BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 95010f4dc84bdb1b85ac2b8192d7f2e9.SwissProt.fasta
19 sequences; 9,654 total letters
Query= ACIAD2122
Length=485
Score E
Sequences producing significant alignments: (Bits) Value
P94422 Uncharacterized MFS-type transporter YcnB [Bacillus subtil... 172 4e-51
P54585 Uncharacterized MFS-type transporter YhcA [Bacillus subtil... 159 4e-46
P9WG89 Multidrug resistance protein B homolog [Mycobacterium tube... 156 5e-45
O35018 Lincomycin resistance protein LmrB [Bacillus subtilis (str... 155 5e-45
Q180E3 Riboflavin transporter RibZ [Clostridioides difficile (str... 153 2e-44
P9WG88 Multidrug resistance protein B homolog [Mycobacterium tube... 153 8e-44
P96712 Multidrug resistance protein 3 [Bacillus subtilis (strain ... 150 5e-43
Q8Y9K8 Lincomycin resistance protein LmrB [Listeria monocytogenes... 145 2e-41
Q92EE1 Lincomycin resistance protein LmrB [Listeria innocua serov... 144 3e-41
P9WG87 Uncharacterized MFS-type transporter Rv1250 [Mycobacterium... 146 4e-41
P9WG86 Uncharacterized MFS-type transporter MT1289 [Mycobacterium... 146 4e-41
Q9RQ29 Fatty acid resistance protein FarB [Neisseria gonorrhoeae] 139 3e-39
P52600 Probable multidrug resistance protein EmrY [Escherichia co... 130 6e-36
P0AEJ0 Multidrug export protein EmrB [Escherichia coli (strain K12)] 127 6e-35
P42670 Puromycin resistance protein pur8 [Streptomyces alboniger] 125 4e-34
Q00538 Methylenomycin A resistance protein [Bacillus subtilis (st... 124 7e-34
P39886 Tetracenomycin C resistance and export protein [Streptomyc... 124 1e-33
P36554 Putative multidrug resistance protein MdtD [Escherichia co... 121 7e-33
P0A0J9 Antiseptic resistance protein [Staphylococcus aureus] 113 4e-30
>P94422 Uncharacterized MFS-type transporter YcnB [Bacillus subtilis
(strain 168)]
Length=472
Score = 172 bits (435), Expect = 4e-51
Identities = 116/464 (25%), Positives = 222/464 (48%), Gaps = 11/464 (2%)
Query 16 EKSMISRWVMLCVMLGTGTVS-LNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLS 74
E+ +R V++ ++L V+ LN + AL +M DFN+ W SF+L +
Sbjct 6 EQKPFNRSVIVGILLAGAFVAILNQTLLITALPHIMRDFNVDANQAQWLTTSFMLTNGIL 65
Query 75 LLLTGFLSQRFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLG 134
+ +T FL ++F R + + A+++F + +G A ++ +L R +Q +G+M+PL
Sbjct 66 IPITAFLIEKFTSRALLITAMSIFTAGTVVGAFAPNFPVLLTARIIQAAGAGIMMPLMQT 125
Query 135 IIFSVTSQQKRGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLG 194
+ ++ +KRG A G+ G +I A GP L + + W +LF + +PF V+ L+L
Sbjct 126 VFLTIFPIEKRGQAMGMVGLVISFAPAIGPTLSGWAVEAFSWRSLFYIILPFAVIDLILA 185
Query 195 WIHLPKQTKNRSERFDWFAYSLLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGL 254
I + T R + D + L + LL S V + S + +L+ +++ L
Sbjct 186 SILMKNVTTLRKTQIDILSVILSTFGFGGLLYGFSSVGSYG-WSSSTVLISLLVGVIALL 244
Query 255 WFWIITRKQQSSLIKWQIFNSQGFNYSLFISVMHTTGLFISLLVIPLFIQNTLKLSPIWT 314
F K + ++++++F F+ + + + L + ++PL+ QN ++ T
Sbjct 245 LFITRQMKLKKPMLEFRVFTFGVFSLTTLLGTLVFALLIGTETILPLYTQNVRDVTAFDT 304
Query 315 GILLMTSALTTSLCSKWAGEFLDQHGAKFLISFG---IILTALAFIGLALGGHLPLTYLI 371
G++L+ A+ S G D+ G + L G I LT+L F + L H L +++
Sbjct 305 GLMLLPGAVVMGFMSPIIGRIFDRVGGRGLAIAGFCIIFLTSLPF--MQLTDHTSLAWIV 362
Query 372 VCMALHGLGFGLSYMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAVAVVIAALYLQIR 431
V + LG + MP TTAG+N+L + L+ G A+NN +R+ ++ + + +
Sbjct 363 VLYTVRLLGTAMIMMPVTTAGINAL-PRHLIPHGTAMNNTIRQVGGSIGTALLVSVMSNQ 421
Query 432 THSLLASYDLDRAQLTSIRELFLICAALLLLALPYAWKFPYSKP 475
+ + ++ A L + F++ A + L+ + F KP
Sbjct 422 A-AHAGTTNVKHAALHGMNAAFIVAAVIALVG--FLLSFTLKKP 462
>P54585 Uncharacterized MFS-type transporter YhcA [Bacillus subtilis
(strain 168)]
Length=532
Score = 159 bits (402), Expect = 4e-46
Identities = 93/406 (23%), Positives = 196/406 (48%), Gaps = 4/406 (1%)
Query 24 VMLCVMLGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGFLSQ 83
+++ +M G LN + N A+ LM +F + + W ++L + + L+ FL
Sbjct 15 LLIVLMAGLFLAILNQTLLNVAMPHLMTEFGVSATTIQWLTTGYMLVNGVLIPLSAFLIT 74
Query 84 RFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGIIFSVTSQQ 143
RFG+R ++L A+ F L + + G A ++ T+L R +Q G++ PL + I + +
