Comparative Genomics

ACIAD1987 / SwissProt Alignments

BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: bc98e16cf7c2920a632fd7271be02464.SwissProt.fasta
           21 sequences; 6,101 total letters



Query= ACIAD1987

Length=266
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

P0AE19 Methionine aminopeptidase [Escherichia coli O6:H1 (strain ...  297     3e-105
P0AE20 Methionine aminopeptidase [Escherichia coli O157:H7]           297     3e-105
P0AE21 Methionine aminopeptidase [Shigella flexneri]                  297     3e-105
P0AE18 Methionine aminopeptidase [Escherichia coli (strain K12)]      297     3e-105
P0A1X7 Methionine aminopeptidase [Salmonella typhi]                   294     7e-104
P0A1X6 Methionine aminopeptidase [Salmonella typhimurium (strain ...  294     7e-104
P44421 Methionine aminopeptidase [Haemophilus influenzae (strain ...  288     1e-101
Q9ZCD3 Methionine aminopeptidase [Rickettsia prowazekii (strain M...  287     2e-101
P57324 Methionine aminopeptidase [Buchnera aphidicola subsp. Acyr...  283     8e-100
Q8K9T1 Methionine aminopeptidase [Buchnera aphidicola subsp. Schi...  278     1e-97 
P53579 Methionine aminopeptidase A [Synechocystis sp. (strain PCC...  259     3e-90 
Q89AP3 Methionine aminopeptidase [Buchnera aphidicola subsp. Baiz...  257     3e-89 
P53580 Methionine aminopeptidase B [Synechocystis sp. (strain PCC...  247     2e-85 
P19994 Methionine aminopeptidase 1 [Bacillus subtilis (strain 168)]   227     9e-78 
P69000 Methionine aminopeptidase [Clostridium acetobutylicum (str...  224     8e-77 
P9WK19 Methionine aminopeptidase 2 [Mycobacterium tuberculosis (s...  225     2e-76 
P53582 Methionine aminopeptidase 1 [Homo sapiens]                     226     8e-76 
Q8BP48 Methionine aminopeptidase 1 [Mus musculus]                     222     4e-74 
Q9SLN5 Methionine aminopeptidase 1A [Arabidopsis thaliana]            214     5e-71 
Q9FV52 Methionine aminopeptidase 1B, chloroplastic [Arabidopsis t...  206     4e-68 
Q9FV50 Methionine aminopeptidase 1D, chloroplastic/mitochondrial ...  205     5e-68 


>P0AE19 Methionine aminopeptidase [Escherichia coli O6:H1 (strain 
CFT073 / ATCC 700928 / UPEC)]
Length=264

 Score = 297 bits (761),  Expect = 3e-105
 Identities = 136/247 (55%), Positives = 188/247 (76%), Gaps = 0/247 (0%)

Query  6    VTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGY  65
            ++IK  +DIE +RV+GRLAA+VLEMI PYVKPGVST  LD IC+++IV+    + A +GY
Sbjct  3    ISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGY  62

Query  66   HGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPEA  125
            HG+ K+ C S+NEVVCHGIP   K+L+DGDI+NIDV +IKDG+ GDTS+M++VG+     
Sbjct  63   HGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMG  122

Query  126  KKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQPN  185
            ++L + T E++   +++VKPG  L +IG AIQ   + EG+S+V+EYCGHGIG+ +HE+P 
Sbjct  123  ERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQ  182

Query  186  ILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVTE  245
            +LHY      +VL+ GM FTIEPMVNAGK +++ + DGWTV T D+SLSAQ+EH + VT+
Sbjct  183  VLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTD  242

Query  246  TGFELLT  252
             G E+LT
Sbjct  243  NGCEILT  249


>P0AE20 Methionine aminopeptidase [Escherichia coli O157:H7]
Length=264

 Score = 297 bits (761),  Expect = 3e-105
 Identities = 136/247 (55%), Positives = 188/247 (76%), Gaps = 0/247 (0%)

Query  6    VTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGY  65
            ++IK  +DIE +RV+GRLAA+VLEMI PYVKPGVST  LD IC+++IV+    + A +GY
Sbjct  3    ISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGY  62

Query  66   HGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPEA  125
            HG+ K+ C S+NEVVCHGIP   K+L+DGDI+NIDV +IKDG+ GDTS+M++VG+     
Sbjct  63   HGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMG  122

Query  126  KKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQPN  185
            ++L + T E++   +++VKPG  L +IG AIQ   + EG+S+V+EYCGHGIG+ +HE+P 
Sbjct  123  ERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQ  182

