BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: f52c1c9468f2666c714994d232747058.SwissProt.fasta
17 sequences; 22,294 total letters
Query= ACIAD2156
Length=1175
Score E
Sequences producing significant alignments: (Bits) Value
A6ZRZ0 Stress response protein NST1 [Saccharomyces cerevisiae (st... 57.8 7e-11
P53935 Stress response protein NST1 [Saccharomyces cerevisiae (st... 57.8 7e-11
A0JMT0 Chromatin assembly factor 1 subunit A-B [Xenopus laevis] 57.4 8e-11
Q8CIS9 Keratin, type I cytoskeletal 9 [Rattus norvegicus] 55.5 3e-10
Q5U4E6 Golgin subfamily A member 4 [Rattus norvegicus] 53.1 2e-09
Q10475 Eukaryotic translation initiation factor 4 gamma [Schizosa... 52.0 4e-09
Q80UF4 Serologically defined colon cancer antigen 8 homolog [Mus ... 50.1 1e-08
Q65SK9 Translation initiation factor IF-2 [Mannheimia succinicipr... 48.5 4e-08
Q9BV73 Centrosome-associated protein CEP250 [Homo sapiens] 48.5 5e-08
P61584 Rho-associated protein kinase 1 [Pan troglodytes] 47.8 8e-08
Q13464 Rho-associated protein kinase 1 [Homo sapiens] 47.8 8e-08
O75962 Triple functional domain protein [Homo sapiens] 45.4 4e-07
A8FYS0 Translation initiation factor IF-2 [Shewanella sediminis (... 43.5 1e-06
P0CP34 Stress response protein NST1 [Cryptococcus neoformans var.... 43.5 2e-06
P0CP35 Stress response protein NST1 [Cryptococcus neoformans var.... 43.5 2e-06
O88735 Ensconsin [Mus musculus] 40.0 2e-05
Q12QI1 Translation initiation factor IF-2 [Shewanella denitrifica... 34.7 8e-04
>A6ZRZ0 Stress response protein NST1 [Saccharomyces cerevisiae
(strain YJM789)]
Length=1240
Score = 57.8 bits (138), Expect = 7e-11
Identities = 50/197 (25%), Positives = 105/197 (53%), Gaps = 14/197 (7%)
Query 717 KKDEKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLKK--ALEDIEKAKIS 774
++++++K+ K+ K +RE E+E K + + A EEEK + + +K +++E+ ++
Sbjct 632 EEEKRKKREKEEKKQKKREKEKEKKRLQQL----AKEEEKRKREEEKERLKKELEEREMR 687
Query 775 DAEKAQLKVKAEKVASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQF 834
E + KV+ K D+ + R E+ ++ +E++E++ E+ +R + EK I+ Q
Sbjct 688 RREAQRKKVEEAKRKKDEERKRRLEEQQRREEMQEKQ-RKQKEELKRKREEEKKRIREQ- 745
Query 835 DANKISNAQKVQMEKQLEDQLRAIKRNGLEERLKLEEQYSS--ISGKSGNQSRITNDIAN 892
K +K+Q EK+ E++ R I + L ++ EEQ S+ +S K ++ + N +++
Sbjct 746 ---KRLEQEKLQKEKEEEERQRLIAEDALRKQKLNEEQTSANILSAKPFTENGVGNPVSS 802
Query 893 LDTDQKVANTQSFNLMS 909
+ + N Q N S
Sbjct 803 -QSHPNMTNYQEDNSCS 818
>P53935 Stress response protein NST1 [Saccharomyces cerevisiae
(strain ATCC 204508 / S288c)]
Length=1240
Score = 57.8 bits (138), Expect = 7e-11
Identities = 50/197 (25%), Positives = 105/197 (53%), Gaps = 14/197 (7%)
Query 717 KKDEKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLKK--ALEDIEKAKIS 774
++++++K+ K+ K +RE E+E K + + A EEEK + + +K +++E+ ++
Sbjct 632 EEEKRKKREKEEKKQKKREKEKEKKRLQQL----AKEEEKRKREEEKERLKKELEEREMR 687
Query 775 DAEKAQLKVKAEKVASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQF 834
E + KV+ K D+ + R E+ ++ +E++E++ E+ +R + EK I+ Q
Sbjct 688 RREAQRKKVEEAKRKKDEERKRRLEEQQRREEMQEKQ-RKQKEELKRKREEEKKRIREQ- 745
Query 835 DANKISNAQKVQMEKQLEDQLRAIKRNGLEERLKLEEQYSS--ISGKSGNQSRITNDIAN 892
K +K+Q EK+ E++ R I + L ++ EEQ S+ +S K ++ + N +++
Sbjct 746 ---KRLEQEKLQKEKEEEERQRLIAEDALRKQKLNEEQTSANILSAKPFTENGVGNPVSS 802
Query 893 LDTDQKVANTQSFNLMS 909
+ + N Q N S
Sbjct 803 -QSHPNMTNYQEDNSCS 818
>A0JMT0 Chromatin assembly factor 1 subunit A-B [Xenopus laevis]
Length=885
Score = 57.4 bits (137), Expect = 8e-11
Identities = 81/316 (26%), Positives = 124/316 (39%), Gaps = 65/316 (21%)
Query 651 VKTTWNDAASKAGTSWKTAWENISGASE--KGGKKFQLLFLKDPNATDESPKPSPLPTFN 708
VK +N +A S ++ +S +S + G KF SP S PT
Sbjct 198 VKEDYNSSADDDSVSVSSSSSPVSLSSPDVQTGSKF---------TNGSSPSTSTTPT-- 246
Query 709 PNRGIGTGKKDEKEKKPKKGKSD---AERE----AEREAKAIADI-RYKYATEEEKIQLD 760
G T K EKK K K++ AE+E A REA+A D+ + K E E+ + D
Sbjct 247 ---GKATSNKTSAEKKKTKDKAEKRQAEKEERECARREARAAKDLAKKKREGEREQREKD 303
Query 761 LKKALEDIEKAKISDAEKAQLKVKAEKVASDKIKALRAEQFEKIK---EIREQEIANAIE 817
K EK + D EKA+ E+ +K++AL A+Q EK K E R++E ++
Sbjct 304 KK------EKKEREDREKAEKNRLKEEKKKEKLEALEAKQEEKRKKEEEKRQKEEEKRLK 357
Query 818 QAQRIFDIEKASIQAQFDANKISNAQK-------------------------VQMEKQLE 852
+ ++ EKA I K A K + E++
Sbjct 358 EEEKRIKAEKAEITRFLQKPKTPQAPKTFARSCGKFAPFEIKKGMALAPLCRIDFEQEAS 417
Query 853 DQLRAIKRNGLEERLKLEEQYSSISGKSGNQSRITNDIANLDTDQKVANTQ---SFNLMS 909
++L + E L+E K G + T + +D Q + T N++
Sbjct 418 EELDIFLQEQTSESSFLDEIKKRRPRKMGQTTVPTINSVEVDDVQVLGETDPVLGSNMVL 477
Query 910 EAQMKDF----EKKFG 921
E +KD KKFG
Sbjct 478 EEHIKDIGVPERKKFG 493
>Q8CIS9 Keratin, type I cytoskeletal 9 [Rattus norvegicus]
Length=618
Score = 55.5 bits (132), Expect = 3e-10
Identities = 59/266 (22%), Positives = 116/266 (44%), Gaps = 26/266 (10%)
Query 17 SLSEGMNQATNNVQSAANDINRIADSIKTAFDGVRDSLKNIDVSLNIDMSA--------V 68
SL +G++ N +Q +DIN ++ FD + D LK + S +M+ V
Sbjct 233 SLPQGVDADINGLQKVLDDINMEKSDLEIQFDSLDDELKALKKSHKEEMNQLTGLNDGDV 292
Query 69 QQRLSSAANTIKTQI-NNIVDDASIKLKIDTTSLSSEIEHAENLIRSRLSSLPIQNVKLD 127
++ A +T TQ+ N++ ++ + + + E I +L++ +++
Sbjct 293 NVEINVAPSTDLTQVLNDMREEYEHLISKNRQDIEQHYESQMTQIEHQLTN---SGPEME 349
Query 128 IDIHEIQRRLNLITGQQVKIKLGLDT-STLQAQLHQAKNTITTMLQSTLSSAIRITVNLP 186
++ ++ + + + ++++ L T S L+ L KN LQ +I +
Sbjct 350 TNMKQVSQLQHSVQELNIELQTQLTTKSALEKALEDTKNRYCGQLQ-------QIREQIS 402
Query 187 LLAAQLSQAKAMINRALSQLNGSNINLNTVIN--IDATSTMLRSSLDRLKTSVDHLRNRL 244
+ AQL+Q +A +Q G +++ T + I+ +L ++S ++
Sbjct 403 EMEAQLAQVRAE-TECQNQEYGLLLSIKTRLEKEIETYRKLLEGGQQDFESSG---AGQI 458
Query 245 GSGGGGGGGSGSGGGSGSGVGTSFLG 270
G G G GG GSGG G G G S+ G
Sbjct 459 GFGSGKGGQRGSGGSYGGGSGDSYEG 484
Score = 40.8 bits (94), Expect = 9e-06
Identities = 32/112 (29%), Positives = 52/112 (46%), Gaps = 14/112 (13%)
Query 241 RNRLGSGGGGGGGSGSGGGSGSGVGTSFLG------NFLANIGSELVLQ-ISSLTGELIR 293
R G G GGG G GSGGG G G G F G + N ++V+Q ++S +
Sbjct 95 RGCFGGGSGGGFGGGSGGGFGGGFGGGFGGGSGGGEGSILNTNEKVVMQNLNSRLASYMD 154
Query 294 NARELENMSRLANSTTLEFQEWAFASKSVGISQEKLG---DIMKDVNDKFGD 342
+ELE + + + QEW ++ K + Q+ + ++D+ D+ D
Sbjct 155 KVQELEEDNA---NLEKQIQEW-YSRKGNRVFQKDYSHYYNTIEDLKDRIVD 202
Score = 37.0 bits (84), Expect = 1e-04
Identities = 16/21 (76%), Positives = 16/21 (76%), Gaps = 0/21 (0%)
Query 245 GSGGGGGGGSGSGGGSGSGVG 265
GSGG GGGSGSGGGSG G
Sbjct 580 GSGGSYGGGSGSGGGSGGSYG 600
Score = 33.9 bits (76), Expect = 0.001
Identities = 15/21 (71%), Positives = 15/21 (71%), Gaps = 0/21 (0%)
Query 245 GSGGGGGGGSGSGGGSGSGVG 265
GSGG GGGSGSGG SG G
Sbjct 539 GSGGSYGGGSGSGGESGGSYG 559
Score = 33.5 bits (75), Expect = 0.002
Identities = 19/52 (37%), Positives = 25/52 (48%), Gaps = 0/52 (0%)
Query 221 ATSTMLRSSLDRLKTSVDHLRNRLGSGGGGGGGSGSGGGSGSGVGTSFLGNF 272
A+ +RSS R + R SG GGGG S G G G G+S+ G +
Sbjct 26 ASRGSMRSSFGRSSRAGGESRFGSSSGFGGGGFSACGTGGGGSFGSSYGGGY 77
Score = 31.2 bits (69), Expect = 0.008
Identities = 18/30 (60%), Positives = 19/30 (63%), Gaps = 4/30 (13%)