Sbjct 75 RFGQRSLFLVAMFCFTLGTLVCGIAPNFSTMLIGRLIQAVGGGILQPLVMTTILLIFPPE 134
Query 144 KRGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWIHLPKQTK 203
RG G++G +M A GP L ++ + W +F +P G + +++ + +
Sbjct 135 SRGKGMGIFGLAMMFAPAVGPTLSGWIIEHYTWRIMFYGLVPIGAIVIIVAFFIFKNMVE 194
Query 204 NRSERFDWFAYSLLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGLWFWIITRKQ 263
+ + D L SLL +S+ + + ++I ++ + F + +
Sbjct 195 PQKIKLDTLGAILSIVGFASLLYGVSEAGSDGWTDPI-VLSTVIIGAIAIVAFVVQQLRH 253
Query 264 QSSLIKWQIFNSQGFNYSLFISVMHTTGLFISLLVIPLFIQNTLKLSPIWTGILLMTSAL 323
++ +++F F+ S I+++ T L+ + ++P+++QN + + + +G+LL+ A+
Sbjct 254 DDPMLDFRVFKYDIFSLSSVINIIITVALYTGMFLLPIYLQNLVGFTALQSGLLLLPGAI 313
Query 324 TTSLCSKWAGEFLDQHGAKFLISFGIILTAL-AFIGLALGGHLPLTYLIVCMALHGLGFG 382
+ S +G D+ G + L G+++T + + L P T++++ ++ G
Sbjct 314 VMLIMSPISGILFDKFGPRPLAIIGLLVTVVTTYQYTQLTIDTPYTHIMLIYSIRAFGMS 373
Query 383 LSYMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAVAV-VIAALY 427
L MP TAG+N L L + G A++N LR+ ++ +I +Y
Sbjct 374 LLMMPVMTAGMNQL-PARLNSHGTAMSNTLRQISGSIGTSLITTIY 418
>P9WG89 Multidrug resistance protein B homolog [Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=540
Score = 156 bits (395), Expect = 5e-45
Identities = 101/386 (26%), Positives = 192/386 (50%), Gaps = 15/386 (4%)
Query 52 DFNIGEAAVSWFMVSFLLAMSLSLLLTGFLSQRFGKREVYLGALALFVLASAIGGCAKHY 111
DF +A V+W M ++LA++ + G+ + RFG R +++G++ F L S + A +
Sbjct 72 DFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNI 131
Query 112 ETVLAVRAVQGFASGLMIPLSLGIIFSVTSQQKRGAATGLWGAMIMLTLACGPMLGAVLL 171
++ R VQGF G++ P+S I+ ++ G + G ++L GP+LG L+
Sbjct 132 LLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLI 191
Query 172 IWWDWPALFLVNIPFGVLALVLGWIHLPKQTKNRSERFDWFAYSLLSASIISLLLALSQV 231
+ W +FLVN+P G+ ALVL I P+ SE FD+ LLS + + L +S
Sbjct 192 GAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSS 251
Query 232 K---TLSD---LESFKFFLLILISILSGLWFWIITRKQQSSLIKWQIFNSQGFNYSLFIS 285
T++D L L ++ + ++ W+ + + LI ++F ++ +
Sbjct 252 PARGTMADRHVLIPAITGLALIAAFVAHSWY-----RTEHPLIDMRLFQNRAVAQANMTM 306
Query 286 VMHTTGLFISLLVIPLFIQNTLKLSPIWTGILLMTSALTTSLCSKWAGEFLDQHGAKFLI 345
+ + GLF S L++P ++Q L SP+ +G+ ++ L L AG +D+ G ++
Sbjct 307 TVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIV 366
Query 346 SFGIILTALAFIGLALGGHLPLTYLIVC---MALHGLGFGLSYMPATTAGLNSLSDQELV 402
GI+L A A G YL + +A+ G+G G S MP + A + +L+ + +
Sbjct 367 LVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQ-I 425
Query 403 TQGAAINNLLRRTCSAVAVVIAALYL 428
+G+ + ++ ++ ++ + ++ L
Sbjct 426 ARGSTLISVNQQVGGSIGTALMSVLL 451
>O35018 Lincomycin resistance protein LmrB [Bacillus subtilis
(strain 168)]
Length=479
Score = 155 bits (392), Expect = 5e-45
Identities = 110/423 (26%), Positives = 198/423 (47%), Gaps = 15/423 (4%)
Query 24 VMLCVMLGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGFLSQ 83
+M+ ++L + ++ N AL LM + NI A V W +LL + + + ++G L Q
Sbjct 18 IMISLLLAGFIGMFSETALNIALTDLMKELNITAATVQWLTTGYLLVLGILVPVSGLLLQ 77
Query 84 RFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGIIFSVTSQQ 143
F R+++ +L +L + I A + +LA R VQ +GL++PL I +
Sbjct 78 WFTTRQLFTVSLIFSILGTFIAALAPSFSFLLAARIVQALGTGLLLPLMFNTILVIFPPH 137
Query 144 KRGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWIHLPKQTK 203
KRGAA G G +IM A GP ++L +W +F +++PF VLALV G ++ ++
Sbjct 138 KRGAAMGTIGLVIMFAPAIGPTFSGLVLEHLNWHWIFWISLPFLVLALVFGIAYMQNVSE 197
Query 204 NRSERFDWFAYSLLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGLWFWIITRKQ 263
+ D + L + ++ S S S ++ LI + GL + I
Sbjct 198 TTKPKIDVLSIILSTIGFGGIVFGFSNAGEGSGGWSSPTVIVSLIVGVVGLILFSI---- 253
Query 264 QSSLIKWQIFNSQGFNYSLFISVMHTTGLFI-------SLLVIPLFIQNTLKLSPIWTGI 316
+ +K + N + F Y +FI + +FI S+L++P+++Q L L+ +G+
Sbjct 254 RQLTMKQPMMNLRAFKYPMFI--LGVIMVFICMMVILSSMLLLPMYLQGGLVLTAFASGL 311
Query 317 LLMTSALTTSLCSKWAGEFLDQHGAKFLISFG-IILTALAFIGLALGGHLPLTYLIVCMA 375
+L+ + S G D++G K+L+ G +I+T + + + +I+
Sbjct 312 VLLPGGILNGFMSPVTGRLFDKYGPKWLVIPGFVIVTVVLWFFSNVTTTSTAVLIIILHT 371
Query 376 LHGLGFGLSYMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAVAVVIAALYLQIRTHSL 435
+G + MPA T GLN L +E G AI N L++ A+ +A + H
Sbjct 372 CLMIGISMIMMPAQTNGLNQL-PREFYPDGTAIMNTLQQMAGAIGTAVAVSIMAAGQHDY 430
