATVETVGPTGVEMEALTAVQVALLTVYDMCK--A 132
Query 119 EPEDLVLDQCKLLKKKGGKSHFKR 142
+ +V++ ++L+K GGK++ R
Sbjct 133 VDKGMVMEGIRVLEKLGGKTNPSR 156
Score = 21.2 bits (43), Expect = 0.37
Identities = 7/25 (28%), Positives = 16/25 (64%), Gaps = 0/25 (0%)
Query 274 GSRGGASESMAALLPAIVHIFDVCR 298
G G E++ A+ A++ ++D+C+
Sbjct 107 GPTGVEMEALTAVQVALLTVYDMCK 131
Score = 17.7 bits (34), Expect = 5.1
Identities = 11/33 (33%), Positives = 16/33 (48%), Gaps = 2/33 (6%)
Query 192 ESDQLKDLVLELTQSYACIITVGGTGIGKRDIT 224
E D L D+ + A + TVG TG+ +T
Sbjct 87 EFDLLSDV--SSVRCVATVETVGPTGVEMEALT 117
>B6EGI3 Cyclic pyranopterin monophosphate synthase [Aliivibrio
salmonicida (strain LFI1238)]
Length=159
Score = 126 bits (317), Expect = 3e-39
Identities = 72/144 (50%), Positives = 96/144 (67%), Gaps = 5/144 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V K E+ R A A+A ++ P ++L+ +G+ KGD T RIAGI AAK+T +LIP
Sbjct 15 MVDVSAKQETVREARAEAFVHMAPETLKLIVSGSHHKGDVFATARIAGIQAAKKTWDLIP 74
Query 61 LCHPLPIYRAEVEYEL--HENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCHPL + + EV+ E EN V I + + G TGVEMEALTAAS+A LT+YDM K
Sbjct 75 LCHPLLLTKVEVQLEAIEAENMVRIESVCKLTGKTGVEMEALTAASVAALTIYDMCK--A 132
Query 119 EPEDLVLDQCKLLKKKGGKS-HFK 141
+D+V+ Q +LL+K GGKS HFK
Sbjct 133 VQKDMVISQVRLLEKTGGKSGHFK 156
Score = 21.6 bits (44), Expect = 0.28
Identities = 9/30 (30%), Positives = 16/30 (53%), Gaps = 0/30 (0%)
Query 269 IMTLPGSRGGASESMAALLPAIVHIFDVCR 298
+ L G G E++ A A + I+D+C+
Sbjct 102 VCKLTGKTGVEMEALTAASVAALTIYDMCK 131
>A7MVD3 Cyclic pyranopterin monophosphate synthase [Vibrio campbellii
(strain ATCC BAA-1116)]
Length=158
Score = 125 bits (313), Expect = 1e-38
Identities = 72/144 (50%), Positives = 95/144 (66%), Gaps = 5/144 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V K E+ R A A+A ++ P ++L+ +G KGD T RIAGI AAK+T +LIP
Sbjct 15 MVDVSAKAETVREARAEAFVHMAPETLQLIVSGQHHKGDVFATARIAGIQAAKKTWDLIP 74
Query 61 LCHPLPIYRAEVEYEL--HENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCHPL + + EV+ E EN V I + + G TGVEMEALTAAS+A LT+YDM K
Sbjct 75 LCHPLLLSKVEVQLEAIEAENKVRIESVCKLAGKTGVEMEALTAASVAALTIYDMCK--A 132
Query 119 EPEDLVLDQCKLLKKKGGKS-HFK 141
+D+V+ Q +LL+K GGKS HFK
Sbjct 133 VQKDMVIGQVRLLEKTGGKSGHFK 156
Score = 21.6 bits (44), Expect = 0.28
Identities = 9/30 (30%), Positives = 16/30 (53%), Gaps = 0/30 (0%)
Query 269 IMTLPGSRGGASESMAALLPAIVHIFDVCR 298
+ L G G E++ A A + I+D+C+
Sbjct 102 VCKLAGKTGVEMEALTAASVAALTIYDMCK 131
>Q87MY2 Cyclic pyranopterin monophosphate synthase [Vibrio parahaemolyticus
serotype O3:K6 (strain RIMD 2210633)]
Length=159
Score = 125 bits (313), Expect = 1e-38
Identities = 72/144 (50%), Positives = 95/144 (66%), Gaps = 5/144 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V K E+ R A A+A ++ P ++L+ +G KGD T RIAGI AAK+T +LIP