Query  186  ILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVTE  245
            +LHY      +VL+ GM FTIEPMVNAGK +++ + DGWTV T D+SLSAQ+EH + VT+
Sbjct  183  VLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTD  242

Query  246  TGFELLT  252
             G E+LT
Sbjct  243  NGCEILT  249


>P0AE21 Methionine aminopeptidase [Shigella flexneri]
Length=264

 Score = 297 bits (761),  Expect = 3e-105
 Identities = 136/247 (55%), Positives = 188/247 (76%), Gaps = 0/247 (0%)

Query  6    VTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGY  65
            ++IK  +DIE +RV+GRLAA+VLEMI PYVKPGVST  LD IC+++IV+    + A +GY
Sbjct  3    ISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGY  62

Query  66   HGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPEA  125
            HG+ K+ C S+NEVVCHGIP   K+L+DGDI+NIDV +IKDG+ GDTS+M++VG+     
Sbjct  63   HGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMG  122

Query  126  KKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQPN  185
            ++L + T E++   +++VKPG  L +IG AIQ   + EG+S+V+EYCGHGIG+ +HE+P 
Sbjct  123  ERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQ  182

Query  186  ILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVTE  245
            +LHY      +VL+ GM FTIEPMVNAGK +++ + DGWTV T D+SLSAQ+EH + VT+
Sbjct  183  VLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTD  242

Query  246  TGFELLT  252
             G E+LT
Sbjct  243  NGCEILT  249


>P0AE18 Methionine aminopeptidase [Escherichia coli (strain K12)]
Length=264

 Score = 297 bits (761),  Expect = 3e-105
 Identities = 136/247 (55%), Positives = 188/247 (76%), Gaps = 0/247 (0%)

Query  6    VTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGY  65
            ++IK  +DIE +RV+GRLAA+VLEMI PYVKPGVST  LD IC+++IV+    + A +GY
Sbjct  3    ISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGY  62

Query  66   HGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPEA  125
            HG+ K+ C S+NEVVCHGIP   K+L+DGDI+NIDV +IKDG+ GDTS+M++VG+     
Sbjct  63   HGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMG  122

Query  126  KKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQPN  185
            ++L + T E++   +++VKPG  L +IG AIQ   + EG+S+V+EYCGHGIG+ +HE+P 
Sbjct  123  ERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQ  182

Query  186  ILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVTE  245
            +LHY      +VL+ GM FTIEPMVNAGK +++ + DGWTV T D+SLSAQ+EH + VT+
Sbjct  183  VLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTD  242

Query  246  TGFELLT  252
             G E+LT
Sbjct  243  NGCEILT  249


>P0A1X7 Methionine aminopeptidase [Salmonella typhi]
Length=264

 Score = 294 bits (752),  Expect = 7e-104
 Identities = 137/247 (55%), Positives = 187/247 (76%), Gaps = 0/247 (0%)

Query  6    VTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGY  65
            ++IK  +DIE +RV+GRLAA+VLEMI PY+KPGV+T  LD IC+++IV+    I A +GY
Sbjct  3    ISIKTSEDIEKMRVAGRLAAEVLEMIEPYIKPGVTTGELDRICNDYIVNEQHAISACLGY  62

Query  66   HGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPEA  125
            HG+ K+ C S+NEVVCHGIP   K L+DGDI+NIDV +IKD + GDTS+M++VG+     
Sbjct  63   HGYPKSVCISINEVVCHGIPDDAKHLKDGDIVNIDVTVIKDEFHGDTSKMFIVGKPTILG  122

Query  126  KKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQPN  185
            ++L + T E++  GI++VKPG  L  IG AIQ  A+ EG+S+V+EYCGHGIG+ +HE+P 
Sbjct  123  ERLCRVTQESLYLGIKMVKPGIRLRTIGAAIQKYAEGEGFSVVREYCGHGIGRGFHEEPQ  182

Query  186  ILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVTE  245
            +LHY     G+VL+ GM FTIEPM+NAG  +++ + DGWTV T D+SLSAQ+EH + VTE
Sbjct  183  VLHYDADDGGVVLQPGMTFTIEPMLNAGDYRIRTMKDGWTVKTKDRSLSAQYEHTIVVTE  242

Query  246  TGFELLT  252
             G E+LT
Sbjct  243  NGCEILT  249


>P0A1X6 Methionine aminopeptidase [Salmonella typhimurium (strain 
LT2 / SGSC1412 / ATCC 700720)]
Length=264

 Score = 294 bits (752),  Expect = 7e-104
 Identities = 137/247 (55%), Positives = 187/247 (76%), Gaps = 0/247 (0%)