Query 436 LAS 438
+++
Sbjct 431 MST 433
>Q180E3 Riboflavin transporter RibZ [Clostridioides difficile
(strain 630)]
Length=456
Score = 153 bits (386), Expect = 2e-44
Identities = 97/422 (23%), Positives = 202/422 (48%), Gaps = 16/422 (4%)
Query 19 MISRWVMLCVM-LGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLL 77
M +W++L ++ +G +L+ S N A + DF I + + W + +++L ++ ++L
Sbjct 1 MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQWVVTAYMLVVTATMLF 60
Query 78 TGFLSQRFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGIIF 137
G L + G +Y +F + S + + + T+++ R Q + +++ LGI+
Sbjct 61 FGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRIFQAVGASILMATGLGIVS 120
Query 138 SVTSQQKRGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWIH 197
+ ++G A G+ GA++ + GP++G ++L + WP++F++NIP G++A+ LG
Sbjct 121 NAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWPSIFIINIPIGIIAVFLGIKF 180
Query 198 LPKQT-KNRSERFDWFAYSLLSASIISLLLALSQ---VKTLSDLESFKFFLLILISILSG 253
LPK +++ FD L ++ +LLA+++ + + + FLL+ + +
Sbjct 181 LPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNTRLYLGITALIIFLLLALREV-- 238
Query 254 LWFWIITRKQQSSLIKWQIFNSQGFNYSLFISVMHTTGLFISLLVIPLFIQNTLKLSPIW 313
K + S I +F ++ F I V ++P +++ LSP+
Sbjct 239 --------KFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLLPFYLEQLKNLSPMM 290
Query 314 TGILLMTSALTTSLCSKWAGEFLDQHGAKFLISFGIILTALAFIGLA-LGGHLPLTYLIV 372
G ++ L L + AG D+HGAK +++ ++ +G+A L PL LIV
Sbjct 291 AGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLVGMALLKADSPLYLLIV 350
Query 373 CMALHGLGFGLSYMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAVAVVIAALYLQIRT 432
C+ + GLG G P ++ L + Q+ G+ + + + + ++ + Q T
Sbjct 351 CLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNLSFALGTAFFSSFFAQSLT 410
Query 433 HS 434
++
Sbjct 411 YN 412
>P9WG88 Multidrug resistance protein B homolog [Mycobacterium
tuberculosis (strain CDC 1551 / Oshkosh)]
Length=540
Score = 153 bits (386), Expect = 8e-44
Identities = 100/386 (26%), Positives = 191/386 (49%), Gaps = 15/386 (4%)
Query 52 DFNIGEAAVSWFMVSFLLAMSLSLLLTGFLSQRFGKREVYLGALALFVLASAIGGCAKHY 111
DF +A V+W M ++LA++ + G+ + RFG R +++G++ F L S + A +
Sbjct 72 DFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNI 131
Query 112 ETVLAVRAVQGFASGLMIPLSLGIIFSVTSQQKRGAATGLWGAMIMLTLACGPMLGAVLL 171
++ R VQGF G++ P+S I+ ++ G + G ++L GP+LG L+
Sbjct 132 LLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLI 191
Query 172 IWWDWPALFLVNIPFGVLALVLGWIHLPKQTKNRSERFDWFAYSLLSASIISLLLALSQV 231
+ W +FLVN+P G+ ALVL I P+ SE FD+ LLS + + L +S
Sbjct 192 GAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSS 251
Query 232 K---TLSD---LESFKFFLLILISILSGLWFWIITRKQQSSLIKWQIFNSQGFNYSLFIS 285
T++D L L ++ + ++ W+ + + LI ++F ++ +
Sbjct 252 PARGTMADRHVLIPAITGLALIAAFVAHSWY-----RTEHPLIDMRLFQNRAVAQANMTM 306
Query 286 VMHTTGLFISLLVIPLFIQNTLKLSPIWTGILLMTSALTTSLCSKWAGEFLDQHGAKFLI 345
+ + GLF S L++P ++Q L SP+ +G+ ++ L L AG +D+ G ++
Sbjct 307 TVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIV 366
Query 346 SFGIILTALAFIGLALGGHLPLTYLIVC---MALHGLGFGLSYMPATTAGLNSLSDQELV 402
GI+L A A G YL + +A+ G+G S MP + A + +L+ + +
Sbjct 367 LVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMVCSMMPLSGAAVQTLAPHQ-I 425
Query 403 TQGAAINNLLRRTCSAVAVVIAALYL 428
+G+ + ++ ++ ++ + ++ L
Sbjct 426 ARGSTLISVNQQVGGSIGTALMSVLL 451
>P96712 Multidrug resistance protein 3 [Bacillus subtilis (strain
168)]
Length=512
Score = 150 bits (379), Expect = 5e-43
Identities = 101/411 (25%), Positives = 200/411 (49%), Gaps = 9/411 (2%)
Query 17 KSMISRWVMLCVMLGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLL 76
K +++V+L ++LG +++N+ A+ ++ D + +W S+++A+ +
Sbjct 7 KQASTKFVVLGLLLGILMSAMDNTIVATAMGNIVADLGSFDK-FAWVTASYMVAVMAGMP 65
Query 77 LTGFLSQRFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGII 136
+ G LS +G++ +L L F++ SA+ G A+ ++ RA+QG G ++P++ II
Sbjct 66 IYGKLSDMYGRKRFFLFGLIFFLIGSALCGIAQTMNQLIIFRAIQGIGGGALLPIAFTII 125
Query 137 FSVTSQQKRGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWI 196
F + +KRG +G++GA+ L+ GP+LGA++ W +F +N+P G L+L
Sbjct 126 FDLFPPEKRGKMSGMFGAVFGLSSVLGPLLGAIITDSISWHWVFYINVPIGALSLFFIIR 185