Sbjct 15 MVDVSAKAETVREARAEAFVHMAPETLQLIVSGQHHKGDVFATARIAGIQAAKKTWDLIP 74
Query 61 LCHPLPIYRAEVEYEL--HENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCHPL + + EV+ E EN V I + + G TGVEMEALTAAS+A LT+YDM K
Sbjct 75 LCHPLLLSKVEVQLEAIEAENKVRIESVCKLAGKTGVEMEALTAASVAALTIYDMCK--A 132
Query 119 EPEDLVLDQCKLLKKKGGKS-HFK 141
+D+V+ Q +LL+K GGKS HFK
Sbjct 133 VQKDMVIGQVRLLEKTGGKSGHFK 156
Score = 21.6 bits (44), Expect = 0.28
Identities = 9/30 (30%), Positives = 16/30 (53%), Gaps = 0/30 (0%)
Query 269 IMTLPGSRGGASESMAALLPAIVHIFDVCR 298
+ L G G E++ A A + I+D+C+
Sbjct 102 VCKLAGKTGVEMEALTAASVAALTIYDMCK 131
>Q6LT40 Cyclic pyranopterin monophosphate synthase [Photobacterium
profundum (strain SS9)]
Length=165
Score = 124 bits (312), Expect = 2e-38
Identities = 72/149 (48%), Positives = 94/149 (63%), Gaps = 10/149 (7%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V K E+ R A A+A ++ P +EL+ +G KGD T RIAGI AAK+T +LIP
Sbjct 16 MVDVSAKAETVREARAEAFVHMAPETLELIVSGQNHKGDVFATARIAGIQAAKKTWDLIP 75
Query 61 LCHPLPIYRAEVEYEL-------HENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDM 113
LCHPL + + EV+ E N V I + + G TGVEMEALTAAS+A LT+YDM
Sbjct 76 LCHPLLLSKVEVQLEAIPAANENETNMVRIESCCKLAGKTGVEMEALTAASVAALTIYDM 135
Query 114 LKPHCEPEDLVLDQCKLLKKKGGKS-HFK 141
K +D+V+ Q +LL+K GGKS HFK
Sbjct 136 CK--AVQKDMVISQVRLLEKTGGKSGHFK 162
Score = 22.3 bits (46), Expect = 0.16
Identities = 17/69 (25%), Positives = 28/69 (41%), Gaps = 10/69 (14%)
Query 230 PLLERKLDGLMEAARAFGQRRTPYAAMSRGVAGFIDRSLIMTLPGSRGGASESMAALLPA 289
PLL K++ +EA A + T + L G G E++ A A
Sbjct 79 PLLLSKVEVQLEAIPAANENETNMVRIES----------CCKLAGKTGVEMEALTAASVA 128
Query 290 IVHIFDVCR 298
+ I+D+C+
Sbjct 129 ALTIYDMCK 137
>B0BNX3 Cyclic pyranopterin monophosphate synthase [Actinobacillus
pleuropneumoniae serotype 3 (strain JL03)]
Length=158
Score = 122 bits (307), Expect = 8e-38
Identities = 69/140 (49%), Positives = 91/140 (65%), Gaps = 4/140 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V MK E+ R+A A+A + ++++ +GN KGD T RIAGI AAKRT ELIP
Sbjct 15 MVDVSMKQETVRVARAEAFVSMNAETLQMIISGNHHKGDVFATARIAGIQAAKRTWELIP 74
Query 61 LCHPLPIYRAEVEYEL--HENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCHPL + + EV+ E N V I + + G TGVEMEALTAAS+A LT+YDM K
Sbjct 75 LCHPLLLSKVEVQLEALPETNQVRIESLCKLTGKTGVEMEALTAASVAALTIYDMCK--A 132
Query 119 EPEDLVLDQCKLLKKKGGKS 138
+D+V++ +LL K GGKS
Sbjct 133 VQKDMVIENVRLLHKSGGKS 152
Score = 21.2 bits (43), Expect = 0.38
Identities = 9/27 (33%), Positives = 15/27 (56%), Gaps = 0/27 (0%)
Query 272 LPGSRGGASESMAALLPAIVHIFDVCR 298
L G G E++ A A + I+D+C+
Sbjct 105 LTGKTGVEMEALTAASVAALTIYDMCK 131
