BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: 6e7d24083890b642e7b06ae2b562de45.SwissProt.fasta
           21 sequences; 5,717 total letters



Query= ACIAD1999

Length=240
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q6FAU1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [...  469     7e-174
A3M5X8 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [...  311     2e-111
B0V5E6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [...  309     1e-110
B0VQH8 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [...  309     1e-110
B2I2A2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [...  307     5e-110
Q7MHQ4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [...  184     1e-61 
Q8DC60 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [...  183     4e-61 
Q6LMT3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [...  181     2e-60 
Q3IDQ6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [...  175     7e-58 
B5FAF7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [...  172     7e-57 
Q88MF7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [...  171     2e-56 
Q46893 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [...  152     4e-49 
Q5N8G1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, ...  111     1e-32 
Q06755 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [...  102     7e-30 
P69834 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, ...  96.3    6e-27 
Q08113 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase /...  85.5    1e-22 
Q2G1C0 Ribitol-5-phosphate cytidylyltransferase 1 [Staphylococcus...  82.4    3e-22 
Q48230 Ribitol-5-phosphate cytidylyltransferase / Ribulose-5-phos...  81.3    5e-21 
Q8RKI9 Ribitol-5-phosphate cytidylyltransferase [Bacillus spizize...  76.6    4e-20 
Q48154 Ribitol-5-phosphate cytidylyltransferase / Ribulose-5-phos...  78.2    6e-20 
Q8DPI2 Ribitol-5-phosphate cytidylyltransferase [Streptococcus pn...  72.8    9e-19 


>Q6FAU1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
[Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)]
Length=239

 Score = 469 bits (1206),  Expect = 7e-174
 Identities = 239/239 (100%), Positives = 239/239 (100%), Gaps = 0/239 (0%)

Query  1    MKPHLHQISQIKLWAIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLTLEGYVL  60
            MKPHLHQISQIKLWAIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLTLEGYVL
Sbjct  1    MKPHLHQISQIKLWAIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLTLEGYVL  60

Query  61   AINEHDHVAQNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCV  120
            AINEHDHVAQNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCV
Sbjct  61   AINEHDHVAQNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCV  120

Query  121  SLSCLQALAEYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGV  180
            SLSCLQALAEYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGV
Sbjct  121  SLSCLQALAEYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGV  180

Query  181  LKHAIQLALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLILLSQKS  239
            LKHAIQLALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLILLSQKS
Sbjct  181  LKHAIQLALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLILLSQKS  239


>A3M5X8 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
[Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / 
LMG 1025 / NCDC KC755 / 5377)]
Length=238

 Score = 311 bits (796),  Expect = 2e-111
 Identities = 161/232 (69%), Positives = 181/232 (78%), Gaps = 0/232 (0%)

Query  6    HQISQIKLWAIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLTLEGYVLAINEH  65
            HQ SQIKLWA+IPAAGSGSRFSKT LKQYQ I++ TV+EHTV+RL+ L L GYVLAI + 
Sbjct  6    HQTSQIKLWAVIPAAGSGSRFSKTELKQYQYIQDATVIEHTVKRLSQLPLTGYVLAIGKQ  65

Query  66   DHVAQNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCL  125
            D  A  L    KHKAHFC GG+ERV SVLNAL YLS IA ++D+VLVHDAARPCV+  CL
Sbjct  66   DTFASTLSFQDKHKAHFCNGGVERVHSVLNALNYLSQIAEEDDWVLVHDAARPCVTFECL  125

Query  126  QALAEYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHAI  185
              L + AI+   +AILAIPVRDTLKQV     I KT+ R  LWQAQTPQIAKIG+LK AI
Sbjct  126  NTLVKNAIETNQSAILAIPVRDTLKQVNQEQQIDKTVSRELLWQAQTPQIAKIGILKKAI  185

Query  186  QLALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLILLSQ  237
            + AL+NN+ ITDEASALE  G  V VV GRSDNIKITY DDLELARLIL SQ
Sbjct  186  ETALKNNLTITDEASALESIGESVQVVMGRSDNIKITYPDDLELARLILQSQ  237


>B0V5E6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
[Acinetobacter baumannii (strain AYE)]
Length=238

 Score = 309 bits (791),  Expect = 1e-110
 Identities = 160/232 (69%), Positives = 180/232 (78%), Gaps = 0/232 (0%)