Query  6    VTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGY  65
            ++IK  +DIE +RV+GRLAA+VLEMI PY+KPGV+T  LD IC+++IV+    I A +GY
Sbjct  3    ISIKTSEDIEKMRVAGRLAAEVLEMIEPYIKPGVTTGELDRICNDYIVNEQHAISACLGY  62

Query  66   HGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPEA  125
            HG+ K+ C S+NEVVCHGIP   K L+DGDI+NIDV +IKD + GDTS+M++VG+     
Sbjct  63   HGYPKSVCISINEVVCHGIPDDAKHLKDGDIVNIDVTVIKDEFHGDTSKMFIVGKPTILG  122

Query  126  KKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQPN  185
            ++L + T E++  GI++VKPG  L  IG AIQ  A+ EG+S+V+EYCGHGIG+ +HE+P 
Sbjct  123  ERLCRVTQESLYLGIKMVKPGIRLRTIGAAIQKYAEGEGFSVVREYCGHGIGRGFHEEPQ  182

Query  186  ILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVTE  245
            +LHY     G+VL+ GM FTIEPM+NAG  +++ + DGWTV T D+SLSAQ+EH + VTE
Sbjct  183  VLHYDADDGGVVLQPGMTFTIEPMLNAGDYRIRTMKDGWTVKTKDRSLSAQYEHTIVVTE  242

Query  246  TGFELLT  252
             G E+LT
Sbjct  243  NGCEILT  249


>P44421 Methionine aminopeptidase [Haemophilus influenzae (strain 
ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=268

 Score = 288 bits (738),  Expect = 1e-101
 Identities = 137/248 (55%), Positives = 185/248 (75%), Gaps = 1/248 (0%)

Query  6    VTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGY  65
            + I+ E++I  LR + +LA+ VL MI PYVK GV+T  LD ICHE++V+  KVIPA + Y
Sbjct  3    IPIRTEKEIVKLREACKLASDVLVMIEPYVKAGVTTGELDRICHEYMVNEQKVIPACLNY  62

Query  66   HGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLV-GEVAPE  124
            HGF K TC S+NEVVCHGIPS +K+L++GDI+NIDV +IKDGYFGD S+MY+V GE    
Sbjct  63   HGFPKATCISINEVVCHGIPSDDKVLKNGDIVNIDVTVIKDGYFGDNSKMYIVGGETNIR  122

Query  125  AKKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQP  184
            +KKLV+   EA+  GI+ VKP   L +IG A+Q   + + +S+V+EYCGHG+G  +H +P
Sbjct  123  SKKLVEAAQEALYVGIRTVKPDIRLNEIGKAVQKYTESQTFSVVREYCGHGVGTEFHCEP  182

Query  185  NILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVT  244
             +LHY     G++L+ GMVFTIEPM+NAGK +V+ + DGWTV T D+S SAQ+EH + VT
Sbjct  183  QVLHYYADDGGVILKPGMVFTIEPMINAGKKEVRVMGDGWTVKTKDRSHSAQYEHQLIVT  242

Query  245  ETGFELLT  252
            ETG E++T
Sbjct  243  ETGCEVMT  250


>Q9ZCD3 Methionine aminopeptidase [Rickettsia prowazekii (strain 
Madrid E)]
Length=259

 Score = 287 bits (735),  Expect = 2e-101
 Identities = 136/252 (54%), Positives = 191/252 (76%), Gaps = 3/252 (1%)

Query  5    TVTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVG  64
            T+ I  E+D   +R +G+LAA+ L+ I  +VKP V+T  L+D+CH FI      IPA + 
Sbjct  2    TIKIHTEKDFIKMRAAGKLAAETLDFITDHVKPNVTTNSLNDLCHNFITSH-NAIPAPLN  60

Query  65   YHGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPE  124
            Y GF K+ CTS+N VVCHGIP+ +K L++GDI+NIDV +I DG++GDTSRMY VG+VA +
Sbjct  61   YKGFPKSICTSINHVVCHGIPN-DKPLKNGDIVNIDVTVILDGWYGDTSRMYYVGDVAIK  119

Query  125  AKKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQP  184
             K+L++ TY+AM+ GI+VV+PGA LGDIG+AIQ+ A++  YS+V++Y GHGIG+V+H++P
Sbjct  120  PKRLIQVTYDAMMKGIEVVRPGAKLGDIGYAIQSYAEKHNYSVVRDYTGHGIGRVFHDKP  179

