BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: bbb416f58999a7c202f867159a64b3f9.SwissProt.fasta
12 sequences; 2,201 total letters
Query= ACIAD2118
Length=209
Score E
Sequences producing significant alignments: (Bits) Value
Q9KBI9 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Halal... 75.9 9e-21
A6VX14 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Marin... 56.6 5e-14
Q9KPK1 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Vibri... 56.2 7e-14
Q7MNR7 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Vibri... 52.8 1e-12
Q8DEP0 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Vibri... 52.8 1e-12
A5W059 4-hydroxy-4-methyl-2-oxoglutarate aldolase/4-carboxy-4-hyd... 46.6 4e-10
C1D7M1 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Larib... 45.4 5e-10
Q0SY60 Regulator of ribonuclease activity A [Shigella flexneri se... 43.1 3e-09
Q87SD2 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Vibri... 42.4 6e-09
Q88JX9 4-carboxy-4-hydroxy-2-oxoadipic acid aldolase [Pseudomonas... 42.7 8e-09
Q5Z3P5 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Nocar... 40.8 2e-08
G2IQQ8 4-carboxy-4-hydroxy-2-oxoadipate aldolase [Sphingobium sp.... 40.0 7e-08
>Q9KBI9 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Halalkalibacterium
halodurans (strain ATCC BAA-125 / DSM 18197
/ FERM 7344 / JCM 9153 / C-125)]
Length=210
Score = 75.9 bits (185), Expect = 9e-21
Identities = 55/182 (30%), Positives = 93/182 (51%), Gaps = 4/182 (2%)
Query 9 LCDYTDIATSTIGHVIDD--GHLPQIHAMNRVHHVVGKVRTVVLHSINATNLRQALIEST 66
+ + I T+ I +D I +N VVG RTV + S + + +A+ E++
Sbjct 9 ITQFRTIPTTCISDALDGLTNLTSTIKPLNENDQVVGPARTVQVASGDNLAVLKAMYEAS 68
Query 67 PGEVLVIDARKLKHRACWGEQRHRAAIFHQLAAVVVLGAITDITAIRNMKVPVFAQSVSC 126
PG+V+VIDA+ RA G+ A +A VV GAI DI A + + P+F + +
Sbjct 69 PGDVIVIDAKGDCTRAIAGDFVLGMAKTLGIAGFVVDGAIRDIRASKALNFPIFCRGTTI 128
Query 127 LTTRKEGESIVDFDQTIQFEHSCIDSGDIMIGDADGVFILKEDQAKQLLPKFQALQQDEQ 186
++K G I + + I I GD+++GDADGV ++ + Q + +L K + Q D++
Sbjct 129 AASKKTG--IGNINVPISCGGVPIRPGDLIVGDADGVTVIPKGQEENVLQKAKKKQADDE 186
Query 187 QK 188
+
Sbjct 187 AR 188
>A6VX14 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Marinomonas
sp. (strain MWYL1)]
Length=161
Score = 56.6 bits (135), Expect = 5e-14
Identities = 39/132 (30%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Query 40 HVVGKVRTVVLHSINATNLRQALIESTPGEVLVIDARKLKHRACWGEQRHRAAIFHQLAA 99
H G+V TV N+ +R+ + E+ G+V+VID K RA G+ A+ +
Sbjct 31 HFYGEVVTVSCFEDNS-RVRELVAENGKGKVMVIDGGGSKRRALLGDMLAEKAVDNGWEG 89