Query  6    HQISQIKLWAIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLTLEGYVLAINEH  65
            HQ SQ KLWA+IPAAGSGSRFSKT LKQYQ I++ TV+EHTV+RL+ L L GYVLAI + 
Sbjct  6    HQTSQTKLWAVIPAAGSGSRFSKTELKQYQYIQDATVIEHTVKRLSQLPLTGYVLAIGKQ  65

Query  66   DHVAQNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCL  125
            D  A  L    KHKAHFC GG+ERV SVLNAL YLS IA ++D+VLVHDAARPCV+  CL
Sbjct  66   DTFASTLSFQDKHKAHFCNGGVERVHSVLNALNYLSQIADEDDWVLVHDAARPCVTFECL  125

Query  126  QALAEYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHAI  185
              L + AI+   +AILAIPVRDTLKQV     I KT+ R  LWQAQTPQIAKIG+LK AI
Sbjct  126  NTLVKNAIETNQSAILAIPVRDTLKQVNQEQQIDKTVSRELLWQAQTPQIAKIGILKKAI  185

Query  186  QLALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLILLSQ  237
            + AL+NN+ ITDEASALE  G  V VV GRSDNIKITY DDLELARLIL SQ
Sbjct  186  ETALKNNLTITDEASALESIGESVQVVMGRSDNIKITYPDDLELARLILQSQ  237


>B0VQH8 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
[Acinetobacter baumannii (strain SDF)]
Length=238

 Score = 309 bits (791),  Expect = 1e-110
 Identities = 160/232 (69%), Positives = 180/232 (78%), Gaps = 0/232 (0%)

Query  6    HQISQIKLWAIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLTLEGYVLAINEH  65
            HQ SQ KLWA+IPAAGSGSRFSKT LKQYQ I++ TV+EHTV+RL+ L L GYVLAI + 
Sbjct  6    HQTSQTKLWAVIPAAGSGSRFSKTELKQYQYIQDATVIEHTVKRLSQLPLTGYVLAIGKQ  65

Query  66   DHVAQNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCL  125
            D  A  L    KHKAHFC GG+ERV SVLNAL YLS IA ++D+VLVHDAARPCV+  CL
Sbjct  66   DTFASTLSFQDKHKAHFCNGGVERVHSVLNALNYLSQIADEDDWVLVHDAARPCVTFECL  125

Query  126  QALAEYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHAI  185
              L + AI+   +AILAIPVRDTLKQV     I KT+ R  LWQAQTPQIAKIG+LK AI
Sbjct  126  NTLVKNAIETNQSAILAIPVRDTLKQVNQEQQIEKTVSRELLWQAQTPQIAKIGILKKAI  185

Query  186  QLALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLILLSQ  237
            + AL+NN+ ITDEASALE  G  V VV GRSDNIKITY DDLELARLIL SQ
Sbjct  186  ETALKNNLTITDEASALESIGESVQVVMGRSDNIKITYPDDLELARLILQSQ  237


>B2I2A2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
[Acinetobacter baumannii (strain ACICU)]
Length=238

 Score = 307 bits (787),  Expect = 5e-110
 Identities = 160/232 (69%), Positives = 180/232 (78%), Gaps = 0/232 (0%)

Query  6    HQISQIKLWAIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLTLEGYVLAINEH  65
            HQ SQ KLWA+IPAAGSGSRFSKT LKQYQ I++ TV+EHTV+RL+ L L GYVLAI + 
Sbjct  6    HQTSQTKLWAVIPAAGSGSRFSKTELKQYQYIQDATVIEHTVKRLSQLPLTGYVLAIGKQ  65

Query  66   DHVAQNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCL  125
            D  A  L    KHKAHFC GG+ERV SVLNAL YLS IA ++D+VLVHDAARPCV+  CL
Sbjct  66   DTFASTLSFQDKHKAHFCNGGVERVHSVLNALNYLSQIADEDDWVLVHDAARPCVTFECL  125

Query  126  QALAEYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHAI  185
              L + AI+   +AILAIPVRDTLKQV     I KT+ R  LWQAQTPQIAKIG+LK AI
Sbjct  126  NTLVKNAIETNQSAILAIPVRDTLKQVNQEQQIDKTVSRELLWQAQTPQIAKIGILKKAI  185