Query  185  NILHYGQPGHGMVLEKGMVFTIEPMVNAGK-SQVKELNDGWTVVTTDKSLSAQWEHMVAV  243
            +IL+YG+ G G+ L++GM FT+EPM+NAG    +    DGWTV T DKSLSAQ+EH + V
Sbjct  180  SILNYGRNGTGLTLKEGMFFTVEPMINAGNYDTILSKLDGWTVTTRDKSLSAQFEHTIGV  239

Query  244  TETGFELLTPWP  255
            T+ GFE+ T  P
Sbjct  240  TKDGFEIFTLSP  251


>P57324 Methionine aminopeptidase [Buchnera aphidicola subsp. 
Acyrthosiphon pisum (strain APS)]
Length=264

 Score = 283 bits (725),  Expect = 8e-100
 Identities = 128/245 (52%), Positives = 186/245 (76%), Gaps = 0/245 (0%)

Query  8    IKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGYHG  67
            IK E +I+ +R+SG+LAA+VLEMI  +++P +STE ++ ICH++IV   K I A +GYHG
Sbjct  5    IKTESEIKKMRISGKLAAEVLEMIKEHLQPKISTEDINQICHDYIVYKKKAISACLGYHG  64

Query  68   FTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPEAKK  127
            F K+ C S+N+VVCHGIPS N++ ++GDI+NID+AIIKDGY GDTS+M+ +G+ +  +K+
Sbjct  65   FPKSICISINDVVCHGIPSKNQVFKEGDIVNIDIAIIKDGYHGDTSKMFYIGKTSILSKR  124

Query  128  LVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQPNIL  187
            L +   E++   +++VKPG  L  IG  IQ   +   +S+VKEYCGHGIG+ +HE+P++L
Sbjct  125  LCQVARESLYLSLKLVKPGIPLYKIGEIIQNYVESNNFSVVKEYCGHGIGRNFHEEPHVL  184

Query  188  HYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVTETG  247
            HY    + ++L+KGM+FTIEPM+N+G  +VK + DGWTV T D+SLSAQ+EH V VTE G
Sbjct  185  HYKNKKNNIILKKGMIFTIEPMINSGNPEVKCMKDGWTVKTKDRSLSAQYEHTVLVTEYG  244

Query  248  FELLT  252
             ++LT
Sbjct  245  CDILT  249


>Q8K9T1 Methionine aminopeptidase [Buchnera aphidicola subsp. 
Schizaphis graminum (strain Sg)]
Length=261

 Score = 278 bits (711),  Expect = 1e-97
 Identities = 130/245 (53%), Positives = 179/245 (73%), Gaps = 2/245 (1%)

Query  8    IKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGYHG  67
            IK E +I+ ++VSG++AA+VLEMI  Y+KP +STE +++ICH FI+   K + A +GYHG
Sbjct  5    IKTESEIKKMKVSGKIAAEVLEMIENYIKPNISTEEINNICHNFIIKK-KAVSACLGYHG  63

Query  68   FTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPEAKK  127
            F K+ C SVN+VVCHGIP+ N+IL+ GDI+NIDV IIK  Y  DTS+M+LVG+    +++
Sbjct  64   FPKSICISVNDVVCHGIPNKNQILKSGDIVNIDVTIIKKNYHADTSKMFLVGQTNILSQR  123

Query  128  LVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQPNIL  187
            L K   E++   + ++KPG  L  IG  IQ   +   +S+VKEYCGHGIG+ +HE+P +L
Sbjct  124  LCKIAQESLYKSLNILKPGIPLYKIGEVIQNYVENNNFSVVKEYCGHGIGRAFHEEPYVL  183

Query  188  HYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVTETG  247
            HY    H ++LEKGM+FTIEPM+NAG  +VK + DGWTV T D SLSAQ+EH V +TE G
Sbjct  184  HYKNKSH-VILEKGMIFTIEPMINAGSHEVKCMKDGWTVKTKDHSLSAQYEHTVLITENG  242

Query  248  FELLT  252
             ++LT
Sbjct  243  CDILT  247


>P53579 Methionine aminopeptidase A [Synechocystis sp. (strain 
PCC 6803 / Kazusa)]
Length=253

 Score = 259 bits (661),  Expect = 3e-90
 Identities = 124/248 (50%), Positives = 174/248 (70%), Gaps = 1/248 (0%)

Query  5    TVTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVG  64
            T+T+ + ++IE +R +G+LAA +L+ + P V+PG++T  L+D   ++       I A +G
Sbjct  4    TITLLSRREIEKMRQAGQLAAALLDHLAPMVQPGITTLELNDEAEKW-TKAHGAISAPLG  62