Query 245 GSGG---GGGGGS-GSGGGSGSGVGTSFLG 270
GSGG GG GGS G G GSG G G S+ G
Sbjct 572 GSGGSYEGGSGGSYGGGSGSGGGSGGSYGG 601
Score = 30.8 bits (68), Expect = 0.011
Identities = 17/32 (53%), Positives = 18/32 (56%), Gaps = 6/32 (19%)
Query 245 GSGGGGGGGSG------SGGGSGSGVGTSFLG 270
GSGG GGGSG SGG G G G S+ G
Sbjct 515 GSGGSYGGGSGGSHGGKSGGSHGGGSGGSYGG 546
Score = 30.4 bits (67), Expect = 0.014
Identities = 15/20 (75%), Positives = 15/20 (75%), Gaps = 2/20 (10%)
Query 246 SGGGGGGGSGS--GGGSGSG 263
SGG GGGSG GGGSGSG
Sbjct 532 SGGSHGGGSGGSYGGGSGSG 551
Score = 30.4 bits (67), Expect = 0.014
Identities = 16/27 (59%), Positives = 17/27 (63%), Gaps = 1/27 (4%)
Query 245 GSGGGGGGGS-GSGGGSGSGVGTSFLG 270
GS GGG GGS G G GSG G S+ G
Sbjct 534 GSHGGGSGGSYGGGSGSGGESGGSYGG 560
Score = 28.9 bits (63), Expect = 0.042
Identities = 12/19 (63%), Positives = 13/19 (68%), Gaps = 0/19 (0%)
Query 245 GSGGGGGGGSGSGGGSGSG 263
G+GGGG GS GGG G G
Sbjct 62 GTGGGGSFGSSYGGGYGRG 80
Score = 28.9 bits (63), Expect = 0.042
Identities = 13/24 (54%), Positives = 13/24 (54%), Gaps = 0/24 (0%)
Query 247 GGGGGGGSGSGGGSGSGVGTSFLG 270
GGG G GSGG G G G S G
Sbjct 507 GGGSSSGGGSGGSYGGGSGGSHGG 530
Score = 28.9 bits (63), Expect = 0.042
Identities = 12/21 (57%), Positives = 12/21 (57%), Gaps = 0/21 (0%)
Query 245 GSGGGGGGGSGSGGGSGSGVG 265
GS GGG G GGGSG G
Sbjct 509 GSSSGGGSGGSYGGGSGGSHG 529
Score = 28.5 bits (62), Expect = 0.055
Identities = 11/17 (65%), Positives = 11/17 (65%), Gaps = 0/17 (0%)
Query 247 GGGGGGGSGSGGGSGSG 263
GGG G G GSGG G G
Sbjct 586 GGGSGSGGGSGGSYGGG 602
Score = 28.1 bits (61), Expect = 0.072
Identities = 13/22 (59%), Positives = 13/22 (59%), Gaps = 0/22 (0%)
Query 246 SGGGGGGGSGSGGGSGSGVGTS 267
S GGG GGS GG GS G S
Sbjct 511 SSGGGSGGSYGGGSGGSHGGKS 532
Score = 28.1 bits (61), Expect = 0.072
Identities = 13/24 (54%), Positives = 13/24 (54%), Gaps = 0/24 (0%)
Query 247 GGGGGGGSGSGGGSGSGVGTSFLG 270
GGG G G SGG G G G S G
Sbjct 545 GGGSGSGGESGGSYGGGSGGSHGG 568
Score = 28.1 bits (61), Expect = 0.072
Identities = 12/21 (57%), Positives = 12/21 (57%), Gaps = 0/21 (0%)
Query 245 GSGGGGGGGSGSGGGSGSGVG 265
GSG GG G GGGSG G
Sbjct 547 GSGSGGESGGSYGGGSGGSHG 567
Score = 27.7 bits (60), Expect = 0.094
Identities = 18/40 (45%), Positives = 20/40 (50%), Gaps = 6/40 (15%)
Query 245 GSGGGGGGGS------GSGGGSGSGVGTSFLGNFLANIGS 278
GS GGG GGS GSGG G G S+ G + GS
Sbjct 556 GSYGGGSGGSHGGQKGGSGGSYEGGSGGSYGGGSGSGGGS 595
Score = 27.3 bits (59), Expect = 0.12
Identities = 11/19 (58%), Positives = 11/19 (58%), Gaps = 0/19 (0%)
Query 245 GSGGGGGGGSGSGGGSGSG 263
G G GGGSG G GSG
Sbjct 507 GGGSSSGGGSGGSYGGGSG 525
Score = 27.3 bits (59), Expect = 0.12
Identities = 15/27 (56%), Positives = 15/27 (56%), Gaps = 2/27 (7%)
Query 246 SGGGGGG--GSGSGGGSGSGVGTSFLG 270
SGGG GG G GSGG G G S G
Sbjct 512 SGGGSGGSYGGGSGGSHGGKSGGSHGG 538
Score = 27.3 bits (59), Expect = 0.12
Identities = 15/26 (58%), Positives = 16/26 (62%), Gaps = 1/26 (4%)
Query 246 SGGGGGGGSG-SGGGSGSGVGTSFLG 270
SGG GGGSG S GG G G S+ G
Sbjct 554 SGGSYGGGSGGSHGGQKGGSGGSYEG 579
Score = 26.6 bits (57), Expect = 0.21
Identities = 14/25 (56%), Positives = 15/25 (60%), Gaps = 3/25 (12%)
Query 245 GSGGGGGGGS---GSGGGSGSGVGT 266
GS GG GGS GSGG G G G+
Sbjct 526 GSHGGKSGGSHGGGSGGSYGGGSGS 550
Score = 26.6 bits (57), Expect = 0.21
Identities = 11/19 (58%), Positives = 11/19 (58%), Gaps = 0/19 (0%)
Query 245 GSGGGGGGGSGSGGGSGSG 263
G G G GG SG G GSG
Sbjct 545 GGGSGSGGESGGSYGGGSG 563
Score = 26.6 bits (57), Expect = 0.21
Identities = 10/16 (63%), Positives = 11/16 (69%), Gaps = 0/16 (0%)
Query 245 GSGGGGGGGSGSGGGS 260
GSG GGG G GGG+
Sbjct 588 GSGSGGGSGGSYGGGN 603
Score = 26.2 bits (56), Expect = 0.28
Identities = 14/36 (39%), Positives = 18/36 (50%), Gaps = 0/36 (0%)
Query 242 NRLGSGGGGGGGSGSGGGSGSGVGTSFLGNFLANIG 277
+R G G SG GGG S GT G+F ++ G
Sbjct 39 SRAGGESRFGSSSGFGGGGFSACGTGGGGSFGSSYG 74
Score = 26.2 bits (56), Expect = 0.28
Identities = 16/36 (44%), Positives = 16/36 (44%), Gaps = 3/36 (8%)
Query 245 GSGGGGGGGSGSG---GGSGSGVGTSFLGNFLANIG 277
GS G GGS G GGSG G G G F G
Sbjct 84 GSSSGMFGGSSRGCFGGGSGGGFGGGSGGGFGGGFG 119
Score = 26.2 bits (56), Expect = 0.28
Identities = 14/25 (56%), Positives = 14/25 (56%), Gaps = 2/25 (8%)
Query 245 GSGGGGGG--GSGSGGGSGSGVGTS 267
GSGG GG G GSGG G G S
Sbjct 549 GSGGESGGSYGGGSGGSHGGQKGGS 573
Score = 26.2 bits (56), Expect = 0.28
Identities = 10/18 (56%), Positives = 11/18 (61%), Gaps = 0/18 (0%)
Query 245 GSGGGGGGGSGSGGGSGS 262
G G G GGGSG G G+
Sbjct 586 GGGSGSGGGSGGSYGGGN 603
Score = 25.4 bits (54), Expect = 0.48
Identities = 11/20 (55%), Positives = 13/20 (65%), Gaps = 0/20 (0%)
Query 241 RNRLGSGGGGGGGSGSGGGS 260
R+ GS GGGGG G+ GS
Sbjct 11 RSSSGSSCGGGGGRGASRGS 30
Score = 25.4 bits (54), Expect = 0.48
Identities = 12/21 (57%), Positives = 12/21 (57%), Gaps = 0/21 (0%)
Query 247 GGGGGGGSGSGGGSGSGVGTS 267
G GGGG GS G G G G S
Sbjct 62 GTGGGGSFGSSYGGGYGRGFS 82
Score = 25.4 bits (54), Expect = 0.48
Identities = 14/56 (25%), Positives = 30/56 (54%), Gaps = 14/56 (25%)
Query 814 NAIEQAQRIFDIEKASIQAQFDANKISNAQKVQMEKQLEDQLRAIKRNGLEERLKL 869
N +++ ++EK+ ++ QFD+ L+D+L+A+K++ EE +L
Sbjct 243 NGLQKVLDDINMEKSDLEIQFDS--------------LDDELKALKKSHKEEMNQL 284
Score = 23.9 bits (50), Expect = 1.4
Identities = 9/18 (50%), Positives = 10/18 (56%), Gaps = 0/18 (0%)
Query 245 GSGGGGGGGSGSGGGSGS 262
G G GGG GS GG +
Sbjct 587 GGSGSGGGSGGSYGGGNT 604
Score = 23.1 bits (48), Expect = 2.5
Identities = 10/20 (50%), Positives = 10/20 (50%), Gaps = 0/20 (0%)
Query 243 RLGSGGGGGGGSGSGGGSGS 262
R SG GGG G G GS
Sbjct 11 RSSSGSSCGGGGGRGASRGS 30
>Q5U4E6 Golgin subfamily A member 4 [Rattus norvegicus]
Length=2259
Score = 53.1 bits (126), Expect = 2e-09
Identities = 47/197 (24%), Positives = 103/197 (52%), Gaps = 30/197 (15%)
Query 752 TEEEKIQLDLKKALEDIEKAK-ISDAEKAQL-------KVKAEKVASDK---IKALRAEQ 800
+E+E +Q L++ L+++EK K + AEK +L K E++ DK I + +
Sbjct 361 SEKEALQEQLEERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVITEAKRQM 420
Query 801 FEKIKEIREQEIANAIEQAQR-------IFDIEKASIQAQFD--ANKISNAQKVQ----- 846
E + E+++ EIA QR + + ++ S +A F+ +S AQK +
Sbjct 421 LETL-ELKDDEIAQLRSHIQRMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRR 479
Query 847 MEKQLEDQLRAIKRNGLEERLKLEEQYSSISGKSGNQSRITN----DIANLDTDQKVANT 902
M+ ++++Q++A++R G EERL+L+ + S + ++ + ++ + D+ L +Q +
Sbjct 480 MKVEMDEQIKAVERAGEEERLRLQHELSRVRQEAVSMAKKNSEQRADLQKLHAEQLASKE 539
Query 903 QSFNLMSEAQMKDFEKK 919
Q + E++ ++ +++
Sbjct 540 QELSQKLESRERELQEQ 556
Score = 38.1 bits (87), Expect = 7e-05
Identities = 40/235 (17%), Positives = 106/235 (45%), Gaps = 25/235 (11%)
Query 726 KKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQLKVKA 785
++ K +ER A E + K + ++++++ + ++ +E+A + E+ +L+ +
Sbjct 449 REQKEKSERAAFEELEKALSTAQKTEDAQRRMKVEMDEQIKAVERA--GEEERLRLQHEL 506
Query 786 EKVASDKIKALR--AEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFD---ANKIS 840
+V + + + +EQ ++++ +++A+ ++ + + + +Q Q S