Query  186  QLALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLILLSQ  237
            + AL+NN+ ITDEASALE  G  V VV GRSDNIKITY DDLELARLIL SQ
Sbjct  186  ETALKNNLTITDEASALESIGESVLVVMGRSDNIKITYPDDLELARLILQSQ  237


>Q7MHQ4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
[Vibrio vulnificus (strain YJ016)]
Length=237

 Score = 184 bits (468),  Expect = 1e-61
 Identities = 108/231 (47%), Positives = 138/231 (60%), Gaps = 1/231 (0%)

Query  9    SQIKLWAIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERL-NGLTLEGYVLAINEHDH  67
            S   L A++PAAG GSR      KQY  I  KT+LEHT+ERL +   +   V+A++E D 
Sbjct  4    SMTSLVAVVPAAGVGSRMKADRPKQYLQIHGKTILEHTIERLLSHPAITQVVVAVSEDDP  63

Query  68   VAQNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCLQA  127
               +L + Q        GG ER DSVL+AL +LS      D+VLVHDAARPCV+   + A
Sbjct  64   YYSDLAIAQHPDIIRVAGGKERADSVLSALCFLSQQPQKTDWVLVHDAARPCVAHQDIDA  123

Query  128  LAEYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHAIQL  187
            L E    + T  ILA PVRDT+K+   +  I  T+DRN LW A TPQ+ K  VL  A+  
Sbjct  124  LIERCSSHETGGILATPVRDTMKRANAQQMIDHTVDRNALWHALTPQMFKAEVLTDALSD  183

Query  188  ALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLILLSQK  238
            AL   + ITDEASALE+ GA+  +VQG S NIK+T  +DL LA   L  +K
Sbjct  184  ALAQGVAITDEASALEWRGALPALVQGCSSNIKVTQPEDLALAEFYLSREK  234


>Q8DC60 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
[Vibrio vulnificus (strain CMCP6)]
Length=237

 Score = 183 bits (464),  Expect = 4e-61
 Identities = 107/231 (46%), Positives = 137/231 (59%), Gaps = 1/231 (0%)

Query  9    SQIKLWAIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERL-NGLTLEGYVLAINEHDH  67
            S   L A++PAAG GSR      KQY  I  KT+LEHT+ERL +   +   V+A++E D 
Sbjct  4    SMTSLVAVVPAAGVGSRMKADRPKQYLQIHGKTILEHTIERLLSHPAITQVVVAVSEDDP  63

Query  68   VAQNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCLQA  127
                L + Q        GG ER DSVL+AL++LS      D+VLVHDAARPCV+   + A
Sbjct  64   YYSELAIAQHPDIVRVAGGKERADSVLSALRFLSLQQQKADWVLVHDAARPCVAHQDIDA  123

Query  128  LAEYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHAIQL  187
            L E    + T  ILA PVRDT+K+   +  I  T+DRN LW A TPQ+ K  VL  A+  
Sbjct  124  LIERCSSHETGGILATPVRDTMKRANAQQMIDHTVDRNALWHALTPQMFKAEVLTDALSD  183

Query  188  ALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLILLSQK  238
            AL   + ITDEASALE+ G +  +VQG S NIK+T  +DL LA   L  +K
Sbjct  184  ALAQGVAITDEASALEWRGELPALVQGCSSNIKVTQPEDLALAEFYLSREK  234


>Q6LMT3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
[Photobacterium profundum (strain SS9)]
Length=234

 Score = 181 bits (459),  Expect = 2e-60
 Identities = 105/228 (46%), Positives = 143/228 (63%), Gaps = 8/228 (4%)

Query  12   KLWAIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERL-NGLTLEGYVLAINEHDHVAQ  70
            +L A++PAAG GSR +    KQY  I  KT+LEHT++RL +   +   ++AI++ D    
Sbjct  4    QLTAVVPAAGIGSRMAADRPKQYLHIAGKTILEHTIDRLFSHPAITRVIIAISQTDPYFA  63

Query  71   NLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCLQALAE  130
            +LPL    +     GG ER DSV   L   ++I  +  +VLVHDAARPCV L+ L+ L E
Sbjct  64   SLPLANDPRITVVDGGAERADSVFAGL---AAIDDENTWVLVHDAARPCVRLNDLERLVE  120