Query  65   YHGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPE  124
            Y+GF K+ CTS+NEV+CHGIP   ++LQ GDI+N+DV  I DGY GD SR + VG  +P 
Sbjct  63   YNGFPKSICTSINEVICHGIPHRKRVLQAGDIINVDVTPIVDGYHGDCSRTFFVGTPSPV  122

Query  125  AKKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQP  184
            A+KLVK T E +  GI+ VKPG  +GDIG AIQ+ A+ +G+S+V+++ GHGI K++H  P
Sbjct  123  AEKLVKVTEECLRLGIEAVKPGGKIGDIGAAIQSHAEAQGFSVVRDFVGHGISKIFHTAP  182

Query  185  NILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVT  244
             I HYG+ G G  L  GMVFTIEPM+N G  +   L+DGWT +T D  LSAQ+EH +AVT
Sbjct  183  QIPHYGKAGKGKRLRPGMVFTIEPMINEGTWEAVLLDDGWTAITKDGKLSAQFEHTIAVT  242

Query  245  ETGFELLT  252
            E G E+LT
Sbjct  243  EDGVEILT  250


>Q89AP3 Methionine aminopeptidase [Buchnera aphidicola subsp. 
Baizongia pistaciae (strain Bp)]
Length=266

 Score = 257 bits (656),  Expect = 3e-89
 Identities = 119/248 (48%), Positives = 170/248 (69%), Gaps = 1/248 (0%)

Query  6    VTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGY  65
            + IKN  +I  +R+ G+L A VL+MI  Y+ PG++TE L++ICH +I       PA +GY
Sbjct  4    IFIKNINEINKMRLVGKLVADVLDMIKEYIVPGITTEELNNICHNYITYKQHAKPACLGY  63

Query  66   HGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPEA  125
             GF K+ CTS+N++VCHGIP+ N IL++GDI+NIDVAI+KD Y+ D S+M+ VG+     
Sbjct  64   QGFPKSICTSINDIVCHGIPNKNSILKNGDIINIDVAILKDKYYSDASKMFFVGKPTELG  123

Query  126  KKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQPN  185
            KKL     +++   +  ++PG  L  +G  IQ   +++ +SIVKEYCGHGIG+ +HE P 
Sbjct  124  KKLCYVAKKSLYLALYTIRPGINLQKLGKVIQNYVKKQNFSIVKEYCGHGIGRSFHEPPQ  183

Query  186  ILHYG-QPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVT  244
            ILH+     +  +L+ GM FT+EPM+N+G  +V+  NDGWTV T DKSLSAQ+EH + V 
Sbjct  184  ILHHNYYKSNTTILQSGMTFTVEPMINSGSCEVQCTNDGWTVKTKDKSLSAQYEHTILVN  243

Query  245  ETGFELLT  252
            E G E+LT
Sbjct  244  EEGCEILT  251


>P53580 Methionine aminopeptidase B [Synechocystis sp. (strain 
PCC 6803 / Kazusa)]
Length=274

 Score = 247 bits (631),  Expect = 2e-85
 Identities = 127/256 (50%), Positives = 174/256 (68%), Gaps = 8/256 (3%)

Query  3    ASTVTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVD------TL  56
            +S + + + ++++ +R  G+LAA +L  +   V+PGVST+ L+D    ++ D      TL
Sbjct  19   SSGLVLLSARELDKMRRVGQLAANLLNHLESMVQPGVSTQALNDEATRWMEDHGAISATL  78

Query  57   KVIPANVGYHGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMY  116
               P   GY  FT   CTS+NEVVCHGIP+P +IL+DGDI+NIDV +   GY GDTSR +
Sbjct  79   GYAPP--GYPPFTGAICTSINEVVCHGIPNPKQILKDGDIINIDVTLRLAGYHGDTSRTF  136

Query  117  LVGEVAPEAKKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGI  176
            LVG V+  A+KLV+ T E+M+ GI  +KPGA +GDIG AIQ  A+  G+S+V++  GHGI
Sbjct  137  LVGSVSATARKLVEATQESMMRGIAEIKPGARIGDIGAAIQAYAEASGFSVVRDMVGHGI  196

Query  177  GKVYHEQPNILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQ  236
            G+  H +  I HYG+ G G+ L  GMVFT+EPM+N G  ++  L DGWTV+T DK LSAQ
Sbjct  197  GRQMHTELQIPHYGKRGSGLKLRPGMVFTVEPMLNEGTYELTFLADGWTVITKDKKLSAQ  256