Sbjct 507 SRVRQEAVSMAKKNSEQRADLQKLHAEQLASKEQELSQKLESRERELQEQMRMALEKSRS 566
Query 841 NAQKVQMEKQLEDQLRAIKRNGLEERLKLEEQYSSISG----KSGNQSRITNDIANLDTD 896
K+ EK+ ++ L A++ L+++ L E + + G +++RI +L+
Sbjct 567 EYLKLTQEKEQQESL-ALEELELQKKAILTESENKLQGLRQEAEVHRTRIRELETSLEKS 625
Query 897 QKVANTQSFNLMSEAQMKDFEKK-------------FGGLTDRISSLWDKGIQSM 938
+ + TQS L + + + K GL + SLW + +Q++
Sbjct 626 LQESRTQSERLAVHLEAEKSKHKTELTALAEKHRTELEGLQQQQHSLWTERLQNL 680
Score = 37.0 bits (84), Expect = 2e-04
Identities = 33/155 (21%), Positives = 70/155 (45%), Gaps = 10/155 (6%)
Query 760 DLKKALEDIEKAKISDAEKAQLKVKAEKVASDKIKALRAEQFEKIKEIREQEIANAIEQA 819
+L++ E E+A + EKA + + A ++K EQ + ++ E+E +
Sbjct 447 ELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKVEMDEQIKAVERAGEEERLRLQHEL 506
Query 820 QRI----FDIEKASIQAQFDANKISNAQKVQMEKQLEDQLRAIKRNGLEE-RLKLEE--- 871
R+ + K + + + D K+ Q E++L +L + +R E+ R+ LE+
Sbjct 507 SRVRQEAVSMAKKNSEQRADLQKLHAEQLASKEQELSQKLESRERELQEQMRMALEKSRS 566
Query 872 QYSSISGKSGNQSRITNDIANLDTDQKVANTQSFN 906
+Y ++ + Q + + L+ +K T+S N
Sbjct 567 EYLKLTQEKEQQESLA--LEELELQKKAILTESEN 599
Score = 34.7 bits (78), Expect = 8e-04
Identities = 46/224 (21%), Positives = 100/224 (45%), Gaps = 22/224 (10%)
Query 723 KKPKKGKSDAER-EAEREAKAIADIRYKYATEEEKIQLDLKKALEDI--EKAKISDAEKA 779
KK + ++D ++ AE+ A ++ K + E ++Q ++ ALE E K++ ++
Sbjct 518 KKNSEQRADLQKLHAEQLASKEQELSQKLESRERELQEQMRMALEKSRSEYLKLTQEKEQ 577
Query 780 QLKVKAEKVASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKI 839
Q + E++ K KA+ E K++ +R++ + + +EK+ +++ + ++
Sbjct 578 QESLALEELELQK-KAILTESENKLQGLRQEAEVHRTRIRELETSLEKSLQESRTQSERL 636
Query 840 SNAQKVQMEKQLEDQLRAIKRNGLEERLKLEEQYSSISGKSGNQSRITNDIANLDTDQKV 899
+ + + K + +L A+ E L++Q S+ T + NL +
Sbjct 637 AVHLEAEKSKH-KTELTALAEKHRTELEGLQQQQHSL---------WTERLQNLSQQHQA 686
Query 900 ANTQSFNLMSEAQMKDFEKKFGGLTDRISSLWDKGIQSMMNGTL 943
A + E + K ++K L ++ SL+ IQ M TL
Sbjct 687 A-------VEELREKHQQEKDALLKEK-ESLFQAHIQDMNEKTL 722
Score = 33.9 bits (76), Expect = 0.001
Identities = 55/275 (20%), Positives = 122/275 (44%), Gaps = 37/275 (13%)
Query 674 SGASEKGGKKFQLLFLKDPNATDESPKPSPLPTFNPNRGIGT---GKKDEKEKKPKKGKS 730
S E GGK + L+D +E+ K + + +GT G+ + E K +
Sbjct 1917 SPQQEMGGKNTSVEILED--RPEENSKSHVIES-----KLGTPMDGRHSDLESK----LA 1965
Query 731 DAEREAEREAKAIADIR--YKYATEEEKIQLD-LKKALEDIEKAKISDAEKAQLKVKAEK 787
+ERE ++ +K + ++ + +E + +LD L+K E + K+ E+ L++K
Sbjct 1966 GSEREKQKLSKEVGRLQKDLRALRKEHQQELDILRKECEQEAEEKLKQ-EQEDLELKHSS 2024
Query 788 VASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQKVQM 847
++ + +K +E+ E+ + I++AQ ++E +Q+ + + + + +
Sbjct 2025 TLKQLMREFNTQLAQKEQEL-ERTVQETIDKAQ---EVEAELLQSHQEETQQLHRKIAEK 2080
Query 848 EKQLEDQLRAIKR--NGLEERL---------KLEEQYSSISGKSGNQSRITNDIANLDTD 896
E L+ R + + EE + +LEE + + + + L+
Sbjct 2081 EDDLQRTARRYEEILDAREEEMTAKVMDLQTRLEELQKKYEHRLEQEESAKDSVTVLELQ 2140
Query 897 QKVANTQSFNLMSEAQMKDFE--KKFGGLTDRISS 929
++A Q L+S++++K+ E ++ L DR+ S
Sbjct 2141 TQLA--QKTTLISDSKLKEQELREQVHNLEDRLKS 2173
Score = 31.6 bits (70), Expect = 0.007
Identities = 66/315 (21%), Positives = 136/315 (43%), Gaps = 41/315 (13%)
Query 639 QYTNKMKNRANDVKTTWNDAASKAGTSWKTAWENISGASEKGGKKFQLLFLKDPNATDES 698
Q TN+++ + N +KT D ++GG++ Q+ K+ T
Sbjct 1335 QVTNQLEEKENQIKTMKADMEGLIAEK--------EALQQEGGQQQQVASEKESCITQLK 1386
Query 699 PKPSPLPTFNPNRGIGTGKKDEKEKKPK-----KGKSDAEREAER------EAKAIADIR 747
+ S N N + +++ EKK + K SD + E +A+AI+ +
Sbjct 1387 KELSE----NIN-AVTLLREELSEKKSEIASLSKQLSDVSAQLENSISPSDKAEAISALS 1441
Query 748 YKYATEEEKIQLDLKK---ALEDIEKAKISDAEKAQLKVKAEKVASDKIKAL-RAEQFEK 803
++ +E ++Q L++ ++ + K K+S E Q+ + K + K KA R Q++
Sbjct 1442 KQHEEQELQLQAQLRELSSKVDALSKEKMSALE--QVDHWSNKFSEWKKKAQPRFAQYQS 1499
Query 804 -IKEIREQEIANAIEQAQRIFDIE--KASIQAQFDANKISNAQKVQMEKQLEDQL----- 855
IK+++ Q A E ++ I K + Q + + + + E LE +L
Sbjct 1500 TIKDLQTQLDLKAKEAGEKDEQIRLLKEDLDQQNERFESLKGEMEKKECDLETELKTRTA 1559
Query 856 RAIKRNGLEERLKLEEQYSSISGKSGNQSRITNDIANLDTDQKVANTQSFNLMSEAQMKD 915
R ++ + K E + + + ++ +Q R T + T Q++ + + ++++
Sbjct 1560 RVVELEDCITQRKKEVESLNEALRNCSQQRDTEHSGLVQTLQRL---EELGQEKDNKVRE 1616
Query 916 FEKKFGGLTDRISSL 930
E+ GL +R+SSL
Sbjct 1617 AEETVLGLRERVSSL 1631
Score = 29.6 bits (65), Expect = 0.027
Identities = 44/223 (20%), Positives = 95/223 (43%), Gaps = 27/223 (12%)
Query 742 AIADIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQLKVKAEKVASDKIKALRAEQF 801
A++D + ++ EK+++DL AL EK + + E A+LK+ AE+ + LR +
Sbjct 1165 ALSDSHAQLQSQVEKLEVDLGCALN--EKLSLQE-ELAELKMLAER------EKLRVSEL 1215
Query 802 EKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQKVQMEKQLEDQLRAIKRN 861
+ E+E ++ + + ++ + S++ + + + LE+ + R+
Sbjct 1216 TGKVQAAEEE----LQSCKSLHEVSRKSLE----------DKSLNLRTLLEELASQLDRH 1261
Query 862 GLEERLKLEEQYSSISGKSGNQSRITNDIANLDTDQKVANTQSFNLMSE-AQMKDFEKKF 920
+ LE + + + S +++ +A L Q+ T L+ Q+ + E +
Sbjct 1262 CERTKALLEAKTNELVCTSRDKADAI--LARLSRCQRHTATVGEALLRRMGQVSELEAQL 1319
Query 921 GGLTDRISSLWDKGIQSMMNGTLTWQNATNAVMTDMAGYFIQK 963
LT+ +L Q + N +N + DM G +K
Sbjct 1320 TQLTEEQCTL-KNSFQQVTNQLEEKENQIKTMKADMEGLIAEK 1361
Score = 28.9 bits (63), Expect = 0.047
Identities = 37/209 (18%), Positives = 85/209 (41%), Gaps = 15/209 (7%)
Query 729 KSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQLKVKAEKV 788
K A++ + I +R + A E E ++ L E I E+ + K K ++
Sbjct 941 KEQAQQILTEKENVILQMREEQAKEIEILKQKLFSKEESISILH----EEYETKFKNQEK 996
Query 789 ASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQK---- 844
+KIK E E K++ +QE E + ++ + + QF+A + AQ
Sbjct 997 RMEKIKQKAKEMQEMKKKLLDQEAKLKKELENTVLELSQK--EKQFNAKILEMAQANSAG 1054
Query 845 -----VQMEKQLEDQLRAIKRNGLEERLKLEEQYSSISGKSGNQSRITNDIANLDTDQKV 899
++E+ Q+ ++ E L E + + + R ++ + +Q++
Sbjct 1055 ISDTVSRLEENQRQQIESLTGAHQRELDDLIESWEKKLSQQAEELRDQHEKLIEEKEQEL 1114
Query 900 ANTQSFNLMSEAQMKDFEKKFGGLTDRIS 928
+ L +++ ++ ++ LT+ ++
Sbjct 1115 GELKQKVLTVQSEKEEVTQEVARLTEAVT 1143
Score = 27.7 bits (60), Expect = 0.11
Identities = 29/104 (28%), Positives = 50/104 (48%), Gaps = 14/104 (13%)
Query 720 EKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLK------KALEDIEKAKI 773
EK+ K ++ + ER + A++R E + + +K KALED K ++
Sbjct 1609 EKDNKVREAEETVLGLRERVSSLEAELRV-VRKELDDVNSSVKSRDGELKALED--KLEL 1665
Query 774 SDAEKAQLKVKAEKVASDKIKALRAEQFEKIKEIREQEIANAIE 817
A K +LK KAE+ K+ A+R + ++ E + Q+ A E
Sbjct 1666 ESAAKVELKRKAEQ----KLAAIRKQLLSQM-EAKVQQCAKDTE 1704
Score = 26.9 bits (58), Expect = 0.18
Identities = 42/208 (20%), Positives = 93/208 (45%), Gaps = 29/208 (14%)
Query 736 AEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQLKVKAEKVAS----- 790
AERE ++++ K EE++Q K+L ++ + + D + L+ E++AS
Sbjct 1205 AEREKLRVSELTGKVQAAEEELQ--SCKSLHEVSRKSLED-KSLNLRTLLEELASQLDRH 1261
Query 791 -DKIKA-LRAEQFEKIKEIREQ--EIANAIEQAQR---------------IFDIEKASIQ 831
++ KA L A+ E + R++ I + + QR + ++E Q
Sbjct 1262 CERTKALLEAKTNELVCTSRDKADAILARLSRCQRHTATVGEALLRRMGQVSELEAQLTQ 1321
Query 832 AQFDANKISNAQKVQMEKQLEDQLRAIKRNGLEERLKLEEQYSSISGKSGNQSRITNDIA 891