Query  131  YAIKYTTNAILAIPVRDTLK----QVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHAIQ  186
             AI+  + AILA PVRDT+K    Q+     I  T+DRN+LW A TPQ+ K+  LK ++Q
Sbjct  121  AAIRSDSGAILAAPVRDTMKRGCQQINGLQGIVSTVDRNNLWHALTPQMFKVKQLKDSLQ  180

Query  187  LALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLIL  234
             AL+    ITDEASALEY G +  +V+GRSDN+K+T  +DL LA   L
Sbjct  181  HALKEGAVITDEASALEYCGYIPQLVKGRSDNLKVTQPEDLALAGFYL  228


>Q3IDQ6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
[Pseudoalteromonas translucida (strain TAC 125)]
Length=241

 Score = 175 bits (443),  Expect = 7e-58
 Identities = 107/228 (47%), Positives = 142/228 (62%), Gaps = 10/228 (4%)

Query  15   AIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLT-LEGYVLAINEHDHVAQNLP  73
            AIIPAAG GSR    A KQY  +  KT+LEHT+ +L+ L  L   V+A+NE+D   + LP
Sbjct  17   AIIPAAGVGSRMQHNAPKQYIKLAGKTILEHTLTKLSALAQLNTIVVALNENDPYFEQLP  76

Query  74   LTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCLQALAEYAI  133
            +        C GG ER DSVLN+L +L+  A+  D+VLVHDAARP V++  +  L    I
Sbjct  77   VIDARIVRTC-GGKERADSVLNSLLFLA--ANPPDWVLVHDAARPLVTIDDINTLINECI  133

Query  134  KYTTNAILAIPVRDTLKQVVDRSHI--SKTIDRNHLWQAQTPQIAKIGVLKHAIQLALEN  191
                  ILA  V+DT+K    R HI   +T+ R+ LWQA TPQ  K   LK+A+Q AL +
Sbjct  134  SADEGGILASKVKDTIK----RGHIYAEQTVPRDDLWQALTPQFFKYEDLKNALQNALAS  189

Query  192  NIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLILLSQKS  239
               ITDEASA+E+A   V ++ GRSDNIKIT  +DL+LA  +L  Q++
Sbjct  190  GAVITDEASAIEWANKPVKLIPGRSDNIKITTPEDLDLAGFLLQKQQN  237


>B5FAF7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
[Aliivibrio fischeri (strain MJ11)]
Length=238

 Score = 172 bits (436),  Expect = 7e-57
 Identities = 102/229 (45%), Positives = 131/229 (57%), Gaps = 2/229 (1%)

Query  11   IKLWAIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLTLEG-YVLAINEHDHVA  69
            + + AI+PAAG GSR      KQY  +  KTVLEHT+E+L    L    V+AI + D   
Sbjct  7    LSITAIVPAAGVGSRMKADRPKQYLLLNGKTVLEHTIEQLLAFPLVNKVVVAITDGDPYF  66

Query  70   QNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCLQALA  129
              L L Q ++     GG ER DSVL+ L Y+      E +V+VHDAARPCV  S +  L 
Sbjct  67   PELTLAQDNRVIRVSGGKERADSVLSGLSYVQEHQLSE-WVMVHDAARPCVRHSDIDKLI  125

Query  130  EYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHAIQLAL  189
               I      ILA PVRDT+KQ      I  TIDR+ LW A TPQ+    +L  A+Q  L
Sbjct  126  TEVIPEHIGGILASPVRDTMKQATQEQCIETTIDRSVLWHALTPQLFTTELLYSALQTGL  185

Query  190  ENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLILLSQK  238
            + N+ ITDE+SA+E  G    +VQGR+DN+KIT  +DL+LA   L   K
Sbjct  186  DKNLSITDESSAIELMGYQPKLVQGRADNLKITQPEDLDLAEFYLQKMK  234


>Q88MF7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
[Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 
8728 / NCIMB 11950 / KT2440)]
Length=235

 Score = 171 bits (432),  Expect = 2e-56
 Identities = 95/220 (43%), Positives = 135/220 (61%), Gaps = 2/220 (1%)

Query  14   WAIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGL-TLEGYVLAINEHDHVAQNL  72
            WA+IPAAG G+R +    KQY  +  +T+LEH+++   G   L+G V++I E D     L
Sbjct  9    WAVIPAAGVGARMAADRPKQYLELAGQTLLEHSLDCFLGHPALKGVVVSIAEDDPYWPGL  68