>B3GXC6 Cyclic pyranopterin monophosphate synthase [Actinobacillus
pleuropneumoniae serotype 7 (strain AP76)]
Length=158
Score = 122 bits (307), Expect = 8e-38
Identities = 69/140 (49%), Positives = 91/140 (65%), Gaps = 4/140 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V MK E+ R+A A+A + ++++ +GN KGD T RIAGI AAKRT ELIP
Sbjct 15 MVDVSMKQETVRVARAEAFVSMNAETLQMIISGNHHKGDVFATARIAGIQAAKRTWELIP 74
Query 61 LCHPLPIYRAEVEYEL--HENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCHPL + + EV+ E N V I + + G TGVEMEALTAAS+A LT+YDM K
Sbjct 75 LCHPLLLSKVEVQLEALPETNQVRIESLCKLTGKTGVEMEALTAASVAALTIYDMCK--A 132
Query 119 EPEDLVLDQCKLLKKKGGKS 138
+D+V++ +LL K GGKS
Sbjct 133 VQKDMVIENVRLLHKSGGKS 152
Score = 21.2 bits (43), Expect = 0.38
Identities = 9/27 (33%), Positives = 15/27 (56%), Gaps = 0/27 (0%)
Query 272 LPGSRGGASESMAALLPAIVHIFDVCR 298
L G G E++ A A + I+D+C+
Sbjct 105 LTGKTGVEMEALTAASVAALTIYDMCK 131
>A3N055 Cyclic pyranopterin monophosphate synthase [Actinobacillus
pleuropneumoniae serotype 5b (strain L20)]
Length=158
Score = 122 bits (307), Expect = 8e-38
Identities = 69/140 (49%), Positives = 91/140 (65%), Gaps = 4/140 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V MK E+ R+A A+A + ++++ +GN KGD T RIAGI AAKRT ELIP
Sbjct 15 MVDVSMKQETVRVARAEAFVSMNAETLQMIISGNHHKGDVFATARIAGIQAAKRTWELIP 74
Query 61 LCHPLPIYRAEVEYEL--HENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCHPL + + EV+ E N V I + + G TGVEMEALTAAS+A LT+YDM K
Sbjct 75 LCHPLLLSKVEVQLEALPETNQVRIESLCKLTGKTGVEMEALTAASVAALTIYDMCK--A 132
Query 119 EPEDLVLDQCKLLKKKGGKS 138
+D+V++ +LL K GGKS
Sbjct 133 VQKDMVIENVRLLHKSGGKS 152
Score = 21.2 bits (43), Expect = 0.38
Identities = 9/27 (33%), Positives = 15/27 (56%), Gaps = 0/27 (0%)
Query 272 LPGSRGGASESMAALLPAIVHIFDVCR 298
L G G E++ A A + I+D+C+
Sbjct 105 LTGKTGVEMEALTAASVAALTIYDMCK 131
>Q93KD0 Cyclic pyranopterin monophosphate synthase [Peptoclostridium
acidaminophilum]
Length=157
Score = 115 bits (289), Expect = 4e-35
Identities = 59/138 (43%), Positives = 87/138 (63%), Gaps = 2/138 (1%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +VG K ++ R A A+A + I ++R G +KGD L ++ GI+ AKRT ++IP
Sbjct 14 MVDVGGKDDTNREATARACIKMNRETISMIRDGQMKKGDVLSVAQVGGIMGAKRTSDIIP 73
Query 61 LCHPLPIYRAEVEYELHENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHCEP 120
+CH + I ++E++LHE +EI +T G TG+EMEALTA S+A LT+YDM K
Sbjct 74 MCHNIFISGVDIEFKLHEEEIEISAVAKTRGKTGIEMEALTAVSVAALTIYDMCK--AVD 131
Query 121 EDLVLDQCKLLKKKGGKS 138
+ +V+ L+KK GGKS
Sbjct 132 KGMVISDIMLIKKTGGKS 149
Score = 21.9 bits (45), Expect = 0.21
Identities = 10/35 (29%), Positives = 19/35 (54%), Gaps = 0/35 (0%)
Query 264 IDRSLIMTLPGSRGGASESMAALLPAIVHIFDVCR 298