+ + N+ + Q+ QLE++ IK + + E+ ++ + G Q ++ ++
Sbjct 1322 LTEEQCTLKNSFQ-QVTNQLEEKENQIKTMKADMEGLIAEK-EALQQEGGQQQQVASEKE 1379
Query 892 NLDTDQKVANTQSFNLMSEAQMKDFEKK 919
+ T K +++ N ++ + + EKK
Sbjct 1380 SCITQLKKELSENINAVTLLREELSEKK 1407
Score = 22.7 bits (47), Expect = 3.5
Identities = 37/141 (26%), Positives = 61/141 (43%), Gaps = 31/141 (22%)
Query 758 QLDLKKALEDIEKAKISDAEKAQLKVKAEKVASDKIKALRAEQFEKI------KEIREQE 811
Q +L +E EK AE +L+ + EK+ +K + L E +K+ KE QE
Sbjct 1078 QRELDDLIESWEKKLSQQAE--ELRDQHEKLIEEKEQEL-GELKQKVLTVQSEKEEVTQE 1134
Query 812 IANAIEQAQRIFDIEKASIQAQFDANKI-------SNAQ-KVQMEK-------------Q 850
+A E A D+ A +Q Q + S+AQ + Q+EK
Sbjct 1135 VARLTE-AVTGQDVTLAGLQGQLEQKSAAVLALSDSHAQLQSQVEKLEVDLGCALNEKLS 1193
Query 851 LEDQLRAIKRNGLEERLKLEE 871
L+++L +K E+L++ E
Sbjct 1194 LQEELAELKMLAEREKLRVSE 1214
>Q10475 Eukaryotic translation initiation factor 4 gamma [Schizosaccharomyces
pombe (strain 972 / ATCC 24843)]
Length=1403
Score = 52.0 bits (123), Expect = 4e-09
Identities = 58/222 (26%), Positives = 105/222 (47%), Gaps = 13/222 (6%)
Query 717 KKDEKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEE-KIQLDLKKALEDIEKAKISD 775
K+ +EK + + +A+REAE +AK A+ + K EE+ K + + K E E AK
Sbjct 546 KRKAEEKARLEAEENAKREAEEQAKREAEEKAKREAEEKAKREAEEKAKREAEENAKREA 605
Query 776 AEKA--QLKVKAEKVASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQ 833
EKA + + KA++ A +K K E EK K E++ E+ + EKA +A+
Sbjct 606 EEKAKREAEEKAKREAEEKAK---REAEEKAKREAEEKAKREAEEKAKREAEEKAKREAE 662
Query 834 FDANKIS--NAQKVQMEKQLEDQLRAIKRNGLEE-RLKLEEQYSSISGKS---GNQSRIT 887
+A + + A++ E + +KR E + K EE+ + K+ + + +
Sbjct 663 ENAKREAEEKAKREAEENAKREAEEKVKRETEENAKRKAEEEGKREADKNPEIKSSAPLA 722
Query 888 NDIANLDTDQKVANTQSFNLMSEAQMKDFEKKFGGLTDRISS 929
+ AN+DT K N ++ + +++ + G T +SS
Sbjct 723 SSEANVDT-SKQTNATEPEVVDKTKVEKLKASEGKSTSSLSS 763
Score = 41.2 bits (95), Expect = 8e-06
Identities = 53/227 (23%), Positives = 94/227 (41%), Gaps = 21/227 (9%)
Query 692 PNATDESPKPSPLPTFNPNRGIGTGKKDEKEKKPKKG------KSDAEREAEREAKAIAD 745
P SP PS + + E+E +K + + +AE EAK A+
Sbjct 491 PQKNASSPNPSETNSRAETPTAAPPQISEEEASQRKDAIKLAIQQRIQEKAEAEAKRKAE 550
Query 746 IRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQLKVKAEKVASDKIKALRAEQFEKIK 805
+ + EE + K+ E+ K + + K + + KA++ A +K K AE+ K +
Sbjct 551 EKARLEAEE-----NAKREAEEQAKREAEEKAKREAEEKAKREAEEKAKR-EAEENAK-R 603
Query 806 EIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQKVQMEKQLEDQLRAIKRNGLEE 865
E E+ A E+A+R + EKA +A+ A++ EK + KR EE
Sbjct 604 EAEEKAKREAEEKAKREAE-EKAKREAE------EKAKREAEEKAKREAEEKAKREA-EE 655
Query 866 RLKLEEQYSSISGKSGNQSRITNDIANLDTDQKVANTQSFNLMSEAQ 912
+ K E + ++ R + A + ++KV N +A+
Sbjct 656 KAKREAEENAKREAEEKAKREAEENAKREAEEKVKRETEENAKRKAE 702
>Q80UF4 Serologically defined colon cancer antigen 8 homolog [Mus
musculus]
Length=717
Score = 50.1 bits (118), Expect = 1e-08
Identities = 49/213 (23%), Positives = 97/213 (46%), Gaps = 14/213 (7%)
Query 729 KSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIE-KAKISDAEKAQLKVKAEK 787
KS+ ER+ ER K +A + K A E+E I+ ++ + ED E K I A+L+ + EK
Sbjct 369 KSELERQTERLEKELASQQEKRAVEKEMIKKEVAREREDAESKMLILSQNIAKLEAQVEK 428
Query 788 VASDKIKAL-RAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQKVQ 846
V +K A+ E+ + +E ++ + + F + K ++ + K K +
Sbjct 429 VTREKTAAVSHLEEIQNHVASQEMDVTKVCGEMR--FQLNKTKMEKD-EVEKEHREYKAK 485
Query 847 MEKQLEDQLRAIKRNGL---EERLKLEEQYSSISGKSGNQSRITNDIANLDTD------Q 897
K LE +++ I++ L E +E++ + R+T + + +
Sbjct 486 SHKDLEMKVQEIEKLRLELSESEQHVEQEQQKAARARQECLRVTELLGEAERQLHLTRLE 545
Query 898 KVANTQSFNLMSEAQMKDFEKKFGGLTDRISSL 930
K + QSF+ ++AQ +++ LT +I +
Sbjct 546 KDSIQQSFSNEAKAQALQAQQREQELTQKIQQM 578
Score = 35.8 bits (81), Expect = 3e-04
Identities = 28/120 (23%), Positives = 59/120 (49%), Gaps = 19/120 (16%)
Query 717 KKDEKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKA----- 771
+KDE EK+ ++ K+ + ++ E + + I +R + + E+ ++ + +KA ++
Sbjct 471 EKDEVEKEHREYKAKSHKDLEMKVQEIEKLRLELSESEQHVEQEQQKAARARQECLRVTE 530
Query 772 KISDAEKAQLKVKAEKVA-------SDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFD 824
+ +AE+ + EK + K +AL+A+Q REQE+ I+Q + D
Sbjct 531 LLGEAERQLHLTRLEKDSIQQSFSNEAKAQALQAQQ-------REQELTQKIQQMETQHD 583
Score = 28.5 bits (62), Expect = 0.056
Identities = 19/70 (27%), Positives = 32/70 (46%), Gaps = 2/70 (3%)
Query 51 RDSLKNIDVSLNIDMSAVQQRLSSAANTIK--TQINNIVDDASIKLKIDTTSLSSEIEHA 108
RD L ++ VS+ ++ Q+R +SA +K Q+ + K I L SE+E
Sbjct 316 RDDLMSVLVSVRSSLAEAQKRETSAYEQVKHAVQMTEEANFEKTKALIQCEQLKSELERQ 375
Query 109 ENLIRSRLSS 118
+ L+S
Sbjct 376 TERLEKELAS 385
Score = 26.6 bits (57), Expect = 0.22
Identities = 29/121 (24%), Positives = 51/121 (42%), Gaps = 14/121 (12%)
Query 729 KSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQLKVKAEKV 788
+S +RE A +++ EE + KAL E+ K S+ E+ +++ E
Sbjct 327 RSSLAEAQKRETSAYEQVKHAVQMTEEA-NFEKTKALIQCEQLK-SELERQTERLEKELA 384
Query 789 ASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQKVQME 848
+ + +A+ E +K E+A E A+ K I +Q A + +KV E
Sbjct 385 SQQEKRAVEKEMIKK-------EVAREREDAE-----SKMLILSQNIAKLEAQVEKVTRE 432
Query 849 K 849
K
Sbjct 433 K 433
>Q65SK9 Translation initiation factor IF-2 [Mannheimia succiniciproducens
(strain MBEL55E)]
Length=820
Score = 48.5 bits (114), Expect = 4e-08
Identities = 34/117 (29%), Positives = 60/117 (51%), Gaps = 4/117 (3%)
Query 713 IGTGKKDEKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAK 772
+ GK + +K +K ++A ++A EAK A + A E+ + +KA ++ EKA+
Sbjct 25 VAGGKVQVEVRKSRKIDTEAAKKAAEEAKLKAQEAAEKAAAEKAEKEAAEKAKKNAEKAR 84
Query 773 ISDAEKAQLKVKAEKVASDKIKALRAEQFEKIKEI----REQEIANAIEQAQRIFDI 825
++ A K VK D+IKA AE K E+ E++ A E+A+R+ ++
Sbjct 85 VAAAVKKPEPVKVVDAEKDRIKAEEAELRRKADELARQKAEEQARKAAEEAKRLAEL 141
Score = 43.5 bits (101), Expect = 1e-06
Identities = 71/312 (23%), Positives = 130/312 (42%), Gaps = 50/312 (16%)
Query 730 SDAEREAEREAKAIA-DIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQLKVK--AE 786
+D E + E K ++ R K K+Q++++K+ + +A AE+A+LK + AE
Sbjct 2 TDKETQNENAPKKLSLQRRVKTTVAGGKVQVEVRKSRKIDTEAAKKAAEEAKLKAQEAAE 61
Query 787 KVASDKIKALRAEQFEKIKEIREQEIANAIEQAQ--RIFDIEKASIQAQFDANKISNAQK 844
K A++K + AE+ +K E + +A A+++ + ++ D EK I+A+ +A A +
Sbjct 62 KAAAEKAEKEAAEKAKKNAE--KARVAAAVKKPEPVKVVDAEKDRIKAE-EAELRRKADE 118
Query 845 VQMEKQLEDQLRAIKRNGLEERLKLEEQYSSISGKSGNQSRITNDIANLDTDQKVANTQS 904
+ +K E +A + L + + + +S + +T+ A D++ +
Sbjct 119 LARQKAEEQARKAAEEAKRLAELAADRETTEVSDDFSDY-HLTSTYAREAEDEEERRKEG 177
Query 905 FNLMSEAQMKDFEKKFGGLTDRISSLWDKGIQSMMNGTLTWQNATNAVMTDMAGYFIQKM 964
+ K + K GG D NG+ +NA D+ G Q
Sbjct 178 ---RGRGKNKVGKAKKGGRDD--------------NGSKDERNADRRNQKDVKGKGKQ-- 218
Query 965 VTEPLRQYMVGLARRLAVRLGFIKTETAAEVTGQAAQTGAVVAGETTKTMATSTGALARL 1024
G A++ F K A VV GET + ++
Sbjct 219 ----------GKKGSSAIQQAFTKPAQAVNRD--------VVIGETITVAELAN----KM 256
Query 1025 AIKASETIKTIM 1036
A+KA+E IKT+M
Sbjct 257 AVKATEIIKTMM 268
>Q9BV73 Centrosome-associated protein CEP250 [Homo sapiens]
Length=2442