Query  73   PLTQKHKAHFCKGGLERVDSVLNALQYLSSI-ASDEDYVLVHDAARPCVSLSCLQALAEY  131
                  + H   GG ER DSVLNAL  L +  A+D D+VLVHDAARP ++ S L  L   
Sbjct  69   RCASDPRIHCAAGGRERADSVLNALLVLHAQGAADSDWVLVHDAARPNLARSDLDKLLSE  128

Query  132  AIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHAIQLALEN  191
                    +LA+P RDTLK+      +S T+DR+ +WQA TPQ+ ++G L  A+   L +
Sbjct  129  LADDPVGGLLAVPARDTLKRADSHGRVSATVDRSTIWQAYTPQMFRLGALHRALAECLVS  188

Query  192  NIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELAR  231
            ++ +TDEASA+E++G    +V+GRSDNIK+T  +DLE  R
Sbjct  189  DVVVTDEASAIEWSGQAPRLVEGRSDNIKVTRPEDLEWLR  228


>Q46893 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
[Escherichia coli (strain K12)]
Length=236

 Score = 152 bits (384),  Expect = 4e-49
 Identities = 96/228 (42%), Positives = 127/228 (56%), Gaps = 6/228 (3%)

Query  9    SQIKLWAIIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLT-LEGYVLAINEHDH  67
            + + + A++PAAG G R      KQY +I N+T+LEH+V  L     ++  V+AI+  D 
Sbjct  4    THLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDS  63

Query  68   VAQNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCLQA  127
                LPL    +     GG ER DSVL  L+     A D  +VLVHDAARPC+    L  
Sbjct  64   RFAQLPLANHPQITVVDGGDERADSVLAGLK----AAGDAQWVLVHDAARPCLHQDDLAR  119

Query  128  LAEYAIKYTTNAILAIPVRDTLKQVVD-RSHISKTIDRNHLWQAQTPQIAKIGVLKHAIQ  186
            L   +    T  ILA PVRDT+K+    ++ I+ T+DRN LW A TPQ     +L   + 
Sbjct  120  LLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLT  179

Query  187  LALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLIL  234
             AL     ITDEASALEY G    +V+GR+DNIK+T  +DL LA   L
Sbjct  180  RALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYL  227


>Q5N8G1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 
chloroplastic [Oryza sativa subsp. japonica]
Length=297

 Score = 111 bits (277),  Expect = 1e-32
 Identities = 71/225 (32%), Positives = 117/225 (52%), Gaps = 14/225 (6%)

Query  16   IIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLTLEGYVLAINEHDHV------A  69
            ++ + G G R   +  KQY  +    +  H+++    L     V+ + + D+        
Sbjct  78   VLLSGGQGKRMGASMPKQYLPLLGLPIALHSLKTFCQLKEVKEVVVVCDPDYKDIFEGSI  137

Query  70   QNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCLQALA  129
            +N+ +  K    F   G ER DSV N LQ    I  D + V VHD+ARP VS   ++ + 
Sbjct  138  ENVQIPIK----FALPGKERQDSVYNGLQ---EIDGDSELVCVHDSARPLVSSEDVKKVL  190

Query  130  EYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHAIQLAL  189
            E AI +   A+L +PV+ T+K+    S + KT+DR  LW+ QTPQ+ +  +L+   +L  
Sbjct  191  EDAIVHGA-AVLGVPVKATIKEADSNSFVVKTLDRKTLWEMQTPQVMRPSLLRDGFELVK  249

Query  190  ENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLIL  234
             + +++TD+ S +EY    V + +G   NIK+T  DDL LA  ++
Sbjct  250  RDGLEVTDDVSIVEYLKHSVYITEGSYTNIKVTTPDDLLLAERLM  294


>Q06755 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
[Bacillus subtilis (strain 168)]
Length=232

 Score = 102 bits (254),  Expect = 7e-30
 Identities = 81/227 (36%), Positives = 114/227 (50%), Gaps = 11/227 (5%)

Query  16   IIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNG-LTLEGYVLAINEHD--HVAQNL  72
            +IPAAG G R      K +  ++   V+ HT+   +     +  +L INE +  H  Q L
Sbjct  6    VIPAAGQGKRMKAGRNKLFIELKGDPVIIHTLRVFDSHRQCDKIILVINEQEREHFQQLL  65