Query 197 HLPKQTKNRSERFDWFAYSLLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGLWF 256
+ + ++R ++ DW L SI+ L+ AL D S + L ++ + + F
Sbjct 186 YYKESLEHRKQKIDWGGAITLVVSIVCLMFALELGGKTYDWNSIQIIGLFIVFAVFFIAF 245
Query 257 WIITRKQQSSLIKWQIFNSQGFNYSLFISVMHTTGLFISLLVIPLFIQNTLKLSPIWTGI 316
+I+ RK + +I + +F ++ F + ++ ++ I + IP+F+Q S G
Sbjct 246 FIVERKAEEPIISFWMFKNRLFATAQILAFLYGGTFIILAVFIPIFVQAVYGSSATSAGF 305
Query 317 LLMTSALTTSLCSKWAGEFLDQHGAKFLISFGIILTALAFIGLALGGHL----PLTYLIV 372
+L + + + S G F + + L+ +I FIG+ L ++ +L V
Sbjct 306 ILTPMMIGSVIGSMIGGIFQTKASFRNLMLISVI---AFFIGMLLLSNMTPDTARVWLTV 362
Query 373 CMALHGLGFGLSYMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAVAVVI 423
M + G G G ++ A +N L + T + N+ LR + V I
Sbjct 363 FMMISGFGVGFNFSLLPAASMNDLEPRFRGTANST-NSFLRSFGMTLGVTI 412
>Q8Y9K8 Lincomycin resistance protein LmrB [Listeria monocytogenes
serovar 1/2a (strain ATCC BAA-679 / EGD-e)]
Length=471
Score = 145 bits (365), Expect = 2e-41
Identities = 101/405 (25%), Positives = 193/405 (48%), Gaps = 10/405 (2%)
Query 25 MLCVMLGTGTVSL-NNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGFLSQ 83
++ L G + L + ++ N AL L+ F+I A V W +LL + + + ++G L Q
Sbjct 16 IIASFLMAGFIGLFSETALNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQ 75
Query 84 RFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGIIFSVTSQQ 143
F R ++ A++ + + I + + ++ R VQ + L++PL I + +
Sbjct 76 WFTTRGLFFTAVSFSIAGTLIAALSPTFAMLMIGRVVQAVGTALLLPLMFNTILLIFPEH 135
Query 144 KRGAATGLWGAMIMLTLACGPMLGAVLL--IWWDWPALFLVNIPFGVLALVLGWIHLPKQ 201
KRG+A G+ G +IM A GP + ++L + W+W +F +++PF ++AL+ G +
Sbjct 136 KRGSAMGMIGLVIMFAPAVGPTISGLILENLTWNW--IFWISLPFLIIALLFGMKFMQNV 193
Query 202 TKNRSERFDWFAYSLLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGLWFWIITR 261
+ + D + L + ++ A S + +I+ I GL+ W
Sbjct 194 SVVTKPKIDILSIILSTLGFGGVVFAFSSAGESGWGSATVLVSIIVGGIALGLFVW-RQL 252
Query 262 KQQSSLIKWQIFNSQGFNYSLFISVMHTTGLFISLLVIPLFIQNTLKLSPIWTGILLMTS 321
+ L+ ++F F L + + + +++++PL++QN+L L+ G++L+
Sbjct 253 TMEKPLMDLKVFKYPMFTLGLILVFISFMMILSTMILLPLYLQNSLALAAFSAGLVLLPG 312
Query 322 ALTTSLCSKWAGEFLDQHGAKFLI--SFGIILTALAFIGLALGGHLPLTYLIVCMALHGL 379
+ L S + G D +G + L+ F + + AL F+ G LT +IV ++ +
Sbjct 313 GVLNGLMSPFTGRLFDAYGPRALVIPGFIVAVVALFFLTRIEVGTSALT-IIVLHSVLMI 371
Query 380 GFGLSYMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAVAVVIA 424
G + MPA T GLN L +L G AI N L++ A+ +A
Sbjct 372 GISMVMMPAQTNGLNQL-PPKLYPDGTAIMNTLQQVSGAIGTAVA 415
>Q92EE1 Lincomycin resistance protein LmrB [Listeria innocua serovar
6a (strain ATCC BAA-680 / CLIP 11262)]
Length=471
Score = 144 bits (364), Expect = 3e-41
Identities = 102/405 (25%), Positives = 193/405 (48%), Gaps = 10/405 (2%)
Query 25 MLCVMLGTGTVSL-NNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGFLSQ 83
++ L G + L + ++ N AL L+ F+I A V W +LL + + + ++G L Q
Sbjct 16 IIASFLMAGFIGLFSETALNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQ 75
Query 84 RFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGIIFSVTSQQ 143
F R ++ A++ + + I + + ++ R VQ + L++PL I + +
Sbjct 76 WFTTRGLFFTAVSFSIAGTLIAALSPTFAMLMIGRVVQAVGTALLLPLMFNTILLIFPEH 135
Query 144 KRGAATGLWGAMIMLTLACGPMLGAVLL--IWWDWPALFLVNIPFGVLALVLGWIHLPKQ 201
KRG+A G+ G +IM A GP + ++L + W+W +F +++PF ++AL+ G +
Sbjct 136 KRGSAMGMIGLVIMFAPAVGPTISGLILENLTWNW--IFWISLPFLIIALLFGMKFMQNV 193
Query 202 TKNRSERFDWFAYSLLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGLWFWIITR 261
+ + D + L + ++ A S + +I+ I GL+ W
Sbjct 194 SVVTKPKIDILSIILSTLGFGGVVFAFSSAGENGWGSATVLVSIIVGGIALGLFVW-RQL 252
Query 262 KQQSSLIKWQIFNSQGFNYSLFISVMHTTGLFISLLVIPLFIQNTLKLSPIWTGILLMTS 321
+ L+ ++F F L + + + +++++PL++QN+L L+ G++L+
Sbjct 253 TMEKPLMDLKVFKYPMFTLGLILVFISFMMILSTMILLPLYLQNSLALAAFSAGLVLLPG 312
Query 322 ALTTSLCSKWAGEFLDQHGAKFLISFGIILT--ALAFIGLALGGHLPLTYLIVCMALHGL 379
+ L S + G D +G + L+ G I+ AL F+ G LT +IV ++ +
Sbjct 313 GVLNGLMSPFTGRLFDAYGPRALVIPGFIVAVIALFFLTRIEVGTSALT-IIVLHSVLMI 371
Query 380 GFGLSYMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAVAVVIA 424
G + MPA T GLN L +L G AI N L++ A+ +A
Sbjct 372 GISMVMMPAQTNGLNQL-PPKLYPDGTAIMNTLQQVSGAIGTAVA 415