Score = 48.5 bits (114), Expect = 5e-08
Identities = 48/230 (21%), Positives = 103/230 (45%), Gaps = 40/230 (17%)
Query 726 KKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQLKVKA 785
++GK+ E++ K + +R K+ E Q +L KALE +E+ K+ + ++++K
Sbjct 838 QEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKM----ELEMRLKE 893
Query 786 EKVASDKIKALRAE------------QFEKIKE---------IREQEIANAIEQAQRIFD 824
++ + I+A R E Q E KE ++E+A+A +Q +R+
Sbjct 894 QQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQ 953
Query 825 IEKASIQAQFDANKISNAQKVQMEKQLE-------DQLRAIKRNG---LEERLKLEEQYS 874
K + + I Q + +++L+ D L A++ L++++ L++Q
Sbjct 954 DMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVE 1013
Query 875 SISGKSGNQSRITNDIANLDTDQKVANTQSFNLMSEAQMKDFEKKFGGLT 924
+ + Q + + + +K+ TQ +N + K+ E++ LT
Sbjct 1014 DLKSQLVAQDD-SQRLVEQEVQEKLRETQEYNRI----QKELEREKASLT 1058
Score = 38.9 bits (89), Expect = 4e-05
Identities = 41/203 (20%), Positives = 97/203 (48%), Gaps = 22/203 (11%)
Query 721 KEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQ 780
KE++ + A+RE ER A + + TE+E++ L +E + E A
Sbjct 892 KEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSL--------LETLLQTQKELAD 943
Query 781 LKVKAEKVASD-KIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKI 839
+ E++ D K++ L+ ++ I + + QE +++A R + A++Q + +
Sbjct 944 ASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQ---EESSS 1000
Query 840 SNAQKVQMEKQLED---QLRA------IKRNGLEERLKLEEQYSSISGKSGNQSRITNDI 890
K+ ++KQ+ED QL A + ++E+L+ ++Y+ I K + + + +
Sbjct 1001 LLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQ-KELEREKASLTL 1059
Query 891 ANLDTDQKVANTQSFNLMSEAQM 913
+ ++ +Q++ Q + + + ++
Sbjct 1060 SLMEKEQRLLVLQEADSIRQQEL 1082
Score = 36.2 bits (82), Expect = 3e-04
Identities = 45/235 (19%), Positives = 103/235 (44%), Gaps = 32/235 (14%)
Query 717 KKDEKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDA 776
K+ E K + D++R E+E + + + E +IQ +L++ + + +
Sbjct 1010 KQVEDLKSQLVAQDDSQRLVEQEVQE----KLRETQEYNRIQKELEREKASLTLSLMEKE 1065
Query 777 EKAQLKVKAEKVASDKIKALRAEQFEKIKEIRE-----QEIANAIEQAQRIFDIEKASIQ 831
++ + +A+ + ++ ALR + E E +E + + +++ + F ++A +
Sbjct 1066 QRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLL 1125
Query 832 AQFDANKISNAQKVQMEKQLEDQLRAIKRNGLEERLKLEEQYSSISG-----KSGNQSRI 886
+ +A+ I+ E+QL L A + + +L+L S + + GNQ++
Sbjct 1126 EELEASHIT-------EQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQA 1178
Query 887 TNDIANLDTDQKVANTQSFNLMSEAQMKDFEKKFGGLTDRISSLWDKGIQSMMNG 941
+A+L + A Q+ + E++ + G D S+W G++ NG
Sbjct 1179 QAQLASLYS----ALQQALGSVCESR-----PELSGGGDSAPSVW--GLEPDQNG 1222
Score = 32.7 bits (73), Expect = 0.003
Identities = 47/206 (23%), Positives = 92/206 (45%), Gaps = 17/206 (8%)
Query 717 KKDEKEKKPKKGKSDAEREAEREAKAIAD-IRYKYATEEEKIQLDLKKALEDIEKAKISD 775
K+ ++E + + +S + R E A+A A+ ++ +Q + LE E ++ +
Sbjct 1936 KERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLE 1995
Query 776 AEKAQLKVKAEKVASDKIK---ALRAEQFE-KIKEIREQEIANAIEQAQRIFDIEKASIQ 831
A A L+ + + + ALR ++ E + +++R QE ++QA D E Q
Sbjct 1996 ASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQ 2055
Query 832 AQFDANKISNAQKVQ----MEKQ------LEDQLRAIKRNGLEERLKLEEQYSSISGKSG 881
+ + S AQ+VQ EKQ E+++R + ++ E +L L ++ I
Sbjct 2056 EREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRE 2115
Query 882 NQSRITNDIANLDTDQKVANTQSFNL 907
Q R N++ L K + + +L
Sbjct 2116 TQQR--NNLEALPHSHKTSPMEEQSL 2139
Score = 29.3 bits (64), Expect = 0.036
Identities = 32/152 (21%), Positives = 65/152 (43%), Gaps = 19/152 (13%)
Query 72 LSSAANTIKTQINNIVDDASIKLK-------IDTTSLSS---EIEHAENLIRSRLSSLPI 121
LSS+ NT+KT++ ++ A++KL +D L+ ++E + SR+ +
Sbjct 580 LSSSENTLKTEVADL-RAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQ 638
Query 122 QNVKLDIDIHEIQRRLNLITGQQVKIKLGLDT-----STLQAQL---HQAKNTITTMLQS 173
L +D+ E ++R + + ++ L + LQA L + K I L
Sbjct 639 ARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSE 698
Query 174 TLSSAIRITVNLPLLAAQLSQAKAMINRALSQ 205
+ T L L + + + ++ RA+ +
Sbjct 699 SRHQQEAATTQLEQLHQEAKRQEEVLARAVQE 730
Score = 28.9 bits (63), Expect = 0.047
Identities = 41/195 (21%), Positives = 80/195 (41%), Gaps = 19/195 (10%)
Query 732 AEREAEREA-----KAIADIRYKYATEEEKIQLDLKKALE--DIEKAKISDAEKAQLKVK 784
AERE E E + + R E + LDLKK + D+++ +I + EK + ++
Sbjct 1431 AEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLE 1490
Query 785 AEKVASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQK 844
+A + + Q E+I+E+ + ++ ++EK + ++ +
Sbjct 1491 HLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQD--- 1547
Query 845 VQMEKQLEDQLRAIKRNGLEERLKLEEQYSSISGKSGNQ--SRITNDIANLDTDQKVANT 902
++KQL L + E K+E Q I G + R+ LD +++
Sbjct 1548 --LKKQLV-TLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQEL 1604
Query 903 QSFNLMSEAQMKDFE 917
Q+ +Q+ D E
Sbjct 1605 QA----QSSQIHDLE 1615
Score = 28.1 bits (61), Expect = 0.081
Identities = 28/172 (16%), Positives = 79/172 (46%), Gaps = 16/172 (9%)
Query 727 KGKSDAEREAEREAKAI-------ADIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKA 779
KG S A+R + K I + + ++ E ++++ L++ L+ + + K+ +
Sbjct 1714 KGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHR-KVGETSLL 1772
Query 780 QLKVKAEKVASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKI 839
+ + E V + + ++ + E++EQ + + +++AQR A + +A +
Sbjct 1773 LSQREQEIVVLQQ----QLQEAREQGELKEQSLQSQLDEAQRAL----AQRDQELEALQQ 1824
Query 840 SNAQKVQMEKQLEDQLRAIKRNGLEERLKLEEQYSSISGKSGNQSRITNDIA 891
Q E++++++ A++ + + L+E++ + R+ ++A
Sbjct 1825 EQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELA 1876
Score = 26.9 bits (58), Expect = 0.18
Identities = 33/167 (20%), Positives = 74/167 (44%), Gaps = 20/167 (12%)
Query 717 KKDEKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQL-------DLKKALEDIE 769
++D++ K ++ + +R+ E + + + ++E+IQ+ K ED+E
Sbjct 1627 ERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLE 1686
Query 770 KAKISDAEKAQLKVKAEKVASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKAS 829
+ K+S E+ + E ++ RAE+ + + + ++E + I ++
Sbjct 1687 QIKLSLRERGR-----ELTTQRQLMQERAEEGKGPSKAQR----GSLEHMKLILRDKEKE 1737
Query 830 IQAQFDANKISNAQKVQMEKQLEDQLRAIKRNGLEERLKLEEQYSSI 876
++ Q I Q +++ QLE QL+ + R E L L ++ I
Sbjct 1738 VECQ--QEHIHELQ--ELKDQLEQQLQGLHRKVGETSLLLSQREQEI 1780
Score = 26.6 bits (57), Expect = 0.24
Identities = 24/113 (21%), Positives = 52/113 (46%), Gaps = 6/113 (5%)
Query 818 QAQRIFDIEKASIQAQFDANKISNAQKVQMEKQLEDQLRAIKRNGLEERLKLEEQYSSIS 877
+ Q+ D+ + +Q + + A+K Q+ +L+D R + +N EE+ K E + +S+
Sbjct 1254 KTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQN-QEEKSKWEGKQNSLE 1312
Query 878 GKSGNQSRITNDIANLDTDQKVANTQSFNLMSEAQMKDFEKKFGGLTDRISSL 930
+ + +A+L + + A Q E ++ K+ LT ++ L
Sbjct 1313 SE---LMELHETMASLQSRLRRAELQRMEAQGERELLQAAKE--NLTAQVEHL 1360
Score = 26.2 bits (56), Expect = 0.31
Identities = 38/175 (22%), Positives = 65/175 (37%), Gaps = 48/175 (27%)
Query 797 RAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQKVQMEKQLEDQLR 856
+ ++ EK R QE+ Q D+EKA +Q D +A Q +KQ ED +
Sbjct 252 KTQELEKEAHERSQELIQLKSQG----DLEKAELQ---DRVTELSALLTQSQKQNEDYEK 304
Query 857 AIK------------------------RNGLEERLKLE-----------EQYSSISGKSG 881
IK RN EE+L L+ E+ +I+ SG
Sbjct 305 MIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSG 364
Query 882 NQ------SRITNDIANLDTDQKVANTQSFNLMSEAQMKDFEKKFGGLTDRISSL 930
++ S I + D D+ + +S ++D ++ G + ++ L
Sbjct 365 HENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLL 419
Score = 24.6 bits (52), Expect = 0.91
Identities = 17/62 (27%), Positives = 29/62 (47%), Gaps = 7/62 (11%)
Query 105 IEHAENLIRSRLSSLPIQNV-------KLDIDIHEIQRRLNLITGQQVKIKLGLDTSTLQ 157
+ A+ L+ S L QN +L++ I + + +I G+ +KL LDT Q
Sbjct 762 LSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQ 821
Query 158 AQ 159
A+
Sbjct 822 AE 823
>P61584 Rho-associated protein kinase 1 [Pan troglodytes]
Length=1003
Score = 47.8 bits (112), Expect = 8e-08
Identities = 46/217 (21%), Positives = 90/217 (41%), Gaps = 20/217 (9%)
Query 3 NQNEVEVKITASTDSLSEGMNQATNNVQSAANDINRIADSIKTAFDGVRDSLKNIDVSLN 62
+ +E+ + A SL E + +N++ + D + + N+++ LN
Sbjct 268 HDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHS----EKEKNNLEIDLN 323
Query 63 IDMSAVQQRLSSAANTIK------TQINNIVDDASIKLKIDTTSLSSEIEHAENLIRSRL 116
+ ++QQRL N K T + +++A + E A +R+
Sbjct 324 YKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRV 383
Query 117 SSLPIQNVKLDIDIHEIQRRLNLITGQQVKIKLGLDTSTLQAQLHQAKNTITTMLQSTLS 176
+ Q LD+D+ + Q++L +TG + +++ + TLQ + K +LQ+ L
Sbjct 384 VQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKR---LLLQNELK 440
Query 177 SAIRITVNLPLLAAQLSQ-------AKAMINRALSQL 206
+ NL L Q+ Q AK ++ L+QL
Sbjct 441 TQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQL 477
Score = 35.4 bits (80), Expect = 4e-04
Identities = 44/224 (20%), Positives = 98/224 (44%), Gaps = 45/224 (20%)
Query 717 KKDEKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEK-------------------I 757
+++ E K K + + ++ EAK++A + +EE+ +
Sbjct 334 EQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSML 393
Query 758 QLDLKKALEDIE-----KAKISDAEKAQLKVKAEKVASD--------KIKALRAEQFEKI 804
+DLK++ + +E K ++ D E L ++ E+ ++ K +A A+ + +
Sbjct 394 DVDLKQSQQKLEHLTGNKERMED-EVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGL 452
Query 805 KEIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQKVQMEKQLEDQLRAIKRNGLE 864
++ +QEI N + +A+R+ + E A + Q+ N+ ++L+DQL A +
Sbjct 453 EKQMKQEI-NTLLEAKRLLEFELAQLTKQYRGNE-------GQMRELQDQLEAEQYFSTL 504
Query 865 ERLKLEEQYSSISGKSGNQ----SRITNDIANLDTDQKVANTQS 904
+ +++E I K+ + N+ L T +A T++
Sbjct 505 YKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKA 548
Score = 34.7 bits (78), Expect = 8e-04
Identities = 52/241 (22%), Positives = 102/241 (42%), Gaps = 20/241 (8%)
Query 704 LPTFNPNRGIGTGKKDEK-EKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLK 762
L + NPN + D+ ++ +K E + E + ++ K T K+ +K
Sbjct 55 LSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMK 114
Query 763 KALEDIEKAKISDAEKAQLKVKAEKVASDKIKAL--RAEQFEKIKEIREQEIANAIEQAQ 820
+ E+ + + ++ +Q++ K + + +I +AEQ + + E E++ +Q +
Sbjct 115 ELDEEGNQRRNLESTVSQIE-KEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLE 173
Query 821 RIFDIEKASIQAQFDANKISNAQKVQMEKQLE---DQLRAIKRNGLEERLKLEEQYSSIS 877
D++K S +Q K+S Q++KQLE D LR + R E SIS
Sbjct 174 ---DLKKVSQNSQLANEKLS-----QLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSIS 225
Query 878 GKSGNQSRITNDIANLDTDQKVANTQSFNLMS--EAQMKD---FEKKFGGLTDRISSLWD 932
+ L+ + + + L + EA+ +D + G L RI+SL +
Sbjct 226 QLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQE 285
Query 933 K 933
+
Sbjct 286 E 286
Score = 33.1 bits (74), Expect = 0.002
Identities = 44/200 (22%), Positives = 87/200 (44%), Gaps = 33/200 (17%)
Query 27 NNVQSAANDINRIADSIKTAFDGVRDSLKNID-VSLNIDM-----SAVQQRLSSAANTIK 80
N Q A N +++ ++D L+++ VS N + S +Q++L A + ++
Sbjct 145 NEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLR 204
Query 81 TQINNIVDDASIKLKIDTTSLSSEIEHAENL---IRSRLSSLPIQNVKLDIDIHEIQRRL 137
T+ D +++L+ T +S I E+L ++ R L + D D +++Q L
Sbjct 205 TE-----SDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAIL 259
Query 138 NLITGQQVKIKLGLDTST---LQAQLHQAKNTITTMLQSTLSSAIRITVNLPLLAAQLSQ 194
+ + G D+ LQA++ T LQ + + NL + + +
Sbjct 260 -----EAERRDRGHDSEMIGDLQARI--------TSLQEEVK---HLKHNLEKVEGERKE 303
Query 195 AKAMINRALSQLNGSNINLN 214
A+ M+N + + N I+LN
Sbjct 304 AQDMLNHSEKEKNNLEIDLN 323
Score = 30.4 bits (67), Expect = 0.015
Identities = 41/215 (19%), Positives = 92/215 (43%), Gaps = 23/215 (11%)
Query 730 SDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQLKVKAEKVA 789
++ + E+E+ A+ + + +Y T+E K K A + ++ D ++L+ +A +
Sbjct 544 AETKAESEQLARGLLEEQYFELTQESK-----KAASRNRQEITDKDHTVSRLE-EANSML 597
Query 790 SDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQ------ 843
+ I+ LR E E +++++ E +E+ + I ++ KA+ + + + Q
Sbjct 598 TKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNL-KAAFEKNINTERTLKTQAVNKLA 656
Query 844 --------KVQMEKQLEDQLRAIKRNGLEERLKLEEQYSSISGKSGNQSRITNDI-ANLD 894
K+ +K LR ++ + +L+L ++ + + ND+ A L
Sbjct 657 EIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLV 716
Query 895 TDQKVANTQSFNLMS-EAQMKDFEKKFGGLTDRIS 928
+ N L S E+ ++ K L+D S
Sbjct 717 EECAHRNELQMQLASKESDIEQLRAKLLDLSDSTS 751
>Q13464 Rho-associated protein kinase 1 [Homo sapiens]
Length=1354
Score = 47.8 bits (112), Expect = 8e-08
Identities = 46/217 (21%), Positives = 90/217 (41%), Gaps = 20/217 (9%)
Query 3 NQNEVEVKITASTDSLSEGMNQATNNVQSAANDINRIADSIKTAFDGVRDSLKNIDVSLN 62
+ +E+ + A SL E + +N++ + D + + N+++ LN
Sbjct 619 HDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHS----EKEKNNLEIDLN 674
Query 63 IDMSAVQQRLSSAANTIK------TQINNIVDDASIKLKIDTTSLSSEIEHAENLIRSRL 116
+ ++QQRL N K T + +++A + E A +R+
Sbjct 675 YKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRV 734
Query 117 SSLPIQNVKLDIDIHEIQRRLNLITGQQVKIKLGLDTSTLQAQLHQAKNTITTMLQSTLS 176
+ Q LD+D+ + Q++L +TG + +++ + TLQ + K +LQ+ L
Sbjct 735 VQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKR---LLLQNELK 791
Query 177 SAIRITVNLPLLAAQLSQ-------AKAMINRALSQL 206
+ NL L Q+ Q AK ++ L+QL
Sbjct 792 TQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQL 828
Score = 35.4 bits (80), Expect = 5e-04
Identities = 44/224 (20%), Positives = 98/224 (44%), Gaps = 45/224 (20%)
Query 717 KKDEKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEK-------------------I 757
+++ E K K + + ++ EAK++A + +EE+ +
Sbjct 685 EQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSML 744
Query 758 QLDLKKALEDIE-----KAKISDAEKAQLKVKAEKVASD--------KIKALRAEQFEKI 804
+DLK++ + +E K ++ D E L ++ E+ ++ K +A A+ + +
Sbjct 745 DVDLKQSQQKLEHLTGNKERMED-EVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGL 803
Query 805 KEIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQKVQMEKQLEDQLRAIKRNGLE 864
++ +QEI N + +A+R+ + E A + Q+ N+ ++L+DQL A +
Sbjct 804 EKQMKQEI-NTLLEAKRLLEFELAQLTKQYRGNE-------GQMRELQDQLEAEQYFSTL 855