Query  237  WEHMVAVTETGFELLT  252
            +EH V VTE G E+LT
Sbjct  257  FEHTVVVTEEGVEILT  272


>P19994 Methionine aminopeptidase 1 [Bacillus subtilis (strain 
168)]
Length=248

 Score = 227 bits (578),  Expect = 9e-78
 Identities = 113/247 (46%), Positives = 160/247 (65%), Gaps = 2/247 (1%)

Query  6    VTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGY  65
            +  K  +++  +R +GR+ A   E +  ++KPG+ST+ LD I   FI      IP+  GY
Sbjct  2    IICKTPRELGIMREAGRIVALTHEELKKHIKPGISTKELDQIAERFIKKQ-GAIPSFKGY  60

Query  66   HGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPEA  125
            +GF  + C SVNE + HGIP  +++L+DGDI++ID+    +GY GD++  Y VG ++ + 
Sbjct  61   NGFRGSICVSVNEELVHGIPG-SRVLKDGDIISIDIGAKLNGYHGDSAWTYPVGNISDDD  119

Query  126  KKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQPN  185
            KKL++ T E++  G+Q  KPG  L +I HAIQT  + E +S+V+EY GHG+G+  HE P 
Sbjct  120  KKLLEVTEESLYKGLQEAKPGERLSNISHAIQTYVENEQFSVVREYVGHGVGQDLHEDPQ  179

Query  186  ILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVTE  245
            I HYG P  G  L+ GMV  IEPMVNAG   VK L D WTVVT D    A +EH +A+TE
Sbjct  180  IPHYGPPNKGPRLKPGMVLAIEPMVNAGSRYVKTLADNWTVVTVDGKKCAHFEHTIAITE  239

Query  246  TGFELLT  252
            TGF++LT
Sbjct  240  TGFDILT  246


>P69000 Methionine aminopeptidase [Clostridium acetobutylicum 
(strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)]
Length=250

 Score = 224 bits (572),  Expect = 8e-77
 Identities = 109/247 (44%), Positives = 159/247 (64%), Gaps = 1/247 (0%)

Query  6    VTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGY  65
            + IKN+ +IE++R +G++  + L M+    KPGV+T  LD +  +FI      IP+  GY
Sbjct  2    IIIKNDTEIEYMRQAGKIVGETLNMLEKAAKPGVTTADLDRLAEDFI-KKYNAIPSFKGY  60

Query  66   HGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPEA  125
             GF  + CTS+NE V HGIPS +++L +GDI+++D   I +GY GD +R + +GE++ EA
Sbjct  61   GGFPASICTSINEEVIHGIPSKHRVLHEGDIISVDCGAILNGYQGDAARTFAIGEISEEA  120

Query  126  KKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQPN  185
             KL+K T E+   G++    G  L DI H+IQ   +  GY +V++Y GHGIGK  HE P 
Sbjct  121  AKLIKVTKESFFKGVEKAVIGNRLTDISHSIQEYVESFGYGVVRDYVGHGIGKEMHEDPE  180

Query  186  ILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVTE  245
            + +YG+PG G  L  GMV  IEPMV+ G   VK  ++ WTVVT D SL+A +E+ VA+ +
Sbjct  181  VPNYGRPGRGPKLVHGMVLAIEPMVDVGTYMVKTQSNDWTVVTQDGSLAAHYENTVAILD  240

Query  246  TGFELLT  252
             G E+LT
Sbjct  241  NGPEILT  247


>P9WK19 Methionine aminopeptidase 2 [Mycobacterium tuberculosis 
(strain ATCC 25618 / H37Rv)]
Length=285

 Score = 225 bits (573),  Expect = 2e-76
 Identities = 113/245 (46%), Positives = 158/245 (64%), Gaps = 2/245 (1%)

Query  8    IKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGYHG  67
            ++  + IE +RV+GR+AA  L      V PGV+T+ LD I HE++VD     P+ +GY G
Sbjct  41   VQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDN-GAYPSTLGYKG  99

Query  68   FTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPEAKK  127
            F K+ CTS+NEV+CHGIP  + ++ DGDI+NIDV     G  GDT+  +  G+VA E + 
Sbjct  100  FPKSCCTSLNEVICHGIPD-STVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRL  158

Query  128  LVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQPNIL  187
            LV  T EA +  I  VKPG  L  IG  I++ A R GY++V+++ GHGIG  +H    +L
Sbjct  159  LVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVL  218

Query  188  HYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVTETG  247
            HY QP    +++ GM FTIEPM+N G    +  +DGWTVVT D+  +AQ+EH + VT+TG
Sbjct  219  HYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTG  278