I+ S + G G E++ A+ A + I+D+C+
Sbjct 94 IEISAVAKTRGKTGIEMEALTAVSVAALTIYDMCK 128
>P9WJR7 Cyclic pyranopterin monophosphate synthase 2 [Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=167
Score = 113 bits (282), Expect = 5e-34
Identities = 63/137 (46%), Positives = 87/137 (64%), Gaps = 2/137 (1%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M ++ K + R A A IL + L+ TG KGDAL T R+AGI+AAKRT +LIP
Sbjct 26 MVDITEKATTKRTAVAAGILRTSAQVVALISTGGLPKGDALATARVAGIMAAKRTSDLIP 85
Query 61 LCHPLPIYRAEVEYELHENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHCEP 120
LCH L + +V++ + + +EI TV + TGVEMEALTA S+A LTLYDM+K +P
Sbjct 86 LCHQLALTGVDVDFTVGQLDIEITATVRSTDRTGVEMEALTAVSVAALTLYDMIKA-VDP 144
Query 121 EDLVLDQCKLLKKKGGK 137
L+ D ++L K+GG+
Sbjct 145 GALI-DDIRVLHKEGGR 160
>P0A738 Cyclic pyranopterin monophosphate synthase [Escherichia
coli (strain K12)]
Length=161
Score = 112 bits (279), Expect = 1e-33
Identities = 67/140 (48%), Positives = 84/140 (60%), Gaps = 4/140 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V K E+ R A A+A + + ++ G KGD T RIAGI AAKRT +LIP
Sbjct 15 MVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIP 74
Query 61 LCHPLPIYRAEV--EYELHENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCHPL + + EV + E N V I T G TGVEMEALTAAS+A LT+YDM K
Sbjct 75 LCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCK--A 132
Query 119 EPEDLVLDQCKLLKKKGGKS 138
+D+V+ +LL K GGKS
Sbjct 133 VQKDMVIGPVRLLAKSGGKS 152
Score = 21.2 bits (43), Expect = 0.38
Identities = 9/27 (33%), Positives = 15/27 (56%), Gaps = 0/27 (0%)
Query 272 LPGSRGGASESMAALLPAIVHIFDVCR 298
L G G E++ A A + I+D+C+
Sbjct 105 LTGKTGVEMEALTAASVAALTIYDMCK 131
>P94328 Cyclic pyranopterin monophosphate synthase [Bradyrhizobium
diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628
/ NBRC 14792 / USDA 110)]
Length=172
Score = 111 bits (277), Expect = 3e-33
Identities = 65/144 (45%), Positives = 91/144 (63%), Gaps = 5/144 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V KP + R+A A+ + ++L+ +GN +KGD L T RIAGI+AAKRT ELIP
Sbjct 30 MVDVSDKPATERLAVAEGRVLMTRATLDLIVSGNAKKGDVLGTARIAGIMAAKRTSELIP 89
Query 61 LCHPLPIYRAEVEYELHENFVEIL--TTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCHPL + + V+ E L +V+ GPTGVEMEALTA S+A LT+YDM+K
Sbjct 90 LCHPLALSKVTVDIEPDAKLPGCLVRASVKVTGPTGVEMEALTAVSVACLTIYDMIK--A 147
Query 119 EPEDLVLDQCKLLKKKGGKS-HFK 141
+ ++ L++K GGKS H++
Sbjct 148 VERGVRIEGIHLVEKLGGKSGHYR 171
>P9WJR9 Cyclic pyranopterin monophosphate synthase 1 [Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=170
Score = 108 bits (269), Expect = 5e-32
Identities = 62/139 (45%), Positives = 83/139 (60%), Gaps = 3/139 (2%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V KP + R+A+A ++ P + ++ G KGD + RIAGI AAKRT +LIP