Query  73   P-LTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCLQALAEY  131
                 +       GG ER  SV   L+ +      E  VLVHD ARP +    +  L   
Sbjct  66   SDYPFQTSIELVAGGDERQHSVYKGLKAVKQ----EKIVLVHDGARPFIKHEQIDELIAE  121

Query  132  AIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHAIQLALEN  191
            A + T  AILA+PV+DT+K+V D   +S+TI+R+ LW  QTPQ  ++ +L  A   A   
Sbjct  122  A-EQTGAAILAVPVKDTIKRVQDLQ-VSETIERSSLWAVQTPQAFRLSLLMKAHAEAERK  179

Query  192  NIKITDEASALE-YAGAVVDVVQGRSDNIKITYQDDLELARLILLSQ  237
                TD+AS +E   G  V VV+G   NIK+T  DDL  A  I+ S+
Sbjct  180  GFLGTDDASLVEQMEGGSVRVVEGSYTNIKLTTPDDLTSAEAIMESE  226


>P69834 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 
chloroplastic [Arabidopsis thaliana]
Length=302

 Score = 96.3 bits (238),  Expect = 6e-27
 Identities = 58/153 (38%), Positives = 85/153 (56%), Gaps = 4/153 (3%)

Query  82   FCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCLQALAEYAIKYTTNAIL  141
            F   G ER DSV + LQ    I  + + V +HD+ARP V+   ++ + +        A+L
Sbjct  150  FAIPGKERQDSVYSGLQ---EIDVNSELVCIHDSARPLVNTEDVEKVLKDGSAVGA-AVL  205

Query  142  AIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHAIQLALENNIKITDEASA  201
             +P + T+K+V   S + KT+DR  LW+ QTPQ+ K  +LK   +L     +++TD+ S 
Sbjct  206  GVPAKATIKEVNSDSLVVKTLDRKTLWEMQTPQVIKPELLKKGFELVKSEGLEVTDDVSI  265

Query  202  LEYAGAVVDVVQGRSDNIKITYQDDLELARLIL  234
            +EY    V V QG   NIK+T  DDL LA  IL
Sbjct  266  VEYLKHPVYVSQGSYTNIKVTTPDDLLLAERIL  298


>Q08113 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 
/ 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Rhodobacter 
capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)]
Length=379

 Score = 85.5 bits (210),  Expect = 1e-22
 Identities = 74/223 (33%), Positives = 105/223 (47%), Gaps = 11/223 (5%)

Query  16   IIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLTLEGYVLAINEHDHVAQNLPLT  75
            II AAG G+R  +   KQ++ +  + VL  TV    GL   G +L +   D +   + L 
Sbjct  6    IIVAAGRGTRAGEGLPKQWRDLAGRPVLAQTVAAFAGL---GRILVVLHPDDMGLGMDLL  62

Query  76   QKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCLQALAEYAIKY  135
                     GG  R +SV NAL+ L    SD   VL+HD ARP V  S   A+   A++ 
Sbjct  63   GGSVV-LVAGGSTRSESVKNALEALEG--SDVTRVLIHDGARPLVPASVTAAVLA-ALET  118

Query  136  TTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHAIQLALENNIKI  195
            T  A  A+ V D L +  +   ++ T DR  L++AQTPQ  +   +  A +         
Sbjct  119  TPGAAPALAVTDALWRG-EAGLVAGTQDREGLYRAQTPQGFRFPEILAAHRAHPGG---A  174

Query  196  TDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLILLSQK  238
             D+     +AG  V +V G  DN+KITY  D   A  IL  +K
Sbjct  175  ADDVEVARHAGLSVAIVPGHEDNLKITYAPDFARAEAILRERK  217


>Q2G1C0 Ribitol-5-phosphate cytidylyltransferase 1 [Staphylococcus 
aureus (strain NCTC 8325 / PS 47)]
Length=238

 Score = 82.4 bits (202),  Expect = 3e-22
 Identities = 63/230 (27%), Positives = 110/230 (48%), Gaps = 10/230 (4%)

Query  14   WAIIPAAGSGSRFSKTAL-KQYQTIENKTVLEHTVERLNGLTLEGYVLAINEHDHVAQNL  72
            +A I A G GSR     L KQ+  ++NK +L HT+E+   +     ++       +    
Sbjct  3    YAGILAGGIGSRMGNVPLPKQFLDLDNKPILIHTLEKFILINDFEKIIIATPQQWMTHTK  62