Query  248  FELLT  252
             E+LT
Sbjct  279  VEILT  283


>P53582 Methionine aminopeptidase 1 [Homo sapiens]
Length=386

 Score = 226 bits (577),  Expect = 8e-76
 Identities = 112/249 (45%), Positives = 162/249 (65%), Gaps = 2/249 (1%)

Query  4    STVTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANV  63
            S + + + +DIE +R+  RLA +VL++    +KPGV+TE +D   H   +      P+ +
Sbjct  126  SQIKLLSSEDIEGMRLVCRLAREVLDVAAGMIKPGVTTEEIDHAVHLACI-ARNCYPSPL  184

Query  64   GYHGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAP  123
             Y+ F K+ CTSVNEV+CHGIP   + LQ+GDI+N+D+ + ++GY GD +  + VGEV  
Sbjct  185  NYYNFPKSCCTSVNEVICHGIPD-RRPLQEGDIVNVDITLYRNGYHGDLNETFFVGEVDD  243

Query  124  EAKKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQ  183
             A+KLV+TTYE ++  I  VKPG    ++G+ IQ  AQ  G+S+V+ YCGHGI K++H  
Sbjct  244  GARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTA  303

Query  184  PNILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAV  243
            PN+ HY +     V++ G VFTIEPM+  G  Q +   DGWT VT D   SAQ+EH + V
Sbjct  304  PNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLV  363

Query  244  TETGFELLT  252
            T+TG E+LT
Sbjct  364  TDTGCEILT  372


>Q8BP48 Methionine aminopeptidase 1 [Mus musculus]
Length=386

 Score = 222 bits (566),  Expect = 4e-74
 Identities = 110/249 (44%), Positives = 161/249 (65%), Gaps = 2/249 (1%)

Query  4    STVTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANV  63
            S + + + +DIE +R+  RLA +VL++    +K GV+TE +D   H   +      P+ +
Sbjct  126  SQIKLLSSEDIEGMRLVCRLAREVLDIAAGMIKAGVTTEEIDHAVHLACI-ARNCYPSPL  184

Query  64   GYHGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAP  123
             Y+ F K+ CTSVNEV+CHGIP   + LQ+GDI+N+D+ + ++GY GD +  + VG+V  
Sbjct  185  NYYNFPKSCCTSVNEVICHGIPD-RRPLQEGDIVNVDITLYRNGYHGDLNETFFVGDVDE  243

Query  124  EAKKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQ  183
             A+KLV+TTYE ++  I  VKPG    ++G+ IQ  AQ  G+S+V+ YCGHGI K++H  
Sbjct  244  GARKLVQTTYECLMQAIDAVKPGVRYRELGNIIQKHAQANGFSVVRSYCGHGIHKLFHTA  303

Query  184  PNILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAV  243
            PN+ HY +     V++ G VFTIEPM+  G  Q +   DGWT VT D   SAQ+EH + V
Sbjct  304  PNVPHYAKNKAVGVMKSGHVFTIEPMICEGGWQDETWPDGWTAVTRDGKRSAQFEHTLLV  363

Query  244  TETGFELLT  252
            T+TG E+LT
Sbjct  364  TDTGCEILT  372


>Q9SLN5 Methionine aminopeptidase 1A [Arabidopsis thaliana]
Length=398

 Score = 214 bits (546),  Expect = 5e-71
 Identities = 111/258 (43%), Positives = 156/258 (60%), Gaps = 3/258 (1%)

Query  6    VTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPANVGY  65
            V IK  + I+ +R + ++A +VL+     + PGV+T+ +D + HE  +      P+ + Y
Sbjct  139  VEIKTPEQIQRMRETCKIAREVLDAAARVIHPGVTTDEIDRVVHEATI-AAGGYPSPLNY  197

Query  66   HGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVAPEA  125
            + F K+ CTSVNEV+CHGIP   K L+DGDI+N+DV +   G  GD +  Y VG V   +
Sbjct  198  YFFPKSCCTSVNEVICHGIPDARK-LEDGDIVNVDVTVCYKGCHGDLNETYFVGNVDEAS  256

Query  126  KKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHEQPN  185
            ++LVK TYE +   I +VKPG    +IG  +   A   G S+V+ YCGHGIG ++H  PN
Sbjct  257  RQLVKCTYECLEKAIAIVKPGVRFREIGEIVNRHATMSGLSVVRSYCGHGIGDLFHCAPN  316

Query  186  ILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVAVTE  245
            I HY +     V++ G  FTIEPM+NAG  + +   DGWT VT D   SAQ+EH + VTE
Sbjct  317  IPHYARNKAVGVMKAGQTFTIEPMINAGGWRDRTWPDGWTAVTADGKRSAQFEHTLLVTE  376