>P9WG87 Uncharacterized MFS-type transporter Rv1250 [Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=579
Score = 146 bits (368), Expect = 4e-41
Identities = 106/412 (26%), Positives = 189/412 (46%), Gaps = 10/412 (2%)
Query 23 WVMLCVMLGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGFLS 82
W M M+G + L+++ A +M IG A V W ++LLA ++ +L+ G L
Sbjct 22 WAM---MVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLG 78
Query 83 QRFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGIIFSVTSQ 142
RFG + +YL L +F +AS G + ++A R VQG +GL+ P +L I +
Sbjct 79 DRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPA 138
Query 143 QKRGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWIHLPKQT 202
+RG A G WG + + GP+ G L+ W +F VN+P GV+ L+L +P
Sbjct 139 HRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIP-AL 197
Query 203 KNRSERFDWFAYSLLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGLWFWIITRK 262
+ RFDWF L A + ++ L Q ++ + ++ I +S +W R
Sbjct 198 PHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYW-QARN 256
Query 263 QQSSLIKWQIFNSQGFNYS-LFISVMHTTGLFISLLVIPLFIQNTLKLSPIWTGILLMTS 321
+ LI ++FN + F+ S L I+++ G + +L + + Q LSP T +L +
Sbjct 257 AREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGM-MLPVTFYAQAVCGLSPTHTAVLFAPT 315
Query 322 ALTTSLCSKWAGEFLDQHGAKFLISFGIILTALAFIGL--ALGGHLPLTYLIVCMALHGL 379
A+ + + + G +D+ ++ FG + A+A L + P+ L++ G+
Sbjct 316 AIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGV 375
Query 380 GFGLSYMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAVAVVIAALYLQIR 431
+ P T +L L + + N +R+ + + A ++ R
Sbjct 376 AGAFVWSPLTVTATRNLR-PHLAGASSGVFNAVRQLGAVLGSASMAAFMTSR 426
>P9WG86 Uncharacterized MFS-type transporter MT1289 [Mycobacterium
tuberculosis (strain CDC 1551 / Oshkosh)]
Length=579
Score = 146 bits (368), Expect = 4e-41
Identities = 106/412 (26%), Positives = 189/412 (46%), Gaps = 10/412 (2%)
Query 23 WVMLCVMLGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGFLS 82
W M M+G + L+++ A +M IG A V W ++LLA ++ +L+ G L
Sbjct 22 WAM---MVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLG 78
Query 83 QRFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGIIFSVTSQ 142
RFG + +YL L +F +AS G + ++A R VQG +GL+ P +L I +
Sbjct 79 DRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPA 138
Query 143 QKRGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWIHLPKQT 202
+RG A G WG + + GP+ G L+ W +F VN+P GV+ L+L +P
Sbjct 139 HRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIP-AL 197
Query 203 KNRSERFDWFAYSLLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGLWFWIITRK 262
+ RFDWF L A + ++ L Q ++ + ++ I +S +W R
Sbjct 198 PHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYW-QARN 256
Query 263 QQSSLIKWQIFNSQGFNYS-LFISVMHTTGLFISLLVIPLFIQNTLKLSPIWTGILLMTS 321
+ LI ++FN + F+ S L I+++ G + +L + + Q LSP T +L +
Sbjct 257 AREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGM-MLPVTFYAQAVCGLSPTHTAVLFAPT 315
Query 322 ALTTSLCSKWAGEFLDQHGAKFLISFGIILTALAFIGL--ALGGHLPLTYLIVCMALHGL 379
A+ + + + G +D+ ++ FG + A+A L + P+ L++ G+
Sbjct 316 AIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGV 375
Query 380 GFGLSYMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAVAVVIAALYLQIR 431
+ P T +L L + + N +R+ + + A ++ R
Sbjct 376 AGAFVWSPLTVTATRNLR-PHLAGASSGVFNAVRQLGAVLGSASMAAFMTSR 426
>Q9RQ29 Fatty acid resistance protein FarB [Neisseria gonorrhoeae]
Length=507
Score = 139 bits (351), Expect = 3e-39
Identities = 94/405 (23%), Positives = 188/405 (46%), Gaps = 3/405 (1%)
Query 23 WVMLCVMLGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGFLS 82
WV L + L L+ + N A+ + + +W + SF +A ++S+ LTGFL+
Sbjct 13 WVTLSLGLAVFMEVLDTTIANVAVPVIAGNLGAATTQGTWVITSFSVANAVSVPLTGFLA 72
Query 83 QRFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGIIFSVTSQ 142
+R G+ +++ A A FV+AS + G A + ++++ R +QGF +G +IPLS ++ +
Sbjct 73 KRIGEVKLFTAAAAGFVIASWLCGIAPNLQSLVVFRILQGFIAGPLIPLSQSLLMASYPP 132
Query 143 QKRGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWIHLP-KQ 201
KR A LW +++ GP+LG + W W +F +NIP G+++ + W HL ++
Sbjct 133 AKRMLALALWAMTVVVAPVLGPILGGWISGNWHWGWIFFINIPIGIISAWITWKHLKHRE 192
Query 202 TKNRSERFDWFAYSLLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGLWFWIITR 261
T D+ +L+ I +L + L + K L S + L + +++ +F +
Sbjct 193 TATVRTPTDYVGLTLMMVGIGALQMMLDRGKELDWFASGEIITLGITALVCLSYFIVWEL 252
Query 262 KQQSSLIKWQIFNSQGFNYSLFISVMHTTGLFISLLVIPLFIQNTLKLSPIWTGILLMTS 321
++ ++ +F + F + + +L ++PL +Q L + W G+
Sbjct 253 GEKYPIVDLSLFKDRNFTVGAIATSLGFMVYMGTLTLLPLVLQTNLGYTSAWAGLAAAPV 312
Query 322 ALTTSLCSKWAGEFLDQHGAKFLISFGIILTALAFIGLA-LGGHLPLTYLIVCMALHGLG 380
+ S G F ++ + L++ + A F + + +I G+G
Sbjct 313 GILPVFLSPLIGRFGNKIDMRLLVTASFLTFAFTFYWRTDFYADMDIGNVIWPQFWQGVG 372
Query 381 FGLSYMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAVAVVIAA 425
+ ++P TT L+ + ++ G +++N LR V V + +
Sbjct 373 VAMFFLPLTTITLSHMKGGQIAAAG-SLSNFLRVLMGGVGVSVVS 416
>P52600 Probable multidrug resistance protein EmrY [Escherichia
coli (strain K12)]
Length=512
Score = 130 bits (327), Expect = 6e-36
Identities = 89/401 (22%), Positives = 191/401 (48%), Gaps = 8/401 (2%)
Query 24 VMLCVMLGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGFLSQ 83
V + + L T L+++ N A+ + +W + SF +A ++++ +TG L+Q
Sbjct 19 VTIALSLATFMQMLDSTISNVAIPTISGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQ 78
Query 84 RFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGIIFSVTSQQ 143
R G+ ++L ++ F L+S + + + + ++ R VQG +G +IPLS ++ +
Sbjct 79 RIGELRLFLLSVTFFSLSSLMCSLSTNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPPE 138
Query 144 KRGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWIHLP-KQT 202
KR A LW +++ CGP+LG + + W +FL+N+P G++ L L L ++T
Sbjct 139 KRTFALALWSMTVIIAPICGPILGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRET 198
Query 203 KNRSERFDWFAYSLLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGLWFWIITRK 262
+ + + +LL + L + L + + L S +L ++S++S + I
Sbjct 199 ETSPVKMNLPGLTLLVLGVGGLQIMLDKGRDLDWFNSSTIIILTVVSVISLISLVIWEST 258
Query 263 QQSSLIKWQIFNSQGFNYSLFISVMHTTGLFIS--LLVIPLFIQNTLKLSPIWTGILLMT 320
++ ++ +F S+ N+++ I + LF S ++++P +Q T+ + IW G+
Sbjct 259 SENPILDLSLFKSR--NFTIGIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAP 316
Query 321 SALTTSLCSKWAGEFLDQHGAKFLISFGIILTALAFI--GLALGGHLPLTYLIVCMALHG 378
+ L S G + ++ + L++F ++ A+ + + + T +I+ G
Sbjct 317 IGIMPLLISPLIGRYGNKIDMRLLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQG 376
Query 379 LGFGLSYMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAV 419
++P TT + L D + ++++N R +V
Sbjct 377 FAVACFFLPLTTISFSGLPDNKF-ANASSMSNFFRTLSGSV 416
>P0AEJ0 Multidrug export protein EmrB [Escherichia coli (strain
K12)]
Length=512
Score = 127 bits (320), Expect = 6e-35
Identities = 88/401 (22%), Positives = 184/401 (46%), Gaps = 4/401 (1%)
Query 26 LCVMLGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGFLSQRF 85
+ + L T L+++ N A+ + + + +W + SF +A ++S+ LTG+L++R
Sbjct 17 IALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAISIPLTGWLAKRV 76
Query 86 GKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGIIFSVTSQQKR 145
G+ +++L + F +AS G + ++ R +QG +G +IPLS ++ + KR
Sbjct 77 GEVKLFLWSTIAFAIASWACGVSSSLNMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAKR 136
Query 146 GAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWIHL-PKQTKN 204
A LW +++ CGP+LG + + W +F +N+P GV +++ L ++T+
Sbjct 137 SIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETRT 196
Query 205 RSERFDWFAYSLLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGLWFWIITRKQQ 264
R D +LL I SL + L + K L S + +L ++++++ + +
Sbjct 197 ERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTDD 256
Query 265 SSLIKWQIFNSQGFNYSLFISVMHTTGLFISLLVIPLFIQNTLKLSPIWTGILLMTSALT 324
+ ++ +F S+ F + F +++++P +Q + W G+ +
Sbjct 257 NPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGII 316
Query 325 TSLCSKWAGEFLDQHGAKFLISFGIILTALAFIGLALGGHLPLTYLIVCMALHGLGFGLS 384
+ S G F + + L++F I+ A+ F A + + GF ++
Sbjct 317 PVILSPIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGFAVA 376
Query 385 --YMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAVAVVI 423
+MP TT L+ L + L ++++N R ++ I
Sbjct 377 CFFMPLTTITLSGLPPERLAA-ASSLSNFTRTLAGSIGTSI 416
>P42670 Puromycin resistance protein pur8 [Streptomyces alboniger]
Length=503
Score = 125 bits (313), Expect = 4e-34