Query  73   PLTQKHKA-----HFCKGGLERVDSVLNALQYLSSI--ASDEDYVLVHDAARPCVSLSCL  125
               +K K         +GG +R D+++N ++++ S    +D+D ++ HDA RP ++   +
Sbjct  63   DTLRKFKISDERIEVIQGGSDRNDTIMNIVKHIESTNGINDDDVIVTHDAVRPFLTHRII  122

Query  126  QALAEYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHA-  184
            +   + A++Y       I   DT+    D   I     RN ++Q QTPQ   I +LK + 
Sbjct  123  KENIQAALEYGA-VDTVIDAIDTIVTSKDNQTIDAIPVRNEMYQGQTPQSFNINLLKESY  181

Query  185  IQLALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLIL  234
             QL+ E    ++D    +      V +V+G   NIK+T   DL++A  I+
Sbjct  182  AQLSDEQKSILSDACKIIVETNKPVRLVKGELYNIKVTTPYDLKVANAII  231


>Q48230 Ribitol-5-phosphate cytidylyltransferase / Ribulose-5-phosphate 
reductase [Haemophilus influenzae]
Length=474

 Score = 81.3 bits (199),  Expect = 5e-21
 Identities = 71/232 (31%), Positives = 107/232 (46%), Gaps = 15/232 (6%)

Query  16   IIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLTLEGYVLAINEH------DHVA  69
            II A G GSR      KQ+  I  KT LEHT+           ++ ++E       + + 
Sbjct  9    IILAGGVGSRMGLGYPKQFSKIAGKTALEHTLAIFQEHKEIDEIIIVSERTSYRRIEDIV  68

Query  70   QNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIASDEDYVLVHDAARPCVSLSCLQALA  129
              L  ++ ++  F  GG ER DS L+A+  L     +   +++HDA RP ++   +    
Sbjct  69   SKLDFSKVNRIIF--GGKERSDSTLSAITALQD-EPENTKLIIHDAVRPLLATEIISECI  125

Query  130  EYAIKYTTNAI-LAIPVRDTLKQVV-DRSHISKTIDRNHLWQAQTPQIAKIGVLKHAIQL  187
                KY  NA+ +AIP  DT+  V  D   I K   R   +Q QTPQ  K+G LK A  +
Sbjct  126  AKLDKY--NAVDVAIPAVDTIVHVNNDTQEIIKIPKRAEYYQGQTPQAFKLGTLKKAYDI  183

Query  188  ALENNIKITDEASAL--EYAGAVVDVVQGRSDNIKITYQDDLELARLILLSQ  237
              +  I+ T + S +        V +V G   NIK+T   DL +A  +  S+
Sbjct  184  YTQGGIEGTCDCSIVLKTLPEERVGIVSGSETNIKLTRPVDLFIADKLFQSR  235


>Q8RKI9 Ribitol-5-phosphate cytidylyltransferase [Bacillus spizizenii 
(strain ATCC 23059 / NRRL B-14472 / W23)]
Length=237

 Score = 76.6 bits (187),  Expect = 4e-20
 Identities = 59/231 (26%), Positives = 109/231 (47%), Gaps = 10/231 (4%)

Query  13   LWAIIPAAGSGSRFSKTAL-KQYQTIENKTVLEHTVERLNGLTLEGYVLAINEHDHVAQN  71
            ++A I A G GSR     + KQ+  +  + ++ HTVE+         +L ++  + +   
Sbjct  2    IYAEILAGGKGSRMGNVNMPKQFLPLNKRPIIIHTVEKFLLNDRFDKILIVSPKEWINHT  61

Query  72   LPLTQKH-----KAHFCKGGLERVDSVLNALQYLSSI--ASDEDYVLVHDAARPCVSLSC  124
              + +K      +    +GG +R +S+++ ++Y+       D D ++ HD+ RP ++   
Sbjct  62   KDILKKFIGQDDRLVVVEGGSDRNESIMSGIRYIEKEFGIQDNDVIITHDSVRPFLTHRI  121

Query  125  LQALAEYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLKHA  184
            +    +  ++Y       I   DT+    D+  IS    R++++Q QTPQ  +I  L   
Sbjct  122  IDENIDAVLQYGA-VDTVISAIDTIIASEDQEFISDIPVRDNMYQGQTPQSFRISKLVEL  180