Query  246  TGFELLTP-WPTGTGEYP  262
            TG E+LT   P+    YP
Sbjct  377  TGVEVLTARLPSSPDVYP  394


>Q9FV52 Methionine aminopeptidase 1B, chloroplastic [Arabidopsis 
thaliana]
Length=369

 Score = 206 bits (524),  Expect = 4e-68
 Identities = 107/250 (43%), Positives = 151/250 (60%), Gaps = 3/250 (1%)

Query  3    ASTVTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPAN  62
            +S   I   + I  +R +  LAA+VL      VKP V+T  +D   H+ I++     P+ 
Sbjct  121  SSEFQIPGPEGIAKMRAACELAARVLNYAGTLVKPSVTTNEIDKAVHDMIIEA-GAYPSP  179

Query  63   VGYHGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVA  122
            +GY GF K+ CTSVNE +CHGIP   + LQ GDI+NIDV +  DGY GDTSR +  GEV 
Sbjct  180  LGYGGFPKSVCTSVNECMCHGIPDSRQ-LQSGDIINIDVTVYLDGYHGDTSRTFFCGEVD  238

Query  123  PEAKKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHE  182
               K+LVK T E +  GI V K GA+   IG  I   A++ GY++V+ + GHG+G V+H 
Sbjct  239  EGFKRLVKVTEECLERGIAVCKDGASFKKIGKRISEHAEKFGYNVVERFVGHGVGPVFHS  298

Query  183  QPNILHYGQPGHGMVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMVA  242
            +P I HY     G+++E G  FTIEP++  G ++     D WT +T D  ++AQ+EH + 
Sbjct  299  EPLIYHYRNDEPGLMVE-GQTFTIEPILTIGTTECVTWPDNWTTLTADGGVAAQFEHTIL  357

Query  243  VTETGFELLT  252
            +T TG E+LT
Sbjct  358  ITRTGSEILT  367


>Q9FV50 Methionine aminopeptidase 1D, chloroplastic/mitochondrial 
[Arabidopsis thaliana]
Length=350

 Score = 205 bits (522),  Expect = 5e-68
 Identities = 108/251 (43%), Positives = 156/251 (62%), Gaps = 5/251 (2%)

Query  3    ASTVTIKNEQDIEHLRVSGRLAAQVLEMIIPYVKPGVSTEYLDDICHEFIVDTLKVIPAN  62
            +S + + +++ IE +R SG LAA+V +     VKPGV+T+ +D+  H  I++     P+ 
Sbjct  102  SSGLEVHDKKGIECMRASGILAARVRDYAGTLVKPGVTTDEIDEAVHNMIIEN-GAYPSP  160

Query  63   VGYHGFTKTTCTSVNEVVCHGIPSPNKILQDGDILNIDVAIIKDGYFGDTSRMYLVGEVA  122
            +GY GF K+ CTSVNE +CHGIP  ++ L+DGDI+NIDV +  +GY GDTS  +  G V 
Sbjct  161  LGYGGFPKSVCTSVNECICHGIPD-SRPLEDGDIINIDVTVYLNGYHGDTSATFFCGNVD  219

Query  123  PEAKKLVKTTYEAMLAGIQVVKPGATLGDIGHAIQTTAQREGYSIVKEYCGHGIGKVYHE  182
             +AKKLV+ T E++   I +  PG     IG  I   A +  Y +V+++ GHG+G V+H 
Sbjct  220  EKAKKLVEVTKESLDKAISICGPGVEYKKIGKVIHDLADKHKYGVVRQFVGHGVGSVFHA  279

Query  183  QPNILHYGQPGHG-MVLEKGMVFTIEPMVNAGKSQVKELNDGWTVVTTDKSLSAQWEHMV  241
             P +LH+     G MVL +   FTIEPM+  G       +D WTVVT D SLSAQ+EH +
Sbjct  280  DPVVLHFRNNEAGRMVLNQ--TFTIEPMLTIGSRNPIMWDDNWTVVTEDASLSAQFEHTI  337

Query  242  AVTETGFELLT  252
             +T+ G E+LT
Sbjct  338  LITKDGAEILT  348



Lambda      K        H        a         alpha
   0.319    0.137    0.415    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 1129700


  Database: bc98e16cf7c2920a632fd7271be02464.SwissProt.fasta
    Posted date:  May 13, 2024  3:11 AM
  Number of letters in database: 6,101
  Number of sequences in database:  21



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40