Query 100 VVVLGAITDITAIRNMKVPVFAQSVSCLTTRKEGESIVDFDQTIQFEHSCIDSGDIMIGD 159
V+ GAI DI A + + + A + T K G + D +T++F I GD + D
Sbjct 90 FVINGAIRDIAAQSQLNIGIHALCAHPMPTEKRG--LGDLGKTLRFAGMTIAQGDYIYCD 147
Query 160 ADGVFILKEDQA 171
+G+ + K+ A
Sbjct 148 LNGIVVSKQPLA 159
>Q9KPK1 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Vibrio
cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba
N16961)]
Length=161
Score = 56.2 bits (134), Expect = 7e-14
Identities = 34/123 (28%), Positives = 63/123 (51%), Gaps = 3/123 (2%)
Query 43 GKVRTVVLHSINATNLRQALIESTPGEVLVIDARKLKHRACWGEQRHRAAIFHQLAAVVV 102
G++ TV + N+ +R L ++ G+VLV+D H+A G+Q AI + V++
Sbjct 34 GEIVTVRCYHDNS-KVRDVLSQNGKGKVLVVDGHGSCHKALMGDQLAILAIKNDWEGVII 92
Query 103 LGAITDITAIRNMKVPVFAQSVSCLTTRKEGESIVDFDQTIQFEHSCIDSGDIMIGDADG 162
GA+ D+ A+ M + + A S T K G V+ T+ ++ ++ GD + D +G
Sbjct 93 YGAVRDVVAMSEMDLGIKALGTSPFKTEKRGAGQVNV--TLTMQNQIVEPGDYLYADWNG 150
Query 163 VFI 165
+ +
Sbjct 151 ILM 153
>Q7MNR7 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Vibrio
vulnificus (strain YJ016)]
Length=160
Score = 52.8 bits (125), Expect = 1e-12
Identities = 36/126 (29%), Positives = 61/126 (48%), Gaps = 3/126 (2%)
Query 43 GKVRTVVLHSINATNLRQALIESTPGEVLVIDARKLKHRACWGEQRHRAAIFHQLAAVVV 102
G++ TV + N+ +R L E+ G+VLV+D +A G+Q AI + V+V
Sbjct 34 GEIVTVRCYHDNS-KVRDVLSENGKGKVLVVDGHGSCQKALLGDQLAILAIENDWEGVIV 92
Query 103 LGAITDITAIRNMKVPVFAQSVSCLTTRKEGESIVDFDQTIQFEHSCIDSGDIMIGDADG 162
GA+ D+ + M++ + A S T K G V+ T+ + + D + D +G
Sbjct 93 FGAVRDVAQMSQMELGIKALGTSPFKTEKRGAGEVNV--TLTMHNQMVQPKDYIYADWNG 150
Query 163 VFILKE 168
+ I KE
Sbjct 151 ILISKE 156
>Q8DEP0 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Vibrio
vulnificus (strain CMCP6)]
Length=160
Score = 52.8 bits (125), Expect = 1e-12
Identities = 36/126 (29%), Positives = 61/126 (48%), Gaps = 3/126 (2%)
Query 43 GKVRTVVLHSINATNLRQALIESTPGEVLVIDARKLKHRACWGEQRHRAAIFHQLAAVVV 102
G++ TV + N+ +R L E+ G+VLV+D +A G+Q AI + V+V
Sbjct 34 GEIVTVRCYHDNS-KVRDVLSENGKGKVLVVDGHGSCQKALLGDQLAILAIENDWEGVIV 92
Query 103 LGAITDITAIRNMKVPVFAQSVSCLTTRKEGESIVDFDQTIQFEHSCIDSGDIMIGDADG 162
GA+ D+ + M++ + A S T K G V+ T+ + + D + D +G
Sbjct 93 FGAVRDVAQMSQMELGIKALGTSPFKTEKRGAGEVNV--TLTMHNQMVQPKDYIYADWNG 150
Query 163 VFILKE 168
+ I KE
Sbjct 151 ILISKE 156
>A5W059 4-hydroxy-4-methyl-2-oxoglutarate aldolase/4-carboxy-4-hydroxy-2-oxoadipate
aldolase [Pseudomonas putida (strain ATCC
700007 / DSM 6899 / BCRC 17059 / F1)]
Length=238
Score = 46.6 bits (109), Expect = 4e-10
Identities = 38/168 (23%), Positives = 75/168 (45%), Gaps = 2/168 (1%)