Sbjct 19 MVDVSEKPVTLRVAKASGLVIMKPSTLRMISDGAAAKGDVMAAARIAGIAAAKRTGDLIP 78
Query 61 LCHPLPIYRAEVEYELHE-NFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHCE 119
LCHPL + V E + V+IL T T+G TGVEMEALTA S+A LT+YDM K
Sbjct 79 LCHPLGLDAVSVTITPCEPDRVKILATTTTLGRTGVEMEALTAVSVAALTIYDMCK--AV 136
Query 120 PEDLVLDQCKLLKKKGGKS 138
+ + Q L +K GG+S
Sbjct 137 DRAMEISQIVLQEKSGGRS 155
Score = 20.8 bits (42), Expect = 0.52
Identities = 9/28 (32%), Positives = 16/28 (57%), Gaps = 0/28 (0%)
Query 271 TLPGSRGGASESMAALLPAIVHIFDVCR 298
T G G E++ A+ A + I+D+C+
Sbjct 107 TTLGRTGVEMEALTAVSVAALTIYDMCK 134
Score = 20.4 bits (41), Expect = 0.69
Identities = 25/127 (20%), Positives = 49/127 (39%), Gaps = 16/127 (13%)
Query 133 KKGGKSHFKRTLRQAVSAAVIVLSDTVASGKKPDTAGKS----VVDTLNEAGFTPIHYQI 188
K G K + + +S D +A+ + A ++ + G + I
Sbjct 33 KASGLVIMKPSTLRMISDGAAAKGDVMAAARIAGIAAAKRTGDLIPLCHPLGLDAVSVTI 92
Query 189 LPDESDQLKDLVLELTQSYACIITVGGTGIGKRDITVDTLEPL----LERKLDGLMEAAR 244
P E D++K L A T+G TG+ +T ++ L + + +D ME ++
Sbjct 93 TPCEPDRVKIL--------ATTTTLGRTGVEMEALTAVSVAALTIYDMCKAVDRAMEISQ 144
Query 245 AFGQRRT 251
Q ++
Sbjct 145 IVLQEKS 151
>Q9NZB8 GTP 3',8-cyclase / Cyclic pyranopterin monophosphate synthase
[Homo sapiens]
Length=636
Score = 112 bits (281), Expect = 4e-31
Identities = 61/139 (44%), Positives = 90/139 (65%), Gaps = 4/139 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +VG KP++ R+A A A++ P +L++ +KGDAL ++AG+ AAK T +LIP
Sbjct 493 MVDVGRKPDTERVAVASAVVLLGPVAFKLVQQNQLKKGDALVVAQLAGVQAAKVTSQLIP 552
Query 61 LCHPLPIYRAEVEYELH--ENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCH + + +V+ EL + V+I + GPTGVEMEALT+A++A LTLYDM K
Sbjct 553 LCHHVALSHIQVQLELDSTRHAVKIQASCRARGPTGVEMEALTSAAVAALTLYDMCK--A 610
Query 119 EPEDLVLDQCKLLKKKGGK 137
D+VL++ KL+ K GG+
Sbjct 611 VSRDIVLEEIKLISKTGGQ 629
Score = 18.9 bits (37), Expect = 2.7
Identities = 11/36 (31%), Positives = 21/36 (58%), Gaps = 4/36 (11%)
Query 162 GKKPDTAGKSVVDTLNEAGFTPIHYQILPDESDQLK 197
G+KPDT +V + G P+ ++++ + +QLK
Sbjct 497 GRKPDTERVAVASAVVLLG--PVAFKLV--QQNQLK 528
Score = 18.1 bits (35), Expect = 4.7
Identities = 6/25 (24%), Positives = 14/25 (56%), Gaps = 0/25 (0%)
Query 274 GSRGGASESMAALLPAIVHIFDVCR 298
G G E++ + A + ++D+C+
Sbjct 585 GPTGVEMEALTSAAVAALTLYDMCK 609
>Q8IQF1 GTP 3',8-cyclase / Cyclic pyranopterin monophosphate synthase
[Drosophila melanogaster]
Length=565
Score = 109 bits (273), Expect = 4e-30
Identities = 63/144 (44%), Positives = 83/144 (58%), Gaps = 4/144 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +VG KP + R+A A+A + +L+ KGD L +IAGI+ AKRT ELIP
Sbjct 412 MVDVGAKPSTTRLARAEATVQVGEKLTQLIADNQVAKGDVLTVAQIAGIMGAKRTAELIP 471