Query 865 ERLKLEEQYSSISGKSGNQ----SRITNDIANLDTDQKVANTQS 904
+ +++E I K+ + N+ L T +A T++
Sbjct 856 YKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKA 899
Score = 34.7 bits (78), Expect = 8e-04
Identities = 52/241 (22%), Positives = 102/241 (42%), Gaps = 20/241 (8%)
Query 704 LPTFNPNRGIGTGKKDEK-EKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLK 762
L + NPN + D+ ++ +K E + E + ++ K T K+ +K
Sbjct 406 LSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMK 465
Query 763 KALEDIEKAKISDAEKAQLKVKAEKVASDKIKAL--RAEQFEKIKEIREQEIANAIEQAQ 820
+ E+ + + ++ +Q++ K + + +I +AEQ + + E E++ +Q +
Sbjct 466 ELDEEGNQRRNLESTVSQIE-KEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLE 524
Query 821 RIFDIEKASIQAQFDANKISNAQKVQMEKQLE---DQLRAIKRNGLEERLKLEEQYSSIS 877
D++K S +Q K+S Q++KQLE D LR + R E SIS
Sbjct 525 ---DLKKVSQNSQLANEKLS-----QLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSIS 576
Query 878 GKSGNQSRITNDIANLDTDQKVANTQSFNLMS--EAQMKD---FEKKFGGLTDRISSLWD 932
+ L+ + + + L + EA+ +D + G L RI+SL +
Sbjct 577 QLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQE 636
Query 933 K 933
+
Sbjct 637 E 637
Score = 33.1 bits (74), Expect = 0.002
Identities = 44/200 (22%), Positives = 87/200 (44%), Gaps = 33/200 (17%)
Query 27 NNVQSAANDINRIADSIKTAFDGVRDSLKNID-VSLNIDM-----SAVQQRLSSAANTIK 80
N Q A N +++ ++D L+++ VS N + S +Q++L A + ++
Sbjct 496 NEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLR 555
Query 81 TQINNIVDDASIKLKIDTTSLSSEIEHAENL---IRSRLSSLPIQNVKLDIDIHEIQRRL 137
T+ D +++L+ T +S I E+L ++ R L + D D +++Q L
Sbjct 556 TE-----SDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAIL 610
Query 138 NLITGQQVKIKLGLDTST---LQAQLHQAKNTITTMLQSTLSSAIRITVNLPLLAAQLSQ 194
+ + G D+ LQA++ T LQ + + NL + + +
Sbjct 611 -----EAERRDRGHDSEMIGDLQARI--------TSLQEEVK---HLKHNLEKVEGERKE 654
Query 195 AKAMINRALSQLNGSNINLN 214
A+ M+N + + N I+LN
Sbjct 655 AQDMLNHSEKEKNNLEIDLN 674
Score = 30.4 bits (67), Expect = 0.015
Identities = 41/215 (19%), Positives = 92/215 (43%), Gaps = 23/215 (11%)
Query 730 SDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQLKVKAEKVA 789
++ + E+E+ A+ + + +Y T+E K K A + ++ D ++L+ +A +
Sbjct 895 AETKAESEQLARGLLEEQYFELTQESK-----KAASRNRQEITDKDHTVSRLE-EANSML 948
Query 790 SDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQ------ 843
+ I+ LR E E +++++ E +E+ + I ++ KA+ + + + Q
Sbjct 949 TKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNL-KAAFEKNINTERTLKTQAVNKLA 1007
Query 844 --------KVQMEKQLEDQLRAIKRNGLEERLKLEEQYSSISGKSGNQSRITNDI-ANLD 894
K+ +K LR ++ + +L+L ++ + + ND+ A L
Sbjct 1008 EIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLV 1067
Query 895 TDQKVANTQSFNLMS-EAQMKDFEKKFGGLTDRIS 928
+ N L S E+ ++ K L+D S
Sbjct 1068 EECAHRNELQMQLASKESDIEQLRAKLLDLSDSTS 1102
>O75962 Triple functional domain protein [Homo sapiens]
Length=3097
Score = 45.4 bits (106), Expect = 4e-07
Identities = 26/81 (32%), Positives = 41/81 (51%), Gaps = 1/81 (1%)
Query 184 NLPLLAAQLSQAKAMINRALSQLNGSNINLNTVINIDATSTMLRSSLDRLKTSVDHLRNR 243
N P A S+ ++ + + ++ + I+ R+ L+ L + +++ RN
Sbjct 2231 NDPCKFALTSRTGDVVETFILHSSSPSVRQTWIHEINQILENQRNFLNALTSPIEYQRNH 2290
Query 244 LGSGGGGG-GGSGSGGGSGSG 263
G GGGGG GGSG GGGSG G
Sbjct 2291 SGGGGGGGSGGSGGGGGSGGG 2311
Score = 26.6 bits (57), Expect = 0.24
Identities = 13/20 (65%), Positives = 13/20 (65%), Gaps = 2/20 (10%)
Query 245 GSGGGG--GGGSGSGGGSGS 262
GSGGGG GGSG GG S
Sbjct 2307 GSGGGGAPSGGSGHSGGPSS 2326
Score = 25.0 bits (53), Expect = 0.70
Identities = 16/47 (34%), Positives = 23/47 (49%), Gaps = 7/47 (15%)
Query 1096 TQLHEEEMVLPKQHANTIRALG------KSMANGGVGGDAAASGDGG 1136
T +HE +L Q N + AL ++ + GG GG + SG GG
Sbjct 2261 TWIHEINQILENQR-NFLNALTSPIEYQRNHSGGGGGGGSGGSGGGG 2306
Score = 22.7 bits (47), Expect = 3.5
Identities = 8/18 (44%), Positives = 10/18 (56%), Gaps = 0/18 (0%)
Query 246 SGGGGGGGSGSGGGSGSG 263
+ GSG GGG+G G
Sbjct 18 AAAASAAGSGCGGGAGEG 35
Score = 21.6 bits (44), Expect = 7.9
Identities = 10/25 (40%), Positives = 14/25 (56%), Gaps = 0/25 (0%)
Query 254 SGSGGGSGSGVGTSFLGNFLANIGS 278
+GSG G G+G G LA+I +
Sbjct 24 AGSGCGGGAGEGAEEAAKDLADIAA 48
Score = 21.6 bits (44), Expect = 7.9
Identities = 8/12 (67%), Positives = 9/12 (75%), Gaps = 0/12 (0%)
Query 245 GSGGGGGGGSGS 256
GSG GGG G G+
Sbjct 25 GSGCGGGAGEGA 36
Score = 21.6 bits (44), Expect = 7.9
Identities = 10/20 (50%), Positives = 10/20 (50%), Gaps = 0/20 (0%)
Query 1117 GKSMANGGVGGDAAASGDGG 1136
G S GG GG A SG G
Sbjct 2300 GGSGGGGGSGGGGAPSGGSG 2319
>A8FYS0 Translation initiation factor IF-2 [Shewanella sediminis
(strain HAW-EB3)]
Length=896
Score = 43.5 bits (101), Expect = 1e-06
Identities = 47/197 (24%), Positives = 94/197 (48%), Gaps = 18/197 (9%)
Query 724 KPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDAE-----K 778
K + G A + + K+++ + + + ++++++K +++ +DAE K
Sbjct 50 KKQHGGESAPTKMTLQRKSVSTLSVGSGSASKDVKVEVRKKRTFVKRDPAADAEAEAAAK 109
Query 779 AQLKVKAEKVASDKIKA---LRAEQFEKIK---EIREQEIANAIEQAQRIFDIEKASIQA 832
A+ +VKA + A+ K KA +A+ K K E +E+ A+A E+A+ + + A
Sbjct 110 AEAEVKAAEEAASKAKADAEAKAKAEAKAKADAEAKEKAKASAAEKAKPV-AVTAEEKAA 168
Query 833 QFDANKISNAQKVQMEKQLEDQLRA---IKRNGLEE---RLKLEEQYSSISGKSGNQSRI 886
Q +A+K+ A+ + + +++ +A I R EE R EE+ S K+G+
Sbjct 169 QDEADKLQAAKDTAAKAKADEEAKAAAEIARKLAEENSARWAEEEKQRKESEKTGDHHVT 228
Query 887 TNDIANLDTDQKVANTQ 903
T+ A D AN +
Sbjct 229 TSTEARAAEDTADANAE 245
Score = 40.8 bits (94), Expect = 1e-05
Identities = 37/109 (34%), Positives = 52/109 (48%), Gaps = 21/109 (19%)
Query 722 EKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQ- 780
E+ K K+DAE +A+ EAKA AD K EKAK S AEKA+
Sbjct 118 EEAASKAKADAEAKAKAEAKAKADAEAK-------------------EKAKASAAEKAKP 158
Query 781 LKVKA-EKVASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKA 828
+ V A EK A D+ L+A + K ++E A E A+++ + A
Sbjct 159 VAVTAEEKAAQDEADKLQAAKDTAAKAKADEEAKAAAEIARKLAEENSA 207
Score = 33.5 bits (75), Expect = 0.002
Identities = 29/92 (32%), Positives = 45/92 (49%), Gaps = 6/92 (7%)
Query 719 DEKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLD----LKKALEDIEKAKIS 774
+ K K K K+DAE + + +A A + T EEK D L+ A + KAK
Sbjct 129 EAKAKAEAKAKADAEAKEKAKASAAEKAKPVAVTAEEKAAQDEADKLQAAKDTAAKAKAD 188
Query 775 DAEKAQLKVKAEKVASDKIKALRAEQFEKIKE 806
+ KA ++ A K+A + A AE+ ++ KE
Sbjct 189 EEAKAAAEI-ARKLAEEN-SARWAEEEKQRKE 218
Score = 29.6 bits (65), Expect = 0.026
Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 3/117 (3%)
Query 657 DAASKAGTSWKTAWENISGASEKGGKKFQLLFLKDPNA-TDESPKPSPLPTFNPNRGIGT 715
+AA+KA K A E S A K + +A E K S P
Sbjct 105 EAAAKAEAEVKAAEEAASKAKADAEAKAKAEAKAKADAEAKEKAKASAAEKAKPVAVTAE 164
Query 716 GK--KDEKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEK 770
K +DE +K + A+ +A+ EAKA A+I K A E + +K ++ EK
Sbjct 165 EKAAQDEADKLQAAKDTAAKAKADEEAKAAAEIARKLAEENSARWAEEEKQRKESEK 221
>P0CP34 Stress response protein NST1 [Cryptococcus neoformans
var. neoformans serotype D (strain JEC21 / ATCC MYA-565)]
Length=1353
Score = 43.5 bits (101), Expect = 2e-06