Query 41 VVGKVRTVVLHSINATNLRQALIESTPGEVLVIDARKLKHRACWGEQRHRAAIFHQLAAV 100
+ G TV++ + A+ + PG+VLV+ +G+ + + A+
Sbjct 57 LAGSAVTVLVAPGDNWMFHVAVEQCRPGDVLVVSPSSPCTDGYFGDLLATSLQARGVRAL 116
Query 101 VVLGAITDITAIRNMKVPVFAQSVSCLTTRKEGESIVDFDQTIQFEHSCIDSGDIMIGDA 160
+V + D +R+M V+A++++ T KE V+ + I+ GDI++ D
Sbjct 117 IVDAGVRDTQTLRDMGFAVWARAINAQGTVKETLGSVNLP--VICGGQLINPGDIVVADD 174
Query 161 DGVFILKEDQAKQLLPKFQALQQDEQQKHSQFFSQNLIDDYYHFPERI 208
DGV +++ D+ + L E++K + + L D Y ER+
Sbjct 175 DGVVVVRRDECESTLVAAAERAGLEEEKRLRLAAGELGLDIYKMRERL 222
>C1D7M1 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Laribacter
hongkongensis (strain HLHK9)]
Length=159
Score = 45.4 bits (106), Expect = 5e-10
Identities = 34/121 (28%), Positives = 59/121 (49%), Gaps = 3/121 (2%)
Query 43 GKVRTVVLHSINATNLRQALIESTPGEVLVIDARKLKHRACWGEQRHRAAIFHQLAAVVV 102
G++ T+ + N+ +R+ L E G VLV+D + A G+Q A+ + A +VV
Sbjct 34 GRIATLKVFEDNS-RVREMLSEPGEGRVLVVDGGGSRRCALVGDQLGALAVRNGWAGIVV 92
Query 103 LGAITDITAIRNMKVPVFAQSVSCLTTRKEGESIVDFDQTIQFEHSCIDSGDIMIGDADG 162
G I D A+ + + V A + L + K G + + + + F+ + GD + D DG
Sbjct 93 YGCIRDSVALGLLPLGVRALATHPLKSVKNG--VGERELAVTFDGATFRPGDWLYADEDG 150
Query 163 V 163
V
Sbjct 151 V 151
>Q0SY60 Regulator of ribonuclease activity A [Shigella flexneri
serotype 5b (strain 8401)]
Length=161
Score = 43.1 bits (100), Expect = 3e-09
Identities = 34/127 (27%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
Query 43 GKVRTVVLHSINATNLRQALIESTPGEVLVIDARKLKHRACWGEQRHRAAIFHQLAAVVV 102
G++ TV N L L ++ G VLV+D RA + R A+ ++ +V+
Sbjct 34 GQIITVKCFEDNGL-LYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVI 92
Query 103 LGAITDITAIRNMKVPVFAQSVSCLTTRKEGESIVDFDQTIQFEHSCIDSGDIMIGDADG 162
GA+ + + + + + Q+++ + GESI + D + F SGD + D G
Sbjct 93 YGAVRQVDDLEELDIGI--QAMAAIPVGAAGESIGESDVRVNFGGVTFFSGDHLYADNTG 150
Query 163 VFILKED 169
+ IL ED
Sbjct 151 I-ILSED 156
>Q87SD2 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Vibrio
parahaemolyticus serotype O3:K6 (strain RIMD 2210633)]
Length=160
Score = 42.4 bits (98), Expect = 6e-09
Identities = 31/126 (25%), Positives = 58/126 (46%), Gaps = 3/126 (2%)
Query 43 GKVRTVVLHSINATNLRQALIESTPGEVLVIDARKLKHRACWGEQRHRAAIFHQLAAVVV 102
G++ TV + N+ +R+ L + G+VL++D +A G+Q I + ++V
Sbjct 34 GEIVTVRCYHDNS-KVREVLEQDGTGKVLIVDGHGSCQKALLGDQLAILGIENGWEGIIV 92
Query 103 LGAITDITAIRNMKVPVFAQSVSCLTTRKEGESIVDFDQTIQFEHSCIDSGDIMIGDADG 162
GA+ D+ + M + V A T K G + + + T+ + + + D +G
Sbjct 93 YGAVRDVAQMSQMDIGVQALGTCPFKTEKRG--VGEVNVTLTMLNQIVQPKHHVYADWNG 150
Query 163 VFILKE 168