Query  185  I-QLALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLIL  234
              +L+ E    +TD       AG  V +V+G   NIK+T   DL++A  IL
Sbjct  181  YNKLSDEQKAVLTDACKICSLAGEKVKLVRGEVFNIKVTTPYDLKVANAIL  231


>Q48154 Ribitol-5-phosphate cytidylyltransferase / Ribulose-5-phosphate 
reductase [Haemophilus influenzae]
Length=474

 Score = 78.2 bits (191),  Expect = 6e-20
 Identities = 74/242 (31%), Positives = 107/242 (44%), Gaps = 35/242 (14%)

Query  16   IIPAAGSGSRFSKTALKQYQTIENKTVLEHTVERLNGLTLEGYVLAINEHDHVAQNLPLT  75
            II A G GSR      KQ+  I  KT LEHT            +    EH  + + + ++
Sbjct  9    IILAGGIGSRMGLGYPKQFSKIAGKTALEHT------------IFIFQEHKEIDEIIIVS  56

Query  76   QK----------HKAHFCK------GGLERVDSVLNALQYLSSIASDEDYVLVHDAARPC  119
            ++           KA F K      GG ER DS L+A+  L     +   +++HDA RP 
Sbjct  57   ERTSYRRIEDIVSKAGFSKVNRIIFGGKERSDSTLSAITALQDEPRNTK-LIIHDAVRPL  115

Query  120  VSLSCLQALAEYAIKYTTNAI-LAIPVRDTLKQV-VDRSHISKTIDRNHLWQAQTPQIAK  177
            ++   +        KY  NA+ +AIP  DT+  V  D   I K   R   +Q QTPQ  K
Sbjct  116  LATEIISECIAKLDKY--NAVDVAIPAVDTIVHVNNDTQEIIKIPKRAEYYQGQTPQAFK  173

Query  178  IGVLKHAIQLALENNIKITDEASAL--EYAGAVVDVVQGRSDNIKITYQDDLELARLILL  235
            +G LK A  +  +  I+ T + S +        V +V G   NIK+T   DL +A  +  
Sbjct  174  LGTLKKAYDIYTQGGIEGTCDCSIVLKTLPEERVGIVSGFETNIKLTRPVDLFIADKLFQ  233

Query  236  SQ  237
            S+
Sbjct  234  SR  235


>Q8DPI2 Ribitol-5-phosphate cytidylyltransferase [Streptococcus 
pneumoniae (strain ATCC BAA-255 / R6)]
Length=235

 Score = 72.8 bits (177),  Expect = 9e-19
 Identities = 63/233 (27%), Positives = 115/233 (49%), Gaps = 13/233 (6%)

Query  13   LWAIIPAAGSGSRFSKTAL-KQYQTIENKTVLEHTVER-LNGLTLEGYVLAIN------E  64
            ++A I A G+G+R   + L KQ+  + ++ +L HT+E+ +   ++E  V+ ++       
Sbjct  2    IYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEPSIEKIVVGVHGDWVSHA  61

Query  65   HDHVAQNLPLTQKHKAHFCKGGLERVDSVLNALQYLSSIA--SDEDYVLVHDAARPCVSL  122
             D V + LPL  K +    KGG +R  S+ N ++ + +    + ED V+ HD+ RP ++L
Sbjct  62   EDLVDKYLPL-YKERIIITKGGADRNTSIKNIIEAIDAYRPLTPEDIVVTHDSVRPFITL  120

Query  123  SCLQALAEYAIKYTTNAILAIPVRDTLKQVVDRSHISKTIDRNHLWQAQTPQIAKIGVLK  182
              +Q   + A  +     +   V DT+ +  +   I+   +R HL+Q QTPQ  +     
Sbjct  121  RMIQDNIQLAQNHDAVDTVVEAV-DTIVESTNGQFITDIPNRAHLYQGQTPQTFRCKDFM  179

Query  183  HAI-QLALENNIKITDEASALEYAGAVVDVVQGRSDNIKITYQDDLELARLIL  234
                 L+ E    +TD        G  V + +G   N+KIT   DL++A+ ++
Sbjct  180  DLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLKITTVTDLKIAKSMI  232



Lambda      K        H        a         alpha
   0.320    0.133    0.378    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 930540


  Database: 6e7d24083890b642e7b06ae2b562de45.SwissProt.fasta
    Posted date:  May 13, 2024  5:38 PM
  Number of letters in database: 5,717
  Number of sequences in database:  21



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40