Identities = 111/418 (27%), Positives = 190/418 (45%), Gaps = 16/418 (4%)
Query 3 DISRVHATQHSCDEKSMISRWVMLCVMLGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSW 62
DIS V +C W ++ ++ V L+ + N AL + D + + + W
Sbjct 6 DISAVPVESAACQGPDPRRWWGLVVILAAQLLVVLDGTVVNIALPSVQRDLGMSDTSRQW 65
Query 63 FMVSFLLAMSLSLLLTGFLSQRFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQG 122
+ ++ LA LLL G ++ FG+R ++ + F LAS +GG A T+ RA+QG
Sbjct 66 VITAYTLAFGGLLLLGGRVADAFGRRRIFAVGILGFGLASLLGGAAPDPGTLFLARALQG 125
Query 123 FASGLMIPLSLGIIFSV-TSQQKRGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFL 181
+ + P +L +I ++ T +RG A G++GA+ A G + G +L + DW
Sbjct 126 VFAAALAPAALALINTLFTEPGERGKAFGVYGAVSGGGAAVGLLAGGLLTEYLDWRWCLY 185
Query 182 VNIPFGVLALVLGWIHLPKQTK-NRSERFDWFAYSLLSASIISLLLALSQVKTLSDLESF 240
VN P +LAL LG LP+ + R+ R D L +++++ A ++ + S
Sbjct 186 VNAPVALLAL-LGCRLLPRDRRTGRAVRLDLPGTLLGCGGLVAIVYAFAEAE--SGWGDP 242
Query 241 KFFLLILISILSGLWFWIITRKQQSSLIKWQIFNSQGFNYSLFISVMHTTGLFISLLVIP 300
L+++ +L + F ++ R+ Q L+ + + S + + GLF L +
Sbjct 243 LVVRLLVLGVLMLVAFALVERRVQDPLLPPGVVAHRVRGGSFLVVGLPQIGLFGLFLFLT 302
Query 301 LFIQNTLKLSPIWTGILLMTSALTTSLCSKW-AGEFLDQHGAKFLISFGIILTALAFIGL 359
++Q L SP+ TG+ + L ++ S A L + + LI G +L A A G+
Sbjct 303 YYLQGILDYSPVLTGVAFLPLGLGIAVGSSLIAARLLPRTRPRTLI-VGALLAAAA--GM 359
Query 360 ALGGHLP-------LTYLIVCMALHGLGFGLSYMPATTAGLNSLSDQELVTQGAAINN 410
AL L LT+L+ L GLG G MPA ++ E A +N+
Sbjct 360 ALLTRLEPDTPQVYLTHLLPAQILIGLGIGCMMMPAMHTATARVAPHEAGAAAAVVNS 417
>Q00538 Methylenomycin A resistance protein [Bacillus subtilis
(strain 168)]
Length=466
Score = 124 bits (310), Expect = 7e-34
Identities = 92/412 (22%), Positives = 192/412 (47%), Gaps = 10/412 (2%)
Query 24 VMLCVMLGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGFLSQ 83
V++ + LG +L+ + N A+ + + ++ + V+W + ++L + LL G L+
Sbjct 18 VLIVLALGFLMATLDVTVVNVAMADMKNTLSMSLSGVTWVVDGYILTFASLLLAGGALAD 77
Query 84 RFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGII-FSVTSQ 142
RFG + +Y+ LA+FV+AS + + + + ++A R +QG + L +P SL ++ S +
Sbjct 78 RFGSKTIYILGLAVFVMASCLCAASINGQMLIAGRLIQGIGAALFMPSSLSLLAASYLDE 137
Query 143 QKRGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWIHLPKQT 202
+ R GLW A++ A GP +G VL+ W ++FL+N+P G AL+ + + +
Sbjct 138 RARARMFGLWAALVSAASALGPFIGGVLVQLAGWQSIFLINVPIGAAALISAY-RILSRV 196
Query 203 KNRSERFDWFAYSLLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGLWFWIITRK 262
+S R + + L ++ L AL Q + + S + ++L+ + F +
Sbjct 197 PGKSSRVNIIGHLLGMMALGFLSYALIQGPS-AGWRSPVILVAFTAAVLAFVLFLLREIS 255
Query 263 QQSSLIKWQIFNSQGFNYSLFISVMHTTGLFISLLVIPLFIQNTLKLSPIWTGI----LL 318
++ ++ ++ + F+ + FI + LF + ++ LF+Q S G+ ++
Sbjct 256 AKTPILPASLYKNGRFSAAQFIGFLLNFALFGGMFMLSLFLQEAGGASSFMAGVELLPMM 315
Query 319 MTSALTTSLCSKWAGEFLDQHGAKFLISFGIILTALAFIGLALGGHLPLTYLIVCMALHG 378
+ L ++ A F + G +S + + + + P L V M++
Sbjct 316 AVFVIGNLLFARLANRF--EAGQLMFVSMAVSCIIALLLFVLISPDFPYWQLAVLMSVMN 373
Query 379 LGFGLSYMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAVAVVIAALYLQI 430
L G++ TT + + + GAA+ N R+ + V V I + + +
Sbjct 374 LCTGITVPAMTTVIMQAAGQRHTNIAGAAL-NANRQIGALVGVAITGVIIHL 424
>P39886 Tetracenomycin C resistance and export protein [Streptomyces
glaucescens]
Length=538
Score = 124 bits (311), Expect = 1e-33
Identities = 98/398 (25%), Positives = 179/398 (45%), Gaps = 17/398 (4%)
Query 25 MLCVMLGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGFLSQR 84
+L V +G V+L+++ A + D + A V W +LLA+++SL+ G L R
Sbjct 28 LLAVAVGVMMVALDSTIVAIANPAIQQDLHASLADVQWITNGYLLALAVSLITAGKLGDR 87
Query 85 FGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGIIFSVTSQQK 144
FG R+ +L +A F + SA G + ++ R +QG LM P +LG++ K
Sbjct 88 FGHRQTFLVGVAGFAVTSAAIGLSGSVAAIVVFRVLQGLFGALMQPSALGLLRVTFPPGK 147
Query 145 RGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWIHLPKQTKN 204
A G+W ++ + A GP++G +L+ W A+F +N+P G+ ALV G + L
Sbjct 148 LNMAIGIWSGVVGASTAAGPIIGGLLVQHVGWEAVFFINVPVGLAALVAGLVILTDARAE 207
Query 205 RSER-FDWFAYSLLSASIISLLLALSQVKT--LSDLESFKFFLLILISILSGLWFWIITR 261
R+ + FD LLS ++ L+ L + DL + F + ++L+ F +
Sbjct 208 RAPKSFDVSGIVLLSGAMFCLVWGLIKAPAWGWGDLRTLGF---LAAAVLAFAGFTLRES 264