Identities = 36/169 (21%), Positives = 86/169 (51%), Gaps = 14/169 (8%)
Query 717 KKDEKEKKPKKGKSD--AEREAEREAKAIADIRYKYAT-------EEEKIQLD-LKKALE 766
KKD+K+ + +K + + A A E K A +R + A +EE+++ + +K+A +
Sbjct 751 KKDKKKAQKQKAEEERLAREAALEEEKRQAKLRKEEAERERMRRQDEERVRREAVKRAAQ 810
Query 767 DIEKAKISDAEKAQLKVKAEKVASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIE 826
+ + + + ++ Q + K + + K K R E+ +K +E RE E+ + + I +
Sbjct 811 EEAQRQALERKRRQQEEKEREEEAAKKKREREEKAKKEREARENELKEKERKEREIKAAK 870
Query 827 KASIQAQFDANKISNAQKVQMEKQLEDQLRAIKRNGLE----ERLKLEE 871
+ + + + + A++ ++ K+ +++ I++ LE E+++ EE
Sbjct 871 EKAEKERIAKETLEKAERDRLAKEAKEKAEKIRQERLEASRMEKVRKEE 919
Score = 34.3 bits (77), Expect = 0.001
Identities = 42/175 (24%), Positives = 74/175 (42%), Gaps = 23/175 (13%)
Query 719 DEKEKKPKKGKSDAEREAER----------EAKAIADIRYKYATEEEKIQLDLKKALEDI 768
DE +P K AE E +R E + + R + A + E+ L + ED
Sbjct 678 DESRDEPMTEKERAE-EGKRMFQIFAARMFEQRVLQAYRERVAKQREEQLLRELEEEEDS 736
Query 769 EKAK----ISDAEKAQLKVKAEKVASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFD 824
++AK +A+K + K KA+K +++ + R E+ K + A + R D
Sbjct 737 KRAKEEKKAKEAQKKKDKKKAQKQKAEEERLAREAALEEEKRQAKLRKEEAERERMRRQD 796
Query 825 IE-------KASIQAQFDANKISNAQKVQMEKQLEDQLRAIKRNGLEERLKLEEQ 872
E K + Q + + ++ Q EK+ E++ A K+ EE+ K E +
Sbjct 797 EERVRREAVKRAAQEEAQRQALERKRRQQEEKEREEE-AAKKKREREEKAKKERE 850
Score = 24.3 bits (51), Expect = 1.2
Identities = 20/54 (37%), Positives = 28/54 (52%), Gaps = 3/54 (6%)
Query 722 EKKPKKGKSDAEREAEREAKAIA--DIRYKYATEEEKIQLDLKKALEDIEKAKI 773
EK K+ + EREA +AK IA + + A + EK D K A E I A++
Sbjct 913 EKVRKEEAARKEREAVEQAKIIAAQQAQRERAAKAEKNTAD-KAAAERISAARV 965
Score = 23.1 bits (48), Expect = 2.6
Identities = 13/33 (39%), Positives = 17/33 (52%), Gaps = 6/33 (18%)
Query 244 LGSGGGGGG------GSGSGGGSGSGVGTSFLG 270
+GS GG G G G GG +GSG+ +G
Sbjct 1289 IGSSFGGVGAVGSVIGGGMGGTAGSGLVQGHVG 1321
>P0CP35 Stress response protein NST1 [Cryptococcus neoformans
var. neoformans serotype D (strain B-3501A)]
Length=1353
Score = 43.5 bits (101), Expect = 2e-06
Identities = 36/169 (21%), Positives = 86/169 (51%), Gaps = 14/169 (8%)
Query 717 KKDEKEKKPKKGKSD--AEREAEREAKAIADIRYKYAT-------EEEKIQLD-LKKALE 766
KKD+K+ + +K + + A A E K A +R + A +EE+++ + +K+A +
Sbjct 751 KKDKKKAQKQKAEEERLAREAALEEEKRQAKLRKEEAERERMRRQDEERVRREAVKRAAQ 810
Query 767 DIEKAKISDAEKAQLKVKAEKVASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIE 826
+ + + + ++ Q + K + + K K R E+ +K +E RE E+ + + I +
Sbjct 811 EEAQRQALERKRRQQEEKEREEEAAKKKREREEKAKKEREARENELKEKERKEREIKAAK 870
Query 827 KASIQAQFDANKISNAQKVQMEKQLEDQLRAIKRNGLE----ERLKLEE 871
+ + + + + A++ ++ K+ +++ I++ LE E+++ EE
Sbjct 871 EKAEKERIAKETLEKAERDRLAKEAKEKAEKIRQERLEASRMEKVRKEE 919
Score = 34.3 bits (77), Expect = 0.001
Identities = 42/175 (24%), Positives = 74/175 (42%), Gaps = 23/175 (13%)
Query 719 DEKEKKPKKGKSDAEREAER----------EAKAIADIRYKYATEEEKIQLDLKKALEDI 768
DE +P K AE E +R E + + R + A + E+ L + ED
Sbjct 678 DESRDEPMTEKERAE-EGKRMFQIFAARMFEQRVLQAYRERVAKQREEQLLRELEEEEDS 736
Query 769 EKAK----ISDAEKAQLKVKAEKVASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFD 824
++AK +A+K + K KA+K +++ + R E+ K + A + R D
Sbjct 737 KRAKEEKKAKEAQKKKDKKKAQKQKAEEERLAREAALEEEKRQAKLRKEEAERERMRRQD 796
Query 825 IE-------KASIQAQFDANKISNAQKVQMEKQLEDQLRAIKRNGLEERLKLEEQ 872
E K + Q + + ++ Q EK+ E++ A K+ EE+ K E +
Sbjct 797 EERVRREAVKRAAQEEAQRQALERKRRQQEEKEREEE-AAKKKREREEKAKKERE 850
Score = 24.3 bits (51), Expect = 1.2
Identities = 20/54 (37%), Positives = 28/54 (52%), Gaps = 3/54 (6%)
Query 722 EKKPKKGKSDAEREAEREAKAIA--DIRYKYATEEEKIQLDLKKALEDIEKAKI 773
EK K+ + EREA +AK IA + + A + EK D K A E I A++
Sbjct 913 EKVRKEEAARKEREAVEQAKIIAAQQAQRERAAKAEKNTAD-KAAAERISAARV 965
Score = 23.1 bits (48), Expect = 2.6
Identities = 13/33 (39%), Positives = 17/33 (52%), Gaps = 6/33 (18%)
Query 244 LGSGGGGGG------GSGSGGGSGSGVGTSFLG 270
+GS GG G G G GG +GSG+ +G
Sbjct 1289 IGSSFGGVGAVGSVIGGGMGGTAGSGLVQGHVG 1321
>O88735 Ensconsin [Mus musculus]
Length=730
Score = 40.0 bits (92), Expect = 2e-05
Identities = 44/203 (22%), Positives = 94/203 (46%), Gaps = 40/203 (20%)
Query 694 ATDESPKPSPLPTFN----PNRGIGTGKKDE---------------KEKKPKKGKSDAER 734
ATD +P P+P T P GT +E +EK+ ++ K E
Sbjct 431 ATDPAPVPAPSSTVTVGVVPKTSAGTTDPEEATRLLAEKRRLAREQREKEERERKEKEEL 490
Query 735 EAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQLKVKAEKVASDKIK 794
E ++ I ++ + A E + + + ++ E E+A+ EK +L A ++A ++ +
Sbjct 491 ERQK----IEELARRVAEERSRREEEARRLEE--EQAR----EKEEL---ALRLAEEERE 537
Query 795 ALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQKVQMEKQLEDQ 854
E+ E++++ +E+E A A E+A+R + Q + ++++ +K+LE+
Sbjct 538 RWEREEVERVQKQKEEE-ARAREEAERARQEREKHFQKE-------EQERLERKKRLEEI 589
Query 855 LRAIKRNGLEERLKLEEQYSSIS 877
+R +R ++ E++ I+
Sbjct 590 MRRTRRTETADKKTTEQRNGDIA 612
Score = 26.9 bits (58), Expect = 0.17
Identities = 22/98 (22%), Positives = 46/98 (47%), Gaps = 11/98 (11%)
Query 693 NATDESPKPSPLPTFNPNRGIGTGKKDEKEKKPKKGKSDAEREA---EREAKAIADIRYK 749
N + P P P+ + + + +++E+EK+ A RE ERE +A Y+
Sbjct 49 NHSGNKPDPPPVLRVDDRQRLARERREEREKQL------AARETVWLEREERARQ--HYE 100
Query 750 YATEEEKIQLDLKKALEDIEKAKISDAEKAQLKVKAEK 787
E K +L+ ++ E+ +A + + + +L+ E+
Sbjct 101 RHLEARKKKLEDQRLKEERRRAAVEEKRRQRLEEDKER 138
Score = 22.3 bits (46), Expect = 4.3
Identities = 9/16 (56%), Positives = 9/16 (56%), Gaps = 0/16 (0%)
Query 1120 MANGGVGGDAAASGDG 1135
MA G GGD GDG
Sbjct 1 MAEQGAGGDGHRGGDG 16
>Q12QI1 Translation initiation factor IF-2 [Shewanella denitrificans
(strain OS217 / ATCC BAA-1090 / DSM 15013)]
Length=884
Score = 34.7 bits (78), Expect = 8e-04
Identities = 55/279 (20%), Positives = 104/279 (37%), Gaps = 43/279 (15%)
Query 653 TTWNDAASKAGTSWKTAWENISGASEKGGK--------KFQLL-FLKDPNATDESPKPSP 703
T+ A++ G S + E S A K G+ K QLL +LK + D++P
Sbjct 4 TSVQKLAAEVGKSVERLIEQFSEAGLKKGQADTVSETEKQQLLDYLKKQHGADKAPTKMT 63
Query 704 LP-----TFNPNRGIGTGKKDEKEKKPK-------------------KGKSDAER----- 734
L T + G G K + E + K K K++A+
Sbjct 64 LQRKTVSTLSVPAGGGQSKDVKVEVRKKRTFVKRDDSELVDQAELEAKAKAEADAKAAAE 123
Query 735 -----EAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDAEKAQLKVKAEKVA 789
+AE +AKA A+ + K + K + A + + K E A + +AE++
Sbjct 124 AKQKADAEAQAKAAAEAKAKAEANKAKEKAPQAPAPKPKAELKAETPEAAAARAEAERIK 183
Query 790 SDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDANKISNAQKVQMEK 849
+ + L +Q E+ + E+ A ++R + E+ ++A+ + + KV
Sbjct 184 ATQEAVLTKKQKEEAAQAAEEAKKLAEVNSKRWAEEERLRLEAEKNGDHHVTTSKVARAA 243
Query 850 QLEDQLRAIKRNGLEERLKLEEQYSSISGKSGNQSRITN 888
+ + KR ++ + G + + N
Sbjct 244 EDSSDMDDEKRGRRARNKPTNKKRGGKDARDGREKHMRN 282
Lambda K H a alpha
0.313 0.129 0.351 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 23399766
Database: f52c1c9468f2666c714994d232747058.SwissProt.fasta
Posted date: May 31, 2024 6:50 PM
Number of letters in database: 22,294
Number of sequences in database: 17
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