V I KE
Sbjct 151 VLISKE 156
>Q88JX9 4-carboxy-4-hydroxy-2-oxoadipic acid aldolase [Pseudomonas
putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB
11950 / KT2440)]
Length=238
Score = 42.7 bits (99), Expect = 8e-09
Identities = 35/168 (21%), Positives = 75/168 (45%), Gaps = 2/168 (1%)
Query 41 VVGKVRTVVLHSINATNLRQALIESTPGEVLVIDARKLKHRACWGEQRHRAAIFHQLAAV 100
V G TV++ + A+ + PG+VLV+ +G+ + + +
Sbjct 57 VAGSAVTVLVAPGDNWMFHVAVEQCRPGDVLVVAPSSPCSDGYFGDLLATSLQARGVLGL 116
Query 101 VVLGAITDITAIRNMKVPVFAQSVSCLTTRKEGESIVDFDQTIQFEHSCIDSGDIMIGDA 160
V+ + D +R+M V++++++ T KE V+ + +++GDI++ D
Sbjct 117 VIDAGVRDSQTLRDMGFAVWSRAINAQGTVKEVLGSVNLP--LLCAGQLVNAGDIVVADD 174
Query 161 DGVFILKEDQAKQLLPKFQALQQDEQQKHSQFFSQNLIDDYYHFPERI 208
DGV +++ +A+ +L E++K + + L D Y R+
Sbjct 175 DGVVVVRHGEAQAVLEAATQRADLEERKRLRLAAGELGLDIYEMRPRL 222
>Q5Z3P5 Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase [Nocardia
farcinica (strain IFM 10152)]
Length=165
Score = 40.8 bits (94), Expect = 2e-08
Identities = 30/126 (24%), Positives = 57/126 (45%), Gaps = 3/126 (2%)
Query 43 GKVRTVVLHSINATNLRQALIESTPGEVLVIDARKLKHRACWGEQRHRAAIFHQLAAVVV 102
G++ T+ N ++Q L E G+VLV+D H A G+ + + A V+V
Sbjct 43 GRITTIRCFQDNLL-VKQTLGEPGEGKVLVVDGGASVHTALVGDIIAGRGVDNGWAGVIV 101
Query 103 LGAITDITAIRNMKVPVFAQSVSCLTTRKEGESIVDFDQTIQFEHSCIDSGDIMIGDADG 162
GA+ D +R + + + A + + + G + D ++F G+++ D DG
Sbjct 102 NGAVRDSAILRTLDIGIKALGTNPRKSTQTGSG--ERDVPVEFGGVTFVPGEMLYSDHDG 159
Query 163 VFILKE 168
+ + E
Sbjct 160 IVVRAE 165
>G2IQQ8 4-carboxy-4-hydroxy-2-oxoadipate aldolase [Sphingobium
sp. (strain NBRC 103272 / SYK-6)]
Length=228
Score = 40.0 bits (92), Expect = 7e-08
Identities = 28/148 (19%), Positives = 69/148 (47%), Gaps = 2/148 (1%)
Query 61 ALIESTPGEVLVIDARKLKHRACWGEQRHRAAIFHQLAAVVVLGAITDITAIRNMKVPVF 120
A+ + G++L++ +G+ +A +V+ + D+ + M PV+
Sbjct 75 AIEQLKAGDILLLAPTSPCEDGYFGDLLATSAQARGCRGLVIDAGVRDVRDLTEMNFPVW 134
Query 121 AQSVSCLTTRKEGESIVDFDQTIQFEHSCIDSGDIMIGDADGVFILKEDQAKQLLPKFQA 180
++++ T K ++ + + ++ ++ GD+++ D DGV ++ A+++L +A
Sbjct 135 SKAIYAQGTVKN--TLGSVNVPVVCANALVNPGDVIVADDDGVCVVPLANAEKVLEAARA 192
Query 181 LQQDEQQKHSQFFSQNLIDDYYHFPERI 208
+ +E K + + L D Y ER+
Sbjct 193 REANEGDKREKMANGVLGLDLYKMRERL 220
Lambda K H a alpha
0.326 0.138 0.411 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 302204
Database: bbb416f58999a7c202f867159a64b3f9.SwissProt.fasta
Posted date: May 11, 2024 7:14 AM
Number of letters in database: 2,201
Number of sequences in database: 12
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