Query 262 KQQSSLIKWQIFNSQGFNYSLFISVMHTTGLFISLLVIPLFIQNTLKLSPIWTGILLMTS 321
+ L+ +F S + + V+ L + ++QN +SP+ +G+ L+
Sbjct 265 RATEPLMPLAMFRSVPLSAGTVLMVLMAFSFIGGLFFVTFYLQNVHGMSPVESGVHLLPL 324
Query 322 ALTTSLCSKWAGEFLDQHGAKFLISFGIILTALAFIGLA-LGGHLPLTYLIVCMALHGLG 380
+ + +G + + G + G++LTA + G++ L + + L GLG
Sbjct 325 TGMMIVGAPVSGIVISRFGPGGPLVVGMLLTAASLWGMSTLEADSGMGITSLWFVLLGLG 384
Query 381 FG----------LSYMPATTAGLNSLSDQELVTQGAAI 408
+S PA AG+ Q + G ++
Sbjct 385 LAPVMVGTTDVIVSNAPAELAGVAGGLQQSAMQVGGSL 422
>P36554 Putative multidrug resistance protein MdtD [Escherichia
coli (strain K12)]
Length=471
Score = 121 bits (303), Expect = 7e-33
Identities = 107/469 (23%), Positives = 214/469 (46%), Gaps = 18/469 (4%)
Query 21 SRWVMLCVMLGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGF 80
+RW + V G SL+ + N AL + + +VS++L +++ L +G+
Sbjct 8 TRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGW 67
Query 81 LSQRFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGIIFSVT 140
L+ + G R ++ A+ LF L S + +L RA+QG +M+P+ + +
Sbjct 68 LADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELLLARALQGVGGAMMVPVGRLTVMKIV 127
Query 141 SQQKRGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWIHLPK 200
+++ AA + GP LG +L+ + W +FL+NIP G++ + + +P
Sbjct 128 PREQYMAAMTFVTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLLLMPN 187
Query 201 QTKNRSERFDWFAYSLLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGLWFWIIT 260
T ++ RFD + LL+ + L LAL K + L L+ + +++ + + +
Sbjct 188 YTM-QTRRFDLSGFLLLAVGMAVLTLALDGSKG-TGLSPLTIAGLVAVGVVALVLYLLHA 245
Query 261 RKQQSSLIKWQIFNSQGFNYSLFISVMHTTGLFISLLVIPLFIQNTLKLSPIWTGILLMT 320
R +L ++F ++ F+ L S G + + P+F+Q L SP G++++
Sbjct 246 RNNNRALFSLKLFRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIP 305
Query 321 SALTTSLCSKWAGEFLDQHGAKFLI---SFGIILTALAFIGLA-LGGHLPLTYLIVCMAL 376
L + + + +++ G + ++ + G+ L L F+ A LG + L +++ L
Sbjct 306 MVLGSMGMKRIVVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLF---L 362
Query 377 HGLGFGLSYMPATTAGLNSLSDQELVTQGAAINNLLRRTCSAVAVVIAALYLQIRTHSLL 436
G+ + T L L D L + G ++ +++ + ++ V IA L L + S
Sbjct 363 QGMVNSTRFSSMNTLTLKDLPD-NLASSGNSLLSMIMQLSMSIGVTIAGLLLGL-FGSQH 420
Query 437 ASYDLDRAQLTSIRELFLICAALLLLALPYAWKFPYSK-PLDAHRSSKI 484
S D Q ++ + L++ALP F +++ P D H++ I
Sbjct 421 VSVDSGTTQTVF---MYTWLSMALIIALP---AFIFARVPNDTHQNVAI 463
>P0A0J9 Antiseptic resistance protein [Staphylococcus aureus]
Length=514
Score = 113 bits (283), Expect = 4e-30
Identities = 91/379 (24%), Positives = 181/379 (48%), Gaps = 16/379 (4%)
Query 22 RWVMLCVM-LGTGTVSLNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGF 80
RW L V+ + V+++ + AL +L+ + W + + L ++ ++
Sbjct 17 RWTALVVLAVSLFVVTMDMTILIMALPELVRELEPSGTQQLWIVDIYSLVLAGFIIPLSA 76
Query 81 LSQRFGKREVYLGALALFVLASAIGGCAKHYETVLAVRAVQGFASGLMIPLSLGIIFSVT 140
+ ++G+++ L ALF L S A+ E V+A+R + G A L++P +L +I +
Sbjct 77 FADKWGRKKALLTGFALFGLVSLAIFFAESAEFVIAIRFLLGIAGALIMPTTLSMIRVIF 136
Query 141 SQQK-RGAATGLWGAMIMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWIHLP 199
K R A +W + GP++G LL + W + FL+N+PF ++A+V G LP
Sbjct 137 ENPKERATALAVWSIASSIGAVFGPIIGGALLEQFSWHSAFLINVPFAIIAVVAGLFLLP 196
Query 200 --KQTKNRSERFDWFAYSLLSASIISLLLALSQV--KTLSDLESFKFFLLILISILSGLW 255
K +K +S +D + L A +I L+ ++ + + L+D+ + +L + I+
Sbjct 197 ESKLSKEKSHSWDIPSTILSIAGMIGLVWSIKEFSKEGLADIIPWVVIVLAITMIV---- 252
Query 256 FWIITRKQQSS---LIKWQIFNSQGFNYSLFISVMHTTGLFISLLVIPLFIQNTLKLSPI 312
I ++ SS ++ ++F + F+ + M + LL+ ++Q +LSP
Sbjct 253 --IFVKRNLSSSDPMLDVRLFKKRSFSAGTIAAFMTMFAMASVLLLASQWLQVVEELSPF 310
Query 313 WTGILLMTSALTTSLCSKWAGEFLDQHGAKFLISFGIILTALAFIGLALGGHLPLTYLIV 372
G+ L+ A+ + + A + G K ++ GI + A+ + GH PL+Y +
Sbjct 311 KAGLYLLPMAIGDMVFAPIAPGLAARFGPKIVLPSGIGIAAIGMFIMYFFGH-PLSYSTM 369
Query 373 CMALHGLGFGLSYMPATTA 391
+AL +G G++ + +A
Sbjct 370 ALALILVGAGMASLAVASA 388
Lambda K H a alpha
0.329 0.140 0.432 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 3718668
Database: 95010f4dc84bdb1b85ac2b8192d7f2e9.SwissProt.fasta
Posted date: Jun 1, 2024 7:38 PM
Number of letters in database: 9,654
Number of sequences in database: 19
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