Query 61 LCHPLPIYRAEVEYEL--HENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCH + + +V+ L E V + TV G TGVEMEALTA S+A LT+YDM K
Sbjct 472 LCHNISLSSVKVQATLLKTEQSVRLEATVRCSGQTGVEMEALTAVSVAALTVYDMCK--A 529
Query 119 EPEDLVLDQCKLLKKKGGKSHFKR 142
D+ + +LL K GGK F+R
Sbjct 530 VSHDICITNVRLLSKSGGKRDFQR 553
Score = 22.7 bits (47), Expect = 0.17
Identities = 8/29 (28%), Positives = 17/29 (59%), Gaps = 0/29 (0%)
Query 274 GSRGGASESMAALLPAIVHIFDVCRDLPH 302
G G E++ A+ A + ++D+C+ + H
Sbjct 504 GQTGVEMEALTAVSVAALTVYDMCKAVSH 532
>Q5RKZ7 GTP 3',8-cyclase / Cyclic pyranopterin monophosphate synthase
[Mus musculus]
Length=636
Score = 106 bits (265), Expect = 5e-29
Identities = 60/139 (43%), Positives = 87/139 (63%), Gaps = 4/139 (3%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +VG KPE+ R+A A A++ P +L++ +KGDAL ++AG+ AAK T +LIP
Sbjct 493 MVDVGGKPETERVAVASAMVLLGPVAFKLVQQNQLKKGDALVVAQLAGVQAAKLTSQLIP 552
Query 61 LCHPLPIYRAEVEYELH--ENFVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLKPHC 118
LCH + + +V EL + V I + GPTGVEMEALT+A++A LT+YDM K
Sbjct 553 LCHHVALSHVQVHLELDSTRHAVLIQASCRARGPTGVEMEALTSAAMAALTVYDMCK--A 610
Query 119 EPEDLVLDQCKLLKKKGGK 137
D+V+ + KL+ K GG+
Sbjct 611 VSRDIVVTEVKLISKTGGQ 629
Score = 18.5 bits (36), Expect = 3.6
Identities = 6/25 (24%), Positives = 14/25 (56%), Gaps = 0/25 (0%)
Query 274 GSRGGASESMAALLPAIVHIFDVCR 298
G G E++ + A + ++D+C+
Sbjct 585 GPTGVEMEALTSAAMAALTVYDMCK 609
Score = 17.7 bits (34), Expect = 6.2
Identities = 7/13 (54%), Positives = 8/13 (62%), Gaps = 0/13 (0%)
Query 115 KPHCEPEDLVLDQ 127
K HC P+ L L Q
Sbjct 425 KRHCIPKALPLSQ 437
>Q2FVX9 Cyclic pyranopterin monophosphate synthase [Staphylococcus
aureus (strain NCTC 8325 / PS 47)]
Length=164
Score = 96.3 bits (238), Expect = 1e-27
Identities = 61/152 (40%), Positives = 82/152 (54%), Gaps = 8/152 (5%)
Query 1 MKNVGMKPESYRIAEAQAILYAPPHCIELLRTGNTEKGDALKTGRIAGILAAKRTDELIP 60
M +V K + R A A + + + + KG+ L T +IAGI+AAK T LIP
Sbjct 15 MVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTLIP 74
Query 61 LCHPLPIYRAEVEYELHEN-----FVEILTTVETIGPTGVEMEALTAASIAGLTLYDMLK 115
+CHPLP+ +V + E + I TTV T G TGVEMEALTAAS LT+YDM K
Sbjct 75 MCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTK 134
Query 116 PHCEPEDLVLDQCKLLKKKGGKS-HFKRTLRQ 146
+ +++ + L K GGKS F+R Q
Sbjct 135 --AVDKGMIIGETYLESKSGGKSGDFQRQSNQ 164
Lambda K H a alpha
0.320 0.138 0.401 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1100924
Database: d019ba3116564757946aec18815a6bb4.SwissProt.fasta
Posted date: May 20, 2024 10:08 PM
Number of letters in database: 5,214
Number of sequences in database: 22
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
Loading
Data ...
